Project

GSE55662: Plasticity of transcriptional regulation under antibiotic stress

Navigation
Downloads

Results for PhoB

Z-value: 2.17

Transcription factors associated with PhoB

Gene Symbol Gene ID Gene Info
phoB PhoB transcriptional dual regulator

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
phoB0.571.4e-01Click!

Activity profile of PhoB motif

Sorted Z-values of PhoB motif

Promoter Log-likelihood Transcript Gene Gene Info
pitB 9.66 metal phosphate:H+ symporter PitB
ugpBAECQ 8.19 glycerol-3-phosphate ABC transporter - membrane subunit
glycerol-3-phosphate ABC transporter - membrane subunit
glycerol-3-phosphate ABC transporter - periplasmic binding protein
glycerol-3-phosphate ABC transporter - ATP binding subunit
glycerophosphodiester phosphodiesterase, cytosolic
cusCFBA 6.81 copper / silver exporter - membrane subunit
copper / silver exporter - outer membrane porin
copper / silver exporter - membrane fusion protein
copper / silver exporter - periplasmic binding protein and metallochaperone
gadX 5.65 GadX DNA-binding transcriptional dual regulator
psiE 4.96 predicted phosphate starvation-inducible protein
waaH 4.96 UDP-glucuronate:LPS(HepIII) glycosyltransferase
gadXW 4.82 GadW DNA-binding transcriptional dual regulator
GadX DNA-binding transcriptional dual regulator
prpR 4.78 PrpR DNA-binding transcriptional dual regulator
phoBR 3.93 PhoR
PhoB transcriptional dual regulator
feaR 3.81 FeaR DNA-binding transcriptional activator
phoQ 3.26 PhoQ sensory histidine kinase
yhjC 2.96 predicted DNA-binding transcriptional regulator
phoE 2.88 outer membrane porin E
phnCDE_1E_2FGHIJKLMNOP 2.85 5-phospho-α-D-ribosyl 1,2-cyclic phosphate phosphodiesterase
PhnL subunit of methylphosphonate degradation complex
PhnF predicted transcriptional regulator
carbon-phosphorus lyase core complex, PhnG subunit
phosphonate ABC transporter - periplasmic binding protein
phosphonate ABC transporter - ATP binding subunit
aminoalkylphosphonate N-acetyltransferase
ribose 1,5-bisphosphokinase
phosphonate ABC transporter - membrane subunit
phosphonate/organophosphate ester transporter (pseudogene)
RPnTP hydrolase
carbon-phosphorus lyase core complex, PhnJ subunit
predicted carbon-phosphorus lyase subunit
carbon-phosphorus lyase core complex, PhnH subunit
carbon-phosphorus lyase core complex, PhnI subunit
pstSCA 2.73 phosphate ABC transporter - periplasmic binding protein
phosphate ABC transporter - membrane subunit
phosphate ABC transporter - membrane subunit
asr 2.48 acid shock protein
pstSCAB-phoU 1.92 phosphate ABC transporter - periplasmic binding protein
phosphate ABC transporter - membrane subunit
phosphate ABC transporter - membrane subunit
negative regulator of the pho regulon
phosphate ABC transporter - ATP binding subunit
phoA-psiF 1.82 alkaline phosphatase
conserved protein
yegH 1.36 inner membrane protein YegH
pstS 1.30 phosphate ABC transporter - periplasmic binding protein
phoH 1.10 ATP-binding protein
adiC 1.01 AdiC arginine:agmatine antiporter
cusRS 0.62 CusS sensory histidine kinase
CusR transcriptional activator
phoU 0.57 negative regulator of the pho regulon
argP 0.23 ArgP transcriptional activator
cra 0.23 Cra DNA-binding transcriptional dual regulator

Network of associatons between targets according to the STRING database.

First level regulatory network of PhoB

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.5 7.4 GO:0010272 response to silver ion(GO:0010272)
2.1 14.9 GO:0035435 phosphate ion transmembrane transport(GO:0035435) inorganic anion transmembrane transport(GO:0098661)
2.0 8.2 GO:0015748 organophosphate ester transport(GO:0015748)
1.8 8.9 GO:0016036 cellular response to phosphate starvation(GO:0016036)
1.3 1.3 GO:0010921 regulation of phosphatase activity(GO:0010921)
1.1 3.3 GO:0010350 cellular response to magnesium starvation(GO:0010350)
1.0 2.9 GO:0046391 5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
0.5 2.5 GO:0010043 response to zinc ion(GO:0010043)
0.3 1.0 GO:0055067 regulation of pH(GO:0006885) cellular monovalent inorganic cation homeostasis(GO:0030004) regulation of cellular pH(GO:0030641) pH elevation(GO:0045852) regulation of intracellular pH(GO:0051453) intracellular pH elevation(GO:0051454) monovalent inorganic cation homeostasis(GO:0055067)
0.3 19.3 GO:1903508 positive regulation of transcription, DNA-templated(GO:0045893) positive regulation of RNA metabolic process(GO:0051254) positive regulation of RNA biosynthetic process(GO:1902680) positive regulation of nucleic acid-templated transcription(GO:1903508)
0.1 1.8 GO:0016311 dephosphorylation(GO:0016311)
0.0 0.2 GO:0006096 glycolytic process(GO:0006096)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 8.2 GO:0055052 ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing(GO:0055052)
0.4 2.9 GO:0061695 transferase complex, transferring phosphorus-containing groups(GO:0061695)
0.2 6.0 GO:1904949 ATP-binding cassette (ABC) transporter complex(GO:0043190) ATPase dependent transmembrane transport complex(GO:0098533) ATPase complex(GO:1904949)
0.1 11.1 GO:0042597 periplasmic space(GO:0042597)
0.1 25.4 GO:0005886 plasma membrane(GO:0005886)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
2.8 22.5 GO:1901677 phosphate transmembrane transporter activity(GO:1901677)
1.7 6.8 GO:0016530 metallochaperone activity(GO:0016530)
1.3 3.9 GO:0001098 basal transcription machinery binding(GO:0001098) bacterial-type RNA polymerase holo enzyme binding(GO:0001108)
1.2 10.5 GO:0001140 transcriptional activator activity, bacterial-type RNA polymerase core promoter proximal region sequence-specific binding(GO:0001140)
0.6 5.0 GO:0008194 UDP-glycosyltransferase activity(GO:0008194)
0.5 2.9 GO:0008080 N-acetyltransferase activity(GO:0008080) phosphotransferase activity, phosphate group as acceptor(GO:0016776)
0.4 1.3 GO:0042301 phosphate ion binding(GO:0042301)
0.3 0.6 GO:0009927 histidine phosphotransfer kinase activity(GO:0009927)
0.3 3.8 GO:0001159 bacterial-type RNA polymerase core promoter proximal region sequence-specific DNA binding(GO:0000986) core promoter proximal region sequence-specific DNA binding(GO:0000987) core promoter proximal region DNA binding(GO:0001159)
0.3 1.0 GO:0015181 arginine transmembrane transporter activity(GO:0015181)
0.3 3.3 GO:0004721 phosphorelay sensor kinase activity(GO:0000155) protein histidine kinase activity(GO:0004673) phosphoprotein phosphatase activity(GO:0004721)
0.1 8.0 GO:0003700 transcription factor activity, sequence-specific DNA binding(GO:0003700)
0.1 1.8 GO:0016791 phosphatase activity(GO:0016791)
0.0 0.6 GO:0030145 manganese ion binding(GO:0030145)
0.0 1.1 GO:0005524 ATP binding(GO:0005524)