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avrg: A549 cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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ISMARA results avrg: A549 cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

ISMARA - Integrated System for Motif Actitivity Response Analysis is a free online tool that recognizes most important transcription factors that are changing their activity in a set of samples.

Original results

Sample Condition
CoV002-CoV2-1-indexG4_S401_SARS-CoV-2_infected_A549
CoV002-CoV2-2-indexG5_S501_SARS-CoV-2_infected_A549
CoV002-CoV2-3-indexG6_S601_SARS-CoV-2_infected_A549
CoV002-mock1-indexG1_S102_mock_A549
CoV002-mock2-indexG2_S202_mock_A549
CoV002-mock3-indexG3_S302_mock_A549

All motifs sorted by activity significance

Motif name Z-value Associated genes Profile Logo
IRF2_STAT2_IRF8_IRF1 17.30 small profile SeqLogo of IRF2_STAT2_IRF8_IRF1
IRF9 12.51 small profile SeqLogo of IRF9
IRF6_IRF4_IRF5 10.46 small profile SeqLogo of IRF6_IRF4_IRF5
IRF3 7.11 small profile SeqLogo of IRF3
SP1 3.36 small profile SeqLogo of SP1
IRF7 3.31 small profile SeqLogo of IRF7
SMAD1 3.22 small profile SeqLogo of SMAD1
CEBPA 2.99 small profile SeqLogo of CEBPA
RELA 2.97 small profile SeqLogo of RELA
NFE2L1 2.69 small profile SeqLogo of NFE2L1
POU3F2 2.66 small profile SeqLogo of POU3F2
E2F7_E2F1 2.59 small profile SeqLogo of E2F7_E2F1
ELK4_ETV5_ELK1_ELK3_ELF4 2.46 small profile SeqLogo of ELK4_ETV5_ELK1_ELK3_ELF4
CDC5L 2.45 small profile SeqLogo of CDC5L
TBX15_MGA 2.39 small profile SeqLogo of TBX15_MGA
GLIS2 2.35 small profile SeqLogo of GLIS2
BATF 2.33 small profile SeqLogo of BATF
POU2F1 2.33 small profile SeqLogo of POU2F1
DLX4_HOXD8 2.31 small profile SeqLogo of DLX4_HOXD8
STAT5A 2.28 small profile SeqLogo of STAT5A
CEBPE_CEBPD 2.25 small profile SeqLogo of CEBPE_CEBPD
TCF12_ASCL2 2.25 small profile SeqLogo of TCF12_ASCL2
SREBF1_TFE3 2.25 small profile SeqLogo of SREBF1_TFE3
FOXC1 2.20 small profile SeqLogo of FOXC1
PRDM1 2.20 small profile SeqLogo of PRDM1
PATZ1_KLF4 2.20 small profile SeqLogo of PATZ1_KLF4
SMAD4 2.19 small profile SeqLogo of SMAD4
MAZ_ZNF281_GTF2F1 2.15 small profile SeqLogo of MAZ_ZNF281_GTF2F1
POU5F1_POU2F3 2.08 small profile SeqLogo of POU5F1_POU2F3
SP4_PML 2.01 small profile SeqLogo of SP4_PML
CLOCK 2.00 small profile SeqLogo of CLOCK
ONECUT1 1.98 small profile SeqLogo of ONECUT1
MYBL2 1.97 small profile SeqLogo of MYBL2
HSFY2 1.95 small profile SeqLogo of HSFY2
BACH1_NFE2_NFE2L2 1.93 small profile SeqLogo of BACH1_NFE2_NFE2L2
NFIX_NFIB 1.93 small profile SeqLogo of NFIX_NFIB
FLI1 1.92 small profile SeqLogo of FLI1
TFAP2C 1.91 small profile SeqLogo of TFAP2C
ZBTB33_CHD2 1.91 small profile SeqLogo of ZBTB33_CHD2
KLF12 1.90 small profile SeqLogo of KLF12
KLF1 1.86 small profile SeqLogo of KLF1
PAX7_NOBOX 1.86 small profile SeqLogo of PAX7_NOBOX
HIF1A 1.85 small profile SeqLogo of HIF1A
ESRRA_ESR2 1.84 small profile SeqLogo of ESRRA_ESR2
TFCP2 1.82 small profile SeqLogo of TFCP2
HIC1 1.82 small profile SeqLogo of HIC1
RUNX1_RUNX2 1.78 small profile SeqLogo of RUNX1_RUNX2
DPRX 1.74 small profile SeqLogo of DPRX
SMAD2 1.74 small profile SeqLogo of SMAD2
AAUACUG 1.73 small profile SeqLogo of AAUACUG
PBX3 1.72 small profile SeqLogo of PBX3
TFAP4_MSC 1.69 small profile SeqLogo of TFAP4_MSC
FOXQ1 1.67 small profile SeqLogo of FOXQ1
PLAGL1 1.66 small profile SeqLogo of PLAGL1
CCCUGAG 1.64 small profile SeqLogo of CCCUGAG
CXXC1 1.61 small profile SeqLogo of CXXC1
ID4_TCF4_SNAI2 1.60 small profile SeqLogo of ID4_TCF4_SNAI2
MEIS3_TGIF2LX 1.60 small profile SeqLogo of MEIS3_TGIF2LX
NR3C1 1.58 small profile SeqLogo of NR3C1
GMEB1 1.56 small profile SeqLogo of GMEB1
DBX2_HLX 1.55 small profile SeqLogo of DBX2_HLX
SP100 1.55 small profile SeqLogo of SP100
EGR1_EGR4 1.54 small profile SeqLogo of EGR1_EGR4
FOSL1 1.54 small profile SeqLogo of FOSL1
GTF2I 1.51 small profile SeqLogo of GTF2I
TCF3_MYOG 1.51 small profile SeqLogo of TCF3_MYOG
RFX3_RFX2 1.50 small profile SeqLogo of RFX3_RFX2
RCOR1_MTA3 1.47 small profile SeqLogo of RCOR1_MTA3
TCF21 1.47 small profile SeqLogo of TCF21
TP63 1.46 small profile SeqLogo of TP63
PPARA 1.43 small profile SeqLogo of PPARA
HMX1 1.43 small profile SeqLogo of HMX1
TLX2 1.42 small profile SeqLogo of TLX2
OLIG2_NEUROD1_ATOH1 1.41 small profile SeqLogo of OLIG2_NEUROD1_ATOH1
ZBTB18 1.40 small profile SeqLogo of ZBTB18
CUUUGGU 1.39 small profile SeqLogo of CUUUGGU
NHLH1 1.38 small profile SeqLogo of NHLH1
TBX2 1.37 small profile SeqLogo of TBX2
TFEC_MITF_ARNTL_BHLHE41 1.37 small profile SeqLogo of TFEC_MITF_ARNTL_BHLHE41
SHOX2_HOXC5 1.37 small profile SeqLogo of SHOX2_HOXC5
CREB5_CREM_JUNB 1.36 small profile SeqLogo of CREB5_CREM_JUNB
HES1 1.35 small profile SeqLogo of HES1
ZBTB6 1.35 small profile SeqLogo of ZBTB6
NFKB1 1.35 small profile SeqLogo of NFKB1
NKX3-2 1.35 small profile SeqLogo of NKX3-2
CEBPG 1.33 small profile SeqLogo of CEBPG
HOXB8 1.33 small profile SeqLogo of HOXB8
MYF6 1.32 small profile SeqLogo of MYF6
TBP 1.31 small profile SeqLogo of TBP
BARHL1 1.30 small profile SeqLogo of BARHL1
FOXM1_TBL1XR1 1.29 small profile SeqLogo of FOXM1_TBL1XR1
SOX14 1.28 small profile SeqLogo of SOX14
MXI1_MYC_MYCN 1.27 small profile SeqLogo of MXI1_MYC_MYCN
PITX1 1.26 small profile SeqLogo of PITX1
GLI3 1.25 small profile SeqLogo of GLI3
NKX2-1 1.24 small profile SeqLogo of NKX2-1
TLX1_NFIC 1.24 small profile SeqLogo of TLX1_NFIC
EN1_ESX1_GBX1 1.24 small profile SeqLogo of EN1_ESX1_GBX1
GMEB2 1.22 small profile SeqLogo of GMEB2
PAX6 1.21 small profile SeqLogo of PAX6
PAX3 1.21 small profile SeqLogo of PAX3
ZNF384 1.21 small profile SeqLogo of ZNF384
E2F3 1.20 small profile SeqLogo of E2F3
RFX7_RFX4_RFX1 1.20 small profile SeqLogo of RFX7_RFX4_RFX1
RARA 1.19 small profile SeqLogo of RARA
TAF1 1.18 small profile SeqLogo of TAF1
BARX1 1.18 small profile SeqLogo of BARX1
MEF2C 1.18 small profile SeqLogo of MEF2C
NFKB2 1.18 small profile SeqLogo of NFKB2
ESRRB_ESRRG 1.18 small profile SeqLogo of ESRRB_ESRRG
NR5A2 1.17 small profile SeqLogo of NR5A2
HSF4 1.16 small profile SeqLogo of HSF4
MBD2 1.15 small profile SeqLogo of MBD2
ELF3_EHF 1.15 small profile SeqLogo of ELF3_EHF
HIC2 1.15 small profile SeqLogo of HIC2
TCF7L1 1.13 small profile SeqLogo of TCF7L1
OTP_PHOX2B_LHX1_LMX1A_LHX5_HOXC4 1.12 small profile SeqLogo of OTP_PHOX2B_LHX1_LMX1A_LHX5_HOXC4
ZNF652 1.12 small profile SeqLogo of ZNF652
ETV1_ERF_FEV_ELF1 1.12 small profile SeqLogo of ETV1_ERF_FEV_ELF1
UUGGCAC 1.11 small profile SeqLogo of UUGGCAC
KLF14_SP8 1.11 small profile SeqLogo of KLF14_SP8
MAF_NRL 1.11 small profile SeqLogo of MAF_NRL
NANOG 1.10 small profile SeqLogo of NANOG
GLI2 1.09 small profile SeqLogo of GLI2
HOXB2_UNCX_HOXD3 1.09 small profile SeqLogo of HOXB2_UNCX_HOXD3
SOX7 1.09 small profile SeqLogo of SOX7
PKNOX1_TGIF2 1.09 small profile SeqLogo of PKNOX1_TGIF2
BARHL2 1.08 small profile SeqLogo of BARHL2
EZH2 1.07 small profile SeqLogo of EZH2
SIX1_SIX3_SIX2 1.07 small profile SeqLogo of SIX1_SIX3_SIX2
MECOM 1.07 small profile SeqLogo of MECOM
XBP1 1.06 small profile SeqLogo of XBP1
CUX2 1.06 small profile SeqLogo of CUX2
MAFA 1.06 small profile SeqLogo of MAFA
INSM1 1.06 small profile SeqLogo of INSM1
ZIC1 1.05 small profile SeqLogo of ZIC1
OTX2_CRX 1.05 small profile SeqLogo of OTX2_CRX
NR1I2 1.04 small profile SeqLogo of NR1I2
POU2F2_POU3F1 1.04 small profile SeqLogo of POU2F2_POU3F1
SOX30 1.03 small profile SeqLogo of SOX30
AAAGUGC 1.02 small profile SeqLogo of AAAGUGC
SOX5 1.02 small profile SeqLogo of SOX5
DUXA 1.02 small profile SeqLogo of DUXA
ZEB1 1.01 small profile SeqLogo of ZEB1
NR2F2 1.01 small profile SeqLogo of NR2F2
RXRG 1.01 small profile SeqLogo of RXRG
IKZF1 0.98 small profile SeqLogo of IKZF1
MZF1 0.98 small profile SeqLogo of MZF1
HSF2 0.98 small profile SeqLogo of HSF2
ZNF148 0.98 small profile SeqLogo of ZNF148
E2F4 0.98 small profile SeqLogo of E2F4
PAX8 0.97 small profile SeqLogo of PAX8
FOXA1 0.96 small profile SeqLogo of FOXA1
GZF1 0.96 small profile SeqLogo of GZF1
ETS1 0.96 small profile SeqLogo of ETS1
HOXC12_HOXD12 0.96 small profile SeqLogo of HOXC12_HOXD12
JUN 0.96 small profile SeqLogo of JUN
PBX1 0.95 small profile SeqLogo of PBX1
CAGUAGU 0.95 small profile SeqLogo of CAGUAGU
ZNF263 0.94 small profile SeqLogo of ZNF263
E2F2_E2F5 0.94 small profile SeqLogo of E2F2_E2F5
BPTF 0.93 small profile SeqLogo of BPTF
FOXN1 0.93 small profile SeqLogo of FOXN1
AGCAGCA 0.92 small profile SeqLogo of AGCAGCA
GAGGUAG 0.92 small profile SeqLogo of GAGGUAG
HMX3 0.92 small profile SeqLogo of HMX3
PDX1 0.92 small profile SeqLogo of PDX1
BHLHE22_BHLHA15_BHLHE23 0.91 small profile SeqLogo of BHLHE22_BHLHA15_BHLHE23
AAGGCAC 0.90 small profile SeqLogo of AAGGCAC
PAX4 0.90 small profile SeqLogo of PAX4
FOXL1 0.88 small profile SeqLogo of FOXL1
E2F6 0.88 small profile SeqLogo of E2F6
HOXA5 0.87 small profile SeqLogo of HOXA5
EGR3_EGR2 0.87 small profile SeqLogo of EGR3_EGR2
UGGUCCC 0.87 small profile SeqLogo of UGGUCCC
STAT5B 0.86 small profile SeqLogo of STAT5B
AUAAAGU 0.85 small profile SeqLogo of AUAAAGU
HOXA13 0.85 small profile SeqLogo of HOXA13
CUGGCUG 0.84 small profile SeqLogo of CUGGCUG
DMC1 0.84 small profile SeqLogo of DMC1
SP3 0.84 small profile SeqLogo of SP3
TFDP1 0.83 small profile SeqLogo of TFDP1
UGCAUAG 0.83 small profile SeqLogo of UGCAUAG
CUX1 0.83 small profile SeqLogo of CUX1
YBX1_FOS_NFYC_NFYA_NFYB_CEBPZ 0.83 small profile SeqLogo of YBX1_FOS_NFYC_NFYA_NFYB_CEBPZ
DDIT3 0.82 small profile SeqLogo of DDIT3
GGCUCAG 0.82 small profile SeqLogo of GGCUCAG
MSX1 0.81 small profile SeqLogo of MSX1
NR4A1 0.81 small profile SeqLogo of NR4A1
ARNT 0.81 small profile SeqLogo of ARNT
NKX2-4 0.80 small profile SeqLogo of NKX2-4
NRF1 0.80 small profile SeqLogo of NRF1
FOXA2_FOXJ3 0.80 small profile SeqLogo of FOXA2_FOXJ3
ELF2_GABPA_ELF5 0.79 small profile SeqLogo of ELF2_GABPA_ELF5
UUGGCAA 0.78 small profile SeqLogo of UUGGCAA
ETV6 0.78 small profile SeqLogo of ETV6
SRF 0.78 small profile SeqLogo of SRF
GGCAGUG 0.77 small profile SeqLogo of GGCAGUG
EBF3 0.77 small profile SeqLogo of EBF3
GGAAUGU 0.77 small profile SeqLogo of GGAAUGU
MAFB 0.76 small profile SeqLogo of MAFB
FOXD1_FOXO1_FOXO6_FOXG1_FOXP1 0.76 small profile SeqLogo of FOXD1_FOXO1_FOXO6_FOXG1_FOXP1
POU4F1_POU4F3 0.76 small profile SeqLogo of POU4F1_POU4F3
E2F8 0.75 small profile SeqLogo of E2F8
HOXA1 0.75 small profile SeqLogo of HOXA1
SOX21 0.75 small profile SeqLogo of SOX21
FOSB 0.74 small profile SeqLogo of FOSB
PPARG 0.74 small profile SeqLogo of PPARG
SOX9 0.74 small profile SeqLogo of SOX9
MEIS1 0.74 small profile SeqLogo of MEIS1
RARB 0.74 small profile SeqLogo of RARB
EPAS1_BCL3 0.73 small profile SeqLogo of EPAS1_BCL3
SIX4 0.73 small profile SeqLogo of SIX4
HOXA4 0.73 small profile SeqLogo of HOXA4
ATF4 0.73 small profile SeqLogo of ATF4
NKX2-6 0.72 small profile SeqLogo of NKX2-6
HOXD10 0.72 small profile SeqLogo of HOXD10
CEBPB 0.72 small profile SeqLogo of CEBPB
SIN3A_CHD1 0.72 small profile SeqLogo of SIN3A_CHD1
DLX1_HOXA3_BARX2 0.72 small profile SeqLogo of DLX1_HOXA3_BARX2
HSF1 0.72 small profile SeqLogo of HSF1
DBP 0.72 small profile SeqLogo of DBP
CENPB 0.71 small profile SeqLogo of CENPB
NFAT5 0.71 small profile SeqLogo of NFAT5
HMX2 0.71 small profile SeqLogo of HMX2
ZBTB16 0.71 small profile SeqLogo of ZBTB16
BCL6B 0.70 small profile SeqLogo of BCL6B
HOXC8 0.70 small profile SeqLogo of HOXC8
ZNF333 0.70 small profile SeqLogo of ZNF333
PROX1 0.70 small profile SeqLogo of PROX1
PITX3 0.69 small profile SeqLogo of PITX3
ZNF350 0.69 small profile SeqLogo of ZNF350
NR4A2 0.69 small profile SeqLogo of NR4A2
HIVEP1 0.68 small profile SeqLogo of HIVEP1
OSR1_OSR2 0.68 small profile SeqLogo of OSR1_OSR2
ACUGCAU 0.68 small profile SeqLogo of ACUGCAU
EOMES 0.68 small profile SeqLogo of EOMES
RFX5 0.68 small profile SeqLogo of RFX5
NR0B1 0.67 small profile SeqLogo of NR0B1
PLAG1 0.67 small profile SeqLogo of PLAG1
STAT6 0.67 small profile SeqLogo of STAT6
MAFF_MAFG 0.66 small profile SeqLogo of MAFF_MAFG
TGIF1 0.66 small profile SeqLogo of TGIF1
AGUGCUU 0.66 small profile SeqLogo of AGUGCUU
TP73 0.66 small profile SeqLogo of TP73
ZNF232 0.66 small profile SeqLogo of ZNF232
UAAGGCA 0.66 small profile SeqLogo of UAAGGCA
EBF1 0.66 small profile SeqLogo of EBF1
RELB 0.66 small profile SeqLogo of RELB
ZSCAN4 0.65 small profile SeqLogo of ZSCAN4
JUND 0.65 small profile SeqLogo of JUND
TCF7L2 0.64 small profile SeqLogo of TCF7L2
IRX5 0.64 small profile SeqLogo of IRX5
HOXD11_HOXA11 0.64 small profile SeqLogo of HOXD11_HOXA11
TFAP2E 0.64 small profile SeqLogo of TFAP2E
SOX11 0.64 small profile SeqLogo of SOX11
AGCACCA 0.64 small profile SeqLogo of AGCACCA
ACAGUAU 0.64 small profile SeqLogo of ACAGUAU
SPI1 0.63 small profile SeqLogo of SPI1
GCM1 0.63 small profile SeqLogo of GCM1
GGCAAGA 0.63 small profile SeqLogo of GGCAAGA
HOMEZ 0.63 small profile SeqLogo of HOMEZ
AUGGCAC 0.62 small profile SeqLogo of AUGGCAC
NKX6-2 0.62 small profile SeqLogo of NKX6-2
FUBP1 0.62 small profile SeqLogo of FUBP1
STAT4 0.62 small profile SeqLogo of STAT4
ACAUUCA 0.61 small profile SeqLogo of ACAUUCA
TFCP2L1 0.61 small profile SeqLogo of TFCP2L1
ZNF524 0.61 small profile SeqLogo of ZNF524
TEAD4 0.61 small profile SeqLogo of TEAD4
DLX5 0.60 small profile SeqLogo of DLX5
NR2E3 0.60 small profile SeqLogo of NR2E3
PGR 0.60 small profile SeqLogo of PGR
HNF4G 0.60 small profile SeqLogo of HNF4G
VENTX 0.59 small profile SeqLogo of VENTX
AGUGCAA 0.59 small profile SeqLogo of AGUGCAA
POU3F3_POU3F4 0.58 small profile SeqLogo of POU3F3_POU3F4
NR2C1 0.58 small profile SeqLogo of NR2C1
GUAAACA 0.58 small profile SeqLogo of GUAAACA
GCUGGUG 0.57 small profile SeqLogo of GCUGGUG
HOXB7 0.57 small profile SeqLogo of HOXB7
SPIC 0.57 small profile SeqLogo of SPIC
ZNF282 0.57 small profile SeqLogo of ZNF282
HNF1A_HNF1B 0.56 small profile SeqLogo of HNF1A_HNF1B
CTCF_CTCFL 0.56 small profile SeqLogo of CTCF_CTCFL
FOXD3_FOXI1_FOXF1 0.56 small profile SeqLogo of FOXD3_FOXI1_FOXF1
AR_NR3C2 0.55 small profile SeqLogo of AR_NR3C2
MESP1 0.55 small profile SeqLogo of MESP1
TBX21_TBR1 0.55 small profile SeqLogo of TBX21_TBR1
WRNIP1 0.55 small profile SeqLogo of WRNIP1
TBX3 0.55 small profile SeqLogo of TBX3
HLF_TEF 0.55 small profile SeqLogo of HLF_TEF
WT1_MTF1_ZBTB7B 0.55 small profile SeqLogo of WT1_MTF1_ZBTB7B
ARID5B 0.55 small profile SeqLogo of ARID5B
PPARD 0.54 small profile SeqLogo of PPARD
SOX1 0.54 small profile SeqLogo of SOX1
NKX1-1 0.54 small profile SeqLogo of NKX1-1
AUUGCAC 0.53 small profile SeqLogo of AUUGCAC
ATF7 0.53 small profile SeqLogo of ATF7
HOXC6_HOXA7 0.53 small profile SeqLogo of HOXC6_HOXA7
VDR 0.53 small profile SeqLogo of VDR
ZNF8 0.53 small profile SeqLogo of ZNF8
TAL1 0.52 small profile SeqLogo of TAL1
NKX3-1 0.52 small profile SeqLogo of NKX3-1
HINFP 0.52 small profile SeqLogo of HINFP
GSC_GSC2 0.52 small profile SeqLogo of GSC_GSC2
CBFB 0.52 small profile SeqLogo of CBFB