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avrg: NHBE cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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ISMARA results avrg: NHBE cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

ISMARA - Integrated System for Motif Actitivity Response Analysis is a free online tool that recognizes most important transcription factors that are changing their activity in a set of samples.

Original results

Sample Condition
SARS004-CoV2-1_S401_SARS-CoV-2_infected_NHBE
SARS004-CoV2-2_S501_SARS-CoV-2_infected_NHBE
SARS004-CoV2-3_S601_SARS-CoV-2_infected_NHBE
SARS004-mock-1_S102_mock_NHBE
SARS004-mock-2_S202_mock_NHBE
SARS004-mock-3_S302_mock_NHBE

All motifs sorted by activity significance

Motif name Z-value Associated genes Profile Logo
IRF2_STAT2_IRF8_IRF1 6.42 small profile SeqLogo of IRF2_STAT2_IRF8_IRF1
RELA 6.19 small profile SeqLogo of RELA
IRF9 4.87 small profile SeqLogo of IRF9
IRF6_IRF4_IRF5 3.69 small profile SeqLogo of IRF6_IRF4_IRF5
YBX1_FOS_NFYC_NFYA_NFYB_CEBPZ 3.65 small profile SeqLogo of YBX1_FOS_NFYC_NFYA_NFYB_CEBPZ
REL 3.54 small profile SeqLogo of REL
CEBPA 3.45 small profile SeqLogo of CEBPA
NFKB1 3.33 small profile SeqLogo of NFKB1
CEBPG 3.33 small profile SeqLogo of CEBPG
KLF14_SP8 3.08 small profile SeqLogo of KLF14_SP8
TBP 3.07 small profile SeqLogo of TBP
ELK4_ETV5_ELK1_ELK3_ELF4 2.79 small profile SeqLogo of ELK4_ETV5_ELK1_ELK3_ELF4
ZNF711_TFAP2A_TFAP2D 2.74 small profile SeqLogo of ZNF711_TFAP2A_TFAP2D
FOSL1 2.54 small profile SeqLogo of FOSL1
ID4_TCF4_SNAI2 2.52 small profile SeqLogo of ID4_TCF4_SNAI2
E2F7_E2F1 2.44 small profile SeqLogo of E2F7_E2F1
CEBPE_CEBPD 2.39 small profile SeqLogo of CEBPE_CEBPD
RFX3_RFX2 2.35 small profile SeqLogo of RFX3_RFX2
RELB 2.35 small profile SeqLogo of RELB
IKZF1 2.29 small profile SeqLogo of IKZF1
ZNF384 2.28 small profile SeqLogo of ZNF384
TFCP2 2.26 small profile SeqLogo of TFCP2
POU3F2 2.17 small profile SeqLogo of POU3F2
NFKB2 2.16 small profile SeqLogo of NFKB2
ETS1 2.13 small profile SeqLogo of ETS1
JUN 2.01 small profile SeqLogo of JUN
PBX3 1.96 small profile SeqLogo of PBX3
FOXD3_FOXI1_FOXF1 1.92 small profile SeqLogo of FOXD3_FOXI1_FOXF1
HIVEP1 1.92 small profile SeqLogo of HIVEP1
ETV6 1.87 small profile SeqLogo of ETV6
ZBTB33_CHD2 1.87 small profile SeqLogo of ZBTB33_CHD2
SMAD1 1.86 small profile SeqLogo of SMAD1
MXI1_MYC_MYCN 1.85 small profile SeqLogo of MXI1_MYC_MYCN
VSX1 1.82 small profile SeqLogo of VSX1
GLI3 1.79 small profile SeqLogo of GLI3
AAGGCAC 1.76 small profile SeqLogo of AAGGCAC
HOXB6_PRRX2 1.74 small profile SeqLogo of HOXB6_PRRX2
HMX1 1.74 small profile SeqLogo of HMX1
BACH1_NFE2_NFE2L2 1.72 small profile SeqLogo of BACH1_NFE2_NFE2L2
MAFB 1.69 small profile SeqLogo of MAFB
PPARA 1.69 small profile SeqLogo of PPARA
ETV1_ERF_FEV_ELF1 1.69 small profile SeqLogo of ETV1_ERF_FEV_ELF1
KLF3 1.66 small profile SeqLogo of KLF3
GATA3 1.65 small profile SeqLogo of GATA3
SPIB 1.65 small profile SeqLogo of SPIB
GFI1B 1.65 small profile SeqLogo of GFI1B
ERG 1.63 small profile SeqLogo of ERG
FOXK1_FOXP2_FOXB1_FOXP3 1.62 small profile SeqLogo of FOXK1_FOXP2_FOXB1_FOXP3
HMGA1 1.60 small profile SeqLogo of HMGA1
NR5A2 1.59 small profile SeqLogo of NR5A2
RXRG 1.53 small profile SeqLogo of RXRG
MYF6 1.51 small profile SeqLogo of MYF6
MAFK 1.51 small profile SeqLogo of MAFK
RAD21_SMC3 1.50 small profile SeqLogo of RAD21_SMC3
IRX5 1.48 small profile SeqLogo of IRX5
TAF1 1.46 small profile SeqLogo of TAF1
RARB 1.46 small profile SeqLogo of RARB
NFATC2_NFATC3 1.45 small profile SeqLogo of NFATC2_NFATC3
MBD2 1.44 small profile SeqLogo of MBD2
E2F2_E2F5 1.44 small profile SeqLogo of E2F2_E2F5
NR2E3 1.43 small profile SeqLogo of NR2E3
DBP 1.42 small profile SeqLogo of DBP
CEBPB 1.42 small profile SeqLogo of CEBPB
EZH2 1.41 small profile SeqLogo of EZH2
HOXC9 1.41 small profile SeqLogo of HOXC9
TBX4 1.40 small profile SeqLogo of TBX4
MYB 1.40 small profile SeqLogo of MYB
NKX2-4 1.38 small profile SeqLogo of NKX2-4
KLF1 1.38 small profile SeqLogo of KLF1
MLXIPL 1.37 small profile SeqLogo of MLXIPL
ESRRA_ESR2 1.37 small profile SeqLogo of ESRRA_ESR2
FOXN1 1.37 small profile SeqLogo of FOXN1
GMEB2 1.36 small profile SeqLogo of GMEB2
ETV4_ETS2 1.36 small profile SeqLogo of ETV4_ETS2
HOXC11 1.36 small profile SeqLogo of HOXC11
TP63 1.35 small profile SeqLogo of TP63
PITX3 1.35 small profile SeqLogo of PITX3
TBX1 1.34 small profile SeqLogo of TBX1
ATF7 1.33 small profile SeqLogo of ATF7
HOXC13 1.33 small profile SeqLogo of HOXC13
HNF4A 1.30 small profile SeqLogo of HNF4A
MIXL1_GSX1_BSX_MEOX2_LHX4 1.30 small profile SeqLogo of MIXL1_GSX1_BSX_MEOX2_LHX4
NKX6-2 1.30 small profile SeqLogo of NKX6-2
BARHL1 1.29 small profile SeqLogo of BARHL1
AAAGUGC 1.28 small profile SeqLogo of AAAGUGC
CUUUGGU 1.27 small profile SeqLogo of CUUUGGU
MLX_USF2_USF1_PAX2 1.27 small profile SeqLogo of MLX_USF2_USF1_PAX2
MAFF_MAFG 1.27 small profile SeqLogo of MAFF_MAFG
SPI1 1.26 small profile SeqLogo of SPI1
SIN3A_CHD1 1.25 small profile SeqLogo of SIN3A_CHD1
PATZ1_KLF4 1.25 small profile SeqLogo of PATZ1_KLF4
NRF1 1.24 small profile SeqLogo of NRF1
NHLH1 1.24 small profile SeqLogo of NHLH1
TBX19 1.24 small profile SeqLogo of TBX19
TCF21 1.23 small profile SeqLogo of TCF21
HIF1A 1.22 small profile SeqLogo of HIF1A
UUGGCAA 1.22 small profile SeqLogo of UUGGCAA
FOXL1 1.21 small profile SeqLogo of FOXL1
LHX6 1.21 small profile SeqLogo of LHX6
RXRA_NR2F6_NR2C2 1.20 small profile SeqLogo of RXRA_NR2F6_NR2C2
GUGCAAA 1.20 small profile SeqLogo of GUGCAAA
XBP1 1.18 small profile SeqLogo of XBP1
BATF 1.17 small profile SeqLogo of BATF
HMX3 1.16 small profile SeqLogo of HMX3
RORA 1.15 small profile SeqLogo of RORA
MYBL2 1.14 small profile SeqLogo of MYBL2
UACAGUA 1.13 small profile SeqLogo of UACAGUA
TCF3_MYOG 1.12 small profile SeqLogo of TCF3_MYOG
IRF3 1.12 small profile SeqLogo of IRF3
NR1I2 1.10 small profile SeqLogo of NR1I2
HES1 1.10 small profile SeqLogo of HES1
NR2F2 1.10 small profile SeqLogo of NR2F2
ELF2_GABPA_ELF5 1.09 small profile SeqLogo of ELF2_GABPA_ELF5
TGIF1 1.08 small profile SeqLogo of TGIF1
LEF1 1.08 small profile SeqLogo of LEF1
MAZ_ZNF281_GTF2F1 1.07 small profile SeqLogo of MAZ_ZNF281_GTF2F1
ARID3A 1.07 small profile SeqLogo of ARID3A
RUNX3_BCL11A 1.07 small profile SeqLogo of RUNX3_BCL11A
GMEB1 1.06 small profile SeqLogo of GMEB1
EP300 1.06 small profile SeqLogo of EP300
NANOG 1.05 small profile SeqLogo of NANOG
TBX3 1.05 small profile SeqLogo of TBX3
PAX8 1.04 small profile SeqLogo of PAX8
NR3C1 1.04 small profile SeqLogo of NR3C1
CREB3L2 1.03 small profile SeqLogo of CREB3L2
GUAAACA 1.02 small profile SeqLogo of GUAAACA
ZSCAN4 1.02 small profile SeqLogo of ZSCAN4
HOXB3 0.99 small profile SeqLogo of HOXB3
STAT5B 0.98 small profile SeqLogo of STAT5B
EMX2 0.98 small profile SeqLogo of EMX2
KLF15 0.97 small profile SeqLogo of KLF15
FOXD1_FOXO1_FOXO6_FOXG1_FOXP1 0.95 small profile SeqLogo of FOXD1_FOXO1_FOXO6_FOXG1_FOXP1
ZNF784 0.95 small profile SeqLogo of ZNF784
NKX2-8 0.94 small profile SeqLogo of NKX2-8
HLF_TEF 0.93 small profile SeqLogo of HLF_TEF
FOXA1 0.92 small profile SeqLogo of FOXA1
BPTF 0.92 small profile SeqLogo of BPTF
E2F6 0.91 small profile SeqLogo of E2F6
EMX1 0.91 small profile SeqLogo of EMX1
SPDEF 0.91 small profile SeqLogo of SPDEF
AACACUG 0.90 small profile SeqLogo of AACACUG
HIC2 0.89 small profile SeqLogo of HIC2
TFAP2C 0.89 small profile SeqLogo of TFAP2C
HBP1 0.88 small profile SeqLogo of HBP1
SOX9 0.88 small profile SeqLogo of SOX9
NR4A2 0.88 small profile SeqLogo of NR4A2
UAAGGCA 0.88 small profile SeqLogo of UAAGGCA
PKNOX1_TGIF2 0.87 small profile SeqLogo of PKNOX1_TGIF2
WRNIP1 0.87 small profile SeqLogo of WRNIP1
SRF 0.87 small profile SeqLogo of SRF
AAUACUG 0.87 small profile SeqLogo of AAUACUG
RBPJ 0.86 small profile SeqLogo of RBPJ
PDX1 0.86 small profile SeqLogo of PDX1
SOX5 0.86 small profile SeqLogo of SOX5
CPEB1 0.85 small profile SeqLogo of CPEB1
HOMEZ 0.85 small profile SeqLogo of HOMEZ
DUXA 0.85 small profile SeqLogo of DUXA
OTX1 0.85 small profile SeqLogo of OTX1
POU5F1_POU2F3 0.85 small profile SeqLogo of POU5F1_POU2F3
TFEC_MITF_ARNTL_BHLHE41 0.84 small profile SeqLogo of TFEC_MITF_ARNTL_BHLHE41
RCOR1_MTA3 0.84 small profile SeqLogo of RCOR1_MTA3
HAND1 0.84 small profile SeqLogo of HAND1
PITX1 0.84 small profile SeqLogo of PITX1
ELF3_EHF 0.84 small profile SeqLogo of ELF3_EHF
SOX13_SOX12 0.83 small profile SeqLogo of SOX13_SOX12
SCRT1_SCRT2 0.83 small profile SeqLogo of SCRT1_SCRT2
TWIST1_SNAI1 0.83 small profile SeqLogo of TWIST1_SNAI1
BCL6B 0.82 small profile SeqLogo of BCL6B
MYBL1 0.82 small profile SeqLogo of MYBL1
EN1_ESX1_GBX1 0.82 small profile SeqLogo of EN1_ESX1_GBX1
OLIG2_NEUROD1_ATOH1 0.82 small profile SeqLogo of OLIG2_NEUROD1_ATOH1
NR0B1 0.82 small profile SeqLogo of NR0B1
NKX2-2 0.81 small profile SeqLogo of NKX2-2
TFDP1 0.81 small profile SeqLogo of TFDP1
AUUGCAC 0.81 small profile SeqLogo of AUUGCAC
UGCAUAG 0.80 small profile SeqLogo of UGCAUAG
DDIT3 0.80 small profile SeqLogo of DDIT3
KLF6 0.80 small profile SeqLogo of KLF6
SMAD4 0.80 small profile SeqLogo of SMAD4
UCACAUU 0.79 small profile SeqLogo of UCACAUU
HOXD9 0.79 small profile SeqLogo of HOXD9
INSM1 0.78 small profile SeqLogo of INSM1
SOX7 0.77 small profile SeqLogo of SOX7
TFAP4_MSC 0.76 small profile SeqLogo of TFAP4_MSC
RFX7_RFX4_RFX1 0.76 small profile SeqLogo of RFX7_RFX4_RFX1
HOXC10_HOXD13 0.76 small profile SeqLogo of HOXC10_HOXD13
ISX 0.75 small profile SeqLogo of ISX
NFATC1 0.75 small profile SeqLogo of NFATC1
AGGUAGU 0.75 small profile SeqLogo of AGGUAGU
UCCAGUU 0.74 small profile SeqLogo of UCCAGUU
SOX8 0.74 small profile SeqLogo of SOX8
DBX2_HLX 0.74 small profile SeqLogo of DBX2_HLX
SP1 0.74 small profile SeqLogo of SP1
HDX 0.73 small profile SeqLogo of HDX
MEF2C 0.73 small profile SeqLogo of MEF2C
GGAAUGU 0.72 small profile SeqLogo of GGAAUGU
PPARG 0.72 small profile SeqLogo of PPARG
CXXC1 0.72 small profile SeqLogo of CXXC1
IRF7 0.71 small profile SeqLogo of IRF7
FOXC1 0.71 small profile SeqLogo of FOXC1
POU2F2_POU3F1 0.71 small profile SeqLogo of POU2F2_POU3F1
IRX3 0.71 small profile SeqLogo of IRX3
HSF1 0.70 small profile SeqLogo of HSF1
FOXA3_FOXC2 0.70 small profile SeqLogo of FOXA3_FOXC2
GAUUGUC 0.69 small profile SeqLogo of GAUUGUC
ZIC1 0.69 small profile SeqLogo of ZIC1
EBF1 0.69 small profile SeqLogo of EBF1
UUGGCAC 0.68 small profile SeqLogo of UUGGCAC
ARID5A 0.68 small profile SeqLogo of ARID5A
POU2F1 0.68 small profile SeqLogo of POU2F1
IRX2 0.67 small profile SeqLogo of IRX2
HOXB8 0.67 small profile SeqLogo of HOXB8
HOXA13 0.67 small profile SeqLogo of HOXA13
EBF3 0.67 small profile SeqLogo of EBF3
IKZF2 0.67 small profile SeqLogo of IKZF2
RUNX1_RUNX2 0.66 small profile SeqLogo of RUNX1_RUNX2
ZNF148 0.66 small profile SeqLogo of ZNF148
GCAGCAU 0.66 small profile SeqLogo of GCAGCAU
ZIC3_ZIC4 0.66 small profile SeqLogo of ZIC3_ZIC4
LHX8 0.66 small profile SeqLogo of LHX8
ZNF232 0.66 small profile SeqLogo of ZNF232
RARA 0.66 small profile SeqLogo of RARA
E2F3 0.66 small profile SeqLogo of E2F3
MEIS3_TGIF2LX 0.65 small profile SeqLogo of MEIS3_TGIF2LX
GATA1_GATA4 0.65 small profile SeqLogo of GATA1_GATA4
E2F4 0.65 small profile SeqLogo of E2F4
HMBOX1 0.65 small profile SeqLogo of HMBOX1
GATA6 0.65 small profile SeqLogo of GATA6
T 0.64 small profile SeqLogo of T
ESRRB_ESRRG 0.64 small profile SeqLogo of ESRRB_ESRRG
ACAGUAC 0.63 small profile SeqLogo of ACAGUAC
UGUGCUU 0.63 small profile SeqLogo of UGUGCUU
GAGGUAG 0.63 small profile SeqLogo of GAGGUAG
ZBTB12 0.63 small profile SeqLogo of ZBTB12
AUGGCAC 0.63 small profile SeqLogo of AUGGCAC
PRDM1 0.62 small profile SeqLogo of PRDM1
POU4F2 0.62 small profile SeqLogo of POU4F2
AGUGCAA 0.62 small profile SeqLogo of AGUGCAA
HNF1A_HNF1B 0.62 small profile SeqLogo of HNF1A_HNF1B
DLX4_HOXD8 0.62 small profile SeqLogo of DLX4_HOXD8
WT1_MTF1_ZBTB7B 0.61 small profile SeqLogo of WT1_MTF1_ZBTB7B
DPRX 0.61 small profile SeqLogo of DPRX
NKX2-3 0.61 small profile SeqLogo of NKX2-3
MEF2B 0.60 small profile SeqLogo of MEF2B
ZNF143 0.60 small profile SeqLogo of ZNF143
ZNF740_ZNF219 0.60 small profile SeqLogo of ZNF740_ZNF219
PAX3 0.60 small profile SeqLogo of PAX3
TBX21_TBR1 0.60 small profile SeqLogo of TBX21_TBR1
POU3F3_POU3F4 0.60 small profile SeqLogo of POU3F3_POU3F4
NKX2-1 0.60 small profile SeqLogo of NKX2-1
IRX6_IRX4 0.59 small profile SeqLogo of IRX6_IRX4
HOXA2_HOXB1 0.59 small profile SeqLogo of HOXA2_HOXB1
PPARD 0.59 small profile SeqLogo of PPARD
GLIS2 0.59 small profile SeqLogo of GLIS2
CACAGUG 0.59 small profile SeqLogo of CACAGUG
ZBTB14 0.59 small profile SeqLogo of ZBTB14
HMGA2 0.59 small profile SeqLogo of HMGA2
SIX6