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GSE55662: Plasticity of transcriptional regulation under antibiotic stress

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Results for RcdA

Z-value: 1.04

Transcription factors associated with RcdA

Gene Symbol Gene ID Gene Info
rcdA
rcdA RcdA DNA-binding transcriptional regulator

Activity profile of RcdA motif

Sorted Z-values of RcdA motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
yagK 8.49
yagK
CP4-6 prophage; conserved protein
ydeI 7.25
ydeI
stress response protein
csgDEFG 4.53
csgG
csgF
csgE
csgD
curli secretion channel
curli assembly component
curli transport specificity factor
CsgD DNA-binding transcriptional dual regulator
bluF 4.14
bluF
blue light-responsive regulator of BluR
asr 2.57
asr
acid shock protein

Network of associatons between targets according to the STRING database.

First level regulatory network of RcdA

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 7.2 GO:0070301 cellular response to hydrogen peroxide(GO:0070301)
1.0 4.1 GO:0043433 negative regulation of sequence-specific DNA binding transcription factor activity(GO:0043433)
0.8 4.5 GO:1900190 regulation of multi-organism process(GO:0043900) regulation of single-species biofilm formation(GO:1900190)
0.4 2.6 GO:0010043 response to zinc ion(GO:0010043)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 4.5 GO:0031246 intrinsic component of periplasmic side of cell outer membrane(GO:0031246)
0.0 2.6 GO:0042597 periplasmic space(GO:0042597)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 4.1 GO:0008134 transcription factor binding(GO:0008134)
0.2 4.5 GO:0000987 bacterial-type RNA polymerase core promoter proximal region sequence-specific DNA binding(GO:0000986) core promoter proximal region sequence-specific DNA binding(GO:0000987) core promoter proximal region DNA binding(GO:0001159)