ISMARA results: NagC

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GSE55662: Plasticity of transcriptional regulation under antibiotic stress

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Results for NagC

Z-value: 0.90

Transcription factors associated with NagC

Gene Symbol	Gene ID	Gene Info
nagC RegulonDB EcoCyc	nagC	NagC DNA-binding transcriptional dual regulator

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
nagC		0.18	6.7e-01	Click!

Activity profile of NagC motif

Sorted Z-values of NagC motif

Top targets:

Promoter	Log-likelihood	Transcript	Gene	Gene Info
feoABC Show fit	2.99		feoB RegulonDB EcoCyc Show fit feoC RegulonDB EcoCyc Show fit feoA RegulonDB EcoCyc Show fit	Fe²⁺ transporter FeoB predicted DNA-binding transcriptional regulator ferrous iron transport protein A
galP Show fit	2.64		galP RegulonDB EcoCyc Show fit	galactose:H⁺ symporter
ptsHI-crr Show fit	2.28		ptsI RegulonDB EcoCyc Show fit ptsH RegulonDB EcoCyc Show fit crr RegulonDB EcoCyc Show fit	PTS enzyme I HPr Enzyme IIA^Glc; Crr
glmUS Show fit	2.02		glmU RegulonDB EcoCyc Show fit glmS RegulonDB EcoCyc Show fit	fused N-acetylglucosamine-1-phosphate uridyltransferase and glucosamine-1-phosphate acetyltransferase L-glutamine:D-fructose-6-phosphate aminotransferase
manXYZ Show fit	1.68		manX RegulonDB EcoCyc Show fit manY RegulonDB EcoCyc Show fit manZ RegulonDB EcoCyc Show fit	mannose PTS permease - ManX subunit mannose PTS permease - ManY subunit mannose PTS permease - ManZ subunit
dinI Show fit	1.10		dinI RegulonDB EcoCyc Show fit	DNA damage-inducible protein I
fimB Show fit	0.89		fimB RegulonDB EcoCyc Show fit	regulator for fimA
ydeNM Show fit	0.47		ydeM RegulonDB EcoCyc Show fit ydeN RegulonDB EcoCyc Show fit	predicted anaerobic sulfatase maturation enzyme putative sulfatase

Network of associatons between targets according to the STRING database.

First level regulatory network of NagC

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.8	1.7	GO:0015755	fructose transport(GO:0015755)
0.8	2.3	GO:0010906	carbohydrate utilization(GO:0009758) regulation of glucose metabolic process(GO:0010906) regulation of cellular catabolic process(GO:0031329) regulation of cellular carbohydrate catabolic process(GO:0043471) negative regulation of carbohydrate metabolic process(GO:0045912)
0.7	2.6	GO:0015757	galactose transport(GO:0015757)
0.6	1.9	GO:0009226	nucleotide-sugar metabolic process(GO:0009225) nucleotide-sugar biosynthetic process(GO:0009226)
0.6	3.0	GO:0072511	divalent metal ion transport(GO:0070838) divalent inorganic cation transport(GO:0072511)
0.3	0.9	GO:0015074	DNA integration(GO:0015074)
0.1	1.1	GO:0009432	SOS response(GO:0009432)
0.0	0.5	GO:0051604	protein maturation(GO:0051604)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	2.3	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0	4.5	GO:0005886	plasma membrane(GO:0005886)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.7	2.6	GO:0005354	galactose transmembrane transporter activity(GO:0005354)
0.4	2.0	GO:0070569	uridylyltransferase activity(GO:0070569)
0.4	3.0	GO:0005381	iron ion transmembrane transporter activity(GO:0005381)
0.3	2.3	GO:0008047	enzyme activator activity(GO:0008047)
0.3	1.7	GO:0015149	hexose transmembrane transporter activity(GO:0015149)
0.1	1.1	GO:0019899	enzyme binding(GO:0019899)