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Results for YAP3

Z-value: 0.69

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Transcription factors associated with YAP3

Gene Symbol Gene ID Gene Info
YAP3
S000001001 Basic leucine zipper (bZIP) transcription factor

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
YAP3YHL009C0.203.3e-01Click!

Activity profile of YAP3 motif

Sorted Z-values of YAP3 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
YAR053W 3.08 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data
YAR060C 2.54 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data
YHR212W-A 2.53 Putative protein of unknown function; identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching
YPL223C 2.03
GRE1
Hydrophilin of unknown function; stress induced (osmotic, ionic, oxidative, heat shock and heavy metals); regulated by the HOG pathway
YLR307C-A 2.02 Putative protein of unknown function
YHR212C 2.01 Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data
YHR095W 1.92 Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data
YAL062W 1.90
GDH3
NADP(+)-dependent glutamate dehydrogenase, synthesizes glutamate from ammonia and alpha-ketoglutarate; rate of alpha-ketoglutarate utilization differs from Gdh1p; expression regulated by nitrogen and carbon sources
YMR175W 1.59
SIP18
Protein of unknown function whose expression is induced by osmotic stress
YKR039W 1.42
GAP1
General amino acid permease; localization to the plasma membrane is regulated by nitrogen source
YDR043C 1.38
NRG1
Transcriptional repressor that recruits the Cyc8p-Tup1p complex to promoters; mediates glucose repression and negatively regulates a variety of processes including filamentous growth and alkaline pH response
YMR107W 1.29
SPG4
Protein required for survival at high temperature during stationary phase; not required for growth on nonfermentable carbon sources
YLR327C 1.25
TMA10
Protein of unknown function that associates with ribosomes
YOR178C 1.23
GAC1
Regulatory subunit for Glc7p type-1 protein phosphatase (PP1), tethers Glc7p to Gsy2p glycogen synthase, binds Hsf1p heat shock transcription factor, required for induction of some HSF-regulated genes under heat shock
YNL274C 1.08
GOR1
Glyoxylate reductase; null mutation results in increased biomass after diauxic shift; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies
YAR050W 1.07
FLO1
Lectin-like protein involved in flocculation, cell wall protein that binds to mannose chains on the surface of other cells, confers floc-forming ability that is chymotrypsin sensitive and heat resistant; similar to Flo5p
YML128C 0.96
MSC1
Protein of unknown function; mutant is defective in directing meiotic recombination events to homologous chromatids; the authentic, non-tagged protein is detected in highly purified mitochondria and is phosphorylated
YAL063C 0.94
FLO9
Lectin-like protein with similarity to Flo1p, thought to be expressed and involved in flocculation
YAL067W-A 0.94 Putative protein of unknown function; identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching
YFR057W 0.94 Putative protein of unknown function
YPL119C 0.93
DBP1
Putative ATP-dependent RNA helicase of the DEAD-box protein family; mutants show reduced stability of the 40S ribosomal subunit scanning through 5' untranslated regions of mRNAs
YMR206W 0.93 Putative protein of unknown function; YMR206W is not an essential gene
YER101C 0.93
AST2
Protein that may have a role in targeting of plasma membrane [H+]ATPase (Pma1p) to the plasma membrane, as suggested by analysis of genetic interactions
YAR047C 0.90 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data
YAR035W 0.90
YAT1
Outer mitochondrial carnitine acetyltransferase, minor ethanol-inducible enzyme involved in transport of activated acyl groups from the cytoplasm into the mitochondrial matrix; phosphorylated
YKR040C 0.88 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the uncharacterized ORF YKR041W
YIL057C 0.85 Putative protein of unknown function; expression induced under carbon limitation and repressed under high glucose
YNL036W 0.85
NCE103
Carbonic anhydrase; poorly transcribed under aerobic conditions and at an undetectable level under anaerobic conditions; involved in non-classical protein export pathway
YMR090W 0.84 Putative protein of unknown function with similarity to DTDP-glucose 4,6-dehydratases; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; YMR090W is not an essential gene
YMR164C 0.82
MSS11
Transcription factor involved in regulation of invasive growth and starch degradation; controls the activation of MUC1 and STA2 in response to nutritional signals
YDL022W 0.81
GPD1
NAD-dependent glycerol-3-phosphate dehydrogenase, key enzyme of glycerol synthesis, essential for growth under osmotic stress; expression regulated by high-osmolarity glycerol response pathway; homolog of Gpd2p
YDL023C 0.79 Dubious open reading frame, unlikely to encode a protein; not conserved in other Saccharomyces species; overlaps the verified gene GPD1; deletion confers sensitivity to GSAO; deletion in cyr1 mutant results in loss of stress resistance
YGR087C 0.77
PDC6
Minor isoform of pyruvate decarboxylase, decarboxylates pyruvate to acetaldehyde, involved in amino acid catabolism; transcription is glucose- and ethanol-dependent, and is strongly induced during sulfur limitation
YJL116C 0.77
NCA3
Protein that functions with Nca2p to regulate mitochondrial expression of subunits 6 (Atp6p) and 8 (Atp8p ) of the Fo-F1 ATP synthase; member of the SUN family
YLR366W 0.74 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the dubious ORF YLR364C-A
YKL044W 0.73 Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data
YHL040C 0.72
ARN1
Transporter, member of the ARN family of transporters that specifically recognize siderophore-iron chelates; responsible for uptake of iron bound to ferrirubin, ferrirhodin, and related siderophores
YLR270W 0.72
DCS1
Non-essential hydrolase involved in mRNA decapping, may function in a feedback mechanism to regulate deadenylation, contains pyrophosphatase activity and a HIT (histidine triad) motif; interacts with neutral trehalase Nth1p
YDR374C 0.72 Putative protein of unknown function
YMR013C 0.71
SEC59
Dolichol kinase, catalyzes the terminal step in dolichyl monophosphate (Dol-P) biosynthesis; required for viability and for normal rates of lipid intermediate synthesis and protein N-glycosylation
YNL194C 0.70 Integral membrane protein localized to eisosomes; sporulation and plasma membrane sphingolipid content are altered in mutants; has homologs SUR7 and FMP45; GFP-fusion protein is induced in response to the DNA-damaging agent MMS
YBR071W 0.69 Putative protein of unknown function; (GFP)-fusion and epitope-tagged proteins localize to the cytoplasm; mRNA expression may be regulated by the cell cycle and/or cell wall stress
YMR174C 0.68
PAI3
Cytoplasmic proteinase A (Pep4p) inhibitor, dependent on Pbs2p and Hog1p protein kinases for osmotic induction; intrinsically unstructured, N-terminal half becomes ordered in the active site of proteinase A upon contact
YJL057C 0.67
IKS1
Putative serine/threonine kinase; expression is induced during mild heat stress; deletion mutants are hypersensitive to copper sulphate and resistant to sorbate; interacts with an N-terminal fragment of Sst2p
YJR137C 0.67
ECM17
Sulfite reductase beta subunit, involved in amino acid biosynthesis, transcription repressed by methionine
YOL151W 0.67
GRE2
3-methylbutanal reductase and NADPH-dependent methylglyoxal reductase (D-lactaldehyde dehydrogenase); stress induced (osmotic, ionic, oxidative, heat shock and heavy metals); regulated by the HOG pathway
YPR005C 0.66
HAL1
Cytoplasmic protein involved in halotolerance; decreases intracellular Na+ (via Ena1p) and increases intracellular K+ by decreasing efflux; expression repressed by Ssn6p-Tup1p and Sko1p and induced by NaCl, KCl, and sorbitol through Gcn4p
YPR007C 0.66
REC8
Meiosis-specific component of sister chromatid cohesion complex; maintains cohesion between sister chromatids during meiosis I; maintains cohesion between centromeres of sister chromatids until meiosis II; homolog of S. pombe Rec8p
YNL142W 0.65
MEP2
Ammonium permease involved in regulation of pseudohyphal growth; belongs to a ubiquitous family of cytoplasmic membrane proteins that transport only ammonium (NH4+); expression is under the nitrogen catabolite repression regulation
YOL126C 0.65
MDH2
Cytoplasmic malate dehydrogenase, one of three isozymes that catalyze interconversion of malate and oxaloacetate; involved in the glyoxylate cycle and gluconeogenesis during growth on two-carbon compounds; interacts with Pck1p and Fbp1
YEL007W 0.64 Putative protein with sequence similarity to S. pombe gti1+ (gluconate transport inducer 1)
YLR365W 0.64 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps dubious gene YLR364C-A; YLR365W is not an essential gene
YOR192C-C 0.63 Putative protein of unknown function; identified by expression profiling and mass spectrometry
YJR138W 0.62
IML1
Protein of unknown function, green fluorescent protein (GFP)-fusion protein localizes to the vacuolar membrane
YBR182C 0.61
SMP1
Putative transcription factor involved in regulating the response to osmotic stress; member of the MADS-box family of transcription factors
YAR019W-A 0.61 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data
YMR081C 0.61
ISF1
Serine-rich, hydrophilic protein with similarity to Mbr1p; overexpression suppresses growth defects of hap2, hap3, and hap4 mutants; expression is under glucose control; cotranscribed with NAM7 in a cyp1 mutant
YKL223W 0.60 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data
YPL222W 0.59
FMP40
Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies
YLR004C 0.59
THI73
Putative plasma membrane permease proposed to be involved in carboxylic acid uptake and repressed by thiamine; substrate of Dbf2p/Mob1p kinase; transcription is altered if mitochondrial dysfunction occurs
YNR002C 0.58
ATO2
Putative transmembrane protein involved in export of ammonia, a starvation signal that promotes cell death in aging colonies; phosphorylated in mitochondria; member of the TC 9.B.33 YaaH family; homolog of Ady2p and Y. lipolytica Gpr1p
YOR394W 0.57
PAU21
Hypothetical protein
YBR076C-A 0.57 Dubious open reading frame unlikely to encode a protein; partially overlaps verified gene ECM8; identified by fungal homology and RT-PCR
YHR075C 0.56
PPE1
Protein with carboxyl methyl esterase activity that may have a role in demethylation of the phosphoprotein phosphatase catalytic subunit; also identified as a small subunit mitochondrial ribosomal protein
YMR273C 0.56
ZDS1
Protein that interacts with silencing proteins at the telomere, involved in transcriptional silencing; has a role in localization of Bcy1p, a regulatory subunit of protein kinase A; implicated in mRNA nuclear export
YKL224C 0.56
PAU16
Putative protein of unknown function
YLL023C 0.55 Protein of unknown function; highly conserved across species and orthologous to human TMEM33; may interact with ribosomes, based on co-purification experiments; GFP-fusion protein localizes to the endoplasmic reticulum
YHL041W 0.55 Dubious open reading frame unlikely to encode a protein, based on experimental and comparative sequence data
YFR053C 0.55
HXK1
Hexokinase isoenzyme 1, a cytosolic protein that catalyzes phosphorylation of glucose during glucose metabolism; expression is highest during growth on non-glucose carbon sources; glucose-induced repression involves the hexokinase Hxk2p
YNL143C 0.54 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data
YOR268C 0.53 Putative protein of unknown function; sporulation is abnormal in homozygous diploid; YOR268C is not an essential gene
YOR062C 0.53 Protein of unknown function; similar to YKR075Cp and Reg1p; expression regulated by glucose and Rgt1p; GFP-fusion protein is induced in response to the DNA-damaging agent MMS
YGR144W 0.53
THI4
Thiazole synthase, catalyzes formation of the thiazole moiety of thiamin pyrophosphate; required for thiamine biosynthesis and for mitochondrial genome stability
YDR069C 0.52
DOA4
Ubiquitin isopeptidase, required for recycling ubiquitin from proteasome-bound ubiquitinated intermediates, acts at the late endosome/prevacuolar compartment to recover ubiquitin from ubiquitinated membrane proteins en route to the vacuole
YMR180C 0.52
CTL1
RNA 5'-triphosphatase, localizes to both the nucleus and cytoplasm
YKL016C 0.52
ATP7
Subunit d of the stator stalk of mitochondrial F1F0 ATP synthase, which is a large, evolutionarily conserved enzyme complex required for ATP synthesis
YER181C 0.52 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative data; extensively overlaps a Ty1 LTR; protein product is detected in highly purified mitochondria in high-throughput studies
YLR122C 0.52 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the dubious ORF YLR123C
YAL061W 0.51
BDH2
Putative medium-chain alcohol dehydrogenase with similarity to BDH1; transcription induced by constitutively active PDR1 and PDR3; BDH2 is an essential gene
YAR023C 0.51 Putative integral membrane protein, member of DUP240 gene family
YIR041W 0.50
PAU15
Hypothetical protein
YKL161C 0.50 Protein kinase implicated in the Slt2p mitogen-activated (MAP) kinase signaling pathway; associates with Rlm1p
YPL062W 0.50 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; YPL062W is not an essential gene; homozygous diploid mutant shows a decrease in glycogen accumulation
YMR105C 0.49
PGM2
Phosphoglucomutase, catalyzes the conversion from glucose-1-phosphate to glucose-6-phosphate, which is a key step in hexose metabolism; functions as the acceptor for a Glc-phosphotransferase
YCR068W 0.49
ATG15
Lipase, required for intravacuolar lysis of autophagosomes; located in the endoplasmic reticulum membrane and targeted to intravacuolar vesicles during autophagy via the multivesicular body (MVB) pathway
YLR251W 0.49
SYM1
Protein required for ethanol metabolism; induced by heat shock and localized to the inner mitochondrial membrane; homologous to mammalian peroxisomal membrane protein Mpv17
YNL144C 0.49 Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; YNL144C is not an essential gene
YNR034W-A 0.49 Putative protein of unknown function; expression is regulated by Msn2p/Msn4p
YFR026C 0.48 Putative protein of unknown function
YOR161C 0.47
PNS1
Protein of unknown function; has similarity to Torpedo californica tCTL1p, which is postulated to be a choline transporter, neither null mutation nor overexpression affects choline transport
YAL054C 0.47
ACS1
Acetyl-coA synthetase isoform which, along with Acs2p, is the nuclear source of acetyl-coA for histone acetlyation; expressed during growth on nonfermentable carbon sources and under aerobic conditions
YDL169C 0.47
UGX2
Protein of unknown function, transcript accumulates in response to any combination of stress conditions
YLR356W 0.46 Putative protein of unknown function with similarity to SCM4; green fluorescent protein (GFP)-fusion protein localizes to mitochondria; YLR356W is not an essential gene
YER167W 0.46
BCK2
Protein rich in serine and threonine residues involved in protein kinase C signaling pathway, which controls cell integrity; overproduction suppresses pkc1 mutations
YML012C-A 0.46 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified gene SEL1
YER188W 0.45 Hypothetical protein
YPR192W 0.45
AQY1
Spore-specific water channel that mediates the transport of water across cell membranes, developmentally controlled; may play a role in spore maturation, probably by allowing water outflow, may be involved in freeze tolerance
YEL060C 0.45
PRB1
Vacuolar proteinase B (yscB), a serine protease of the subtilisin family; involved in protein degradation in the vacuole and required for full protein degradation during sporulation
YPR015C 0.45 Putative protein of unknown function
YIL108W 0.45 Putative metalloprotease
YEL008W 0.45 Hypothetical protein predicted to be involved in metabolism
YLL030C 0.45 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data
YHR211W 0.44
FLO5
Lectin-like cell wall protein (flocculin) involved in flocculation, binds to mannose chains on the surface of other cells, confers floc-forming ability that is chymotrypsin resistant but heat labile; similar to Flo1p
YLR123C 0.44 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the dubious ORF YLR122C; contains characteristic aminoacyl-tRNA motif
YPR065W 0.44
ROX1
Heme-dependent repressor of hypoxic genes; contains an HMG domain that is responsible for DNA bending activity
YEL059W 0.44 Dubious open reading frame unlikely to encode a functional protein
YGL262W 0.44 Putative protein of unknown function; null mutant displays elevated sensitivity to expression of a mutant huntingtin fragment or of alpha-synuclein; YGL262W is not an essential gene
YBR169C 0.43
SSE2
Member of the heat shock protein 70 (HSP70) family; may be involved in protein folding; localized to the cytoplasm; highly homologous to the heat shock protein Sse1p
YBR147W 0.43
RTC2
Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; null mutant displays fluconazole resistance and suppresses cdc13-1 temperature sensitivity
YFR027W 0.43
ECO1
Acetyltransferase required for the establishment of sister chromatid cohesion during DNA replication and in response to double-strand breaks; also required for postreplicative double-strand break repair
YMR068W 0.43
AVO2
Component of a complex containing the Tor2p kinase and other proteins, which may have a role in regulation of cell growth
YMR169C 0.43
ALD3
Cytoplasmic aldehyde dehydrogenase, involved in beta-alanine synthesis; uses NAD+ as the preferred coenzyme; very similar to Ald2p; expression is induced by stress and repressed by glucose
YPL080C 0.43 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data
YBL078C 0.42
ATG8
Conserved protein that is a component of autophagosomes and Cvt vesicles; undergoes C-terminal conjugation to phosphatidylethanolamine (PE), Atg8p-PE is anchored to membranes and may mediate membrane fusion during autophagosome formation
YFR016C 0.41 Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and bud; interacts with Spa2p; YFL016C is not an essential gene
YJR159W 0.41
SOR1
Sorbitol dehydrogenase; expression is induced in the presence of sorbitol
YAR019C 0.41
CDC15
Protein kinase of the Mitotic Exit Network that is localized to the spindle pole bodies at late anaphase; promotes mitotic exit by directly switching on the kinase activity of Dbf2p
YBL049W 0.41
MOH1
Protein of unknown function, has homology to kinase Snf7p; not required for growth on nonfermentable carbon sources; essential for viability in stationary phase
YBL064C 0.41
PRX1
Mitochondrial peroxiredoxin (1-Cys Prx) with thioredoxin peroxidase activity, has a role in reduction of hydroperoxides; induced during respiratory growth and under conditions of oxidative stress; phosphorylated
YFL054C 0.40 Putative channel-like protein; similar to Fps1p; mediates passive diffusion of glycerol in the presence of ethanol
YOL164W-A 0.40 Putative protein of unknown function; identified by fungal homology and RT-PCR
YGR149W 0.40 Putative protein of unknown function; predicted to be an integal membrane protein
YIL119C 0.40
RPI1
Putative transcriptional regulator; overexpression suppresses the heat shock sensitivity of wild-type RAS2 overexpression and also suppresses the cell lysis defect of an mpk1 mutation
YBR292C 0.39 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; YBR292C is not an essential gene
YER103W 0.39
SSA4
Heat shock protein that is highly induced upon stress; plays a role in SRP-dependent cotranslational protein-membrane targeting and translocation; member of the HSP70 family; cytoplasmic protein that concentrates in nuclei upon starvation
YML131W 0.39 Putative protein of unknown function with similarity to oxidoreductases; HOG1 and SKO1-dependent mRNA expression is induced after osmotic shock; GFP-fusion protein localizes to the cytoplasm and is induced by the DNA-damaging agent MMS
YDL222C 0.39
FMP45
Integral membrane protein localized to mitochondria (untagged protein) and eisosomes, immobile patches at the cortex associated with endocytosis; sporulation and sphingolipid content are altered in mutants; has homologs SUR7 and YNL194C
YJR095W 0.39
SFC1
Mitochondrial succinate-fumarate transporter, transports succinate into and fumarate out of the mitochondrion; required for ethanol and acetate utilization
YLR352W 0.38 Putative protein of unknown function with similarity to F-box proteins; interacts with Skp1p and Cdc53p; YLR352W is not an essential gene
YDL214C 0.38
PRR2
Serine/threonine protein kinase that inhibits pheromone induced signalling downstream of MAPK, possibly at the level of the Ste12p transcription factor
YLR273C 0.38
PIG1
Putative targeting subunit for the type-1 protein phosphatase Glc7p that tethers it to the Gsy2p glycogen synthase
YHR125W 0.37 Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data
YPR036W-A 0.37 Protein of unknown function; transcription is regulated by Pdr1p
YJL089W 0.37
SIP4
C6 zinc cluster transcriptional activator that binds to the carbon source-responsive element (CSRE) of gluconeogenic genes; involved in the positive regulation of gluconeogenesis; regulated by Snf1p protein kinase; localized to the nucleus
YJL005W 0.36
CYR1
Adenylate cyclase, required for cAMP production and cAMP-dependent protein kinase signaling; the cAMP pathway controls a variety of cellular processes, including metabolism, cell cycle, stress response, stationary phase, and sporulation
YER150W 0.36
SPI1
GPI-anchored cell wall protein involved in weak acid resistance; basal expression requires Msn2p/Msn4p; expression is induced under conditions of stress and during the diauxic shift; similar to Sed1p
YDL085W 0.36
NDE2
Mitochondrial external NADH dehydrogenase, catalyzes the oxidation of cytosolic NADH; Nde1p and Nde2p are involved in providing the cytosolic NADH to the mitochondrial respiratory chain
YAL066W 0.35 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data
YHL027W 0.35
RIM101
Transcriptional repressor involved in response to pH and in cell wall construction; required for alkaline pH-stimulated haploid invasive growth and sporulation; activated by proteolytic processing; similar to A. nidulans PacC
YHR033W 0.35 Putative protein of unknown function; epitope-tagged protein localizes to the cytoplasm
YGR287C 0.35 Protein of unknown function that may interact with ribosomes, based on co-purification experiments; has similarity to alpha-D-glucosidase (maltase); authentic, non-tagged protein detected in purified mitochondria in high-throughput studies
YLR124W 0.34 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data
YAL067C 0.34
SEO1
Putative permease, member of the allantoate transporter subfamily of the major facilitator superfamily; mutation confers resistance to ethionine sulfoxide
YLR296W 0.34 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data
YNL025C 0.34
SSN8
Cyclin-like component of the RNA polymerase II holoenzyme, involved in phosphorylation of the RNA polymerase II C-terminal domain; involved in glucose repression and telomere maintenance
YIL045W 0.34
PIG2
Putative type-1 protein phosphatase targeting subunit that tethers Glc7p type-1 protein phosphatase to Gsy2p glycogen synthase
YDR461C-A 0.34 Putative protein of unknown function
YIR040C 0.34 Dubious open reading frame unlikely to encode a protein, based on experimental and comparative sequence data
YKL107W 0.34 Putative protein of unknown function
YKL124W 0.34
SSH4
Specificity factor required for Rsp5p-dependent ubiquitination and sorting of cargo proteins at the multivesicular body; identified as a high-copy suppressor of a SHR3 deletion, increasing steady-state levels of amino acid permeases
YOR376W 0.34 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; YOR376W is not an essential gene.
YDR540C 0.33
IRC4
Putative protein of unknown function; null mutant displays increased levels of spontaneous Rad52p foci; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus
YGR289C 0.33
MAL11
Inducible high-affinity maltose transporter (alpha-glucoside transporter); encoded in the MAL1 complex locus; member of the 12 transmembrane domain superfamily of sugar transporters; broad substrate specificity that includes maltotriose
YDR077W 0.33
SED1
Major stress-induced structural GPI-cell wall glycoprotein in stationary-phase cells, associates with translating ribosomes, possible role in mitochondrial genome maintenance; ORF contains two distinct variable minisatellites
YFL053W 0.33
DAK2
Dihydroxyacetone kinase, required for detoxification of dihydroxyacetone (DHA); involved in stress adaptation
YJL130C 0.33
URA2
Bifunctional carbamoylphosphate synthetase (CPSase)-aspartate transcarbamylase (ATCase), catalyzes the first two enzymatic steps in the de novo biosynthesis of pyrimidines; both activities are subject to feedback inhibition by UTP
YHR210C 0.33 Putative protein of unknown function; non-essential gene; highly expressed under anaeorbic conditions; sequence similarity to aldose 1-epimerases such as GAL10
YLR121C 0.33
YPS3
Aspartic protease, attached to the plasma membrane via a glycosylphosphatidylinositol (GPI) anchor
YDR141C 0.33
DOP1
Protein of unknown function, essential for viability, involved in establishing cellular polarity and morphogenesis; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies
YPL258C 0.33
THI21
Hydroxymethylpyrimidine phosphate kinase, involved in the last steps in thiamine biosynthesis; member of a gene family with THI20 and THI22; functionally redundant with Thi20p
YLR425W 0.32
TUS1
Guanine nucleotide exchange factor (GEF) that functions to modulate Rho1p activity as part of the cell integrity signaling pathway; multicopy suppressor of tor2 mutation and ypk1 ypk2 double mutation; potential Cdc28p substrate
YGR292W 0.32
MAL12
Maltase (alpha-D-glucosidase), inducible protein involved in maltose catabolism; encoded in the MAL1 complex locus
YDR171W 0.32
HSP42
Small heat shock protein (sHSP) with chaperone activity; forms barrel-shaped oligomers that suppress unfolded protein aggregation; involved in cytoskeleton reorganization after heat shock
YBL067C 0.32
UBP13
Putative ubiquitin carboxyl-terminal hydrolase, ubiquitin-specific protease that cleaves ubiquitin-protein fusions
YFL033C 0.32
RIM15
Glucose-repressible protein kinase involved in signal transduction during cell proliferation in response to nutrients, specifically the establishment of stationary phase; identified as a regulator of IME2; substrate of Pho80p-Pho85p kinase
YCR091W 0.32
KIN82
Putative serine/threonine protein kinase, most similar to cyclic nucleotide-dependent protein kinase subfamily and the protein kinase C subfamily
YNL037C 0.32
IDH1
Subunit of mitochondrial NAD(+)-dependent isocitrate dehydrogenase, which catalyzes the oxidation of isocitrate to alpha-ketoglutarate in the TCA cycle
YCR021C 0.32
HSP30
Hydrophobic plasma membrane localized, stress-responsive protein that negatively regulates the H(+)-ATPase Pma1p; induced by heat shock, ethanol treatment, weak organic acid, glucose limitation, and entry into stationary phase
YKL216W 0.31
URA1
Dihydroorotate dehydrogenase, catalyzes the fourth enzymatic step in the de novo biosynthesis of pyrimidines, converting dihydroorotic acid into orotic acid
YML089C 0.31 Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data; expression induced by calcium shortage
YPL278C 0.31 Putative protein of unknown function; gene expression regulated by copper levels
YGR039W 0.31 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the Autonomously Replicating Sequence ARS722
YKL028W 0.31
TFA1
TFIIE large subunit, involved in recruitment of RNA polymerase II to the promoter, activation of TFIIH, and promoter opening
YOR177C 0.31
MPC54
Component of the meiotic outer plaque, a membrane-organizing center which is assembled on the cytoplasmic face of the spindle pole body during meiosis II and triggers the formation of the prospore membrane; potential Cdc28p substrate
YEL069C 0.30
HXT13
Hexose transporter, induced in the presence of non-fermentable carbon sources, induced by low levels of glucose, repressed by high levels of glucose
YPR202W 0.30 Putative protein of unknown function with similarity to telomere-encoded helicases; YPR202W is not an essential gene; transcript is predicted to be spliced but there is no evidence that it is spliced in vivo
YER187W 0.30 Putative protein of unknown function; induced in respiratory-deficient cells
YGR290W 0.30 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; putative HLH protein; partially overlaps the verified ORF MAL11/YGR289C (a high-affinity maltose transporter)
YCR106W 0.30
RDS1
Zinc cluster transcription factor involved in conferring resistance to cycloheximide
YOR192C 0.30
THI72
Transporter of thiamine or related compound; shares sequence similarity with Thi7p
YPR010C-A 0.29 Putative protein of unknown function; conserved among Saccharomyces sensu stricto species
YOR152C 0.29 Putative protein of unknown function; has no similarity to any known protein; YOR152C is not an essential gene
YLR269C 0.29 Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data
YOR386W 0.29
PHR1
DNA photolyase involved in photoreactivation, repairs pyrimidine dimers in the presence of visible light; induced by DNA damage; regulated by transcriptional repressor Rph1p
YDR222W 0.29 Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern
YGL071W 0.29
AFT1
Transcription factor involved in iron utilization and homeostasis; binds the consensus site PyPuCACCCPu and activates the expression of target genes in response to changes in iron availability
YGL163C 0.29
RAD54
DNA-dependent ATPase, stimulates strand exchange by modifying the topology of double-stranded DNA; involved in the recombinational repair of double-strand breaks in DNA during vegetative growth and meiosis; member of the SWI/SNF family
YCR089W 0.28
FIG2
Cell wall adhesin, expressed specifically during mating; may be involved in maintenance of cell wall integrity during mating
YKL115C 0.28 Dubious open reading frame, unlikely to encode a protein; partially overlaps the verified gene PRR1
YPR064W 0.28 Dubious open reading frame, unlikely to encode a functional protein; based on available experimental and comparative sequence data
YLR456W 0.28 Putative protein of unknown function; null mutant displays increased resistance to antifungal agents gliotoxin, cycloheximide and H2O2
YPR145W 0.28
ASN1
Asparagine synthetase, isozyme of Asn2p; catalyzes the synthesis of L-asparagine from L-aspartate in the asparagine biosynthetic pathway
YHL045W 0.28 Putative protein of unknown function; not an essential gene
YDR374W-A 0.28 Putative protein of unknown function
YOR199W 0.27 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data
YNL273W 0.27
TOF1
Subunit of a replication-pausing checkpoint complex (Tof1p-Mrc1p-Csm3p) that acts at the stalled replication fork to promote sister chromatid cohesion after DNA damage, facilitating gap repair of damaged DNA; interacts with the MCM helicase
YCR066W 0.27
RAD18
Protein involved in postreplication repair; binds single-stranded DNA and has single-stranded DNA dependent ATPase activity; forms heterodimer with Rad6p; contains RING-finger motif
YOL089C 0.27
HAL9
Putative transcription factor containing a zinc finger; overexpression increases salt tolerance through increased expression of the ENA1 (Na+/Li+ extrusion pump) gene while gene disruption decreases both salt tolerance and ENA1 expression
YJL150W 0.27 Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data
YCR007C 0.27 Putative integral membrane protein, member of DUP240 gene family; YCR007C is not an essential gene

Network of associatons between targets according to the STRING database.

First level regulatory network of YAP3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 3.5 GO:0000128 flocculation(GO:0000128) flocculation via cell wall protein-carbohydrate interaction(GO:0000501)
0.5 1.4 GO:1900460 negative regulation of invasive growth in response to glucose limitation by negative regulation of transcription from RNA polymerase II promoter(GO:1900460)
0.4 1.3 GO:0019676 ammonia assimilation cycle(GO:0019676)
0.4 1.5 GO:0009415 response to water(GO:0009415) cellular response to water stimulus(GO:0071462)
0.3 0.9 GO:0009437 amino-acid betaine metabolic process(GO:0006577) carnitine metabolic process(GO:0009437)
0.2 0.7 GO:1902751 positive regulation of G2/M transition of mitotic cell cycle(GO:0010971) positive regulation of cell cycle G2/M phase transition(GO:1902751)
0.2 0.9 GO:0015976 carbon utilization(GO:0015976)
0.2 0.7 GO:0052547 negative regulation of peptidase activity(GO:0010466) regulation of peptidase activity(GO:0052547)
0.2 1.1 GO:0046185 aldehyde catabolic process(GO:0046185)
0.2 0.7 GO:0097201 negative regulation of transcription from RNA polymerase II promoter in response to stress(GO:0097201)
0.2 0.7 GO:0072488 ammonium transmembrane transport(GO:0072488)
0.2 0.8 GO:0006072 glycerol-3-phosphate metabolic process(GO:0006072)
0.2 1.2 GO:0032069 regulation of nuclease activity(GO:0032069)
0.2 0.8 GO:0000949 aromatic amino acid family catabolic process to alcohol via Ehrlich pathway(GO:0000949)
0.2 0.5 GO:0015755 fructose transport(GO:0015755)
0.2 0.5 GO:0036257 multivesicular body organization(GO:0036257)
0.2 0.3 GO:0010446 response to alkaline pH(GO:0010446) cellular response to alkaline pH(GO:0071469)
0.2 3.1 GO:0005978 glycogen biosynthetic process(GO:0005978)
0.1 0.3 GO:0043270 positive regulation of ion transport(GO:0043270)
0.1 0.5 GO:0010993 regulation of ubiquitin homeostasis(GO:0010993)
0.1 0.9 GO:0000023 maltose metabolic process(GO:0000023)
0.1 0.4 GO:0015740 C4-dicarboxylate transport(GO:0015740)
0.1 0.4 GO:0006067 ethanol metabolic process(GO:0006067)
0.1 0.6 GO:0061393 positive regulation of transcription from RNA polymerase II promoter in response to osmotic stress(GO:0061393)
0.1 0.4 GO:0061414 regulation of gluconeogenesis by regulation of transcription from RNA polymerase II promoter(GO:0035947) positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948) regulation of transcription from RNA polymerase II promoter by a nonfermentable carbon source(GO:0061413) positive regulation of transcription from RNA polymerase II promoter by a nonfermentable carbon source(GO:0061414)
0.1 0.4 GO:0019405 alditol catabolic process(GO:0019405) glycerol catabolic process(GO:0019563)
0.1 1.3 GO:0015846 polyamine transport(GO:0015846)
0.1 0.6 GO:0006207 'de novo' pyrimidine nucleobase biosynthetic process(GO:0006207) 'de novo' UMP biosynthetic process(GO:0044205)
0.1 0.4 GO:0001324 age-dependent general metabolic decline involved in chronological cell aging(GO:0001323) age-dependent response to oxidative stress involved in chronological cell aging(GO:0001324)
0.1 0.4 GO:0006598 polyamine catabolic process(GO:0006598)
0.1 0.3 GO:0032780 negative regulation of ATPase activity(GO:0032780)
0.1 0.4 GO:0031135 negative regulation of conjugation(GO:0031135) negative regulation of conjugation with cellular fusion(GO:0031138) negative regulation of multi-organism process(GO:0043901)
0.1 0.4 GO:0006103 2-oxoglutarate metabolic process(GO:0006103)
0.1 0.1 GO:1900544 positive regulation of nucleotide metabolic process(GO:0045981) positive regulation of purine nucleotide metabolic process(GO:1900544)
0.1 0.3 GO:0015888 thiamine transport(GO:0015888)
0.1 0.6 GO:0090294 nitrogen catabolite activation of transcription from RNA polymerase II promoter(GO:0001080) nitrogen catabolite activation of transcription(GO:0090294)
0.1 0.4 GO:0006171 cAMP biosynthetic process(GO:0006171) cyclic nucleotide biosynthetic process(GO:0009190) cyclic purine nucleotide metabolic process(GO:0052652)
0.1 0.3 GO:0006529 asparagine biosynthetic process(GO:0006529)
0.1 0.3 GO:0006000 fructose metabolic process(GO:0006000)
0.1 0.4 GO:0044746 amino acid transmembrane export from vacuole(GO:0032974) vacuolar transmembrane transport(GO:0034486) vacuolar amino acid transmembrane transport(GO:0034487) amino acid transmembrane export(GO:0044746)
0.1 0.7 GO:0051177 meiotic sister chromatid cohesion(GO:0051177)
0.1 0.3 GO:0006075 (1->3)-beta-D-glucan biosynthetic process(GO:0006075)
0.1 0.3 GO:0042357 thiamine diphosphate biosynthetic process(GO:0009229) thiamine diphosphate metabolic process(GO:0042357)
0.1 0.2 GO:0010039 response to iron ion(GO:0010039) regulation of transcription from RNA polymerase II promoter in response to iron(GO:0034395) cellular response to iron ion(GO:0071281)
0.1 0.2 GO:0042744 hydrogen peroxide metabolic process(GO:0042743) hydrogen peroxide catabolic process(GO:0042744)
0.1 0.2 GO:0045950 negative regulation of mitotic recombination(GO:0045950)
0.1 0.2 GO:0008105 asymmetric protein localization(GO:0008105)
0.1 0.4 GO:1902707 glucose catabolic process(GO:0006007) glycolytic fermentation to ethanol(GO:0019655) glycolytic fermentation(GO:0019660) hexose catabolic process to ethanol(GO:1902707)
0.1 0.9 GO:0009228 thiamine biosynthetic process(GO:0009228) thiamine-containing compound biosynthetic process(GO:0042724)
0.1 0.6 GO:0015891 siderophore transport(GO:0015891)
0.1 0.2 GO:0032874 positive regulation of stress-activated MAPK cascade(GO:0032874) positive regulation of stress-activated protein kinase signaling cascade(GO:0070304)
0.1 0.3 GO:0006102 isocitrate metabolic process(GO:0006102)
0.1 0.2 GO:0043388 positive regulation of DNA binding(GO:0043388) regulation of DNA binding(GO:0051101)
0.1 0.3 GO:0006108 malate metabolic process(GO:0006108)
0.1 1.0 GO:0042026 protein refolding(GO:0042026)
0.1 0.1 GO:0044247 glucan catabolic process(GO:0009251) cellular polysaccharide catabolic process(GO:0044247)
0.1 0.3 GO:0001113 transcriptional open complex formation at RNA polymerase II promoter(GO:0001113)
0.1 0.4 GO:0006083 acetate metabolic process(GO:0006083)
0.1 0.2 GO:0017003 protein-heme linkage(GO:0017003) protein-tetrapyrrole linkage(GO:0017006) cytochrome c-heme linkage(GO:0018063)
0.1 0.4 GO:0070058 tRNA gene clustering(GO:0070058)
0.1 0.3 GO:1904030 negative regulation of cyclin-dependent protein serine/threonine kinase by cyclin degradation(GO:0008054) negative regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045736) negative regulation of cyclin-dependent protein kinase activity(GO:1904030)
0.1 0.5 GO:0007039 protein catabolic process in the vacuole(GO:0007039)
0.1 0.2 GO:0019320 hexose catabolic process(GO:0019320)
0.1 0.2 GO:0033683 nucleotide-excision repair, DNA incision(GO:0033683)
0.1 0.1 GO:0018105 peptidyl-serine phosphorylation(GO:0018105) peptidyl-serine modification(GO:0018209)
0.1 0.8 GO:0015986 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.1 0.8 GO:0009651 response to salt stress(GO:0009651)
0.1 0.2 GO:0000715 nucleotide-excision repair, DNA damage recognition(GO:0000715)
0.1 0.5 GO:0035023 regulation of Rho protein signal transduction(GO:0035023)
0.0 0.2 GO:0006078 (1->6)-beta-D-glucan biosynthetic process(GO:0006078) beta-glucan biosynthetic process(GO:0051274)
0.0 0.4 GO:0006616 SRP-dependent cotranslational protein targeting to membrane, translocation(GO:0006616)
0.0 0.3 GO:0043328 protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328)
0.0 0.3 GO:0051322 anaphase(GO:0051322)
0.0 0.2 GO:0000712 resolution of meiotic recombination intermediates(GO:0000712) meiotic chromosome separation(GO:0051307)
0.0 0.1 GO:0031998 regulation of fatty acid beta-oxidation(GO:0031998) positive regulation of fatty acid beta-oxidation(GO:0032000) regulation of fatty acid oxidation(GO:0046320) positive regulation of fatty acid oxidation(GO:0046321)
0.0 0.2 GO:0070542 response to lipid(GO:0033993) response to oleic acid(GO:0034201) response to fatty acid(GO:0070542) cellular response to lipid(GO:0071396) cellular response to fatty acid(GO:0071398) cellular response to oleic acid(GO:0071400)
0.0 0.3 GO:0009410 response to xenobiotic stimulus(GO:0009410)
0.0 0.4 GO:0046686 response to cadmium ion(GO:0046686)
0.0 0.0 GO:0000706 meiotic DNA double-strand break processing(GO:0000706)
0.0 0.7 GO:0006895 Golgi to endosome transport(GO:0006895)
0.0 0.2 GO:0006848 pyruvate transport(GO:0006848)
0.0 0.3 GO:0045764 positive regulation of cellular amino acid metabolic process(GO:0045764)
0.0 0.3 GO:0048478 replication fork protection(GO:0048478)
0.0 0.1 GO:0046688 response to copper ion(GO:0046688)
0.0 0.1 GO:0045996 negative regulation of transcription by pheromones(GO:0045996) negative regulation of transcription from RNA polymerase II promoter by pheromones(GO:0046020)
0.0 0.2 GO:0000411 regulation of transcription by galactose(GO:0000409) positive regulation of transcription by galactose(GO:0000411)
0.0 0.4 GO:0046685 response to arsenic-containing substance(GO:0046685)
0.0 0.3 GO:0006641 neutral lipid metabolic process(GO:0006638) acylglycerol metabolic process(GO:0006639) triglyceride metabolic process(GO:0006641)
0.0 0.2 GO:0060237 regulation of fungal-type cell wall organization(GO:0060237)
0.0 0.2 GO:0070814 hydrogen sulfide metabolic process(GO:0070813) hydrogen sulfide biosynthetic process(GO:0070814)
0.0 0.1 GO:0060195 antisense RNA transcription(GO:0009300) regulation of antisense RNA transcription(GO:0060194) negative regulation of antisense RNA transcription(GO:0060195)
0.0 0.8 GO:0000422 mitophagy(GO:0000422) mitochondrion disassembly(GO:0061726)
0.0 0.2 GO:0046459 short-chain fatty acid metabolic process(GO:0046459)
0.0 0.2 GO:0071804 cellular potassium ion transport(GO:0071804) potassium ion transmembrane transport(GO:0071805)
0.0 0.3 GO:0070987 error-free translesion synthesis(GO:0070987)
0.0 0.4 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.0 0.1 GO:0006183 GTP biosynthetic process(GO:0006183) GTP metabolic process(GO:0046039)
0.0 0.1 GO:0044783 G1 DNA damage checkpoint(GO:0044783)
0.0 0.3 GO:0022610 cell adhesion(GO:0007155) biological adhesion(GO:0022610)
0.0 0.1 GO:0031573 intra-S DNA damage checkpoint(GO:0031573)
0.0 0.3 GO:0006816 calcium ion transport(GO:0006816)
0.0 0.3 GO:0046777 protein autophosphorylation(GO:0046777)
0.0 0.3 GO:0045332 phospholipid translocation(GO:0045332)
0.0 0.2 GO:0071931 positive regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0071931)
0.0 0.2 GO:0032443 regulation of steroid metabolic process(GO:0019218) regulation of ergosterol biosynthetic process(GO:0032443) regulation of steroid biosynthetic process(GO:0050810)
0.0 0.6 GO:0048278 vesicle docking(GO:0048278)
0.0 0.2 GO:0048209 regulation of COPII vesicle coating(GO:0003400) regulation of vesicle targeting, to, from or within Golgi(GO:0048209) regulation of ER to Golgi vesicle-mediated transport by GTP hydrolysis(GO:0090113)
0.0 0.1 GO:0046323 glucose import(GO:0046323)
0.0 0.1 GO:0042148 strand invasion(GO:0042148)
0.0 0.6 GO:0001558 regulation of cell growth(GO:0001558)
0.0 0.1 GO:0061412 positive regulation of transcription from RNA polymerase II promoter in response to amino acid starvation(GO:0061412)
0.0 0.2 GO:0034965 intronic snoRNA processing(GO:0031070) intronic box C/D snoRNA processing(GO:0034965)
0.0 0.2 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0 0.3 GO:0016925 protein sumoylation(GO:0016925)
0.0 0.2 GO:0015908 fatty acid transport(GO:0015908)
0.0 1.3 GO:0007131 reciprocal meiotic recombination(GO:0007131) reciprocal DNA recombination(GO:0035825)
0.0 0.1 GO:0006482 protein demethylation(GO:0006482) protein dealkylation(GO:0008214) histone demethylation(GO:0016577) demethylation(GO:0070988)
0.0 0.2 GO:0019722 calcium-mediated signaling(GO:0019722)
0.0 0.1 GO:0051058 negative regulation of Ras protein signal transduction(GO:0046580) negative regulation of small GTPase mediated signal transduction(GO:0051058)
0.0 0.6 GO:0007265 Ras protein signal transduction(GO:0007265)
0.0 0.1 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.0 0.1 GO:0030048 actin filament-based movement(GO:0030048) actin filament-based transport(GO:0099515)
0.0 0.1 GO:0015886 heme transport(GO:0015886)
0.0 0.1 GO:0000916 actomyosin contractile ring contraction(GO:0000916) contractile ring contraction(GO:0036213)
0.0 0.0 GO:0051443 positive regulation of ubiquitin-protein transferase activity(GO:0051443)
0.0 0.1 GO:0006545 glycine biosynthetic process(GO:0006545)
0.0 0.1 GO:0032056 positive regulation of translation in response to stress(GO:0032056)
0.0 0.1 GO:0009268 response to pH(GO:0009268)
0.0 0.3 GO:0006312 mitotic recombination(GO:0006312)
0.0 0.1 GO:0009083 branched-chain amino acid catabolic process(GO:0009083)
0.0 0.1 GO:0042868 antisense RNA metabolic process(GO:0042868) antisense RNA transcript catabolic process(GO:0071041)
0.0 0.1 GO:0006741 NADP biosynthetic process(GO:0006741)
0.0 0.2 GO:0031167 rRNA methylation(GO:0031167)
0.0 0.0 GO:0006390 transcription from mitochondrial promoter(GO:0006390)
0.0 0.1 GO:0000266 mitochondrial fission(GO:0000266)
0.0 0.1 GO:0000114 obsolete regulation of transcription involved in G1 phase of mitotic cell cycle(GO:0000114)
0.0 0.1 GO:0045721 negative regulation of cellular carbohydrate metabolic process(GO:0010677) negative regulation of gluconeogenesis(GO:0045721) negative regulation of carbohydrate metabolic process(GO:0045912)
0.0 0.0 GO:0031114 negative regulation of microtubule depolymerization(GO:0007026) regulation of microtubule depolymerization(GO:0031114)
0.0 0.1 GO:0035753 maintenance of DNA trinucleotide repeats(GO:0035753)
0.0 0.3 GO:0030474 spindle pole body duplication(GO:0030474)
0.0 0.1 GO:0042138 meiotic DNA double-strand break formation(GO:0042138)
0.0 0.2 GO:0030242 pexophagy(GO:0030242)
0.0 0.1 GO:0051259 protein oligomerization(GO:0051259)
0.0 0.1 GO:0055088 lipid homeostasis(GO:0055088)
0.0 0.0 GO:0051222 positive regulation of protein transport(GO:0051222) positive regulation of establishment of protein localization(GO:1904951)
0.0 0.0 GO:0000117 regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117)
0.0 0.1 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
0.0 0.2 GO:0006031 aminoglycan biosynthetic process(GO:0006023) chitin biosynthetic process(GO:0006031) glucosamine-containing compound biosynthetic process(GO:1901073)
0.0 0.2 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0 0.2 GO:0007121 bipolar cellular bud site selection(GO:0007121)
0.0 0.7 GO:0009060 aerobic respiration(GO:0009060)
0.0 0.2 GO:0046854 lipid phosphorylation(GO:0046834) phosphatidylinositol phosphorylation(GO:0046854)
0.0 0.2 GO:0032258 CVT pathway(GO:0032258)
0.0 0.0 GO:0042173 regulation of sporulation resulting in formation of a cellular spore(GO:0042173)
0.0 0.7 GO:0009272 fungal-type cell wall biogenesis(GO:0009272)
0.0 0.2 GO:0001101 response to acid chemical(GO:0001101)
0.0 0.0 GO:0045117 azole transport(GO:0045117)
0.0 0.0 GO:0043207 immune effector process(GO:0002252) immune system process(GO:0002376) response to virus(GO:0009615) response to external biotic stimulus(GO:0043207) defense response to virus(GO:0051607) response to other organism(GO:0051707) defense response to other organism(GO:0098542)
0.0 0.1 GO:0000349 generation of catalytic spliceosome for first transesterification step(GO:0000349)
0.0 0.1 GO:0008053 mitochondrial fusion(GO:0008053)
0.0 0.1 GO:0006276 plasmid maintenance(GO:0006276)
0.0 0.1 GO:0030100 regulation of endocytosis(GO:0030100)
0.0 0.0 GO:0015793 glycerol transport(GO:0015793)
0.0 0.1 GO:0018065 protein-cofactor linkage(GO:0018065)
0.0 0.0 GO:0042773 respiratory electron transport chain(GO:0022904) ATP synthesis coupled electron transport(GO:0042773) mitochondrial ATP synthesis coupled electron transport(GO:0042775)
0.0 0.1 GO:0009743 response to carbohydrate(GO:0009743) response to hexose(GO:0009746) response to glucose(GO:0009749) response to monosaccharide(GO:0034284)
0.0 0.1 GO:0043487 regulation of RNA stability(GO:0043487) regulation of mRNA stability(GO:0043488)
0.0 0.4 GO:0006612 protein targeting to membrane(GO:0006612)
0.0 0.0 GO:0018023 peptidyl-lysine trimethylation(GO:0018023)
0.0 0.0 GO:0007076 mitotic chromosome condensation(GO:0007076)
0.0 0.0 GO:0042182 ketone catabolic process(GO:0042182) L-kynurenine metabolic process(GO:0097052) L-kynurenine catabolic process(GO:0097053)
0.0 0.0 GO:0006020 inositol metabolic process(GO:0006020)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.0 GO:0005771 multivesicular body(GO:0005771)
0.3 0.8 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.2 1.5 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.2 0.5 GO:0000274 mitochondrial proton-transporting ATP synthase, stator stalk(GO:0000274) proton-transporting ATP synthase, stator stalk(GO:0045265)
0.2 0.5 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.2 0.6 GO:0097042 extrinsic component of fungal-type vacuolar membrane(GO:0097042)
0.1 0.4 GO:0031166 integral component of vacuolar membrane(GO:0031166)
0.1 0.5 GO:0030062 mitochondrial tricarboxylic acid cycle enzyme complex(GO:0030062)
0.1 0.3 GO:0030870 Mre11 complex(GO:0030870)
0.1 0.3 GO:0000148 1,3-beta-D-glucan synthase complex(GO:0000148)
0.1 0.2 GO:0000113 nucleotide-excision repair factor 4 complex(GO:0000113)
0.1 0.2 GO:0031422 RecQ helicase-Topo III complex(GO:0031422)
0.1 0.3 GO:0031932 TORC2 complex(GO:0031932)
0.1 0.2 GO:0032807 DNA ligase IV complex(GO:0032807)
0.1 0.5 GO:0005775 vacuolar lumen(GO:0005775)
0.0 0.1 GO:0072687 meiotic spindle(GO:0072687)
0.0 0.1 GO:0030896 checkpoint clamp complex(GO:0030896)
0.0 2.0 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.5 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.0 0.1 GO:0005845 mRNA cap binding complex(GO:0005845)
0.0 0.2 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 0.2 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276) proton-transporting ATP synthase complex, coupling factor F(o)(GO:0045263)
0.0 0.4 GO:0030677 ribonuclease P complex(GO:0030677)
0.0 0.4 GO:0045275 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0 0.7 GO:0048471 perinuclear region of cytoplasm(GO:0048471)
0.0 0.1 GO:0044426 cell wall part(GO:0044426) external encapsulating structure part(GO:0044462)
0.0 0.0 GO:0000974 Prp19 complex(GO:0000974)
0.0 0.1 GO:0033309 SBF transcription complex(GO:0033309)
0.0 0.1 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.0 0.2 GO:0032221 Rpd3S complex(GO:0032221)
0.0 0.3 GO:0033101 cellular bud membrane(GO:0033101)
0.0 0.2 GO:0034967 Set3 complex(GO:0034967)
0.0 0.8 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.0 0.1 GO:0035649 Nrd1 complex(GO:0035649)
0.0 0.1 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.0 0.2 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0 0.3 GO:0008287 protein serine/threonine phosphatase complex(GO:0008287) phosphatase complex(GO:1903293)
0.0 0.1 GO:0030061 mitochondrial crista(GO:0030061)
0.0 0.1 GO:0008623 CHRAC(GO:0008623)
0.0 0.5 GO:0005802 trans-Golgi network(GO:0005802)
0.0 0.0 GO:0001400 mating projection base(GO:0001400)
0.0 0.2 GO:0045277 mitochondrial respiratory chain complex IV(GO:0005751) respiratory chain complex IV(GO:0045277)
0.0 1.1 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.0 0.1 GO:0032806 carboxy-terminal domain protein kinase complex(GO:0032806)
0.0 0.1 GO:0035361 Cul8-RING ubiquitin ligase complex(GO:0035361)
0.0 0.3 GO:0071006 U2-type catalytic step 1 spliceosome(GO:0071006) catalytic step 1 spliceosome(GO:0071012)
0.0 0.3 GO:0030014 CCR4-NOT complex(GO:0030014)
0.0 0.2 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.3 GO:0000152 nuclear ubiquitin ligase complex(GO:0000152)
0.0 0.2 GO:0000142 cellular bud neck contractile ring(GO:0000142)
0.0 0.1 GO:0000112 nucleotide-excision repair factor 3 complex(GO:0000112)
0.0 0.4 GO:0042764 prospore membrane(GO:0005628) intracellular immature spore(GO:0042763) ascospore-type prospore(GO:0042764)
0.0 0.1 GO:0031010 ISWI-type complex(GO:0031010)
0.0 0.1 GO:0000836 Hrd1p ubiquitin ligase complex(GO:0000836) Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.0 1.6 GO:0000794 condensed nuclear chromosome(GO:0000794)
0.0 0.0 GO:0032116 SMC loading complex(GO:0032116)
0.0 0.6 GO:0019898 extrinsic component of membrane(GO:0019898)
0.0 0.1 GO:0005823 central plaque of spindle pole body(GO:0005823)
0.0 0.0 GO:0031391 Elg1 RFC-like complex(GO:0031391)
0.0 0.1 GO:0098552 side of membrane(GO:0098552) cytoplasmic side of membrane(GO:0098562)
0.0 0.2 GO:0031231 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.0 0.1 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 0.7 GO:0010008 endosome membrane(GO:0010008)
0.0 0.5 GO:0000131 incipient cellular bud site(GO:0000131)
0.0 1.6 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.0 0.0 GO:0055087 Ski complex(GO:0055087)
0.0 0.1 GO:0031390 Ctf18 RFC-like complex(GO:0031390)
0.0 0.0 GO:0051233 spindle midzone(GO:0051233)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.6 GO:0005537 mannose binding(GO:0005537)
0.4 1.6 GO:0016639 oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor(GO:0016639)
0.3 0.9 GO:0016406 carnitine O-acetyltransferase activity(GO:0004092) carnitine O-acyltransferase activity(GO:0016406)
0.2 0.7 GO:0004866 endopeptidase inhibitor activity(GO:0004866) peptidase inhibitor activity(GO:0030414)
0.2 0.8 GO:0004737 pyruvate decarboxylase activity(GO:0004737)
0.2 0.5 GO:0098518 polynucleotide phosphatase activity(GO:0098518)
0.2 0.7 GO:0015603 siderophore transmembrane transporter activity(GO:0015343) iron chelate transmembrane transporter activity(GO:0015603) siderophore transporter activity(GO:0042927)
0.2 1.4 GO:0031072 heat shock protein binding(GO:0031072)
0.2 0.5 GO:0016880 AMP binding(GO:0016208) acid-ammonia (or amide) ligase activity(GO:0016880)
0.1 0.4 GO:0042947 alpha-glucoside transmembrane transporter activity(GO:0015151) glucoside transmembrane transporter activity(GO:0042947)
0.1 0.7 GO:0050072 m7G(5')pppN diphosphatase activity(GO:0050072)
0.1 0.6 GO:0004396 hexokinase activity(GO:0004396)
0.1 0.7 GO:0008601 protein phosphatase type 2A regulator activity(GO:0008601)
0.1 0.4 GO:0008972 hydroxymethylpyrimidine kinase activity(GO:0008902) phosphomethylpyrimidine kinase activity(GO:0008972)
0.1 1.4 GO:0015203 polyamine transmembrane transporter activity(GO:0015203)
0.1 0.4 GO:0030060 L-malate dehydrogenase activity(GO:0030060)
0.1 0.4 GO:0003954 NADH dehydrogenase activity(GO:0003954) NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.1 0.6 GO:0050253 triglyceride lipase activity(GO:0004806) retinyl-palmitate esterase activity(GO:0050253)
0.1 1.8 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.1 0.3 GO:0004564 beta-fructofuranosidase activity(GO:0004564) sucrose alpha-glucosidase activity(GO:0004575)
0.1 0.3 GO:0004088 carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity(GO:0004088)
0.1 0.3 GO:0003843 1,3-beta-D-glucan synthase activity(GO:0003843)
0.1 0.4 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.1 0.8 GO:0008519 ammonium transmembrane transporter activity(GO:0008519)
0.1 0.4 GO:0015556 C4-dicarboxylate transmembrane transporter activity(GO:0015556)
0.1 0.3 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.1 0.3 GO:0003691 double-stranded telomeric DNA binding(GO:0003691)
0.1 0.5 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.1 0.3 GO:0000156 phosphorelay response regulator activity(GO:0000156)
0.1 0.3 GO:0001097 TFIIH-class transcription factor binding(GO:0001097)
0.1 0.2 GO:0004805 trehalose-phosphatase activity(GO:0004805)
0.1 0.2 GO:0032183 SUMO binding(GO:0032183)
0.1 0.5 GO:0070001 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.1 0.3 GO:0004448 isocitrate dehydrogenase activity(GO:0004448)
0.1 0.7 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.1 0.4 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.1 0.2 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.1 0.4 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.1 0.2 GO:0004724 magnesium-dependent protein serine/threonine phosphatase activity(GO:0004724)
0.1 0.2 GO:0016411 acylglycerol O-acyltransferase activity(GO:0016411)
0.1 1.2 GO:0042802 identical protein binding(GO:0042802)
0.1 0.4 GO:0015294 solute:cation symporter activity(GO:0015294)
0.1 1.1 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843) thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.1 0.2 GO:0034596 phosphatidylinositol phosphate 4-phosphatase activity(GO:0034596) phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812)
0.1 0.3 GO:0016635 oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor(GO:0016635)
0.0 0.1 GO:0004100 chitin synthase activity(GO:0004100)
0.0 0.1 GO:0016289 CoA hydrolase activity(GO:0016289)
0.0 0.4 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.0 0.2 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 0.3 GO:0000014 single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.0 0.2 GO:0016886 ligase activity, forming phosphoric ester bonds(GO:0016886)
0.0 0.4 GO:0031386 protein tag(GO:0031386)
0.0 0.5 GO:0008599 protein phosphatase type 1 regulator activity(GO:0008599)
0.0 0.2 GO:0004030 aldehyde dehydrogenase (NAD) activity(GO:0004029) aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030)
0.0 1.7 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077) transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 0.0 GO:0032137 guanine/thymine mispair binding(GO:0032137)
0.0 0.2 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0 0.4 GO:0004526 ribonuclease P activity(GO:0004526)
0.0 0.3 GO:0000982 transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0000982)
0.0 0.3 GO:0015085 calcium ion transmembrane transporter activity(GO:0015085)
0.0 0.2 GO:0070403 NAD+ binding(GO:0070403)
0.0 0.3 GO:0016884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884)
0.0 0.3 GO:0016679 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.0 0.1 GO:0016435 rRNA (guanine) methyltransferase activity(GO:0016435)
0.0 0.1 GO:0030976 thiamine pyrophosphate binding(GO:0030976)
0.0 0.1 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.0 0.2 GO:0000400 four-way junction DNA binding(GO:0000400)
0.0 0.2 GO:0015923 alpha-mannosidase activity(GO:0004559) mannosidase activity(GO:0015923)
0.0 0.1 GO:0019783 ubiquitin-like protein-specific protease activity(GO:0019783)
0.0 0.3 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.0 0.1 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0 0.2 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 0.1 GO:0019789 SUMO transferase activity(GO:0019789)
0.0 0.0 GO:0043813 phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity(GO:0043813)
0.0 0.0 GO:0004558 alpha-1,4-glucosidase activity(GO:0004558)
0.0 0.1 GO:0019212 protein phosphatase inhibitor activity(GO:0004864) phosphatase inhibitor activity(GO:0019212)
0.0 0.6 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides(GO:0016811)
0.0 0.1 GO:0004032 alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.0 0.1 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity(GO:0004723)
0.0 0.1 GO:0005347 ATP transmembrane transporter activity(GO:0005347) ATP:ADP antiporter activity(GO:0005471) ADP transmembrane transporter activity(GO:0015217)
0.0 0.4 GO:0008301 DNA binding, bending(GO:0008301)
0.0 0.1 GO:0070336 flap-structured DNA binding(GO:0070336)
0.0 0.1 GO:0042736 NAD+ kinase activity(GO:0003951) NADH kinase activity(GO:0042736)
0.0 0.1 GO:0008897 holo-[acyl-carrier-protein] synthase activity(GO:0008897)
0.0 0.2 GO:0004177 aminopeptidase activity(GO:0004177)
0.0 0.2 GO:0015002 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.2 GO:0044389 ubiquitin protein ligase binding(GO:0031625) ubiquitin-like protein ligase binding(GO:0044389)
0.0 0.1 GO:0016531 copper chaperone activity(GO:0016531)
0.0 0.1 GO:0016684 peroxidase activity(GO:0004601) oxidoreductase activity, acting on peroxide as acceptor(GO:0016684)
0.0 0.1 GO:0016668 oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor(GO:0016668)
0.0 1.7 GO:0004672 protein kinase activity(GO:0004672)
0.0 0.5 GO:0050662 coenzyme binding(GO:0050662)
0.0 0.1 GO:0016782 transferase activity, transferring sulfur-containing groups(GO:0016782)
0.0 0.5 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 0.1 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 1.0 GO:0051082 unfolded protein binding(GO:0051082)
0.0 0.1 GO:0000146 microfilament motor activity(GO:0000146)
0.0 0.1 GO:0030145 manganese ion binding(GO:0030145)
0.0 0.2 GO:0051287 NAD binding(GO:0051287)
0.0 0.2 GO:0031491 nucleosome binding(GO:0031491)
0.0 0.1 GO:0016638 oxidoreductase activity, acting on the CH-NH2 group of donors(GO:0016638)
0.0 1.2 GO:0005543 phospholipid binding(GO:0005543)
0.0 0.1 GO:0008198 ferrous iron binding(GO:0008198)
0.0 0.1 GO:0015079 potassium ion transmembrane transporter activity(GO:0015079)
0.0 0.1 GO:0045182 translation regulator activity(GO:0045182)
0.0 0.6 GO:0030695 GTPase regulator activity(GO:0030695)
0.0 0.1 GO:0005487 nucleocytoplasmic transporter activity(GO:0005487)
0.0 0.0 GO:0045118 azole transporter activity(GO:0045118)
0.0 0.1 GO:0000384 first spliceosomal transesterification activity(GO:0000384)
0.0 0.0 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.7 GO:0019787 ubiquitin-like protein transferase activity(GO:0019787)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.5 PID ERBB4 PATHWAY ErbB4 signaling events
0.2 0.4 PID IL4 2PATHWAY IL4-mediated signaling events
0.2 0.5 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.1 0.2 PID ATM PATHWAY ATM pathway
0.1 0.2 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.1 0.2 PID E2F PATHWAY E2F transcription factor network
0.1 0.2 PID CXCR4 PATHWAY CXCR4-mediated signaling events
0.0 0.1 PID P73PATHWAY p73 transcription factor network
0.0 0.0 PID ERBB1 RECEPTOR PROXIMAL PATHWAY EGF receptor (ErbB1) signaling pathway
0.0 0.1 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.0 0.2 PID FANCONI PATHWAY Fanconi anemia pathway
0.0 34.1 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 0.1 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 0.1 PID PLK1 PATHWAY PLK1 signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.5 REACTOME SHC1 EVENTS IN ERBB4 SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.2 1.0 REACTOME PYRUVATE METABOLISM AND CITRIC ACID TCA CYCLE Genes involved in Pyruvate metabolism and Citric Acid (TCA) cycle
0.2 0.7 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.2 0.7 REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS Genes involved in Glycerophospholipid biosynthesis
0.1 0.3 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.1 0.2 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.1 0.7 REACTOME GLUCOSE METABOLISM Genes involved in Glucose metabolism
0.0 0.2 REACTOME E2F MEDIATED REGULATION OF DNA REPLICATION Genes involved in E2F mediated regulation of DNA replication
0.0 0.0 REACTOME PI3K EVENTS IN ERBB2 SIGNALING Genes involved in PI3K events in ERBB2 signaling
0.0 0.1 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 34.1 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 0.1 REACTOME DNA REPAIR Genes involved in DNA Repair
0.0 0.1 REACTOME CLEAVAGE OF GROWING TRANSCRIPT IN THE TERMINATION REGION Genes involved in Cleavage of Growing Transcript in the Termination Region