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GSE55662: Plasticity of transcriptional regulation under antibiotic stress
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Results for FlhDC
Z-value: 1.75
Transcription factors associated with FlhDC
Activity-expression correlation:
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| glpABC Show fit | 7.12 |
anaerobic glycerol-3-phosphate dehydrogenase subunit A anaerobic glycerol-3-phosphate dehydrogenase subunit C anaerobic glycerol-3-phosphate dehydrogenase subunit B |
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| yecR Show fit | 7.08 |
predicted protein |
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| flhBAE Show fit | 6.51 |
flagellar biosynthesis protein FlhB flagellar biosynthesis protein FlhA flagellar protein |
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| fliDST Show fit | 4.81 |
flagellar biosynthesis protein FliT flagellar cap protein FliD; filament capping protein; enables filament assembly flagellar biosynthesis protein FliS |
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| pdeH Show fit | 4.65 |
c-di-GMP phosphodiesterase |
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| flgAMN Show fit | 4.27 |
flagellar biosynthesis; assembly of basal-body periplasmic P ring flagellar biosynthesis protein FlgN anti-sigma factor for FliA (σ28) |
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| flgBCDEFGHIJ Show fit | 3.93 |
flagellar basal-body rod protein FlgC flagellar basal-body rod protein FlgB flagellar basal-body rod protein FlgG flagellar basal-body rod protein FlgF flagellar hook protein FlgE flagellar biosynthesis, initiation of hook assembly FlgJ flagellar P-ring protein FlgI flagellar L-ring protein FlgH; basal-body outer-membrane L (lipopolysaccharide layer) ring protein |
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| flgKL Show fit | 3.11 |
flagellar biosynthesis, hook-filament junction protein 1 flagellar biosynthesis; hook-filament junction protein |
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| fliLMNOPQR Show fit | 2.98 |
flagellar biosynthesis protein FliQ flagellar biosynthesis protein FliP flagellar biosynthesis protein FliR flagellar motor switch protein FliM flagellar protein FliL flagellar biosynthesis protein FliO flagellar motor switch protein FliN |
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| ycgR Show fit | 2.18 |
molecular brake that regulates flagellar motility in response to c-di-GMP |
Network of associatons between targets according to the STRING database.
First level regulatory network of FlhDC
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.2 | 20.9 | GO:0001539 | cilium or flagellum-dependent cell motility(GO:0001539) bacterial-type flagellum-dependent cell motility(GO:0071973) archaeal or bacterial-type flagellum-dependent cell motility(GO:0097588) |
| 1.3 | 10.5 | GO:0044781 | bacterial-type flagellum assembly(GO:0044780) bacterial-type flagellum organization(GO:0044781) |
| 0.7 | 8.7 | GO:0022900 | electron transport chain(GO:0022900) |
| 0.0 | 0.8 | GO:0051604 | protein maturation(GO:0051604) |
| 0.1 | 0.4 | GO:1901998 | toxin transport(GO:1901998) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 3.8 | 19.1 | GO:0009288 | bacterial-type flagellum(GO:0009288) |
| 0.3 | 7.1 | GO:1990204 | oxidoreductase complex(GO:1990204) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 2.4 | 7.1 | GO:0016901 | oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor(GO:0016901) |
| 0.0 | 5.8 | GO:0005515 | protein binding(GO:0005515) |
| 0.9 | 4.7 | GO:0071111 | cyclic-guanylate-specific phosphodiesterase activity(GO:0071111) |
| 0.3 | 2.4 | GO:0016989 | sigma factor antagonist activity(GO:0016989) |
| 0.4 | 2.2 | GO:0030551 | cyclic nucleotide binding(GO:0030551) cyclic-di-GMP binding(GO:0035438) |
| 0.4 | 1.6 | GO:0016662 | oxidoreductase activity, acting on other nitrogenous compounds as donors, cytochrome as acceptor(GO:0016662) |
| 0.2 | 0.8 | GO:0016743 | carboxyl- or carbamoyltransferase activity(GO:0016743) |
| 0.0 | 0.4 | GO:0016597 | amino acid binding(GO:0016597) |