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GSE55662: Plasticity of transcriptional regulation under antibiotic stress

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Results for CytR

Z-value: 0.80

Transcription factors associated with CytR

Gene Symbol Gene ID Gene Info
cytR CytR DNA-binding transcriptional repressor

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
cytR0.975.9e-05Click!

Activity profile of CytR motif

Sorted Z-values of CytR motif

Promoter Log-likelihood Transcript Gene Gene Info
nupC 2.09 nucleoside:H+ symporter NupC
tsx 2.08 nucleoside channel; receptor of phage T6 and colicin K
nupG 1.92 nucleoside:H+ symporter NupG
udp 1.82 uridine phosphorylase
cytR 1.77 CytR DNA-binding transcriptional repressor
ycdZ 1.51 predicted inner membrane protein
cdd 0.91 cytidine deaminase

Network of associatons between targets according to the STRING database.

First level regulatory network of CytR

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 6.1 GO:0015858 nucleoside transport(GO:0015858)
0.9 1.8 GO:0034214 protein hexamerization(GO:0034214)
0.2 0.9 GO:0046133 pyrimidine ribonucleoside metabolic process(GO:0046131) pyrimidine ribonucleoside catabolic process(GO:0046133) pyrimidine nucleoside catabolic process(GO:0046135)
0.0 1.8 GO:1903507 negative regulation of transcription, DNA-templated(GO:0045892) negative regulation of RNA biosynthetic process(GO:1902679) negative regulation of nucleic acid-templated transcription(GO:1903507)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.1 GO:0046930 pore complex(GO:0046930)
0.0 4.0 GO:0005887 integral component of plasma membrane(GO:0005887)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 6.1 GO:0005337 nucleoside transmembrane transporter activity(GO:0005337) nucleobase-containing compound transmembrane transporter activity(GO:0015932)
0.2 1.8 GO:0030955 potassium ion binding(GO:0030955)
0.1 0.9 GO:0019239 deaminase activity(GO:0019239)
0.1 1.8 GO:0000976 transcription regulatory region sequence-specific DNA binding(GO:0000976)