Results for TYE7
Z-value: 0.39
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Transcription factors associated with TYE7
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
|
TYE7
|
S000005871 | Serine-rich protein that contains a bHLH DNA binding motif |
Activity-expression correlation:
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| YCR021C Show fit | 2.28 |
Hydrophobic plasma membrane localized, stress-responsive protein that negatively regulates the H(+)-ATPase Pma1p; induced by heat shock, ethanol treatment, weak organic acid, glucose limitation, and entry into stationary phase |
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| YJL133C-A Show fit | 2.25 |
Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies |
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| YKL016C Show fit | 2.19 |
Subunit d of the stator stalk of mitochondrial F1F0 ATP synthase, which is a large, evolutionarily conserved enzyme complex required for ATP synthesis |
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| YML089C Show fit | 2.07 |
Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data; expression induced by calcium shortage |
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| YJR095W Show fit | 1.99 |
Mitochondrial succinate-fumarate transporter, transports succinate into and fumarate out of the mitochondrion; required for ethanol and acetate utilization |
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| YJR115W Show fit | 1.98 |
Putative protein of unknown function |
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| YPR001W Show fit | 1.71 |
Dual specificity mitochondrial citrate and methylcitrate synthase; catalyzes the condensation of acetyl-CoA and oxaloacetate to form citrate and that of propionyl-CoA and oxaloacetate to form 2-methylcitrate |
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| YJR138W Show fit | 1.70 |
Protein of unknown function, green fluorescent protein (GFP)-fusion protein localizes to the vacuolar membrane |
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| YNL036W Show fit | 1.60 |
Carbonic anhydrase; poorly transcribed under aerobic conditions and at an undetectable level under anaerobic conditions; involved in non-classical protein export pathway |
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| YKL163W Show fit | 1.56 |
O-glycosylated covalently-bound cell wall protein required for cell wall stability; expression is cell cycle regulated, peaking in M/G1 and also subject to regulation by the cell integrity pathway |
Network of associatons between targets according to the STRING database.
First level regulatory network of TYE7
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.4 | 3.6 | GO:0006122 | mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122) |
| 0.2 | 3.1 | GO:0015986 | energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986) |
| 0.1 | 3.0 | GO:0000422 | mitophagy(GO:0000422) mitochondrion disassembly(GO:0061726) |
| 0.8 | 2.4 | GO:0032780 | negative regulation of ATPase activity(GO:0032780) |
| 0.1 | 2.2 | GO:0098656 | anion transmembrane transport(GO:0098656) |
| 0.7 | 2.0 | GO:0015740 | C4-dicarboxylate transport(GO:0015740) |
| 0.6 | 1.7 | GO:0019629 | propionate metabolic process(GO:0019541) propionate catabolic process(GO:0019543) short-chain fatty acid catabolic process(GO:0019626) propionate catabolic process, 2-methylcitrate cycle(GO:0019629) |
| 0.4 | 1.6 | GO:0015976 | carbon utilization(GO:0015976) |
| 0.2 | 1.6 | GO:0015758 | glucose transport(GO:0015758) |
| 0.1 | 1.6 | GO:0034087 | establishment of sister chromatid cohesion(GO:0034085) establishment of mitotic sister chromatid cohesion(GO:0034087) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 4.5 | GO:0005743 | mitochondrial inner membrane(GO:0005743) |
| 0.4 | 3.5 | GO:0005750 | mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275) |
| 0.0 | 3.5 | GO:0005886 | plasma membrane(GO:0005886) |
| 0.1 | 2.5 | GO:0031225 | anchored component of membrane(GO:0031225) |
| 0.7 | 2.2 | GO:0000274 | mitochondrial proton-transporting ATP synthase, stator stalk(GO:0000274) proton-transporting ATP synthase, stator stalk(GO:0045265) |
| 0.0 | 2.0 | GO:0005758 | mitochondrial intermembrane space(GO:0005758) |
| 0.4 | 1.8 | GO:0030062 | mitochondrial tricarboxylic acid cycle enzyme complex(GO:0030062) |
| 0.4 | 1.7 | GO:0097042 | extrinsic component of fungal-type vacuolar membrane(GO:0097042) |
| 0.3 | 1.5 | GO:0032777 | Piccolo NuA4 histone acetyltransferase complex(GO:0032777) |
| 0.0 | 1.3 | GO:0031966 | mitochondrial membrane(GO:0031966) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 3.1 | GO:0046933 | proton-transporting ATP synthase activity, rotational mechanism(GO:0046933) |
| 0.4 | 2.8 | GO:0016681 | ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681) |
| 0.2 | 2.3 | GO:0005216 | ion channel activity(GO:0005216) |
| 0.1 | 2.1 | GO:0004402 | histone acetyltransferase activity(GO:0004402) peptide-lysine-N-acetyltransferase activity(GO:0061733) |
| 0.7 | 2.0 | GO:0004108 | citrate (Si)-synthase activity(GO:0004108) citrate synthase activity(GO:0036440) |
| 0.5 | 2.0 | GO:0015556 | C4-dicarboxylate transmembrane transporter activity(GO:0015556) |
| 0.4 | 1.8 | GO:0000099 | sulfur amino acid transmembrane transporter activity(GO:0000099) |
| 0.3 | 1.7 | GO:0005315 | inorganic phosphate transmembrane transporter activity(GO:0005315) |
| 0.0 | 1.7 | GO:0001228 | transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077) transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228) |
| 0.4 | 1.6 | GO:0004396 | hexokinase activity(GO:0004396) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 19.6 | ST GRANULE CELL SURVIVAL PATHWAY | Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway. |
| 0.2 | 0.8 | PID P73PATHWAY | p73 transcription factor network |
| 0.2 | 0.6 | PID EPHA2 FWD PATHWAY | EPHA2 forward signaling |
| 0.1 | 0.6 | PID FANCONI PATHWAY | Fanconi anemia pathway |
| 0.1 | 0.2 | PID TCR PATHWAY | TCR signaling in naïve CD4+ T cells |
| 0.1 | 0.2 | PID AR PATHWAY | Coregulation of Androgen receptor activity |
| 0.1 | 0.2 | PID NOTCH PATHWAY | Notch signaling pathway |
| 0.1 | 0.2 | PID P38 ALPHA BETA DOWNSTREAM PATHWAY | Signaling mediated by p38-alpha and p38-beta |
| 0.0 | 0.1 | NABA ECM REGULATORS | Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix |
| 0.0 | 0.0 | PID DELTA NP63 PATHWAY | Validated transcriptional targets of deltaNp63 isoforms |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 19.6 | REACTOME CHONDROITIN SULFATE BIOSYNTHESIS | Genes involved in Chondroitin sulfate biosynthesis |
| 0.1 | 1.1 | REACTOME DNA REPAIR | Genes involved in DNA Repair |
| 0.3 | 1.0 | REACTOME PYRUVATE METABOLISM AND CITRIC ACID TCA CYCLE | Genes involved in Pyruvate metabolism and Citric Acid (TCA) cycle |
| 0.2 | 1.0 | REACTOME BIOLOGICAL OXIDATIONS | Genes involved in Biological oxidations |
| 0.1 | 1.0 | REACTOME GLUCONEOGENESIS | Genes involved in Gluconeogenesis |
| 0.1 | 0.4 | REACTOME MEIOTIC SYNAPSIS | Genes involved in Meiotic Synapsis |
| 0.1 | 0.2 | REACTOME TRAF6 MEDIATED INDUCTION OF NFKB AND MAP KINASES UPON TLR7 8 OR 9 ACTIVATION | Genes involved in TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation |
| 0.0 | 0.1 | REACTOME TRANSMEMBRANE TRANSPORT OF SMALL MOLECULES | Genes involved in Transmembrane transport of small molecules |