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PRJNA438478: RNAseq of wild type zebrafish germline

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Results for foxf1+foxf2a+foxf2b

Z-value: 1.42

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Transcription factors associated with foxf1+foxf2a+foxf2b

Gene Symbol Gene ID Gene Info
ENSDARG00000015399 forkhead box F1
ENSDARG00000017195 forkhead box F2a
ENSDARG00000070389 forkhead box F2b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
foxf2bdr11_v1_chr20_+_26690036_26690036-0.351.5e-01Click!
foxf2adr11_v1_chr2_-_716426_7164260.243.3e-01Click!
foxf1dr11_v1_chr18_+_30847237_308472370.214.0e-01Click!

Activity profile of foxf1+foxf2a+foxf2b motif

Sorted Z-values of foxf1+foxf2a+foxf2b motif

Promoter Log-likelihood Transcript Gene Gene Info
chr22_+_11756040 2.75 ENSDART00000105808
keratin 97
chr4_-_1720648 1.89 ENSDART00000103484
growth arrest-specific 2 like 3
chr13_+_22675802 1.88 ENSDART00000145538
ENSDART00000143312
zgc:193505
chr11_-_30508843 1.53 ENSDART00000101667
ENSDART00000179930
mitogen-activated protein kinase kinase kinase kinase 3a
chr23_-_33558161 1.52 ENSDART00000018301
integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
chr1_-_6028876 1.50 ENSDART00000168117
si:ch1073-345a8.1
chr1_-_50611031 1.46 ENSDART00000148285
protein phosphatase, Mg2+/Mn2+ dependent, 1K
chr8_-_53044300 1.41 ENSDART00000191653
nuclear receptor subfamily 6, group A, member 1a
chr1_+_496268 1.40 ENSDART00000109415
basic leucine zipper nuclear factor 1
chr2_+_27652386 1.36 ENSDART00000188261
transmembrane protein 68
chr4_-_6373735 1.35 ENSDART00000140100
si:ch73-156e19.1
chr2_+_44512324 1.35 ENSDART00000155017
ENSDART00000156310
ENSDART00000156686
PAS domain containing serine/threonine kinase
chr19_+_43669122 1.30 ENSDART00000139151
si:ch211-193k19.1
chr24_-_17023392 1.28 ENSDART00000106058
prostaglandin D2 synthase b, tandem duplicate 2
chr1_+_51386649 1.27 ENSDART00000152289
autophagy related 4D, cysteine peptidase a
chr5_-_3960161 1.24 ENSDART00000111453
myosin XIX
chr9_+_41459759 1.22 ENSDART00000132501
ENSDART00000100265
nuclear envelope integral membrane protein 2
chr2_+_27651984 1.22 ENSDART00000126762
transmembrane protein 68
chr1_-_43920371 1.21 ENSDART00000109283
secretory calcium-binding phosphoprotein 7
chr8_-_33154677 1.20 ENSDART00000133300
zinc finger and BTB domain containing 34
chr1_+_45969240 1.18 ENSDART00000042086
Rho guanine nucleotide exchange factor (GEF) 7b
chr8_-_39859688 1.13 ENSDART00000019907
unc-119 homolog 1
chr3_+_24511959 1.11 ENSDART00000133898
dynein, axonemal, light chain 4a
chr11_+_24046179 1.09 ENSDART00000006703
MAF1 homolog, negative regulator of RNA polymerase III
chr8_+_49092077 1.08 ENSDART00000032355
zgc:56525
chr15_-_33807758 1.08 ENSDART00000158445
PDS5 cohesin associated factor B
chr6_+_2174082 1.06 ENSDART00000073936
activin A receptor type 1Bb
chr3_-_4501026 1.05 ENSDART00000163052
zgc:162198
chr6_+_22104857 1.04 ENSDART00000129202
si:dkey-156n14.5
chr11_-_11890001 1.02 ENSDART00000081544
WAS/WASL interacting protein family, member 2a
chr8_+_29636431 1.00 ENSDART00000133047
SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1 a
chr23_-_22523303 1.00 ENSDART00000079019
splA/ryanodine receptor domain and SOCS box containing 1
chr19_+_25971000 1.00 ENSDART00000089836
jumonji, AT rich interactive domain 2b
chr22_+_12361317 1.00 ENSDART00000189963
ENSDART00000159614
R3H domain containing 1
chr7_-_60351537 0.99 ENSDART00000159875
phospholipase C, beta 3 (phosphatidylinositol-specific)
chr15_-_29354020 0.98 ENSDART00000127795
tsukushi small leucine rich proteoglycan homolog (Xenopus laevis)
chr16_+_18535618 0.98 ENSDART00000021596
retinoid x receptor, beta b
chr7_-_53117131 0.98 ENSDART00000169211
ENSDART00000168890
ENSDART00000172179
ENSDART00000167882
cadherin 1, type 1, E-cadherin (epithelial)
chr8_-_53044089 0.98 ENSDART00000135982
nuclear receptor subfamily 6, group A, member 1a
chr18_-_44847855 0.97 ENSDART00000086823
signal recognition particle receptor (docking protein)
chr6_+_23809501 0.97 ENSDART00000168701
glutamate-ammonia ligase (glutamine synthase) b
chr15_+_19990068 0.96 ENSDART00000154033
ENSDART00000054428
zgc:112083
chr2_+_1988036 0.95 ENSDART00000155956
synovial sarcoma, X breakpoint 2 interacting protein a
chr6_+_20954400 0.95 ENSDART00000143248
ENSDART00000165806
serine/threonine kinase 11 interacting protein
chr7_+_13830052 0.94 ENSDART00000191360
abhydrolase domain containing 2a
chr7_+_24889783 0.94 ENSDART00000005329
ENSDART00000159955
MAP/microtubule affinity-regulating kinase 2b
chr15_+_23657051 0.93 ENSDART00000078336
kinesin light chain 3
chr1_+_19538299 0.93 ENSDART00000109416
structural maintenance of chromosomes 2
chr6_+_4255319 0.93 ENSDART00000170351
neurobeachin-like 1
chr8_+_23147218 0.93 ENSDART00000030920
ENSDART00000141175
ENSDART00000146264
GID complex subunit 8 homolog a (S. cerevisiae)
chr7_-_60351876 0.92 ENSDART00000098563
phospholipase C, beta 3 (phosphatidylinositol-specific)
chr24_+_17068724 0.92 ENSDART00000191137
phosphatidylinositol-5-phosphate 4-kinase, type II, alpha a
chr21_+_25802190 0.92 ENSDART00000128987
neurofibromin 2b (merlin)
chr11_+_18612421 0.91 ENSDART00000110621
nuclear receptor coactivator 3
chr12_-_18961491 0.91 ENSDART00000172574
E1A binding protein p300 a
chr15_+_44283723 0.91 ENSDART00000167722
CWF19-like 2, cell cycle control (S. pombe)
chr20_+_34390196 0.90 ENSDART00000183596
tRNA methyltransferase 1-like
chr13_-_12667220 0.90 ENSDART00000079594
family with sequence similarity 241 member A
chr21_-_25295087 0.90 ENSDART00000087910
ENSDART00000147860
suppression of tumorigenicity 14 (colon carcinoma) b
chr24_+_17069420 0.89 ENSDART00000014787
phosphatidylinositol-5-phosphate 4-kinase, type II, alpha a
chr7_-_13906409 0.89 ENSDART00000062257
solute carrier family 39 (zinc transporter), member 1
chr12_+_27096835 0.87 ENSDART00000149475
tubulin tyrosine ligase-like family, member 6
chr14_-_21660548 0.87 ENSDART00000161713
ENSDART00000089845
lysine (K)-specific demethylase 3B
chr2_+_31437547 0.87 ENSDART00000141170
signal transducing adaptor molecule (SH3 domain and ITAM motif) 1
chr23_-_18017946 0.86 ENSDART00000104592
peptidase M20 domain containing 1, tandem duplicate 2
chr9_+_22780901 0.86 ENSDART00000110992
ENSDART00000143972
replication timing regulatory factor 1
chr1_+_26676758 0.85 ENSDART00000152299
si:dkey-25o16.4
chr1_-_43920576 0.85 ENSDART00000191914
secretory calcium-binding phosphoprotein 7
chr22_+_30195257 0.85 ENSDART00000027803
ENSDART00000172496
adducin 3 (gamma) a
chr23_+_27778670 0.84 ENSDART00000053863
lysine (K)-specific methyltransferase 2D
chr6_-_37745508 0.84 ENSDART00000078316
non imprinted in Prader-Willi/Angelman syndrome 2 (human)
chr12_-_35582521 0.84 ENSDART00000162175
ENSDART00000168958
SEC24 homolog C, COPII coat complex component
chr14_-_30960470 0.84 ENSDART00000129989
si:ch211-191o15.6
chr5_-_22573624 0.84 ENSDART00000131889
ENSDART00000080886
ENSDART00000147513
ENSDART00000080882
apoptosis-inducing factor, mitochondrion-associated 1
chr25_+_16646113 0.82 ENSDART00000110426
cat eye syndrome chromosome region, candidate 2
chr22_-_10752471 0.81 ENSDART00000081191
SAS-6 centriolar assembly protein
chr14_-_16082806 0.81 ENSDART00000165656
MAX dimerization protein 3
chr7_-_50367642 0.81 ENSDART00000134941
protein regulator of cytokinesis 1b
chr21_-_26490186 0.80 ENSDART00000009889
zgc:110540
chr8_-_30424182 0.80 ENSDART00000099021
dedicator of cytokinesis 8
chr13_-_32626247 0.78 ENSDART00000100663
WD repeat domain 35
chr17_-_5352924 0.78 ENSDART00000167275
SPT3 homolog, SAGA and STAGA complex component
chr12_-_35582683 0.78 ENSDART00000167933
SEC24 homolog C, COPII coat complex component
chr25_-_25142387 0.78 ENSDART00000031814
tumor susceptibility 101a
chr12_+_26467847 0.78 ENSDART00000022495
nudE neurodevelopment protein 1-like 1a
chr17_+_10748366 0.78 ENSDART00000018683
ENSDART00000097274
zgc:113944
chr18_-_40913294 0.77 ENSDART00000059196
ENSDART00000098878
polymerase (RNA) II (DNA directed) polypeptide I
chr9_+_42607138 0.77 ENSDART00000138133
ENSDART00000002027
GULP, engulfment adaptor PTB domain containing 1a
chr10_+_41939963 0.77 ENSDART00000126248
transmembrane protein 120B
chr25_-_14087377 0.76 ENSDART00000124140
zgc:101566
chr24_+_5893134 0.76 ENSDART00000077941
microtubule associated serine/threonine kinase-like
chr10_+_43117661 0.76 ENSDART00000024644
ENSDART00000186932
X-ray repair complementing defective repair in Chinese hamster cells 4
chr11_+_24348425 0.75 ENSDART00000089747
NFS1 cysteine desulfurase
chr13_-_36761379 0.75 ENSDART00000131534
ENSDART00000029824
mitogen-activated protein kinase kinase kinase kinase 5
chr9_+_23003208 0.74 ENSDART00000021060
ELL associated factor 2
chr11_+_1584747 0.74 ENSDART00000154583
si:dkey-40c23.2
chr19_+_32807236 0.74 ENSDART00000008698
serine/threonine kinase 3 (STE20 homolog, yeast)
chr19_-_24135824 0.73 ENSDART00000189505
ENSDART00000104087
THAP domain containing 7
chr8_+_23147609 0.72 ENSDART00000180284
GID complex subunit 8 homolog a (S. cerevisiae)
chr3_-_37681824 0.72 ENSDART00000185858
G patch domain containing 8
chr3_-_25492361 0.72 ENSDART00000147322
ENSDART00000055473
growth factor receptor-bound protein 2b
chr7_-_50367326 0.72 ENSDART00000141926
protein regulator of cytokinesis 1b
chr19_+_4968947 0.72 ENSDART00000003634
ENSDART00000134808
StAR-related lipid transfer (START) domain containing 3
chr18_-_14337450 0.72 ENSDART00000061435
heat shock factor binding protein 1b
chr22_+_29648854 0.72 ENSDART00000146280
BBSome interacting protein 1
chr15_+_1534644 0.72 ENSDART00000130413
structural maintenance of chromosomes 4
chr17_-_32743044 0.71 ENSDART00000135517
centromere protein F
chr5_+_44944778 0.71 ENSDART00000130428
ENSDART00000044361
ENSDART00000128825
ENSDART00000124637
ENSDART00000126066
ENSDART00000177635
doublesex and mab-3 related transcription factor 1
chr17_+_32500387 0.71 ENSDART00000018423
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide b
chr3_+_53116172 0.71 ENSDART00000115117
bromodomain containing 4
chr13_-_36844945 0.70 ENSDART00000129562
ENSDART00000150899
ninein (GSK3B interacting protein)
chr14_+_8638353 0.70 ENSDART00000163240
si:dkeyp-115e12.6
chr11_+_42422371 0.70 ENSDART00000163780
DENN/MADD domain containing 6Aa
chr4_-_20135919 0.70 ENSDART00000172230
centrosomal protein 83
chr4_+_6833583 0.69 ENSDART00000165179
ENSDART00000186134
ENSDART00000174507
dedicator of cytokinesis 4b
chr9_+_55455801 0.69 ENSDART00000144757
ENSDART00000186543
matrix-remodelling associated 5b
chr5_+_8196264 0.68 ENSDART00000174564
ENSDART00000161261
LMBR1 domain containing 2a
chr2_-_32384683 0.68 ENSDART00000182942
ENSDART00000141757
upstream binding transcription factor, like
chr23_-_912817 0.68 ENSDART00000192851
ras homolog gene family, member Ac
chr13_+_37653851 0.68 ENSDART00000141988
ENSDART00000126902
ENSDART00000100352
PHD finger protein 3
chr17_-_11417551 0.68 ENSDART00000128291
AT rich interactive domain 4A (RBP1-like)
chr21_-_13856689 0.67 ENSDART00000102197
family with sequence similarity 129, member Ba
chr17_-_23709347 0.67 ENSDART00000124661
3'-phosphoadenosine 5'-phosphosulfate synthase 2a
chr2_-_44777592 0.67 ENSDART00000113351
ENSDART00000169310
non-SMC condensin I complex, subunit D2
chr3_-_5228841 0.67 ENSDART00000092373
ENSDART00000182438
myosin, heavy chain 9b, non-muscle
chr22_+_30112390 0.67 ENSDART00000191715
adducin 3 (gamma) a
chr1_+_51066671 0.67 ENSDART00000064007
steroid-5-alpha-reductase, alpha polypeptide 2a
chr25_-_3647277 0.66 ENSDART00000166363
si:ch211-272n13.3
chr22_+_24603930 0.66 ENSDART00000180240
ENSDART00000164256

chr17_-_11417904 0.66 ENSDART00000103228
AT rich interactive domain 4A (RBP1-like)
chr3_+_35510040 0.65 ENSDART00000162757
ENSDART00000182383
trinucleotide repeat containing 6a
chr13_-_18011168 0.65 ENSDART00000144813
membrane-associated ring finger (C3HC4) 8
chr22_-_35063526 0.65 ENSDART00000162211
zgc:63733
chr2_+_2168547 0.65 ENSDART00000029347
HIG1 hypoxia inducible domain family, member 1A
chr23_-_25686894 0.65 ENSDART00000181420
ENSDART00000088208
low density lipoprotein receptor-related protein 1Ab
chr8_+_16738282 0.65 ENSDART00000134265
ENSDART00000100698
excision repair cross-complementation group 8
chr7_+_26844261 0.64 ENSDART00000079165
exostosin glycosyltransferase 2
chr23_-_21534738 0.63 ENSDART00000134587
regulator of chromosome condensation 2
chr4_+_16725960 0.63 ENSDART00000034441
t-complex 11, testis-specific-like 2
chr8_+_17167876 0.63 ENSDART00000134665
centromere protein H
chr2_+_44518636 0.63 ENSDART00000153733
PAS domain containing serine/threonine kinase
chr10_+_17235370 0.63 ENSDART00000038780
signal peptide peptidase 3
chr22_-_3152357 0.63 ENSDART00000170983
lamin B2
chr12_+_3912544 0.62 ENSDART00000013465
T-box 6
chr24_-_27256673 0.62 ENSDART00000181182
zinc finger, MYND-type containing 11
chr18_+_20566817 0.62 ENSDART00000100716
BH3 interacting domain death agonist
chr19_+_42047427 0.62 ENSDART00000180225
ENSDART00000145356
si:ch211-13c6.2
chr18_+_13077800 0.61 ENSDART00000161153
gigaxonin
chr4_-_20135406 0.61 ENSDART00000161343
centrosomal protein 83
chr20_-_45709990 0.61 ENSDART00000027482
glycerophosphocholine phosphodiesterase 1
chr1_+_53321878 0.61 ENSDART00000143909
TBC1 domain family, member 9 (with GRAM domain)
chr19_-_47997424 0.61 ENSDART00000081675
catenin, beta 2
chr14_+_51056605 0.61 ENSDART00000159639

chr7_+_7511914 0.61 ENSDART00000172848
chloride channel 3
chr10_+_17371356 0.61 ENSDART00000122663
signal peptide peptidase 3
chr5_-_42661012 0.61 ENSDART00000158339
Pim proto-oncogene, serine/threonine kinase, related 58
chr24_-_23716097 0.60 ENSDART00000084954
ENSDART00000129028
phosphatidylinositol glycan anchor biosynthesis, class N
chr8_+_10862353 0.60 ENSDART00000140717
bromodomain and PHD finger containing, 3b
chr7_-_56766973 0.60 ENSDART00000020967
casein kinase 2, alpha prime polypeptide a
chr23_-_21534455 0.59 ENSDART00000139092
regulator of chromosome condensation 2
chr5_-_71722257 0.59 ENSDART00000013404
adenylate kinase 1
chr24_-_35707552 0.59 ENSDART00000165199
microtubule-associated protein, RP/EB family, member 2
chr20_+_38671894 0.59 ENSDART00000146544
MpV17 mitochondrial inner membrane protein
chr1_+_11107688 0.59 ENSDART00000109858
kinetochore-localized astrin/SPAG5 binding protein
chr20_-_42378865 0.58 ENSDART00000139912
ENSDART00000015801
discoidin, CUB and LCCL domain containing 1
chr4_+_6833735 0.58 ENSDART00000136355
dedicator of cytokinesis 4b
chr5_-_19963537 0.57 ENSDART00000148146
si:dkey-234h16.7
chr20_-_33487729 0.57 ENSDART00000061843
SMEK homolog 1, suppressor of mek1 (Dictyostelium)
chr19_-_9503473 0.57 ENSDART00000091615
intermediate filament family orphan 1a
chr18_-_15532016 0.56 ENSDART00000165279
PTPRF interacting protein, binding protein 1b (liprin beta 1)
chr17_+_45737992 0.56 ENSDART00000135073
ENSDART00000143525
ENSDART00000158165
ENSDART00000184167
ENSDART00000109525
asparaginase homolog (S. cerevisiae)
chr13_-_22961605 0.56 ENSDART00000143112
ENSDART00000057641
tetraspanin 15
chr6_+_29791164 0.56 ENSDART00000017424
prothymosin, alpha a
chr12_+_17436904 0.56 ENSDART00000079130
ATPase family, AAA domain containing 1b
chr11_+_13024002 0.56 ENSDART00000104113
basic transcription factor 3-like 4
chr7_+_25858380 0.56 ENSDART00000148780
ENSDART00000079218
myotubularin related protein 1a
chr7_+_21787507 0.55 ENSDART00000100936
transmembrane protein 88 b
chr19_-_10324182 0.55 ENSDART00000151352
ENSDART00000151162
ENSDART00000023571
U2 small nuclear RNA auxiliary factor 2b
chr23_+_22873415 0.55 ENSDART00000135130
arginine-glutamic acid dipeptide (RE) repeats a
chr6_-_34860574 0.55 ENSDART00000073957
solute carrier family 35 (UDP-GlcA/UDP-GalNAc transporter), member D1a
chr17_-_26719821 0.55 ENSDART00000186813
calmodulin 1a
chr7_-_24995631 0.55 ENSDART00000173955
ENSDART00000173791
REST corepressor 2
chr15_+_26941063 0.55 ENSDART00000149957
breast carcinoma amplified sequence 3
chr7_+_1550966 0.55 ENSDART00000177863
ENSDART00000126840
SPT16 homolog, facilitates chromatin remodeling subunit
chr8_+_12930216 0.55 ENSDART00000115405
zgc:103670
chr5_+_19314574 0.54 ENSDART00000133247
RUN and SH3 domain containing 2
chr9_+_24088062 0.54 ENSDART00000126198
leucine rich repeat (in FLII) interacting protein 1a
chr19_-_6134802 0.54 ENSDART00000140051
capicua transcriptional repressor a
chr7_+_52712807 0.54 ENSDART00000174095
ENSDART00000174377
ENSDART00000174061
ENSDART00000174094
ENSDART00000110906
ENSDART00000174071
ENSDART00000174238
zinc finger protein 280D
chr3_-_13546610 0.54 ENSDART00000159647
amidohydrolase domain containing 2
chr9_-_28939796 0.54 ENSDART00000101269
erythrocyte membrane protein band 4.1 like 5
chr10_+_16036573 0.54 ENSDART00000188757
lamin B1
chr17_-_32743249 0.54 ENSDART00000176858
ENSDART00000189622
centromere protein F
chr15_-_18432673 0.54 ENSDART00000146853
neural cell adhesion molecule 1b
chr21_+_13327527 0.53 ENSDART00000114294
small nuclear ribonucleoprotein D3 polypeptide, like
chr3_+_7771420 0.53 ENSDART00000156809
ENSDART00000156309
hook microtubule-tethering protein 2
chr22_+_10232527 0.53 ENSDART00000139297
si:dkeyp-87e7.4
chr10_+_16036246 0.52 ENSDART00000141586
ENSDART00000135868
ENSDART00000065037
ENSDART00000124502
lamin B1
chr21_-_36453594 0.52 ENSDART00000193176
CCR4-NOT transcription complex, subunit 8
chr20_-_53949798 0.52 ENSDART00000153435
protein phosphatase 2, regulatory subunit B', gamma b

Network of associatons between targets according to the STRING database.

First level regulatory network of foxf1+foxf2a+foxf2b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.2 GO:0071896 protein localization to adherens junction(GO:0071896)
0.3 1.0 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.3 0.9 GO:0002940 tRNA N2-guanine methylation(GO:0002940)
0.3 1.4 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.3 1.9 GO:0021534 cell proliferation in hindbrain(GO:0021534)
0.3 1.4 GO:0051792 medium-chain fatty acid biosynthetic process(GO:0051792)
0.3 2.1 GO:0045719 negative regulation of glycogen biosynthetic process(GO:0045719) negative regulation of glycogen metabolic process(GO:0070874)
0.3 1.5 GO:0090245 axis elongation involved in somitogenesis(GO:0090245)
0.2 1.0 GO:0003413 chondrocyte differentiation involved in endochondral bone morphogenesis(GO:0003413) growth plate cartilage chondrocyte differentiation(GO:0003418)
0.2 0.7 GO:0097500 receptor localization to nonmotile primary cilium(GO:0097500) protein localization to ciliary membrane(GO:1903441)
0.2 0.7 GO:0030238 male sex determination(GO:0030238)
0.2 0.7 GO:1901407 regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901407)
0.2 0.9 GO:0002495 antigen processing and presentation of peptide antigen via MHC class II(GO:0002495)
0.2 0.9 GO:2000275 regulation of oxidative phosphorylation uncoupler activity(GO:2000275)
0.2 1.4 GO:0006283 transcription-coupled nucleotide-excision repair(GO:0006283)
0.2 0.8 GO:0040016 embryonic cleavage(GO:0040016)
0.2 0.6 GO:0000103 sulfate assimilation(GO:0000103) purine ribonucleoside bisphosphate metabolic process(GO:0034035) purine ribonucleoside bisphosphate biosynthetic process(GO:0034036) 3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427) 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process(GO:0050428)
0.2 0.6 GO:0046048 pyrimidine ribonucleoside diphosphate metabolic process(GO:0009193) UDP metabolic process(GO:0046048)
0.2 1.1 GO:2000576 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.2 0.7 GO:0010032 meiotic chromosome condensation(GO:0010032)
0.2 0.5 GO:0061188 regulation of chromatin silencing at rDNA(GO:0061187) negative regulation of chromatin silencing at rDNA(GO:0061188)
0.2 0.6 GO:2001244 positive regulation of intrinsic apoptotic signaling pathway(GO:2001244)
0.2 0.8 GO:0006266 DNA ligation(GO:0006266) immunoglobulin V(D)J recombination(GO:0033152) DNA ligation involved in DNA repair(GO:0051103)
0.2 0.9 GO:0090133 mesendoderm migration(GO:0090133) cell migration involved in mesendoderm migration(GO:0090134)
0.1 0.3 GO:0036037 CD8-positive, alpha-beta T cell activation(GO:0036037)
0.1 0.9 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.1 0.7 GO:0034454 microtubule anchoring at centrosome(GO:0034454)
0.1 1.5 GO:0051231 mitotic spindle elongation(GO:0000022) spindle elongation(GO:0051231) mitotic spindle midzone assembly(GO:0051256)
0.1 0.4 GO:0031591 wybutosine metabolic process(GO:0031590) wybutosine biosynthetic process(GO:0031591)
0.1 1.0 GO:0006542 glutamine biosynthetic process(GO:0006542)
0.1 1.2 GO:0006465 signal peptide processing(GO:0006465)
0.1 0.5 GO:0006046 N-acetylglucosamine catabolic process(GO:0006046)
0.1 0.8 GO:0060052 neurofilament cytoskeleton organization(GO:0060052)
0.1 2.0 GO:0051310 metaphase plate congression(GO:0051310)
0.1 0.4 GO:0048917 posterior lateral line ganglion development(GO:0048917)
0.1 1.3 GO:0021694 cerebellar Purkinje cell layer formation(GO:0021694) cerebellar Purkinje cell differentiation(GO:0021702)
0.1 1.9 GO:0090279 regulation of calcium ion import(GO:0090279)
0.1 0.7 GO:0070650 actin filament bundle distribution(GO:0070650)
0.1 0.3 GO:0030423 targeting of mRNA for destruction involved in RNA interference(GO:0030423)
0.1 0.6 GO:0097250 mitochondrial respiratory chain supercomplex assembly(GO:0097250)
0.1 1.6 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.1 0.3 GO:0034398 telomere localization(GO:0034397) telomere tethering at nuclear periphery(GO:0034398) meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic telomere clustering(GO:0045141) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome localization to nuclear envelope involved in homologous chromosome segregation(GO:0090220) chromosome attachment to the nuclear envelope(GO:0097240)
0.1 0.4 GO:0033313 meiotic cell cycle checkpoint(GO:0033313)
0.1 0.7 GO:1902766 skeletal muscle satellite cell migration(GO:1902766)
0.1 0.8 GO:0032515 negative regulation of phosphoprotein phosphatase activity(GO:0032515)
0.1 0.8 GO:0003422 growth plate cartilage morphogenesis(GO:0003422) chondrocyte intercalation involved in growth plate cartilage morphogenesis(GO:0003428)
0.1 1.0 GO:0043928 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.1 0.6 GO:0021523 somatic motor neuron differentiation(GO:0021523)
0.1 0.3 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
0.1 0.6 GO:0009188 ADP biosynthetic process(GO:0006172) purine nucleoside diphosphate biosynthetic process(GO:0009136) purine ribonucleoside diphosphate biosynthetic process(GO:0009180) ribonucleoside diphosphate biosynthetic process(GO:0009188)
0.1 1.4 GO:0043001 Golgi to plasma membrane protein transport(GO:0043001)
0.1 1.2 GO:0034724 DNA replication-independent nucleosome organization(GO:0034724)
0.1 0.2 GO:0097237 cellular response to antibiotic(GO:0071236) cellular response to toxic substance(GO:0097237)
0.1 0.2 GO:0019262 N-acetylneuraminate catabolic process(GO:0019262)
0.1 0.8 GO:0045444 fat cell differentiation(GO:0045444)
0.1 0.5 GO:0021634 optic nerve formation(GO:0021634)
0.1 2.3 GO:0048263 determination of dorsal identity(GO:0048263)
0.1 0.3 GO:0044210 'de novo' CTP biosynthetic process(GO:0044210)
0.1 0.6 GO:0097374 sensory neuron axon guidance(GO:0097374)
0.1 0.8 GO:0035721 intraciliary retrograde transport(GO:0035721)
0.1 0.9 GO:0090308 methylation-dependent chromatin silencing(GO:0006346) positive regulation of chromatin silencing(GO:0031937) regulation of methylation-dependent chromatin silencing(GO:0090308) positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.1 0.2 GO:0061178 insulin secretion involved in cellular response to glucose stimulus(GO:0035773) regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061178)
0.1 0.5 GO:0021550 medulla oblongata development(GO:0021550) dorsal motor nucleus of vagus nerve development(GO:0021744)
0.1 0.4 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.1 0.6 GO:0035372 protein localization to microtubule(GO:0035372) protein localization to microtubule plus-end(GO:1904825)
0.1 0.7 GO:0007076 mitotic chromosome condensation(GO:0007076)
0.1 0.3 GO:0007412 axon target recognition(GO:0007412)
0.1 0.4 GO:2001106 regulation of guanyl-nucleotide exchange factor activity(GO:1905097) regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.1 0.7 GO:0000729 DNA double-strand break processing(GO:0000729)
0.1 0.3 GO:0036498 IRE1-mediated unfolded protein response(GO:0036498)
0.1 0.2 GO:0048169 regulation of long-term neuronal synaptic plasticity(GO:0048169)
0.1 0.2 GO:0001514 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.1 0.4 GO:0097107 postsynaptic density assembly(GO:0097107) modulation of excitatory postsynaptic potential(GO:0098815) positive regulation of excitatory postsynaptic potential(GO:2000463)
0.1 0.2 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.1 1.1 GO:0042953 lipoprotein transport(GO:0042953) lipoprotein localization(GO:0044872)
0.1 0.3 GO:0016559 peroxisome fission(GO:0016559)
0.1 1.0 GO:0018095 protein polyglutamylation(GO:0018095)
0.1 0.5 GO:0061098 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741) positive regulation of protein tyrosine kinase activity(GO:0061098) positive regulation of receptor activity(GO:2000273)
0.1 0.4 GO:0044211 CTP salvage(GO:0044211)
0.1 0.2 GO:2000637 negative regulation of hippo signaling(GO:0035331) positive regulation of posttranscriptional gene silencing(GO:0060148) positive regulation of gene silencing by miRNA(GO:2000637)
0.1 1.9 GO:0048634 regulation of muscle organ development(GO:0048634)
0.1 0.4 GO:1901224 positive regulation of NIK/NF-kappaB signaling(GO:1901224)
0.0 0.8 GO:0015693 magnesium ion transport(GO:0015693)
0.0 0.1 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 1.0 GO:0031163 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.0 0.3 GO:0048478 replication fork protection(GO:0048478)
0.0 0.8 GO:0000727 double-strand break repair via break-induced replication(GO:0000727)
0.0 0.4 GO:0070498 interleukin-1-mediated signaling pathway(GO:0070498)
0.0 0.5 GO:0048845 venous blood vessel morphogenesis(GO:0048845)
0.0 1.2 GO:0007064 mitotic sister chromatid cohesion(GO:0007064)
0.0 3.0 GO:0030917 midbrain-hindbrain boundary development(GO:0030917)
0.0 0.9 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.0 0.7 GO:0060211 regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060211) positive regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060213) regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900151) positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900153)
0.0 0.1 GO:0032570 response to progesterone(GO:0032570)
0.0 0.6 GO:0044154 histone H3-K14 acetylation(GO:0044154)
0.0 0.2 GO:0070254 mucus secretion(GO:0070254)
0.0 0.5 GO:0006611 protein export from nucleus(GO:0006611)
0.0 0.6 GO:0030317 sperm motility(GO:0030317)
0.0 0.5 GO:0071357 response to type I interferon(GO:0034340) type I interferon signaling pathway(GO:0060337) cellular response to type I interferon(GO:0071357)
0.0 0.9 GO:0030261 chromosome condensation(GO:0030261)
0.0 0.2 GO:0031340 positive regulation of vesicle fusion(GO:0031340)
0.0 2.0 GO:0099515 vesicle transport along actin filament(GO:0030050) actin filament-based transport(GO:0099515)
0.0 0.6 GO:0000712 resolution of meiotic recombination intermediates(GO:0000712)
0.0 0.2 GO:0032964 collagen biosynthetic process(GO:0032964)
0.0 0.7 GO:0043966 histone H3 acetylation(GO:0043966)
0.0 1.1 GO:0006506 GPI anchor biosynthetic process(GO:0006506)
0.0 1.2 GO:0014029 neural crest formation(GO:0014029)
0.0 0.4 GO:0008585 female gonad development(GO:0008585)
0.0 0.4 GO:0046548 retinal rod cell development(GO:0046548)
0.0 0.3 GO:0060005 reflex(GO:0060004) vestibular reflex(GO:0060005)
0.0 1.5 GO:0051016 barbed-end actin filament capping(GO:0051016)
0.0 0.5 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
0.0 0.3 GO:0042554 superoxide anion generation(GO:0042554)
0.0 0.7 GO:0014812 muscle cell migration(GO:0014812)
0.0 1.0 GO:0030048 actin filament-based movement(GO:0030048)
0.0 0.4 GO:0044380 protein localization to cytoskeleton(GO:0044380)
0.0 0.1 GO:0070301 cellular response to hydrogen peroxide(GO:0070301)
0.0 0.7 GO:0051788 response to misfolded protein(GO:0051788) cellular response to misfolded protein(GO:0071218)
0.0 0.3 GO:2000290 smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021910) regulation of myotome development(GO:2000290)
0.0 0.6 GO:0007520 myoblast fusion(GO:0007520)
0.0 0.7 GO:0007548 sex differentiation(GO:0007548)
0.0 0.3 GO:0055129 proline biosynthetic process(GO:0006561) L-proline biosynthetic process(GO:0055129)
0.0 1.0 GO:0046883 regulation of hormone secretion(GO:0046883)
0.0 0.6 GO:0046475 glycerophospholipid catabolic process(GO:0046475)
0.0 0.1 GO:0035608 protein deglutamylation(GO:0035608)
0.0 0.4 GO:0045116 protein neddylation(GO:0045116)
0.0 0.5 GO:0031952 regulation of protein autophosphorylation(GO:0031952)
0.0 0.5 GO:0007257 activation of JUN kinase activity(GO:0007257) positive regulation of JUN kinase activity(GO:0043507)
0.0 0.7 GO:0035329 hippo signaling(GO:0035329)
0.0 0.1 GO:0042769 DNA damage response, detection of DNA damage(GO:0042769)
0.0 0.5 GO:0045879 negative regulation of smoothened signaling pathway(GO:0045879)
0.0 0.8 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.0 0.6 GO:0032526 response to retinoic acid(GO:0032526)
0.0 0.2 GO:0090660 regulation of microtubule polymerization(GO:0031113) cerebrospinal fluid circulation(GO:0090660)
0.0 0.2 GO:0032926 negative regulation of activin receptor signaling pathway(GO:0032926)
0.0 0.3 GO:0051382 kinetochore assembly(GO:0051382)
0.0 0.4 GO:0046330 positive regulation of JNK cascade(GO:0046330)
0.0 0.1 GO:0019441 tryptophan catabolic process to kynurenine(GO:0019441)
0.0 0.3 GO:0030878 thyroid gland development(GO:0030878)
0.0 0.1 GO:0097476 spinal cord motor neuron migration(GO:0097476) lateral motor column neuron migration(GO:0097477)
0.0 0.7 GO:0030301 cholesterol transport(GO:0030301)
0.0 0.1 GO:1900619 acetylcholine metabolic process(GO:0008291) acetate ester metabolic process(GO:1900619)
0.0 0.2 GO:0043462 regulation of ATPase activity(GO:0043462)
0.0 0.3 GO:0034643 establishment of mitochondrion localization, microtubule-mediated(GO:0034643) mitochondrion transport along microtubule(GO:0047497) establishment of mitochondrion localization(GO:0051654)
0.0 0.5 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.2 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0 0.3 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.0 0.8 GO:0043044 ATP-dependent chromatin remodeling(GO:0043044)
0.0 0.1 GO:0070375 ERK5 cascade(GO:0070375) regulation of ERK5 cascade(GO:0070376) positive regulation of ERK5 cascade(GO:0070378)
0.0 0.4 GO:0043574 protein targeting to peroxisome(GO:0006625) peroxisomal transport(GO:0043574) protein localization to peroxisome(GO:0072662) establishment of protein localization to peroxisome(GO:0072663)
0.0 0.4 GO:0051092 positive regulation of NF-kappaB transcription factor activity(GO:0051092)
0.0 0.7 GO:0071875 adrenergic receptor signaling pathway(GO:0071875)
0.0 0.5 GO:0030038 contractile actin filament bundle assembly(GO:0030038) stress fiber assembly(GO:0043149)
0.0 0.9 GO:0006334 nucleosome assembly(GO:0006334)
0.0 0.3 GO:0035675 neuromast hair cell development(GO:0035675)
0.0 0.9 GO:0000723 telomere maintenance(GO:0000723) telomere organization(GO:0032200)
0.0 0.2 GO:0086010 membrane depolarization during action potential(GO:0086010)
0.0 0.1 GO:0016578 histone deubiquitination(GO:0016578)
0.0 0.9 GO:0033339 pectoral fin development(GO:0033339)
0.0 0.2 GO:0021522 spinal cord motor neuron differentiation(GO:0021522)
0.0 0.6 GO:0030514 negative regulation of BMP signaling pathway(GO:0030514)
0.0 0.4 GO:0003231 cardiac ventricle development(GO:0003231)
0.0 0.7 GO:0018107 peptidyl-threonine phosphorylation(GO:0018107)
0.0 0.1 GO:0007031 peroxisome organization(GO:0007031)
0.0 0.5 GO:0032465 regulation of cytokinesis(GO:0032465)
0.0 0.7 GO:0007224 smoothened signaling pathway(GO:0007224)
0.0 0.4 GO:0019432 triglyceride biosynthetic process(GO:0019432)
0.0 0.2 GO:0051489 regulation of filopodium assembly(GO:0051489)
0.0 1.1 GO:0042594 response to starvation(GO:0042594)
0.0 0.1 GO:0032309 icosanoid secretion(GO:0032309) arachidonic acid secretion(GO:0050482) arachidonate transport(GO:1903963)
0.0 0.2 GO:0036230 granulocyte activation(GO:0036230) neutrophil activation(GO:0042119)
0.0 0.6 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.0 0.0 GO:0018171 peptidyl-cysteine oxidation(GO:0018171)
0.0 0.2 GO:0048936 peripheral nervous system neuron axonogenesis(GO:0048936)
0.0 0.5 GO:0032272 negative regulation of actin filament polymerization(GO:0030837) negative regulation of protein polymerization(GO:0032272)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.4 GO:0097524 sperm plasma membrane(GO:0097524)
0.3 1.2 GO:0098553 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553)
0.3 0.8 GO:0098536 deuterosome(GO:0098536)
0.3 0.8 GO:0005958 DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958)
0.1 0.4 GO:0031213 RSF complex(GO:0031213)
0.1 1.5 GO:1990023 mitotic spindle midzone(GO:1990023)
0.1 0.8 GO:0030914 STAGA complex(GO:0030914)
0.1 0.3 GO:0070578 RISC-loading complex(GO:0070578)
0.1 0.4 GO:0033186 CAF-1 complex(GO:0033186)
0.1 1.5 GO:0000243 commitment complex(GO:0000243)
0.1 0.3 GO:0009330 DNA topoisomerase complex (ATP-hydrolyzing)(GO:0009330)
0.1 1.1 GO:0035101 FACT complex(GO:0035101)
0.1 0.3 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
0.1 0.8 GO:0030991 intraciliary transport particle A(GO:0030991)
0.1 0.7 GO:0032783 ELL-EAF complex(GO:0032783)
0.1 1.0 GO:0034451 centriolar satellite(GO:0034451)
0.1 0.6 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.1 0.8 GO:0031010 ISWI-type complex(GO:0031010)
0.1 0.7 GO:0034464 BBSome(GO:0034464)
0.1 1.6 GO:0030127 COPII vesicle coat(GO:0030127)
0.1 1.0 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.1 0.3 GO:0097268 cytoophidium(GO:0097268)
0.1 0.3 GO:0097134 cyclin E1-CDK2 complex(GO:0097134)
0.1 0.9 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.1 0.3 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.1 0.7 GO:0097431 mitotic spindle pole(GO:0097431)
0.1 0.9 GO:0071014 post-mRNA release spliceosomal complex(GO:0071014)
0.1 0.4 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.1 0.2 GO:1990879 CST complex(GO:1990879)
0.1 0.3 GO:0035032 phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.1 0.4 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.1 0.4 GO:0044232 organelle membrane contact site(GO:0044232)
0.1 0.3 GO:0000835 ER ubiquitin ligase complex(GO:0000835) Hrd1p ubiquitin ligase complex(GO:0000836)
0.1 2.3 GO:0005637 nuclear inner membrane(GO:0005637)
0.1 1.0 GO:0030057 desmosome(GO:0030057)
0.0 0.7 GO:0042555 MCM complex(GO:0042555)
0.0 0.3 GO:0031231 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.0 0.6 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.0 0.6 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 2.1 GO:0031941 filamentous actin(GO:0031941)
0.0 0.8 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 0.2 GO:0098842 postsynaptic early endosome(GO:0098842)
0.0 4.5 GO:0005882 intermediate filament(GO:0005882)
0.0 5.5 GO:0000775 chromosome, centromeric region(GO:0000775)
0.0 0.3 GO:0001401 mitochondrial sorting and assembly machinery complex(GO:0001401)
0.0 1.8 GO:0005814 centriole(GO:0005814)
0.0 0.5 GO:0048179 activin receptor complex(GO:0048179)
0.0 2.4 GO:0031901 early endosome membrane(GO:0031901)
0.0 0.4 GO:0030904 retromer complex(GO:0030904)
0.0 0.4 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 0.6 GO:0070775 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 1.0 GO:0035861 site of double-strand break(GO:0035861)
0.0 0.3 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 0.2 GO:0070390 transcription export complex 2(GO:0070390)
0.0 0.2 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.0 0.1 GO:0032983 kainate selective glutamate receptor complex(GO:0032983)
0.0 0.3 GO:0030014 CCR4-NOT complex(GO:0030014)
0.0 0.2 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.0 0.6 GO:0035371 microtubule plus-end(GO:0035371) spindle midzone(GO:0051233)
0.0 2.4 GO:0036064 ciliary basal body(GO:0036064)
0.0 2.3 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 0.4 GO:1990589 ATF4-CREB1 transcription factor complex(GO:1990589)
0.0 1.6 GO:0031514 motile cilium(GO:0031514)
0.0 1.2 GO:0008305 integrin complex(GO:0008305)
0.0 0.9 GO:0000922 spindle pole(GO:0000922)
0.0 0.8 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 1.1 GO:0030286 dynein complex(GO:0030286)
0.0 0.5 GO:0005903 brush border(GO:0005903)
0.0 0.7 GO:0000781 chromosome, telomeric region(GO:0000781)
0.0 0.3 GO:0005682 U5 snRNP(GO:0005682)
0.0 0.3 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 0.3 GO:0098563 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 0.4 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.2 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.0 0.1 GO:0060171 stereocilium membrane(GO:0060171)
0.0 0.1 GO:0000798 nuclear cohesin complex(GO:0000798) mitotic cohesin complex(GO:0030892) nuclear mitotic cohesin complex(GO:0034990) nuclear meiotic cohesin complex(GO:0034991)
0.0 0.3 GO:0071564 npBAF complex(GO:0071564)
0.0 0.4 GO:0035869 ciliary transition zone(GO:0035869)
0.0 1.3 GO:0005871 kinesin complex(GO:0005871)
0.0 0.2 GO:0044295 axonal growth cone(GO:0044295)
0.0 0.5 GO:0030131 clathrin adaptor complex(GO:0030131)
0.0 2.1 GO:0016459 myosin complex(GO:0016459)
0.0 0.4 GO:0016514 SWI/SNF complex(GO:0016514)
0.0 0.1 GO:1990130 Iml1 complex(GO:1990130)
0.0 0.4 GO:0043186 P granule(GO:0043186)
0.0 0.8 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 1.0 GO:0005884 actin filament(GO:0005884)
0.0 1.2 GO:0055037 recycling endosome(GO:0055037)
0.0 0.5 GO:0042641 actomyosin(GO:0042641)
0.0 0.6 GO:0016342 catenin complex(GO:0016342)
0.0 1.9 GO:0014069 postsynaptic density(GO:0014069)
0.0 0.2 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.0 0.9 GO:0031228 integral component of Golgi membrane(GO:0030173) intrinsic component of Golgi membrane(GO:0031228)
0.0 0.1 GO:0061617 MICOS complex(GO:0061617)
0.0 0.3 GO:0072686 mitotic spindle(GO:0072686)
0.0 0.7 GO:0000793 condensed chromosome(GO:0000793)
0.0 0.4 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.0 0.4 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 0.4 GO:0016605 PML body(GO:0016605)
0.0 0.2 GO:0045263 proton-transporting ATP synthase complex, coupling factor F(o)(GO:0045263)
0.0 0.2 GO:0098862 stereocilium bundle(GO:0032421) cluster of actin-based cell projections(GO:0098862)
0.0 0.1 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.0 4.4 GO:0005694 chromosome(GO:0005694)
0.0 0.3 GO:0000159 protein phosphatase type 2A complex(GO:0000159)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.8 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.4 2.3 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.2 0.9 GO:0004809 tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
0.2 1.4 GO:0008126 acetylesterase activity(GO:0008126)
0.2 0.6 GO:0004020 adenylylsulfate kinase activity(GO:0004020) sulfate adenylyltransferase activity(GO:0004779) sulfate adenylyltransferase (ATP) activity(GO:0004781)
0.2 1.9 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.2 0.7 GO:0033765 3-oxo-5-alpha-steroid 4-dehydrogenase activity(GO:0003865) steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765) enone reductase activity(GO:0035671) cholestenone 5-alpha-reductase activity(GO:0047751)
0.2 1.2 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.2 0.6 GO:2001070 starch binding(GO:2001070)
0.1 0.6 GO:0051377 mannose-ethanolamine phosphotransferase activity(GO:0051377)
0.1 0.6 GO:0008310 single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
0.1 2.0 GO:0070840 dynein complex binding(GO:0070840)
0.1 0.4 GO:0071532 ankyrin repeat binding(GO:0071532)
0.1 1.0 GO:0016880 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
0.1 0.6 GO:0005463 UDP-glucuronic acid transmembrane transporter activity(GO:0005461) UDP-N-acetylgalactosamine transmembrane transporter activity(GO:0005463)
0.1 0.6 GO:0050509 N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity(GO:0050509)
0.1 0.7 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.1 0.5 GO:0035575 histone demethylase activity (H4-K20 specific)(GO:0035575)
0.1 0.8 GO:0019136 deoxynucleoside kinase activity(GO:0019136)
0.1 0.4 GO:0070513 death domain binding(GO:0070513)
0.1 0.3 GO:0003918 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.1 1.2 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.1 0.9 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.1 0.5 GO:0008545 JUN kinase kinase activity(GO:0008545)
0.1 0.3 GO:0004174 electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649)
0.1 1.0 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.1 0.5 GO:0016361 activin receptor activity, type I(GO:0016361)
0.1 1.3 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.1 0.3 GO:0032296 ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296) pre-miRNA binding(GO:0070883)
0.1 0.8 GO:0034647 histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647)
0.1 0.6 GO:0016316 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316)
0.1 0.9 GO:0004046 aminoacylase activity(GO:0004046)
0.1 1.0 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.1 1.4 GO:0002039 p53 binding(GO:0002039)
0.1 1.0 GO:0070739 protein-glutamic acid ligase activity(GO:0070739) tubulin-glutamic acid ligase activity(GO:0070740)
0.1 1.5 GO:0001968 fibronectin binding(GO:0001968)
0.1 0.3 GO:0003883 CTP synthase activity(GO:0003883)
0.1 0.4 GO:0008158 hedgehog receptor activity(GO:0008158)
0.1 0.4 GO:0043140 ATP-dependent 3'-5' DNA helicase activity(GO:0043140) single-stranded DNA-dependent ATP-dependent 3'-5' DNA helicase activity(GO:1990518)
0.1 0.6 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.1 0.6 GO:0004067 asparaginase activity(GO:0004067)
0.1 0.6 GO:0045294 alpha-catenin binding(GO:0045294)
0.1 0.3 GO:0003796 lysozyme activity(GO:0003796)
0.1 0.8 GO:0051721 protein phosphatase 2A binding(GO:0051721)
0.1 0.2 GO:0052717 tRNA-specific adenosine-34 deaminase activity(GO:0052717)
0.1 0.7 GO:0016783 sulfurtransferase activity(GO:0016783)
0.1 0.5 GO:0043515 kinetochore binding(GO:0043515)
0.1 0.4 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.1 0.6 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.1 0.4 GO:0004849 uridine kinase activity(GO:0004849)
0.1 1.9 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435) phospholipase C activity(GO:0004629)
0.0 0.1 GO:0004061 arylformamidase activity(GO:0004061)
0.0 0.6 GO:0004017 adenylate kinase activity(GO:0004017)
0.0 0.2 GO:0008281 sulfonylurea receptor activity(GO:0008281)
0.0 0.2 GO:0001223 transcription coactivator binding(GO:0001223)
0.0 0.9 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.6 GO:0043994 H3 histone acetyltransferase activity(GO:0010484) histone acetyltransferase activity (H3-K23 specific)(GO:0043994)
0.0 0.8 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 1.6 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.0 2.0 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 0.8 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 0.1 GO:0004345 glucose-6-phosphate dehydrogenase activity(GO:0004345)
0.0 0.2 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.0 0.1 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.0 0.4 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.0 0.9 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 1.2 GO:0019213 deacetylase activity(GO:0019213)
0.0 0.2 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.0 0.2 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.0 0.9 GO:0042287 MHC protein binding(GO:0042287)
0.0 0.2 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.0 1.5 GO:0031491 nucleosome binding(GO:0031491)
0.0 0.4 GO:0030544 Hsp70 protein binding(GO:0030544)
0.0 0.2 GO:0016312 inositol bisphosphate phosphatase activity(GO:0016312)
0.0 0.8 GO:0034062 DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)
0.0 0.5 GO:0072542 phosphatase activator activity(GO:0019211) protein phosphatase activator activity(GO:0072542)
0.0 0.4 GO:0005537 mannose binding(GO:0005537)
0.0 0.3 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 1.5 GO:0008094 DNA-dependent ATPase activity(GO:0008094)
0.0 0.1 GO:0004534 5'-3' exoribonuclease activity(GO:0004534)
0.0 1.0 GO:0031490 chromatin DNA binding(GO:0031490)
0.0 0.1 GO:0034416 bisphosphoglycerate phosphatase activity(GO:0034416)
0.0 0.4 GO:0097602 cullin family protein binding(GO:0097602)
0.0 0.3 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.0 0.6 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.3 GO:0005080 protein kinase C binding(GO:0005080)
0.0 0.2 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 0.4 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.5 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.2 GO:0043047 single-stranded telomeric DNA binding(GO:0043047) sequence-specific single stranded DNA binding(GO:0098847)
0.0 0.5 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.4 GO:0000339 RNA cap binding(GO:0000339)
0.0 0.3 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 2.1 GO:0042803 protein homodimerization activity(GO:0042803)
0.0 0.1 GO:0030298 receptor signaling protein tyrosine kinase activator activity(GO:0030298)
0.0 1.5 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0 0.2 GO:0048185 activin binding(GO:0048185)
0.0 0.3 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.0 0.1 GO:0004142 diacylglycerol cholinephosphotransferase activity(GO:0004142)
0.0 0.6 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.0 0.3 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0 0.5 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.6 GO:0031593 polyubiquitin binding(GO:0031593)
0.0 0.4 GO:0008175 tRNA methyltransferase activity(GO:0008175)
0.0 0.2 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.0 0.1 GO:0004104 cholinesterase activity(GO:0004104)
0.0 0.3 GO:0030165 PDZ domain binding(GO:0030165)
0.0 0.4 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.0 1.9 GO:0019901 protein kinase binding(GO:0019901)
0.0 3.4 GO:0008017 microtubule binding(GO:0008017)
0.0 0.2 GO:0048495 Roundabout binding(GO:0048495)
0.0 0.2 GO:0097153 cysteine-type endopeptidase activity involved in apoptotic process(GO:0097153)
0.0 2.0 GO:0000149 SNARE binding(GO:0000149)
0.0 0.1 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.0 0.3 GO:0008483 transaminase activity(GO:0008483)
0.0 0.1 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.5 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.0 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.1 1.9 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.1 0.5 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.1 0.5 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.1 2.3 PID AURORA B PATHWAY Aurora B signaling
0.1 1.5 PID NECTIN PATHWAY Nectin adhesion pathway
0.1 0.5 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.1 0.9 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.1 0.2 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.0 2.0 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.0 1.9 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 0.8 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.0 0.8 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 0.8 PID MYC PATHWAY C-MYC pathway
0.0 0.3 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.0 0.4 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 0.7 PID TNF PATHWAY TNF receptor signaling pathway
0.0 0.5 PID P53 REGULATION PATHWAY p53 pathway
0.0 0.5 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.0 0.1 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 0.4 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.0 0.3 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 0.5 PID IL2 1PATHWAY IL2-mediated signaling events
0.0 1.3 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 0.5 PID LYSOPHOSPHOLIPID PATHWAY LPA receptor mediated events
0.0 0.6 PID LKB1 PATHWAY LKB1 signaling events
0.0 0.5 PID PLK1 PATHWAY PLK1 signaling events
0.0 0.5 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 0.3 SIG BCR SIGNALING PATHWAY Members of the BCR signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.2 1.9 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.1 0.8 REACTOME INTEGRATION OF PROVIRUS Genes involved in Integration of provirus
0.1 1.5 REACTOME KINESINS Genes involved in Kinesins
0.1 1.2 REACTOME ELONGATION ARREST AND RECOVERY Genes involved in Elongation arrest and recovery
0.1 1.4 REACTOME REGULATORY RNA PATHWAYS Genes involved in Regulatory RNA pathways
0.1 1.0 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.1 0.9 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.1 0.5 REACTOME ARMS MEDIATED ACTIVATION Genes involved in ARMS-mediated activation
0.1 1.1 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.1 0.5 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling
0.1 0.9 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.1 0.9 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.9 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.4 REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL Genes involved in NF-kB is activated and signals survival
0.0 0.6 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.5 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.0 1.1 REACTOME SIGNAL TRANSDUCTION BY L1 Genes involved in Signal transduction by L1
0.0 0.7 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.4 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 2.4 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 1.3 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.9 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.0 0.5 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.0 0.6 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.3 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 0.4 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.0 0.5 REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1 Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.0 0.0 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.0 0.5 REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX Genes involved in Activation of the pre-replicative complex
0.0 0.5 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.0 0.3 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 0.2 REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.0 0.7 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.3 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0 0.3 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 0.3 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 0.2 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0 0.3 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.0 0.7 REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS Genes involved in Glycerophospholipid biosynthesis