Results for YAP7
Z-value: 1.46
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Transcription factors associated with YAP7
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
|
YAP7
|
S000005388 | Putative basic leucine zipper (bZIP) transcription factor |
Activity-expression correlation:
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| YPL171C Show fit | 16.81 |
Widely conserved NADPH oxidoreductase containing flavin mononucleotide (FMN), homologous to Oye2p with slight differences in ligand binding and catalytic properties; may be involved in sterol metabolism |
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| YDR343C Show fit | 11.97 |
High-affinity glucose transporter of the major facilitator superfamily, nearly identical to Hxt7p, expressed at high basal levels relative to other HXTs, repression of expression by high glucose requires SNF3 |
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| YLR307C-A Show fit | 9.57 |
Putative protein of unknown function |
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| YCR021C Show fit | 9.20 |
Hydrophobic plasma membrane localized, stress-responsive protein that negatively regulates the H(+)-ATPase Pma1p; induced by heat shock, ethanol treatment, weak organic acid, glucose limitation, and entry into stationary phase |
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| YDR453C Show fit | 8.53 |
Stress inducible cytoplasmic thioredoxin peroxidase; cooperates with Tsa1p in the removal of reactive oxygen, nitrogen and sulfur species using thioredoxin as hydrogen donor; deletion enhances the mutator phenotype of tsa1 mutants |
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| YDR277C Show fit | 7.89 |
Negative regulator of the glucose-sensing signal transduction pathway, required for repression of transcription by Rgt1p; interacts with Rgt1p and the Snf3p and Rgt2p glucose sensors; phosphorylated by Yck1p, triggering Mth1p degradation |
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| YFL030W Show fit | 7.75 |
Alanine:glyoxylate aminotransferase (AGT), catalyzes the synthesis of glycine from glyoxylate, which is one of three pathways for glycine biosynthesis in yeast; has similarity to mammalian and plant alanine:glyoxylate aminotransferases |
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| YHL040C Show fit | 7.74 |
Transporter, member of the ARN family of transporters that specifically recognize siderophore-iron chelates; responsible for uptake of iron bound to ferrirubin, ferrirhodin, and related siderophores |
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| YNR034W-A Show fit | 7.54 |
Putative protein of unknown function; expression is regulated by Msn2p/Msn4p |
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| YER065C Show fit | 6.69 |
Isocitrate lyase, catalyzes the formation of succinate and glyoxylate from isocitrate, a key reaction of the glyoxylate cycle; expression of ICL1 is induced by growth on ethanol and repressed by growth on glucose |
Network of associatons between targets according to the STRING database.
First level regulatory network of YAP7
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.9 | 21.5 | GO:0008645 | hexose transport(GO:0008645) monosaccharide transport(GO:0015749) |
| 1.2 | 9.8 | GO:0015891 | siderophore transport(GO:0015891) |
| 3.1 | 9.2 | GO:0032780 | negative regulation of ATPase activity(GO:0032780) |
| 1.0 | 8.4 | GO:0008615 | pyridoxine metabolic process(GO:0008614) pyridoxine biosynthetic process(GO:0008615) vitamin B6 metabolic process(GO:0042816) vitamin B6 biosynthetic process(GO:0042819) |
| 0.6 | 8.4 | GO:0015986 | energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986) |
| 2.6 | 7.8 | GO:0006545 | glycine biosynthetic process(GO:0006545) |
| 0.2 | 7.5 | GO:0071940 | ascospore wall assembly(GO:0030476) spore wall assembly(GO:0042244) spore wall biogenesis(GO:0070590) ascospore wall biogenesis(GO:0070591) fungal-type cell wall assembly(GO:0071940) |
| 0.3 | 7.4 | GO:0006915 | apoptotic process(GO:0006915) cell death(GO:0008219) programmed cell death(GO:0012501) |
| 0.8 | 7.2 | GO:0006097 | glyoxylate cycle(GO:0006097) |
| 0.6 | 7.1 | GO:0006526 | arginine biosynthetic process(GO:0006526) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 20.5 | GO:0016021 | integral component of membrane(GO:0016021) |
| 0.3 | 12.6 | GO:0031225 | anchored component of membrane(GO:0031225) |
| 0.3 | 8.6 | GO:0070469 | respiratory chain(GO:0070469) |
| 0.1 | 7.4 | GO:0044440 | endosome membrane(GO:0010008) endosomal part(GO:0044440) |
| 0.1 | 6.5 | GO:0000322 | storage vacuole(GO:0000322) lytic vacuole(GO:0000323) fungal-type vacuole(GO:0000324) |
| 0.0 | 5.7 | GO:0005743 | mitochondrial inner membrane(GO:0005743) |
| 1.8 | 5.4 | GO:0045265 | mitochondrial proton-transporting ATP synthase, stator stalk(GO:0000274) proton-transporting ATP synthase, stator stalk(GO:0045265) |
| 0.4 | 5.0 | GO:0005619 | ascospore wall(GO:0005619) |
| 0.7 | 4.4 | GO:0033263 | CORVET complex(GO:0033263) |
| 0.1 | 3.8 | GO:0042579 | peroxisome(GO:0005777) microbody(GO:0042579) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 3.5 | 14.0 | GO:0016661 | oxidoreductase activity, acting on other nitrogenous compounds as donors(GO:0016661) |
| 0.9 | 12.8 | GO:0005353 | fructose transmembrane transporter activity(GO:0005353) mannose transmembrane transporter activity(GO:0015578) |
| 0.2 | 10.0 | GO:0001228 | transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077) transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228) |
| 2.4 | 9.7 | GO:0015343 | siderophore transmembrane transporter activity(GO:0015343) iron chelate transmembrane transporter activity(GO:0015603) siderophore transporter activity(GO:0042927) |
| 0.3 | 8.5 | GO:0016811 | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides(GO:0016811) |
| 0.8 | 8.4 | GO:0046933 | proton-transporting ATP synthase activity, rotational mechanism(GO:0046933) |
| 0.4 | 6.8 | GO:0016769 | transaminase activity(GO:0008483) transferase activity, transferring nitrogenous groups(GO:0016769) |
| 0.2 | 6.7 | GO:0008234 | cysteine-type peptidase activity(GO:0008234) |
| 2.2 | 6.5 | GO:0016406 | carnitine O-acetyltransferase activity(GO:0004092) carnitine O-acyltransferase activity(GO:0016406) |
| 2.2 | 6.5 | GO:0004088 | carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity(GO:0004088) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 82.1 | PID CD8 TCR DOWNSTREAM PATHWAY | Downstream signaling in naïve CD8+ T cells |
| 2.3 | 7.0 | PID IL4 2PATHWAY | IL4-mediated signaling events |
| 0.8 | 2.5 | PID FOXO PATHWAY | FoxO family signaling |
| 0.7 | 2.2 | PID AR PATHWAY | Coregulation of Androgen receptor activity |
| 0.3 | 1.4 | PID CXCR4 PATHWAY | CXCR4-mediated signaling events |
| 0.4 | 1.2 | PID AP1 PATHWAY | AP-1 transcription factor network |
| 0.2 | 0.7 | PID CMYB PATHWAY | C-MYB transcription factor network |
| 0.4 | 0.4 | PID TCR PATHWAY | TCR signaling in naïve CD4+ T cells |
| 0.1 | 0.3 | PID ERBB2 ERBB3 PATHWAY | ErbB2/ErbB3 signaling events |
| 0.1 | 0.3 | SA G1 AND S PHASES | Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition. |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 82.1 | REACTOME CHONDROITIN SULFATE BIOSYNTHESIS | Genes involved in Chondroitin sulfate biosynthesis |
| 1.4 | 4.1 | REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS | Genes involved in Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. |
| 0.2 | 2.1 | REACTOME DNA REPAIR | Genes involved in DNA Repair |
| 0.6 | 1.8 | REACTOME MEIOTIC SYNAPSIS | Genes involved in Meiotic Synapsis |
| 0.2 | 1.8 | REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES | Genes involved in Metabolism of amino acids and derivatives |
| 0.5 | 1.6 | REACTOME SHC1 EVENTS IN ERBB4 SIGNALING | Genes involved in SHC1 events in ERBB4 signaling |
| 0.1 | 0.6 | REACTOME DIABETES PATHWAYS | Genes involved in Diabetes pathways |
| 0.1 | 0.3 | REACTOME APOPTOTIC EXECUTION PHASE | Genes involved in Apoptotic execution phase |