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GSE55662: Plasticity of transcriptional regulation under antibiotic stress
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Results for NarL
Z-value: 0.43
Transcription factors associated with NarL
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| narL | -0.39 | 3.4e-01 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| dmsABC Show fit | 1.22 |
dimethyl sulfoxide reductase, chain A dimethyl sulfoxide reductase, chain B dimethyl sulfoxide reductase, chain C |
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| ynfEFGH-dmsD Show fit | 1.05 |
putative selenate reductase, predicted Fe-S subunit putative selenate reductase, oxidoreductase subunit putative selenate reductase, oxidoreductase subunit DMS reductase maturation protein putative selenate reductase, predicted membrane anchor subunit |
||
| adhE Show fit | 1.01 |
aldehyde-alcohol dehydrogenase |
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| ompW Show fit | 0.78 |
outer membrane protein W |
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| dcuB-fumB Show fit | 0.69 |
fumarase B dicarboxylate transporter DcuB |
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| hybOABCDEFG Show fit | 0.67 |
hydrogenase 2 accessory protein protein involved with the maturation of hydrogenases 1 and 2 hydrogenase 2-specific chaperone predicted maturation peptidase for hydrogenase 2 hydrogenase 2, large subunit hydrogenase 2 - integral membrane subunit HybB hydrogenase 2 - [Fe-S] binding, ferredoxin-type component HybA hydrogenase 2, small subunit |
||
| nrfABCDEFG Show fit | 0.57 |
activator of formate-dependent nitrite reductase complex NrfG formate dependent nitrite reductase - NrfD subunit formate-dependent nitrite reductase; possible assembly function formate-dependent nitrite reductase - penta-heme cytochrome c formate-dependent nitrite reductase, 4Fe-4S subunit formate dependent nitrite reductase - NrfA subunit |
||
| frdABCD Show fit | 0.55 |
fumarate reductase flavoprotein fumarate reductase iron-sulfur protein fumarate reductase membrane protein fumarate reductase membrane protein |
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| ydhYVWXUT Show fit | 0.36 |
predicted 4Fe-4S ferredoxin-type protein predicted 4Fe-4S ferredoxin-type protein predicted protein predicted oxidoreductase predicted cytochrome conserved protein |
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| hcp-hcr Show fit | 0.32 |
NADH oxidoreductase hybrid-cluster protein |
Network of associatons between targets according to the STRING database.
First level regulatory network of NarL
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 1.2 | GO:0006113 | fermentation(GO:0006113) |
| 0.3 | 1.0 | GO:0006067 | ethanol metabolic process(GO:0006067) |
| 0.1 | 0.8 | GO:0015740 | C4-dicarboxylate transport(GO:0015740) |
| 0.2 | 0.6 | GO:0018063 | protein-heme linkage(GO:0017003) protein-tetrapyrrole linkage(GO:0017006) cytochrome c-heme linkage(GO:0018063) |
| 0.2 | 0.5 | GO:0046210 | nitric oxide metabolic process(GO:0046209) nitric oxide catabolic process(GO:0046210) |
| 0.1 | 0.2 | GO:0030091 | protein repair(GO:0030091) |
| 0.0 | 0.2 | GO:0006531 | aspartate metabolic process(GO:0006531) |
| 0.0 | 0.2 | GO:0010447 | response to acidic pH(GO:0010447) |
| 0.0 | 0.1 | GO:0009437 | carnitine metabolic process(GO:0009437) |
| 0.0 | 0.1 | GO:1902600 | hydrogen ion transmembrane transport(GO:1902600) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 1.9 | GO:0098567 | periplasmic side of plasma membrane(GO:0098567) |
| 0.1 | 1.0 | GO:0031234 | extrinsic component of cytoplasmic side of plasma membrane(GO:0031234) |
| 0.0 | 0.8 | GO:0044462 | cell outer membrane(GO:0009279) external encapsulating structure part(GO:0044462) |
| 0.2 | 0.6 | GO:0045274 | respiratory chain complex II(GO:0045273) plasma membrane respiratory chain complex II(GO:0045274) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.3 | GO:0016667 | oxidoreductase activity, acting on a sulfur group of donors(GO:0016667) |
| 0.1 | 1.0 | GO:0016620 | oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor(GO:0016620) |
| 0.2 | 0.8 | GO:0005469 | succinate:fumarate antiporter activity(GO:0005469) |
| 0.1 | 0.7 | GO:1902670 | carbon dioxide binding(GO:1902670) |
| 0.2 | 0.6 | GO:0016635 | succinate dehydrogenase activity(GO:0000104) oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor(GO:0016635) |
| 0.1 | 0.5 | GO:0016662 | oxidoreductase activity, acting on other nitrogenous compounds as donors, cytochrome as acceptor(GO:0016662) |
| 0.0 | 0.4 | GO:0005506 | iron ion binding(GO:0005506) |
| 0.0 | 0.3 | GO:0016684 | peroxidase activity(GO:0004601) oxidoreductase activity, acting on peroxide as acceptor(GO:0016684) |
| 0.0 | 0.2 | GO:0016841 | ammonia-lyase activity(GO:0016841) |
| 0.0 | 0.2 | GO:0001140 | transcriptional activator activity, bacterial-type RNA polymerase core promoter proximal region sequence-specific binding(GO:0001140) |