Results for YGR067C
Z-value: 0.87
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Transcription factors associated with YGR067C
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
| S000003299 | Putative protein of unknown function |
Activity-expression correlation:
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| YGR067C Show fit | 11.66 |
Putative protein of unknown function; contains a zinc finger motif similar to that of Adr1p |
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| YOR348C Show fit | 9.72 |
Proline permease, required for high-affinity transport of proline; also transports the toxic proline analog azetidine-2-carboxylate (AzC); PUT4 transcription is repressed in ammonia-grown cells |
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| YOR100C Show fit | 9.27 |
Mitochondrial inner membrane carnitine transporter, required for carnitine-dependent transport of acetyl-CoA from peroxisomes to mitochondria during fatty acid beta-oxidation |
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| YDR536W Show fit | 6.45 |
Glycerol proton symporter of the plasma membrane, subject to glucose-induced inactivation, strongly but transiently induced when cells are subjected to osmotic shock |
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| YHR217C Show fit | 5.82 |
Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; located in the telomeric region TEL08R. |
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| YDR342C Show fit | 5.77 |
High-affinity glucose transporter of the major facilitator superfamily, nearly identical to Hxt6p, expressed at high basal levels relative to other HXTs, expression repressed by high glucose levels |
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| YLR312C Show fit | 5.73 |
Protein of unknown function; null mutant quiescent and non-quiescent cells exhibit reduced reproductive capacity |
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| YKL163W Show fit | 5.24 |
O-glycosylated covalently-bound cell wall protein required for cell wall stability; expression is cell cycle regulated, peaking in M/G1 and also subject to regulation by the cell integrity pathway |
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| YMR107W Show fit | 5.12 |
Protein required for survival at high temperature during stationary phase; not required for growth on nonfermentable carbon sources |
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| YFL052W Show fit | 4.99 |
Putative zinc cluster protein that contains a DNA binding domain; null mutant sensitive to calcofluor white, low osmolarity and heat, suggesting a role for YFL052Wp in cell wall integrity |
Network of associatons between targets according to the STRING database.
First level regulatory network of YGR067C
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.6 | 13.5 | GO:0008645 | hexose transport(GO:0008645) monosaccharide transport(GO:0015749) |
| 0.6 | 11.2 | GO:0005978 | glycogen biosynthetic process(GO:0005978) |
| 2.5 | 9.9 | GO:0015804 | neutral amino acid transport(GO:0015804) |
| 0.1 | 7.2 | GO:0006631 | fatty acid metabolic process(GO:0006631) |
| 1.2 | 6.1 | GO:0015793 | glycerol transport(GO:0015793) |
| 0.8 | 6.1 | GO:0015891 | siderophore transport(GO:0015891) |
| 1.0 | 6.0 | GO:0000128 | flocculation(GO:0000128) flocculation via cell wall protein-carbohydrate interaction(GO:0000501) |
| 0.6 | 5.9 | GO:0006122 | mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122) |
| 1.4 | 5.6 | GO:0006848 | pyruvate transport(GO:0006848) |
| 1.3 | 5.1 | GO:0006482 | protein demethylation(GO:0006482) protein dealkylation(GO:0008214) histone demethylation(GO:0016577) demethylation(GO:0070988) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 16.1 | GO:0005743 | mitochondrial inner membrane(GO:0005743) |
| 0.0 | 9.1 | GO:0016021 | integral component of membrane(GO:0016021) |
| 0.2 | 8.8 | GO:0031225 | anchored component of membrane(GO:0031225) |
| 1.0 | 7.9 | GO:0000164 | protein phosphatase type 1 complex(GO:0000164) |
| 0.1 | 7.5 | GO:0005758 | mitochondrial intermembrane space(GO:0005758) |
| 0.2 | 3.9 | GO:0098852 | fungal-type vacuole membrane(GO:0000329) lytic vacuole membrane(GO:0098852) |
| 0.5 | 3.3 | GO:0034657 | GID complex(GO:0034657) |
| 0.1 | 3.2 | GO:0005887 | integral component of plasma membrane(GO:0005887) |
| 0.8 | 3.1 | GO:0016602 | CCAAT-binding factor complex(GO:0016602) |
| 0.3 | 3.1 | GO:0045275 | mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.9 | 9.7 | GO:0015295 | solute:proton symporter activity(GO:0015295) |
| 0.6 | 8.7 | GO:0015578 | fructose transmembrane transporter activity(GO:0005353) mannose transmembrane transporter activity(GO:0015578) |
| 0.6 | 7.4 | GO:0008599 | protein phosphatase type 1 regulator activity(GO:0008599) |
| 1.8 | 7.2 | GO:0015193 | L-proline transmembrane transporter activity(GO:0015193) |
| 0.3 | 6.0 | GO:0015297 | antiporter activity(GO:0015297) |
| 0.3 | 5.7 | GO:0046906 | heme binding(GO:0020037) tetrapyrrole binding(GO:0046906) |
| 1.3 | 5.2 | GO:0005537 | mannose binding(GO:0005537) |
| 1.6 | 4.9 | GO:0016406 | carnitine O-acetyltransferase activity(GO:0004092) carnitine O-acyltransferase activity(GO:0016406) |
| 1.6 | 4.7 | GO:0051864 | histone demethylase activity (H3-K36 specific)(GO:0051864) |
| 0.1 | 4.5 | GO:0001077 | transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077) transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 38.4 | PID P53 DOWNSTREAM PATHWAY | Direct p53 effectors |
| 0.7 | 2.1 | PID HNF3B PATHWAY | FOXA2 and FOXA3 transcription factor networks |
| 0.2 | 0.5 | PID IL4 2PATHWAY | IL4-mediated signaling events |
| 0.2 | 0.5 | PID ATM PATHWAY | ATM pathway |
| 0.2 | 0.5 | SA G1 AND S PHASES | Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition. |
| 0.2 | 0.5 | PID ERBB4 PATHWAY | ErbB4 signaling events |
| 0.1 | 0.5 | PID FANCONI PATHWAY | Fanconi anemia pathway |
| 0.1 | 0.2 | NABA ECM REGULATORS | Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix |
| 0.1 | 0.2 | PID AR PATHWAY | Coregulation of Androgen receptor activity |
| 0.1 | 0.2 | PID ERA GENOMIC PATHWAY | Validated nuclear estrogen receptor alpha network |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 35.3 | REACTOME CHONDROITIN SULFATE BIOSYNTHESIS | Genes involved in Chondroitin sulfate biosynthesis |
| 0.3 | 3.1 | REACTOME GLUCOSE METABOLISM | Genes involved in Glucose metabolism |
| 0.3 | 1.1 | REACTOME DOUBLE STRAND BREAK REPAIR | Genes involved in Double-Strand Break Repair |
| 0.0 | 0.7 | REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION | Genes involved in Antigen processing: Ubiquitination & Proteasome degradation |
| 0.2 | 0.5 | REACTOME PYRUVATE METABOLISM AND CITRIC ACID TCA CYCLE | Genes involved in Pyruvate metabolism and Citric Acid (TCA) cycle |
| 0.2 | 0.5 | REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING | Genes involved in Downregulation of ERBB2:ERBB3 signaling |
| 0.2 | 0.4 | REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S | Genes involved in Activation of Chaperone Genes by XBP1(S) |
| 0.1 | 0.2 | REACTOME MEIOTIC SYNAPSIS | Genes involved in Meiotic Synapsis |
| 0.0 | 0.2 | REACTOME CHROMOSOME MAINTENANCE | Genes involved in Chromosome Maintenance |
| 0.0 | 0.2 | REACTOME TRANSCRIPTION | Genes involved in Transcription |