ISMARA results: CytR

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GSE55662: Plasticity of transcriptional regulation under antibiotic stress

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Results for CytR

Z-value: 0.80

Transcription factors associated with CytR

Gene Symbol	Gene ID	Gene Info
cytR RegulonDB EcoCyc	cytR	CytR DNA-binding transcriptional repressor

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
cytR		0.97	5.9e-05	Click!

Activity profile of CytR motif

Sorted Z-values of CytR motif

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Promoter	Log-likelihood	Gene	Gene Info
nupC Show fit	2.09	nupC RegulonDB EcoCyc Show fit	nucleoside:H⁺ symporter NupC
tsx Show fit	2.08	tsx RegulonDB EcoCyc Show fit	nucleoside channel; receptor of phage T6 and colicin K
nupG Show fit	1.92	nupG RegulonDB EcoCyc Show fit	nucleoside:H⁺ symporter NupG
udp Show fit	1.82	udp RegulonDB EcoCyc Show fit	uridine phosphorylase
cytR Show fit	1.77	cytR RegulonDB EcoCyc Show fit	CytR DNA-binding transcriptional repressor
ycdZ Show fit	1.51	ycdZ RegulonDB EcoCyc Show fit	predicted inner membrane protein
cdd Show fit	0.91	cdd RegulonDB EcoCyc Show fit	cytidine deaminase

Showing 1 to 7 of 7 entries

Network of associatons between targets according to the STRING database.

First level regulatory network of CytR

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

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Log-likelihood per target	Total log-likelihood	Term	Description
1.2	6.1	GO:0015858	nucleoside transport(GO:0015858)
0.9	1.8	GO:0034214	protein hexamerization(GO:0034214)
0.0	1.8	GO:1903507	negative regulation of transcription, DNA-templated(GO:0045892) negative regulation of RNA biosynthetic process(GO:1902679) negative regulation of nucleic acid-templated transcription(GO:1903507)
0.2	0.9	GO:0046133	pyrimidine ribonucleoside metabolic process(GO:0046131) pyrimidine ribonucleoside catabolic process(GO:0046133) pyrimidine nucleoside catabolic process(GO:0046135)

Showing 1 to 4 of 4 entries

Gene overrepresentation in cellular component category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.0	4.0	GO:0005887	integral component of plasma membrane(GO:0005887)
0.4	2.1	GO:0046930	pore complex(GO:0046930)

Showing 1 to 2 of 2 entries

Gene overrepresentation in molecular function category:

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Log-likelihood per target	Total log-likelihood	Term	Description
1.2	6.1	GO:0005337	nucleoside transmembrane transporter activity(GO:0005337) nucleobase-containing compound transmembrane transporter activity(GO:0015932)
0.2	1.8	GO:0030955	potassium ion binding(GO:0030955)
0.1	1.8	GO:0000976	transcription regulatory region sequence-specific DNA binding(GO:0000976)
0.1	0.9	GO:0019239	deaminase activity(GO:0019239)

Showing 1 to 4 of 4 entries

Results for CytR

Z-value: 0.80

Transcription factors associated with CytR

Activity-expression correlation:

Activity profile of CytR motif

Sorted Z-values of CytR motif

Top targets:

Network of associatons between targets according to the STRING database.

First level regulatory network of CytR

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category: