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PRJNA438478: RNAseq of wild type zebrafish germline

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Results for klf13+zgc:153115

Z-value: 1.33

Motif logo

Transcription factors associated with klf13+zgc:153115

Gene Symbol Gene ID Gene Info
ENSDARG00000061368 Kruppel-like factor 13
ENSDARG00000069342 153115

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
klf13dr11_v1_chr25_-_34512102_34512102-0.865.0e-06Click!
zgc:153115dr11_v1_chr2_-_7246338_72463380.634.7e-03Click!

Activity profile of klf13+zgc:153115 motif

Sorted Z-values of klf13+zgc:153115 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr16_-_17197546 7.52 ENSDART00000139939
ENSDART00000135146
ENSDART00000063800
ENSDART00000163606
glyceraldehyde-3-phosphate dehydrogenase
chr9_+_8380728 5.27 ENSDART00000133501
si:ch1073-75o15.4
chr5_-_69482891 4.89 ENSDART00000109487

chr10_-_34002185 4.69 ENSDART00000046599
zygote arrest 1-like
chr10_-_44017642 4.50 ENSDART00000135240
ENSDART00000014669
acyl-CoA dehydrogenase short chain
chr4_-_20177868 4.12 ENSDART00000003621
siaz-interacting nuclear protein
chr1_-_34450784 3.72 ENSDART00000140515
LIM domain 7b
chr23_-_31645760 3.70 ENSDART00000035031
serum/glucocorticoid regulated kinase 1
chr7_+_1473929 3.62 ENSDART00000050687
lysophosphatidylcholine acyltransferase 4
chr1_-_34450622 3.50 ENSDART00000083736
LIM domain 7b
chr3_-_40054615 3.45 ENSDART00000003511
ENSDART00000102540
ENSDART00000146121
lethal giant larvae homolog 1 (Drosophila)
chr8_+_47219107 3.20 ENSDART00000146018
ENSDART00000075068
methylenetetrahydrofolate reductase (NAD(P)H)
chr5_+_16117871 3.09 ENSDART00000090657
zinc and ring finger 3
chr14_+_7048930 2.89 ENSDART00000109138
heparin-binding EGF-like growth factor a
chr21_+_34167178 2.70 ENSDART00000158308
transient receptor potential cation channel, subfamily C, member 5b
chr17_-_18898115 2.66 ENSDART00000028044
galactosylceramidase b
chr8_-_2616326 2.58 ENSDART00000027214
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25a
chr23_-_45398622 2.53 ENSDART00000053571
ENSDART00000149464
zgc:100911
chr22_+_835728 2.50 ENSDART00000003325
DENN/MADD domain containing 2Db
chr21_-_32060993 2.44 ENSDART00000131651
si:ch211-160j14.2
chr7_+_38349667 2.39 ENSDART00000010046
rhophilin, Rho GTPase binding protein 2
chr6_+_7414215 2.34 ENSDART00000049339
SRY (sex determining region Y)-box 21a
chr12_+_46634736 2.34 ENSDART00000008009
tripartite motif containing 16
chr11_+_5499661 2.33 ENSDART00000027850
solute carrier family 35, member E1
chr9_+_30421489 2.22 ENSDART00000145025
ENSDART00000132058
zgc:113314
chr15_-_1001177 2.19 ENSDART00000160730
zgc:162936
chr23_+_12160900 2.19 ENSDART00000136046
protein phosphatase 1, regulatory subunit 3Da
chr2_+_59015878 2.18 ENSDART00000148816
ENSDART00000122795
si:ch1073-391i24.1
chr16_+_43077909 2.17 ENSDART00000014140
RUN domain containing 3b
chr22_-_20924747 2.09 ENSDART00000185845
ENSDART00000179672
elongation factor RNA polymerase II
chr9_+_19489304 2.06 ENSDART00000151920
si:ch211-140m22.7
chr25_+_6122823 2.06 ENSDART00000191824
ENSDART00000067514
RNA binding protein with multiple splicing 2a
chr2_-_39675829 2.06 ENSDART00000147821
splA/ryanodine receptor domain and SOCS box containing 4a
chr9_-_19489264 2.05 ENSDART00000122894
WD repeat domain 4
chr10_+_6383270 2.00 ENSDART00000170548
zgc:114200
chr12_+_46869271 1.99 ENSDART00000166560
4-hydroxyphenylpyruvate dioxygenase-like
chr17_-_37795865 1.93 ENSDART00000025853
zinc finger protein 36, C3H type-like 1a
chr8_+_10862353 1.90 ENSDART00000140717
bromodomain and PHD finger containing, 3b
chr25_+_3788443 1.90 ENSDART00000189747
chitinase domain containing 1
chr1_+_604127 1.84 ENSDART00000133165
junctional adhesion molecule 2a
chr14_-_24101897 1.74 ENSDART00000143695
cytoplasmic polyadenylation element binding protein 4a
chr12_-_3053873 1.62 ENSDART00000023796
ENSDART00000137148
dicarbonyl/L-xylulose reductase
chr12_-_3053699 1.61 ENSDART00000139721
dicarbonyl/L-xylulose reductase
chr18_+_7543347 1.60 ENSDART00000103467
ADP-ribosylation factor 5
chr24_-_36238054 1.56 ENSDART00000155725
transmembrane protein 241
chr3_-_52899394 1.54 ENSDART00000128223
coiled-coil-helix-coiled-coil-helix domain containing 5
chr1_-_52201266 1.51 ENSDART00000143805
ENSDART00000023757
RAB3D, member RAS oncogene family, a
chr7_-_32895668 1.46 ENSDART00000141828
anoctamin 5b
chr13_-_42673978 1.46 ENSDART00000133848
ENSDART00000099738
ENSDART00000099729
ENSDART00000169083
leucine rich repeat (in FLII) interacting protein 2
chr12_+_48340133 1.45 ENSDART00000152899
ENSDART00000153335
ENSDART00000054788
DNA-damage-inducible transcript 4
chr20_+_29565906 1.45 ENSDART00000062383
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide a
chr12_-_48312647 1.43 ENSDART00000114415
activating signal cointegrator 1 complex subunit 1
chr23_-_5818992 1.38 ENSDART00000148730
cysteine and glycine-rich protein 1a
chr23_-_10745288 1.38 ENSDART00000140745
ENSDART00000013768
eukaryotic translation initiation factor 4E family member 3
chr10_+_22034477 1.36 ENSDART00000133304
ENSDART00000134189
ENSDART00000021240
ENSDART00000100526
nucleophosmin 1a
chr16_-_17713859 1.36 ENSDART00000149275
zgc:174935
chr20_-_51656512 1.35 ENSDART00000129965

chr2_-_47957673 1.34 ENSDART00000056305
frizzled class receptor 8b
chr19_+_46113828 1.26 ENSDART00000159331
ENSDART00000161826
RNA binding motif protein 24a
chr7_+_29044888 1.26 ENSDART00000086871
glucose-fructose oxidoreductase domain containing 2
chr23_-_17429775 1.24 ENSDART00000043076
pancreatic progenitor cell differentiation and proliferation factor b
chr2_+_43894368 1.19 ENSDART00000143885
guanylate binding protein 3
chr21_+_40685895 1.14 ENSDART00000017709
coiled-coil domain containing 82
chr21_+_6114709 1.13 ENSDART00000065858
folylpolyglutamate synthase
chr10_+_76864 1.13 ENSDART00000036375
Down syndrome critical region 3
chr20_+_23501535 1.09 ENSDART00000177922
ENSDART00000058532
palladin, cytoskeletal associated protein
chr16_+_10329701 1.08 ENSDART00000172845
mediator of DNA damage checkpoint 1
chr6_-_10034145 1.08 ENSDART00000185999
nudix (nucleoside diphosphate linked moiety X)-type motif 15
chr21_+_6197223 1.07 ENSDART00000147716
si:dkey-93m18.3
chr6_-_25165693 1.06 ENSDART00000167259
zinc finger protein 326
chr17_-_51260476 1.06 ENSDART00000084348
trafficking protein particle complex 12
chr10_+_29204581 1.06 ENSDART00000148503
phosphatidylinositol binding clathrin assembly protein a
chr22_-_3182965 1.05 ENSDART00000158009
lon peptidase 1, mitochondrial
chr8_+_104114 1.04 ENSDART00000172101
synuclein, alpha interacting protein
chr25_+_186583 1.03 ENSDART00000161504
PCNA clamp associated factor
chr3_-_50998577 1.02 ENSDART00000157735
CDC42 effector protein (Rho GTPase binding) 4a
chr10_+_21444654 1.02 ENSDART00000140113
ENSDART00000184386
ENSDART00000019252
F-box and WD repeat domain containing 11b
chr22_-_38224315 1.00 ENSDART00000165430
ENSDART00000140968
Hermansky-Pudlak syndrome 3
chr5_+_43458304 0.99 ENSDART00000051114
Rho-related BTB domain containing 2a
chr6_+_23122789 0.97 ENSDART00000049226
ENSDART00000067560
acyl-CoA oxidase 1, palmitoyl
chr15_-_19443997 0.94 ENSDART00000114936
endothelial cell adhesion molecule b
chr18_+_6558338 0.93 ENSDART00000110892
beta-1,4-N-acetyl-galactosaminyl transferase 3b
chr7_+_20260172 0.92 ENSDART00000012450
dishevelled segment polarity protein 2
chr3_-_31924643 0.88 ENSDART00000122589
ring finger protein 113A
chr13_+_21676235 0.87 ENSDART00000137804
ENSDART00000134950
ENSDART00000129653
mitochondrial ribosome-associated GTPase 1
chr5_+_11812089 0.85 ENSDART00000111359
F-box protein 21
chr23_-_18707418 0.84 ENSDART00000144668
ENSDART00000141205
ENSDART00000016765
zgc:103759
chr1_-_493218 0.83 ENSDART00000031635
excision repair cross-complementation group 5
chr23_+_10396842 0.83 ENSDART00000167593
ENSDART00000125103
eukaryotic translation initiation factor 4Ba
chr21_+_6114305 0.79 ENSDART00000141607
folylpolyglutamate synthase
chr21_-_41070182 0.79 ENSDART00000026064
leucyl-tRNA synthetase b
chr1_-_34335752 0.76 ENSDART00000140157
si:dkey-24h22.5
chr20_-_25748407 0.76 ENSDART00000063152
carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 14
chr11_+_13071645 0.75 ENSDART00000162259
zinc finger, FYVE domain containing 9b
chr24_+_35387517 0.75 ENSDART00000058571
snail family zinc finger 2
chr19_+_47290287 0.74 ENSDART00000078382
thiopurine S-methyltransferase, tandem duplicate 1
chr14_+_22172047 0.73 ENSDART00000114750
ENSDART00000148259
gamma-aminobutyric acid (GABA) A receptor, beta 2
chr21_-_11657043 0.71 ENSDART00000141297
calpastatin
chr8_-_40183197 0.71 ENSDART00000005118
glutathione peroxidase 8 (putative)
chr11_+_11152214 0.69 ENSDART00000148030
lymphocyte antigen 75
chr6_+_54576520 0.69 ENSDART00000093199
ENSDART00000127519
ENSDART00000157142
TEA domain family member 3 b
chr18_+_27077853 0.68 ENSDART00000125326
ENSDART00000192660
ENSDART00000098334
protein phosphatase 1, regulatory subunit 15B
chr16_-_26132122 0.67 ENSDART00000157787
lipase, hormone-sensitive b
chr20_+_35058634 0.67 ENSDART00000122696
heterogeneous nuclear ribonucleoprotein Ub
chr5_+_61657702 0.67 ENSDART00000134387
ENSDART00000171248
adaptor-related protein complex 2, beta 1 subunit
chr22_-_6562618 0.66 ENSDART00000106100
zgc:171490
chr23_-_4019699 0.64 ENSDART00000159780
solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8
chr23_-_4019928 0.63 ENSDART00000021062
solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8
chr10_+_3299829 0.62 ENSDART00000183684
zgc:56235
chr21_-_13230925 0.61 ENSDART00000023834
SET nuclear proto-oncogene b
chr19_-_32944050 0.61 ENSDART00000137611
antizyme inhibitor 1b
chr7_+_41146560 0.59 ENSDART00000143285
ENSDART00000173852
ENSDART00000174003
ENSDART00000038487
ENSDART00000173463
ENSDART00000166448
ENSDART00000052274
poly-U binding splicing factor b
chr13_-_36582341 0.59 ENSDART00000137335
lectin, galactoside binding soluble 3a
chr25_-_37284370 0.59 ENSDART00000103222
nudix (nucleoside diphosphate linked moiety X)-type motif 7
chr3_+_17806213 0.58 ENSDART00000055890
zinc finger protein 385C
chr20_-_54564018 0.58 ENSDART00000099832
zgc:153012
chr18_+_18104235 0.57 ENSDART00000145342
cerebellin 1 precursor
chr16_-_7228276 0.57 ENSDART00000149030
5'-nucleotidase, cytosolic IIIA
chr9_+_4378153 0.56 ENSDART00000191264
ENSDART00000182384
kalirin RhoGEF kinase a
chr7_-_73815262 0.56 ENSDART00000185351
zgc:165555
chr24_-_33780387 0.55 ENSDART00000079210
cyclin-dependent kinase 5
chr13_-_44808783 0.54 ENSDART00000099984
glyoxalase 1
chr7_-_5396154 0.53 ENSDART00000172980
Rho guanine nucleotide exchange factor (GEF) 11
chr2_-_3614005 0.52 ENSDART00000110399
phosphotriesterase related
chr18_+_6558146 0.51 ENSDART00000169401
beta-1,4-N-acetyl-galactosaminyl transferase 3b
chr21_+_37436907 0.51 ENSDART00000182611
ENSDART00000076328
progesterone receptor membrane component 1
chr14_+_6963312 0.49 ENSDART00000150050
heterogeneous nuclear ribonucleoprotein A/Ba
chr16_+_39271123 0.47 ENSDART00000043823
ENSDART00000141801
oxysterol binding protein-like 10b
chr5_+_68807170 0.46 ENSDART00000017849
hairy and enhancer of split related-7
chr1_+_7189856 0.46 ENSDART00000092114
si:ch73-383l1.1
chr19_-_2421793 0.45 ENSDART00000180238
transmembrane protein 196
chr25_-_4235037 0.44 ENSDART00000093003
synaptotagmin VIIa
chr21_-_13231101 0.43 ENSDART00000190943
SET nuclear proto-oncogene b
chr11_+_34921492 0.40 ENSDART00000128070
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2a
chr25_+_35913614 0.39 ENSDART00000022437
glucose-6-phosphate isomerase a
chr7_+_4474880 0.38 ENSDART00000143528
si:dkey-83f18.14
chr22_+_1421212 0.37 ENSDART00000161813
zgc:101130
chr3_+_17951790 0.37 ENSDART00000164663
ATP citrate lyase a
chr24_-_37688398 0.37 ENSDART00000141414
zgc:112185
chr1_-_55196103 0.36 ENSDART00000140153
methylthioribose-1-phosphate isomerase 1
chr4_-_5455506 0.36 ENSDART00000156593
ENSDART00000154676
si:dkey-14d8.22
chr3_+_31925067 0.36 ENSDART00000127330
ENSDART00000055279
small nuclear ribonucleoprotein 70 (U1)
chr9_-_28399071 0.35 ENSDART00000104317
ENSDART00000064343
Kruppel-like factor 7b
chr19_+_29854223 0.35 ENSDART00000109729
ENSDART00000157419
si:ch73-130a3.4
chr21_+_15704556 0.34 ENSDART00000024858
ENSDART00000146909
coiled-coil-helix-coiled-coil-helix domain containing 10
chr3_-_47876427 0.34 ENSDART00000180844
ENSDART00000124480
adhesion G protein-coupled receptor L1a
chr7_+_69528850 0.33 ENSDART00000109507
Rap1 GTPase-GDP dissociation stimulator 1
chr25_+_25123385 0.33 ENSDART00000163892
lactate dehydrogenase A4
chr21_+_45386033 0.32 ENSDART00000151773
jade family PHD finger 2
chr17_+_6765621 0.30 ENSDART00000156637
ENSDART00000007622
AFG1 like ATPase a
chr3_+_726000 0.30 ENSDART00000158510
diverse immunoglobulin domain-containing protein 1.17
chr3_+_62327332 0.28 ENSDART00000158414

chr7_-_73846995 0.27 ENSDART00000188079

chr24_+_17005647 0.26 ENSDART00000149149
zinc finger protein, X-linked
chr23_+_30006206 0.26 ENSDART00000150153
tumor necrosis factor receptor superfamily, member 9a
chr10_+_44940693 0.25 ENSDART00000157515
cyclin and CBS domain divalent metal cation transport mediator 4a
chr15_-_9031996 0.25 ENSDART00000124998
reticulon 2a
chr12_-_22670279 0.25 ENSDART00000164888
zinc finger, CCHC domain containing 4
chr7_-_18601206 0.24 ENSDART00000111636
si:ch211-119e14.2
chr11_-_36341028 0.23 ENSDART00000146093
sortilin 1a
chr7_+_58730201 0.23 ENSDART00000073640
pleiomorphic adenoma gene 1
chr22_+_2217939 0.22 ENSDART00000145394
ENSDART00000146694
zinc finger protein 1172
chr7_+_9880811 0.22 ENSDART00000128376
lines homolog 1
chr22_-_27622854 0.22 ENSDART00000190874

chr22_-_6968756 0.22 ENSDART00000136636
fibroblast growth factor receptor 1b, like
chr12_-_4540564 0.21 ENSDART00000106566

chr19_-_205104 0.19 ENSDART00000011890
zinc finger and BTB domain containing 22a
chr8_-_21268303 0.19 ENSDART00000067211
G protein-coupled receptor 37 like 1b
chr3_-_33934788 0.19 ENSDART00000151411
general transcription factor IIF, polypeptide 1
chr1_+_56755536 0.19 ENSDART00000157727

chr4_-_39448829 0.19 ENSDART00000168526
si:dkey-261o4.9
chr12_+_11080776 0.18 ENSDART00000079336
retinoic acid receptor, alpha a
chr10_+_10728870 0.18 ENSDART00000109282
SWI5 homologous recombination repair protein
chr25_-_18730697 0.17 ENSDART00000182475
si:dkeyp-93a5.2
chr12_+_6391243 0.17 ENSDART00000152765
protein kinase, cGMP-dependent, type Ib
chr15_-_3078600 0.17 ENSDART00000172842
fibronectin type III domain containing 3A
chr23_-_790620 0.17 ENSDART00000166818

chr9_-_37749973 0.17 ENSDART00000087663
sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5Ba
chr21_+_28535203 0.16 ENSDART00000184950

chr21_+_43854594 0.16 ENSDART00000142718
colony stimulating factor 1 receptor, b
chr6_-_54111928 0.15 ENSDART00000083880
hyaluronoglucosaminidase 2a
chr4_+_14957360 0.14 ENSDART00000002770
ENSDART00000111882
ENSDART00000148292
tetraspanin 33a
chr18_+_41549764 0.14 ENSDART00000059135
BCL tumor suppressor 7Bb
chr1_-_57839070 0.12 ENSDART00000152571
si:dkey-1c7.3
chr25_-_20268027 0.12 ENSDART00000138763
DnaJ (Hsp40) homolog, subfamily B, member 9a
chr16_-_24561354 0.12 ENSDART00000193278
ENSDART00000126274
si:ch211-79k12.2
chr18_+_40584288 0.11 ENSDART00000087692
si:ch211-132b12.3
chr21_+_1382078 0.11 ENSDART00000188463
transcription factor 4
chr3_+_59117136 0.10 ENSDART00000182745
mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase, isozyme B
chr15_-_5563551 0.10 ENSDART00000099520
ATG16 autophagy related 16-like 2 (S. cerevisiae)
chr19_+_22727940 0.10 ENSDART00000052509
thyrotropin-releasing hormone receptor b
chr11_-_4235811 0.09 ENSDART00000121716
si:ch211-236d3.4
chr20_+_572037 0.09 ENSDART00000028062
ENSDART00000152736
ENSDART00000031759
ENSDART00000162198
SET and MYND domain containing 2b
chr22_-_16275236 0.08 ENSDART00000149051
cell division cycle 14Ab
chr10_+_38643304 0.07 ENSDART00000067447
matrix metallopeptidase 30
chr9_-_1984604 0.07 ENSDART00000082339
homeobox D12a
chr19_+_46237665 0.06 ENSDART00000159391
vacuolar protein sorting 28 (yeast)
chr18_-_6943577 0.06 ENSDART00000132399
si:dkey-266m15.6
chr20_+_46311242 0.06 ENSDART00000038696
feline leukemia virus subgroup C cellular receptor family, member 2b
chr10_+_1899595 0.04 ENSDART00000040271

Network of associatons between targets according to the STRING database.

First level regulatory network of klf13+zgc:153115

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 4.5 GO:0019626 short-chain fatty acid catabolic process(GO:0019626)
1.1 3.2 GO:0005997 xylulose metabolic process(GO:0005997)
0.8 3.1 GO:0032801 receptor catabolic process(GO:0032801)
0.5 2.1 GO:0036265 RNA (guanine-N7)-methylation(GO:0036265)
0.5 1.9 GO:0046900 tetrahydrofolylpolyglutamate metabolic process(GO:0046900)
0.4 1.3 GO:2001014 skeletal muscle fiber differentiation(GO:0098528) regulation of skeletal muscle cell differentiation(GO:2001014)
0.4 2.1 GO:0051148 smooth muscle cell differentiation(GO:0051145) negative regulation of muscle cell differentiation(GO:0051148)
0.3 2.1 GO:0042795 snRNA transcription from RNA polymerase II promoter(GO:0042795)
0.3 2.7 GO:0046477 glycosylceramide catabolic process(GO:0046477)
0.3 2.9 GO:2000273 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741) positive regulation of receptor activity(GO:2000273)
0.3 4.1 GO:0001840 neural plate development(GO:0001840)
0.3 0.8 GO:0006295 nucleotide-excision repair, DNA incision, 3'-to lesion(GO:0006295)
0.3 3.4 GO:0032878 regulation of establishment or maintenance of cell polarity(GO:0032878)
0.2 1.7 GO:0002931 response to ischemia(GO:0002931)
0.2 1.0 GO:0033540 fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540)
0.2 3.6 GO:0009086 methionine biosynthetic process(GO:0009086)
0.2 2.0 GO:0007220 Notch receptor processing(GO:0007220)
0.2 7.5 GO:0050821 protein stabilization(GO:0050821)
0.2 0.5 GO:1903537 meiotic cell cycle process involved in oocyte maturation(GO:1903537) regulation of meiotic cell cycle process involved in oocyte maturation(GO:1903538)
0.2 0.7 GO:0032211 negative regulation of telomere maintenance via telomerase(GO:0032211) negative regulation of telomere maintenance via telomere lengthening(GO:1904357)
0.2 1.4 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.1 1.7 GO:0016074 snoRNA metabolic process(GO:0016074)
0.1 1.1 GO:0009146 dGTP catabolic process(GO:0006203) purine nucleoside triphosphate catabolic process(GO:0009146) purine deoxyribonucleoside triphosphate catabolic process(GO:0009217) dGTP metabolic process(GO:0046070)
0.1 0.9 GO:0090179 establishment of planar polarity of embryonic epithelium(GO:0042249) establishment of planar polarity involved in neural tube closure(GO:0090177) regulation of establishment of planar polarity involved in neural tube closure(GO:0090178) planar cell polarity pathway involved in neural tube closure(GO:0090179)
0.1 0.8 GO:0050655 dermatan sulfate proteoglycan metabolic process(GO:0050655)
0.1 0.8 GO:0097010 eukaryotic translation initiation factor 4F complex assembly(GO:0097010)
0.1 0.6 GO:0072677 eosinophil chemotaxis(GO:0048245) eosinophil migration(GO:0072677)
0.1 0.9 GO:0021634 optic nerve formation(GO:0021634)
0.1 1.0 GO:0031272 pseudopodium organization(GO:0031268) pseudopodium assembly(GO:0031269) regulation of pseudopodium assembly(GO:0031272) positive regulation of pseudopodium assembly(GO:0031274)
0.1 0.6 GO:1902267 polyamine transport(GO:0015846) polyamine transmembrane transport(GO:1902047) regulation of polyamine transmembrane transport(GO:1902267) positive regulation of polyamine transmembrane transport(GO:1902269)
0.1 0.7 GO:0097340 inhibition of cysteine-type endopeptidase activity(GO:0097340) zymogen inhibition(GO:0097341)
0.1 2.7 GO:0006828 manganese ion transport(GO:0006828)
0.1 2.2 GO:0010962 regulation of glycogen biosynthetic process(GO:0005979) regulation of glucan biosynthetic process(GO:0010962)
0.1 1.4 GO:0061055 myotome development(GO:0061055)
0.1 1.8 GO:0007520 myoblast fusion(GO:0007520)
0.1 1.1 GO:0051131 chaperone-mediated protein complex assembly(GO:0051131)
0.1 0.6 GO:0009109 coenzyme catabolic process(GO:0009109)
0.1 1.0 GO:0019985 translesion synthesis(GO:0019985)
0.1 2.0 GO:0009072 aromatic amino acid family metabolic process(GO:0009072)
0.1 0.7 GO:0035306 positive regulation of dephosphorylation(GO:0035306) positive regulation of protein dephosphorylation(GO:0035307)
0.0 0.7 GO:0019433 triglyceride catabolic process(GO:0019433)
0.0 0.2 GO:0042481 regulation of odontogenesis(GO:0042481)
0.0 0.4 GO:0035588 adenosine receptor signaling pathway(GO:0001973) purinergic receptor signaling pathway(GO:0035587) G-protein coupled purinergic receptor signaling pathway(GO:0035588)
0.0 0.3 GO:0043982 histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)
0.0 1.1 GO:0016185 synaptic vesicle budding from presynaptic endocytic zone membrane(GO:0016185)
0.0 1.5 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.0 1.5 GO:0032007 negative regulation of TOR signaling(GO:0032007)
0.0 0.8 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0 1.0 GO:0043652 engulfment of apoptotic cell(GO:0043652)
0.0 0.2 GO:0006895 Golgi to endosome transport(GO:0006895)
0.0 1.3 GO:0032784 regulation of DNA-templated transcription, elongation(GO:0032784)
0.0 0.4 GO:0006085 acetyl-CoA biosynthetic process(GO:0006085)
0.0 0.7 GO:0035329 hippo signaling(GO:0035329)
0.0 0.3 GO:0010960 magnesium ion homeostasis(GO:0010960)
0.0 4.1 GO:0001947 heart looping(GO:0001947)
0.0 1.4 GO:0045214 sarcomere organization(GO:0045214)
0.0 1.3 GO:0051453 regulation of intracellular pH(GO:0051453)
0.0 2.3 GO:0048545 response to steroid hormone(GO:0048545)
0.0 0.1 GO:0019079 viral genome replication(GO:0019079) negative stranded viral RNA replication(GO:0039689) viral RNA genome replication(GO:0039694) RNA replication(GO:0039703) multi-organism biosynthetic process(GO:0044034)
0.0 3.7 GO:0018105 peptidyl-serine phosphorylation(GO:0018105)
0.0 0.4 GO:0051156 glucose 6-phosphate metabolic process(GO:0051156)
0.0 1.5 GO:1902476 chloride transmembrane transport(GO:1902476)
0.0 1.6 GO:0006334 nucleosome assembly(GO:0006334)
0.0 0.2 GO:0050975 sensory perception of touch(GO:0050975)
0.0 0.2 GO:0031167 rRNA methylation(GO:0031167)
0.0 0.6 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 0.5 GO:0030038 contractile actin filament bundle assembly(GO:0030038) stress fiber assembly(GO:0043149)
0.0 0.1 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.0 0.2 GO:1902017 regulation of cilium assembly(GO:1902017)
0.0 1.4 GO:0006413 translational initiation(GO:0006413)
0.0 0.2 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.0 0.3 GO:0014866 skeletal myofibril assembly(GO:0014866)
0.0 4.7 GO:0006412 translation(GO:0006412)
0.0 0.3 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.1 GO:0043527 tRNA methyltransferase complex(GO:0043527)
0.3 1.1 GO:0044609 DBIRD complex(GO:0044609)
0.2 2.0 GO:0070765 gamma-secretase complex(GO:0070765)
0.2 1.4 GO:0005845 mRNA cap binding complex(GO:0005845)
0.2 2.9 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.2 0.7 GO:1990498 mitotic spindle microtubule(GO:1990498)
0.1 1.7 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.1 1.1 GO:0098894 presynaptic endocytic zone(GO:0098833) presynaptic endocytic zone membrane(GO:0098835) extrinsic component of presynaptic membrane(GO:0098888) extrinsic component of presynaptic endocytic zone(GO:0098894)
0.1 3.4 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.1 0.6 GO:0001772 immunological synapse(GO:0001772)
0.1 1.1 GO:0030008 TRAPP complex(GO:0030008)
0.0 0.8 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 1.8 GO:0098636 protein complex involved in cell adhesion(GO:0098636)
0.0 2.1 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 1.7 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 0.2 GO:0005674 transcription factor TFIIF complex(GO:0005674)
0.0 0.6 GO:0046930 pore complex(GO:0046930)
0.0 2.0 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.7 GO:0030131 clathrin adaptor complex(GO:0030131)
0.0 0.2 GO:0033061 DNA recombinase mediator complex(GO:0033061)
0.0 0.5 GO:0009925 basal plasma membrane(GO:0009925)
0.0 1.2 GO:0005684 U2-type spliceosomal complex(GO:0005684)
0.0 4.6 GO:0005764 lysosome(GO:0005764)
0.0 0.7 GO:0005901 caveola(GO:0005901) plasma membrane raft(GO:0044853)
0.0 1.4 GO:0030018 Z disc(GO:0030018)
0.0 2.7 GO:0034703 cation channel complex(GO:0034703)
0.0 0.1 GO:1902636 kinociliary basal body(GO:1902636)
0.0 2.0 GO:0008021 synaptic vesicle(GO:0008021)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.9 7.5 GO:0043891 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.7 2.0 GO:0003868 4-hydroxyphenylpyruvate dioxygenase activity(GO:0003868)
0.4 1.3 GO:1990715 mRNA CDS binding(GO:1990715) sequence-specific mRNA binding(GO:1990825)
0.4 1.5 GO:0071889 14-3-3 protein binding(GO:0071889)
0.3 4.5 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.3 1.4 GO:0033842 N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase activity(GO:0033842)
0.3 0.8 GO:1990174 phosphodiesterase decapping endonuclease activity(GO:1990174)
0.2 1.0 GO:0003997 acyl-CoA oxidase activity(GO:0003997)
0.2 3.3 GO:0045159 myosin II binding(GO:0045159)
0.2 1.1 GO:0047429 nucleoside-triphosphate diphosphatase activity(GO:0047429)
0.2 0.5 GO:0008119 thiopurine S-methyltransferase activity(GO:0008119)
0.1 2.2 GO:2001069 glycogen binding(GO:2001069)
0.1 0.9 GO:0001091 RNA polymerase II basal transcription factor binding(GO:0001091)
0.1 3.4 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.1 1.9 GO:0008061 chitin binding(GO:0008061)
0.1 0.6 GO:0015288 porin activity(GO:0015288)
0.1 0.8 GO:0033592 RNA strand annealing activity(GO:0033592) RNA strand-exchange activity(GO:0034057)
0.1 0.6 GO:0019865 IgE binding(GO:0019863) immunoglobulin binding(GO:0019865)
0.1 2.7 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.1 1.1 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.1 1.3 GO:0015385 monovalent cation:proton antiporter activity(GO:0005451) sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.1 3.2 GO:0016646 oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor(GO:0016646)
0.1 2.1 GO:0016423 tRNA (guanine) methyltransferase activity(GO:0016423)
0.1 1.7 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.1 0.6 GO:0042978 ornithine decarboxylase activator activity(GO:0042978)
0.1 0.7 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.1 3.7 GO:0015459 potassium channel regulator activity(GO:0015459)
0.1 1.4 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.1 0.7 GO:0033878 hormone-sensitive lipase activity(GO:0033878)
0.1 1.1 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.1 0.5 GO:0035173 histone kinase activity(GO:0035173)
0.1 1.9 GO:0016881 acid-amino acid ligase activity(GO:0016881)
0.1 0.8 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.1 1.4 GO:0042805 actinin binding(GO:0042805)
0.1 1.2 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 2.6 GO:0005347 ATP transmembrane transporter activity(GO:0005347)
0.0 0.3 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.0 2.1 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.4 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.0 0.4 GO:0030619 U1 snRNA binding(GO:0030619)
0.0 0.5 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.2 GO:0033906 hyaluronoglucuronidase activity(GO:0033906)
0.0 0.5 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.0 0.7 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 2.9 GO:0015297 antiporter activity(GO:0015297)
0.0 0.2 GO:0016433 rRNA (adenine) methyltransferase activity(GO:0016433)
0.0 0.2 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.0 2.0 GO:0030674 protein binding, bridging(GO:0030674)
0.0 0.6 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 0.6 GO:0016289 CoA hydrolase activity(GO:0016289)
0.0 0.9 GO:0005109 frizzled binding(GO:0005109)
0.0 2.7 GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds(GO:0004553)
0.0 6.7 GO:0044822 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.0 5.1 GO:0030246 carbohydrate binding(GO:0030246)
0.0 0.5 GO:0015248 sterol transporter activity(GO:0015248)
0.0 0.1 GO:0004997 thyrotropin-releasing hormone receptor activity(GO:0004997)
0.0 1.5 GO:0005254 chloride channel activity(GO:0005254)
0.0 1.1 GO:0030276 clathrin binding(GO:0030276)
0.0 0.8 GO:0004520 endodeoxyribonuclease activity(GO:0004520)
0.0 0.4 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.0 0.3 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 2.4 GO:0046982 protein heterodimerization activity(GO:0046982)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 7.9 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.1 5.3 PID PI3KCI PATHWAY Class I PI3K signaling events
0.1 0.9 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.1 1.0 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.0 1.2 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 0.5 PID EPHA FWDPATHWAY EPHA forward signaling
0.0 0.7 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 0.5 ST GA13 PATHWAY G alpha 13 Pathway
0.0 1.5 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.0 0.3 PID RAC1 REG PATHWAY Regulation of RAC1 activity

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 3.6 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.4 7.5 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.3 4.5 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.1 1.0 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.1 5.1 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.1 2.3 REACTOME ELONGATION ARREST AND RECOVERY Genes involved in Elongation arrest and recovery
0.1 0.7 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.0 0.7 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.0 0.9 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.5 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.8 REACTOME FORMATION OF TRANSCRIPTION COUPLED NER TC NER REPAIR COMPLEX Genes involved in Formation of transcription-coupled NER (TC-NER) repair complex
0.0 0.5 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 0.4 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 0.8 REACTOME CHONDROITIN SULFATE DERMATAN SULFATE METABOLISM Genes involved in Chondroitin sulfate/dermatan sulfate metabolism
0.0 1.1 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0 1.3 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 0.3 REACTOME PYRUVATE METABOLISM Genes involved in Pyruvate metabolism
0.0 0.2 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus