Results for YER184C
Z-value: 0.80
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Transcription factors associated with YER184C
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
| S000000986 | Putative zinc cluster protein |
Activity-expression correlation:
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| YOR348C Show fit | 7.23 |
Proline permease, required for high-affinity transport of proline; also transports the toxic proline analog azetidine-2-carboxylate (AzC); PUT4 transcription is repressed in ammonia-grown cells |
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| YAR035W Show fit | 6.37 |
Outer mitochondrial carnitine acetyltransferase, minor ethanol-inducible enzyme involved in transport of activated acyl groups from the cytoplasm into the mitochondrial matrix; phosphorylated |
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| YER065C Show fit | 5.87 |
Isocitrate lyase, catalyzes the formation of succinate and glyoxylate from isocitrate, a key reaction of the glyoxylate cycle; expression of ICL1 is induced by growth on ethanol and repressed by growth on glucose |
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| YLR377C Show fit | 4.96 |
Fructose-1,6-bisphosphatase, key regulatory enzyme in the gluconeogenesis pathway, required for glucose metabolism |
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| YPL026C Show fit | 4.94 |
Putative serine/threonine protein kinase; involved in the adaptation to low concentrations of glucose independent of the SNF3 regulated pathway |
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| YLR402W Show fit | 4.91 |
Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data |
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| YPL024W Show fit | 4.79 |
Involved in response to DNA damage; null mutants have increased rates of recombination and delayed S phase; interacts physically and genetically with Sgs1p (RecQ family member) and Top3p (topoisomerase III) |
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| YLR122C Show fit | 4.79 |
Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the dubious ORF YLR123C |
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| YBL043W Show fit | 4.55 |
Non-essential protein of unknown function; induced by treatment with 8-methoxypsoralen and UVA irradiation |
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| YAR053W Show fit | 4.31 |
Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data |
Network of associatons between targets according to the STRING database.
First level regulatory network of YER184C
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.6 | 14.5 | GO:0006097 | glyoxylate cycle(GO:0006097) |
| 0.8 | 7.2 | GO:0045721 | negative regulation of gluconeogenesis(GO:0045721) |
| 0.2 | 7.1 | GO:0009060 | aerobic respiration(GO:0009060) |
| 0.7 | 6.6 | GO:0034284 | response to hexose(GO:0009746) response to glucose(GO:0009749) response to monosaccharide(GO:0034284) |
| 2.1 | 6.4 | GO:0009437 | amino-acid betaine metabolic process(GO:0006577) carnitine metabolic process(GO:0009437) |
| 1.5 | 6.1 | GO:0015804 | neutral amino acid transport(GO:0015804) |
| 1.3 | 5.2 | GO:0051101 | positive regulation of DNA binding(GO:0043388) regulation of DNA binding(GO:0051101) |
| 0.7 | 5.1 | GO:0006083 | acetate metabolic process(GO:0006083) |
| 0.4 | 5.0 | GO:0015985 | energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986) |
| 0.5 | 4.6 | GO:0070086 | ubiquitin-dependent endocytosis(GO:0070086) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 22.9 | GO:0005739 | mitochondrion(GO:0005739) |
| 0.1 | 11.8 | GO:0005743 | mitochondrial inner membrane(GO:0005743) |
| 0.2 | 9.4 | GO:0005758 | mitochondrial intermembrane space(GO:0005758) |
| 0.1 | 7.8 | GO:0000323 | storage vacuole(GO:0000322) lytic vacuole(GO:0000323) fungal-type vacuole(GO:0000324) |
| 0.8 | 6.1 | GO:0042597 | periplasmic space(GO:0042597) |
| 1.7 | 5.1 | GO:0031422 | RecQ helicase-Topo III complex(GO:0031422) |
| 0.7 | 4.8 | GO:0034657 | GID complex(GO:0034657) |
| 0.9 | 4.5 | GO:0045257 | mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283) |
| 0.4 | 4.4 | GO:0031907 | peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907) |
| 0.3 | 4.2 | GO:0070469 | respiratory chain(GO:0070469) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 10.2 | GO:0001076 | transcription factor activity, RNA polymerase II transcription factor binding(GO:0001076) |
| 1.5 | 7.7 | GO:0015295 | solute:proton symporter activity(GO:0015295) |
| 1.0 | 6.8 | GO:0016833 | oxo-acid-lyase activity(GO:0016833) |
| 2.1 | 6.4 | GO:0004092 | carnitine O-acetyltransferase activity(GO:0004092) carnitine O-acyltransferase activity(GO:0016406) |
| 1.5 | 5.8 | GO:0015193 | L-proline transmembrane transporter activity(GO:0015193) |
| 1.7 | 5.2 | GO:0004108 | citrate (Si)-synthase activity(GO:0004108) citrate synthase activity(GO:0036440) |
| 1.0 | 5.0 | GO:0050308 | sugar-phosphatase activity(GO:0050308) |
| 0.5 | 5.0 | GO:0046933 | proton-transporting ATP synthase activity, rotational mechanism(GO:0046933) |
| 0.8 | 4.8 | GO:0000400 | four-way junction DNA binding(GO:0000400) |
| 0.9 | 4.5 | GO:0008177 | succinate dehydrogenase (ubiquinone) activity(GO:0008177) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 57.4 | PID P53 DOWNSTREAM PATHWAY | Direct p53 effectors |
| 0.5 | 4.9 | PID FANCONI PATHWAY | Fanconi anemia pathway |
| 1.5 | 4.6 | PID HNF3B PATHWAY | FOXA2 and FOXA3 transcription factor networks |
| 0.4 | 1.3 | PID ERBB4 PATHWAY | ErbB4 signaling events |
| 0.4 | 1.1 | PID IL4 2PATHWAY | IL4-mediated signaling events |
| 0.1 | 0.6 | NABA ECM GLYCOPROTEINS | Genes encoding structural ECM glycoproteins |
| 0.1 | 0.4 | PID P38 ALPHA BETA DOWNSTREAM PATHWAY | Signaling mediated by p38-alpha and p38-beta |
| 0.1 | 0.4 | PID P73PATHWAY | p73 transcription factor network |
| 0.1 | 0.3 | SA G1 AND S PHASES | Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition. |
| 0.1 | 0.3 | NABA ECM REGULATORS | Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 57.0 | REACTOME CHONDROITIN SULFATE BIOSYNTHESIS | Genes involved in Chondroitin sulfate biosynthesis |
| 0.7 | 5.9 | REACTOME GLUCONEOGENESIS | Genes involved in Gluconeogenesis |
| 1.0 | 2.9 | REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS | Genes involved in Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. |
| 0.5 | 1.5 | REACTOME PI3K EVENTS IN ERBB2 SIGNALING | Genes involved in PI3K events in ERBB2 signaling |
| 0.3 | 1.4 | REACTOME METABOLISM OF POLYAMINES | Genes involved in Metabolism of polyamines |
| 0.4 | 1.1 | REACTOME MEIOTIC SYNAPSIS | Genes involved in Meiotic Synapsis |
| 0.1 | 1.0 | REACTOME MEIOSIS | Genes involved in Meiosis |
| 0.2 | 0.8 | REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES | Genes involved in Metabolism of amino acids and derivatives |
| 0.2 | 0.7 | REACTOME MITOCHONDRIAL PROTEIN IMPORT | Genes involved in Mitochondrial Protein Import |
| 0.2 | 0.7 | REACTOME DOUBLE STRAND BREAK REPAIR | Genes involved in Double-Strand Break Repair |