Results for YAP6
Z-value: 0.59
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Transcription factors associated with YAP6
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
|
YAP6
|
S000002667 | Basic leucine zipper (bZIP) transcription factor |
Activity-expression correlation:
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| YKL217W Show fit | 1.82 |
Lactate transporter, required for uptake of lactate and pyruvate; phosphorylated; expression is derepressed by transcriptional activator Cat8p during respiratory growth, and repressed in the presence of glucose, fructose, and mannose |
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| YDL210W Show fit | 1.28 |
Permease that serves as a gamma-aminobutyrate (GABA) transport protein involved in the utilization of GABA as a nitrogen source; catalyzes the transport of putrescine and delta-aminolevulinic acid (ALA); localized to the vacuolar membrane |
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| YNR034W-A Show fit | 1.26 |
Putative protein of unknown function; expression is regulated by Msn2p/Msn4p |
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| YML131W Show fit | 1.25 |
Putative protein of unknown function with similarity to oxidoreductases; HOG1 and SKO1-dependent mRNA expression is induced after osmotic shock; GFP-fusion protein localizes to the cytoplasm and is induced by the DNA-damaging agent MMS |
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| YAL062W Show fit | 1.22 |
NADP(+)-dependent glutamate dehydrogenase, synthesizes glutamate from ammonia and alpha-ketoglutarate; rate of alpha-ketoglutarate utilization differs from Gdh1p; expression regulated by nitrogen and carbon sources |
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| YGL258W-A Show fit | 1.15 |
Putative protein of unknown function |
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| YKL044W Show fit | 1.10 |
Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data |
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| YDR342C Show fit | 1.07 |
High-affinity glucose transporter of the major facilitator superfamily, nearly identical to Hxt6p, expressed at high basal levels relative to other HXTs, expression repressed by high glucose levels |
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| YMR107W Show fit | 1.06 |
Protein required for survival at high temperature during stationary phase; not required for growth on nonfermentable carbon sources |
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| YLR327C Show fit | 1.00 |
Protein of unknown function that associates with ribosomes |
Network of associatons between targets according to the STRING database.
First level regulatory network of YAP6
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.5 | 1.9 | GO:0006848 | pyruvate transport(GO:0006848) |
| 0.1 | 1.7 | GO:0005978 | glycogen biosynthetic process(GO:0005978) |
| 0.3 | 1.3 | GO:0015847 | putrescine transport(GO:0015847) |
| 0.2 | 1.2 | GO:0005980 | glycogen catabolic process(GO:0005980) |
| 0.1 | 1.1 | GO:0015891 | siderophore transport(GO:0015891) |
| 0.1 | 1.1 | GO:0033617 | mitochondrial respiratory chain complex IV assembly(GO:0033617) |
| 0.1 | 0.9 | GO:0000128 | flocculation(GO:0000128) flocculation via cell wall protein-carbohydrate interaction(GO:0000501) |
| 0.0 | 0.9 | GO:0009060 | aerobic respiration(GO:0009060) |
| 0.3 | 0.8 | GO:0015755 | fructose transport(GO:0015755) |
| 0.1 | 0.8 | GO:0006829 | zinc II ion transport(GO:0006829) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 4.0 | GO:0000324 | storage vacuole(GO:0000322) lytic vacuole(GO:0000323) fungal-type vacuole(GO:0000324) |
| 0.0 | 2.8 | GO:0005743 | mitochondrial inner membrane(GO:0005743) |
| 0.0 | 2.1 | GO:0031225 | anchored component of membrane(GO:0031225) |
| 0.0 | 0.8 | GO:0005758 | mitochondrial intermembrane space(GO:0005758) |
| 0.1 | 0.7 | GO:0045273 | mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283) |
| 0.1 | 0.7 | GO:0045277 | mitochondrial respiratory chain complex IV(GO:0005751) respiratory chain complex IV(GO:0045277) |
| 0.1 | 0.6 | GO:0000164 | protein phosphatase type 1 complex(GO:0000164) |
| 0.0 | 0.6 | GO:0031226 | integral component of plasma membrane(GO:0005887) intrinsic component of plasma membrane(GO:0031226) |
| 0.0 | 0.6 | GO:0009295 | nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645) |
| 0.0 | 0.5 | GO:0005769 | early endosome(GO:0005769) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.7 | 3.6 | GO:0015295 | solute:proton symporter activity(GO:0015295) |
| 0.0 | 1.3 | GO:0001228 | transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077) transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228) |
| 0.3 | 1.1 | GO:0005537 | mannose binding(GO:0005537) |
| 0.2 | 0.9 | GO:0015146 | pentose transmembrane transporter activity(GO:0015146) |
| 0.1 | 0.9 | GO:0031072 | heat shock protein binding(GO:0031072) |
| 0.3 | 0.8 | GO:0016289 | CoA hydrolase activity(GO:0016289) |
| 0.2 | 0.8 | GO:0004396 | hexokinase activity(GO:0004396) |
| 0.2 | 0.8 | GO:0050308 | sugar-phosphatase activity(GO:0050308) |
| 0.1 | 0.8 | GO:0005385 | zinc ion transmembrane transporter activity(GO:0005385) |
| 0.1 | 0.8 | GO:0022838 | substrate-specific channel activity(GO:0022838) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 22.9 | PID LIS1 PATHWAY | Lissencephaly gene (LIS1) in neuronal migration and development |
| 0.2 | 0.7 | PID IL4 2PATHWAY | IL4-mediated signaling events |
| 0.1 | 0.3 | PID P38 ALPHA BETA DOWNSTREAM PATHWAY | Signaling mediated by p38-alpha and p38-beta |
| 0.1 | 0.3 | PID AR PATHWAY | Coregulation of Androgen receptor activity |
| 0.1 | 0.2 | PID EPHA2 FWD PATHWAY | EPHA2 forward signaling |
| 0.1 | 0.2 | PID ERBB2 ERBB3 PATHWAY | ErbB2/ErbB3 signaling events |
| 0.0 | 0.1 | PID CXCR4 PATHWAY | CXCR4-mediated signaling events |
| 0.0 | 0.1 | PID P73PATHWAY | p73 transcription factor network |
| 0.0 | 0.0 | PID INTEGRIN A4B1 PATHWAY | Alpha4 beta1 integrin signaling events |
| 0.0 | 0.0 | NABA ECM GLYCOPROTEINS | Genes encoding structural ECM glycoproteins |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 22.9 | REACTOME CHONDROITIN SULFATE BIOSYNTHESIS | Genes involved in Chondroitin sulfate biosynthesis |
| 0.1 | 0.6 | REACTOME GLUCONEOGENESIS | Genes involved in Gluconeogenesis |
| 0.0 | 0.4 | REACTOME DNA REPAIR | Genes involved in DNA Repair |
| 0.1 | 0.3 | REACTOME ACTIVATED TLR4 SIGNALLING | Genes involved in Activated TLR4 signalling |
| 0.0 | 0.3 | REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES | Genes involved in Metabolism of amino acids and derivatives |
| 0.1 | 0.2 | REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING | Genes involved in Downregulation of ERBB2:ERBB3 signaling |
| 0.0 | 0.1 | REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING | Genes involved in Negative regulators of RIG-I/MDA5 signaling |
| 0.0 | 0.1 | REACTOME MEIOTIC RECOMBINATION | Genes involved in Meiotic Recombination |