Results for TBF1
Z-value: 0.67
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Transcription factors associated with TBF1
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
|
TBF1
|
S000006049 | Telobox-containing general regulatory factor |
Activity-expression correlation:
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| YLR312C Show fit | 2.19 |
Protein of unknown function; null mutant quiescent and non-quiescent cells exhibit reduced reproductive capacity |
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| YHR212W-A Show fit | 1.52 |
Putative protein of unknown function; identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching |
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| YMR107W Show fit | 1.51 |
Protein required for survival at high temperature during stationary phase; not required for growth on nonfermentable carbon sources |
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| YAR053W Show fit | 1.41 |
Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data |
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| YJL133C-A Show fit | 1.31 |
Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies |
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| YCR068W Show fit | 1.26 |
Lipase, required for intravacuolar lysis of autophagosomes; located in the endoplasmic reticulum membrane and targeted to intravacuolar vesicles during autophagy via the multivesicular body (MVB) pathway |
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| YDR490C Show fit | 1.09 |
Serine/threonine protein kinase involved in sphingolipid-mediated signaling pathway that controls endocytosis; activates Ypk1p and Ykr2p, components of signaling cascade required for maintenance of cell wall integrity; redundant with Pkh2p |
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| YFL033C Show fit | 1.06 |
Glucose-repressible protein kinase involved in signal transduction during cell proliferation in response to nutrients, specifically the establishment of stationary phase; identified as a regulator of IME2; substrate of Pho80p-Pho85p kinase |
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| YGL146C Show fit | 1.04 |
Putative protein of unknown function, contains two putative transmembrane spans, shows no significant homology to any other known protein sequence, YGL146C is not an essential gene |
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| YKL171W Show fit | 1.04 |
Putative protein of unknown function; predicted protein kinase; implicated in proteasome function; epitope-tagged protein localizes to the cytoplasm |
Network of associatons between targets according to the STRING database.
First level regulatory network of TBF1
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 2.2 | GO:0006097 | glyoxylate cycle(GO:0006097) |
| 0.4 | 1.7 | GO:0008214 | protein demethylation(GO:0006482) protein dealkylation(GO:0008214) histone demethylation(GO:0016577) demethylation(GO:0070988) |
| 0.1 | 1.6 | GO:0008535 | respiratory chain complex IV assembly(GO:0008535) |
| 0.3 | 1.5 | GO:0060211 | regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060211) |
| 0.4 | 1.3 | GO:0036257 | multivesicular body organization(GO:0036257) |
| 0.2 | 1.3 | GO:0071472 | cellular response to salt stress(GO:0071472) |
| 0.1 | 1.3 | GO:0031321 | ascospore-type prospore assembly(GO:0031321) |
| 0.4 | 1.2 | GO:0000304 | response to singlet oxygen(GO:0000304) |
| 0.3 | 1.2 | GO:0006848 | pyruvate transport(GO:0006848) |
| 0.2 | 1.2 | GO:0046464 | triglyceride catabolic process(GO:0019433) neutral lipid catabolic process(GO:0046461) acylglycerol catabolic process(GO:0046464) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 1.9 | GO:0031907 | peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907) |
| 0.2 | 1.5 | GO:0032126 | eisosome(GO:0032126) |
| 0.4 | 1.3 | GO:0032585 | multivesicular body membrane(GO:0032585) |
| 0.1 | 1.2 | GO:0016592 | mediator complex(GO:0016592) |
| 0.1 | 1.0 | GO:0031304 | intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305) |
| 0.2 | 0.9 | GO:0032865 | ERMES complex(GO:0032865) ER-mitochondrion membrane contact site(GO:0044233) |
| 0.0 | 0.9 | GO:0042764 | prospore membrane(GO:0005628) intracellular immature spore(GO:0042763) ascospore-type prospore(GO:0042764) |
| 0.0 | 0.8 | GO:0005680 | anaphase-promoting complex(GO:0005680) |
| 0.0 | 0.8 | GO:0000124 | SAGA complex(GO:0000124) |
| 0.1 | 0.7 | GO:0005880 | nuclear microtubule(GO:0005880) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 3.0 | GO:0004674 | protein serine/threonine kinase activity(GO:0004674) |
| 0.5 | 2.4 | GO:0050253 | triglyceride lipase activity(GO:0004806) retinyl-palmitate esterase activity(GO:0050253) |
| 0.0 | 2.1 | GO:0004842 | ubiquitin-protein transferase activity(GO:0004842) |
| 0.5 | 1.8 | GO:0000156 | phosphorelay response regulator activity(GO:0000156) |
| 0.4 | 1.7 | GO:0032452 | histone demethylase activity(GO:0032452) |
| 0.2 | 1.2 | GO:0015295 | solute:proton symporter activity(GO:0015295) |
| 0.0 | 1.1 | GO:0004721 | phosphoprotein phosphatase activity(GO:0004721) |
| 0.0 | 1.1 | GO:0003729 | mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822) |
| 0.2 | 1.0 | GO:0005537 | mannose binding(GO:0005537) |
| 0.1 | 1.0 | GO:0046912 | transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 0.8 | PID DELTA NP63 PATHWAY | Validated transcriptional targets of deltaNp63 isoforms |
| 0.0 | 0.4 | PID FANCONI PATHWAY | Fanconi anemia pathway |
| 0.1 | 0.3 | PID ANGIOPOIETIN RECEPTOR PATHWAY | Angiopoietin receptor Tie2-mediated signaling |
| 0.1 | 0.2 | SA G1 AND S PHASES | Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition. |
| 0.0 | 0.2 | PID ATR PATHWAY | ATR signaling pathway |
| 0.0 | 0.2 | PID ERA GENOMIC PATHWAY | Validated nuclear estrogen receptor alpha network |
| 0.0 | 0.1 | ST DIFFERENTIATION PATHWAY IN PC12 CELLS | Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway. |
| 0.0 | 0.1 | PID P53 DOWNSTREAM PATHWAY | Direct p53 effectors |
| 0.0 | 0.1 | PID P73PATHWAY | p73 transcription factor network |
| 0.0 | 0.1 | PID FOXO PATHWAY | FoxO family signaling |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 0.5 | REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION | Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression |
| 0.1 | 0.4 | REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S | Genes involved in Activation of Chaperone Genes by XBP1(S) |
| 0.1 | 0.3 | REACTOME PHOSPHORYLATION OF THE APC C | Genes involved in Phosphorylation of the APC/C |
| 0.1 | 0.2 | REACTOME MEIOTIC SYNAPSIS | Genes involved in Meiotic Synapsis |
| 0.0 | 0.2 | REACTOME METABOLISM OF POLYAMINES | Genes involved in Metabolism of polyamines |
| 0.0 | 0.2 | REACTOME MITOCHONDRIAL PROTEIN IMPORT | Genes involved in Mitochondrial Protein Import |
| 0.0 | 0.2 | REACTOME MEIOTIC RECOMBINATION | Genes involved in Meiotic Recombination |
| 0.0 | 0.1 | REACTOME G1 S SPECIFIC TRANSCRIPTION | Genes involved in G1/S-Specific Transcription |
| 0.0 | 0.1 | REACTOME NGF SIGNALLING VIA TRKA FROM THE PLASMA MEMBRANE | Genes involved in NGF signalling via TRKA from the plasma membrane |
| 0.0 | 0.1 | REACTOME MRNA 3 END PROCESSING | Genes involved in mRNA 3'-end processing |