Gene Symbol | Gene ID | Gene Info |
---|---|---|
XBP1
|
S000001363 | Transcriptional repressor |
Promoter | Log-likelihood | Transcript | Gene | Gene Info |
---|---|---|---|---|
YFR055W | 37.95 |
IRC7
|
Putative cystathionine beta-lyase; involved in copper ion homeostasis and sulfur metabolism; null mutant displays increased levels of spontaneous Rad52p foci; expression induced by nitrogen limitation in a GLN3, GAT1-dependent manner |
|
YFR056C | 33.38 |
Dubious open reading frame unlikely to encode a protein based on available experimental and comparative sequence data; partially overlaps the uncharacterized gene YFR055W |
||
YDR033W | 24.13 |
MRH1
|
Protein that localizes primarily to the plasma membrane, also found at the nuclear envelope; the authentic, non-tagged protein is detected in mitochondria in a phosphorylated state; has similarity to Hsp30p and Yro2p |
|
YGR108W | 22.26 |
CLB1
|
B-type cyclin involved in cell cycle progression; activates Cdc28p to promote the transition from G2 to M phase; accumulates during G2 and M, then targeted via a destruction box motif for ubiquitin-mediated degradation by the proteasome |
|
YML052W | 20.50 |
SUR7
|
Putative integral membrane protein; component of eisosomes; associated with endocytosis, along with Pil1p and Lsp1p; sporulation and plasma membrane sphingolipid content are altered in mutants |
|
YDR044W | 20.23 |
HEM13
|
Coproporphyrinogen III oxidase, an oxygen requiring enzyme that catalyzes the sixth step in the heme biosynthetic pathway; localizes to the mitochondrial inner membrane; transcription is repressed by oxygen and heme (via Rox1p and Hap1p) |
|
YPR119W | 19.83 |
CLB2
|
B-type cyclin involved in cell cycle progression; activates Cdc28p to promote the transition from G2 to M phase; accumulates during G2 and M, then targeted via a destruction box motif for ubiquitin-mediated degradation by the proteasome |
|
YJL158C | 18.55 |
CIS3
|
Mannose-containing glycoprotein constituent of the cell wall; member of the PIR (proteins with internal repeats) family |
|
YCR018C | 18.52 |
SRD1
|
Protein involved in the processing of pre-rRNA to mature rRNA; contains a C2/C2 zinc finger motif; srd1 mutation suppresses defects caused by the rrp1-1 mutation |
|
YMR032W | 17.46 |
HOF1
|
Bud neck-localized, SH3 domain-containing protein required for cytokinesis; regulates actomyosin ring dynamics and septin localization; interacts with the formins, Bni1p and Bnr1p, and with Cyk3p, Vrp1p, and Bni5p |
|
YKR038C | 16.71 |
KAE1
|
Putative glycoprotease proposed to be in transcription as a component of the EKC protein complex with Bud32p, Cgi121p, Pcc1p, and Gon7p; also identified as a component of the KEOPS protein complex |
|
YLR180W | 15.74 |
SAM1
|
S-adenosylmethionine synthetase, catalyzes transfer of the adenosyl group of ATP to the sulfur atom of methionine; one of two differentially regulated isozymes (Sam1p and Sam2p) |
|
YLR328W | 14.91 |
NMA1
|
Nicotinic acid mononucleotide adenylyltransferase, involved in pathways of NAD biosynthesis, including the de novo, NAD(+) salvage, and nicotinamide riboside salvage pathways |
|
YKR013W | 14.49 |
PRY2
|
Protein of unknown function, has similarity to Pry1p and Pry3p and to the plant PR-1 class of pathogen related proteins |
|
YMR199W | 13.93 |
CLN1
|
G1 cyclin involved in regulation of the cell cycle; activates Cdc28p kinase to promote the G1 to S phase transition; late G1 specific expression depends on transcription factor complexes, MBF (Swi6p-Mbp1p) and SBF (Swi6p-Swi4p) |
|
YKL128C | 13.67 |
PMU1
|
Putative phosphomutase, contains a region homologous to the active site of phosphomutases; overexpression suppresses the histidine auxotrophy of an ade3 ade16 ade17 triple mutant and the temperature sensitivity of a tps2 mutant |
|
YJR094W-A | 13.11 |
RPL43B
|
Protein component of the large (60S) ribosomal subunit, identical to Rpl43Ap and has similarity to rat L37a ribosomal protein |
|
YIR021W | 13.06 |
MRS1
|
Protein required for the splicing of two mitochondrial group I introns (BI3 in COB and AI5beta in COX1); forms a splicing complex, containing four subunits of Mrs1p and two subunits of the BI3-encoded maturase, that binds to the BI3 RNA |
|
YHR163W | 12.72 |
SOL3
|
6-phosphogluconolactonase, catalyzes the second step of the pentose phosphate pathway; weak multicopy suppressor of los1-1 mutation; homologous to Sol2p and Sol1p |
|
YBR011C | 12.65 |
IPP1
|
Cytoplasmic inorganic pyrophosphatase (PPase), catalyzes the rapid exchange of oxygens from Pi with water, highly expressed and essential for viability, active-site residues show identity to those from E. coli PPase |
|
YGL157W | 12.40 |
Oxidoreductase, catalyzes NADPH-dependent reduction of the bicyclic diketone bicyclo[2.2.2]octane-2,6-dione (BCO2,6D) to the chiral ketoalcohol (1R,4S,6S)-6-hydroxybicyclo[2.2.2]octane-2-one (BCO2one6ol) |
||
YMR307W | 12.34 |
GAS1
|
Beta-1,3-glucanosyltransferase, required for cell wall assembly; localizes to the cell surface via a glycosylphosphatidylinositol (GPI) anchor |
|
YKR012C | 12.30 |
Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified gene PRY2 |
||
YGR185C | 12.23 |
TYS1
|
Cytoplasmic tyrosyl-tRNA synthetase, class I aminoacyl-tRNA synthetase that aminoacylates tRNA(Tyr), required for cytoplasmic protein synthesis, interacts with positions 34 and 35 of the anticodon of tRNATyr |
|
YDR047W | 12.18 |
HEM12
|
Uroporphyrinogen decarboxylase, catalyzes the fifth step in the heme biosynthetic pathway; localizes to both the cytoplasm and nucleus; activity inhibited by Cu2+, Zn2+, Fe2+, Fe3+ and sulfhydryl-specific reagents |
|
YJR105W | 11.98 |
ADO1
|
Adenosine kinase, required for the utilization of S-adenosylmethionine (AdoMet); may be involved in recycling adenosine produced through the methyl cycle |
|
YGL097W | 11.71 |
SRM1
|
Nucleotide exchange factor for Gsp1p, localizes to the nucleus, required for nucleocytoplasmic trafficking of macromolecules; suppressor of the pheromone response pathway; potentially phosphorylated by Cdc28p |
|
YKR092C | 11.53 |
SRP40
|
Nucleolar, serine-rich protein with a role in preribosome assembly or transport; may function as a chaperone of small nucleolar ribonucleoprotein particles (snoRNPs); immunologically and structurally to rat Nopp140 |
|
YMR001C-A | 11.47 |
Putative protein of unknown function |
||
YLL045C | 11.42 |
RPL8B
|
Ribosomal protein L4 of the large (60S) ribosomal subunit, nearly identical to Rpl8Ap and has similarity to rat L7a ribosomal protein; mutation results in decreased amounts of free 60S subunits |
|
YLR257W | 11.24 |
Putative protein of unknown function |
||
YDR098C | 11.23 |
GRX3
|
Hydroperoxide and superoxide-radical responsive glutathione-dependent oxidoreductase; monothiol glutaredoxin subfamily member along with Grx4p and Grx5p; protects cells from oxidative damage |
|
YPL245W | 11.14 |
Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to both the nucleus and the cytoplasm |
||
YDR046C | 11.10 |
BAP3
|
Amino acid permease involved in the uptake of cysteine, leucine, isoleucine and valine |
|
YBR084W | 10.89 |
MIS1
|
Mitochondrial C1-tetrahydrofolate synthase, involved in interconversion between different oxidation states of tetrahydrofolate (THF); provides activities of formyl-THF synthetase, methenyl-THF cyclohydrolase, and methylene-THF dehydrogenase |
|
YKL127W | 10.71 |
PGM1
|
Phosphoglucomutase, minor isoform; catalyzes the conversion from glucose-1-phosphate to glucose-6-phosphate, which is a key step in hexose metabolism |
|
YNL066W | 10.50 |
SUN4
|
Cell wall protein related to glucanases, possibly involved in cell wall septation; member of the SUN family |
|
YOR101W | 10.36 |
RAS1
|
GTPase involved in G-protein signaling in the adenylate cyclase activating pathway, plays a role in cell proliferation; localized to the plasma membrane; homolog of mammalian RAS proto-oncogenes |
|
YHR162W | 10.19 |
Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the mitochondrion |
||
YPR074C | 10.08 |
TKL1
|
Transketolase, similar to Tkl2p; catalyzes conversion of xylulose-5-phosphate and ribose-5-phosphate to sedoheptulose-7-phosphate and glyceraldehyde-3-phosphate in the pentose phosphate pathway; needed for synthesis of aromatic amino acids |
|
YLR179C | 10.06 |
Protein of unknown function, transcription is activated by paralogous proteins Yrm1p and Yrr1p along with proteins involved in multidrug resistance; GFP-tagged protein localizes to the cytoplasm and nucleus; YLR179C is not essential |
||
YOR315W | 10.06 |
SFG1
|
Nuclear protein, putative transcription factor required for growth of superficial pseudohyphae (which do not invade the agar substrate) but not for invasive pseudohyphal growth; may act together with Phd1p; potential Cdc28p substrate |
|
YOR222W | 10.04 |
ODC2
|
Mitochondrial inner membrane transporter, exports 2-oxoadipate and 2-oxoglutarate from the mitochondrial matrix to the cytosol for use in lysine and glutamate biosynthesis and in lysine catabolism |
|
YGR040W | 9.93 |
KSS1
|
Mitogen-activated protein kinase (MAPK) involved in signal transduction pathways that control filamentous growth and pheromone response; the KSS1 gene is nonfunctional in S288C strains and functional in W303 strains |
|
YNL010W | 9.76 |
Putative protein of unknown function with similarity to phosphoserine phosphatases; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus; homozygous diploid mutant shows an increase in glycogen accumulation |
||
YGL202W | 9.63 |
ARO8
|
Aromatic aminotransferase I, expression is regulated by general control of amino acid biosynthesis |
|
YPL273W | 9.59 |
SAM4
|
S-adenosylmethionine-homocysteine methyltransferase, functions along with Mht1p in the conversion of S-adenosylmethionine (AdoMet) to methionine to control the methionine/AdoMet ratio |
|
YOR226C | 9.57 |
ISU2
|
Conserved protein of the mitochondrial matrix, required for synthesis of mitochondrial and cytosolic iron-sulfur proteins, performs a scaffolding function in mitochondria during Fe/S cluster assembly; isu1 isu2 double mutant is inviable |
|
YER043C | 9.50 |
SAH1
|
S-adenosyl-L-homocysteine hydrolase, catabolizes S-adenosyl-L-homocysteine which is formed after donation of the activated methyl group of S-adenosyl-L-methionine (AdoMet) to an acceptor |
|
YAL003W | 9.42 |
EFB1
|
Translation elongation factor 1 beta; stimulates nucleotide exchange to regenerate EF-1 alpha-GTP for the next elongation cycle; part of the EF-1 complex, which facilitates binding of aminoacyl-tRNA to the ribosomal A site |
|
YDL055C | 9.35 |
PSA1
|
GDP-mannose pyrophosphorylase (mannose-1-phosphate guanyltransferase), synthesizes GDP-mannose from GTP and mannose-1-phosphate in cell wall biosynthesis; required for normal cell wall structure |
|
YGR279C | 9.20 |
SCW4
|
Cell wall protein with similarity to glucanases; scw4 scw10 double mutants exhibit defects in mating |
|
YDR502C | 9.17 |
SAM2
|
S-adenosylmethionine synthetase, catalyzes transfer of the adenosyl group of ATP to the sulfur atom of methionine; one of two differentially regulated isozymes (Sam1p and Sam2p) |
|
YDR133C | 9.08 |
Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps YDR134C |
||
YOL086C | 8.93 |
ADH1
|
Alcohol dehydrogenase, fermentative isozyme active as homo- or heterotetramers; required for the reduction of acetaldehyde to ethanol, the last step in the glycolytic pathway |
|
YDR023W | 8.93 |
SES1
|
Cytosolic seryl-tRNA synthetase, class II aminoacyl-tRNA synthetase that aminoacylates tRNA(Ser), displays tRNA-dependent amino acid recognition which enhances discrimination of the serine substrate, interacts with peroxin Pex21p |
|
YNR001W-A | 8.87 |
Dubious open reading frame unlikely to encode a functional protein; identified by homology |
||
YLR110C | 8.70 |
CCW12
|
Cell wall mannoprotein, mutants are defective in mating and agglutination, expression is downregulated by alpha-factor |
|
YLR314C | 8.67 |
CDC3
|
Component of the septin ring of the mother-bud neck that is required for cytokinesis; septins recruit proteins to the neck and can act as a barrier to diffusion at the membrane, and they comprise the 10nm filaments seen with EM |
|
YGL179C | 8.65 |
TOS3
|
Protein kinase, related to and functionally redundant with Elm1p and Sak1p for the phosphorylation and activation of Snf1p; functionally orthologous to LKB1, a mammalian kinase associated with Peutz-Jeghers cancer-susceptibility syndrome |
|
YGR234W | 8.63 |
YHB1
|
Nitric oxide oxidoreductase, flavohemoglobin involved in nitric oxide detoxification; plays a role in the oxidative and nitrosative stress responses |
|
YEL040W | 8.51 |
UTR2
|
Cell wall protein that functions in the transfer of chitin to beta(1-6)glucan; putative chitin transglycosidase; glycosylphosphatidylinositol (GPI)-anchored protein localized to the bud neck; has a role in cell wall maintenance |
|
YJL011C | 8.48 |
RPC17
|
RNA polymerase III subunit C17; physically interacts with C31, C11, and TFIIIB70; may be involved in the recruitment of pol III by the preinitiation complex |
|
YPR170W-B | 8.43 |
Putative protein of unknown function, conserved in fungi; partially overlaps the dubious genes YPR169W-A, YPR170W-A and YRP170C |
||
YDR261C | 8.38 |
EXG2
|
Exo-1,3-beta-glucanase, involved in cell wall beta-glucan assembly; may be anchored to the plasma membrane via a glycosylphosphatidylinositol (GPI) anchor |
|
YIL121W | 8.29 |
QDR2
|
Multidrug transporter of the major facilitator superfamily, required for resistance to quinidine, barban, cisplatin, and bleomycin; may have a role in potassium uptake |
|
YGR264C | 8.27 |
MES1
|
Methionyl-tRNA synthetase, forms a complex with glutamyl-tRNA synthetase (Gus1p) and Arc1p, which increases the catalytic efficiency of both tRNA synthetases; also has a role in nuclear export of tRNAs |
|
YBR121C | 8.16 |
GRS1
|
Cytoplasmic and mitochondrial glycyl-tRNA synthase that ligates glycine to the cognate anticodon bearing tRNA; transcription termination factor that may interact with the 3'-end of pre-mRNA to promote 3'-end formation |
|
YLR372W | 8.14 |
SUR4
|
Elongase, involved in fatty acid and sphingolipid biosynthesis; synthesizes very long chain 20-26-carbon fatty acids from C18-CoA primers; involved in regulation of sphingolipid biosynthesis |
|
YHR094C | 7.98 |
HXT1
|
Low-affinity glucose transporter of the major facilitator superfamily, expression is induced by Hxk2p in the presence of glucose and repressed by Rgt1p when glucose is limiting |
|
YBR162C | 7.90 |
TOS1
|
Covalently-bound cell wall protein of unknown function; identified as a cell cycle regulated SBF target gene; deletion mutants are highly resistant to treatment with beta-1,3-glucanase; has sequence similarity to YJL171C |
|
YDR345C | 7.85 |
HXT3
|
Low affinity glucose transporter of the major facilitator superfamily, expression is induced in low or high glucose conditions |
|
YGR249W | 7.82 |
MGA1
|
Protein similar to heat shock transcription factor; multicopy suppressor of pseudohyphal growth defects of ammonium permease mutants |
|
YHR216W | 7.80 |
IMD2
|
Inosine monophosphate dehydrogenase, catalyzes the first step of GMP biosynthesis, expression is induced by mycophenolic acid resulting in resistance to the drug, expression is repressed by nutrient limitation |
|
YHR201C | 7.63 |
PPX1
|
Exopolyphosphatase, hydrolyzes inorganic polyphosphate (poly P) into Pi residues; located in the cytosol, plasma membrane, and mitochondrial matrix |
|
YGR265W | 7.61 |
Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified ORF MES1/YGR264C, which encodes methionyl-tRNA synthetase |
||
YBR012C | 7.56 |
Dubious open reading frame, unlikely to encode a functional protein; expression induced by iron-regulated transcriptional activator Aft2p |
||
YOL039W | 7.55 |
RPP2A
|
Ribosomal protein P2 alpha, a component of the ribosomal stalk, which is involved in the interaction between translational elongation factors and the ribosome; regulates the accumulation of P1 (Rpp1Ap and Rpp1Bp) in the cytoplasm |
|
YFR054C | 7.51 |
Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data |
||
YHR123W | 7.51 |
EPT1
|
sn-1,2-diacylglycerol ethanolamine- and cholinephosphotranferase; not essential for viability |
|
YML056C | 7.38 |
IMD4
|
Inosine monophosphate dehydrogenase, catalyzes the first step of GMP biosynthesis, member of a four-gene family in S. cerevisiae, constitutively expressed |
|
YPL246C | 7.37 |
RBD2
|
Possible rhomboid protease, has similarity to eukaryotic rhomboid proteases including Pcp1p |
|
YHR144C | 7.35 |
DCD1
|
Deoxycytidine monophosphate (dCMP) deaminase required for dCTP and dTTP synthesis; expression is NOT cell cycle regulated |
|
YER124C | 7.28 |
DSE1
|
Daughter cell-specific protein, may participate in pathways regulating cell wall metabolism; deletion affects cell separation after division and sensitivity to drugs targeted against the cell wall |
|
YKL218C | 7.28 |
SRY1
|
3-hydroxyaspartate dehydratase, deaminates L-threo-3-hydroxyaspartate to form oxaloacetate and ammonia; required for survival in the presence of hydroxyaspartate |
|
YLR367W | 7.23 |
RPS22B
|
Protein component of the small (40S) ribosomal subunit; nearly identical to Rps22Ap and has similarity to E. coli S8 and rat S15a ribosomal proteins |
|
YOR312C | 7.14 |
RPL20B
|
Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl20Ap and has similarity to rat L18a ribosomal protein |
|
YPR157W | 7.11 |
Putative protein of unknown function; induced by treatment with 8-methoxypsoralen and UVA irradiation |
||
YPL075W | 7.09 |
GCR1
|
Transcriptional activator of genes involved in glycolysis; DNA-binding protein that interacts and functions with the transcriptional activator Gcr2p |
|
YAL012W | 7.09 |
CYS3
|
Cystathionine gamma-lyase, catalyzes one of the two reactions involved in the transsulfuration pathway that yields cysteine from homocysteine with the intermediary formation of cystathionine |
|
YPR170W-A | 7.00 |
Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data; identified by expression profiling and mass spectrometry |
||
YER137C | 6.87 |
Putative protein of unknown function |
||
YHR043C | 6.84 |
DOG2
|
2-deoxyglucose-6-phosphate phosphatase, member of a family of low molecular weight phosphatases, similar to Dog1p, induced by oxidative and osmotic stress, confers 2-deoxyglucose resistance when overexpressed |
|
YNL160W | 6.80 |
YGP1
|
Cell wall-related secretory glycoprotein; induced by nutrient deprivation-associated growth arrest and upon entry into stationary phase; may be involved in adaptation prior to stationary phase entry; has similarity to Sps100p |
|
YHR182C-A | 6.76 |
Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data |
||
YHR183W | 6.71 |
GND1
|
6-phosphogluconate dehydrogenase (decarboxylating), catalyzes an NADPH regenerating reaction in the pentose phosphate pathway; required for growth on D-glucono-delta-lactone and adaptation to oxidative stress |
|
YHR089C | 6.70 |
GAR1
|
Protein component of the H/ACA snoRNP pseudouridylase complex, involved in the modification and cleavage of the 18S pre-rRNA |
|
YGR106C | 6.68 |
VOA1
|
Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the vacuolar memebrane |
|
YKL164C | 6.63 |
PIR1
|
O-glycosylated protein required for cell wall stability; attached to the cell wall via beta-1,3-glucan; mediates mitochondrial translocation of Apn1p; expression regulated by the cell integrity pathway and by Swi5p during the cell cycle |
|
YDR309C | 6.57 |
GIC2
|
Redundant rho-like GTPase Cdc42p effector; homolog of Gic1p; involved in initiation of budding and cellular polarization; interacts with Cdc42p via the Cdc42/Rac-interactive binding (CRIB) domain and with PI(4,5)P2 via a polybasic region |
|
YBR067C | 6.55 |
TIP1
|
Major cell wall mannoprotein with possible lipase activity; transcription is induced by heat- and cold-shock; member of the Srp1p/Tip1p family of serine-alanine-rich proteins |
|
YNL141W | 6.51 |
AAH1
|
Adenine deaminase (adenine aminohydrolase), converts adenine to hypoxanthine; involved in purine salvage; transcriptionally regulated by nutrient levels and growth phase; Aah1p degraded upon entry into quiescence via SCF and the proteasome |
|
YGR107W | 6.48 |
Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data |
||
YBR096W | 6.39 |
Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the ER |
||
YDR497C | 6.35 |
ITR1
|
Myo-inositol transporter with strong similarity to the minor myo-inositol transporter Itr2p, member of the sugar transporter superfamily; expression is repressed by inositol and choline via Opi1p and derepressed via Ino2p and Ino4p |
|
YAL029C | 6.32 |
MYO4
|
One of two type V myosin motors (along with MYO2) involved in actin-based transport of cargos; required for mRNA transport, including ASH1 mRNA, and facilitating the growth and movement of ER tubules into the growing bud along with She3p |
|
YKL219W | 6.30 |
COS9
|
Protein of unknown function, member of the DUP380 subfamily of conserved, often subtelomerically-encoded proteins |
|
YCR087C-A | 6.28 |
LUG1
|
Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the nucleolus; YCR087C-A is not an essential gene |
|
YBR066C | 6.28 |
NRG2
|
Transcriptional repressor that mediates glucose repression and negatively regulates filamentous growth; has similarity to Nrg1p |
|
YBR023C | 6.24 |
CHS3
|
Chitin synthase III, catalyzes the transfer of N-acetylglucosamine (GlcNAc) to chitin; required for synthesis of the majority of cell wall chitin, the chitin ring during bud emergence, and spore wall chitosan |
|
YBR158W | 6.14 |
AMN1
|
Protein required for daughter cell separation, multiple mitotic checkpoints, and chromosome stability; contains 12 degenerate leucine-rich repeat motifs; expression is induced by the Mitotic Exit Network (MEN) |
|
YMR319C | 6.05 |
FET4
|
Low-affinity Fe(II) transporter of the plasma membrane |
|
YLR042C | 6.03 |
Protein of unknown function; localizes to the cytoplasm; YLL042C is not an essential gene |
||
YKR093W | 6.01 |
PTR2
|
Integral membrane peptide transporter, mediates transport of di- and tri-peptides; conserved protein that contains 12 transmembrane domains; PTR2 expression is regulated by the N-end rule pathway via repression by Cup9p |
|
YMR318C | 6.00 |
ADH6
|
NADPH-dependent medium chain alcohol dehydrogenase with broad substrate specificity; member of the cinnamyl family of alcohol dehydrogenases; may be involved in fusel alcohol synthesis or in aldehyde tolerance |
|
YPL037C | 5.99 |
EGD1
|
Subunit beta1 of the nascent polypeptide-associated complex (NAC) involved in protein targeting, associated with cytoplasmic ribosomes; enhances DNA binding of the Gal4p activator; homolog of human BTF3b |
|
YKL096W | 5.92 |
CWP1
|
Cell wall mannoprotein, linked to a beta-1,3- and beta-1,6-glucan heteropolymer through a phosphodiester bond; involved in cell wall organization |
|
YMR202W | 5.90 |
ERG2
|
C-8 sterol isomerase, catalyzes the isomerization of the delta-8 double bond to the delta-7 position at an intermediate step in ergosterol biosynthesis |
|
YKL068W-A | 5.89 |
Putative protein of unknown function; identified by homology to Ashbya gossypii |
||
YGL255W | 5.76 |
ZRT1
|
High-affinity zinc transporter of the plasma membrane, responsible for the majority of zinc uptake; transcription is induced under low-zinc conditions by the Zap1p transcription factor |
|
YDR257C | 5.72 |
SET7
|
Nuclear protein that contains a SET-domain, which have been shown to mediate methyltransferase activity in other proteins |
|
YJR069C | 5.69 |
HAM1
|
Conserved protein with deoxyribonucleoside triphosphate pyrophosphohydrolase activity, mediates exclusion of noncanonical purines from deoxyribonucleoside triphosphate pools; mutant is sensitive to the base analog 6-N-hydroxylaminopurine |
|
YIL158W | 5.68 |
AIM20
|
Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the vacuole; null mutant displays increased frequency of mitochondrial genome loss (petite formation) |
|
YHR063C | 5.63 |
PAN5
|
2-dehydropantoate 2-reductase, part of the pantothenic acid pathway, structurally homologous to E. coli panE |
|
YMR083W | 5.60 |
ADH3
|
Mitochondrial alcohol dehydrogenase isozyme III; involved in the shuttling of mitochondrial NADH to the cytosol under anaerobic conditions and ethanol production |
|
YNL162W | 5.59 |
RPL42A
|
Protein component of the large (60S) ribosomal subunit, identical to Rpl42Bp and has similarity to rat L44 ribosomal protein |
|
YOR153W | 5.55 |
PDR5
|
Plasma membrane ATP-binding cassette (ABC) transporter, short-lived multidrug transporter actively regulated by Pdr1p; also involved in steroid transport, cation resistance, and cellular detoxification during exponential growth |
|
YLR132C | 5.51 |
Protein of unknown function; green fluorescent protein (GFP)-tagged protein localizes to mitochondria and nucleus; YLR132C is an essential gene |
||
YKL119C | 5.49 |
VPH2
|
Integral membrane protein required for vacuolar H+-ATPase (V-ATPase) function, although not an actual component of the V-ATPase complex; functions in the assembly of the V-ATPase; localized to the endoplasmic reticulum (ER) |
|
YNR043W | 5.46 |
MVD1
|
Mevalonate pyrophosphate decarboxylase, essential enzyme involved in the biosynthesis of isoprenoids and sterols, including ergosterol; acts as a homodimer |
|
YHR063W-A | 5.44 |
Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data |
||
YGR242W | 5.43 |
Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified ORF YAP1802/YGR241C |
||
YBR252W | 5.39 |
DUT1
|
dUTPase, catalyzes hydrolysis of dUTP to dUMP and PPi, thereby preventing incorporation of uracil into DNA during replication; critical for the maintenance of genetic stability |
|
YLR285W | 5.36 |
NNT1
|
Putative nicotinamide N-methyltransferase, has a role in rDNA silencing and in lifespan determination |
|
YGR138C | 5.36 |
TPO2
|
Polyamine transport protein specific for spermine; localizes to the plasma membrane; transcription of TPO2 is regulated by Haa1p; member of the major facilitator superfamily |
|
YOL040C | 5.34 |
RPS15
|
Protein component of the small (40S) ribosomal subunit; has similarity to E. coli S19 and rat S15 ribosomal proteins |
|
YGR266W | 5.33 |
Protein of unknown function, predicted to contain a single transmembrane domain; localized to both the mitochondrial outer membrane and the plasma membrane |
||
YBR177C | 5.32 |
EHT1
|
Acyl-coenzymeA:ethanol O-acyltransferase that plays a minor role in medium-chain fatty acid ethyl ester biosynthesis; possesses short-chain esterase activity; localizes to lipid particles and the mitochondrial outer membrane |
|
YDR321W | 5.31 |
ASP1
|
Cytosolic L-asparaginase, involved in asparagine catabolism |
|
YML063W | 5.31 |
RPS1B
|
Ribosomal protein 10 (rp10) of the small (40S) subunit; nearly identical to Rps1Ap and has similarity to rat S3a ribosomal protein |
|
YMR177W | 5.31 |
MMT1
|
Putative metal transporter involved in mitochondrial iron accumulation; closely related to Mmt2p |
|
YER134C | 5.25 |
Putative protein of unknown function; non-essential gene |
||
YNL169C | 5.17 |
PSD1
|
Phosphatidylserine decarboxylase of the mitochondrial inner membrane, converts phosphatidylserine to phosphatidylethanolamine |
|
YPL263C | 5.15 |
KEL3
|
Cytoplasmic protein of unknown function |
|
YNL234W | 5.14 |
Similar to globins and has a functional heme-binding domain; involved in glucose signaling or metabolism; regulated by Rgt1p |
||
YDR032C | 5.10 |
PST2
|
Protein with similarity to members of a family of flavodoxin-like proteins; induced by oxidative stress in a Yap1p dependent manner; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies |
|
YMR082C | 5.09 |
Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data |
||
YOL085C | 5.08 |
Dubious open reading frame unlikely to encode a protein, based on experimental and comparative sequence data; partially overlaps the dubious gene YOL085W-A |
||
YMR208W | 5.07 |
ERG12
|
Mevalonate kinase, acts in the biosynthesis of isoprenoids and sterols, including ergosterol, from mevalonate |
|
YDR099W | 5.07 |
BMH2
|
14-3-3 protein, minor isoform; controls proteome at post-transcriptional level, binds proteins and DNA, involved in regulation of many processes including exocytosis, vesicle transport, Ras/MAPK signaling, and rapamycin-sensitive signaling |
|
YOR092W | 5.07 |
ECM3
|
Non-essential protein of unknown function; involved in signal transduction and the genotoxic response; induced rapidly in response to treatment with 8-methoxypsoralen and UVA irradiation |
|
YDR353W | 5.04 |
TRR1
|
Cytoplasmic thioredoxin reductase, key regulatory enzyme that determines the redox state of the thioredoxin system, which acts as a disulfide reductase system and protects cells against both oxidative and reductive stress |
|
YOL104C | 5.02 |
NDJ1
|
Meiosis-specific telomere protein, required for bouquet formation, effective homolog pairing, ordered cross-over distribution (interference), sister chromatid cohesion at meiotic telomeres, and segregation of small chromosomes |
|
YDL211C | 5.02 |
Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the vacuole |
||
YDR211W | 5.01 |
GCD6
|
Catalytic epsilon subunit of the translation initiation factor eIF2B, the guanine-nucleotide exchange factor for eIF2; activity subsequently regulated by phosphorylated eIF2; first identified as a negative regulator of GCN4 expression |
|
YOR342C | 4.97 |
Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and the nucleus |
||
YMR305C | 4.96 |
SCW10
|
Cell wall protein with similarity to glucanases; may play a role in conjugation during mating based on mutant phenotype and its regulation by Ste12p |
|
YKL153W | 4.94 |
Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; transcription of both YLK153W and the overlapping essential gene GPM1 is reduced in the gcr1 null mutant |
||
YMR320W | 4.92 |
Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data |
||
YOL124C | 4.91 |
TRM11
|
Catalytic subunit of an adoMet-dependent tRNA methyltransferase complex (Trm11p-Trm112p), required for the methylation of the guanosine nucleotide at position 10 (m2G10) in tRNAs; contains a THUMP domain and a methyltransferase domain |
|
YDL236W | 4.91 |
PHO13
|
Alkaline phosphatase specific for p-nitrophenyl phosphate, involved in dephosphorylation of histone II-A and casein |
|
YHR070C-A | 4.87 |
Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; overlaps the verified gene TRM5/YHR070W |
||
YGR241C | 4.86 |
YAP1802
|
Protein involved in clathrin cage assembly; binds Pan1p and clathrin; homologous to Yap1801p, member of the AP180 protein family |
|
YGL001C | 4.83 |
ERG26
|
C-3 sterol dehydrogenase, catalyzes the second of three steps required to remove two C-4 methyl groups from an intermediate in ergosterol biosynthesis |
|
YPR010C | 4.80 |
RPA135
|
RNA polymerase I subunit A135 |
|
YOL103W | 4.79 |
ITR2
|
Myo-inositol transporter with strong similarity to the major myo-inositol transporter Itr1p, member of the sugar transporter superfamily; expressed constitutively |
|
YPR060C | 4.76 |
ARO7
|
Chorismate mutase, catalyzes the conversion of chorismate to prephenate to initiate the tyrosine/phenylalanine-specific branch of aromatic amino acid biosynthesis |
|
YDR279W | 4.74 |
RNH202
|
Ribonuclease H2 subunit, required for RNase H2 activity |
|
YPL211W | 4.73 |
NIP7
|
Nucleolar protein required for 60S ribosome subunit biogenesis, constituent of 66S pre-ribosomal particles; physically interacts with Nop8p and the exosome subunit Rrp43p |
|
YKR003W | 4.73 |
OSH6
|
Member of an oxysterol-binding protein family with overlapping, redundant functions in sterol metabolism and which collectively perform a function essential for viability; GFP-fusion protein localizes to the cell periphery |
|
YBR210W | 4.73 |
ERV15
|
Protein involved in export of proteins from the endoplasmic reticulum, has similarity to Erv14p |
|
YOL136C | 4.70 |
PFK27
|
6-phosphofructo-2-kinase, catalyzes synthesis of fructose-2,6-bisphosphate; inhibited by phosphoenolpyruvate and sn-glycerol 3-phosphate, expression induced by glucose and sucrose, transcriptional regulation involves protein kinase A |
|
YMR012W | 4.70 |
CLU1
|
eIF3 component of unknown function; deletion causes defects in mitochondrial organization but not in growth or translation initiation, can rescue cytokinesis and mitochondrial organization defects of the Dictyostelium cluA- mutant |
|
YKL033W-A | 4.69 |
Putative protein of unknown function; similar to uncharacterized proteins from other fungi |
||
YDR072C | 4.68 |
IPT1
|
Inositolphosphotransferase 1, involved in synthesis of mannose-(inositol-P)2-ceramide (M(IP)2C), which is the most abundant sphingolipid in cells, mutation confers resistance to the antifungals syringomycin E and DmAMP1 in some growth media |
|
YLL024C | 4.65 |
SSA2
|
ATP binding protein involved in protein folding and vacuolar import of proteins; member of heat shock protein 70 (HSP70) family; associated with the chaperonin-containing T-complex; present in the cytoplasm, vacuolar membrane and cell wall |
|
YDR276C | 4.63 |
PMP3
|
Small plasma membrane protein related to a family of plant polypeptides that are overexpressed under high salt concentration or low temperature, not essential for viability, deletion causes hyperpolarization of the plasma membrane potential |
|
YMR003W | 4.62 |
AIM34
|
Protein of unknown function; GFP-fusion protein localizes to the mitochondria; null mutant is viable and displays decreased frequency of mitochondrial genome loss (petite formation) and severe growth defect in minimal glycerol media |
|
YNL028W | 4.61 |
Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data |
||
YIL162W | 4.60 |
SUC2
|
Invertase, sucrose hydrolyzing enzyme; a secreted, glycosylated form is regulated by glucose repression, and an intracellular, nonglycosylated enzyme is produced constitutively |
|
YIR020C | 4.55 |
Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data |
||
YDR517W | 4.54 |
GRH1
|
Acetylated, cis-golgi localized protein involved in ER to Golgi transport; homolog of human GRASP65; forms a complex with the coiled-coil protein Bug1p; mutants are compromised for the fusion of ER-derived vesicles with Golgi membranes |
|
YOR087W | 4.53 |
YVC1
|
Vacuolar cation channel, mediates release of Ca(2+) from the vacuole in response to hyperosmotic shock |
|
YHR010W | 4.52 |
RPL27A
|
Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl27Bp and has similarity to rat L27 ribosomal protein |
|
YEL001C | 4.52 |
IRC22
|
Putative protein of unknown function; green fluorescent protein (GFP)-fusion localizes to the ER; YEL001C is non-essential; null mutant displays increased levels of spontaneous Rad52p foci |
|
YFL017C | 4.51 |
GNA1
|
Evolutionarily conserved glucosamine-6-phosphate acetyltransferase required for multiple cell cycle events including passage through START, DNA synthesis, and mitosis; involved in UDP-N-acetylglucosamine synthesis, forms GlcNAc6P from AcCoA |
|
YNL044W | 4.45 |
YIP3
|
Protein localized to COPII vesicles, proposed to be involved in ER to Golgi transport; interacts with members of the Rab GTPase family and Yip1p; also interacts with Rtn1p |
|
YHR108W | 4.43 |
GGA2
|
Golgi-localized protein with homology to gamma-adaptin, interacts with and regulates Arf1p and Arf2p in a GTP-dependent manner in order to facilitate traffic through the late Golgi |
|
YER056C-A | 4.41 |
RPL34A
|
Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl34Bp and has similarity to rat L34 ribosomal protein |
|
YPR033C | 4.40 |
HTS1
|
Cytoplasmic and mitochondrial histidine tRNA synthetase; encoded by a single nuclear gene that specifies two messages; efficient mitochondrial localization requires both a presequence and an amino-terminal sequence |
|
YFR025C | 4.38 |
HIS2
|
Histidinolphosphatase, catalyzes the eighth step in histidine biosynthesis; mutations cause histidine auxotrophy and sensitivity to Cu, Co, and Ni salts; transcription is regulated by general amino acid control |
|
YGR177C | 4.38 |
ATF2
|
Alcohol acetyltransferase, may play a role in steroid detoxification; forms volatile esters during fermentation, which is important in brewing |
|
YHL028W | 4.34 |
WSC4
|
ER membrane protein involved in the translocation of soluble secretory proteins and insertion of membrane proteins into the ER membrane; may also have a role in the stress response but has only partial functional overlap with WSC1-3 |
|
YIL118W | 4.34 |
RHO3
|
Non-essential small GTPase of the Rho/Rac subfamily of Ras-like proteins involved in the establishment of cell polarity; GTPase activity positively regulated by the GTPase activating protein (GAP) Rgd1p |
|
YLR089C | 4.34 |
ALT1
|
Putative alanine transaminase (glutamic pyruvic transaminase); the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies |
|
YAL023C | 4.33 |
PMT2
|
Protein O-mannosyltransferase, transfers mannose residues from dolichyl phosphate-D-mannose to protein serine/threonine residues; acts in a complex with Pmt1p, can instead interact with Pmt5p in some conditions; target for new antifungals |
|
YLR428C | 4.33 |
Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified ORF CRN1 |
||
YCL036W | 4.32 |
GFD2
|
Protein of unknown function, identified as a high-copy suppressor of a dbp5 mutation |
|
YOR108C-A | 4.32 |
Identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching |
||
YER001W | 4.31 |
MNN1
|
Alpha-1,3-mannosyltransferase, integral membrane glycoprotein of the Golgi complex, required for addition of alpha1,3-mannose linkages to N-linked and O-linked oligosaccharides, one of five S. cerevisiae proteins of the MNN1 family |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
12.7 | 38.0 | GO:0000098 | sulfur amino acid catabolic process(GO:0000098) |
8.6 | 34.5 | GO:0046500 | S-adenosylmethionine metabolic process(GO:0046500) |
6.0 | 42.3 | GO:0010696 | positive regulation of spindle pole body separation(GO:0010696) |
4.9 | 34.3 | GO:0046501 | protoporphyrinogen IX biosynthetic process(GO:0006782) protoporphyrinogen IX metabolic process(GO:0046501) |
4.8 | 14.4 | GO:0009094 | tyrosine biosynthetic process(GO:0006571) L-phenylalanine biosynthetic process(GO:0009094) erythrose 4-phosphate/phosphoenolpyruvate family amino acid biosynthetic process(GO:1902223) |
4.2 | 12.7 | GO:0009176 | deoxyribonucleoside monophosphate biosynthetic process(GO:0009157) deoxyribonucleoside monophosphate metabolic process(GO:0009162) pyrimidine deoxyribonucleoside monophosphate metabolic process(GO:0009176) pyrimidine deoxyribonucleoside monophosphate biosynthetic process(GO:0009177) |
4.0 | 12.0 | GO:0044209 | AMP salvage(GO:0044209) |
3.9 | 19.4 | GO:0009051 | pentose-phosphate shunt, oxidative branch(GO:0009051) |
3.8 | 7.5 | GO:0046083 | adenine metabolic process(GO:0046083) |
3.5 | 17.7 | GO:0006177 | GMP biosynthetic process(GO:0006177) |
3.5 | 10.4 | GO:0007189 | adenylate cyclase-activating G-protein coupled receptor signaling pathway(GO:0007189) |
3.4 | 13.7 | GO:0046490 | isopentenyl diphosphate biosynthetic process(GO:0009240) isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287) isopentenyl diphosphate metabolic process(GO:0046490) |
3.1 | 9.4 | GO:0009298 | GDP-mannose biosynthetic process(GO:0009298) GDP-mannose metabolic process(GO:0019673) |
3.1 | 12.5 | GO:0046898 | response to organic cyclic compound(GO:0014070) response to cycloheximide(GO:0046898) |
3.0 | 11.8 | GO:0000296 | spermine transport(GO:0000296) |
2.8 | 5.7 | GO:0009211 | pyrimidine deoxyribonucleoside triphosphate metabolic process(GO:0009211) |
2.7 | 16.5 | GO:0006646 | phosphatidylethanolamine biosynthetic process(GO:0006646) |
2.7 | 2.7 | GO:0046037 | GMP metabolic process(GO:0046037) |
2.7 | 8.0 | GO:0006798 | polyphosphate catabolic process(GO:0006798) |
2.7 | 2.7 | GO:0019413 | acetate biosynthetic process(GO:0019413) |
2.5 | 29.5 | GO:0000917 | barrier septum assembly(GO:0000917) cell septum assembly(GO:0090529) |
2.4 | 7.1 | GO:0072361 | regulation of glycolytic process by regulation of transcription from RNA polymerase II promoter(GO:0072361) regulation of glycolytic process by positive regulation of transcription from RNA polymerase II promoter(GO:0072363) |
2.4 | 7.1 | GO:1900101 | regulation of endoplasmic reticulum unfolded protein response(GO:1900101) |
2.3 | 9.3 | GO:0030497 | fatty acid elongation(GO:0030497) |
2.3 | 11.3 | GO:0035434 | copper ion transmembrane transport(GO:0035434) |
2.3 | 4.5 | GO:0009226 | nucleotide-sugar biosynthetic process(GO:0009226) |
2.2 | 9.0 | GO:0006528 | asparagine metabolic process(GO:0006528) |
2.2 | 8.7 | GO:0098610 | agglutination involved in conjugation with cellular fusion(GO:0000752) agglutination involved in conjugation(GO:0000771) heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157) cell-cell adhesion(GO:0098609) adhesion between unicellular organisms(GO:0098610) multi organism cell adhesion(GO:0098740) cell-cell adhesion via plasma-membrane adhesion molecules(GO:0098742) |
2.1 | 10.7 | GO:0046655 | folic acid metabolic process(GO:0046655) folic acid biosynthetic process(GO:0046656) |
2.1 | 18.5 | GO:0070525 | tRNA threonylcarbamoyladenosine metabolic process(GO:0070525) |
2.0 | 14.3 | GO:0005992 | trehalose biosynthetic process(GO:0005992) oligosaccharide biosynthetic process(GO:0009312) disaccharide biosynthetic process(GO:0046351) |
2.0 | 4.1 | GO:0006110 | regulation of glycolytic process(GO:0006110) |
2.0 | 6.0 | GO:0015680 | intracellular copper ion transport(GO:0015680) |
2.0 | 68.5 | GO:0006418 | tRNA aminoacylation for protein translation(GO:0006418) |
1.9 | 9.6 | GO:0051083 | 'de novo' cotranslational protein folding(GO:0051083) |
1.9 | 7.6 | GO:0070072 | proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072) |
1.9 | 5.6 | GO:0051439 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle(GO:0051436) regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle(GO:0051439) negative regulation of ubiquitin protein ligase activity(GO:1904667) |
1.9 | 13.1 | GO:0000372 | Group I intron splicing(GO:0000372) RNA splicing, via transesterification reactions with guanosine as nucleophile(GO:0000376) |
1.8 | 23.6 | GO:0009636 | response to toxic substance(GO:0009636) |
1.7 | 5.2 | GO:0034356 | NAD biosynthesis via nicotinamide riboside salvage pathway(GO:0034356) |
1.7 | 5.1 | GO:0031384 | regulation of initiation of mating projection growth(GO:0031384) |
1.7 | 22.0 | GO:0030011 | maintenance of cell polarity(GO:0030011) |
1.7 | 6.7 | GO:0045141 | meiotic telomere clustering(GO:0045141) establishment of chromosome localization(GO:0051303) chromosome localization to nuclear envelope involved in homologous chromosome segregation(GO:0090220) |
1.7 | 30.1 | GO:0006407 | rRNA export from nucleus(GO:0006407) rRNA transport(GO:0051029) |
1.6 | 14.8 | GO:0000947 | amino acid catabolic process to alcohol via Ehrlich pathway(GO:0000947) |
1.6 | 9.7 | GO:0007030 | Golgi organization(GO:0007030) |
1.5 | 7.7 | GO:0001676 | long-chain fatty acid metabolic process(GO:0001676) |
1.5 | 12.3 | GO:0015940 | pantothenate metabolic process(GO:0015939) pantothenate biosynthetic process(GO:0015940) |
1.4 | 2.9 | GO:0000461 | endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000461) |
1.4 | 4.3 | GO:0090338 | regulation of formin-nucleated actin cable assembly(GO:0090337) positive regulation of formin-nucleated actin cable assembly(GO:0090338) |
1.4 | 5.7 | GO:0050667 | homocysteine metabolic process(GO:0050667) |
1.4 | 2.8 | GO:0006531 | aspartate metabolic process(GO:0006531) |
1.4 | 5.6 | GO:0070588 | calcium ion transmembrane transport(GO:0070588) |
1.4 | 19.6 | GO:0006037 | cell wall chitin metabolic process(GO:0006037) |
1.3 | 5.1 | GO:0051457 | maintenance of protein location in nucleus(GO:0051457) |
1.3 | 15.3 | GO:0051156 | glucose 6-phosphate metabolic process(GO:0051156) |
1.3 | 6.3 | GO:0043433 | negative regulation of sequence-specific DNA binding transcription factor activity(GO:0043433) |
1.2 | 10.7 | GO:0006384 | transcription initiation from RNA polymerase III promoter(GO:0006384) |
1.2 | 2.4 | GO:0042992 | regulation of transcription factor import into nucleus(GO:0042990) negative regulation of transcription factor import into nucleus(GO:0042992) |
1.2 | 9.4 | GO:0042219 | cellular modified amino acid catabolic process(GO:0042219) |
1.2 | 8.1 | GO:0019509 | L-methionine biosynthetic process from methylthioadenosine(GO:0019509) amino acid salvage(GO:0043102) L-methionine biosynthetic process(GO:0071265) L-methionine salvage(GO:0071267) |
1.1 | 8.0 | GO:0006797 | polyphosphate metabolic process(GO:0006797) |
1.1 | 2.2 | GO:0009186 | deoxyribonucleoside diphosphate metabolic process(GO:0009186) |
1.1 | 3.2 | GO:0043171 | peptide catabolic process(GO:0043171) |
1.1 | 5.4 | GO:0042401 | tryptophan biosynthetic process(GO:0000162) amine biosynthetic process(GO:0009309) cellular biogenic amine biosynthetic process(GO:0042401) indole-containing compound biosynthetic process(GO:0042435) indolalkylamine biosynthetic process(GO:0046219) |
1.1 | 4.3 | GO:0034473 | U1 snRNA 3'-end processing(GO:0034473) |
1.1 | 4.3 | GO:0008299 | isoprenoid metabolic process(GO:0006720) isoprenoid biosynthetic process(GO:0008299) |
1.1 | 141.6 | GO:0002181 | cytoplasmic translation(GO:0002181) |
1.0 | 6.2 | GO:0072337 | modified amino acid transport(GO:0072337) |
1.0 | 2.0 | GO:0070637 | nicotinamide riboside metabolic process(GO:0046495) pyridine nucleoside metabolic process(GO:0070637) |
1.0 | 9.0 | GO:0009435 | NAD biosynthetic process(GO:0009435) |
1.0 | 3.9 | GO:1900434 | filamentous growth of a population of unicellular organisms in response to starvation(GO:0036170) regulation of filamentous growth of a population of unicellular organisms in response to starvation(GO:1900434) positive regulation of filamentous growth of a population of unicellular organisms in response to starvation(GO:1900436) |
1.0 | 1.9 | GO:0061418 | regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061418) |
1.0 | 6.8 | GO:0040031 | snRNA pseudouridine synthesis(GO:0031120) snRNA modification(GO:0040031) |
1.0 | 1.9 | GO:0006688 | glycosphingolipid metabolic process(GO:0006687) glycosphingolipid biosynthetic process(GO:0006688) |
1.0 | 6.7 | GO:0043137 | DNA replication, removal of RNA primer(GO:0043137) |
0.9 | 5.7 | GO:0090158 | regulation of phosphatidylinositol dephosphorylation(GO:0060304) endoplasmic reticulum membrane organization(GO:0090158) |
0.9 | 4.7 | GO:0006673 | inositolphosphoceramide metabolic process(GO:0006673) |
0.9 | 7.3 | GO:0006616 | SRP-dependent cotranslational protein targeting to membrane, translocation(GO:0006616) |
0.9 | 20.0 | GO:0097384 | ergosterol biosynthetic process(GO:0006696) phytosteroid biosynthetic process(GO:0016129) cellular alcohol biosynthetic process(GO:0044108) cellular lipid biosynthetic process(GO:0097384) |
0.9 | 3.6 | GO:0007050 | cell cycle arrest(GO:0007050) |
0.9 | 7.1 | GO:0048309 | endoplasmic reticulum inheritance(GO:0048309) |
0.9 | 2.6 | GO:2000879 | regulation of oligopeptide transport by regulation of transcription from RNA polymerase II promoter(GO:0035950) negative regulation of oligopeptide transport by negative regulation of transcription from RNA polymerase II promoter(GO:0035952) regulation of dipeptide transport by regulation of transcription from RNA polymerase II promoter(GO:0035953) negative regulation of dipeptide transport by negative regulation of transcription from RNA polymerase II promoter(GO:0035955) negative regulation of oligopeptide transport(GO:2000877) negative regulation of dipeptide transport(GO:2000879) |
0.9 | 2.6 | GO:0045901 | positive regulation of translational elongation(GO:0045901) |
0.8 | 5.8 | GO:0030847 | termination of RNA polymerase II transcription, exosome-dependent(GO:0030847) |
0.8 | 2.5 | GO:0046416 | D-amino acid metabolic process(GO:0046416) |
0.8 | 2.5 | GO:0016114 | terpenoid metabolic process(GO:0006721) terpenoid biosynthetic process(GO:0016114) farnesyl diphosphate biosynthetic process(GO:0045337) farnesyl diphosphate metabolic process(GO:0045338) |
0.8 | 1.6 | GO:0071478 | cellular response to radiation(GO:0071478) cellular response to light stimulus(GO:0071482) |
0.8 | 4.1 | GO:0009092 | homoserine metabolic process(GO:0009092) |
0.8 | 24.3 | GO:0006879 | cellular iron ion homeostasis(GO:0006879) |
0.8 | 3.2 | GO:0042938 | dipeptide transport(GO:0042938) |
0.8 | 4.0 | GO:0042780 | tRNA 3'-end processing(GO:0042780) |
0.8 | 4.0 | GO:0006491 | N-glycan processing(GO:0006491) |
0.8 | 1.6 | GO:0015786 | pyrimidine nucleotide-sugar transport(GO:0015781) UDP-glucose transport(GO:0015786) |
0.8 | 3.9 | GO:0044070 | regulation of anion transport(GO:0044070) |
0.8 | 11.6 | GO:0015918 | sterol transport(GO:0015918) |
0.8 | 3.1 | GO:0030030 | cell projection organization(GO:0030030) cell projection assembly(GO:0030031) |
0.7 | 8.1 | GO:0007109 | obsolete cytokinesis, completion of separation(GO:0007109) |
0.7 | 21.3 | GO:0006414 | translational elongation(GO:0006414) |
0.7 | 2.2 | GO:0030846 | termination of RNA polymerase II transcription, poly(A)-coupled(GO:0030846) |
0.7 | 3.6 | GO:0031119 | tRNA pseudouridine synthesis(GO:0031119) |
0.7 | 2.2 | GO:0060988 | lipid tube assembly(GO:0060988) protein-lipid complex assembly(GO:0065005) protein-lipid complex subunit organization(GO:0071825) |
0.7 | 1.4 | GO:0031032 | assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin structure organization(GO:0031032) actomyosin contractile ring organization(GO:0044837) |
0.7 | 3.5 | GO:0031087 | deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087) |
0.7 | 6.9 | GO:0015988 | energy coupled proton transmembrane transport, against electrochemical gradient(GO:0015988) ATP hydrolysis coupled proton transport(GO:0015991) ATP hydrolysis coupled transmembrane transport(GO:0090662) |
0.7 | 2.7 | GO:0006857 | oligopeptide transport(GO:0006857) |
0.7 | 2.1 | GO:0046466 | sphingolipid catabolic process(GO:0030149) membrane lipid catabolic process(GO:0046466) |
0.7 | 0.7 | GO:0070592 | cell wall polysaccharide biosynthetic process(GO:0070592) |
0.7 | 3.4 | GO:0000028 | ribosomal small subunit assembly(GO:0000028) |
0.7 | 11.5 | GO:0042790 | transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:0042790) |
0.7 | 2.7 | GO:0009371 | positive regulation of transcription from RNA polymerase II promoter by pheromones(GO:0007329) positive regulation of transcription by pheromones(GO:0009371) |
0.7 | 3.3 | GO:0006564 | L-serine biosynthetic process(GO:0006564) |
0.7 | 16.7 | GO:1904029 | regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079) regulation of cyclin-dependent protein kinase activity(GO:1904029) |
0.7 | 2.0 | GO:0055078 | cellular sodium ion homeostasis(GO:0006883) sodium ion homeostasis(GO:0055078) |
0.6 | 1.3 | GO:0006023 | aminoglycan biosynthetic process(GO:0006023) chitin biosynthetic process(GO:0006031) glucosamine-containing compound biosynthetic process(GO:1901073) |
0.6 | 1.3 | GO:0010672 | regulation of transcription from RNA polymerase II promoter involved in meiotic cell cycle(GO:0010672) negative regulation of transcription from RNA polymerase II promoter involved in meiotic cell cycle(GO:0010674) |
0.6 | 4.4 | GO:0015791 | polyol transport(GO:0015791) |
0.6 | 1.9 | GO:0031532 | actin filament reorganization involved in cell cycle(GO:0030037) actin cytoskeleton reorganization(GO:0031532) actin filament reorganization(GO:0090527) |
0.6 | 5.0 | GO:0006829 | zinc II ion transport(GO:0006829) |
0.6 | 5.5 | GO:0032120 | ascospore-type prospore membrane assembly(GO:0032120) membrane biogenesis(GO:0044091) membrane assembly(GO:0071709) |
0.6 | 1.2 | GO:0016320 | endoplasmic reticulum membrane fusion(GO:0016320) |
0.6 | 1.8 | GO:0048194 | Golgi vesicle budding(GO:0048194) |
0.6 | 3.0 | GO:0006662 | glycerol ether metabolic process(GO:0006662) ether metabolic process(GO:0018904) |
0.6 | 3.0 | GO:0036228 | protein targeting to nuclear inner membrane(GO:0036228) |
0.6 | 1.8 | GO:0019419 | sulfate assimilation, phosphoadenylyl sulfate reduction by phosphoadenylyl-sulfate reductase (thioredoxin)(GO:0019379) sulfate reduction(GO:0019419) |
0.6 | 3.4 | GO:0030042 | actin filament depolymerization(GO:0030042) |
0.6 | 2.8 | GO:0043555 | regulation of translation in response to stress(GO:0043555) |
0.6 | 1.1 | GO:0031684 | heterotrimeric G-protein complex cycle(GO:0031684) |
0.6 | 2.8 | GO:0000743 | nuclear migration involved in conjugation with cellular fusion(GO:0000743) |
0.6 | 7.2 | GO:0007120 | axial cellular bud site selection(GO:0007120) |
0.5 | 2.1 | GO:0051446 | positive regulation of meiotic nuclear division(GO:0045836) positive regulation of meiotic cell cycle(GO:0051446) |
0.5 | 9.6 | GO:0030488 | tRNA methylation(GO:0030488) |
0.5 | 2.1 | GO:0015886 | heme transport(GO:0015886) |
0.5 | 3.1 | GO:0034729 | histone H3-K79 methylation(GO:0034729) |
0.5 | 2.1 | GO:0032262 | pyrimidine ribonucleotide salvage(GO:0010138) pyrimidine nucleotide salvage(GO:0032262) pyrimidine nucleoside salvage(GO:0043097) UMP salvage(GO:0044206) |
0.5 | 1.0 | GO:0031292 | gene conversion at mating-type locus, DNA double-strand break processing(GO:0031292) |
0.5 | 6.2 | GO:0006555 | methionine metabolic process(GO:0006555) |
0.5 | 7.1 | GO:0018208 | protein peptidyl-prolyl isomerization(GO:0000413) peptidyl-proline modification(GO:0018208) |
0.5 | 1.0 | GO:0018023 | peptidyl-lysine trimethylation(GO:0018023) |
0.5 | 3.5 | GO:0043328 | protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328) |
0.5 | 8.3 | GO:0006446 | regulation of translational initiation(GO:0006446) |
0.5 | 4.4 | GO:0000105 | histidine biosynthetic process(GO:0000105) histidine metabolic process(GO:0006547) imidazole-containing compound metabolic process(GO:0052803) |
0.5 | 1.5 | GO:0015693 | magnesium ion transport(GO:0015693) |
0.5 | 2.9 | GO:0006621 | protein retention in ER lumen(GO:0006621) maintenance of protein localization in endoplasmic reticulum(GO:0035437) |
0.5 | 1.0 | GO:0043065 | positive regulation of cell death(GO:0010942) positive regulation of apoptotic process(GO:0043065) positive regulation of programmed cell death(GO:0043068) |
0.5 | 2.3 | GO:0006551 | leucine metabolic process(GO:0006551) leucine biosynthetic process(GO:0009098) |
0.5 | 4.7 | GO:0031365 | N-terminal protein amino acid modification(GO:0031365) |
0.5 | 1.4 | GO:0010978 | gene silencing involved in chronological cell aging(GO:0010978) gene silencing by RNA(GO:0031047) |
0.5 | 2.3 | GO:0007535 | donor selection(GO:0007535) |
0.5 | 3.2 | GO:0000056 | ribosomal small subunit export from nucleus(GO:0000056) |
0.4 | 2.7 | GO:0051231 | mitotic spindle elongation(GO:0000022) spindle elongation(GO:0051231) |
0.4 | 1.3 | GO:0071462 | response to water(GO:0009415) cellular response to water stimulus(GO:0071462) |
0.4 | 0.9 | GO:0015780 | nucleotide-sugar transport(GO:0015780) |
0.4 | 0.9 | GO:0009088 | threonine biosynthetic process(GO:0009088) |
0.4 | 2.1 | GO:0016126 | steroid biosynthetic process(GO:0006694) sterol biosynthetic process(GO:0016126) |
0.4 | 1.7 | GO:0070911 | global genome nucleotide-excision repair(GO:0070911) |
0.4 | 0.8 | GO:0035494 | SNARE complex disassembly(GO:0035494) |
0.4 | 0.8 | GO:0090069 | negative regulation of DNA-templated transcription, elongation(GO:0032785) regulation of ribosome biogenesis(GO:0090069) regulation of rRNA processing(GO:2000232) |
0.4 | 1.7 | GO:0015809 | arginine transport(GO:0015809) |
0.4 | 1.2 | GO:0015867 | ATP transport(GO:0015867) |
0.4 | 8.2 | GO:0008219 | apoptotic process(GO:0006915) cell death(GO:0008219) programmed cell death(GO:0012501) |
0.4 | 1.6 | GO:0016036 | cellular response to phosphate starvation(GO:0016036) |
0.4 | 0.8 | GO:0000101 | sulfur amino acid transport(GO:0000101) |
0.4 | 1.2 | GO:0000092 | mitotic anaphase B(GO:0000092) |
0.4 | 3.6 | GO:0045053 | protein retention in Golgi apparatus(GO:0045053) |
0.4 | 8.7 | GO:0000027 | ribosomal large subunit assembly(GO:0000027) |
0.4 | 1.6 | GO:0006778 | porphyrin-containing compound metabolic process(GO:0006778) porphyrin-containing compound biosynthetic process(GO:0006779) heme biosynthetic process(GO:0006783) tetrapyrrole metabolic process(GO:0033013) tetrapyrrole biosynthetic process(GO:0033014) heme metabolic process(GO:0042168) |
0.4 | 3.0 | GO:0005987 | sucrose metabolic process(GO:0005985) sucrose catabolic process(GO:0005987) |
0.4 | 0.7 | GO:0045048 | protein insertion into ER membrane(GO:0045048) |
0.4 | 1.5 | GO:0051126 | negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316) negative regulation of actin nucleation(GO:0051126) |
0.4 | 1.1 | GO:0007121 | bipolar cellular bud site selection(GO:0007121) |
0.4 | 0.7 | GO:0034198 | regulation of TOR signaling(GO:0032006) cellular response to amino acid starvation(GO:0034198) |
0.4 | 10.8 | GO:0006487 | protein N-linked glycosylation(GO:0006487) |
0.4 | 0.4 | GO:0071041 | antisense RNA transcript catabolic process(GO:0071041) |
0.3 | 55.5 | GO:0006364 | rRNA processing(GO:0006364) |
0.3 | 0.3 | GO:0000916 | actomyosin contractile ring contraction(GO:0000916) contractile ring contraction(GO:0036213) |
0.3 | 2.4 | GO:0009306 | protein secretion(GO:0009306) |
0.3 | 1.7 | GO:0046391 | 5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391) |
0.3 | 6.1 | GO:0000055 | ribosomal large subunit export from nucleus(GO:0000055) |
0.3 | 1.0 | GO:0006269 | DNA replication, synthesis of RNA primer(GO:0006269) |
0.3 | 5.4 | GO:0032508 | DNA duplex unwinding(GO:0032508) |
0.3 | 2.6 | GO:0006189 | 'de novo' IMP biosynthetic process(GO:0006189) |
0.3 | 1.6 | GO:0006617 | SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition(GO:0006617) |
0.3 | 0.6 | GO:1905038 | regulation of sphingolipid biosynthetic process(GO:0090153) negative regulation of sphingolipid biosynthetic process(GO:0090155) regulation of membrane lipid metabolic process(GO:1905038) |
0.3 | 4.1 | GO:0001100 | negative regulation of exit from mitosis(GO:0001100) |
0.3 | 0.9 | GO:0015677 | copper ion import(GO:0015677) |
0.3 | 0.9 | GO:0048279 | vesicle fusion with endoplasmic reticulum(GO:0048279) |
0.3 | 1.5 | GO:0031081 | nuclear pore distribution(GO:0031081) nuclear pore localization(GO:0051664) |
0.3 | 3.6 | GO:0006999 | nuclear pore organization(GO:0006999) |
0.3 | 1.2 | GO:0015883 | FAD transport(GO:0015883) |
0.3 | 0.6 | GO:0006658 | phosphatidylserine metabolic process(GO:0006658) |
0.3 | 2.3 | GO:0006734 | NADH metabolic process(GO:0006734) |
0.3 | 1.4 | GO:1901985 | positive regulation of histone acetylation(GO:0035066) positive regulation of protein acetylation(GO:1901985) positive regulation of peptidyl-lysine acetylation(GO:2000758) |
0.3 | 3.1 | GO:0051568 | histone H3-K4 methylation(GO:0051568) |
0.3 | 0.8 | GO:0008272 | sulfate transport(GO:0008272) |
0.3 | 0.8 | GO:0090110 | cargo loading into vesicle(GO:0035459) cargo loading into COPII-coated vesicle(GO:0090110) |
0.3 | 0.3 | GO:0036265 | RNA (guanine-N7)-methylation(GO:0036265) |
0.3 | 1.1 | GO:0006021 | inositol biosynthetic process(GO:0006021) |
0.3 | 1.6 | GO:0070096 | mitochondrial outer membrane translocase complex assembly(GO:0070096) |
0.3 | 0.5 | GO:0001927 | exocyst assembly(GO:0001927) |
0.3 | 7.2 | GO:0006612 | protein targeting to membrane(GO:0006612) |
0.3 | 1.6 | GO:0009130 | 'de novo' pyrimidine nucleobase biosynthetic process(GO:0006207) UMP biosynthetic process(GO:0006222) pyrimidine nucleoside monophosphate metabolic process(GO:0009129) pyrimidine nucleoside monophosphate biosynthetic process(GO:0009130) pyrimidine ribonucleoside monophosphate metabolic process(GO:0009173) pyrimidine ribonucleoside monophosphate biosynthetic process(GO:0009174) 'de novo' UMP biosynthetic process(GO:0044205) UMP metabolic process(GO:0046049) |
0.3 | 1.0 | GO:0055129 | L-proline biosynthetic process(GO:0055129) |
0.3 | 3.4 | GO:0000184 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184) |
0.3 | 0.8 | GO:1901977 | regulation of cell cycle checkpoint(GO:1901976) negative regulation of cell cycle checkpoint(GO:1901977) regulation of DNA damage checkpoint(GO:2000001) negative regulation of DNA damage checkpoint(GO:2000002) negative regulation of response to DNA damage stimulus(GO:2001021) |
0.3 | 2.0 | GO:0046856 | phosphatidylinositol dephosphorylation(GO:0046856) |
0.3 | 2.0 | GO:0006490 | oligosaccharide-lipid intermediate biosynthetic process(GO:0006490) |
0.2 | 1.5 | GO:0042991 | transcription factor import into nucleus(GO:0042991) |
0.2 | 0.5 | GO:0008612 | peptidyl-lysine modification to peptidyl-hypusine(GO:0008612) |
0.2 | 1.6 | GO:0046470 | phosphatidylcholine metabolic process(GO:0046470) |
0.2 | 3.2 | GO:0010499 | proteasomal ubiquitin-independent protein catabolic process(GO:0010499) |
0.2 | 3.1 | GO:0045324 | late endosome to vacuole transport(GO:0045324) |
0.2 | 1.1 | GO:0016255 | attachment of GPI anchor to protein(GO:0016255) |
0.2 | 12.5 | GO:0006888 | ER to Golgi vesicle-mediated transport(GO:0006888) |
0.2 | 1.2 | GO:0006855 | drug transmembrane transport(GO:0006855) |
0.2 | 2.6 | GO:0030148 | sphingolipid biosynthetic process(GO:0030148) |
0.2 | 0.6 | GO:0019748 | secondary metabolic process(GO:0019748) |
0.2 | 0.6 | GO:0046174 | alditol catabolic process(GO:0019405) glycerol catabolic process(GO:0019563) polyol catabolic process(GO:0046174) |
0.2 | 0.8 | GO:0031134 | sister chromatid biorientation(GO:0031134) |
0.2 | 0.6 | GO:0038032 | termination of signal transduction(GO:0023021) termination of G-protein coupled receptor signaling pathway(GO:0038032) |
0.2 | 1.2 | GO:0016125 | steroid metabolic process(GO:0008202) sterol metabolic process(GO:0016125) |
0.2 | 1.0 | GO:0043457 | regulation of cellular respiration(GO:0043457) |
0.2 | 0.4 | GO:0051320 | mitotic S phase(GO:0000084) S phase(GO:0051320) |
0.2 | 3.5 | GO:0009247 | glycolipid biosynthetic process(GO:0009247) |
0.2 | 1.5 | GO:0045039 | protein import into mitochondrial inner membrane(GO:0045039) |
0.2 | 0.4 | GO:0051666 | actin cortical patch localization(GO:0051666) |
0.2 | 8.0 | GO:0016311 | dephosphorylation(GO:0016311) |
0.2 | 1.3 | GO:0006415 | translational termination(GO:0006415) |
0.2 | 11.4 | GO:0006897 | endocytosis(GO:0006897) |
0.2 | 0.9 | GO:0000011 | vacuole inheritance(GO:0000011) |
0.2 | 0.8 | GO:0006890 | retrograde vesicle-mediated transport, Golgi to ER(GO:0006890) |
0.2 | 5.4 | GO:0006896 | Golgi to vacuole transport(GO:0006896) |
0.2 | 1.6 | GO:0006356 | regulation of transcription from RNA polymerase I promoter(GO:0006356) |
0.2 | 0.9 | GO:0006828 | manganese ion transport(GO:0006828) |
0.2 | 2.1 | GO:0001300 | chronological cell aging(GO:0001300) |
0.1 | 1.0 | GO:0007323 | peptide pheromone maturation(GO:0007323) |
0.1 | 0.6 | GO:0043489 | RNA stabilization(GO:0043489) mRNA stabilization(GO:0048255) |
0.1 | 0.3 | GO:0031990 | mRNA export from nucleus in response to heat stress(GO:0031990) regulation of protein desumoylation(GO:0060188) |
0.1 | 0.5 | GO:0006086 | acetyl-CoA biosynthetic process from pyruvate(GO:0006086) |
0.1 | 0.7 | GO:0034314 | Arp2/3 complex-mediated actin nucleation(GO:0034314) |
0.1 | 4.0 | GO:0072524 | pyridine-containing compound metabolic process(GO:0072524) |
0.1 | 0.5 | GO:0006661 | phosphatidylinositol biosynthetic process(GO:0006661) |
0.1 | 0.3 | GO:0051781 | positive regulation of cell division(GO:0051781) |
0.1 | 1.0 | GO:0006012 | galactose metabolic process(GO:0006012) |
0.1 | 0.6 | GO:0016560 | protein import into peroxisome matrix, docking(GO:0016560) protein to membrane docking(GO:0022615) |
0.1 | 0.2 | GO:0018342 | protein prenylation(GO:0018342) prenylation(GO:0097354) |
0.1 | 0.3 | GO:0071431 | tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431) |
0.1 | 1.1 | GO:0006272 | leading strand elongation(GO:0006272) |
0.1 | 1.8 | GO:0070085 | protein glycosylation(GO:0006486) macromolecule glycosylation(GO:0043413) glycosylation(GO:0070085) |
0.1 | 0.7 | GO:0006814 | sodium ion transport(GO:0006814) |
0.1 | 1.3 | GO:0007231 | osmosensory signaling pathway(GO:0007231) |
0.1 | 1.0 | GO:0031146 | SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146) |
0.1 | 0.1 | GO:0042439 | ethanolamine-containing compound metabolic process(GO:0042439) |
0.1 | 0.4 | GO:0097035 | lipid translocation(GO:0034204) regulation of membrane lipid distribution(GO:0097035) |
0.1 | 0.4 | GO:0045040 | outer mitochondrial membrane organization(GO:0007008) protein import into mitochondrial outer membrane(GO:0045040) |
0.1 | 1.0 | GO:0051338 | regulation of transferase activity(GO:0051338) |
0.1 | 2.2 | GO:0006413 | translational initiation(GO:0006413) |
0.1 | 0.2 | GO:0006825 | copper ion transport(GO:0006825) |
0.1 | 4.2 | GO:0006913 | nucleocytoplasmic transport(GO:0006913) nuclear transport(GO:0051169) |
0.1 | 0.1 | GO:2000243 | positive regulation of cell fate commitment(GO:0010455) positive regulation of mating type switching(GO:0031496) positive regulation of cell differentiation(GO:0045597) positive regulation of developmental process(GO:0051094) positive regulation of reproductive process(GO:2000243) |
0.1 | 0.3 | GO:0034975 | protein folding in endoplasmic reticulum(GO:0034975) |
0.1 | 0.3 | GO:0006285 | base-excision repair, AP site formation(GO:0006285) |
0.1 | 1.8 | GO:0007088 | regulation of mitotic nuclear division(GO:0007088) |
0.1 | 0.8 | GO:0031163 | iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163) |
0.1 | 1.4 | GO:0043547 | positive regulation of GTPase activity(GO:0043547) |
0.1 | 0.1 | GO:0030541 | plasmid partitioning(GO:0030541) |
0.1 | 0.2 | GO:0006276 | plasmid maintenance(GO:0006276) |
0.0 | 0.3 | GO:0042559 | folic acid-containing compound biosynthetic process(GO:0009396) pteridine-containing compound biosynthetic process(GO:0042559) |
0.0 | 0.1 | GO:0043087 | regulation of GTPase activity(GO:0043087) |
0.0 | 0.2 | GO:0006627 | protein processing involved in protein targeting to mitochondrion(GO:0006627) |
0.0 | 0.3 | GO:0006089 | lactate metabolic process(GO:0006089) |
0.0 | 0.3 | GO:0048278 | vesicle docking(GO:0048278) |
0.0 | 0.3 | GO:0000289 | nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289) |
0.0 | 0.0 | GO:0006561 | proline biosynthetic process(GO:0006561) |
0.0 | 0.1 | GO:0015856 | cytosine transport(GO:0015856) purine-containing compound transmembrane transport(GO:0072530) |
0.0 | 0.2 | GO:0031145 | anaphase-promoting complex-dependent catabolic process(GO:0031145) |
0.0 | 0.2 | GO:0043007 | maintenance of rDNA(GO:0043007) |
0.0 | 0.6 | GO:0006633 | fatty acid biosynthetic process(GO:0006633) |
0.0 | 0.3 | GO:0070682 | proteasome regulatory particle assembly(GO:0070682) |
0.0 | 0.2 | GO:0000742 | karyogamy involved in conjugation with cellular fusion(GO:0000742) |
0.0 | 0.1 | GO:0072668 | obsolete tubulin complex biogenesis(GO:0072668) |
0.0 | 0.1 | GO:0048478 | replication fork protection(GO:0048478) |
0.0 | 0.9 | GO:0006839 | mitochondrial transport(GO:0006839) |
0.0 | 0.0 | GO:0071466 | cellular response to xenobiotic stimulus(GO:0071466) |
0.0 | 0.1 | GO:0045116 | protein neddylation(GO:0045116) |
0.0 | 0.4 | GO:0006400 | tRNA modification(GO:0006400) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
4.4 | 39.9 | GO:0000144 | cellular bud neck septin ring(GO:0000144) |
4.1 | 12.3 | GO:0030428 | cell septum(GO:0030428) |
3.6 | 10.8 | GO:0017102 | methionyl glutamyl tRNA synthetase complex(GO:0017102) |
3.4 | 20.3 | GO:0032126 | eisosome(GO:0032126) |
3.3 | 16.7 | GO:0000408 | EKC/KEOPS complex(GO:0000408) |
2.8 | 14.1 | GO:0005853 | eukaryotic translation elongation factor 1 complex(GO:0005853) |
2.2 | 6.7 | GO:0070545 | PeBoW complex(GO:0070545) |
2.2 | 6.7 | GO:0032299 | ribonuclease H2 complex(GO:0032299) |
2.0 | 6.1 | GO:0045298 | polar microtubule(GO:0005827) tubulin complex(GO:0045298) |
2.0 | 8.1 | GO:0044462 | cell wall part(GO:0044426) external encapsulating structure part(GO:0044462) |
2.0 | 6.0 | GO:0005854 | nascent polypeptide-associated complex(GO:0005854) |
1.8 | 7.4 | GO:0031502 | dolichyl-phosphate-mannose-protein mannosyltransferase complex(GO:0031502) |
1.7 | 8.6 | GO:0005851 | eukaryotic translation initiation factor 2B complex(GO:0005851) |
1.7 | 6.7 | GO:0031429 | box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588) |
1.6 | 6.6 | GO:0005793 | endoplasmic reticulum-Golgi intermediate compartment(GO:0005793) |
1.6 | 12.7 | GO:0042597 | periplasmic space(GO:0042597) |
1.4 | 5.7 | GO:0005946 | alpha,alpha-trehalose-phosphate synthase complex (UDP-forming)(GO:0005946) |
1.4 | 9.9 | GO:0016459 | myosin complex(GO:0016459) |
1.3 | 4.0 | GO:0005697 | telomerase holoenzyme complex(GO:0005697) |
1.3 | 3.9 | GO:0046930 | pore complex(GO:0046930) |
1.3 | 110.4 | GO:0022625 | cytosolic large ribosomal subunit(GO:0022625) |
1.2 | 4.9 | GO:0000220 | vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220) proton-transporting V-type ATPase, V0 domain(GO:0033179) |
1.2 | 20.0 | GO:0000307 | cyclin-dependent protein kinase holoenzyme complex(GO:0000307) |
1.0 | 61.8 | GO:0022627 | cytosolic small ribosomal subunit(GO:0022627) |
1.0 | 4.8 | GO:0030478 | actin cap(GO:0030478) |
0.9 | 3.7 | GO:0033254 | vacuolar transporter chaperone complex(GO:0033254) |
0.9 | 7.3 | GO:0030127 | COPII vesicle coat(GO:0030127) |
0.9 | 2.7 | GO:0005850 | eukaryotic translation initiation factor 2 complex(GO:0005850) |
0.9 | 4.4 | GO:0034044 | exomer complex(GO:0034044) |
0.9 | 2.6 | GO:0016363 | nuclear matrix(GO:0016363) |
0.8 | 2.5 | GO:0032301 | MutSalpha complex(GO:0032301) |
0.8 | 15.7 | GO:0030137 | COPI-coated vesicle(GO:0030137) |
0.8 | 4.9 | GO:0043527 | tRNA methyltransferase complex(GO:0043527) |
0.8 | 8.0 | GO:0005666 | DNA-directed RNA polymerase III complex(GO:0005666) |
0.8 | 3.2 | GO:0031428 | box C/D snoRNP complex(GO:0031428) |
0.8 | 3.2 | GO:0030892 | mitotic cohesin complex(GO:0030892) nuclear mitotic cohesin complex(GO:0034990) |
0.8 | 13.5 | GO:0022626 | cytosolic ribosome(GO:0022626) |
0.8 | 17.4 | GO:0030134 | ER to Golgi transport vesicle(GO:0030134) |
0.8 | 13.3 | GO:0071782 | endoplasmic reticulum tubular network(GO:0071782) endoplasmic reticulum subcompartment(GO:0098827) |
0.8 | 54.9 | GO:0005576 | extracellular region(GO:0005576) |
0.7 | 4.4 | GO:0035339 | serine C-palmitoyltransferase complex(GO:0017059) SPOTS complex(GO:0035339) |
0.7 | 18.7 | GO:0005887 | integral component of plasma membrane(GO:0005887) |
0.7 | 2.7 | GO:0070860 | RNA polymerase I core factor complex(GO:0070860) |
0.7 | 4.7 | GO:0005852 | eukaryotic translation initiation factor 3 complex(GO:0005852) |
0.7 | 5.3 | GO:0005724 | nuclear heterochromatin(GO:0005720) nuclear telomeric heterochromatin(GO:0005724) telomeric heterochromatin(GO:0031933) |
0.6 | 1.9 | GO:0070762 | nuclear pore transmembrane ring(GO:0070762) |
0.6 | 5.1 | GO:0035097 | histone methyltransferase complex(GO:0035097) Set1C/COMPASS complex(GO:0048188) |
0.6 | 2.5 | GO:0000938 | GARP complex(GO:0000938) |
0.6 | 9.5 | GO:0005788 | endoplasmic reticulum lumen(GO:0005788) |
0.6 | 1.8 | GO:0042719 | mitochondrial intermembrane space protein transporter complex(GO:0042719) |
0.6 | 2.3 | GO:0044611 | nuclear pore inner ring(GO:0044611) |
0.6 | 10.8 | GO:0030118 | clathrin coat(GO:0030118) |
0.6 | 1.1 | GO:0005771 | multivesicular body(GO:0005771) |
0.5 | 4.4 | GO:0008250 | oligosaccharyltransferase complex(GO:0008250) |
0.5 | 7.6 | GO:0005736 | DNA-directed RNA polymerase I complex(GO:0005736) |
0.5 | 15.7 | GO:0005844 | polysome(GO:0005844) |
0.5 | 7.2 | GO:0000176 | nuclear exosome (RNase complex)(GO:0000176) |
0.5 | 2.0 | GO:0030907 | MBF transcription complex(GO:0030907) |
0.5 | 3.0 | GO:0048500 | signal recognition particle, endoplasmic reticulum targeting(GO:0005786) signal recognition particle(GO:0048500) |
0.5 | 3.4 | GO:0000346 | transcription export complex(GO:0000346) |
0.5 | 3.3 | GO:0034455 | t-UTP complex(GO:0034455) |
0.5 | 3.7 | GO:0005885 | Arp2/3 protein complex(GO:0005885) |
0.5 | 1.4 | GO:0070823 | HDA1 complex(GO:0070823) |
0.4 | 3.6 | GO:0005688 | U6 snRNP(GO:0005688) |
0.4 | 1.2 | GO:0034098 | VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098) |
0.4 | 3.7 | GO:0031225 | anchored component of membrane(GO:0031225) |
0.4 | 1.2 | GO:0009331 | glycerol-3-phosphate dehydrogenase complex(GO:0009331) |
0.4 | 1.6 | GO:0001401 | mitochondrial sorting and assembly machinery complex(GO:0001401) |
0.4 | 4.8 | GO:0000788 | nuclear nucleosome(GO:0000788) |
0.4 | 0.4 | GO:0000837 | Doa10p ubiquitin ligase complex(GO:0000837) |
0.4 | 2.6 | GO:0019773 | proteasome core complex, alpha-subunit complex(GO:0019773) |
0.4 | 1.4 | GO:0005971 | ribonucleoside-diphosphate reductase complex(GO:0005971) |
0.4 | 2.2 | GO:0042555 | MCM complex(GO:0042555) |
0.4 | 1.8 | GO:0016281 | eukaryotic translation initiation factor 4F complex(GO:0016281) |
0.4 | 1.4 | GO:0000120 | RNA polymerase I transcription factor complex(GO:0000120) |
0.4 | 0.7 | GO:0030869 | RENT complex(GO:0030869) |
0.3 | 1.7 | GO:0030689 | Noc complex(GO:0030689) |
0.3 | 12.7 | GO:0030176 | integral component of endoplasmic reticulum membrane(GO:0030176) |
0.3 | 0.3 | GO:0005869 | dynactin complex(GO:0005869) |
0.3 | 2.1 | GO:0016471 | vacuolar proton-transporting V-type ATPase, V1 domain(GO:0000221) vacuolar proton-transporting V-type ATPase complex(GO:0016471) proton-transporting V-type ATPase complex(GO:0033176) proton-transporting V-type ATPase, V1 domain(GO:0033180) |
0.3 | 0.9 | GO:0000159 | protein phosphatase type 2A complex(GO:0000159) |
0.3 | 20.3 | GO:0005815 | microtubule organizing center(GO:0005815) spindle pole body(GO:0005816) |
0.3 | 10.4 | GO:0005811 | lipid particle(GO:0005811) |
0.3 | 2.8 | GO:0000243 | commitment complex(GO:0000243) |
0.3 | 1.1 | GO:0005834 | heterotrimeric G-protein complex(GO:0005834) |
0.3 | 60.2 | GO:0005829 | cytosol(GO:0005829) |
0.3 | 1.3 | GO:0031414 | N-terminal protein acetyltransferase complex(GO:0031414) |
0.3 | 1.3 | GO:0000506 | glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506) |
0.2 | 0.7 | GO:0043529 | GET complex(GO:0043529) |
0.2 | 41.7 | GO:0005730 | nucleolus(GO:0005730) |
0.2 | 0.7 | GO:0030119 | AP-type membrane coat adaptor complex(GO:0030119) |
0.2 | 2.0 | GO:0031228 | integral component of Golgi membrane(GO:0030173) intrinsic component of Golgi membrane(GO:0031228) |
0.2 | 1.1 | GO:0031391 | DNA replication factor C complex(GO:0005663) Rad17 RFC-like complex(GO:0031389) Elg1 RFC-like complex(GO:0031391) |
0.2 | 42.9 | GO:0005759 | mitochondrial matrix(GO:0005759) |
0.2 | 3.2 | GO:0000784 | nuclear chromosome, telomeric region(GO:0000784) |
0.2 | 1.2 | GO:0032432 | actin filament bundle(GO:0032432) |
0.2 | 50.6 | GO:0005783 | endoplasmic reticulum(GO:0005783) |
0.2 | 1.3 | GO:0008540 | proteasome regulatory particle, base subcomplex(GO:0008540) |
0.2 | 6.7 | GO:0031965 | nuclear membrane(GO:0031965) |
0.2 | 0.7 | GO:0030906 | retromer, cargo-selective complex(GO:0030906) |
0.2 | 1.7 | GO:0000781 | chromosome, telomeric region(GO:0000781) |
0.2 | 5.3 | GO:0005635 | nuclear envelope(GO:0005635) |
0.2 | 0.7 | GO:0016602 | CCAAT-binding factor complex(GO:0016602) |
0.2 | 1.9 | GO:0010494 | cytoplasmic stress granule(GO:0010494) |
0.2 | 1.9 | GO:0030014 | CCR4-NOT complex(GO:0030014) |
0.1 | 1.0 | GO:0005658 | alpha DNA polymerase:primase complex(GO:0005658) |
0.1 | 16.8 | GO:0005933 | cellular bud(GO:0005933) |
0.1 | 0.5 | GO:0017053 | transcriptional repressor complex(GO:0017053) |
0.1 | 1.3 | GO:0005685 | U1 snRNP(GO:0005685) |
0.1 | 2.1 | GO:0031305 | integral component of mitochondrial inner membrane(GO:0031305) |
0.1 | 0.2 | GO:0005796 | Golgi lumen(GO:0005796) |
0.1 | 4.4 | GO:0000139 | Golgi membrane(GO:0000139) |
0.1 | 0.4 | GO:0031901 | early endosome membrane(GO:0031901) |
0.1 | 0.6 | GO:0098799 | outer mitochondrial membrane protein complex(GO:0098799) |
0.1 | 0.4 | GO:0055087 | Ski complex(GO:0055087) |
0.1 | 1.1 | GO:0019005 | SCF ubiquitin ligase complex(GO:0019005) |
0.1 | 1.9 | GO:0043332 | mating projection tip(GO:0043332) |
0.1 | 0.9 | GO:0016514 | SWI/SNF complex(GO:0016514) BAF-type complex(GO:0090544) |
0.1 | 0.2 | GO:0042720 | mitochondrial inner membrane peptidase complex(GO:0042720) |
0.1 | 0.3 | GO:0031201 | SNARE complex(GO:0031201) |
0.0 | 0.1 | GO:0030008 | TRAPP complex(GO:0030008) |
0.0 | 0.3 | GO:0005671 | Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671) |
0.0 | 0.3 | GO:0005665 | DNA-directed RNA polymerase II, core complex(GO:0005665) |
0.0 | 8.5 | GO:0005886 | plasma membrane(GO:0005886) |
0.0 | 0.1 | GO:0071819 | DUBm complex(GO:0071819) |
0.0 | 0.2 | GO:0005775 | vacuolar lumen(GO:0005775) |
0.0 | 0.1 | GO:0042721 | mitochondrial inner membrane protein insertion complex(GO:0042721) |
0.0 | 0.2 | GO:0031261 | DNA replication preinitiation complex(GO:0031261) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
7.0 | 42.1 | GO:0016846 | carbon-sulfur lyase activity(GO:0016846) |
5.1 | 20.5 | GO:0016634 | oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor(GO:0016634) |
5.1 | 15.2 | GO:0003938 | IMP dehydrogenase activity(GO:0003938) |
4.1 | 12.2 | GO:0015166 | polyol transmembrane transporter activity(GO:0015166) |
3.9 | 15.7 | GO:0019206 | nucleoside kinase activity(GO:0019206) |
3.6 | 10.7 | GO:0004488 | methylenetetrahydrofolate dehydrogenase (NADP+) activity(GO:0004488) |
3.2 | 19.3 | GO:0042123 | glucanosyltransferase activity(GO:0042123) 1,3-beta-glucanosyltransferase activity(GO:0042124) |
3.2 | 31.8 | GO:0005216 | ion channel activity(GO:0005216) |
3.1 | 9.4 | GO:0070568 | guanylyltransferase activity(GO:0070568) |
3.1 | 9.3 | GO:0009922 | fatty acid elongase activity(GO:0009922) |
3.0 | 12.2 | GO:0017057 | 6-phosphogluconolactonase activity(GO:0017057) |
3.0 | 9.1 | GO:0004338 | glucan exo-1,3-beta-glucosidase activity(GO:0004338) |
3.0 | 11.8 | GO:0000297 | spermine transmembrane transporter activity(GO:0000297) |
2.8 | 17.1 | GO:0005545 | 1-phosphatidylinositol binding(GO:0005545) |
2.7 | 16.0 | GO:0047429 | nucleoside-triphosphate diphosphatase activity(GO:0047429) |
2.5 | 9.9 | GO:0016661 | oxidoreductase activity, acting on other nitrogenous compounds as donors(GO:0016661) |
2.5 | 14.8 | GO:0004022 | alcohol dehydrogenase (NAD) activity(GO:0004022) |
2.4 | 9.6 | GO:0008172 | S-methyltransferase activity(GO:0008172) |
2.4 | 23.9 | GO:0032934 | steroid binding(GO:0005496) sterol binding(GO:0032934) |
2.4 | 11.9 | GO:0004707 | MAP kinase activity(GO:0004707) |
2.3 | 11.3 | GO:0017169 | CDP-alcohol phosphatidyltransferase activity(GO:0017169) |
2.3 | 11.3 | GO:0070546 | L-phenylalanine aminotransferase activity(GO:0070546) L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130) |
2.2 | 6.5 | GO:0004100 | chitin synthase activity(GO:0004100) |
2.2 | 6.5 | GO:0051219 | phosphoprotein binding(GO:0051219) |
2.0 | 53.1 | GO:0016538 | cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538) |
2.0 | 68.5 | GO:0016875 | aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876) |
1.9 | 7.7 | GO:0016841 | ammonia-lyase activity(GO:0016841) |
1.9 | 9.6 | GO:0004026 | alcohol O-acetyltransferase activity(GO:0004026) alcohol O-acyltransferase activity(GO:0034318) |
1.9 | 7.7 | GO:0004467 | long-chain fatty acid-CoA ligase activity(GO:0004467) |
1.9 | 7.7 | GO:0004614 | phosphoglucomutase activity(GO:0004614) |
1.8 | 5.5 | GO:0008559 | xenobiotic-transporting ATPase activity(GO:0008559) xenobiotic transporter activity(GO:0042910) |
1.8 | 5.5 | GO:0019203 | carbohydrate phosphatase activity(GO:0019203) sugar-phosphatase activity(GO:0050308) |
1.7 | 1.7 | GO:0004805 | trehalose-phosphatase activity(GO:0004805) |
1.7 | 6.7 | GO:0004523 | RNA-DNA hybrid ribonuclease activity(GO:0004523) |
1.7 | 6.7 | GO:0015146 | pentose transmembrane transporter activity(GO:0015146) |
1.6 | 4.9 | GO:0004809 | tRNA (guanine-N2-)-methyltransferase activity(GO:0004809) |
1.6 | 8.1 | GO:0000146 | microfilament motor activity(GO:0000146) |
1.6 | 4.7 | GO:0019003 | GDP binding(GO:0019003) |
1.5 | 4.6 | GO:0004575 | beta-fructofuranosidase activity(GO:0004564) sucrose alpha-glucosidase activity(GO:0004575) |
1.5 | 7.5 | GO:0003993 | acid phosphatase activity(GO:0003993) |
1.4 | 4.3 | GO:0015114 | phosphate ion transmembrane transporter activity(GO:0015114) |
1.4 | 7.1 | GO:0017048 | Rho GTPase binding(GO:0017048) |
1.4 | 7.1 | GO:0003705 | transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705) |
1.4 | 14.1 | GO:0031490 | chromatin DNA binding(GO:0031490) |
1.4 | 4.1 | GO:0019202 | amino acid kinase activity(GO:0019202) |
1.4 | 8.1 | GO:0030145 | manganese ion binding(GO:0030145) |
1.4 | 20.3 | GO:0015926 | glucosidase activity(GO:0015926) |
1.3 | 8.0 | GO:0005375 | copper ion transmembrane transporter activity(GO:0005375) |
1.3 | 4.0 | GO:0043891 | glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891) |
1.3 | 4.0 | GO:0003825 | alpha,alpha-trehalose-phosphate synthase (UDP-forming) activity(GO:0003825) |
1.3 | 6.6 | GO:0008443 | phosphofructokinase activity(GO:0008443) |
1.3 | 3.8 | GO:0008097 | 5S rRNA binding(GO:0008097) |
1.2 | 1.2 | GO:0015248 | sterol transporter activity(GO:0015248) |
1.2 | 6.2 | GO:0000033 | alpha-1,3-mannosyltransferase activity(GO:0000033) |
1.2 | 7.4 | GO:0004169 | dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169) |
1.2 | 15.8 | GO:0003746 | translation elongation factor activity(GO:0003746) |
1.1 | 6.5 | GO:0016709 | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709) |
1.1 | 10.6 | GO:0009982 | pseudouridine synthase activity(GO:0009982) |
1.0 | 2.1 | GO:0031683 | G-protein beta/gamma-subunit complex binding(GO:0031683) |
1.0 | 3.1 | GO:0033592 | RNA strand annealing activity(GO:0033592) annealing activity(GO:0097617) |
1.0 | 10.3 | GO:0019239 | deaminase activity(GO:0019239) |
1.0 | 12.0 | GO:0005199 | structural constituent of cell wall(GO:0005199) |
1.0 | 5.9 | GO:0015198 | oligopeptide transporter activity(GO:0015198) |
1.0 | 5.9 | GO:0016744 | transferase activity, transferring aldehyde or ketonic groups(GO:0016744) |
1.0 | 3.9 | GO:0005528 | macrolide binding(GO:0005527) FK506 binding(GO:0005528) |
1.0 | 4.9 | GO:0005092 | GDP-dissociation inhibitor activity(GO:0005092) |
1.0 | 19.4 | GO:0016831 | carboxy-lyase activity(GO:0016831) |
0.9 | 10.3 | GO:0015238 | drug transmembrane transporter activity(GO:0015238) |
0.9 | 11.3 | GO:0015035 | protein disulfide oxidoreductase activity(GO:0015035) disulfide oxidoreductase activity(GO:0015036) |
0.9 | 2.7 | GO:0001169 | transcription factor activity, RNA polymerase I CORE element sequence-specific binding(GO:0001169) transcription factor activity, RNA polymerase I CORE element binding transcription factor recruiting(GO:0001187) |
0.9 | 6.1 | GO:0016861 | intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861) |
0.8 | 2.5 | GO:0015665 | alcohol transmembrane transporter activity(GO:0015665) |
0.8 | 169.7 | GO:0003735 | structural constituent of ribosome(GO:0003735) |
0.8 | 4.1 | GO:0070273 | phosphatidylinositol-4-phosphate binding(GO:0070273) |
0.8 | 3.2 | GO:0000774 | adenyl-nucleotide exchange factor activity(GO:0000774) |
0.8 | 8.0 | GO:0001056 | RNA polymerase III activity(GO:0001056) |
0.8 | 3.2 | GO:0016863 | intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863) |
0.8 | 6.8 | GO:0010181 | FMN binding(GO:0010181) |
0.8 | 3.0 | GO:0008242 | omega peptidase activity(GO:0008242) |
0.8 | 5.3 | GO:0016866 | intramolecular transferase activity(GO:0016866) |
0.7 | 27.5 | GO:0016765 | transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765) |
0.7 | 2.9 | GO:0004622 | lysophospholipase activity(GO:0004622) |
0.7 | 2.2 | GO:0004930 | G-protein coupled receptor activity(GO:0004930) |
0.7 | 1.4 | GO:0015216 | purine nucleotide transmembrane transporter activity(GO:0015216) |
0.7 | 10.0 | GO:0070566 | adenylyltransferase activity(GO:0070566) |
0.7 | 10.6 | GO:0050661 | NADP binding(GO:0050661) |
0.7 | 4.9 | GO:0015211 | purine nucleoside transmembrane transporter activity(GO:0015211) |
0.7 | 42.4 | GO:0003924 | GTPase activity(GO:0003924) |
0.7 | 10.8 | GO:0042803 | protein homodimerization activity(GO:0042803) |
0.6 | 6.5 | GO:0005516 | calmodulin binding(GO:0005516) |
0.6 | 5.1 | GO:0042800 | histone methyltransferase activity (H3-K4 specific)(GO:0042800) |
0.6 | 5.0 | GO:0005385 | zinc ion transmembrane transporter activity(GO:0005385) |
0.6 | 1.8 | GO:0016717 | oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water(GO:0016717) |
0.6 | 1.8 | GO:0034596 | phosphatidylinositol phosphate 4-phosphatase activity(GO:0034596) phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812) |
0.6 | 16.5 | GO:0016853 | isomerase activity(GO:0016853) |
0.6 | 1.8 | GO:0016300 | tRNA (uracil) methyltransferase activity(GO:0016300) |
0.6 | 6.0 | GO:0004252 | serine-type endopeptidase activity(GO:0004252) |
0.6 | 3.6 | GO:0004033 | aldo-keto reductase (NADP) activity(GO:0004033) alcohol dehydrogenase (NADP+) activity(GO:0008106) |
0.6 | 3.4 | GO:0016668 | oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor(GO:0016668) |
0.5 | 3.8 | GO:0016799 | hydrolase activity, hydrolyzing N-glycosyl compounds(GO:0016799) |
0.5 | 4.4 | GO:0004579 | oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579) |
0.5 | 7.6 | GO:0001054 | RNA polymerase I activity(GO:0001054) |
0.5 | 2.1 | GO:0008312 | 7S RNA binding(GO:0008312) |
0.5 | 1.5 | GO:0031370 | eukaryotic initiation factor 4G binding(GO:0031370) |
0.5 | 2.4 | GO:0005338 | nucleotide-sugar transmembrane transporter activity(GO:0005338) |
0.5 | 1.0 | GO:0016774 | phosphotransferase activity, carboxyl group as acceptor(GO:0016774) |
0.5 | 2.9 | GO:0019201 | nucleotide kinase activity(GO:0019201) |
0.5 | 1.9 | GO:0003725 | double-stranded RNA binding(GO:0003725) |
0.5 | 5.7 | GO:0016884 | carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884) |
0.5 | 1.4 | GO:0004551 | nucleotide diphosphatase activity(GO:0004551) |
0.5 | 12.3 | GO:0004722 | protein serine/threonine phosphatase activity(GO:0004722) |
0.4 | 0.9 | GO:0042134 | rRNA primary transcript binding(GO:0042134) |
0.4 | 1.3 | GO:0019205 | nucleobase-containing compound kinase activity(GO:0019205) |
0.4 | 0.9 | GO:0016838 | carbon-oxygen lyase activity, acting on phosphates(GO:0016838) |
0.4 | 1.3 | GO:0003747 | translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079) |
0.4 | 1.7 | GO:0016721 | superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721) |
0.4 | 6.2 | GO:0008170 | N-methyltransferase activity(GO:0008170) |
0.4 | 4.4 | GO:0051015 | actin filament binding(GO:0051015) |
0.4 | 1.6 | GO:0051377 | mannose-ethanolamine phosphotransferase activity(GO:0051377) |
0.4 | 0.8 | GO:0001046 | core promoter sequence-specific DNA binding(GO:0001046) |
0.4 | 1.2 | GO:0003841 | 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841) |
0.4 | 0.8 | GO:0001163 | RNA polymerase I regulatory region DNA binding(GO:0001013) RNA polymerase I regulatory region sequence-specific DNA binding(GO:0001163) |
0.4 | 1.1 | GO:0005519 | cytoskeletal regulatory protein binding(GO:0005519) |
0.4 | 1.4 | GO:0061731 | ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups(GO:0016725) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731) |
0.4 | 5.8 | GO:0042162 | telomeric DNA binding(GO:0042162) |
0.4 | 3.2 | GO:0004596 | peptide alpha-N-acetyltransferase activity(GO:0004596) |
0.4 | 1.8 | GO:0017022 | myosin binding(GO:0017022) |
0.3 | 18.7 | GO:0008092 | cytoskeletal protein binding(GO:0008092) |
0.3 | 9.7 | GO:0008135 | translation initiation factor activity(GO:0003743) translation factor activity, RNA binding(GO:0008135) |
0.3 | 3.1 | GO:0004177 | aminopeptidase activity(GO:0004177) |
0.3 | 1.7 | GO:0004749 | ribose phosphate diphosphokinase activity(GO:0004749) |
0.3 | 0.7 | GO:0001167 | RNA polymerase I transcription factor activity, sequence-specific DNA binding(GO:0001167) |
0.3 | 2.0 | GO:0015215 | nucleotide transmembrane transporter activity(GO:0015215) |
0.3 | 1.3 | GO:0005487 | nucleocytoplasmic transporter activity(GO:0005487) |
0.3 | 2.2 | GO:0016742 | hydroxymethyl-, formyl- and related transferase activity(GO:0016742) |
0.3 | 3.1 | GO:0001133 | RNA polymerase II transcription factor activity, sequence-specific transcription regulatory region DNA binding(GO:0001133) |
0.3 | 3.9 | GO:0005048 | signal sequence binding(GO:0005048) peptide binding(GO:0042277) |
0.3 | 0.8 | GO:0015116 | secondary active sulfate transmembrane transporter activity(GO:0008271) sulfate transmembrane transporter activity(GO:0015116) |
0.3 | 0.8 | GO:0001181 | transcription factor activity, core RNA polymerase I binding(GO:0001181) |
0.3 | 0.3 | GO:0015605 | organophosphate ester transmembrane transporter activity(GO:0015605) |
0.3 | 1.4 | GO:0016423 | tRNA (guanine) methyltransferase activity(GO:0016423) |
0.3 | 12.4 | GO:0016791 | phosphatase activity(GO:0016791) |
0.3 | 1.8 | GO:0008175 | tRNA methyltransferase activity(GO:0008175) |
0.3 | 2.3 | GO:0030276 | clathrin binding(GO:0030276) |
0.3 | 1.3 | GO:0017176 | phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176) |
0.2 | 1.2 | GO:0016655 | oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor(GO:0016655) |
0.2 | 1.9 | GO:0080025 | phosphatidylinositol-3,5-bisphosphate binding(GO:0080025) |
0.2 | 2.9 | GO:0016409 | palmitoyltransferase activity(GO:0016409) |
0.2 | 1.9 | GO:0043022 | ribosome binding(GO:0043022) |
0.2 | 3.2 | GO:0004298 | threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003) |
0.2 | 0.7 | GO:0004629 | phospholipase C activity(GO:0004629) |
0.2 | 1.7 | GO:0070001 | aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001) |
0.2 | 1.1 | GO:0003923 | GPI-anchor transamidase activity(GO:0003923) |
0.2 | 0.6 | GO:0004634 | phosphopyruvate hydratase activity(GO:0004634) |
0.2 | 1.0 | GO:0001132 | RNA polymerase II transcription factor activity, TBP-class protein binding, involved in preinitiation complex assembly(GO:0001129) RNA polymerase II transcription factor activity, TBP-class protein binding(GO:0001132) |
0.2 | 11.7 | GO:0008565 | protein transporter activity(GO:0008565) |
0.2 | 4.8 | GO:0017056 | structural constituent of nuclear pore(GO:0017056) |
0.2 | 0.9 | GO:0008409 | 5'-3' exonuclease activity(GO:0008409) |
0.2 | 1.1 | GO:0003689 | DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170) |
0.2 | 3.1 | GO:0030515 | snoRNA binding(GO:0030515) |
0.2 | 0.5 | GO:0017070 | U6 snRNA binding(GO:0017070) |
0.2 | 0.7 | GO:0009378 | four-way junction helicase activity(GO:0009378) |
0.2 | 5.4 | GO:0000030 | mannosyltransferase activity(GO:0000030) |
0.2 | 6.2 | GO:0016410 | N-acyltransferase activity(GO:0016410) |
0.2 | 5.7 | GO:0003724 | RNA helicase activity(GO:0003724) |
0.2 | 0.5 | GO:0016882 | cyclo-ligase activity(GO:0016882) |
0.1 | 2.5 | GO:0032561 | GTP binding(GO:0005525) guanyl nucleotide binding(GO:0019001) guanyl ribonucleotide binding(GO:0032561) |
0.1 | 1.1 | GO:0019200 | carbohydrate kinase activity(GO:0019200) |
0.1 | 1.1 | GO:0097472 | cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin-dependent protein kinase activity(GO:0097472) |
0.1 | 1.7 | GO:0001671 | ATPase activator activity(GO:0001671) |
0.1 | 0.5 | GO:0005384 | manganese ion transmembrane transporter activity(GO:0005384) |
0.1 | 6.5 | GO:0051082 | unfolded protein binding(GO:0051082) |
0.1 | 0.6 | GO:0004535 | poly(A)-specific ribonuclease activity(GO:0004535) |
0.1 | 1.3 | GO:0051087 | chaperone binding(GO:0051087) |
0.1 | 2.8 | GO:0030674 | protein binding, bridging(GO:0030674) |
0.1 | 0.3 | GO:0004497 | monooxygenase activity(GO:0004497) |
0.1 | 0.3 | GO:0015103 | inorganic anion transmembrane transporter activity(GO:0015103) |
0.1 | 2.6 | GO:0043130 | ubiquitin binding(GO:0043130) |
0.1 | 0.3 | GO:0008536 | Ran GTPase binding(GO:0008536) |
0.1 | 0.7 | GO:0043495 | protein anchor(GO:0043495) |
0.1 | 0.7 | GO:0005381 | iron ion transmembrane transporter activity(GO:0005381) |
0.1 | 2.1 | GO:0016811 | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides(GO:0016811) |
0.1 | 0.3 | GO:0008157 | protein phosphatase 1 binding(GO:0008157) |
0.1 | 2.5 | GO:0005085 | guanyl-nucleotide exchange factor activity(GO:0005085) |
0.1 | 0.1 | GO:0008144 | drug binding(GO:0008144) |
0.1 | 0.3 | GO:0001055 | RNA polymerase II activity(GO:0001055) |
0.1 | 0.2 | GO:0036002 | pre-mRNA binding(GO:0036002) |
0.1 | 1.1 | GO:0004520 | endodeoxyribonuclease activity(GO:0004520) |
0.0 | 0.3 | GO:0034062 | DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062) |
0.0 | 0.4 | GO:0004175 | endopeptidase activity(GO:0004175) |
0.0 | 1.5 | GO:0005096 | GTPase activator activity(GO:0005096) |
0.0 | 0.9 | GO:0008237 | metallopeptidase activity(GO:0008237) |
0.0 | 0.3 | GO:0019904 | protein domain specific binding(GO:0019904) |
0.0 | 0.4 | GO:0000384 | first spliceosomal transesterification activity(GO:0000384) |
0.0 | 0.1 | GO:0030060 | L-malate dehydrogenase activity(GO:0030060) |
0.0 | 0.2 | GO:0008526 | phosphatidylcholine transporter activity(GO:0008525) phosphatidylinositol transporter activity(GO:0008526) |
0.0 | 0.4 | GO:0005319 | lipid transporter activity(GO:0005319) |
0.0 | 0.1 | GO:0004708 | MAP kinase kinase activity(GO:0004708) |
0.0 | 0.2 | GO:0035064 | methylated histone binding(GO:0035064) |
0.0 | 0.1 | GO:0004128 | cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128) |
0.0 | 0.5 | GO:0003688 | DNA replication origin binding(GO:0003688) |
0.0 | 0.1 | GO:0008641 | small protein activating enzyme activity(GO:0008641) |
0.0 | 0.5 | GO:0016757 | transferase activity, transferring glycosyl groups(GO:0016757) |
0.0 | 0.0 | GO:0016886 | ligase activity, forming phosphoric ester bonds(GO:0016886) |
0.0 | 0.1 | GO:0003727 | single-stranded RNA binding(GO:0003727) |
0.0 | 0.1 | GO:0004679 | AMP-activated protein kinase activity(GO:0004679) |
0.0 | 0.1 | GO:0072509 | divalent inorganic cation transmembrane transporter activity(GO:0072509) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
4.1 | 12.3 | PID HIF1 TFPATHWAY | HIF-1-alpha transcription factor network |
2.8 | 8.4 | PID CDC42 PATHWAY | CDC42 signaling events |
1.5 | 3.1 | PID P38 ALPHA BETA DOWNSTREAM PATHWAY | Signaling mediated by p38-alpha and p38-beta |
1.0 | 2.0 | PID A6B1 A6B4 INTEGRIN PATHWAY | a6b1 and a6b4 Integrin signaling |
0.5 | 1.5 | PID AR PATHWAY | Coregulation of Androgen receptor activity |
0.5 | 2.3 | PID PLK1 PATHWAY | PLK1 signaling events |
0.5 | 1.8 | PID UPA UPAR PATHWAY | Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling |
0.3 | 0.3 | PID ANGIOPOIETIN RECEPTOR PATHWAY | Angiopoietin receptor Tie2-mediated signaling |
0.3 | 0.3 | PID INTEGRIN A4B1 PATHWAY | Alpha4 beta1 integrin signaling events |
0.2 | 0.7 | SA G1 AND S PHASES | Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition. |
0.2 | 0.8 | NABA ECM GLYCOPROTEINS | Genes encoding structural ECM glycoproteins |
0.2 | 0.6 | PID E2F PATHWAY | E2F transcription factor network |
0.2 | 0.6 | PID AVB3 INTEGRIN PATHWAY | Integrins in angiogenesis |
0.2 | 1.7 | PID ATR PATHWAY | ATR signaling pathway |
0.1 | 0.3 | PID MYC PATHWAY | C-MYC pathway |
0.1 | 0.1 | PID CASPASE PATHWAY | Caspase cascade in apoptosis |
0.1 | 0.2 | PID TRKR PATHWAY | Neurotrophic factor-mediated Trk receptor signaling |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
2.5 | 7.4 | REACTOME SIGNALING BY RHO GTPASES | Genes involved in Signaling by Rho GTPases |
2.1 | 8.5 | REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS | Genes involved in Glycerophospholipid biosynthesis |
2.1 | 6.2 | REACTOME ETHANOL OXIDATION | Genes involved in Ethanol oxidation |
1.4 | 5.7 | REACTOME GLYCOLYSIS | Genes involved in Glycolysis |
1.3 | 4.0 | REACTOME ACTIVATED TLR4 SIGNALLING | Genes involved in Activated TLR4 signalling |
1.2 | 8.6 | REACTOME ACTIVATION OF THE MRNA UPON BINDING OF THE CAP BINDING COMPLEX AND EIFS AND SUBSEQUENT BINDING TO 43S | Genes involved in Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S |
1.2 | 3.6 | REACTOME CITRIC ACID CYCLE TCA CYCLE | Genes involved in Citric acid cycle (TCA cycle) |
0.9 | 7.2 | REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE | Genes involved in mRNA Decay by 5' to 3' Exoribonuclease |
0.9 | 2.6 | REACTOME MHC CLASS II ANTIGEN PRESENTATION | Genes involved in MHC class II antigen presentation |
0.7 | 3.6 | REACTOME GLUCOSE METABOLISM | Genes involved in Glucose metabolism |
0.7 | 2.0 | REACTOME SULFUR AMINO ACID METABOLISM | Genes involved in Sulfur amino acid metabolism |
0.6 | 1.9 | REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS | Genes involved in Synthesis of substrates in N-glycan biosythesis |
0.6 | 9.2 | REACTOME 3 UTR MEDIATED TRANSLATIONAL REGULATION | Genes involved in 3' -UTR-mediated translational regulation |
0.5 | 2.0 | REACTOME APOPTOSIS | Genes involved in Apoptosis |
0.5 | 1.8 | REACTOME CLASS A1 RHODOPSIN LIKE RECEPTORS | Genes involved in Class A/1 (Rhodopsin-like receptors) |
0.4 | 3.0 | REACTOME PROTEIN FOLDING | Genes involved in Protein folding |
0.4 | 1.7 | REACTOME PLATELET ACTIVATION SIGNALING AND AGGREGATION | Genes involved in Platelet activation, signaling and aggregation |
0.4 | 2.6 | REACTOME UNWINDING OF DNA | Genes involved in Unwinding of DNA |
0.3 | 3.2 | REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN | Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein |
0.3 | 1.1 | REACTOME NUCLEOTIDE EXCISION REPAIR | Genes involved in Nucleotide Excision Repair |
0.2 | 1.4 | REACTOME CYTOKINE SIGNALING IN IMMUNE SYSTEM | Genes involved in Cytokine Signaling in Immune system |
0.2 | 1.2 | REACTOME TRANSLATION | Genes involved in Translation |
0.1 | 0.7 | REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT | Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT) |
0.1 | 0.3 | REACTOME G1 S SPECIFIC TRANSCRIPTION | Genes involved in G1/S-Specific Transcription |
0.1 | 0.2 | REACTOME NGF SIGNALLING VIA TRKA FROM THE PLASMA MEMBRANE | Genes involved in NGF signalling via TRKA from the plasma membrane |
0.1 | 0.8 | REACTOME MITOTIC PROMETAPHASE | Genes involved in Mitotic Prometaphase |
0.0 | 0.1 | REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE | Genes involved in Synthesis of PIPs at the Golgi membrane |