Results for YDR026c
Z-value: 2.57
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Transcription factors associated with YDR026c
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
|
NSI1
|
S000002433 | RNA polymerase I termination factor |
Activity-expression correlation:
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| YLR154C Show fit | 29.73 |
Ribonuclease H2 subunit, required for RNase H2 activity |
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| YLR154W-A Show fit | 24.93 |
Dubious open reading frame unlikely to encode a protein; encoded within the the 25S rRNA gene on the opposite strand |
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| YLR154W-B Show fit | 24.74 |
Dubious open reading frame unlikely to encode a protein; encoded within the the 25S rRNA gene on the opposite strand |
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| YGR242W Show fit | 23.39 |
Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified ORF YAP1802/YGR241C |
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| YFR055W Show fit | 22.64 |
Putative cystathionine beta-lyase; involved in copper ion homeostasis and sulfur metabolism; null mutant displays increased levels of spontaneous Rad52p foci; expression induced by nitrogen limitation in a GLN3, GAT1-dependent manner |
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| YCR031C Show fit | 22.09 |
Ribosomal protein 59 of the small subunit, required for ribosome assembly and 20S pre-rRNA processing; mutations confer cryptopleurine resistance; nearly identical to Rps14Bp and similar to E. coli S11 and rat S14 ribosomal proteins |
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| YGR241C Show fit | 20.32 |
Protein involved in clathrin cage assembly; binds Pan1p and clathrin; homologous to Yap1801p, member of the AP180 protein family |
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| YFR056C Show fit | 19.80 |
Dubious open reading frame unlikely to encode a protein based on available experimental and comparative sequence data; partially overlaps the uncharacterized gene YFR055W |
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| YHR094C Show fit | 17.94 |
Low-affinity glucose transporter of the major facilitator superfamily, expression is induced by Hxk2p in the presence of glucose and repressed by Rgt1p when glucose is limiting |
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| YIL118W Show fit | 17.34 |
Non-essential small GTPase of the Rho/Rac subfamily of Ras-like proteins involved in the establishment of cell polarity; GTPase activity positively regulated by the GTPase activating protein (GAP) Rgd1p |
Network of associatons between targets according to the STRING database.
First level regulatory network of YDR026c
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.9 | 97.8 | GO:0002181 | cytoplasmic translation(GO:0002181) |
| 0.5 | 67.6 | GO:0006364 | rRNA processing(GO:0006364) |
| 1.7 | 53.3 | GO:0000027 | ribosomal large subunit assembly(GO:0000027) |
| 2.5 | 40.7 | GO:0000028 | ribosomal small subunit assembly(GO:0000028) |
| 5.6 | 39.4 | GO:0043137 | DNA replication, removal of RNA primer(GO:0043137) |
| 1.3 | 33.6 | GO:0006418 | tRNA aminoacylation for protein translation(GO:0006418) |
| 1.9 | 31.1 | GO:0006407 | rRNA export from nucleus(GO:0006407) rRNA transport(GO:0051029) |
| 1.8 | 29.5 | GO:0006415 | translational termination(GO:0006415) |
| 1.1 | 28.8 | GO:0000184 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184) |
| 1.4 | 23.1 | GO:0006450 | regulation of translational fidelity(GO:0006450) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.7 | 103.6 | GO:0022627 | cytosolic small ribosomal subunit(GO:0022627) |
| 1.2 | 98.1 | GO:0022625 | cytosolic large ribosomal subunit(GO:0022625) |
| 0.4 | 58.9 | GO:0005730 | nucleolus(GO:0005730) |
| 0.3 | 43.8 | GO:0005933 | cellular bud(GO:0005933) |
| 0.8 | 40.7 | GO:0030686 | 90S preribosome(GO:0030686) |
| 12.6 | 37.8 | GO:0032299 | ribonuclease H2 complex(GO:0032299) |
| 1.8 | 35.5 | GO:0030118 | clathrin coat(GO:0030118) |
| 0.7 | 29.4 | GO:0044445 | cytosolic part(GO:0044445) |
| 0.6 | 25.3 | GO:0030176 | integral component of endoplasmic reticulum membrane(GO:0030176) |
| 6.2 | 18.7 | GO:0017102 | methionyl glutamyl tRNA synthetase complex(GO:0017102) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.9 | 163.7 | GO:0003735 | structural constituent of ribosome(GO:0003735) |
| 1.2 | 86.5 | GO:0003924 | GTPase activity(GO:0003924) |
| 1.1 | 49.2 | GO:0019843 | rRNA binding(GO:0019843) |
| 9.4 | 37.8 | GO:0004523 | RNA-DNA hybrid ribonuclease activity(GO:0004523) |
| 3.0 | 35.6 | GO:0030276 | clathrin binding(GO:0030276) |
| 1.3 | 33.6 | GO:0016875 | aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876) |
| 1.1 | 32.9 | GO:0004004 | ATP-dependent RNA helicase activity(GO:0004004) |
| 1.6 | 21.3 | GO:0051537 | 2 iron, 2 sulfur cluster binding(GO:0051537) |
| 1.5 | 20.1 | GO:0051015 | actin filament binding(GO:0051015) |
| 3.1 | 18.6 | GO:0016846 | carbon-sulfur lyase activity(GO:0016846) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 2.7 | 8.1 | PID SHP2 PATHWAY | SHP2 signaling |
| 1.6 | 6.6 | PID E2F PATHWAY | E2F transcription factor network |
| 1.6 | 4.8 | PID LKB1 PATHWAY | LKB1 signaling events |
| 1.2 | 3.6 | PID P38 ALPHA BETA DOWNSTREAM PATHWAY | Signaling mediated by p38-alpha and p38-beta |
| 1.2 | 3.5 | PID ERBB2 ERBB3 PATHWAY | ErbB2/ErbB3 signaling events |
| 0.9 | 3.4 | PID UPA UPAR PATHWAY | Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling |
| 0.5 | 2.5 | PID PLK1 PATHWAY | PLK1 signaling events |
| 0.5 | 2.3 | NABA SECRETED FACTORS | Genes encoding secreted soluble factors |
| 0.7 | 2.2 | SA G1 AND S PHASES | Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition. |
| 0.6 | 1.2 | SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES | Genes related to the insulin receptor pathway |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 2.2 | 17.9 | REACTOME ACTIVATION OF THE MRNA UPON BINDING OF THE CAP BINDING COMPLEX AND EIFS AND SUBSEQUENT BINDING TO 43S | Genes involved in Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S |
| 1.0 | 15.5 | REACTOME METABOLISM OF MRNA | Genes involved in Metabolism of mRNA |
| 2.0 | 13.8 | REACTOME DEADENYLATION DEPENDENT MRNA DECAY | Genes involved in Deadenylation-dependent mRNA decay |
| 3.0 | 9.0 | REACTOME SIGNALLING TO ERKS | Genes involved in Signalling to ERKs |
| 1.1 | 7.9 | REACTOME EXTENSION OF TELOMERES | Genes involved in Extension of Telomeres |
| 2.4 | 7.1 | REACTOME SLC MEDIATED TRANSMEMBRANE TRANSPORT | Genes involved in SLC-mediated transmembrane transport |
| 0.8 | 5.8 | REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS | Genes involved in Association of TriC/CCT with target proteins during biosynthesis |
| 1.9 | 5.7 | REACTOME SIGNALING BY RHO GTPASES | Genes involved in Signaling by Rho GTPases |
| 2.7 | 5.5 | REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS | Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements |
| 2.5 | 5.0 | REACTOME G1 PHASE | Genes involved in G1 Phase |