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avrg: NHBE cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for TP73

Z-value: 0.02

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Transcription factors associated with TP73

Gene Symbol Gene ID Gene Info
ENSG00000078900.10 TP73

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
TP73hg19_v2_chr1_+_3569072_35690930.862.7e-02Click!

Activity profile of TP73 motif

Sorted Z-values of TP73 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of TP73

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr19_+_10654854 0.11 ENST00000586477.1
ENST00000586863.1
ATG4D
autophagy related 4D, cysteine peptidase
chr19_+_17326521 0.09 ENST00000593597.1
USE1
unconventional SNARE in the ER 1 homolog (S. cerevisiae)
chr11_+_65686952 0.09 ENST00000527119.1
DRAP1
DR1-associated protein 1 (negative cofactor 2 alpha)
chr19_+_41856816 0.08 ENST00000539627.1
TMEM91
transmembrane protein 91
chr17_+_73750699 0.08 ENST00000584939.1
ITGB4
integrin, beta 4
chr3_-_50340996 0.07 ENST00000266031.4
ENST00000395143.2
ENST00000457214.2
ENST00000447605.2
ENST00000418723.1
ENST00000395144.2
HYAL1
hyaluronoglucosaminidase 1
chr8_-_145016692 0.07 ENST00000357649.2
PLEC
plectin
chr19_+_45254529 0.05 ENST00000444487.1
BCL3
B-cell CLL/lymphoma 3
chr16_+_67197288 0.05 ENST00000264009.8
ENST00000421453.1
HSF4
heat shock transcription factor 4
chr11_+_65154070 0.05 ENST00000317568.5
ENST00000531296.1
ENST00000533782.1
ENST00000355991.5
ENST00000416776.2
ENST00000526201.1
FRMD8
FERM domain containing 8
chr18_+_77623668 0.05 ENST00000316249.3
KCNG2
potassium voltage-gated channel, subfamily G, member 2
chr14_+_96858454 0.05 ENST00000555570.1
AK7
adenylate kinase 7
chr3_-_48936272 0.05 ENST00000544097.1
ENST00000430379.1
ENST00000319017.4
SLC25A20
solute carrier family 25 (carnitine/acylcarnitine translocase), member 20
chr17_+_4835580 0.04 ENST00000329125.5
GP1BA
glycoprotein Ib (platelet), alpha polypeptide
chr11_+_65687158 0.04 ENST00000532933.1
DRAP1
DR1-associated protein 1 (negative cofactor 2 alpha)
chr19_-_35981358 0.04 ENST00000484218.2
ENST00000338897.3
KRTDAP
keratinocyte differentiation-associated protein
chr14_+_75745477 0.04 ENST00000303562.4
ENST00000554617.1
ENST00000554212.1
ENST00000535987.1
ENST00000555242.1
FOS
FBJ murine osteosarcoma viral oncogene homolog
chr4_+_6717842 0.04 ENST00000320776.3
BLOC1S4
biogenesis of lysosomal organelles complex-1, subunit 4, cappuccino
chr12_-_117319236 0.04 ENST00000257572.5
HRK
harakiri, BCL2 interacting protein (contains only BH3 domain)
chr17_+_37356528 0.04 ENST00000225430.4
RPL19
ribosomal protein L19
chr17_-_2615031 0.04 ENST00000576885.1
ENST00000574426.2
CLUH
clustered mitochondria (cluA/CLU1) homolog
chr6_+_31515337 0.03 ENST00000376148.4
ENST00000376145.4
NFKBIL1
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
chr17_-_42200996 0.03 ENST00000587135.1
ENST00000225983.6
ENST00000393622.2
ENST00000588703.1
HDAC5
histone deacetylase 5
chr15_+_64680003 0.03 ENST00000261884.3
TRIP4
thyroid hormone receptor interactor 4
chr15_+_75498739 0.03 ENST00000565074.1
C15orf39
chromosome 15 open reading frame 39
chr17_+_78388959 0.03 ENST00000518137.1
ENST00000520367.1
ENST00000523999.1
ENST00000323854.5
ENST00000522751.1
ENDOV
endonuclease V
chr15_+_75498355 0.03 ENST00000567617.1
C15orf39
chromosome 15 open reading frame 39
chr17_+_37356555 0.03 ENST00000579374.1
RPL19
ribosomal protein L19
chr14_-_105531759 0.03 ENST00000329797.3
ENST00000539291.2
ENST00000392585.2
GPR132
G protein-coupled receptor 132
chr2_-_27357479 0.03 ENST00000406567.3
ENST00000260643.2
PREB
prolactin regulatory element binding
chr15_-_74043816 0.03 ENST00000379822.4
C15orf59
chromosome 15 open reading frame 59
chr2_+_95940220 0.03 ENST00000542147.1
PROM2
prominin 2
chr12_+_102271436 0.03 ENST00000544152.1
DRAM1
DNA-damage regulated autophagy modulator 1
chr19_-_19626838 0.03 ENST00000360913.3
TSSK6
testis-specific serine kinase 6
chr20_-_62203808 0.03 ENST00000467148.1
HELZ2
helicase with zinc finger 2, transcriptional coactivator
chr2_-_26205550 0.03 ENST00000405914.1
KIF3C
kinesin family member 3C
chr17_-_47492236 0.03 ENST00000434917.2
ENST00000300408.3
ENST00000511832.1
ENST00000419140.2
PHB
prohibitin
chr17_-_2614927 0.02 ENST00000435359.1
CLUH
clustered mitochondria (cluA/CLU1) homolog
chr22_-_39150947 0.02 ENST00000411587.2
ENST00000420859.1
ENST00000452294.1
ENST00000456894.1
SUN2
Sad1 and UNC84 domain containing 2
chr9_+_36169380 0.02 ENST00000335119.2
CCIN
calicin
chr12_-_82752159 0.02 ENST00000552377.1
CCDC59
coiled-coil domain containing 59
chr19_+_44037546 0.02 ENST00000601282.1
ZNF575
zinc finger protein 575
chr6_-_72130472 0.02 ENST00000426635.2
LINC00472
long intergenic non-protein coding RNA 472
chr5_+_125759140 0.02 ENST00000543198.1
GRAMD3
GRAM domain containing 3
chr16_+_75032901 0.02 ENST00000335325.4
ENST00000320619.6
ZNRF1
zinc and ring finger 1, E3 ubiquitin protein ligase
chr9_-_138391692 0.02 ENST00000429260.2
C9orf116
chromosome 9 open reading frame 116
chr6_-_33256664 0.02 ENST00000444176.1
WDR46
WD repeat domain 46
chr22_-_20255212 0.02 ENST00000416372.1
RTN4R
reticulon 4 receptor
chr16_-_8891481 0.02 ENST00000333050.6
TMEM186
transmembrane protein 186
chr11_+_75479850 0.02 ENST00000376262.3
ENST00000604733.1
DGAT2
diacylglycerol O-acyltransferase 2
chr12_-_91573249 0.02 ENST00000550099.1
ENST00000546391.1
ENST00000551354.1
DCN
decorin
chr17_-_79818354 0.02 ENST00000576541.1
ENST00000576380.1
ENST00000571617.1
ENST00000576052.1
ENST00000576390.1
ENST00000573778.2
ENST00000439918.2
ENST00000574914.1
ENST00000331483.4
P4HB
prolyl 4-hydroxylase, beta polypeptide
chr19_+_41620335 0.02 ENST00000331105.2
CYP2F1
cytochrome P450, family 2, subfamily F, polypeptide 1
chr14_-_75078725 0.02 ENST00000556690.1
LTBP2
latent transforming growth factor beta binding protein 2
chr7_-_128045984 0.02 ENST00000470772.1
ENST00000480861.1
ENST00000496200.1
IMPDH1
IMP (inosine 5'-monophosphate) dehydrogenase 1
chr22_+_39966758 0.02 ENST00000407673.1
ENST00000401624.1
ENST00000404898.1
ENST00000402142.3
ENST00000336649.4
ENST00000400164.3
CACNA1I
calcium channel, voltage-dependent, T type, alpha 1I subunit
chr9_+_138391805 0.02 ENST00000371785.1
MRPS2
mitochondrial ribosomal protein S2
chr15_+_41136369 0.02 ENST00000563656.1
SPINT1
serine peptidase inhibitor, Kunitz type 1
chr19_+_19627026 0.02 ENST00000608404.1
ENST00000555938.1
ENST00000503283.1
ENST00000512771.3
ENST00000428459.2
YJEFN3
CTC-260F20.3
NDUFA13
YjeF N-terminal domain containing 3
Uncharacterized protein
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 13
chr8_+_145065705 0.02 ENST00000533044.1
GRINA
glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding)
chr8_+_63161550 0.02 ENST00000328472.5
NKAIN3
Na+/K+ transporting ATPase interacting 3
chr19_+_49622646 0.02 ENST00000334186.4
PPFIA3
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3
chr3_+_48481658 0.02 ENST00000438607.2
TMA7
translation machinery associated 7 homolog (S. cerevisiae)
chr17_+_43318434 0.02 ENST00000587489.1
FMNL1
formin-like 1
chr17_+_72427477 0.02 ENST00000342648.5
ENST00000481232.1
GPRC5C
G protein-coupled receptor, family C, group 5, member C
chr19_+_35596873 0.02 ENST00000313865.6
AC020907.1
Uncharacterized protein
chr15_+_57891609 0.01 ENST00000569089.1
MYZAP
myocardial zonula adherens protein
chr18_-_53253000 0.01 ENST00000566514.1
TCF4
transcription factor 4
chr19_+_45281118 0.01 ENST00000270279.3
ENST00000341505.4
CBLC
Cbl proto-oncogene C, E3 ubiquitin protein ligase
chr7_-_27213893 0.01 ENST00000283921.4
HOXA10
homeobox A10
chr3_-_151160938 0.01 ENST00000489791.1
IGSF10
immunoglobulin superfamily, member 10
chr11_+_236540 0.01 ENST00000532097.1
PSMD13
proteasome (prosome, macropain) 26S subunit, non-ATPase, 13
chr11_-_75062829 0.01 ENST00000393505.4
ARRB1
arrestin, beta 1
chr1_-_26197744 0.01 ENST00000374296.3
PAQR7
progestin and adipoQ receptor family member VII
chr14_+_52780998 0.01 ENST00000557436.1
PTGER2
prostaglandin E receptor 2 (subtype EP2), 53kDa
chr13_-_48877795 0.01 ENST00000436963.1
ENST00000433480.2
LINC00441
long intergenic non-protein coding RNA 441
chr7_-_2883928 0.01 ENST00000275364.3
GNA12
guanine nucleotide binding protein (G protein) alpha 12
chr17_+_37356586 0.01 ENST00000579260.1
ENST00000582193.1
RPL19
ribosomal protein L19
chr14_+_105935396 0.01 ENST00000494981.1
MTA1
metastasis associated 1
chr7_-_100171270 0.01 ENST00000538735.1
SAP25
Sin3A-associated protein, 25kDa
chr11_-_65686496 0.01 ENST00000449692.3
C11orf68
chromosome 11 open reading frame 68
chr6_+_155537771 0.01 ENST00000275246.7
TIAM2
T-cell lymphoma invasion and metastasis 2
chr17_+_21191341 0.01 ENST00000526076.2
ENST00000361818.5
ENST00000316920.6
MAP2K3
mitogen-activated protein kinase kinase 3
chr9_+_6758024 0.01 ENST00000442236.2
KDM4C
lysine (K)-specific demethylase 4C
chr17_-_47492164 0.01 ENST00000512041.2
ENST00000446735.1
ENST00000504124.1
PHB
prohibitin
chr17_-_28661065 0.01 ENST00000328886.4
ENST00000538566.2
TMIGD1
transmembrane and immunoglobulin domain containing 1
chr15_+_41136216 0.01 ENST00000562057.1
ENST00000344051.4
SPINT1
serine peptidase inhibitor, Kunitz type 1
chr8_+_37654424 0.01 ENST00000315215.7
GPR124
G protein-coupled receptor 124
chr16_-_68000717 0.01 ENST00000541864.2
SLC12A4
solute carrier family 12 (potassium/chloride transporter), member 4
chr16_+_8891670 0.01 ENST00000268261.4
ENST00000539622.1
ENST00000569958.1
ENST00000537352.1
PMM2
phosphomannomutase 2
chr18_-_4455260 0.01 ENST00000581527.1
DLGAP1
discs, large (Drosophila) homolog-associated protein 1
chr1_-_78444776 0.01 ENST00000370767.1
ENST00000421641.1
FUBP1
far upstream element (FUSE) binding protein 1
chr11_+_63448918 0.01 ENST00000341307.2
ENST00000356000.3
ENST00000542238.1
RTN3
reticulon 3
chrX_+_9880412 0.01 ENST00000418909.2
SHROOM2
shroom family member 2
chr1_-_236228403 0.01 ENST00000366595.3
NID1
nidogen 1
chrX_-_138724994 0.01 ENST00000536274.1
MCF2
MCF.2 cell line derived transforming sequence
chr14_+_75746340 0.01 ENST00000555686.1
ENST00000555672.1
FOS
FBJ murine osteosarcoma viral oncogene homolog
chr10_-_79686284 0.01 ENST00000372391.2
ENST00000372388.2
DLG5
discs, large homolog 5 (Drosophila)
chr6_+_155538093 0.01 ENST00000462408.2
TIAM2
T-cell lymphoma invasion and metastasis 2
chr20_-_52790512 0.01 ENST00000216862.3
CYP24A1
cytochrome P450, family 24, subfamily A, polypeptide 1
chr17_-_40835076 0.01 ENST00000591765.1
CCR10
chemokine (C-C motif) receptor 10
chr2_+_95940186 0.01 ENST00000403131.2
ENST00000317668.4
ENST00000317620.9
PROM2
prominin 2
chr12_-_57505121 0.01 ENST00000538913.2
ENST00000537215.2
ENST00000454075.3
ENST00000554825.1
ENST00000553275.1
ENST00000300134.3
STAT6
signal transducer and activator of transcription 6, interleukin-4 induced
chr17_+_54230819 0.01 ENST00000318698.2
ENST00000566473.2
ANKFN1
ankyrin-repeat and fibronectin type III domain containing 1
chr1_-_78444738 0.00 ENST00000436586.2
ENST00000370768.2
FUBP1
far upstream element (FUSE) binding protein 1
chr15_+_41136586 0.00 ENST00000431806.1
SPINT1
serine peptidase inhibitor, Kunitz type 1
chrX_-_80377118 0.00 ENST00000373250.3
HMGN5
high mobility group nucleosome binding domain 5
chr7_-_2883650 0.00 ENST00000544127.1
GNA12
guanine nucleotide binding protein (G protein) alpha 12
chr9_+_131445703 0.00 ENST00000454747.1
SET
SET nuclear oncogene
chr9_+_6757634 0.00 ENST00000543771.1
ENST00000401787.3
ENST00000381306.3
ENST00000381309.3
KDM4C
lysine (K)-specific demethylase 4C
chr11_+_66234216 0.00 ENST00000349459.6
ENST00000320740.7
ENST00000524466.1
ENST00000526296.1
PELI3
pellino E3 ubiquitin protein ligase family member 3
chr2_-_158485387 0.00 ENST00000243349.8
ACVR1C
activin A receptor, type IC
chr5_+_139027877 0.00 ENST00000302517.3
CXXC5
CXXC finger protein 5
chr17_-_39459103 0.00 ENST00000391353.1
KRTAP29-1
keratin associated protein 29-1
chr3_+_100120441 0.00 ENST00000489752.1
LNP1
leukemia NUP98 fusion partner 1
chr8_+_63161491 0.00 ENST00000523211.1
ENST00000524201.1
NKAIN3
Na+/K+ transporting ATPase interacting 3
chr10_+_47746929 0.00 ENST00000340243.6
ENST00000374277.5
ENST00000449464.2
ENST00000538825.1
ENST00000335083.5
ANXA8L2
AL603965.1
annexin A8-like 2
Protein LOC100996760
chr10_-_47173994 0.00 ENST00000414655.2
ENST00000545298.1
ENST00000359178.4
ENST00000358140.4
ENST00000503031.1
ANXA8L1
LINC00842
annexin A8-like 1
long intergenic non-protein coding RNA 842
chr6_-_112194484 0.00 ENST00000518295.1
ENST00000484067.2
ENST00000229470.5
ENST00000356013.2
ENST00000368678.4
ENST00000523238.1
ENST00000354650.3
FYN
FYN oncogene related to SRC, FGR, YES
chr14_-_25519095 0.00 ENST00000419632.2
ENST00000358326.2
ENST00000396700.1
ENST00000548724.1
STXBP6
syntaxin binding protein 6 (amisyn)
chr2_-_73511559 0.00 ENST00000521871.1
FBXO41
F-box protein 41
chr20_+_48807351 0.00 ENST00000303004.3
CEBPB
CCAAT/enhancer binding protein (C/EBP), beta
chr15_+_41136263 0.00 ENST00000568823.1
SPINT1
serine peptidase inhibitor, Kunitz type 1
chr8_+_37654693 0.00 ENST00000412232.2
GPR124
G protein-coupled receptor 124
chr11_+_63448955 0.00 ENST00000377819.5
ENST00000339997.4
ENST00000540798.1
ENST00000545432.1
ENST00000543552.1
ENST00000537981.1
RTN3
reticulon 3
chr17_-_39023462 0.00 ENST00000251643.4
KRT12
keratin 12
chr9_+_87285257 0.00 ENST00000323115.4
NTRK2
neurotrophic tyrosine kinase, receptor, type 2
chr1_-_236228417 0.00 ENST00000264187.6
NID1
nidogen 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0045082 positive regulation of interleukin-10 biosynthetic process(GO:0045082)
0.0 0.1 GO:0051697 protein delipidation(GO:0051697)
0.0 0.1 GO:1900106 hyaluranon cable assembly(GO:0036118) regulation of hyaluranon cable assembly(GO:1900104) positive regulation of hyaluranon cable assembly(GO:1900106)
0.0 0.0 GO:1902616 acyl carnitine transport(GO:0006844) acyl carnitine transmembrane transport(GO:1902616)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0036117 hyaluranon cable(GO:0036117)
0.0 0.1 GO:0033257 Bcl3/NF-kappaB2 complex(GO:0033257)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
0.0 0.1 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.0 0.0 GO:0015227 amino-acid betaine transmembrane transporter activity(GO:0015199) carnitine transmembrane transporter activity(GO:0015226) acyl carnitine transmembrane transporter activity(GO:0015227)