ISMARA results: Mlc

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GSE55662: Plasticity of transcriptional regulation under antibiotic stress

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Results for Mlc

Z-value: 0.75

Transcription factors associated with Mlc

Gene Symbol	Gene ID	Gene Info
mlc RegulonDB EcoCyc	mlc	Mlc DNA-binding transcriptional repressor
mtfA RegulonDB EcoCyc	mtfA	Mlc titration factor

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
mlc		0.79	1.9e-02	Click!

Activity profile of Mlc motif

Sorted Z-values of Mlc motif

Top targets:

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Promoter	Log-likelihood	Gene	Gene Info
mlc-ynfK Show fit	2.16	mlc RegulonDB EcoCyc Show fit ynfK RegulonDB EcoCyc Show fit	Mlc DNA-binding transcriptional repressor predicted dethiobiotin synthetase
ptsG Show fit	1.34	ptsG RegulonDB EcoCyc Show fit	glucose PTS permease - PtsG subunit
ptsHI-crr Show fit	1.02	ptsI RegulonDB EcoCyc Show fit ptsH RegulonDB EcoCyc Show fit crr RegulonDB EcoCyc Show fit	PTS enzyme I HPr Enzyme IIA^Glc; Crr
mlc Show fit	1.02	mlc RegulonDB EcoCyc Show fit	Mlc DNA-binding transcriptional repressor

Showing 1 to 4 of 4 entries

Network of associatons between targets according to the STRING database.

First level regulatory network of Mlc

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.2	2.2	GO:0006768	biotin metabolic process(GO:0006768) biotin biosynthetic process(GO:0009102)
0.4	1.3	GO:0046323	glucose transport(GO:0015758) glucose import(GO:0046323)
0.3	1.0	GO:0045912	carbohydrate utilization(GO:0009758) regulation of glucose metabolic process(GO:0010906) regulation of cellular catabolic process(GO:0031329) regulation of cellular carbohydrate catabolic process(GO:0043471) negative regulation of carbohydrate metabolic process(GO:0045912)

Showing 1 to 3 of 3 entries

Gene overrepresentation in cellular component category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.1	1.0	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)

Showing 1 to 1 of 1 entries

Gene overrepresentation in molecular function category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.5	2.2	GO:0016882	cyclo-ligase activity(GO:0016882)
0.1	1.3	GO:0090563	protein-phosphocysteine-sugar phosphotransferase activity(GO:0090563)
0.1	1.0	GO:0008047	enzyme activator activity(GO:0008047)

Showing 1 to 3 of 3 entries

Results for Mlc

Z-value: 0.75

Transcription factors associated with Mlc

Activity-expression correlation:

Activity profile of Mlc motif

Sorted Z-values of Mlc motif

Top targets:

Network of associatons between targets according to the STRING database.

First level regulatory network of Mlc

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category: