Results for STP3
Z-value: 1.44
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Transcription factors associated with STP3
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
|
STP3
|
S000004367 | Zinc-finger protein of unknown function |
Activity-expression correlation:
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| YMR107W Show fit | 24.48 |
Protein required for survival at high temperature during stationary phase; not required for growth on nonfermentable carbon sources |
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| YDR536W Show fit | 9.73 |
Glycerol proton symporter of the plasma membrane, subject to glucose-induced inactivation, strongly but transiently induced when cells are subjected to osmotic shock |
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| YLR327C Show fit | 8.60 |
Protein of unknown function that associates with ribosomes |
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| YLR122C Show fit | 8.11 |
Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the dubious ORF YLR123C |
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| YIL160C Show fit | 7.53 |
3-ketoacyl-CoA thiolase with broad chain length specificity, cleaves 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA during beta-oxidation of fatty acids |
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| YLR402W Show fit | 7.41 |
Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data |
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| YMR206W Show fit | 7.41 |
Putative protein of unknown function; YMR206W is not an essential gene |
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| YLR403W Show fit | 7.20 |
Transcription factor that controls expression of many ribosome biogenesis genes in response to nutrients and stress, regulates G2/M transitions during mitotic cell cycle and DNA-damage response, involved in cell size modulation |
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| YOR348C Show fit | 7.16 |
Proline permease, required for high-affinity transport of proline; also transports the toxic proline analog azetidine-2-carboxylate (AzC); PUT4 transcription is repressed in ammonia-grown cells |
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| YDL169C Show fit | 7.03 |
Protein of unknown function, transcript accumulates in response to any combination of stress conditions |
Network of associatons between targets according to the STRING database.
First level regulatory network of STP3
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.4 | 13.8 | GO:0006122 | mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122) |
| 0.6 | 13.6 | GO:0098656 | anion transmembrane transport(GO:0098656) |
| 2.4 | 9.4 | GO:0015804 | neutral amino acid transport(GO:0015804) |
| 1.0 | 9.3 | GO:0070086 | ubiquitin-dependent endocytosis(GO:0070086) |
| 1.7 | 8.6 | GO:0015793 | glycerol transport(GO:0015793) |
| 0.3 | 8.0 | GO:0022900 | electron transport chain(GO:0022900) |
| 1.0 | 7.8 | GO:0008614 | pyridoxine metabolic process(GO:0008614) pyridoxine biosynthetic process(GO:0008615) vitamin B6 metabolic process(GO:0042816) vitamin B6 biosynthetic process(GO:0042819) |
| 1.1 | 7.6 | GO:0000255 | allantoin metabolic process(GO:0000255) allantoin catabolic process(GO:0000256) |
| 1.2 | 7.0 | GO:0009102 | biotin metabolic process(GO:0006768) biotin biosynthetic process(GO:0009102) |
| 1.7 | 6.9 | GO:0006527 | arginine catabolic process(GO:0006527) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 30.2 | GO:0005743 | mitochondrial inner membrane(GO:0005743) |
| 0.1 | 15.3 | GO:0005886 | plasma membrane(GO:0005886) |
| 0.0 | 14.6 | GO:0005739 | mitochondrion(GO:0005739) |
| 1.2 | 10.6 | GO:0005750 | mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275) |
| 0.1 | 9.4 | GO:0000324 | storage vacuole(GO:0000322) lytic vacuole(GO:0000323) fungal-type vacuole(GO:0000324) |
| 0.5 | 8.4 | GO:0070469 | respiratory chain(GO:0070469) |
| 0.6 | 6.7 | GO:0031907 | peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907) |
| 0.1 | 5.3 | GO:0031225 | anchored component of membrane(GO:0031225) |
| 0.1 | 4.7 | GO:0090575 | RNA polymerase II transcription factor complex(GO:0090575) |
| 0.8 | 4.1 | GO:0034448 | EGO complex(GO:0034448) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 3.6 | 18.1 | GO:0015295 | solute:proton symporter activity(GO:0015295) |
| 3.5 | 13.9 | GO:0015193 | L-proline transmembrane transporter activity(GO:0015193) |
| 0.8 | 13.2 | GO:0020037 | heme binding(GO:0020037) tetrapyrrole binding(GO:0046906) |
| 0.6 | 11.4 | GO:0008483 | transaminase activity(GO:0008483) transferase activity, transferring nitrogenous groups(GO:0016769) |
| 0.4 | 11.3 | GO:0016811 | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides(GO:0016811) |
| 0.2 | 11.2 | GO:0051082 | unfolded protein binding(GO:0051082) |
| 0.3 | 10.7 | GO:0001076 | transcription factor activity, RNA polymerase II transcription factor binding(GO:0001076) |
| 1.0 | 8.8 | GO:0016723 | ferric-chelate reductase activity(GO:0000293) oxidoreductase activity, oxidizing metal ions, NAD or NADP as acceptor(GO:0016723) |
| 1.0 | 7.9 | GO:0016681 | ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681) |
| 1.3 | 7.8 | GO:0090599 | alpha-glucosidase activity(GO:0090599) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 140.5 | PID TELOMERASE PATHWAY | Regulation of Telomerase |
| 0.4 | 3.4 | PID FANCONI PATHWAY | Fanconi anemia pathway |
| 0.7 | 2.0 | PID IL4 2PATHWAY | IL4-mediated signaling events |
| 0.3 | 1.7 | PID MYC ACTIV PATHWAY | Validated targets of C-MYC transcriptional activation |
| 0.2 | 0.7 | PID P53 DOWNSTREAM PATHWAY | Direct p53 effectors |
| 0.2 | 0.4 | PID ANGIOPOIETIN RECEPTOR PATHWAY | Angiopoietin receptor Tie2-mediated signaling |
| 0.2 | 0.3 | ST DIFFERENTIATION PATHWAY IN PC12 CELLS | Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway. |
| 0.1 | 0.3 | PID HNF3B PATHWAY | FOXA2 and FOXA3 transcription factor networks |
| 0.1 | 0.3 | PID FOXO PATHWAY | FoxO family signaling |
| 0.1 | 0.1 | PID RET PATHWAY | Signaling events regulated by Ret tyrosine kinase |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 133.0 | REACTOME CHONDROITIN SULFATE BIOSYNTHESIS | Genes involved in Chondroitin sulfate biosynthesis |
| 2.8 | 8.3 | REACTOME MEIOTIC SYNAPSIS | Genes involved in Meiotic Synapsis |
| 0.4 | 5.0 | REACTOME DNA REPAIR | Genes involved in DNA Repair |
| 1.2 | 3.5 | REACTOME RESPIRATORY ELECTRON TRANSPORT | Genes involved in Respiratory electron transport |
| 0.1 | 0.9 | REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES | Genes involved in Metabolism of amino acids and derivatives |
| 0.2 | 0.8 | REACTOME BIOLOGICAL OXIDATIONS | Genes involved in Biological oxidations |
| 0.1 | 0.7 | REACTOME MEIOTIC RECOMBINATION | Genes involved in Meiotic Recombination |
| 0.1 | 0.4 | REACTOME TRANSMEMBRANE TRANSPORT OF SMALL MOLECULES | Genes involved in Transmembrane transport of small molecules |
| 0.2 | 0.3 | REACTOME TRAF6 MEDIATED INDUCTION OF NFKB AND MAP KINASES UPON TLR7 8 OR 9 ACTIVATION | Genes involved in TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation |
| 0.1 | 0.2 | REACTOME NETRIN1 SIGNALING | Genes involved in Netrin-1 signaling |