Results for YPL230W
Z-value: 2.04
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| YMR175W Show fit | 55.15 |
Protein of unknown function whose expression is induced by osmotic stress |
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| YMR107W Show fit | 36.48 |
Protein required for survival at high temperature during stationary phase; not required for growth on nonfermentable carbon sources |
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| YHR139C Show fit | 32.33 |
Protein required for spore wall maturation; expressed during sporulation; may be a component of the spore wall |
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| YKL217W Show fit | 32.32 |
Lactate transporter, required for uptake of lactate and pyruvate; phosphorylated; expression is derepressed by transcriptional activator Cat8p during respiratory growth, and repressed in the presence of glucose, fructose, and mannose |
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| YGR087C Show fit | 32.17 |
Minor isoform of pyruvate decarboxylase, decarboxylates pyruvate to acetaldehyde, involved in amino acid catabolism; transcription is glucose- and ethanol-dependent, and is strongly induced during sulfur limitation |
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| YOL052C-A Show fit | 30.88 |
Multistress response protein, expression is activated by a variety of xenobiotic agents and environmental or physiological stresses |
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| YNR034W-A Show fit | 28.73 |
Putative protein of unknown function; expression is regulated by Msn2p/Msn4p |
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| YNL117W Show fit | 26.46 |
Malate synthase, enzyme of the glyoxylate cycle, involved in utilization of non-fermentable carbon sources; expression is subject to carbon catabolite repression; localizes in peroxisomes during growth in oleic acid medium |
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| YEL039C Show fit | 26.01 |
Cytochrome c isoform 2, expressed under hypoxic conditions; electron carrier of the mitochondrial intermembrane space that transfers electrons from ubiquinone-cytochrome c oxidoreductase to cytochrome c oxidase during cellular respiration |
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| YPL223C Show fit | 25.65 |
Hydrophilin of unknown function; stress induced (osmotic, ionic, oxidative, heat shock and heavy metals); regulated by the HOG pathway |
Network of associatons between targets according to the STRING database.
First level regulatory network of YPL230W
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 6.7 | 60.4 | GO:0006097 | glyoxylate cycle(GO:0006097) |
| 3.4 | 58.0 | GO:0005978 | glycogen biosynthetic process(GO:0005978) |
| 5.7 | 56.6 | GO:0006122 | mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122) |
| 13.4 | 53.7 | GO:0071462 | response to water(GO:0009415) cellular response to water stimulus(GO:0071462) |
| 13.2 | 53.0 | GO:0006848 | pyruvate transport(GO:0006848) |
| 1.1 | 45.2 | GO:0070590 | ascospore wall assembly(GO:0030476) spore wall assembly(GO:0042244) spore wall biogenesis(GO:0070590) ascospore wall biogenesis(GO:0070591) fungal-type cell wall assembly(GO:0071940) |
| 6.2 | 43.7 | GO:0006083 | acetate metabolic process(GO:0006083) |
| 1.8 | 43.4 | GO:0061726 | mitophagy(GO:0000422) mitochondrion disassembly(GO:0061726) |
| 2.7 | 42.6 | GO:0006754 | ATP biosynthetic process(GO:0006754) |
| 0.9 | 40.4 | GO:0009060 | aerobic respiration(GO:0009060) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.4 | 257.2 | GO:0005739 | mitochondrion(GO:0005739) |
| 0.5 | 78.0 | GO:0000322 | storage vacuole(GO:0000322) lytic vacuole(GO:0000323) fungal-type vacuole(GO:0000324) |
| 0.5 | 69.2 | GO:0005743 | mitochondrial inner membrane(GO:0005743) |
| 1.0 | 46.0 | GO:0005758 | mitochondrial intermembrane space(GO:0005758) |
| 3.2 | 41.1 | GO:0070469 | respiratory chain(GO:0070469) |
| 3.4 | 40.4 | GO:0005782 | peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907) |
| 2.2 | 39.3 | GO:0031306 | intrinsic component of mitochondrial outer membrane(GO:0031306) integral component of mitochondrial outer membrane(GO:0031307) |
| 2.5 | 32.0 | GO:0005619 | ascospore wall(GO:0005619) |
| 3.3 | 29.3 | GO:0045275 | mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275) |
| 8.5 | 25.5 | GO:0000015 | phosphopyruvate hydratase complex(GO:0000015) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.1 | 85.4 | GO:0051082 | unfolded protein binding(GO:0051082) |
| 3.1 | 52.7 | GO:0020037 | heme binding(GO:0020037) tetrapyrrole binding(GO:0046906) |
| 10.1 | 50.6 | GO:0015295 | solute:proton symporter activity(GO:0015295) |
| 3.3 | 46.0 | GO:0005353 | fructose transmembrane transporter activity(GO:0005353) mannose transmembrane transporter activity(GO:0015578) |
| 11.4 | 34.1 | GO:0030414 | endopeptidase inhibitor activity(GO:0004866) peptidase inhibitor activity(GO:0030414) |
| 8.0 | 31.9 | GO:0004737 | pyruvate decarboxylase activity(GO:0004737) |
| 10.2 | 30.6 | GO:0003954 | NADH dehydrogenase activity(GO:0003954) NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136) |
| 3.5 | 28.1 | GO:0046912 | transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912) |
| 0.6 | 27.2 | GO:0001077 | transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077) transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228) |
| 4.5 | 26.9 | GO:0016744 | transferase activity, transferring aldehyde or ketonic groups(GO:0016744) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 289.1 | PID P53 DOWNSTREAM PATHWAY | Direct p53 effectors |
| 3.0 | 14.8 | PID ERA GENOMIC PATHWAY | Validated nuclear estrogen receptor alpha network |
| 4.8 | 14.5 | PID IL4 2PATHWAY | IL4-mediated signaling events |
| 3.2 | 9.5 | PID ERBB4 PATHWAY | ErbB4 signaling events |
| 2.5 | 7.5 | PID HNF3B PATHWAY | FOXA2 and FOXA3 transcription factor networks |
| 0.8 | 4.8 | PID MYC ACTIV PATHWAY | Validated targets of C-MYC transcriptional activation |
| 1.9 | 3.8 | PID EPHA2 FWD PATHWAY | EPHA2 forward signaling |
| 1.1 | 3.2 | PID FOXO PATHWAY | FoxO family signaling |
| 0.7 | 2.0 | NABA ECM REGULATORS | Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix |
| 1.7 | 1.7 | PID AR PATHWAY | Coregulation of Androgen receptor activity |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 273.7 | REACTOME CHONDROITIN SULFATE BIOSYNTHESIS | Genes involved in Chondroitin sulfate biosynthesis |
| 3.8 | 42.0 | REACTOME GLUCOSE METABOLISM | Genes involved in Glucose metabolism |
| 6.8 | 20.3 | REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S | Genes involved in Activation of Chaperone Genes by XBP1(S) |
| 4.7 | 9.5 | REACTOME SHC1 EVENTS IN ERBB4 SIGNALING | Genes involved in SHC1 events in ERBB4 signaling |
| 3.0 | 9.0 | REACTOME MEIOTIC SYNAPSIS | Genes involved in Meiotic Synapsis |
| 1.8 | 3.7 | REACTOME PYRUVATE METABOLISM AND CITRIC ACID TCA CYCLE | Genes involved in Pyruvate metabolism and Citric Acid (TCA) cycle |
| 0.4 | 3.6 | REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES | Genes involved in Metabolism of amino acids and derivatives |
| 0.4 | 1.6 | REACTOME DOUBLE STRAND BREAK REPAIR | Genes involved in Double-Strand Break Repair |
| 0.3 | 1.3 | REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS | Genes involved in Apoptotic cleavage of cellular proteins |
| 0.2 | 1.3 | REACTOME MEIOTIC RECOMBINATION | Genes involved in Meiotic Recombination |