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GSE55662: Plasticity of transcriptional regulation under antibiotic stress
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Results for ArgR
Z-value: 2.47
Transcription factors associated with ArgR
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| argR | -0.97 | 4.8e-05 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| artJ Show fit | 13.08 |
L-arginine ABC transporter - periplasmic binding protein |
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| argI Show fit | 10.98 |
ornithine carbamoyltransferase chain I |
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| argG Show fit | 10.03 |
argininosuccinate synthase |
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| carAB Show fit | 9.18 |
carbamoyl phosphate synthetase, β chain carbamoyl phosphate synthetase, α chain |
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| argA Show fit | 8.99 |
N-acetylglutamate synthase |
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| argF Show fit | 4.96 |
ornithine carbamoyltransferase chain F |
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| argCBH Show fit | 3.59 |
argininosuccinate lyase acetylglutamate kinase N-acetylglutamylphosphate reductase |
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| argD Show fit | 3.45 |
N-acetylornithine aminotransferase / N-succinyldiaminopimelate aminotransferase |
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| hisJQMP Show fit | 2.83 |
lysine/arginine/ornithine ABC transporter / histidine ABC transporter - membrane subunit lysine / arginine / ornithine ABC transporter / histidine ABC transporter - ATP binding subunit lysine / arginine / ornithine ABC transporter / histidine ABC transporter - membrane subunit histidine ABC transporter - periplasmic binding protein |
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| astCADBE Show fit | 2.21 |
arginine succinyltransferase succinylarginine dihydrolase succinylornithine transaminase aldehyde dehydrogenase succinylglutamate desuccinylase |
Network of associatons between targets according to the STRING database.
First level regulatory network of ArgR
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 4.2 | 38.0 | GO:0006526 | arginine biosynthetic process(GO:0006526) |
| 3.0 | 12.1 | GO:0090467 | L-arginine import(GO:0043091) L-amino acid import(GO:0043092) arginine import(GO:0090467) L-arginine import across plasma membrane(GO:0097638) L-arginine import into cell(GO:1902765) L-arginine transmembrane transport(GO:1903400) arginine transmembrane transport(GO:1903826) |
| 0.0 | 3.1 | GO:0006974 | cellular response to DNA damage stimulus(GO:0006974) |
| 0.8 | 1.7 | GO:0009084 | glutamine family amino acid biosynthetic process(GO:0009084) |
| 0.4 | 0.9 | GO:1903401 | L-lysine transmembrane transport(GO:1903401) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 13.8 | GO:0030288 | outer membrane-bounded periplasmic space(GO:0030288) |
| 0.0 | 11.8 | GO:0005737 | cytoplasm(GO:0005737) |
| 0.2 | 9.2 | GO:1902494 | catalytic complex(GO:1902494) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.3 | 19.5 | GO:0016597 | amino acid binding(GO:0016597) |
| 4.0 | 15.9 | GO:0016743 | carboxyl- or carbamoyltransferase activity(GO:0016743) |
| 0.4 | 10.0 | GO:0016879 | ligase activity, forming carbon-nitrogen bonds(GO:0016879) |
| 2.3 | 9.2 | GO:0016884 | carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884) |
| 1.5 | 9.0 | GO:0008080 | N-acetyltransferase activity(GO:0008080) |
| 1.4 | 5.7 | GO:0003992 | N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity(GO:0003992) |
| 0.3 | 1.7 | GO:0016638 | oxidoreductase activity, acting on the CH-NH2 group of donors(GO:0016638) |
| 0.4 | 0.9 | GO:0015189 | L-lysine transmembrane transporter activity(GO:0015189) |
| 0.2 | 0.5 | GO:0050897 | cobalt ion binding(GO:0050897) |