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avrg: NHBE cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for NKX6-3

Z-value: 0.28

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Transcription factors associated with NKX6-3

Gene Symbol Gene ID Gene Info
ENSG00000165066.11 NKX6-3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NKX6-3hg19_v2_chr8_-_41508855_41508855-0.721.0e-01Click!

Activity profile of NKX6-3 motif

Sorted Z-values of NKX6-3 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of NKX6-3

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr8_-_90769422 0.15 ENST00000524190.1
ENST00000523859.1
RP11-37B2.1
RP11-37B2.1
chr5_-_139726181 0.12 ENST00000507104.1
ENST00000230990.6
HBEGF
heparin-binding EGF-like growth factor
chr3_+_138340067 0.09 ENST00000479848.1
FAIM
Fas apoptotic inhibitory molecule
chr14_-_51027838 0.09 ENST00000555216.1
MAP4K5
mitogen-activated protein kinase kinase kinase kinase 5
chr17_+_4692230 0.08 ENST00000331264.7
GLTPD2
glycolipid transfer protein domain containing 2
chr2_-_44550441 0.08 ENST00000420756.1
ENST00000444696.1
PREPL
prolyl endopeptidase-like
chr18_+_32558380 0.07 ENST00000588349.2
MAPRE2
microtubule-associated protein, RP/EB family, member 2
chr9_+_125133315 0.06 ENST00000223423.4
ENST00000362012.2
PTGS1
prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
chrX_+_43515467 0.06 ENST00000338702.3
ENST00000542639.1
MAOA
monoamine oxidase A
chr9_+_125133467 0.06 ENST00000426608.1
PTGS1
prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
chr14_+_67831576 0.05 ENST00000555876.1
EIF2S1
eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa
chr3_+_136649311 0.05 ENST00000469404.1
ENST00000467911.1
NCK1
NCK adaptor protein 1
chr4_+_80584903 0.04 ENST00000506460.1
RP11-452C8.1
RP11-452C8.1
chr3_+_138340049 0.04 ENST00000464668.1
FAIM
Fas apoptotic inhibitory molecule
chr6_+_114178512 0.03 ENST00000368635.4
MARCKS
myristoylated alanine-rich protein kinase C substrate
chr15_+_90735145 0.03 ENST00000559792.1
SEMA4B
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B
chrX_+_107288239 0.03 ENST00000217957.5
VSIG1
V-set and immunoglobulin domain containing 1
chr14_+_88852059 0.02 ENST00000045347.7
SPATA7
spermatogenesis associated 7
chr20_-_33735070 0.02 ENST00000374491.3
ENST00000542871.1
ENST00000374492.3
EDEM2
ER degradation enhancer, mannosidase alpha-like 2
chrX_+_107288197 0.02 ENST00000415430.3
VSIG1
V-set and immunoglobulin domain containing 1
chr9_+_125132803 0.02 ENST00000540753.1
PTGS1
prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
chr1_-_232651312 0.02 ENST00000262861.4
SIPA1L2
signal-induced proliferation-associated 1 like 2
chr5_-_58295712 0.02 ENST00000317118.8
PDE4D
phosphodiesterase 4D, cAMP-specific
chr15_+_48051920 0.02 ENST00000559196.1
SEMA6D
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D
chr8_+_92261516 0.02 ENST00000276609.3
ENST00000309536.2
SLC26A7
solute carrier family 26 (anion exchanger), member 7
chr9_-_215744 0.02 ENST00000382387.2
C9orf66
chromosome 9 open reading frame 66
chr4_+_71384300 0.02 ENST00000504451.1
AMTN
amelotin
chr10_-_27529486 0.01 ENST00000375888.1
ACBD5
acyl-CoA binding domain containing 5
chr13_-_81801115 0.01 ENST00000567258.1
LINC00564
long intergenic non-protein coding RNA 564
chrX_+_47696275 0.01 ENST00000376954.1
ENST00000338637.7
ZNF81
zinc finger protein 81
chr5_-_142780280 0.01 ENST00000424646.2
NR3C1
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
chr12_-_94673956 0.01 ENST00000551941.1
RP11-1105G2.3
Uncharacterized protein
chr18_+_20494078 0.01 ENST00000579124.1
ENST00000577588.1
ENST00000582354.1
ENST00000581819.1
RBBP8
retinoblastoma binding protein 8
chr8_+_77593474 0.01 ENST00000455469.2
ENST00000050961.6
ZFHX4
zinc finger homeobox 4
chr15_+_93443419 0.01 ENST00000557381.1
ENST00000420239.2
CHD2
chromodomain helicase DNA binding protein 2
chrX_+_107288280 0.00 ENST00000458383.1
VSIG1
V-set and immunoglobulin domain containing 1
chr3_+_121902511 0.00 ENST00000490131.1
CASR
calcium-sensing receptor
chr11_+_22689648 0.00 ENST00000278187.3
GAS2
growth arrest-specific 2
chr19_-_6057282 0.00 ENST00000592281.1
RFX2
regulatory factor X, 2 (influences HLA class II expression)
chrX_-_110655306 0.00 ENST00000371993.2
DCX
doublecortin

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0051541 elastin metabolic process(GO:0051541)
0.0 0.0 GO:1903676 regulation of cap-dependent translational initiation(GO:1903674) positive regulation of cap-dependent translational initiation(GO:1903676)
0.0 0.1 GO:1990737 response to manganese-induced endoplasmic reticulum stress(GO:1990737)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0043614 multi-eIF complex(GO:0043614) translation preinitiation complex(GO:0070993)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)