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avrg: NHBE cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for POU6F1

Z-value: 0.15

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Transcription factors associated with POU6F1

Gene Symbol Gene ID Gene Info
ENSG00000184271.11 POU6F1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
POU6F1hg19_v2_chr12_-_51611477_516116120.059.2e-01Click!

Activity profile of POU6F1 motif

Sorted Z-values of POU6F1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of POU6F1

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr4_+_28437071 0.29 ENST00000509416.1
RP11-123O22.1
RP11-123O22.1
chr20_+_5987890 0.28 ENST00000378868.4
CRLS1
cardiolipin synthase 1
chr5_+_115177178 0.28 ENST00000316788.7
AP3S1
adaptor-related protein complex 3, sigma 1 subunit
chr12_+_102513950 0.28 ENST00000378128.3
ENST00000327680.2
ENST00000541394.1
ENST00000543784.1
PARPBP
PARP1 binding protein
chr7_-_77427676 0.25 ENST00000257663.3
TMEM60
transmembrane protein 60
chr1_-_197115818 0.25 ENST00000367409.4
ENST00000294732.7
ASPM
asp (abnormal spindle) homolog, microcephaly associated (Drosophila)
chr13_+_107028897 0.25 ENST00000439790.1
ENST00000435024.1
LINC00460
long intergenic non-protein coding RNA 460
chr4_+_78829479 0.24 ENST00000504901.1
MRPL1
mitochondrial ribosomal protein L1
chr12_+_102514019 0.23 ENST00000537257.1
ENST00000358383.5
ENST00000392911.2
PARPBP
PARP1 binding protein
chr5_+_162864575 0.22 ENST00000512163.1
ENST00000393929.1
ENST00000340828.2
ENST00000511683.2
ENST00000510097.1
ENST00000511490.2
ENST00000510664.1
CCNG1
cyclin G1
chr11_-_93583697 0.19 ENST00000409977.1
VSTM5
V-set and transmembrane domain containing 5
chr19_+_52076425 0.19 ENST00000436511.2
ZNF175
zinc finger protein 175
chr4_-_169401628 0.17 ENST00000514748.1
ENST00000512371.1
ENST00000260184.7
ENST00000505890.1
ENST00000511577.1
DDX60L
DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like
chr2_+_207220463 0.17 ENST00000598562.1
AC017081.1
Uncharacterized protein
chr6_-_111804905 0.16 ENST00000358835.3
ENST00000435970.1
REV3L
REV3-like, polymerase (DNA directed), zeta, catalytic subunit
chrX_+_119737806 0.14 ENST00000371317.5
MCTS1
malignant T cell amplified sequence 1
chr22_+_31518938 0.14 ENST00000412985.1
ENST00000331075.5
ENST00000412277.2
ENST00000420017.1
ENST00000400294.2
ENST00000405300.1
ENST00000404390.3
INPP5J
inositol polyphosphate-5-phosphatase J
chr9_-_13165457 0.14 ENST00000542239.1
ENST00000538841.1
ENST00000433359.2
MPDZ
multiple PDZ domain protein
chr6_-_110501126 0.13 ENST00000368938.1
WASF1
WAS protein family, member 1
chr19_+_10959043 0.13 ENST00000397820.4
C19orf38
chromosome 19 open reading frame 38
chrX_+_102024075 0.13 ENST00000431616.1
ENST00000440496.1
ENST00000420471.1
ENST00000435966.1
LINC00630
long intergenic non-protein coding RNA 630
chr19_+_42817527 0.13 ENST00000598766.1
TMEM145
transmembrane protein 145
chr15_-_85259294 0.12 ENST00000558217.1
ENST00000558196.1
ENST00000558134.1
SEC11A
SEC11 homolog A (S. cerevisiae)
chr13_+_98612446 0.12 ENST00000496368.1
ENST00000421861.2
ENST00000357602.3
IPO5
importin 5
chr20_+_58515417 0.12 ENST00000360816.3
FAM217B
family with sequence similarity 217, member B
chr17_-_39677971 0.12 ENST00000393976.2
KRT15
keratin 15
chr1_+_225117350 0.12 ENST00000413949.2
ENST00000430092.1
ENST00000366850.3
ENST00000400952.3
ENST00000366849.1
DNAH14
dynein, axonemal, heavy chain 14
chr14_+_39944025 0.11 ENST00000554328.1
ENST00000556620.1
ENST00000557197.1
RP11-111A21.1
RP11-111A21.1
chr15_+_80351977 0.11 ENST00000559157.1
ENST00000561012.1
ENST00000564367.1
ENST00000558494.1
ZFAND6
zinc finger, AN1-type domain 6
chr4_-_83812157 0.11 ENST00000513323.1
SEC31A
SEC31 homolog A (S. cerevisiae)
chr18_+_52495426 0.11 ENST00000262094.5
RAB27B
RAB27B, member RAS oncogene family
chr15_-_85259384 0.10 ENST00000455959.3
SEC11A
SEC11 homolog A (S. cerevisiae)
chr11_+_85339623 0.10 ENST00000358867.6
ENST00000534341.1
ENST00000393375.1
ENST00000531274.1
TMEM126B
transmembrane protein 126B
chr8_+_92261516 0.10 ENST00000276609.3
ENST00000309536.2
SLC26A7
solute carrier family 26 (anion exchanger), member 7
chr5_+_67586465 0.10 ENST00000336483.5
PIK3R1
phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
chr12_-_57443886 0.09 ENST00000300119.3
MYO1A
myosin IA
chr15_+_45028719 0.09 ENST00000560442.1
ENST00000558329.1
ENST00000561043.1
TRIM69
tripartite motif containing 69
chr6_-_47010061 0.09 ENST00000371253.2
GPR110
G protein-coupled receptor 110
chr21_-_34915123 0.09 ENST00000438059.1
GART
phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase
chr6_-_111136299 0.08 ENST00000457688.1
CDK19
cyclin-dependent kinase 19
chr2_+_102721023 0.08 ENST00000409589.1
ENST00000409329.1
IL1R1
interleukin 1 receptor, type I
chr15_-_85259330 0.08 ENST00000560266.1
SEC11A
SEC11 homolog A (S. cerevisiae)
chr6_+_110501621 0.08 ENST00000368930.1
ENST00000307731.1
CDC40
cell division cycle 40
chr1_-_222014008 0.07 ENST00000431729.1
RP11-191N8.2
RP11-191N8.2
chr14_-_70883708 0.07 ENST00000256366.4
SYNJ2BP
synaptojanin 2 binding protein
chr1_-_153538292 0.07 ENST00000497140.1
ENST00000368708.3
S100A2
S100 calcium binding protein A2
chr1_+_176432298 0.07 ENST00000367661.3
ENST00000367662.3
PAPPA2
pappalysin 2
chr13_-_52027134 0.06 ENST00000311234.4
ENST00000425000.1
ENST00000463928.1
ENST00000442263.3
ENST00000398119.2
INTS6
integrator complex subunit 6
chr15_-_31283618 0.06 ENST00000563714.1
MTMR10
myotubularin related protein 10
chr11_+_12302492 0.06 ENST00000533534.1
MICALCL
MICAL C-terminal like
chr4_+_106631966 0.06 ENST00000360505.5
ENST00000510865.1
ENST00000509336.1
GSTCD
glutathione S-transferase, C-terminal domain containing
chr2_-_85828867 0.06 ENST00000425160.1
TMEM150A
transmembrane protein 150A
chr13_+_49551020 0.06 ENST00000541916.1
FNDC3A
fibronectin type III domain containing 3A
chr6_+_110501344 0.06 ENST00000368932.1
CDC40
cell division cycle 40
chr17_-_30186328 0.06 ENST00000302362.6
COPRS
coordinator of PRMT5, differentiation stimulator
chr16_-_58718638 0.06 ENST00000562397.1
ENST00000564010.1
ENST00000570214.1
ENST00000563196.1
SLC38A7
solute carrier family 38, member 7
chr2_+_242289502 0.06 ENST00000451310.1
SEPT2
septin 2
chr13_+_107029084 0.06 ENST00000444865.1
LINC00460
long intergenic non-protein coding RNA 460
chr18_+_9475001 0.05 ENST00000019317.4
RALBP1
ralA binding protein 1
chr3_-_108248169 0.05 ENST00000273353.3
MYH15
myosin, heavy chain 15
chr22_-_32767017 0.05 ENST00000400234.1
RFPL3S
RFPL3 antisense
chr10_+_18041218 0.04 ENST00000480516.1
ENST00000457860.1
TMEM236
TMEM236
chr6_-_111136513 0.04 ENST00000368911.3
CDK19
cyclin-dependent kinase 19
chr15_+_80351910 0.04 ENST00000261749.6
ENST00000561060.1
ZFAND6
zinc finger, AN1-type domain 6
chr4_+_123161120 0.04 ENST00000446180.1
KIAA1109
KIAA1109
chr10_-_94257512 0.04 ENST00000371581.5
IDE
insulin-degrading enzyme
chr19_+_45116921 0.04 ENST00000402988.1
IGSF23
immunoglobulin superfamily, member 23
chrX_-_122756660 0.03 ENST00000441692.1
THOC2
THO complex 2
chr9_-_89562104 0.03 ENST00000298743.7
GAS1
growth arrest-specific 1
chr17_-_25568687 0.03 ENST00000581944.1
RP11-663N22.1
RP11-663N22.1
chr9_+_12685439 0.03 ENST00000473763.1
TYRP1
tyrosinase-related protein 1
chr2_+_191045562 0.03 ENST00000340623.4
C2orf88
chromosome 2 open reading frame 88
chr6_-_47009996 0.03 ENST00000371243.2
GPR110
G protein-coupled receptor 110
chr11_+_118398178 0.02 ENST00000302783.4
ENST00000539546.1
TTC36
tetratricopeptide repeat domain 36
chr12_+_49297887 0.02 ENST00000266984.5
CCDC65
coiled-coil domain containing 65
chr20_+_58203664 0.02 ENST00000541461.1
PHACTR3
phosphatase and actin regulator 3
chr16_+_15744078 0.02 ENST00000396354.1
ENST00000570727.1
NDE1
nudE neurodevelopment protein 1
chr12_+_54892550 0.01 ENST00000545638.2
NCKAP1L
NCK-associated protein 1-like
chr8_-_146176199 0.01 ENST00000532351.1
ENST00000276816.4
ENST00000394909.2
ZNF16
zinc finger protein 16
chr11_+_49050504 0.01 ENST00000332682.7
TRIM49B
tripartite motif containing 49B
chr4_-_76912070 0.01 ENST00000395711.4
ENST00000356260.5
SDAD1
SDA1 domain containing 1
chr6_+_42123141 0.01 ENST00000418175.1
ENST00000541991.1
ENST00000053469.4
ENST00000394237.1
ENST00000372963.1
GUCA1A
RP1-139D8.6
guanylate cyclase activator 1A (retina)
RP1-139D8.6
chr4_-_130692631 0.01 ENST00000500092.2
ENST00000509105.1
RP11-519M16.1
RP11-519M16.1
chr11_-_65149422 0.01 ENST00000526432.1
ENST00000527174.1
SLC25A45
solute carrier family 25, member 45
chr15_-_85259360 0.01 ENST00000559729.1
SEC11A
SEC11 homolog A (S. cerevisiae)
chr1_+_225140372 0.01 ENST00000366848.1
ENST00000439375.2
DNAH14
dynein, axonemal, heavy chain 14
chr7_-_30008849 0.01 ENST00000409497.1
SCRN1
secernin 1
chr12_+_49297899 0.01 ENST00000552942.1
ENST00000320516.4
CCDC65
coiled-coil domain containing 65
chr3_-_127541194 0.01 ENST00000453507.2
MGLL
monoglyceride lipase
chr1_-_151431647 0.01 ENST00000368863.2
ENST00000409503.1
ENST00000491586.1
ENST00000533351.1
ENST00000540984.1
POGZ
pogo transposable element with ZNF domain
chr7_+_48494660 0.00 ENST00000411975.1
ENST00000544596.1
ABCA13
ATP-binding cassette, sub-family A (ABC1), member 13
chr2_+_128403439 0.00 ENST00000544369.1
GPR17
G protein-coupled receptor 17
chr11_-_107729887 0.00 ENST00000525815.1
SLC35F2
solute carrier family 35, member F2
chrX_+_43515467 0.00 ENST00000338702.3
ENST00000542639.1
MAOA
monoamine oxidase A

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0009786 regulation of asymmetric cell division(GO:0009786)
0.0 0.1 GO:0002188 translation reinitiation(GO:0002188)
0.0 0.5 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.0 0.3 GO:1904386 response to thyroxine(GO:0097068) response to L-phenylalanine derivative(GO:1904386)
0.0 0.2 GO:0031120 snRNA pseudouridine synthesis(GO:0031120)
0.0 0.1 GO:0019236 response to pheromone(GO:0019236)
0.0 0.1 GO:2000661 positive regulation of interleukin-1-mediated signaling pathway(GO:2000661)
0.0 0.3 GO:0006465 signal peptide processing(GO:0006465)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 GO:0005787 signal peptidase complex(GO:0005787)
0.0 0.2 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.0 0.2 GO:0072687 meiotic spindle(GO:0072687)
0.0 0.2 GO:0072588 box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588)
0.0 0.3 GO:0030123 AP-3 adaptor complex(GO:0030123)
0.0 0.1 GO:1990578 perinuclear endoplasmic reticulum membrane(GO:1990578)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0008808 cardiolipin synthase activity(GO:0008808) phosphatidyltransferase activity(GO:0030572) CDP-diacylglycerol-phosphatidylglycerol phosphatidyltransferase activity(GO:0043337)
0.0 0.2 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.0 0.1 GO:0004644 phosphoribosylamine-glycine ligase activity(GO:0004637) phosphoribosylformylglycinamidine cyclo-ligase activity(GO:0004641) phosphoribosylglycinamide formyltransferase activity(GO:0004644)
0.0 0.0 GO:0031626 beta-endorphin binding(GO:0031626)
0.0 0.1 GO:0004445 inositol-polyphosphate 5-phosphatase activity(GO:0004445)
0.0 0.1 GO:0004909 interleukin-1, Type I, activating receptor activity(GO:0004909)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0 0.3 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG