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GSE55662: Plasticity of transcriptional regulation under antibiotic stress
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Results for SoxS
Z-value: 1.13
Transcription factors associated with SoxS
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| soxS | 0.66 | 7.6e-02 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| fldA-uof-fur Show fit | 4.97 |
Fur transcriptional dual regulator RyhB-regulated fur leader peptide flavodoxin 1 |
||
| tolC-ygiABC Show fit | 3.97 |
predicted enzyme with ATPase activity conserved outer membrane protein predicted protein TolC outer membrane channel |
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| sodA Show fit | 3.97 |
superoxide dismutase (Mn) |
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| uof-fur Show fit | 3.76 |
Fur transcriptional dual regulator RyhB-regulated fur leader peptide |
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| soxS Show fit | 3.32 |
SoxS DNA-binding transcriptional dual regulator |
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| zwf Show fit | 2.58 |
glucose-6-phosphate dehydrogenase (NADP+) |
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| ribA Show fit | 2.41 |
GTP cyclohydrolase II |
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| ydbK Show fit | 2.38 |
pyruvate:flavodoxin oxidoreductase |
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| fumC Show fit | 2.26 |
fumarase C |
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| rob Show fit | 2.02 |
Rob DNA-binding transcriptional dual regulator |
Network of associatons between targets according to the STRING database.
First level regulatory network of SoxS
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 8.7 | GO:0006417 | regulation of translation(GO:0006417) |
| 1.3 | 4.0 | GO:0006801 | superoxide metabolic process(GO:0006801) |
| 0.7 | 4.0 | GO:0015891 | siderophore transport(GO:0015891) |
| 0.9 | 2.6 | GO:0009372 | quorum sensing(GO:0009372) |
| 0.6 | 2.4 | GO:0042727 | riboflavin metabolic process(GO:0006771) riboflavin biosynthetic process(GO:0009231) flavin-containing compound metabolic process(GO:0042726) flavin-containing compound biosynthetic process(GO:0042727) |
| 0.8 | 2.3 | GO:0006108 | malate metabolic process(GO:0006108) |
| 0.0 | 2.0 | GO:2001141 | regulation of transcription, DNA-templated(GO:0006355) regulation of nucleic acid-templated transcription(GO:1903506) regulation of RNA biosynthetic process(GO:2001141) |
| 0.2 | 1.4 | GO:0006855 | drug transmembrane transport(GO:0006855) |
| 0.1 | 1.2 | GO:0034599 | cellular response to oxidative stress(GO:0034599) |
| 0.4 | 1.1 | GO:1900232 | negative regulation of organelle organization(GO:0010639) negative regulation of cell projection organization(GO:0031345) post-translational protein modification(GO:0043687) response to alcohol(GO:0097305) regulation of single-species biofilm formation on inanimate substrate(GO:1900231) negative regulation of single-species biofilm formation on inanimate substrate(GO:1900232) negative regulation of organelle assembly(GO:1902116) negative regulation of bacterial-type flagellum assembly(GO:1902209) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 16.6 | GO:0005829 | cytosol(GO:0005829) |
| 0.1 | 5.4 | GO:1990351 | transmembrane transporter complex(GO:1902495) transporter complex(GO:1990351) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 7.4 | GO:0008270 | zinc ion binding(GO:0008270) |
| 1.3 | 4.0 | GO:0016721 | superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721) |
| 0.6 | 4.0 | GO:0015562 | efflux transmembrane transporter activity(GO:0015562) |
| 1.1 | 3.3 | GO:0001098 | basal transcription machinery binding(GO:0001098) bacterial-type RNA polymerase holo enzyme binding(GO:0001108) |
| 0.1 | 2.6 | GO:0016616 | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor(GO:0016616) |
| 0.6 | 2.4 | GO:0019238 | cyclohydrolase activity(GO:0019238) |
| 0.5 | 2.3 | GO:0004333 | fumarate hydratase activity(GO:0004333) |
| 0.0 | 2.0 | GO:0043565 | sequence-specific DNA binding(GO:0043565) |
| 0.5 | 1.4 | GO:0015307 | drug:proton antiporter activity(GO:0015307) |
| 0.1 | 1.2 | GO:0016861 | intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861) |