Results for STP4
Z-value: 2.90
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Transcription factors associated with STP4
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
|
STP4
|
S000002206 | Protein containing a Kruppel-type zinc-finger domain |
Activity-expression correlation:
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| YMR107W Show fit | 37.42 |
Protein required for survival at high temperature during stationary phase; not required for growth on nonfermentable carbon sources |
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| YOR100C Show fit | 33.56 |
Mitochondrial inner membrane carnitine transporter, required for carnitine-dependent transport of acetyl-CoA from peroxisomes to mitochondria during fatty acid beta-oxidation |
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| YLR307C-A Show fit | 32.06 |
Putative protein of unknown function |
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| YIL057C Show fit | 31.08 |
Putative protein of unknown function; expression induced under carbon limitation and repressed under high glucose |
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| YCR010C Show fit | 25.48 |
Acetate transporter required for normal sporulation; phosphorylated in mitochondria |
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| YKR097W Show fit | 24.42 |
Phosphoenolpyruvate carboxykinase, key enzyme in gluconeogenesis, catalyzes early reaction in carbohydrate biosynthesis, glucose represses transcription and accelerates mRNA degradation, regulated by Mcm1p and Cat8p, located in the cytosol |
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| YJL045W Show fit | 23.26 |
Minor succinate dehydrogenase isozyme; homologous to Sdh1p, the major isozyme reponsible for the oxidation of succinate and transfer of electrons to ubiquinone; induced during the diauxic shift in a Cat8p-dependent manner |
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| YNR002C Show fit | 23.14 |
Putative transmembrane protein involved in export of ammonia, a starvation signal that promotes cell death in aging colonies; phosphorylated in mitochondria; member of the TC 9.B.33 YaaH family; homolog of Ady2p and Y. lipolytica Gpr1p |
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| YAL054C Show fit | 21.11 |
Acetyl-coA synthetase isoform which, along with Acs2p, is the nuclear source of acetyl-coA for histone acetlyation; expressed during growth on nonfermentable carbon sources and under aerobic conditions |
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| YOR382W Show fit | 20.97 |
Mannoprotein that is incorporated into the cell wall via a glycosylphosphatidylinositol (GPI) anchor, involved in the retention of siderophore-iron in the cell wall |
Network of associatons between targets according to the STRING database.
First level regulatory network of STP4
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 2.8 | 61.6 | GO:0019740 | nitrogen utilization(GO:0019740) |
| 7.3 | 29.3 | GO:0006848 | pyruvate transport(GO:0006848) |
| 1.3 | 27.1 | GO:0000209 | protein polyubiquitination(GO:0000209) |
| 3.4 | 27.0 | GO:0015891 | siderophore transport(GO:0015891) |
| 4.1 | 24.4 | GO:0000128 | flocculation(GO:0000128) flocculation via cell wall protein-carbohydrate interaction(GO:0000501) |
| 3.0 | 23.8 | GO:0006097 | glyoxylate cycle(GO:0006097) |
| 1.4 | 23.0 | GO:0009228 | thiamine biosynthetic process(GO:0009228) thiamine-containing compound biosynthetic process(GO:0042724) |
| 1.4 | 22.7 | GO:0006754 | ATP biosynthetic process(GO:0006754) |
| 0.9 | 22.6 | GO:0006094 | gluconeogenesis(GO:0006094) |
| 7.4 | 22.1 | GO:0006577 | amino-acid betaine metabolic process(GO:0006577) carnitine metabolic process(GO:0009437) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.4 | 74.6 | GO:0005743 | mitochondrial inner membrane(GO:0005743) |
| 1.0 | 53.8 | GO:0005777 | peroxisome(GO:0005777) microbody(GO:0042579) |
| 0.1 | 45.0 | GO:0005739 | mitochondrion(GO:0005739) |
| 0.8 | 35.5 | GO:0031225 | anchored component of membrane(GO:0031225) |
| 0.2 | 29.3 | GO:0005774 | vacuolar membrane(GO:0005774) |
| 0.9 | 22.4 | GO:0042764 | prospore membrane(GO:0005628) intracellular immature spore(GO:0042763) ascospore-type prospore(GO:0042764) |
| 1.4 | 16.5 | GO:0005782 | peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907) |
| 0.5 | 15.9 | GO:0000322 | storage vacuole(GO:0000322) lytic vacuole(GO:0000323) fungal-type vacuole(GO:0000324) |
| 0.3 | 15.4 | GO:0000502 | proteasome complex(GO:0000502) |
| 3.8 | 15.2 | GO:0030287 | cell wall-bounded periplasmic space(GO:0030287) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.0 | 46.7 | GO:0001077 | transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077) transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228) |
| 3.1 | 34.5 | GO:0008028 | monocarboxylic acid transmembrane transporter activity(GO:0008028) |
| 6.0 | 30.1 | GO:0015295 | solute:proton symporter activity(GO:0015295) |
| 8.9 | 26.6 | GO:0036440 | citrate (Si)-synthase activity(GO:0004108) citrate synthase activity(GO:0036440) |
| 6.1 | 24.4 | GO:0005537 | mannose binding(GO:0005537) |
| 2.7 | 24.4 | GO:0008519 | ammonium transmembrane transporter activity(GO:0008519) |
| 1.0 | 23.5 | GO:0016881 | acid-amino acid ligase activity(GO:0016881) |
| 7.4 | 22.1 | GO:0016406 | carnitine O-acetyltransferase activity(GO:0004092) carnitine O-acyltransferase activity(GO:0016406) |
| 7.0 | 21.1 | GO:0016208 | AMP binding(GO:0016208) |
| 1.3 | 20.5 | GO:0016831 | carboxy-lyase activity(GO:0016831) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 368.6 | PID NFAT 3PATHWAY | Role of Calcineurin-dependent NFAT signaling in lymphocytes |
| 8.1 | 24.4 | PID HNF3B PATHWAY | FOXA2 and FOXA3 transcription factor networks |
| 0.9 | 8.0 | PID FANCONI PATHWAY | Fanconi anemia pathway |
| 1.2 | 7.4 | PID MYC ACTIV PATHWAY | Validated targets of C-MYC transcriptional activation |
| 0.9 | 2.8 | PID TCR PATHWAY | TCR signaling in naïve CD4+ T cells |
| 0.9 | 2.6 | NABA ECM REGULATORS | Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix |
| 0.4 | 1.8 | PID P73PATHWAY | p73 transcription factor network |
| 0.4 | 1.2 | PID AR PATHWAY | Coregulation of Androgen receptor activity |
| 0.3 | 0.7 | PID ANGIOPOIETIN RECEPTOR PATHWAY | Angiopoietin receptor Tie2-mediated signaling |
| 0.1 | 0.4 | SA G1 AND S PHASES | Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition. |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 368.6 | REACTOME CHONDROITIN SULFATE BIOSYNTHESIS | Genes involved in Chondroitin sulfate biosynthesis |
| 3.0 | 23.7 | REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION | Genes involved in Transcriptional Regulation of White Adipocyte Differentiation |
| 1.2 | 4.7 | REACTOME DOUBLE STRAND BREAK REPAIR | Genes involved in Double-Strand Break Repair |
| 0.5 | 3.5 | REACTOME MEIOTIC RECOMBINATION | Genes involved in Meiotic Recombination |
| 0.5 | 2.7 | REACTOME METABOLISM OF POLYAMINES | Genes involved in Metabolism of polyamines |
| 0.8 | 2.5 | REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S | Genes involved in Activation of Chaperone Genes by XBP1(S) |
| 0.5 | 1.6 | REACTOME SIGNALING BY NOTCH1 | Genes involved in Signaling by NOTCH1 |
| 0.3 | 0.8 | REACTOME ETHANOL OXIDATION | Genes involved in Ethanol oxidation |
| 0.2 | 0.7 | REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE | Genes involved in Synthesis of PIPs at the early endosome membrane |
| 0.1 | 0.6 | REACTOME MITOTIC PROMETAPHASE | Genes involved in Mitotic Prometaphase |