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GSE55662: Plasticity of transcriptional regulation under antibiotic stress
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Results for IHF
Z-value: 0.50
Transcription factors associated with IHF
Activity-expression correlation:
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| yadV-htrE Show fit | 2.86 |
putative outer membrane usher protein probable pilin chaperone similar to PapD |
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| acs-yjcH-actP Show fit | 1.95 |
acetyl-CoA synthetase (AMP-forming) acetate / glycolate : cation symporter conserved inner membrane protein |
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| dcuD Show fit | 0.81 |
putative transport protein, C4-dicarboxylate uptake C family |
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| ilvLXG_1G_2MEDA Show fit | 0.77 |
branched-chain amino-acid aminotransferase small protein acetolactate synthase / acetohydroxybutanoate synthase, regulatory subunit ilvGEDA operon leader peptide acetolactate synthase II, large subunit, N-ter fragment (pseudogene) dihydroxy acid dehydratase acetolactate synthase II, large subunit, C-ter fragment (pseudogene) threonine deaminase |
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| gcd Show fit | 0.70 |
quinoprotein glucose dehydrogenase |
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| yeiL Show fit | 0.64 |
YeiL DNA-binding transcriptional activator |
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| hycABCDEFGHI Show fit | 0.62 |
hydrogenase 3, membrane subunit hydrogenase 3, large subunit formate hydrogenlyase complex iron-sulfur protein hydrogenase 3 and formate hydrogenlyase complex, HycG subunit regulator of the transcriptional regulator FhlA hydrogenase 3, Fe-S subunit hydrogenase 3, membrane subunit protein required for maturation of hydrogenase 3 hydrogenase 3 maturation protease |
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| sufABCDSE Show fit | 0.61 |
SufB component of SufBCD Fe-S cluster scaffold complex SufC component of SufBCD Fe-S cluster scaffold complex Fe-S transport protein in Fe-S cluster assembly SufD component of SufBCD Fe-S cluster scaffold complex sulfur acceptor for SufS cysteine desulfurase L-cysteine desulfurase |
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| ssuEADCB Show fit | 0.61 |
NADPH-dependent FMN reductase alkanesulfonate monooxygenase, FMNH2-dependent aliphatic sulfonate ABC transporter - periplasmic binding protein aliphatic sulfonate ABC transporter - membrane subunit aliphatic sulfonate ABC transporter - ATP binding subunit |
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| yiaKLMNO-lyxK-sgbHUE Show fit | 0.59 |
L-xylulose kinase 3-keto-L-gulonate 6-phosphate decarboxylase L-ribulose-5-phosphate 4-epimerase predicted L-xylulose 5-phosphate 3-epimerase 2,3-diketo-L-gulonate reductase 2,3-diketo-L-gulonate:Na+ symporter - membrane subunit conserved protein 2,3-diketo-L-gulonate:Na+ symporter - periplasmic binding protein 2,3-diketo-L-gulonate:Na+ symporter - membrane subunit |
Network of associatons between targets according to the STRING database.
First level regulatory network of IHF
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.7 | 3.0 | GO:0043711 | pilus organization(GO:0043711) |
| 0.7 | 2.0 | GO:0018394 | tellurite transport(GO:0015710) peptidyl-lysine acetylation(GO:0018394) post-translational protein modification(GO:0043687) |
| 0.1 | 1.2 | GO:0006970 | response to osmotic stress(GO:0006970) |
| 0.2 | 0.8 | GO:0006549 | isoleucine metabolic process(GO:0006549) isoleucine biosynthetic process(GO:0009097) |
| 0.1 | 0.8 | GO:0015740 | C4-dicarboxylate transport(GO:0015740) |
| 0.2 | 0.7 | GO:0045226 | extracellular polysaccharide biosynthetic process(GO:0045226) extracellular polysaccharide metabolic process(GO:0046379) |
| 0.2 | 0.7 | GO:0006007 | glucose catabolic process(GO:0006007) |
| 0.2 | 0.6 | GO:0042908 | cellular response to sulfate starvation(GO:0009970) xenobiotic transport(GO:0042908) |
| 0.2 | 0.6 | GO:0019324 | L-lyxose metabolic process(GO:0019324) |
| 0.2 | 0.6 | GO:0015886 | heme transport(GO:0015886) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 4.1 | GO:0005887 | integral component of plasma membrane(GO:0005887) |
| 0.1 | 1.2 | GO:0055052 | ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing(GO:0055052) |
| 0.0 | 0.2 | GO:0031246 | intrinsic component of periplasmic side of cell outer membrane(GO:0031246) |
| 0.0 | 0.1 | GO:0045203 | integral component of cell outer membrane(GO:0045203) |
| 0.0 | 0.1 | GO:0042995 | cell projection(GO:0042995) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.7 | 2.0 | GO:0015118 | tellurite transmembrane transporter activity(GO:0015118) tellurite uptake transmembrane transporter activity(GO:0015654) |
| 0.3 | 0.9 | GO:0008742 | L-ribulose-phosphate 4-epimerase activity(GO:0008742) |
| 0.3 | 0.8 | GO:0003984 | acetolactate synthase activity(GO:0003984) |
| 0.2 | 0.7 | GO:0016901 | oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor(GO:0016901) |
| 0.1 | 0.7 | GO:0015114 | phosphate ion transmembrane transporter activity(GO:0015114) |
| 0.2 | 0.6 | GO:0004497 | monooxygenase activity(GO:0004497) |
| 0.2 | 0.6 | GO:0015198 | oligopeptide transporter activity(GO:0015198) oligopeptide transmembrane transporter activity(GO:0035673) |
| 0.1 | 0.6 | GO:0008047 | enzyme activator activity(GO:0008047) |
| 0.0 | 0.6 | GO:0004175 | endopeptidase activity(GO:0004175) |
| 0.1 | 0.5 | GO:0016884 | carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884) |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.4 | REACTOME METABOLISM OF CARBOHYDRATES | Genes involved in Metabolism of carbohydrates |