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GSE55662: Plasticity of transcriptional regulation under antibiotic stress
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Results for Lrp
Z-value: 2.06
Transcription factors associated with Lrp
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| lrp | 0.56 | 1.5e-01 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| ompC Show fit | 12.12 |
outer membrane protein C |
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| ssrS Show fit | 10.68 |
6S RNA |
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| rrsD-ileU-alaU-rrlD-rrfD-thrV-rrfF Show fit | 8.99 |
rrlD 23S ribosomal RNA tRNAileU tRNAalaU tRNAthrV rrfF 5S ribosomal RNA rrsD 16S ribosomal RNA rrfD 5S ribosomal RNA |
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| rrsC-gltU-rrlC-rrfC Show fit | 8.73 |
rrlC 23S ribosomal RNA tRNAgltU rrfC 5S ribosomal RNA rrsC 16S ribosomal RNA |
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| rrsG-gltW-rrlG-rrfG Show fit | 8.31 |
rrlG 23S ribosomal RNA tRNAgltW rrfG 5S ribosomal RNA rrsG 16S ribosomal RNA |
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| rrsE-gltV-rrlE-rrfE Show fit | 8.27 |
rrlE 23S ribosomal RNA tRNAgltV rrsE 16S ribosomal RNA rrfE 5S ribosomal RNA |
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| rrsA-ileT-alaT-rrlA-rrfA Show fit | 7.98 |
23S ribosomal RNA (rrlA) tRNAileT tRNAalaT 16S ribosomal RNA (rrsA) 5S ribosomal RNA (rrfA) |
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| rrsH-ileV-alaV-rrlH-rrfH Show fit | 7.77 |
rrlH 23S ribosomal RNA rrfH 5S ribosomal RNA rrsH 16S ribosomal RNA tRNAileV tRNAalaV |
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| rrsB-gltT-rrlB-rrfB Show fit | 7.74 |
rrlB 23S ribosomal RNA tRNAgltT rrfB 5S ribosomal RNA rrsB 16S ribosomal RNA |
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| lysU Show fit | 6.44 |
lysine-tRNA ligase / Ap4A synthetase / Ap3A synthetase |
Network of associatons between targets according to the STRING database.
First level regulatory network of Lrp
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 3.0 | 12.1 | GO:0015748 | organophosphate ester transport(GO:0015748) |
| 0.3 | 6.4 | GO:0043039 | tRNA aminoacylation for protein translation(GO:0006418) tRNA aminoacylation(GO:0043039) |
| 0.8 | 3.8 | GO:0071468 | cellular response to acidic pH(GO:0071468) |
| 0.9 | 3.5 | GO:0006857 | oligopeptide transport(GO:0006857) oligopeptide transmembrane transport(GO:0035672) |
| 0.7 | 3.5 | GO:0006567 | threonine catabolic process(GO:0006567) |
| 0.9 | 2.6 | GO:0006067 | ethanol metabolic process(GO:0006067) |
| 0.1 | 1.1 | GO:0006972 | hyperosmotic response(GO:0006972) |
| 0.3 | 0.8 | GO:0019676 | ammonia assimilation cycle(GO:0019676) |
| 0.3 | 0.8 | GO:0006544 | glycine metabolic process(GO:0006544) glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464) |
| 0.3 | 0.6 | GO:0006565 | L-serine catabolic process(GO:0006565) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.5 | 12.1 | GO:0045203 | integral component of cell outer membrane(GO:0045203) |
| 0.0 | 0.8 | GO:1990204 | oxidoreductase complex(GO:1990204) |
| 0.0 | 0.5 | GO:1904949 | ATP-binding cassette (ABC) transporter complex(GO:0043190) ATPase dependent transmembrane transport complex(GO:0098533) ATPase complex(GO:1904949) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 6.4 | GO:0016876 | aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876) |
| 1.2 | 3.5 | GO:0035673 | oligopeptide transporter activity(GO:0015198) peptidoglycan transporter activity(GO:0015647) oligopeptide transmembrane transporter activity(GO:0035673) |
| 0.2 | 3.5 | GO:0008198 | ferrous iron binding(GO:0008198) |
| 0.1 | 2.6 | GO:0016616 | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor(GO:0016616) |
| 0.8 | 2.3 | GO:0051087 | chaperone binding(GO:0051087) |
| 0.5 | 1.6 | GO:0051920 | peroxiredoxin activity(GO:0051920) |
| 0.4 | 1.5 | GO:0015491 | L-lysine transmembrane transporter activity(GO:0015189) cation:cation antiporter activity(GO:0015491) |
| 0.1 | 0.8 | GO:0031405 | lipoic acid binding(GO:0031405) |