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GSE55662: Plasticity of transcriptional regulation under antibiotic stress
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Results for PhoB
Z-value: 2.17
Transcription factors associated with PhoB
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| phoB | 0.57 | 1.4e-01 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| pitB Show fit | 9.66 |
metal phosphate:H+ symporter PitB |
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| ugpBAECQ Show fit | 8.19 |
glycerol-3-phosphate ABC transporter - membrane subunit glycerol-3-phosphate ABC transporter - membrane subunit glycerol-3-phosphate ABC transporter - periplasmic binding protein glycerol-3-phosphate ABC transporter - ATP binding subunit glycerophosphodiester phosphodiesterase, cytosolic |
||
| cusCFBA Show fit | 6.81 |
copper / silver exporter - membrane subunit copper / silver exporter - outer membrane porin copper / silver exporter - membrane fusion protein copper / silver exporter - periplasmic binding protein and metallochaperone |
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| gadX Show fit | 5.65 |
GadX DNA-binding transcriptional dual regulator |
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| psiE Show fit | 4.96 |
predicted phosphate starvation-inducible protein |
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| waaH Show fit | 4.96 |
UDP-glucuronate:LPS(HepIII) glycosyltransferase |
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| gadXW Show fit | 4.82 |
GadW DNA-binding transcriptional dual regulator GadX DNA-binding transcriptional dual regulator |
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| prpR Show fit | 4.78 |
PrpR DNA-binding transcriptional dual regulator |
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| phoBR Show fit | 3.93 |
PhoR PhoB transcriptional dual regulator |
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| feaR Show fit | 3.81 |
FeaR DNA-binding transcriptional activator |
Network of associatons between targets according to the STRING database.
First level regulatory network of PhoB
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 19.3 | GO:1903508 | positive regulation of transcription, DNA-templated(GO:0045893) positive regulation of RNA metabolic process(GO:0051254) positive regulation of RNA biosynthetic process(GO:1902680) positive regulation of nucleic acid-templated transcription(GO:1903508) |
| 2.1 | 14.9 | GO:0035435 | phosphate ion transmembrane transport(GO:0035435) inorganic anion transmembrane transport(GO:0098661) |
| 1.8 | 8.9 | GO:0016036 | cellular response to phosphate starvation(GO:0016036) |
| 2.0 | 8.2 | GO:0015748 | organophosphate ester transport(GO:0015748) |
| 2.5 | 7.4 | GO:0010272 | response to silver ion(GO:0010272) |
| 1.1 | 3.3 | GO:0010350 | cellular response to magnesium starvation(GO:0010350) |
| 1.0 | 2.9 | GO:0046391 | 5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391) |
| 0.5 | 2.5 | GO:0010043 | response to zinc ion(GO:0010043) |
| 0.1 | 1.8 | GO:0016311 | dephosphorylation(GO:0016311) |
| 1.3 | 1.3 | GO:0010921 | regulation of phosphatase activity(GO:0010921) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 25.4 | GO:0005886 | plasma membrane(GO:0005886) |
| 0.1 | 11.1 | GO:0042597 | periplasmic space(GO:0042597) |
| 0.7 | 8.2 | GO:0055052 | ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing(GO:0055052) |
| 0.2 | 6.0 | GO:1904949 | ATP-binding cassette (ABC) transporter complex(GO:0043190) ATPase dependent transmembrane transport complex(GO:0098533) ATPase complex(GO:1904949) |
| 0.4 | 2.9 | GO:0061695 | transferase complex, transferring phosphorus-containing groups(GO:0061695) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 2.8 | 22.5 | GO:1901677 | phosphate transmembrane transporter activity(GO:1901677) |
| 1.2 | 10.5 | GO:0001140 | transcriptional activator activity, bacterial-type RNA polymerase core promoter proximal region sequence-specific binding(GO:0001140) |
| 0.1 | 8.0 | GO:0003700 | transcription factor activity, sequence-specific DNA binding(GO:0003700) |
| 1.7 | 6.8 | GO:0016530 | metallochaperone activity(GO:0016530) |
| 0.6 | 5.0 | GO:0008194 | UDP-glycosyltransferase activity(GO:0008194) |
| 1.3 | 3.9 | GO:0001098 | basal transcription machinery binding(GO:0001098) bacterial-type RNA polymerase holo enzyme binding(GO:0001108) |
| 0.3 | 3.8 | GO:0001159 | bacterial-type RNA polymerase core promoter proximal region sequence-specific DNA binding(GO:0000986) core promoter proximal region sequence-specific DNA binding(GO:0000987) core promoter proximal region DNA binding(GO:0001159) |
| 0.3 | 3.3 | GO:0004721 | phosphorelay sensor kinase activity(GO:0000155) protein histidine kinase activity(GO:0004673) phosphoprotein phosphatase activity(GO:0004721) |
| 0.5 | 2.9 | GO:0008080 | N-acetyltransferase activity(GO:0008080) phosphotransferase activity, phosphate group as acceptor(GO:0016776) |
| 0.1 | 1.8 | GO:0016791 | phosphatase activity(GO:0016791) |