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GSE55662: Plasticity of transcriptional regulation under antibiotic stress
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Results for NtrC
Z-value: 0.95
Transcription factors associated with NtrC
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| glnG | 0.81 | 1.5e-02 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| nac Show fit | 3.30 |
Nac DNA-binding transcriptional dual regulator |
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| glnK-amtB Show fit | 3.22 |
nitrogen regulatory protein GlnK ammonia / ammonium transporter |
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| glnALG Show fit | 2.72 |
NtrB glutamine synthetase NtrC transcriptional dual regulator |
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| yhdWXYZ Show fit | 2.64 |
putative transport protein, ABC superfamily - periplasmic binding protein putative transport protein, ABC superfamily - membrane component putative transport protein, ABC superfamily - ATP-binding component putative transport protein, ABC superfamily - membrane component |
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| cbl Show fit | 2.52 |
Cbl DNA-binding transcriptional activator |
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| glnLG Show fit | 2.41 |
NtrC transcriptional dual regulator NtrB |
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| patA Show fit | 1.92 |
putrescine aminotransferase |
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| potFGHI Show fit | 1.61 |
putrescine ABC transporter - membrane subunit putrescine ABC transporter - membrane subunit putrescine ABC transporter - ATP binding subunit putrescine ABC transporter - periplasmic binding protein |
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| argT-hisJQMP Show fit | 1.15 |
lysine/arginine/ornithine ABC transporter / histidine ABC transporter - membrane subunit lysine / arginine / ornithine ABC transporter / histidine ABC transporter - ATP binding subunit lysine / arginine / ornithine ABC transporter - periplasmic binding protein lysine / arginine / ornithine ABC transporter / histidine ABC transporter - membrane subunit histidine ABC transporter - periplasmic binding protein |
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| ddpXABCDF Show fit | 0.41 |
D-Ala-D-Ala dipeptidase YddP YddO YddS YddR YddQ |
Network of associatons between targets according to the STRING database.
First level regulatory network of NtrC
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 3.3 | GO:1903508 | positive regulation of transcription, DNA-templated(GO:0045893) positive regulation of RNA metabolic process(GO:0051254) positive regulation of RNA biosynthetic process(GO:1902680) positive regulation of nucleic acid-templated transcription(GO:1903508) |
| 1.1 | 3.2 | GO:0006808 | regulation of nitrogen utilization(GO:0006808) |
| 0.6 | 2.5 | GO:0006791 | sulfur utilization(GO:0006791) |
| 0.1 | 2.4 | GO:0000160 | phosphorelay signal transduction system(GO:0000160) protein autophosphorylation(GO:0046777) |
| 0.5 | 1.9 | GO:0009447 | polyamine catabolic process(GO:0006598) putrescine catabolic process(GO:0009447) |
| 0.5 | 1.6 | GO:0015847 | polyamine transport(GO:0015846) putrescine transport(GO:0015847) |
| 0.3 | 1.2 | GO:0090467 | L-arginine import(GO:0043091) L-amino acid import(GO:0043092) arginine import(GO:0090467) L-arginine import across plasma membrane(GO:0097638) L-arginine import into cell(GO:1902765) L-arginine transmembrane transport(GO:1903400) L-lysine transmembrane transport(GO:1903401) arginine transmembrane transport(GO:1903826) |
| 0.2 | 0.6 | GO:0019740 | nitrogen utilization(GO:0019740) |
| 0.0 | 0.4 | GO:0006024 | aminoglycan biosynthetic process(GO:0006023) glycosaminoglycan biosynthetic process(GO:0006024) peptidoglycan biosynthetic process(GO:0009252) |
| 0.0 | 0.0 | GO:0006527 | succinate metabolic process(GO:0006105) arginine catabolic process(GO:0006527) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 6.5 | GO:0005887 | integral component of plasma membrane(GO:0005887) |
| 0.0 | 4.8 | GO:0005829 | cytosol(GO:0005829) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.4 | 5.1 | GO:0004721 | phosphoprotein phosphatase activity(GO:0004721) |
| 0.0 | 3.3 | GO:0003700 | transcription factor activity, sequence-specific DNA binding(GO:0003700) |
| 0.4 | 3.2 | GO:0008519 | ammonium transmembrane transporter activity(GO:0008519) |
| 0.1 | 2.0 | GO:0008483 | transaminase activity(GO:0008483) |
| 0.4 | 1.2 | GO:0015189 | L-lysine transmembrane transporter activity(GO:0015189) |
| 0.1 | 0.4 | GO:0008235 | metalloexopeptidase activity(GO:0008235) |
| 0.0 | 0.1 | GO:0005350 | monooxygenase activity(GO:0004497) pyrimidine nucleobase transmembrane transporter activity(GO:0005350) |