Results for TEC1
Z-value: 1.52
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Transcription factors associated with TEC1
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
|
TEC1
|
S000000287 | Transcription factor targeting filamentation genes and Ty1 expression |
Activity-expression correlation:
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| YKR102W Show fit | 10.32 |
Lectin-like protein with similarity to Flo1p, thought to be involved in flocculation |
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| YAR053W Show fit | 7.77 |
Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data |
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| YOR382W Show fit | 7.58 |
Mannoprotein that is incorporated into the cell wall via a glycosylphosphatidylinositol (GPI) anchor, involved in the retention of siderophore-iron in the cell wall |
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| YKL217W Show fit | 7.05 |
Lactate transporter, required for uptake of lactate and pyruvate; phosphorylated; expression is derepressed by transcriptional activator Cat8p during respiratory growth, and repressed in the presence of glucose, fructose, and mannose |
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| YFL051C Show fit | 7.00 |
Putative protein of unknown function; YFL051C is not an essential gene |
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| YPR077C Show fit | 7.00 |
Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data; expression increased by deletion of NAP1 |
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| YER065C Show fit | 5.52 |
Isocitrate lyase, catalyzes the formation of succinate and glyoxylate from isocitrate, a key reaction of the glyoxylate cycle; expression of ICL1 is induced by growth on ethanol and repressed by growth on glucose |
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| YAR060C Show fit | 5.47 |
Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data |
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| YKL161C Show fit | 5.27 |
Protein kinase implicated in the Slt2p mitogen-activated (MAP) kinase signaling pathway; associates with Rlm1p |
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| YHR096C Show fit | 5.08 |
Hexose transporter with moderate affinity for glucose, induced in the presence of non-fermentable carbon sources, induced by a decrease in growth rate, contains an extended N-terminal domain relative to other HXTs |
Network of associatons between targets according to the STRING database.
First level regulatory network of TEC1
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 13.5 | GO:0009060 | aerobic respiration(GO:0009060) |
| 2.2 | 13.3 | GO:0000501 | flocculation(GO:0000128) flocculation via cell wall protein-carbohydrate interaction(GO:0000501) |
| 1.1 | 10.6 | GO:0046487 | glyoxylate metabolic process(GO:0046487) |
| 1.3 | 10.1 | GO:0015891 | siderophore transport(GO:0015891) |
| 0.5 | 8.7 | GO:0042724 | thiamine biosynthetic process(GO:0009228) thiamine-containing compound biosynthetic process(GO:0042724) |
| 1.8 | 7.0 | GO:0006848 | pyruvate transport(GO:0006848) |
| 0.2 | 5.7 | GO:0000422 | mitophagy(GO:0000422) mitochondrion disassembly(GO:0061726) |
| 0.6 | 5.5 | GO:0009746 | response to hexose(GO:0009746) response to glucose(GO:0009749) response to monosaccharide(GO:0034284) |
| 0.6 | 5.5 | GO:0006616 | SRP-dependent cotranslational protein targeting to membrane, translocation(GO:0006616) |
| 1.3 | 5.2 | GO:0043901 | negative regulation of conjugation(GO:0031135) negative regulation of conjugation with cellular fusion(GO:0031138) negative regulation of multi-organism process(GO:0043901) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 7.8 | GO:0005886 | plasma membrane(GO:0005886) |
| 0.3 | 7.3 | GO:0000932 | cytoplasmic mRNA processing body(GO:0000932) |
| 0.1 | 6.6 | GO:0005743 | mitochondrial inner membrane(GO:0005743) |
| 0.1 | 6.3 | GO:0042579 | peroxisome(GO:0005777) microbody(GO:0042579) |
| 0.0 | 5.2 | GO:0000329 | fungal-type vacuole membrane(GO:0000329) lytic vacuole membrane(GO:0098852) |
| 0.4 | 4.8 | GO:0005619 | ascospore wall(GO:0005619) |
| 0.2 | 4.8 | GO:0005887 | integral component of plasma membrane(GO:0005887) |
| 1.6 | 4.7 | GO:0031422 | RecQ helicase-Topo III complex(GO:0031422) |
| 1.4 | 4.3 | GO:0045269 | mitochondrial proton-transporting ATP synthase, central stalk(GO:0005756) proton-transporting ATP synthase, central stalk(GO:0045269) |
| 1.0 | 4.0 | GO:0031315 | extrinsic component of mitochondrial outer membrane(GO:0031315) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 3.5 | 14.1 | GO:0005537 | mannose binding(GO:0005537) |
| 1.9 | 9.6 | GO:0015295 | solute:proton symporter activity(GO:0015295) |
| 0.1 | 8.9 | GO:0004674 | protein serine/threonine kinase activity(GO:0004674) |
| 0.6 | 8.6 | GO:0001135 | transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135) |
| 0.1 | 8.6 | GO:0051082 | unfolded protein binding(GO:0051082) |
| 0.3 | 7.1 | GO:0016209 | antioxidant activity(GO:0016209) |
| 0.2 | 6.1 | GO:0003684 | damaged DNA binding(GO:0003684) |
| 0.8 | 5.5 | GO:0016833 | oxo-acid-lyase activity(GO:0016833) |
| 0.2 | 5.2 | GO:0016881 | acid-amino acid ligase activity(GO:0016881) |
| 0.6 | 5.1 | GO:0038023 | transmembrane signaling receptor activity(GO:0004888) signaling receptor activity(GO:0038023) transmembrane receptor activity(GO:0099600) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 142.3 | PID P53 DOWNSTREAM PATHWAY | Direct p53 effectors |
| 0.6 | 4.9 | PID FANCONI PATHWAY | Fanconi anemia pathway |
| 0.7 | 2.9 | PID DELTA NP63 PATHWAY | Validated transcriptional targets of deltaNp63 isoforms |
| 0.3 | 2.1 | PID MYC ACTIV PATHWAY | Validated targets of C-MYC transcriptional activation |
| 0.8 | 1.6 | PID RB 1PATHWAY | Regulation of retinoblastoma protein |
| 0.5 | 1.6 | PID AP1 PATHWAY | AP-1 transcription factor network |
| 0.4 | 1.1 | PID TCR PATHWAY | TCR signaling in naïve CD4+ T cells |
| 0.3 | 0.8 | PID TELOMERASE PATHWAY | Regulation of Telomerase |
| 0.4 | 0.4 | ST INTEGRIN SIGNALING PATHWAY | Integrin Signaling Pathway |
| 0.1 | 0.3 | NABA ECM REGULATORS | Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 138.1 | REACTOME CHONDROITIN SULFATE BIOSYNTHESIS | Genes involved in Chondroitin sulfate biosynthesis |
| 0.5 | 5.1 | REACTOME DNA REPAIR | Genes involved in DNA Repair |
| 0.4 | 1.9 | REACTOME DIABETES PATHWAYS | Genes involved in Diabetes pathways |
| 0.2 | 1.6 | REACTOME MEIOTIC RECOMBINATION | Genes involved in Meiotic Recombination |
| 0.3 | 1.5 | REACTOME METABOLISM OF POLYAMINES | Genes involved in Metabolism of polyamines |
| 0.4 | 1.3 | REACTOME SHC1 EVENTS IN ERBB4 SIGNALING | Genes involved in SHC1 events in ERBB4 signaling |
| 0.4 | 1.1 | REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS | Genes involved in Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. |
| 0.1 | 1.0 | REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX | Genes involved in CDC6 association with the ORC:origin complex |
| 0.3 | 0.8 | REACTOME TELOMERE MAINTENANCE | Genes involved in Telomere Maintenance |
| 0.1 | 0.6 | REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS | Genes involved in Apoptotic cleavage of cellular proteins |