Results for USV1
Z-value: 0.73
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Transcription factors associated with USV1
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
|
USV1
|
S000006151 | Putative transcription factor containing a C2H2 zinc finger |
Activity-expression correlation:
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| YPR160W Show fit | 3.34 |
Non-essential glycogen phosphorylase required for the mobilization of glycogen, activity is regulated by cyclic AMP-mediated phosphorylation, expression is regulated by stress-response elements and by the HOG MAP kinase pathway |
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| YIL162W Show fit | 2.73 |
Invertase, sucrose hydrolyzing enzyme; a secreted, glycosylated form is regulated by glucose repression, and an intracellular, nonglycosylated enzyme is produced constitutively |
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| YFR053C Show fit | 2.72 |
Hexokinase isoenzyme 1, a cytosolic protein that catalyzes phosphorylation of glucose during glucose metabolism; expression is highest during growth on non-glucose carbon sources; glucose-induced repression involves the hexokinase Hxk2p |
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| YHL021C Show fit | 2.41 |
Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; null mutant displays decreased frequency of mitochondrial genome loss (petite formation) |
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| YFR015C Show fit | 2.25 |
Glycogen synthase with similarity to Gsy2p, the more highly expressed yeast homolog; expression induced by glucose limitation, nitrogen starvation, environmental stress, and entry into stationary phase |
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| YER067W Show fit | 1.87 |
Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus; YER067W is not an essential gene |
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| YEL039C Show fit | 1.69 |
Cytochrome c isoform 2, expressed under hypoxic conditions; electron carrier of the mitochondrial intermembrane space that transfers electrons from ubiquinone-cytochrome c oxidoreductase to cytochrome c oxidase during cellular respiration |
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| YDR516C Show fit | 1.64 |
Non-essential protein of unknown function required for transcriptional induction of the early meiotic-specific transcription factor IME1; required for sporulation; expression is regulated by glucose-repression transcription factors Mig1/2p |
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| YOL154W Show fit | 1.63 |
Putative GPI-anchored protein; transcription is induced under low-zinc conditions, as mediated by the Zap1p transcription factor, and at alkaline pH |
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| YBR072W Show fit | 1.57 |
Small heat shock protein (sHSP) with chaperone activity; forms hollow, sphere-shaped oligomers that suppress unfolded proteins aggregation; oligomer activation requires a heat-induced conformational change; not expressed in unstressed cells |
Network of associatons between targets according to the STRING database.
First level regulatory network of USV1
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 5.2 | GO:0005978 | glycogen biosynthetic process(GO:0005978) |
| 0.9 | 4.5 | GO:0005980 | glycogen catabolic process(GO:0005980) |
| 0.9 | 2.7 | GO:0015755 | fructose transport(GO:0015755) |
| 0.3 | 2.7 | GO:0005987 | sucrose metabolic process(GO:0005985) sucrose catabolic process(GO:0005987) |
| 0.2 | 2.7 | GO:0051156 | glucose 6-phosphate metabolic process(GO:0051156) |
| 0.3 | 2.3 | GO:0006123 | mitochondrial electron transport, cytochrome c to oxygen(GO:0006123) |
| 0.7 | 2.0 | GO:0032780 | negative regulation of ATPase activity(GO:0032780) |
| 0.0 | 2.0 | GO:0009060 | aerobic respiration(GO:0009060) |
| 0.5 | 1.4 | GO:0042744 | hydrogen peroxide catabolic process(GO:0042744) |
| 0.3 | 1.3 | GO:0000023 | maltose metabolic process(GO:0000023) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 12.9 | GO:0005739 | mitochondrion(GO:0005739) |
| 0.1 | 4.6 | GO:0005576 | extracellular region(GO:0005576) |
| 0.1 | 4.0 | GO:0070469 | respiratory chain(GO:0070469) |
| 0.0 | 2.4 | GO:0005758 | mitochondrial intermembrane space(GO:0005758) |
| 0.1 | 1.8 | GO:0009277 | fungal-type cell wall(GO:0009277) |
| 0.5 | 1.5 | GO:0000015 | phosphopyruvate hydratase complex(GO:0000015) |
| 0.1 | 1.3 | GO:0005887 | integral component of plasma membrane(GO:0005887) |
| 0.0 | 1.3 | GO:0005811 | lipid particle(GO:0005811) |
| 0.2 | 1.0 | GO:0031235 | intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235) |
| 0.1 | 1.0 | GO:0042597 | periplasmic space(GO:0042597) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.4 | 4.8 | GO:0035251 | UDP-glucosyltransferase activity(GO:0035251) |
| 1.1 | 4.4 | GO:0004396 | hexokinase activity(GO:0004396) |
| 0.0 | 3.7 | GO:0051082 | unfolded protein binding(GO:0051082) |
| 0.2 | 3.2 | GO:0046906 | heme binding(GO:0020037) tetrapyrrole binding(GO:0046906) |
| 0.0 | 3.1 | GO:0016758 | transferase activity, transferring hexosyl groups(GO:0016758) |
| 0.9 | 2.7 | GO:0004575 | beta-fructofuranosidase activity(GO:0004564) sucrose alpha-glucosidase activity(GO:0004575) |
| 0.3 | 2.6 | GO:0016701 | oxidoreductase activity, acting on single donors with incorporation of molecular oxygen(GO:0016701) oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702) |
| 0.1 | 2.2 | GO:0004553 | hydrolase activity, hydrolyzing O-glycosyl compounds(GO:0004553) |
| 0.3 | 1.9 | GO:0072349 | modified amino acid transmembrane transporter activity(GO:0072349) |
| 0.2 | 1.7 | GO:0005216 | ion channel activity(GO:0005216) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.4 | 1.3 | PID HIF1 TFPATHWAY | HIF-1-alpha transcription factor network |
| 0.2 | 0.6 | PID AR PATHWAY | Coregulation of Androgen receptor activity |
| 0.0 | 0.1 | PID P38 ALPHA BETA DOWNSTREAM PATHWAY | Signaling mediated by p38-alpha and p38-beta |
| 0.0 | 0.0 | PID CDC42 PATHWAY | CDC42 signaling events |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 1.4 | REACTOME GLUCOSE METABOLISM | Genes involved in Glucose metabolism |
| 0.3 | 1.2 | REACTOME GLYCOLYSIS | Genes involved in Glycolysis |
| 0.0 | 0.4 | REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES | Genes involved in Metabolism of amino acids and derivatives |
| 0.1 | 0.2 | REACTOME MEIOTIC SYNAPSIS | Genes involved in Meiotic Synapsis |
| 0.1 | 0.2 | REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS | Genes involved in Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. |
| 0.1 | 0.2 | REACTOME MYD88 MAL CASCADE INITIATED ON PLASMA MEMBRANE | Genes involved in MyD88:Mal cascade initiated on plasma membrane |
| 0.0 | 0.0 | REACTOME SIGNALING BY ROBO RECEPTOR | Genes involved in Signaling by Robo receptor |
| 0.0 | 0.0 | REACTOME ETHANOL OXIDATION | Genes involved in Ethanol oxidation |