Results for YGR067C

Z-value: 0.87

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Transcription factors associated with YGR067C

Gene Symbol Gene ID Gene Info
S000003299 Putative protein of unknown function

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot

Activity profile of YGR067C motif

Sorted Z-values of YGR067C motif

Promoter Log-likelihood Transcript Gene Gene Info
YGR067C 11.66 Putative protein of unknown function; contains a zinc finger motif similar to that of Adr1p
YOR348C 9.72 Proline permease, required for high-affinity transport of proline; also transports the toxic proline analog azetidine-2-carboxylate (AzC); PUT4 transcription is repressed in ammonia-grown cells
YOR100C 9.27 Mitochondrial inner membrane carnitine transporter, required for carnitine-dependent transport of acetyl-CoA from peroxisomes to mitochondria during fatty acid beta-oxidation
YDR536W 6.45 Glycerol proton symporter of the plasma membrane, subject to glucose-induced inactivation, strongly but transiently induced when cells are subjected to osmotic shock
YHR217C 5.82 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; located in the telomeric region TEL08R.
YDR342C 5.77 High-affinity glucose transporter of the major facilitator superfamily, nearly identical to Hxt6p, expressed at high basal levels relative to other HXTs, expression repressed by high glucose levels
YLR312C 5.73 Protein of unknown function; null mutant quiescent and non-quiescent cells exhibit reduced reproductive capacity
YKL163W 5.24 O-glycosylated covalently-bound cell wall protein required for cell wall stability; expression is cell cycle regulated, peaking in M/G1 and also subject to regulation by the cell integrity pathway
YMR107W 5.12 Protein required for survival at high temperature during stationary phase; not required for growth on nonfermentable carbon sources
YFL052W 4.99 Putative zinc cluster protein that contains a DNA binding domain; null mutant sensitive to calcofluor white, low osmolarity and heat, suggesting a role for YFL052Wp in cell wall integrity
YIL057C 4.66 Putative protein of unknown function; expression induced under carbon limitation and repressed under high glucose
YDR096W 4.64 JmjC domain-containing histone demethylase; transcription factor involved in the expression of genes during nutrient limitation; also involved in the negative regulation of DPP1 and PHR1
YAR053W 4.61 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data
YPL230W 4.38 Putative transcription factor containing a C2H2 zinc finger; mutation affects transcriptional regulation of genes involved in protein folding, ATP binding, and cell wall biosynthesis
YFR053C 4.38 Hexokinase isoenzyme 1, a cytosolic protein that catalyzes phosphorylation of glucose during glucose metabolism; expression is highest during growth on non-glucose carbon sources; glucose-induced repression involves the hexokinase Hxk2p
YOL052C-A 4.26 Multistress response protein, expression is activated by a variety of xenobiotic agents and environmental or physiological stresses
YDR277C 4.23 Negative regulator of the glucose-sensing signal transduction pathway, required for repression of transcription by Rgt1p; interacts with Rgt1p and the Snf3p and Rgt2p glucose sensors; phosphorylated by Yck1p, triggering Mth1p degradation
YNR073C 4.16 Putative mannitol dehydrogenase
YGR243W 4.04 Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies
YOR178C 3.97 Regulatory subunit for Glc7p type-1 protein phosphatase (PP1), tethers Glc7p to Gsy2p glycogen synthase, binds Hsf1p heat shock transcription factor, required for induction of some HSF-regulated genes under heat shock
YML042W 3.94 Carnitine acetyl-CoA transferase present in both mitochondria and peroxisomes, transfers activated acetyl groups to carnitine to form acetylcarnitine which can be shuttled across membranes
YLR023C 3.91 Membrane protein involved in zinc metabolism, member of the four-protein IZH family, expression induced by zinc deficiency; deletion reduces sensitivity to elevated zinc and shortens lag phase, overexpression reduces Zap1p activity
YNL036W 3.86 Carbonic anhydrase; poorly transcribed under aerobic conditions and at an undetectable level under anaerobic conditions; involved in non-classical protein export pathway
YML089C 3.83 Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data; expression induced by calcium shortage
YMR194C-B 3.70 Putative protein of unknown function
YOR383C 3.69 Mannoprotein that is incorporated into the cell wall via a glycosylphosphatidylinositol (GPI) anchor, involved in the retention of siderophore-iron in the cell wall
YFR017C 3.53 Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and is induced in response to the DNA-damaging agent MMS; YFR017C is not an essential gene
YOR382W 3.46 Mannoprotein that is incorporated into the cell wall via a glycosylphosphatidylinositol (GPI) anchor, involved in the retention of siderophore-iron in the cell wall
YFL011W 3.42 Putative hexose transporter, expressed at low levels and expression is repressed by glucose
YKL031W 3.30 Dubious open reading frame, unlikely to encode a protein; not conserved in closely related Saccharomyces species
YHR218W 3.24 Helicase-like protein encoded within the telomeric Y' element
YHR211W 3.16 Lectin-like cell wall protein (flocculin) involved in flocculation, binds to mannose chains on the surface of other cells, confers floc-forming ability that is chymotrypsin resistant but heat labile; similar to Flo1p
YAR060C 3.15 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data
YMR191W 3.14 Protein required for survival at high temperature during stationary phase; not required for growth on nonfermentable carbon sources
YKL026C 3.11 Phospholipid hydroperoxide glutathione peroxidase induced by glucose starvation that protects cells from phospholipid hydroperoxides and nonphospholipid peroxides during oxidative stress
YKL217W 3.06 Lactate transporter, required for uptake of lactate and pyruvate; phosphorylated; expression is derepressed by transcriptional activator Cat8p during respiratory growth, and repressed in the presence of glucose, fructose, and mannose
YPL061W 3.03 Cytosolic aldehyde dehydrogenase, activated by Mg2+ and utilizes NADP+ as the preferred coenzyme; required for conversion of acetaldehyde to acetate; constitutively expressed; locates to the mitochondrial outer surface upon oxidative stress
YJR146W 3.02 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified gene HMS2
YDR119W-A 2.98 Putative protein of unknown function
YKL109W 2.96 Subunit of the heme-activated, glucose-repressed Hap2p/3p/4p/5p CCAAT-binding complex, a transcriptional activator and global regulator of respiratory gene expression; provides the principal activation function of the complex
YPL119C 2.83 Putative ATP-dependent RNA helicase of the DEAD-box protein family; mutants show reduced stability of the 40S ribosomal subunit scanning through 5' untranslated regions of mRNAs
YEL039C 2.83 Cytochrome c isoform 2, expressed under hypoxic conditions; electron carrier of the mitochondrial intermembrane space that transfers electrons from ubiquinone-cytochrome c oxidoreductase to cytochrome c oxidase during cellular respiration
YHR212W-A 2.83 Putative protein of unknown function; identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching
YHR212C 2.72 Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data
YGR023W 2.63 Protein with both structural and functional similarity to Mid2p, which is a plasma membrane sensor required for cell integrity signaling during pheromone-induced morphogenesis; suppresses rgd1 null mutations
YJR115W 2.62 Putative protein of unknown function
YBR051W 2.60 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partiallly overlaps the REG2/YBR050C regulatory subunit of the Glc7p type-1 protein phosphatase
YML090W 2.56 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the dubious ORF YML089C; exhibits growth defect on a non-fermentable (respiratory) carbon source
YPR030W 2.54 Nuclear protein with a potential regulatory role in utilization of galactose and nonfermentable carbon sources; overproduction suppresses the lethality at high temperature of a chs5 spa2 double null mutation; potential Cdc28p substrate
YGR022C 2.52 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; overlaps almost completely with the verified ORF MTL1/YGR023W
YMR195W 2.50 Protein of unknown function, required for viability in rich media of cells lacking mitochondrial DNA; mutants have an invasive growth defect with elongated morphology; induced by amino acid starvation
YFL063W 2.49 Dubious open reading frame, based on available experimental and comparative sequence data
YEL070W 2.48 Deletion suppressor of mpt5 mutation
YLR004C 2.47 Putative plasma membrane permease proposed to be involved in carboxylic acid uptake and repressed by thiamine; substrate of Dbf2p/Mob1p kinase; transcription is altered if mitochondrial dysfunction occurs
YMR081C 2.44 Serine-rich, hydrophilic protein with similarity to Mbr1p; overexpression suppresses growth defects of hap2, hap3, and hap4 mutants; expression is under glucose control; cotranscribed with NAM7 in a cyp1 mutant
YGL146C 2.41 Putative protein of unknown function, contains two putative transmembrane spans, shows no significant homology to any other known protein sequence, YGL146C is not an essential gene
YBR050C 2.35 Regulatory subunit of the Glc7p type-1 protein phosphatase; involved with Reg1p, Glc7p, and Snf1p in regulation of glucose-repressible genes, also involved in glucose-induced proteolysis of maltose permease
YJL045W 2.33 Minor succinate dehydrogenase isozyme; homologous to Sdh1p, the major isozyme reponsible for the oxidation of succinate and transfer of electrons to ubiquinone; induced during the diauxic shift in a Cat8p-dependent manner
YBR105C 2.29 Peripheral membrane protein located at Vid (vacuole import and degradation) vesicles; regulates fructose-1,6-bisphosphatase (FBPase) targeting to the vacuole; involved in proteasome-dependent catabolite degradation of FBPase
YLR327C 2.26 Protein of unknown function that associates with ribosomes
YML091C 2.25 Protein subunit of mitochondrial RNase P, has roles in nuclear transcription, cytoplasmic and mitochondrial RNA processing, and mitochondrial translation; distributed to mitochondria, cytoplasmic processing bodies, and the nucleus
YOR235W 2.24 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; null mutant displays increased levels of spontaneous Rad52 foci
YPR006C 2.20 2-methylisocitrate lyase of the mitochondrial matrix, functions in the methylcitrate cycle to catalyze the conversion of 2-methylisocitrate to succinate and pyruvate; ICL2 transcription is repressed by glucose and induced by ethanol
YOL051W 2.16 Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; affects transcription by acting as target of activators and repressors
YGR183C 2.12 Subunit 9 of the ubiquinol cytochrome-c reductase complex, which is a component of the mitochondrial inner membrane electron transport chain; required for electron transfer at the ubiquinol oxidase site of the complex
YIL055C 2.11 Putative protein of unknown function
YEL011W 2.06 Glycogen branching enzyme, involved in glycogen accumulation; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern
YLR377C 2.06 Fructose-1,6-bisphosphatase, key regulatory enzyme in the gluconeogenesis pathway, required for glucose metabolism
YNL305C 2.06 Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the vacuole; YNL305C is not an essential gene
YFL064C 2.04 Putative protein of unknown function
YOR343C 2.02 Dubious open reading frame, unlikely to encode a functional protein; based on available experimental and comparative sequence data
YDR343C 2.01 High-affinity glucose transporter of the major facilitator superfamily, nearly identical to Hxt7p, expressed at high basal levels relative to other HXTs, repression of expression by high glucose requires SNF3
YDL079C 2.00 Glycogen synthase kinase 3 (GSK-3) homolog; one of four GSK-3 homologs in S. cerevisiae that function to activate Msn2p-dependent transcription of stress responsive genes and that function in protein degradation
YPR184W 1.96 Glycogen debranching enzyme containing glucanotranferase and alpha-1,6-amyloglucosidase activities, required for glycogen degradation; phosphorylated in mitochondria
YPR026W 1.96 Acid trehalase required for utilization of extracellular trehalose
YOL084W 1.94 Protein of unknown function, expression is regulated by phosphate levels; green fluorescent protein (GFP)-fusion protein localizes to the cell periphery and vacuole
YHR033W 1.93 Putative protein of unknown function; epitope-tagged protein localizes to the cytoplasm
YDL114W 1.92 Putative protein of unknown function with similarity to acyl-carrier-protein reductases; YDL114W is not an essential gene
YJR151C 1.89 Cell wall mannoprotein with similarity to Tir1p, Tir2p, Tir3p, and Tir4p; expressed under anaerobic conditions, completely repressed during aerobic growth
YIL155C 1.89 Mitochondrial glycerol-3-phosphate dehydrogenase; expression is repressed by both glucose and cAMP and derepressed by non-fermentable carbon sources in a Snf1p, Rsf1p, Hap2/3/4/5 complex dependent manner
YMR280C 1.87 Zinc cluster transcriptional activator necessary for derepression of a variety of genes under non-fermentative growth conditions, active after diauxic shift, binds carbon source responsive elements
YKR097W 1.83 Phosphoenolpyruvate carboxykinase, key enzyme in gluconeogenesis, catalyzes early reaction in carbohydrate biosynthesis, glucose represses transcription and accelerates mRNA degradation, regulated by Mcm1p and Cat8p, located in the cytosol
YNL037C 1.83 Subunit of mitochondrial NAD(+)-dependent isocitrate dehydrogenase, which catalyzes the oxidation of isocitrate to alpha-ketoglutarate in the TCA cycle
YDL130W-A 1.83 Protein involved in regulation of the mitochondrial F1F0-ATP synthase; Stf1p and Stf2p may act as stabilizing factors that enhance inhibitory action of the Inh1p protein
YCR068W 1.79 Lipase, required for intravacuolar lysis of autophagosomes; located in the endoplasmic reticulum membrane and targeted to intravacuolar vesicles during autophagy via the multivesicular body (MVB) pathway
YIL107C 1.78 6-phosphofructo-2-kinase, inhibited by phosphoenolpyruvate and sn-glycerol 3-phosphate, has negligible fructose-2,6-bisphosphatase activity, transcriptional regulation involves protein kinase A
YDR406W 1.77 Plasma membrane ATP binding cassette (ABC) transporter, multidrug transporter and general stress response factor implicated in cellular detoxification; regulated by Pdr1p, Pdr3p and Pdr8p; promoter contains a PDR responsive element
YEL012W 1.70 Ubiquitin-conjugating enzyme that negatively regulates gluconeogenesis by mediating the glucose-induced ubiquitination of fructose-1,6-bisphosphatase (FBPase); cytoplasmic enzyme that catalyzes the ubiquitination of histones in vitro
YOR376W 1.69 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; YOR376W is not an essential gene.
YPR150W 1.68 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified gene SUE1/YPR151C
YLR332W 1.67 O-glycosylated plasma membrane protein that acts as a sensor for cell wall integrity signaling and activates the pathway; interacts with Rom2p, a guanine nucleotide exchange factor for Rho1p, and with cell integrity pathway protein Zeo1p
YER187W 1.67 Putative protein of unknown function; induced in respiratory-deficient cells
YMR105C 1.60 Phosphoglucomutase, catalyzes the conversion from glucose-1-phosphate to glucose-6-phosphate, which is a key step in hexose metabolism; functions as the acceptor for a Glc-phosphotransferase
YLR331C 1.59 Dubious open reading frame, unlikely to encode a protein; not conserved in closely related Saccharomyces species; 98% of ORF overlaps the verified gene MID2
YLR267W 1.59 Protein of unknown function, overproduction suppresses a pam1 slv3 double null mutation
YAL061W 1.58 Putative medium-chain alcohol dehydrogenase with similarity to BDH1; transcription induced by constitutively active PDR1 and PDR3; BDH2 is an essential gene
YKL044W 1.58 Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data
YLR111W 1.57 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data
YMR175W 1.57 Protein of unknown function whose expression is induced by osmotic stress
YGL163C 1.56 DNA-dependent ATPase, stimulates strand exchange by modifying the topology of double-stranded DNA; involved in the recombinational repair of double-strand breaks in DNA during vegetative growth and meiosis; member of the SWI/SNF family
YCR007C 1.56 Putative integral membrane protein, member of DUP240 gene family; YCR007C is not an essential gene
YER054C 1.56 Putative regulatory subunit of the protein phosphatase Glc7p, involved in glycogen metabolism; contains a conserved motif (GVNK motif) that is also found in Gac1p, Pig1p, and Pig2p
YNL339C 1.55 Helicase encoded by the Y' element of subtelomeric regions, highly expressed in the mutants lacking the telomerase component TLC1; potentially phosphorylated by Cdc28p
YOR394W 1.52 Hypothetical protein
YPL201C 1.51 Protein that interacts with glycerol 3-phosphatase and plays a role in anaerobic glycerol production; localizes to the nucleus and cytosol
YER188C-A 1.49 Putative protein of unknown function
YLR438W 1.47 L-ornithine transaminase (OTAse), catalyzes the second step of arginine degradation, expression is dually-regulated by allophanate induction and a specific arginine induction process; not nitrogen catabolite repression sensitive
YKL141W 1.42 Cytochrome b subunit of succinate dehydrogenase (Sdh1p, Sdh2p, Sdh3p, Sdh4p), which couples the oxidation of succinate to the transfer of electrons to ubiquinone
YPL282C 1.41 Hypothetical protein
YDR231C 1.40 Mitochondrial inner membrane protein, required for proteolytic processing of Cox2p and its assembly into cytochrome c oxidase
YDR259C 1.39 Putative basic leucine zipper (bZIP) transcription factor; overexpression increases sodium and lithium tolerance
YKL032C 1.38 Protein that binds DNA containing intrastrand cross-links formed by cisplatin, contains two HMG (high mobility group box) domains, which confer the ability to bend cisplatin-modified DNA; mediates aerobic transcriptional repression of COX5b
YIL060W 1.38 Putative protein of unknown function; mutant accumulates less glycogen than does wild type; YIL060W is not an essential gene
YDR010C 1.38 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data
YIL122W 1.37 Putative transcriptional activator that promotes recovery from pheromone induced arrest; inhibits both alpha-factor induced G1 arrest and repression of CLN1 and CLN2 via SCB/MCB promoter elements; potential Cdc28p substrate; SBF regulated
YLL053C 1.37 Putative protein; in the Sigma 1278B strain background YLL053C is contiguous with AQY2 which encodes an aquaporin
YBR021W 1.36 Uracil permease, localized to the plasma membrane; expression is tightly regulated by uracil levels and environmental cues
YOR113W 1.36 Zinc-finger transcription factor, involved in induction of CLN3 transcription in response to glucose; genetic and physical interactions indicate a possible role in mitochondrial transcription or genome maintenance
YLR176C 1.35 Major transcriptional repressor of DNA-damage-regulated genes, recruits repressors Tup1p and Cyc8p to their promoters; involved in DNA damage and replication checkpoint pathway; similar to a family of mammalian DNA binding RFX1-4 proteins
YKR102W 1.34 Lectin-like protein with similarity to Flo1p, thought to be involved in flocculation
YKR096W 1.33 Protein of unknown function that may interact with ribosomes, based on co-purification experiments; green fluorescent protein (GFP)-fusion protein localizes to the nucleus and cytoplasm; predicted to contain a PINc (PilT N terminus) domain
YDR216W 1.33 Carbon source-responsive zinc-finger transcription factor, required for transcription of the glucose-repressed gene ADH2, of peroxisomal protein genes, and of genes required for ethanol, glycerol, and fatty acid utilization
YPR151C 1.33 Mitochondrial protein required for degradation of unstable forms of cytochrome c
YGL117W 1.32 Putative protein of unknown function
YLR122C 1.31 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the dubious ORF YLR123C
YOL047C 1.29 Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern
YLR437C-A 1.25 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified ORF CAR2/YLR438W
YMR272C 1.22 Sphingolipid alpha-hydroxylase, functions in the alpha-hydroxylation of sphingolipid-associated very long chain fatty acids, has both cytochrome b5-like and hydroxylase/desaturase domains, not essential for growth
YLL052C 1.22 Water channel that mediates the transport of water across cell membranes, only expressed in proliferating cells, controlled by osmotic signals, may be involved in freeze tolerance; disrupted by a stop codon in many S. cerevisiae strains
YIL045W 1.22 Putative type-1 protein phosphatase targeting subunit that tethers Glc7p type-1 protein phosphatase to Gsy2p glycogen synthase
YIL112W 1.20 Subunit of the Set3 complex, which is a meiotic-specific repressor of sporulation specific genes that contains deacetylase activity; potential Cdc28p substrate
YMR213W 1.19 Essential splicing factor; associated with Prp19p and the spliceosome, contains an N-terminal c-Myb DNA binding motif necessary for cell viability but not for Prp19p association, evolutionarily conserved and homologous to S. pombe Cdc5p
YBR072W 1.19 Small heat shock protein (sHSP) with chaperone activity; forms hollow, sphere-shaped oligomers that suppress unfolded proteins aggregation; oligomer activation requires a heat-induced conformational change; not expressed in unstressed cells
YJL103C 1.19 Putative zinc cluster protein of unknown function; proposed to be involved in the regulation of energy metabolism, based on patterns of expression and sequence analysis
YPR013C 1.18 Putative zinc finger protein; YPR013C is not an essential gene
YER189W 1.18 Putative protein of unknown function
YOR378W 1.17 Putative protein of unknown function; belongs to the DHA2 family of drug:H+ antiporters; YOR378W is not an essential gene
YLR124W 1.17 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data
YPR015C 1.16 Putative protein of unknown function
YGR236C 1.15 Protein required for survival at high temperature during stationary phase; not required for growth on nonfermentable carbon sources; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies
YNL337W 1.13 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data
YLR123C 1.12 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the dubious ORF YLR122C; contains characteristic aminoacyl-tRNA motif
YHR210C 1.10 Putative protein of unknown function; non-essential gene; highly expressed under anaeorbic conditions; sequence similarity to aldose 1-epimerases such as GAL10
YDL113C 1.10 Sorting nexin family member required for the cytoplasm-to-vacuole targeting (Cvt) pathway and for endosomal sorting; has a Phox homology domain that binds phosphatidylinositol-3-phosphate; interacts with Snx4p; potential Cdc28p substrate
YNL018C 1.10 Putative protein of unknown function
YHR145C 1.09 Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data
YPR010C-A 1.09 Putative protein of unknown function; conserved among Saccharomyces sensu stricto species
YPL057C 1.08 Probable catalytic subunit of a mannosylinositol phosphorylceramide (MIPC) synthase, forms a complex with probable regulatory subunit Csg2p; function in sphingolipid biosynthesis is overlapping with that of Csh1p
YHR205W 1.08 Protein kinase involved in transcriptional activation of osmostress-responsive genes; regulates G1 progression, cAPK activity, nitrogen activation of the FGM pathway; involved in life span regulation; homologous to mammalian Akt/PKB
YCL001W-B 1.07 Putative protein of unknown function; identified by homology
YER142C 1.07 3-methyl-adenine DNA glycosylase involved in protecting DNA against alkylating agents; initiates base excision repair by removing damaged bases to create abasic sites that are subsequently repaired
YER158C 1.04 Protein of unknown function, has similarity to Afr1p; potentially phosphorylated by Cdc28p
YJR160C 1.03 Alpha-glucoside permease, transports maltose, maltotriose, alpha-methylglucoside, and turanose; identical to Mph2p; encoded in a subtelomeric position in a region likely to have undergone duplication
YPR005C 1.02 Cytoplasmic protein involved in halotolerance; decreases intracellular Na+ (via Ena1p) and increases intracellular K+ by decreasing efflux; expression repressed by Ssn6p-Tup1p and Sko1p and induced by NaCl, KCl, and sorbitol through Gcn4p
YBR132C 1.02 High affinity polyamine permease, preferentially uses spermidine over putrescine; expression is down-regulated by osmotic stress; plasma membrane carnitine transporter, also functions as a low-affinity amino acid permease
YKL043W 1.02 Transcriptional activator that enhances pseudohyphal growth; regulates expression of FLO11, an adhesin required for pseudohyphal filament formation; similar to StuA, an A. nidulans developmental regulator; potential Cdc28p substrate
YKL085W 1.01 Mitochondrial malate dehydrogenase, catalyzes interconversion of malate and oxaloacetate; involved in the tricarboxylic acid (TCA) cycle; phosphorylated
YEL044W 0.99 Protein that associates with the INO80 chromatin remodeling complex under low-salt conditions
YJR120W 0.98 Protein of unknown function; essential for growth under anaerobic conditions; mutation causes decreased expression of ATP2, impaired respiration, defective sterol uptake, and altered levels/localization of ABC transporters Aus1p and Pdr11p
YJR159W 0.97 Sorbitol dehydrogenase; expression is induced in the presence of sorbitol
YLR223C 0.97 Essential protein with a highly acidic N-terminal domain; IFH1 exhibits genetic interactions with FHL1, overexpression interferes with silencing at telomeres and HM loci; potential Cdc28p substrate
YOL060C 0.96 Protein required for normal mitochondrial morphology, has similarity to hemolysins
YBR033W 0.95 Putative zinc cluster protein; YBR033W is not an essential gene
YAR035W 0.95 Outer mitochondrial carnitine acetyltransferase, minor ethanol-inducible enzyme involved in transport of activated acyl groups from the cytoplasm into the mitochondrial matrix; phosphorylated
YER111C 0.94 DNA binding component of the SBF complex (Swi4p-Swi6p), a transcriptional activator that in concert with MBF (Mbp1-Swi6p) regulates late G1-specific transcription of targets including cyclins and genes required for DNA synthesis and repair
YMR190C 0.94 Nucleolar DNA helicase of the RecQ family involved in maintenance of genome integrity, regulates chromosome synapsis and meiotic crossing over; has similarity to human BLM and WRN helicases implicated in Bloom and Werner syndromes
YKR095W 0.93 Myosin-like protein associated with the nuclear envelope, connects the nuclear pore complex with the nuclear interior; involved with Tel1p in telomere length control; involved with Pml1p and Pml39p in nuclear retention of unspliced mRNAs
YDR389W 0.93 GTPase activating protein (GAP) for Rho1p, involved in signaling to the actin cytoskeleton, null mutations suppress tor2 mutations and temperature sensitive mutations in actin; potential Cdc28p substrate
YIL136W 0.93 Protein of unknown function, major constituent of the mitochondrial outer membrane; located on the outer (cytosolic) face of the outer membrane
YPR169W-A 0.93 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps two other dubious ORFs: YPR170C and YPR170W-B
YIL125W 0.92 Component of the mitochondrial alpha-ketoglutarate dehydrogenase complex, which catalyzes a key step in the tricarboxylic acid (TCA) cycle, the oxidative decarboxylation of alpha-ketoglutarate to form succinyl-CoA
YOL085W-A 0.91 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the dubious ORF YOL085C
YJL102W 0.90 Mitochondrial elongation factor involved in translational elongation
YBR001C 0.90 Putative neutral trehalase, required for thermotolerance and may mediate resistance to other cellular stresses
YCR010C 0.90 Acetate transporter required for normal sporulation; phosphorylated in mitochondria
YLR334C 0.89 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; overlaps a stand-alone long terminal repeat sequence whose presence indicates a retrotransposition event occurred here
YGR258C 0.88 Single-stranded DNA endonuclease, cleaves single-stranded DNA during nucleotide excision repair to excise damaged DNA; subunit of Nucleotide Excision Repair Factor 3 (NEF3); homolog of human XPG protein
YGL033W 0.88 Meiosis-specific protein that localizes to chromosomes, preventing synapsis between nonhomologous chromosomes and ensuring synapsis between homologs; complexes with Mnd1p to promote homolog pairing and meiotic double-strand break repair
YHR202W 0.88 Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the vacuole, while HA-tagged protein is found in the soluble fraction, suggesting cytoplasmic localization
YBR218C 0.88 Pyruvate carboxylase isoform, cytoplasmic enzyme that converts pyruvate to oxaloacetate; highly similar to isoform Pyc1p but differentially regulated; mutations in the human homolog are associated with lactic acidosis
YPR154W 0.88 Protein that induces appearance of [PIN+] prion when overproduced
YDL244W 0.86 Protein involved in synthesis of the thiamine precursor hydroxymethylpyrimidine (HMP); member of a subtelomeric gene family including THI5, THI11, THI12, and THI13
YER116C 0.86 Subunit of the Slx5-Slx8 substrate-specific ubiquitin ligase complex; stimulated by prior attachment of SUMO to the substrate
YAL062W 0.85 NADP(+)-dependent glutamate dehydrogenase, synthesizes glutamate from ammonia and alpha-ketoglutarate; rate of alpha-ketoglutarate utilization differs from Gdh1p; expression regulated by nitrogen and carbon sources
YFL033C 0.85 Glucose-repressible protein kinase involved in signal transduction during cell proliferation in response to nutrients, specifically the establishment of stationary phase; identified as a regulator of IME2; substrate of Pho80p-Pho85p kinase
YMR135C 0.84 Protein of unknown function, involved in proteasome-dependent catabolite inactivation of fructose-1,6-bisphosphatase; contains LisH and CTLH domains, like Vid30p; dosage-dependent regulator of START
YOR120W 0.83 Putative NADP(+) coupled glycerol dehydrogenase, proposed to be involved in an alternative pathway for glycerol catabolism; member of the aldo-keto reductase (AKR) family
YDR186C 0.83 Putative protein of unknown function; may interact with ribosomes, based on co-purification experiments; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm
YLR174W 0.83 Cytosolic NADP-specific isocitrate dehydrogenase, catalyzes oxidation of isocitrate to alpha-ketoglutarate; levels are elevated during growth on non-fermentable carbon sources and reduced during growth on glucose
YLR149C 0.82 Putative protein of unknown function; YLR149C is not an essential gene
YJL199C 0.81 Dubious open reading frame, unlikely to encode a protein; not conserved in closely related Saccharomyces species; protein detected in large-scale protein-protein interaction studies
YCL025C 0.81 Low-affinity amino acid permease with broad substrate range, involved in uptake of asparagine, glutamine, and other amino acids; expression is regulated by the SPS plasma membrane amino acid sensor system (Ssy1p-Ptr3p-Ssy5p)
YPL250C 0.80 Protein of unknown function; mobilized into polysomes upon a shift from a fermentable to nonfermentable carbon source; potential Cdc28p substrate
YOR023C 0.79 Subunit of the Ada histone acetyltransferase complex, required for structural integrity of the complex
YMR291W 0.79 Putative kinase of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus; YMR291W is not an essential gene
YOR236W 0.78 Dihydrofolate reductase, part of the dTTP biosynthetic pathway, involved in folate metabolism, possibly required for mitochondrial function
YJR147W 0.78 Protein with similarity to heat shock transcription factors; overexpression suppresses the pseudohyphal filamentation defect of a diploid mep1 mep2 homozygous null mutant
YGR121C 0.78 Ammonium permease; belongs to a ubiquitous family of cytoplasmic membrane proteins that transport only ammonium (NH4+); expression is under the nitrogen catabolite repression regulation
YOR186C-A 0.78 Identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching
YDR232W 0.78 5-aminolevulinate synthase, catalyzes the first step in the heme biosynthetic pathway; an N-terminal signal sequence is required for localization to the mitochondrial matrix; expression is regulated by Hap2p-Hap3p

Network of associatons between targets according to the STRING database.

First level regulatory network of YGR067C

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.5 9.9 GO:0015804 neutral amino acid transport(GO:0015804)
1.6 4.9 GO:0009437 amino-acid betaine metabolic process(GO:0006577) carnitine metabolic process(GO:0009437)
1.5 4.4 GO:0015755 fructose transport(GO:0015755)
1.4 5.6 GO:0006848 pyruvate transport(GO:0006848)
1.3 5.1 GO:0006482 protein demethylation(GO:0006482) protein dealkylation(GO:0008214) histone demethylation(GO:0016577) demethylation(GO:0070988)
1.2 6.1 GO:0015793 glycerol transport(GO:0015793)
1.0 6.0 GO:0000128 flocculation(GO:0000128) flocculation via cell wall protein-carbohydrate interaction(GO:0000501)
1.0 3.9 GO:0015976 carbon utilization(GO:0015976)
1.0 2.9 GO:0006068 ethanol catabolic process(GO:0006068) primary alcohol catabolic process(GO:0034310)
1.0 2.9 GO:0005993 trehalose catabolic process(GO:0005993)
0.8 2.5 GO:0032780 negative regulation of ATPase activity(GO:0032780)
0.8 3.3 GO:0019563 alditol catabolic process(GO:0019405) glycerol catabolic process(GO:0019563)
0.8 4.0 GO:0061416 regulation of transcription from RNA polymerase II promoter in response to salt stress(GO:0061416)
0.8 6.1 GO:0015891 siderophore transport(GO:0015891)
0.8 2.3 GO:0051469 vesicle fusion with vacuole(GO:0051469)
0.7 0.7 GO:0019413 acetate biosynthetic process(GO:0019413)
0.7 1.5 GO:0071462 response to water(GO:0009415) cellular response to water stimulus(GO:0071462)
0.7 2.2 GO:0019629 propionate metabolic process(GO:0019541) propionate catabolic process(GO:0019543) short-chain fatty acid catabolic process(GO:0019626) propionate catabolic process, 2-methylcitrate cycle(GO:0019629)
0.7 0.7 GO:0043902 positive regulation of multi-organism process(GO:0043902)
0.6 13.5 GO:0008645 hexose transport(GO:0008645) monosaccharide transport(GO:0015749)
0.6 1.9 GO:0035948 regulation of gluconeogenesis by regulation of transcription from RNA polymerase II promoter(GO:0035947) positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948) regulation of transcription from RNA polymerase II promoter by a nonfermentable carbon source(GO:0061413) positive regulation of transcription from RNA polymerase II promoter by a nonfermentable carbon source(GO:0061414)
0.6 1.8 GO:0006624 vacuolar protein processing(GO:0006624) multivesicular body organization(GO:0036257)
0.6 5.9 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.6 11.2 GO:0005978 glycogen biosynthetic process(GO:0005978)
0.5 2.6 GO:0006102 isocitrate metabolic process(GO:0006102)
0.5 1.9 GO:0001324 age-dependent general metabolic decline involved in chronological cell aging(GO:0001323) age-dependent response to oxidative stress involved in chronological cell aging(GO:0001324)
0.5 1.4 GO:0052547 negative regulation of peptidase activity(GO:0010466) regulation of peptidase activity(GO:0052547)
0.5 4.1 GO:0006882 cellular zinc ion homeostasis(GO:0006882) zinc ion homeostasis(GO:0055069)
0.5 2.3 GO:0032071 regulation of deoxyribonuclease activity(GO:0032070) regulation of endodeoxyribonuclease activity(GO:0032071)
0.4 0.4 GO:0006824 cobalt ion transport(GO:0006824)
0.4 1.7 GO:0030969 mRNA splicing via endonucleolytic cleavage and ligation involved in unfolded protein response(GO:0030969) IRE1-mediated unfolded protein response(GO:0036498) mRNA splicing, via endonucleolytic cleavage and ligation(GO:0070054)
0.4 1.2 GO:0072488 ammonium transmembrane transport(GO:0072488)
0.4 1.5 GO:0006527 arginine catabolic process(GO:0006527)
0.4 2.3 GO:0043457 regulation of cellular respiration(GO:0043457)
0.4 1.5 GO:0015855 pyrimidine nucleobase transport(GO:0015855)
0.4 1.1 GO:0006688 glycosphingolipid biosynthetic process(GO:0006688)
0.3 1.4 GO:0071456 cellular response to hypoxia(GO:0071456)
0.3 2.7 GO:0045721 negative regulation of gluconeogenesis(GO:0045721)
0.3 3.0 GO:0070086 ubiquitin-dependent endocytosis(GO:0070086)
0.3 0.6 GO:0097201 negative regulation of transcription from RNA polymerase II promoter in response to stress(GO:0097201)
0.3 0.9 GO:0031292 gene conversion at mating-type locus, DNA double-strand break processing(GO:0031292)
0.3 0.9 GO:0090527 actin filament reorganization involved in cell cycle(GO:0030037) actin filament reorganization(GO:0090527)
0.3 0.9 GO:0006545 glycine biosynthetic process(GO:0006545)
0.3 2.1 GO:0000023 maltose metabolic process(GO:0000023)
0.3 1.4 GO:0006121 mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
0.3 1.1 GO:0006103 2-oxoglutarate metabolic process(GO:0006103)
0.3 0.8 GO:0042843 D-xylose catabolic process(GO:0042843)
0.3 1.1 GO:0006285 base-excision repair, AP site formation(GO:0006285)
0.3 1.0 GO:0006108 malate metabolic process(GO:0006108)
0.2 0.7 GO:0032056 positive regulation of translation in response to stress(GO:0032056)
0.2 0.7 GO:0042743 hydrogen peroxide metabolic process(GO:0042743) hydrogen peroxide catabolic process(GO:0042744)
0.2 0.9 GO:0006083 acetate metabolic process(GO:0006083)
0.2 0.7 GO:0071475 cellular hyperosmotic salinity response(GO:0071475)
0.2 0.9 GO:1901925 cellular response to biotic stimulus(GO:0071216) response to cell cycle checkpoint signaling(GO:0072396) response to mitotic cell cycle checkpoint signaling(GO:0072414) response to spindle checkpoint signaling(GO:0072417) response to mitotic spindle checkpoint signaling(GO:0072476) response to mitotic cell cycle spindle assembly checkpoint signaling(GO:0072479) response to spindle assembly checkpoint signaling(GO:0072485) negative regulation of protein import into nucleus during spindle assembly checkpoint(GO:1901925)
0.2 1.4 GO:0071322 cellular response to carbohydrate stimulus(GO:0071322)
0.2 0.7 GO:0017006 protein-heme linkage(GO:0017003) protein-tetrapyrrole linkage(GO:0017006) cytochrome c-heme linkage(GO:0018063)
0.2 2.4 GO:0000722 telomere maintenance via recombination(GO:0000722)
0.2 0.9 GO:0051126 negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316) negative regulation of actin nucleation(GO:0051126)
0.2 1.0 GO:0071931 positive regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0071931)
0.2 0.6 GO:0034090 maintenance of meiotic sister chromatid cohesion(GO:0034090)
0.2 0.6 GO:0015740 C4-dicarboxylate transport(GO:0015740)
0.2 0.9 GO:0033683 nucleotide-excision repair, DNA incision(GO:0033683)
0.2 0.7 GO:0006075 (1->3)-beta-D-glucan biosynthetic process(GO:0006075)
0.2 0.6 GO:0071629 cytoplasm-associated proteasomal ubiquitin-dependent protein catabolic process(GO:0071629)
0.2 0.8 GO:0090294 nitrogen catabolite activation of transcription from RNA polymerase II promoter(GO:0001080) nitrogen catabolite activation of transcription(GO:0090294)
0.1 0.4 GO:0043419 urea metabolic process(GO:0019627) urea catabolic process(GO:0043419)
0.1 7.2 GO:0006631 fatty acid metabolic process(GO:0006631)
0.1 0.5 GO:2000284 positive regulation of cellular amino acid biosynthetic process(GO:2000284)
0.1 0.6 GO:0046487 glyoxylate metabolic process(GO:0046487)
0.1 0.5 GO:0051101 positive regulation of DNA binding(GO:0043388) regulation of DNA binding(GO:0051101)
0.1 1.6 GO:0033617 mitochondrial respiratory chain complex IV assembly(GO:0033617)
0.1 0.4 GO:0032443 regulation of steroid metabolic process(GO:0019218) regulation of ergosterol biosynthetic process(GO:0032443) regulation of steroid biosynthetic process(GO:0050810)
0.1 0.5 GO:0046341 CDP-diacylglycerol biosynthetic process(GO:0016024) CDP-diacylglycerol metabolic process(GO:0046341)
0.1 0.5 GO:0051303 meiotic telomere clustering(GO:0045141) establishment of chromosome localization(GO:0051303) chromosome localization to nuclear envelope involved in homologous chromosome segregation(GO:0090220)
0.1 0.8 GO:0043328 protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328)
0.1 1.9 GO:0009228 thiamine biosynthetic process(GO:0009228) thiamine-containing compound biosynthetic process(GO:0042724)
0.1 1.2 GO:0015718 monocarboxylic acid transport(GO:0015718)
0.1 0.9 GO:0000321 re-entry into mitotic cell cycle after pheromone arrest(GO:0000321)
0.1 0.2 GO:0031335 regulation of sulfur amino acid metabolic process(GO:0031335)
0.1 1.0 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.1 0.7 GO:0070058 tRNA gene clustering(GO:0070058)
0.1 0.6 GO:0006855 drug transmembrane transport(GO:0006855)
0.1 0.2 GO:0051098 regulation of binding(GO:0051098)
0.1 0.3 GO:0044209 AMP salvage(GO:0044209)
0.1 2.6 GO:0043248 proteasome assembly(GO:0043248)
0.1 0.7 GO:0097034 mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.1 0.2 GO:0034033 coenzyme A biosynthetic process(GO:0015937) nucleoside bisphosphate biosynthetic process(GO:0033866) ribonucleoside bisphosphate biosynthetic process(GO:0034030) purine nucleoside bisphosphate biosynthetic process(GO:0034033)
0.1 1.7 GO:0042493 response to drug(GO:0042493)
0.1 0.4 GO:0031135 negative regulation of conjugation(GO:0031135) negative regulation of conjugation with cellular fusion(GO:0031138) negative regulation of multi-organism process(GO:0043901)
0.1 0.1 GO:0046185 aldehyde catabolic process(GO:0046185)
0.1 0.5 GO:0046352 disaccharide catabolic process(GO:0046352)
0.1 0.1 GO:0033241 regulation of cellular amine catabolic process(GO:0033241)
0.1 0.4 GO:0007039 protein catabolic process in the vacuole(GO:0007039)
0.1 0.3 GO:0071902 positive regulation of cell death(GO:0010942) positive regulation of apoptotic process(GO:0043065) positive regulation of programmed cell death(GO:0043068) positive regulation of protein serine/threonine kinase activity(GO:0071902)
0.1 0.3 GO:0010688 negative regulation of ribosomal protein gene transcription from RNA polymerase II promoter(GO:0010688)
0.1 0.2 GO:0006000 fructose metabolic process(GO:0006000)
0.1 0.5 GO:0006279 premeiotic DNA replication(GO:0006279)
0.1 0.2 GO:0016320 endoplasmic reticulum membrane fusion(GO:0016320)
0.1 0.2 GO:0006390 transcription from mitochondrial promoter(GO:0006390)
0.1 0.2 GO:0051131 chaperone-mediated protein complex assembly(GO:0051131)
0.1 0.2 GO:0055078 cellular sodium ion homeostasis(GO:0006883) sodium ion homeostasis(GO:0055078)
0.1 1.1 GO:0007129 synapsis(GO:0007129)
0.1 0.1 GO:0006827 high-affinity iron ion transmembrane transport(GO:0006827)
0.1 0.3 GO:0000949 aromatic amino acid family catabolic process to alcohol via Ehrlich pathway(GO:0000949)
0.1 0.1 GO:0045980 negative regulation of nucleotide metabolic process(GO:0045980)
0.1 0.4 GO:0031507 heterochromatin assembly(GO:0031507)
0.1 0.3 GO:0046461 triglyceride catabolic process(GO:0019433) neutral lipid catabolic process(GO:0046461) acylglycerol catabolic process(GO:0046464)
0.1 1.0 GO:0006513 protein monoubiquitination(GO:0006513)
0.1 0.3 GO:0046688 response to copper ion(GO:0046688)
0.1 1.2 GO:0006094 gluconeogenesis(GO:0006094)
0.1 0.1 GO:0072350 tricarboxylic acid metabolic process(GO:0072350)
0.1 2.3 GO:0051123 RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123)
0.1 0.2 GO:0060237 regulation of fungal-type cell wall organization(GO:0060237)
0.1 0.4 GO:0006089 lactate metabolic process(GO:0006089)
0.1 0.5 GO:0046686 response to cadmium ion(GO:0046686)
0.1 0.1 GO:0001178 regulation of transcriptional start site selection at RNA polymerase II promoter(GO:0001178)
0.1 1.0 GO:0016575 histone deacetylation(GO:0016575)
0.1 3.2 GO:0007031 peroxisome organization(GO:0007031)
0.1 0.7 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.1 0.1 GO:0090630 activation of GTPase activity(GO:0090630)
0.1 0.1 GO:0009743 response to carbohydrate(GO:0009743) response to hexose(GO:0009746) response to glucose(GO:0009749) response to monosaccharide(GO:0034284)
0.0 0.2 GO:0006047 UDP-N-acetylglucosamine metabolic process(GO:0006047) UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.0 0.2 GO:0019933 cAMP-mediated signaling(GO:0019933) cyclic-nucleotide-mediated signaling(GO:0019935)
0.0 1.8 GO:0009060 aerobic respiration(GO:0009060)
0.0 0.2 GO:0000920 cell separation after cytokinesis(GO:0000920)
0.0 0.1 GO:0000117 regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117) positive regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0090282)
0.0 0.1 GO:0006114 glycerol biosynthetic process(GO:0006114) alditol biosynthetic process(GO:0019401)
0.0 0.9 GO:0000422 mitophagy(GO:0000422) mitochondrion disassembly(GO:0061726)
0.0 0.2 GO:0010508 positive regulation of autophagy(GO:0010508) positive regulation of macroautophagy(GO:0016239)
0.0 0.5 GO:0006749 glutathione metabolic process(GO:0006749)
0.0 0.2 GO:0072337 modified amino acid transport(GO:0072337)
0.0 0.1 GO:0051180 vitamin transport(GO:0051180)
0.0 0.3 GO:0030100 regulation of endocytosis(GO:0030100)
0.0 0.2 GO:0045117 azole transport(GO:0045117)
0.0 0.2 GO:0009083 branched-chain amino acid catabolic process(GO:0009083)
0.0 0.7 GO:0007266 Rho protein signal transduction(GO:0007266)
0.0 0.4 GO:0016925 protein sumoylation(GO:0016925)
0.0 0.2 GO:0031032 assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin structure organization(GO:0031032) actomyosin contractile ring organization(GO:0044837)
0.0 0.2 GO:0055088 lipid homeostasis(GO:0055088)
0.0 1.1 GO:0030258 lipid modification(GO:0030258)
0.0 0.4 GO:0001101 response to acid chemical(GO:0001101)
0.0 0.1 GO:0044247 glycogen catabolic process(GO:0005980) glucan catabolic process(GO:0009251) cellular polysaccharide catabolic process(GO:0044247)
0.0 0.2 GO:0070192 chromosome organization involved in meiotic cell cycle(GO:0070192)
0.0 0.2 GO:0033674 positive regulation of kinase activity(GO:0033674)
0.0 0.2 GO:0046501 protoporphyrinogen IX biosynthetic process(GO:0006782) protoporphyrinogen IX metabolic process(GO:0046501)
0.0 0.1 GO:0000751 mitotic cell cycle arrest in response to pheromone(GO:0000751) mitotic cell cycle arrest(GO:0071850)
0.0 0.1 GO:0009410 response to xenobiotic stimulus(GO:0009410)
0.0 0.1 GO:0070911 global genome nucleotide-excision repair(GO:0070911)
0.0 0.2 GO:0042168 porphyrin-containing compound metabolic process(GO:0006778) tetrapyrrole metabolic process(GO:0033013) heme metabolic process(GO:0042168)
0.0 0.1 GO:0070900 mitochondrial tRNA modification(GO:0070900) mitochondrial RNA modification(GO:1900864)
0.0 0.2 GO:0000350 generation of catalytic spliceosome for second transesterification step(GO:0000350)
0.0 0.1 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.0 0.9 GO:0042176 regulation of protein catabolic process(GO:0042176)
0.0 0.3 GO:0032511 late endosome to vacuole transport via multivesicular body sorting pathway(GO:0032511)
0.0 0.1 GO:0061188 regulation of chromatin silencing at rDNA(GO:0061187) negative regulation of chromatin silencing at rDNA(GO:0061188)
0.0 0.2 GO:0034087 establishment of sister chromatid cohesion(GO:0034085) establishment of mitotic sister chromatid cohesion(GO:0034087)
0.0 0.4 GO:0006986 response to unfolded protein(GO:0006986)
0.0 0.1 GO:0000390 spliceosomal complex disassembly(GO:0000390)
0.0 0.1 GO:0015809 arginine transport(GO:0015809)
0.0 0.2 GO:0030174 regulation of DNA-dependent DNA replication initiation(GO:0030174)
0.0 0.1 GO:0019932 second-messenger-mediated signaling(GO:0019932)
0.0 0.4 GO:0006378 mRNA polyadenylation(GO:0006378)
0.0 0.3 GO:0016579 protein deubiquitination(GO:0016579)
0.0 0.1 GO:0006816 calcium ion transport(GO:0006816)
0.0 0.1 GO:0018345 protein palmitoylation(GO:0018345)
0.0 0.0 GO:0008216 spermidine metabolic process(GO:0008216)
0.0 0.2 GO:0034629 cellular protein complex localization(GO:0034629)
0.0 0.1 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 7.9 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.8 3.1 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.7 3.0 GO:0031315 extrinsic component of mitochondrial outer membrane(GO:0031315)
0.6 1.8 GO:0032585 multivesicular body membrane(GO:0032585)
0.6 2.9 GO:0030062 mitochondrial tricarboxylic acid cycle enzyme complex(GO:0030062)
0.5 2.0 GO:0030287 cell wall-bounded periplasmic space(GO:0030287)
0.5 3.3 GO:0034657 GID complex(GO:0034657)
0.5 1.4 GO:0031422 RecQ helicase-Topo III complex(GO:0031422)
0.4 1.5 GO:0042597 periplasmic space(GO:0042597)
0.3 3.1 GO:0045275 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.3 0.3 GO:0045239 tricarboxylic acid cycle enzyme complex(GO:0045239)
0.3 1.4 GO:0045281 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) mitochondrial inner membrane protein insertion complex(GO:0042721) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.2 0.9 GO:0033309 SBF transcription complex(GO:0033309)
0.2 0.6 GO:0045265 mitochondrial proton-transporting ATP synthase, stator stalk(GO:0000274) proton-transporting ATP synthase, stator stalk(GO:0045265)
0.2 0.6 GO:0031201 SNARE complex(GO:0031201)
0.2 1.2 GO:0034967 Set3 complex(GO:0034967)
0.2 1.3 GO:0000112 nucleotide-excision repair factor 3 complex(GO:0000112)
0.2 8.8 GO:0031225 anchored component of membrane(GO:0031225)
0.2 0.7 GO:0000148 1,3-beta-D-glucan synthase complex(GO:0000148)
0.2 0.5 GO:0030870 Mre11 complex(GO:0030870)
0.2 0.2 GO:0031931 TORC1 complex(GO:0031931)
0.2 1.9 GO:0045259 mitochondrial proton-transporting ATP synthase complex(GO:0005753) proton-transporting ATP synthase complex(GO:0045259)
0.2 3.9 GO:0098852 fungal-type vacuole membrane(GO:0000329) lytic vacuole membrane(GO:0098852)
0.2 2.8 GO:0031306 intrinsic component of mitochondrial outer membrane(GO:0031306) integral component of mitochondrial outer membrane(GO:0031307)
0.2 1.5 GO:0030677 ribonuclease P complex(GO:0030677)
0.1 7.5 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.1 0.8 GO:0070772 PAS complex(GO:0070772)
0.1 0.7 GO:0032545 CURI complex(GO:0032545)
0.1 1.3 GO:0000974 Prp19 complex(GO:0000974)
0.1 1.7 GO:0005619 ascospore wall(GO:0005619)
0.1 3.2 GO:0005887 integral component of plasma membrane(GO:0005887)
0.1 0.8 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.1 2.3 GO:0070847 core mediator complex(GO:0070847)
0.1 16.1 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.1 0.3 GO:0005795 Golgi stack(GO:0005795)
0.1 1.5 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.1 0.4 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.1 0.7 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
0.1 0.2 GO:0000126 transcription factor TFIIIB complex(GO:0000126)
0.1 0.3 GO:0033100 NuA3 histone acetyltransferase complex(GO:0033100) H3 histone acetyltransferase complex(GO:0070775)
0.0 0.8 GO:0019897 extrinsic component of plasma membrane(GO:0019897)
0.0 0.3 GO:0000133 polarisome(GO:0000133)
0.0 0.2 GO:0000817 COMA complex(GO:0000817)
0.0 0.6 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0 0.3 GO:0033263 CORVET complex(GO:0033263)
0.0 0.2 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 0.1 GO:0000113 nucleotide-excision repair factor 4 complex(GO:0000113)
0.0 0.1 GO:0071008 U2-type post-mRNA release spliceosomal complex(GO:0071008)
0.0 0.8 GO:0000323 storage vacuole(GO:0000322) lytic vacuole(GO:0000323) fungal-type vacuole(GO:0000324)
0.0 0.1 GO:0005796 Golgi lumen(GO:0005796)
0.0 0.1 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 0.2 GO:0000328 fungal-type vacuole lumen(GO:0000328)
0.0 0.1 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.0 0.2 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 0.4 GO:0030014 CCR4-NOT complex(GO:0030014)
0.0 0.2 GO:0032221 Rpd3S complex(GO:0032221)
0.0 0.1 GO:0030907 MBF transcription complex(GO:0030907)
0.0 0.1 GO:0031901 early endosome membrane(GO:0031901)
0.0 0.4 GO:0000940 condensed chromosome outer kinetochore(GO:0000940) condensed nuclear chromosome outer kinetochore(GO:0000942)
0.0 1.2 GO:0019898 extrinsic component of membrane(GO:0019898)
0.0 0.2 GO:0031907 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 0.1 GO:0000799 condensin complex(GO:0000796) nuclear condensin complex(GO:0000799)
0.0 0.1 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.0 0.3 GO:0046695 SLIK (SAGA-like) complex(GO:0046695)
0.0 0.1 GO:0005825 half bridge of spindle pole body(GO:0005825)
0.0 1.0 GO:0000151 ubiquitin ligase complex(GO:0000151)
0.0 0.1 GO:0045334 AP-2 adaptor complex(GO:0030122) clathrin coat of endocytic vesicle(GO:0030128) endocytic vesicle(GO:0030139) endocytic vesicle membrane(GO:0030666) clathrin-coated endocytic vesicle membrane(GO:0030669) clathrin-coated endocytic vesicle(GO:0045334)
0.0 0.1 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.0 0.2 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 9.1 GO:0016021 integral component of membrane(GO:0016021)
0.0 0.0 GO:0072380 ER membrane insertion complex(GO:0072379) TRC complex(GO:0072380)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.9 9.7 GO:0015295 solute:proton symporter activity(GO:0015295)
1.8 7.2 GO:0015193 L-proline transmembrane transporter activity(GO:0015193)
1.6 4.9 GO:0016406 carnitine O-acetyltransferase activity(GO:0004092) carnitine O-acyltransferase activity(GO:0016406)
1.6 4.7 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
1.3 5.2 GO:0005537 mannose binding(GO:0005537)
1.0 4.0 GO:0004396 hexokinase activity(GO:0004396)
1.0 3.0 GO:0047066 phospholipid-hydroperoxide glutathione peroxidase activity(GO:0047066)
1.0 2.9 GO:0015927 alpha,alpha-trehalase activity(GO:0004555) trehalase activity(GO:0015927)
0.9 2.6 GO:0050833 pyruvate transmembrane transporter activity(GO:0050833)
0.6 8.7 GO:0015578 fructose transmembrane transporter activity(GO:0005353) mannose transmembrane transporter activity(GO:0015578)
0.6 7.4 GO:0008599 protein phosphatase type 1 regulator activity(GO:0008599)
0.6 3.0 GO:0050308 sugar-phosphatase activity(GO:0050308)
0.5 2.2 GO:0001097 TFIIH-class transcription factor binding(GO:0001097)
0.5 2.6 GO:0004448 isocitrate dehydrogenase activity(GO:0004448)
0.5 1.0 GO:0042947 alpha-glucoside transmembrane transporter activity(GO:0015151) glucoside transmembrane transporter activity(GO:0042947)
0.5 1.4 GO:0048038 quinone binding(GO:0048038)
0.5 2.8 GO:0090599 alpha-glucosidase activity(GO:0090599)
0.5 1.4 GO:0004866 endopeptidase inhibitor activity(GO:0004866) peptidase inhibitor activity(GO:0030414)
0.4 2.1 GO:0050253 triglyceride lipase activity(GO:0004806) retinyl-palmitate esterase activity(GO:0050253)
0.4 1.7 GO:0001094 TFIID-class transcription factor binding(GO:0001094)
0.4 2.3 GO:0004029 aldehyde dehydrogenase (NAD) activity(GO:0004029) aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030)
0.4 0.4 GO:0032452 histone demethylase activity(GO:0032452)
0.3 1.4 GO:0015294 solute:cation symporter activity(GO:0015294)
0.3 1.0 GO:0030060 L-malate dehydrogenase activity(GO:0030060)
0.3 5.7 GO:0046906 heme binding(GO:0020037) tetrapyrrole binding(GO:0046906)
0.3 6.0 GO:0015297 antiporter activity(GO:0015297)
0.3 2.2 GO:0016833 oxo-acid-lyase activity(GO:0016833)
0.3 2.4 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.3 1.0 GO:0015101 organic cation transmembrane transporter activity(GO:0015101)
0.2 0.7 GO:0003843 1,3-beta-D-glucan synthase activity(GO:0003843)
0.2 0.9 GO:0016624 oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor(GO:0016624)
0.2 1.5 GO:0008519 ammonium transmembrane transporter activity(GO:0008519)
0.2 1.1 GO:0019104 DNA N-glycosylase activity(GO:0019104)
0.2 2.6 GO:0005199 structural constituent of cell wall(GO:0005199)
0.2 0.9 GO:0000156 phosphorelay response regulator activity(GO:0000156)
0.2 0.8 GO:0016405 CoA-ligase activity(GO:0016405) acid-thiol ligase activity(GO:0016878)
0.2 0.8 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.2 3.2 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.2 2.3 GO:0044389 ubiquitin protein ligase binding(GO:0031625) ubiquitin-like protein ligase binding(GO:0044389)
0.2 0.7 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.2 0.9 GO:0008198 ferrous iron binding(GO:0008198)
0.2 0.5 GO:0003691 double-stranded telomeric DNA binding(GO:0003691)
0.2 0.5 GO:0016289 CoA hydrolase activity(GO:0016289)
0.2 1.7 GO:0099600 transmembrane signaling receptor activity(GO:0004888) signaling receptor activity(GO:0038023) transmembrane receptor activity(GO:0099600)
0.2 1.5 GO:0004526 ribonuclease P activity(GO:0004526)
0.1 0.4 GO:0004619 phosphoglycerate mutase activity(GO:0004619)
0.1 2.2 GO:0016831 carboxy-lyase activity(GO:0016831)
0.1 1.6 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.1 0.4 GO:0050136 NADH dehydrogenase activity(GO:0003954) NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.1 0.9 GO:0000014 single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.1 0.7 GO:0015038 peptide disulfide oxidoreductase activity(GO:0015037) glutathione disulfide oxidoreductase activity(GO:0015038)
0.1 1.3 GO:0000384 first spliceosomal transesterification activity(GO:0000384)
0.1 2.3 GO:0004857 enzyme inhibitor activity(GO:0004857)
0.1 0.1 GO:0005346 purine ribonucleotide transmembrane transporter activity(GO:0005346)
0.1 1.6 GO:0015616 DNA translocase activity(GO:0015616)
0.1 4.5 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077) transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.1 0.2 GO:0001026 transcription factor activity, core RNA polymerase III binding(GO:0000995) TFIIIB-type transcription factor activity(GO:0001026)
0.1 0.3 GO:0004108 citrate (Si)-synthase activity(GO:0004108) citrate synthase activity(GO:0036440)
0.1 0.3 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.1 0.4 GO:0000099 sulfur amino acid transmembrane transporter activity(GO:0000099)
0.1 0.5 GO:0000400 four-way junction DNA binding(GO:0000400)
0.1 0.2 GO:0000150 recombinase activity(GO:0000150)
0.1 0.9 GO:0043140 ATP-dependent 3'-5' DNA helicase activity(GO:0043140)
0.1 0.7 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.1 0.2 GO:0004724 magnesium-dependent protein serine/threonine phosphatase activity(GO:0004724)
0.1 0.2 GO:1901474 azole transmembrane transporter activity(GO:1901474)
0.1 1.7 GO:0016881 acid-amino acid ligase activity(GO:0016881)
0.1 0.3 GO:0004032 alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.1 0.7 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.1 1.4 GO:0003684 damaged DNA binding(GO:0003684)
0.1 0.8 GO:0016646 oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor(GO:0016646)
0.1 1.6 GO:0003713 transcription coactivator activity(GO:0003713)
0.1 0.2 GO:0098518 polynucleotide phosphatase activity(GO:0098518)
0.1 1.1 GO:0016769 transaminase activity(GO:0008483) transferase activity, transferring nitrogenous groups(GO:0016769)
0.1 0.5 GO:0000293 ferric-chelate reductase activity(GO:0000293) oxidoreductase activity, oxidizing metal ions, NAD or NADP as acceptor(GO:0016723)
0.1 0.2 GO:0016668 oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor(GO:0016668)
0.1 0.5 GO:0001191 transcriptional repressor activity, RNA polymerase II transcription factor binding(GO:0001191)
0.1 0.3 GO:0004559 alpha-mannosidase activity(GO:0004559) mannosidase activity(GO:0015923)
0.1 0.2 GO:0050839 cell adhesion molecule binding(GO:0050839)
0.1 1.0 GO:0003678 DNA helicase activity(GO:0003678)
0.1 0.5 GO:0016413 O-acetyltransferase activity(GO:0016413)
0.1 0.5 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
0.1 0.2 GO:0034596 phosphatidylinositol phosphate 4-phosphatase activity(GO:0034596) phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812)
0.0 0.2 GO:0016417 S-acyltransferase activity(GO:0016417)
0.0 0.1 GO:0016832 aldehyde-lyase activity(GO:0016832)
0.0 0.1 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.0 0.2 GO:0017022 myosin binding(GO:0017022)
0.0 0.1 GO:0004457 lactate dehydrogenase activity(GO:0004457) oxidoreductase activity, acting on the CH-OH group of donors, cytochrome as acceptor(GO:0016898)
0.0 0.9 GO:0016836 hydro-lyase activity(GO:0016836)
0.0 0.2 GO:0017048 Rho GTPase binding(GO:0017048)
0.0 2.1 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.0 0.1 GO:0015293 symporter activity(GO:0015293)
0.0 0.1 GO:0008172 S-methyltransferase activity(GO:0008172)
0.0 0.2 GO:0003993 acid phosphatase activity(GO:0003993)
0.0 0.4 GO:0035064 methylated histone binding(GO:0035064)
0.0 0.1 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.1 GO:0004663 Rab geranylgeranyltransferase activity(GO:0004663)
0.0 0.6 GO:0005509 calcium ion binding(GO:0005509)
0.0 0.3 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.0 0.3 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 0.3 GO:0031369 translation initiation factor binding(GO:0031369)
0.0 2.4 GO:0032403 protein complex binding(GO:0032403)
0.0 0.2 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.0 0.4 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983) transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.0 0.5 GO:0005507 copper ion binding(GO:0005507)
0.0 0.2 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 0.1 GO:0005337 nucleoside transmembrane transporter activity(GO:0005337)
0.0 0.4 GO:0050660 flavin adenine dinucleotide binding(GO:0050660)
0.0 0.6 GO:0004871 signal transducer activity(GO:0004871)
0.0 0.2 GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen(GO:0016705)
0.0 1.0 GO:0005096 GTPase activator activity(GO:0005096)
0.0 0.0 GO:0016530 metallochaperone activity(GO:0016530)
0.0 0.4 GO:0004843 obsolete ubiquitin thiolesterase activity(GO:0004221) thiol-dependent ubiquitin-specific protease activity(GO:0004843) thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.0 0.2 GO:0016409 palmitoyltransferase activity(GO:0016409)
0.0 0.2 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 0.0 GO:0045118 azole transporter activity(GO:0045118)
0.0 0.1 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.1 GO:0001104 RNA polymerase II transcription cofactor activity(GO:0001104)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.1 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.2 0.5 PID IL4 2PATHWAY IL4-mediated signaling events
0.2 0.5 PID ATM PATHWAY ATM pathway
0.2 0.5 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.2 0.5 PID ERBB4 PATHWAY ErbB4 signaling events
0.1 0.2 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.1 0.2 PID AR PATHWAY Coregulation of Androgen receptor activity
0.1 0.5 PID FANCONI PATHWAY Fanconi anemia pathway
0.1 0.2 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.0 38.4 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 3.1 REACTOME GLUCOSE METABOLISM Genes involved in Glucose metabolism
0.3 1.1 REACTOME DOUBLE STRAND BREAK REPAIR Genes involved in Double-Strand Break Repair
0.2 0.4 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.2 0.5 REACTOME PYRUVATE METABOLISM AND CITRIC ACID TCA CYCLE Genes involved in Pyruvate metabolism and Citric Acid (TCA) cycle
0.2 0.5 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.1 0.2 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.0 0.7 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 0.2 REACTOME CHROMOSOME MAINTENANCE Genes involved in Chromosome Maintenance
0.0 0.1 REACTOME DIABETES PATHWAYS Genes involved in Diabetes pathways
0.0 35.3 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 0.2 REACTOME TRANSCRIPTION Genes involved in Transcription