Results for YOX1
Z-value: 1.05
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Transcription factors associated with YOX1
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
|
YOX1
|
S000004489 | Homeobox transcriptional repressor |
Activity-expression correlation:
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| YJR094W-A Show fit | 6.71 |
Protein component of the large (60S) ribosomal subunit, identical to Rpl43Ap and has similarity to rat L37a ribosomal protein |
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| YOL086C Show fit | 6.52 |
Alcohol dehydrogenase, fermentative isozyme active as homo- or heterotetramers; required for the reduction of acetaldehyde to ethanol, the last step in the glycolytic pathway |
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| YFR056C Show fit | 6.17 |
Dubious open reading frame unlikely to encode a protein based on available experimental and comparative sequence data; partially overlaps the uncharacterized gene YFR055W |
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| YFR055W Show fit | 5.86 |
Putative cystathionine beta-lyase; involved in copper ion homeostasis and sulfur metabolism; null mutant displays increased levels of spontaneous Rad52p foci; expression induced by nitrogen limitation in a GLN3, GAT1-dependent manner |
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| YHR180W-A Show fit | 4.57 |
Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps dubious ORF YHR180C-B and long terminal repeat YHRCsigma3 |
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| YPR119W Show fit | 3.79 |
B-type cyclin involved in cell cycle progression; activates Cdc28p to promote the transition from G2 to M phase; accumulates during G2 and M, then targeted via a destruction box motif for ubiquitin-mediated degradation by the proteasome |
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| YNR001W-A Show fit | 3.62 |
Dubious open reading frame unlikely to encode a functional protein; identified by homology |
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| YHR181W Show fit | 3.27 |
Integral membrane protein of the early Golgi apparatus and endoplasmic reticulum, involved in COP II vesicle transport; may also function to promote retention of proteins in the early Golgi compartment |
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| YDR471W Show fit | 3.03 |
Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl27Ap and has similarity to rat L27 ribosomal protein |
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| YLR333C Show fit | 3.00 |
Protein component of the small (40S) ribosomal subunit; nearly identical to Rps25Ap and has similarity to rat S25 ribosomal protein |
Network of associatons between targets according to the STRING database.
First level regulatory network of YOX1
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 44.4 | GO:0002181 | cytoplasmic translation(GO:0002181) |
| 0.9 | 6.3 | GO:0019655 | glucose catabolic process(GO:0006007) glycolytic fermentation to ethanol(GO:0019655) glycolytic fermentation(GO:0019660) hexose catabolic process to ethanol(GO:1902707) |
| 0.9 | 6.2 | GO:0010696 | positive regulation of spindle pole body separation(GO:0010696) |
| 1.7 | 5.0 | GO:0000098 | sulfur amino acid catabolic process(GO:0000098) |
| 0.7 | 4.7 | GO:0043137 | DNA replication, removal of RNA primer(GO:0043137) |
| 0.3 | 3.3 | GO:0045053 | protein retention in Golgi apparatus(GO:0045053) |
| 0.1 | 3.3 | GO:0051445 | regulation of meiotic nuclear division(GO:0040020) regulation of meiotic cell cycle(GO:0051445) |
| 0.7 | 3.0 | GO:0014070 | response to organic cyclic compound(GO:0014070) response to cycloheximide(GO:0046898) |
| 0.5 | 2.7 | GO:0001676 | long-chain fatty acid metabolic process(GO:0001676) |
| 0.2 | 2.7 | GO:0032508 | DNA duplex unwinding(GO:0032508) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.4 | 31.9 | GO:0022625 | cytosolic large ribosomal subunit(GO:0022625) |
| 0.3 | 17.5 | GO:0022627 | cytosolic small ribosomal subunit(GO:0022627) |
| 0.1 | 4.6 | GO:0005816 | microtubule organizing center(GO:0005815) spindle pole body(GO:0005816) |
| 1.5 | 4.5 | GO:0032299 | ribonuclease H2 complex(GO:0032299) |
| 0.2 | 3.7 | GO:0000307 | cyclin-dependent protein kinase holoenzyme complex(GO:0000307) |
| 0.0 | 3.6 | GO:0005933 | cellular bud(GO:0005933) |
| 0.1 | 3.3 | GO:0031228 | integral component of Golgi membrane(GO:0030173) intrinsic component of Golgi membrane(GO:0031228) |
| 0.2 | 2.5 | GO:0005736 | DNA-directed RNA polymerase I complex(GO:0005736) |
| 0.1 | 2.2 | GO:0032541 | cortical endoplasmic reticulum(GO:0032541) |
| 0.1 | 2.0 | GO:0005811 | lipid particle(GO:0005811) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 48.1 | GO:0003735 | structural constituent of ribosome(GO:0003735) |
| 0.3 | 6.6 | GO:0019901 | protein kinase binding(GO:0019901) |
| 1.1 | 6.5 | GO:0004022 | alcohol dehydrogenase (NAD) activity(GO:0004022) |
| 1.0 | 5.9 | GO:0016846 | carbon-sulfur lyase activity(GO:0016846) |
| 1.1 | 4.5 | GO:0004523 | RNA-DNA hybrid ribonuclease activity(GO:0004523) |
| 0.1 | 3.6 | GO:0030674 | protein binding, bridging(GO:0030674) |
| 0.1 | 3.5 | GO:0008092 | cytoskeletal protein binding(GO:0008092) |
| 0.6 | 2.5 | GO:0004467 | long-chain fatty acid-CoA ligase activity(GO:0004467) |
| 0.2 | 2.5 | GO:0001054 | RNA polymerase I activity(GO:0001054) |
| 0.8 | 2.3 | GO:0015166 | polyol transmembrane transporter activity(GO:0015166) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 0.8 | PID ATR PATHWAY | ATR signaling pathway |
| 0.2 | 0.7 | PID P38 ALPHA BETA DOWNSTREAM PATHWAY | Signaling mediated by p38-alpha and p38-beta |
| 0.2 | 0.5 | PID INTEGRIN A4B1 PATHWAY | Alpha4 beta1 integrin signaling events |
| 0.1 | 0.3 | PID HIF1 TFPATHWAY | HIF-1-alpha transcription factor network |
| 0.1 | 0.3 | PID E2F PATHWAY | E2F transcription factor network |
| 0.0 | 0.2 | NABA SECRETED FACTORS | Genes encoding secreted soluble factors |
| 0.0 | 0.1 | PID TRKR PATHWAY | Neurotrophic factor-mediated Trk receptor signaling |
| 0.0 | 0.0 | PID MYC PATHWAY | C-MYC pathway |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.6 | 5.1 | REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX | Genes involved in Formation of the ternary complex, and subsequently, the 43S complex |
| 0.2 | 2.7 | REACTOME PEPTIDE CHAIN ELONGATION | Genes involved in Peptide chain elongation |
| 0.2 | 1.7 | REACTOME UNWINDING OF DNA | Genes involved in Unwinding of DNA |
| 0.2 | 0.8 | REACTOME GLYCOLYSIS | Genes involved in Glycolysis |
| 0.2 | 0.6 | REACTOME SIGNALING BY RHO GTPASES | Genes involved in Signaling by Rho GTPases |
| 0.1 | 0.6 | REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE | Genes involved in SRP-dependent cotranslational protein targeting to membrane |
| 0.1 | 0.4 | REACTOME PROTEIN FOLDING | Genes involved in Protein folding |
| 0.0 | 0.4 | REACTOME M G1 TRANSITION | Genes involved in M/G1 Transition |
| 0.1 | 0.3 | REACTOME MRNA 3 END PROCESSING | Genes involved in mRNA 3'-end processing |
| 0.1 | 0.2 | REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS | Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements |