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Results for STB3

Z-value: 8.90

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Transcription factors associated with STB3

Gene Symbol Gene ID Gene Info
STB3
S000002576 Ribosomal RNA processing element (RRPE)-binding protein

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
STB3YDR169C-0.706.1e-05Click!

Activity profile of STB3 motif

Sorted Z-values of STB3 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
YFR055W 118.28
IRC7
Putative cystathionine beta-lyase; involved in copper ion homeostasis and sulfur metabolism; null mutant displays increased levels of spontaneous Rad52p foci; expression induced by nitrogen limitation in a GLN3, GAT1-dependent manner
YFR056C 104.97 Dubious open reading frame unlikely to encode a protein based on available experimental and comparative sequence data; partially overlaps the uncharacterized gene YFR055W
YOR063W 79.60
RPL3
Protein component of the large (60S) ribosomal subunit, has similarity to E. coli L3 and rat L3 ribosomal proteins; involved in the replication and maintenance of killer double stranded RNA virus
YML056C 70.44
IMD4
Inosine monophosphate dehydrogenase, catalyzes the first step of GMP biosynthesis, member of a four-gene family in S. cerevisiae, constitutively expressed
YIL009W 61.49
FAA3
Long chain fatty acyl-CoA synthetase, has a preference for C16 and C18 fatty acids; green fluorescent protein (GFP)-fusion protein localizes to the cell periphery
YJR094W-A 52.61
RPL43B
Protein component of the large (60S) ribosomal subunit, identical to Rpl43Ap and has similarity to rat L37a ribosomal protein
YGR108W 51.86
CLB1
B-type cyclin involved in cell cycle progression; activates Cdc28p to promote the transition from G2 to M phase; accumulates during G2 and M, then targeted via a destruction box motif for ubiquitin-mediated degradation by the proteasome
YIL009C-A 51.10
EST3
Component of the telomerase holoenzyme, involved in telomere replication
YLR029C 48.51
RPL15A
Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl15Bp and has similarity to rat L15 ribosomal protein; binds to 5.8 S rRNA
YHR010W 47.38
RPL27A
Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl27Bp and has similarity to rat L27 ribosomal protein
YEL068C 47.07 Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data
YMR049C 46.30
ERB1
Protein required for maturation of the 25S and 5.8S ribosomal RNAs; constituent of 66S pre-ribosomal particles; homologous to mammalian Bop1
YOR101W 45.84
RAS1
GTPase involved in G-protein signaling in the adenylate cyclase activating pathway, plays a role in cell proliferation; localized to the plasma membrane; homolog of mammalian RAS proto-oncogenes
YGR159C 42.85
NSR1
Nucleolar protein that binds nuclear localization sequences, required for pre-rRNA processing and ribosome biogenesis
YBR092C 42.69
PHO3
Constitutively expressed acid phosphatase similar to Pho5p; brought to the cell surface by transport vesicles; hydrolyzes thiamin phosphates in the periplasmic space, increasing cellular thiamin uptake; expression is repressed by thiamin
YCR034W 42.23
FEN1
Fatty acid elongase, involved in sphingolipid biosynthesis; acts on fatty acids of up to 24 carbons in length; mutations have regulatory effects on 1,3-beta-glucan synthase, vacuolar ATPase, and the secretory pathway
YNL178W 40.96
RPS3
Protein component of the small (40S) ribosomal subunit, has apurinic/apyrimidinic (AP) endonuclease activity; essential for viability; has similarity to E. coli S3 and rat S3 ribosomal proteins
YDR033W 40.85
MRH1
Protein that localizes primarily to the plasma membrane, also found at the nuclear envelope; the authentic, non-tagged protein is detected in mitochondria in a phosphorylated state; has similarity to Hsp30p and Yro2p
YJL011C 39.70
RPC17
RNA polymerase III subunit C17; physically interacts with C31, C11, and TFIIIB70; may be involved in the recruitment of pol III by the preinitiation complex
YDL136W 38.91
RPL35B
Protein component of the large (60S) ribosomal subunit, identical to Rpl35Ap and has similarity to rat L35 ribosomal protein
YBR158W 38.49
AMN1
Protein required for daughter cell separation, multiple mitotic checkpoints, and chromosome stability; contains 12 degenerate leucine-rich repeat motifs; expression is induced by the Mitotic Exit Network (MEN)
YEL066W 37.48
HPA3
D-Amino acid N-acetyltransferase, catalyzes N-acetylation of D-amino acids through ordered bi-bi mechanism in which acetyl-CoA is first substrate bound and CoA is last product liberated; similar to Hpa2p, acetylates histones weakly in vitro
YOR376W-A 36.54 Putative protein of unknown function; identified by fungal homology and RT-PCR
YKR092C 36.47
SRP40
Nucleolar, serine-rich protein with a role in preribosome assembly or transport; may function as a chaperone of small nucleolar ribonucleoprotein particles (snoRNPs); immunologically and structurally to rat Nopp140
YHR208W 36.23
BAT1
Mitochondrial branched-chain amino acid aminotransferase, homolog of murine ECA39; highly expressed during logarithmic phase and repressed during stationary phase
YMR217W 35.58
GUA1
GMP synthase, an enzyme that catalyzes the second step in the biosynthesis of GMP from inosine 5'-phosphate (IMP); transcription is not subject to regulation by guanine but is negatively regulated by nutrient starvation
YBR249C 35.42
ARO4
3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP) synthase, catalyzes the first step in aromatic amino acid biosynthesis and is feedback-inhibited by tyrosine or high concentrations of phenylalanine or tryptophan
YDL167C 35.19
NRP1
Protein of unknown function, rich in asparagine residues
YDR279W 34.75
RNH202
Ribonuclease H2 subunit, required for RNase H2 activity
YOR051C 34.62 Nuclear protein that inhibits replication of Brome mosaic virus in S. cerevisiae, which is a model system for studying replication of positive-strand RNA viruses in their natural hosts
YOR342C 34.48 Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and the nucleus
YOR198C 34.39
BFR1
Component of mRNP complexes associated with polyribosomes; implicated in secretion and nuclear segregation; multicopy suppressor of BFA (Brefeldin A) sensitivity
YNR053C 34.17
NOG2
Putative GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation
YLR325C 33.94
RPL38
Protein component of the large (60S) ribosomal subunit, has similarity to rat L38 ribosomal protein
YIR021W 33.42
MRS1
Protein required for the splicing of two mitochondrial group I introns (BI3 in COB and AI5beta in COX1); forms a splicing complex, containing four subunits of Mrs1p and two subunits of the BI3-encoded maturase, that binds to the BI3 RNA
YFR054C 32.32 Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data
YPL183C 32.13
RTT10
Cytoplasmic protein with a role in regulation of Ty1 transposition
YPR119W 31.95
CLB2
B-type cyclin involved in cell cycle progression; activates Cdc28p to promote the transition from G2 to M phase; accumulates during G2 and M, then targeted via a destruction box motif for ubiquitin-mediated degradation by the proteasome
YDR509W 31.25 Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data
YOR047C 31.19
STD1
Protein involved in control of glucose-regulated gene expression; interacts with protein kinase Snf1p, glucose sensors Snf3p and Rgt2p, and TATA-binding protein Spt15p; acts as a regulator of the transcription factor Rgt1p
YEL067C 31.17 Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies
YLR175W 31.12
CBF5
Pseudouridine synthase catalytic subunit of box H/ACA small nucleolar ribonucleoprotein particles (snoRNPs), acts on both large and small rRNAs and on snRNA U2
YEL027W 30.90
CUP5
Proteolipid subunit of the vacuolar H(+)-ATPase V0 sector (subunit c; dicyclohexylcarbodiimide binding subunit); required for vacuolar acidification and important for copper and iron metal ion homeostasis
YMR260C 30.64
TIF11
Translation initiation factor eIF1A, essential protein that forms a complex with Sui1p (eIF1) and the 40S ribosomal subunit and scans for the start codon; C-terminus associates with Fun12p (eIF5B); N terminus interacts with eIF2 and eIF3
YDR508C 30.51
GNP1
High-affinity glutamine permease, also transports Leu, Ser, Thr, Cys, Met and Asn; expression is fully dependent on Grr1p and modulated by the Ssy1p-Ptr3p-Ssy5p (SPS) sensor of extracellular amino acids
YOR375C 30.29
GDH1
NADP(+)-dependent glutamate dehydrogenase, synthesizes glutamate from ammonia and alpha-ketoglutarate; rate of alpha-ketoglutarate utilization differs from Gdh3p; expression regulated by nitrogen and carbon sources
YOR234C 29.93
RPL33B
Ribosomal protein L37 of the large (60S) ribosomal subunit, nearly identical to Rpl33Ap and has similarity to rat L35a; rpl33b null mutant exhibits normal growth while rpl33a rpl33b double null mutant is inviable
YLR197W 29.73
SIK1
Essential evolutionarily-conserved nucleolar protein component of the box C/D snoRNP complexes that direct 2'-O-methylation of pre-rRNA during its maturation; overexpression causes spindle orientation defects
YGL147C 29.67
RPL9A
Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl9Bp and has similarity to E. coli L6 and rat L9 ribosomal proteins
YGL076C 29.40
RPL7A
Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl7Bp and has similarity to E. coli L30 and rat L7 ribosomal proteins; contains a conserved C-terminal Nucleic acid Binding Domain (NDB2)
YJL190C 28.99
RPS22A
Protein component of the small (40S) ribosomal subunit; nearly identical to Rps22Bp and has similarity to E. coli S8 and rat S15a ribosomal proteins
YCR087C-A 28.98
LUG1
Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the nucleolus; YCR087C-A is not an essential gene
YGL179C 28.85
TOS3
Protein kinase, related to and functionally redundant with Elm1p and Sak1p for the phosphorylation and activation of Snf1p; functionally orthologous to LKB1, a mammalian kinase associated with Peutz-Jeghers cancer-susceptibility syndrome
YGL202W 28.75
ARO8
Aromatic aminotransferase I, expression is regulated by general control of amino acid biosynthesis
YOR310C 28.62
NOP58
Protein involved in pre-rRNA processing, 18S rRNA synthesis, and snoRNA synthesis; component of the small subunit processome complex, which is required for processing of pre-18S rRNA
YPL198W 28.36
RPL7B
Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl7Ap and has similarity to E. coli L30 and rat L7 ribosomal proteins; contains a conserved C-terminal Nucleic acid Binding Domain (NDB2)
YGL031C 27.77
RPL24A
Ribosomal protein L30 of the large (60S) ribosomal subunit, nearly identical to Rpl24Bp and has similarity to rat L24 ribosomal protein; not essential for translation but may be required for normal translation rate
YGL158W 27.65
RCK1
Protein kinase involved in the response to oxidative stress; identified as suppressor of S. pombe cell cycle checkpoint mutations
YEL029C 27.57
BUD16
Putative pyridoxal kinase, key enzyme in vitamin B6 metabolism; involved in maintaining levels of pyridoxal 5'-phosphate, the active form of vitamin B6; required for genome integrity; homolog of E. coli PdxK; involved in bud-site selection
YML026C 27.46
RPS18B
Protein component of the small (40S) ribosomal subunit; nearly identical to Rps18Ap and has similarity to E. coli S13 and rat S18 ribosomal proteins
YLR154C 27.28
RNH203
Ribonuclease H2 subunit, required for RNase H2 activity
YJL200C 27.07
ACO2
Putative mitochondrial aconitase isozyme; similarity to Aco1p, an aconitase required for the TCA cycle; expression induced during growth on glucose, by amino acid starvation via Gcn4p, and repressed on ethanol
YJL158C 26.84
CIS3
Mannose-containing glycoprotein constituent of the cell wall; member of the PIR (proteins with internal repeats) family
YCR016W 26.72 Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the nucleolus and nucleus; YCR016W is not an essential gene
YLR432W 26.10
IMD3
Inosine monophosphate dehydrogenase, catalyzes the first step of GMP biosynthesis, member of a four-gene family in S. cerevisiae, constitutively expressed
YNL248C 26.04
RPA49
RNA polymerase I subunit A49
YPR102C 25.94
RPL11A
Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl11Bp; involved in ribosomal assembly; depletion causes degradation of proteins and RNA of the 60S subunit; has similarity to E. coli L5 and rat L11
YKR043C 25.91 Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus
YNL302C 25.91
RPS19B
Protein component of the small (40S) ribosomal subunit, required for assembly and maturation of pre-40 S particles; mutations in human RPS19 are associated with Diamond Blackfan anemia; nearly identical to Rps19Ap
YDL081C 25.80
RPP1A
Ribosomal stalk protein P1 alpha, involved in the interaction between translational elongation factors and the ribosome; accumulation of P1 in the cytoplasm is regulated by phosphorylation and interaction with the P2 stalk component
YKL219W 25.76
COS9
Protein of unknown function, member of the DUP380 subfamily of conserved, often subtelomerically-encoded proteins
YPL211W 25.67
NIP7
Nucleolar protein required for 60S ribosome subunit biogenesis, constituent of 66S pre-ribosomal particles; physically interacts with Nop8p and the exosome subunit Rrp43p
YGR090W 25.26
UTP22
Possible U3 snoRNP protein involved in maturation of pre-18S rRNA, based on computational analysis of large-scale protein-protein interaction data
YPL227C 25.26
ALG5
UDP-glucose:dolichyl-phosphate glucosyltransferase, involved in asparagine-linked glycosylation in the endoplasmic reticulum
YDL205C 24.97
HEM3
Phorphobilinogen deaminase, catalyzes the conversion of 4-porphobilinogen to hydroxymethylbilane, the third step in the heme biosynthetic pathway; localizes to both the cytoplasm and nucleus; expression is regulated by Hap2p-Hap3p
YFL026W 24.57
STE2
Receptor for alpha-factor pheromone; seven transmembrane-domain GPCR that interacts with both pheromone and a heterotrimeric G protein to initiate the signaling response that leads to mating between haploid a and alpha cells
YIL016W 24.27
SNL1
Protein of unknown function proposed to be involved in nuclear pore complex biogenesis and maintenance as well as protein folding; has similarity to the mammalian BAG-1 protein
YLR129W 24.27
DIP2
Nucleolar protein, specifically associated with the U3 snoRNA, part of the large ribonucleoprotein complex known as the small subunit (SSU) processome, required for 18S rRNA biogenesis, part of the active pre-rRNA processing complex
YGL030W 24.25
RPL30
Protein component of the large (60S) ribosomal subunit, has similarity to rat L30 ribosomal protein; involved in pre-rRNA processing in the nucleolus; autoregulates splicing of its transcript
YKR026C 24.19
GCN3
Alpha subunit of the translation initiation factor eIF2B, the guanine-nucleotide exchange factor for eIF2; activity subsequently regulated by phosphorylated eIF2; first identified as a positive regulator of GCN4 expression
YOL121C 24.07
RPS19A
Protein component of the small (40S) ribosomal subunit, required for assembly and maturation of pre-40 S particles; mutations in human RPS19 are associated with Diamond Blackfan anemia; nearly identical to Rps19Bp
YLR180W 23.97
SAM1
S-adenosylmethionine synthetase, catalyzes transfer of the adenosyl group of ATP to the sulfur atom of methionine; one of two differentially regulated isozymes (Sam1p and Sam2p)
YMR290C 23.95
HAS1
ATP-dependent RNA helicase; localizes to both the nuclear periphery and nucleolus; highly enriched in nuclear pore complex fractions; constituent of 66S pre-ribosomal particles
YKR057W 23.83
RPS21A
Protein component of the small (40S) ribosomal subunit; nearly identical to Rps21Bp and has similarity to rat S21 ribosomal protein
YMR290W-A 23.76 Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data; overlaps 5' end of essential HAS1 gene which encodes an ATP-dependent RNA helicase
YAL007C 23.61
ERP2
Protein that forms a heterotrimeric complex with Erp1p, Emp24p, and Erv25p; member, along with Emp24p and Erv25p, of the p24 family involved in ER to Golgi transport and localized to COPII-coated vesicles
YNL016W 23.59
PUB1
Poly(A)+ RNA-binding protein, abundant mRNP-component protein that binds mRNA and is required for stability of a number of mRNAs; not reported to associate with polyribosomes
YDL085C-A 23.47 Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus
YMR309C 23.47
NIP1
Subunit of the eukaryotic translation initiation factor 3 (eIF3), involved in the assembly of preinitiation complex and start codon selection
YHR005C-A 23.30
MRS11
Essential protein of the mitochondrial intermembrane space, forms a complex with Tim9p (TIM10 complex) that mediates insertion of hydrophobic proteins at the inner membrane, has homology to Mrs5p, which is also involved in this process
YPL249C-A 23.28
RPL36B
Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl36Ap and has similarity to rat L36 ribosomal protein; binds to 5.8 S rRNA
YIL078W 23.16
THS1
Threonyl-tRNA synthetase, essential cytoplasmic protein
YPR010C 23.04
RPA135
RNA polymerase I subunit A135
YPR060C 22.84
ARO7
Chorismate mutase, catalyzes the conversion of chorismate to prephenate to initiate the tyrosine/phenylalanine-specific branch of aromatic amino acid biosynthesis
YHR094C 22.59
HXT1
Low-affinity glucose transporter of the major facilitator superfamily, expression is induced by Hxk2p in the presence of glucose and repressed by Rgt1p when glucose is limiting
YMR296C 22.59
LCB1
Component of serine palmitoyltransferase, responsible along with Lcb2p for the first committed step in sphingolipid synthesis, which is the condensation of serine with palmitoyl-CoA to form 3-ketosphinganine
YOR096W 22.44
RPS7A
Protein component of the small (40S) ribosomal subunit, nearly identical to Rps7Bp; interacts with Kti11p; deletion causes hypersensitivity to zymocin; has similarity to rat S7 and Xenopus S8 ribosomal proteins
YJR063W 22.33
RPA12
RNA polymerase I subunit A12.2; contains two zinc binding domains, and the N terminal domain is responsible for anchoring to the RNA pol I complex
YPR069C 22.32
SPE3
Spermidine synthase, involved in biosynthesis of spermidine and also in biosynthesis of pantothenic acid; spermidine is required for growth of wild-type cells
YNL010W 22.30 Putative protein of unknown function with similarity to phosphoserine phosphatases; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus; homozygous diploid mutant shows an increase in glycogen accumulation
YOR277C 22.28 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; almost completely overlaps the verified gene CAF20
YGL123C-A 22.24 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; overlaps the verified gene RPS2/YGL123W
YLR154W-B 22.19 Dubious open reading frame unlikely to encode a protein; encoded within the the 25S rRNA gene on the opposite strand
YLR154W-A 22.11 Dubious open reading frame unlikely to encode a protein; encoded within the the 25S rRNA gene on the opposite strand
YGL123W 22.07
RPS2
Protein component of the small (40S) subunit, essential for control of translational accuracy; has similarity to E. coli S5 and rat S2 ribosomal proteins
YDR095C 22.03 Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data
YGR123C 22.02
PPT1
Protein serine/threonine phosphatase with similarity to human phosphatase PP5; present in both the nucleus and cytoplasm; expressed during logarithmic growth; computational analyses suggest roles in phosphate metabolism and rRNA processing
YOR344C 21.98
TYE7
Serine-rich protein that contains a basic-helix-loop-helix (bHLH) DNA binding motif; binds E-boxes of glycolytic genes and contributes to their activation; may function as a transcriptional activator in Ty1-mediated gene expression
YPL142C 21.88 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; completely overlaps the verified ORF RPL33A/YPL143W, a component of the large (60S) ribosomal subunit
YDR146C 21.78
SWI5
Transcription factor that activates transcription of genes expressed at the M/G1 phase boundary and in G1 phase; localization to the nucleus occurs during G1 and appears to be regulated by phosphorylation by Cdc28p kinase
YBR238C 21.76 Mitochondrial membrane protein with similarity to Rmd9p; not required for respiratory growth but causes a synthetic respiratory defect in combination with rmd9 mutations; transcriptionally up-regulated by TOR; deletion increases life span
YKL182W 21.70
FAS1
Beta subunit of fatty acid synthetase, which catalyzes the synthesis of long-chain saturated fatty acids; contains acetyltransacylase, dehydratase, enoyl reductase, malonyl transacylase, and palmitoyl transacylase activities
YER007C-A 21.65
TMA20
Protein of unknown function that associates with ribosomes and has a putative RNA binding domain; interacts with Tma22p; null mutant exhibits translation defects; has homology to human oncogene MCT-1
YPL273W 21.65
SAM4
S-adenosylmethionine-homocysteine methyltransferase, functions along with Mht1p in the conversion of S-adenosylmethionine (AdoMet) to methionine to control the methionine/AdoMet ratio
YHR068W 21.60
DYS1
Deoxyhypusine synthase, catalyzes formation of deoxyhypusine, the first step in hypusine biosynthesis; triggers posttranslational hypusination of translation elongation factor eIF-5A and regulates its intracellular levels; tetrameric
YHR143W-A 21.52
RPC10
RNA polymerase subunit, found in RNA polymerase complexes I, II, and III
YBR191W 21.40
RPL21A
Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl21Bp and has similarity to rat L21 ribosomal protein
YHR196W 21.35
UTP9
Nucleolar protein, component of the small subunit (SSU) processome containing the U3 snoRNA that is involved in processing of pre-18S rRNA
YMR303C 21.15
ADH2
Glucose-repressible alcohol dehydrogenase II, catalyzes the conversion of ethanol to acetaldehyde; involved in the production of certain carboxylate esters; regulated by ADR1
YLR367W 20.97
RPS22B
Protein component of the small (40S) ribosomal subunit; nearly identical to Rps22Ap and has similarity to E. coli S8 and rat S15a ribosomal proteins
YDR094W 20.94 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps verified ORF DNF2
YLL045C 20.76
RPL8B
Ribosomal protein L4 of the large (60S) ribosomal subunit, nearly identical to Rpl8Ap and has similarity to rat L7a ribosomal protein; mutation results in decreased amounts of free 60S subunits
YML088W 20.53
UFO1
F-box receptor protein, subunit of the Skp1-Cdc53-F-box receptor (SCF) E3 ubiquitin ligase complex; binds to phosphorylated Ho endonuclease, allowing its ubiquitylation by SCF and subsequent degradation
YGR128C 20.53
UTP8
Nucleolar protein required for export of tRNAs from the nucleus; also copurifies with the small subunit (SSU) processome containing the U3 snoRNA that is involved in processing of pre-18S rRNA
YER052C 20.51
HOM3
Aspartate kinase (L-aspartate 4-P-transferase); cytoplasmic enzyme that catalyzes the first step in the common pathway for methionine and threonine biosynthesis; expression regulated by Gcn4p and the general control of amino acid synthesis
YPL243W 20.43
SRP68
Core component of the signal recognition particle (SRP) ribonucleoprotein (RNP) complex that functions in targeting nascent secretory proteins to the endoplasmic reticulum (ER) membrane
YEL054C 20.43
RPL12A
Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl12Bp; rpl12a rpl12b double mutant exhibits slow growth and slow translation; has similarity to E. coli L11 and rat L12 ribosomal proteins
YER056C-A 20.41
RPL34A
Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl34Bp and has similarity to rat L34 ribosomal protein
YBL039C 20.40
URA7
Major CTP synthase isozyme (see also URA8), catalyzes the ATP-dependent transfer of the amide nitrogen from glutamine to UTP, forming CTP, the final step in de novo biosynthesis of pyrimidines; involved in phospholipid biosynthesis
YDR091C 20.38
RLI1
Essential iron-sulfur protein required for ribosome biogenesis and translation initiation; facilitates binding of a multifactor complex (MFC) of translation initiation factors to the small ribosomal subunit; predicted ABC family ATPase
YCR018C 20.36
SRD1
Protein involved in the processing of pre-rRNA to mature rRNA; contains a C2/C2 zinc finger motif; srd1 mutation suppresses defects caused by the rrp1-1 mutation
YAL036C 20.28
RBG1
Member of the DRG family of GTP-binding proteins; interacts with translating ribosomes and with Tma46p
YML063W 20.27
RPS1B
Ribosomal protein 10 (rp10) of the small (40S) subunit; nearly identical to Rps1Ap and has similarity to rat S3a ribosomal protein
YJL198W 20.27
PHO90
Low-affinity phosphate transporter; deletion of pho84, pho87, pho89, pho90, and pho91 causes synthetic lethality; transcription independent of Pi and Pho4p activity; overexpression results in vigorous growth
YLR449W 19.91
FPR4
Peptidyl-prolyl cis-trans isomerase (PPIase) (proline isomerase) localized to the nucleus; catalyzes isomerization of proline residues in histones H3 and H4, which affects lysine methylation of those histones
YLL011W 19.73
SOF1
Essential protein required for biogenesis of 40S (small) ribosomal subunit; has similarity to the beta subunit of trimeric G-proteins and the splicing factor Prp4p
YJL177W 19.73
RPL17B
Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl17Ap and has similarity to E. coli L22 and rat L17 ribosomal proteins
YBR143C 19.60
SUP45
Polypeptide release factor involved in translation termination; mutant form acts as a recessive omnipotent suppressor
YNR054C 19.47
ESF2
Essential nucleolar protein involved in pre-18S rRNA processing; binds to RNA and stimulates ATPase activity of Dbp8; involved in assembly of the small subunit (SSU) processome
YPL245W 19.42 Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to both the nucleus and the cytoplasm
YDR344C 19.32 Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data
YAL003W 19.28
EFB1
Translation elongation factor 1 beta; stimulates nucleotide exchange to regenerate EF-1 alpha-GTP for the next elongation cycle; part of the EF-1 complex, which facilitates binding of aminoacyl-tRNA to the ribosomal A site
YKL056C 19.16
TMA19
Protein that associates with ribosomes; homolog of translationally controlled tumor protein; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and relocates to the mitochondrial outer surface upon oxidative stress
YCR072C 19.14
RSA4
WD-repeat protein involved in ribosome biogenesis; may interact with ribosomes; required for maturation and efficient intra-nuclear transport or pre-60S ribosomal subunits, localizes to the nucleolus
YHL039W 18.75 Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm
YDR060W 18.65
MAK21
Constituent of 66S pre-ribosomal particles, required for large (60S) ribosomal subunit biogenesis; involved in nuclear export of pre-ribosomes; required for maintenance of dsRNA virus; homolog of human CAATT-binding protein
YJR047C 18.63
ANB1
Translation initiation factor eIF-5A, promotes formation of the first peptide bond; similar to and functionally redundant with Hyp2p; undergoes an essential hypusination modification; expressed under anaerobic conditions
YML093W 18.63
UTP14
Nucleolar protein, component of the small subunit (SSU) processome containing the U3 snoRNA that is involved in processing of pre-18S rRNA
YHR089C 18.55
GAR1
Protein component of the H/ACA snoRNP pseudouridylase complex, involved in the modification and cleavage of the 18S pre-rRNA
YBR034C 18.54
HMT1
Nuclear SAM-dependent mono- and asymmetric arginine dimethylating methyltransferase that modifies hnRNPs, including Npl3p and Hrp1p, thus facilitating nuclear export of these proteins; required for viability of npl3 mutants
YGR124W 18.52
ASN2
Asparagine synthetase, isozyme of Asn1p; catalyzes the synthesis of L-asparagine from L-aspartate in the asparagine biosynthetic pathway
YER046W 18.51
SPO73
Meiosis-specific protein of unknown function, required for spore wall formation during sporulation; dispensible for both nuclear divisions during meiosis
YER026C 18.40
CHO1
Phosphatidylserine synthase, functions in phospholipid biosynthesis; catalyzes the reaction CDP-diaclyglycerol + L-serine = CMP + L-1-phosphatidylserine, transcriptionally repressed by myo-inositol and choline
YDR278C 18.25 Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data
YFL022C 18.23
FRS2
Alpha subunit of cytoplasmic phenylalanyl-tRNA synthetase, forms a tetramer with Frs1p to form active enzyme; evolutionarily distant from mitochondrial phenylalanyl-tRNA synthetase based on protein sequence, but substrate binding is similar
YPL079W 18.11
RPL21B
Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl21Ap and has similarity to rat L21 ribosomal protein
YLR075W 18.09
RPL10
Protein component of the large (60S) ribosomal subunit, responsible for joining the 40S and 60S subunits; regulates translation initiation; has similarity to rat L10 ribosomal protein and to members of the QM gene family
YEL026W 18.09
SNU13
RNA binding protein, part of U3 snoRNP involved in rRNA processing, part of U4/U6-U5 tri-snRNP involved in mRNA splicing, similar to human 15.5K protein
YGL242C 18.06 Putative protein of unknown function; deletion mutant is viable
YER131W 18.05
RPS26B
Protein component of the small (40S) ribosomal subunit; nearly identical to Rps26Ap and has similarity to rat S26 ribosomal protein
YHR066W 17.97
SSF1
Constituent of 66S pre-ribosomal particles, required for ribosomal large subunit maturation; functionally redundant with Ssf2p; member of the Brix family
YDL014W 17.96
NOP1
Nucleolar protein, component of the small subunit processome complex, which is required for processing of pre-18S rRNA; has similarity to mammalian fibrillarin
YNL141W 17.95
AAH1
Adenine deaminase (adenine aminohydrolase), converts adenine to hypoxanthine; involved in purine salvage; transcriptionally regulated by nutrient levels and growth phase; Aah1p degraded upon entry into quiescence via SCF and the proteasome
YDR450W 17.91
RPS18A
Protein component of the small (40S) ribosomal subunit; nearly identical to Rps18Bp and has similarity to E. coli S13 and rat S18 ribosomal proteins
YCR043C 17.89 Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the Golgi apparatus; YCR043C is not an essential gene
YGR151C 17.88 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; overlaps almost completely with the verified ORF RSR1/BUD1/YGR152C
YMR011W 17.77
HXT2
High-affinity glucose transporter of the major facilitator superfamily, expression is induced by low levels of glucose and repressed by high levels of glucose
YHR141C 17.63
RPL42B
Protein component of the large (60S) ribosomal subunit, identical to Rpl42Ap and has similarity to rat L44; required for propagation of the killer toxin-encoding M1 double-stranded RNA satellite of the L-A double-stranded RNA virus
YPL220W 17.62
RPL1A
N-terminally acetylated protein component of the large (60S) ribosomal subunit, nearly identical to Rpl1Bp and has similarity to E. coli L1 and rat L10a ribosomal proteins; rpl1a rpl1b double null mutation is lethal
YDL191W 17.60
RPL35A
Protein component of the large (60S) ribosomal subunit, identical to Rpl35Bp and has similarity to rat L35 ribosomal protein
YOR046C 17.54
DBP5
Cytoplasmic ATP-dependent RNA helicase of the DEAD-box family involved in mRNA export from the nucleus; involved in translation termination
YLR355C 17.53
ILV5
Acetohydroxyacid reductoisomerase, mitochondrial protein involved in branched-chain amino acid biosynthesis, also required for maintenance of wild-type mitochondrial DNA and found in mitochondrial nucleoids
YGL078C 17.53
DBP3
Putative ATP-dependent RNA helicase of the DEAD-box family involved in ribosomal biogenesis
YLR060W 17.53
FRS1
Beta subunit of cytoplasmic phenylalanyl-tRNA synthetase, forms a tetramer with Frs2p to generate active enzyme; sequence is evolutionarily distant from mitochondrial phenylalanyl-tRNA synthetase (Msf1p), but substrate binding is similar
YMR230W 17.46
RPS10B
Protein component of the small (40S) ribosomal subunit; nearly identical to Rps10Ap and has similarity to rat ribosomal protein S10
YCL036W 17.45
GFD2
Protein of unknown function, identified as a high-copy suppressor of a dbp5 mutation
YGL020C 17.45
GET1
Subunit of the GET complex; required for the retrieval of HDEL proteins from the Golgi to the ER in an ERD2 dependent fashion and for normal mitochondrial morphology and inheritance
YDR382W 17.41
RPP2B
Ribosomal protein P2 beta, a component of the ribosomal stalk, which is involved in the interaction between translational elongation factors and the ribosome; regulates the accumulation of P1 (Rpp1Ap and Rpp1Bp) in the cytoplasm
YBR084W 17.36
MIS1
Mitochondrial C1-tetrahydrofolate synthase, involved in interconversion between different oxidation states of tetrahydrofolate (THF); provides activities of formyl-THF synthetase, methenyl-THF cyclohydrolase, and methylene-THF dehydrogenase
YGL077C 17.35
HNM1
Choline/ethanolamine transporter; involved in the uptake of nitrogen mustard and the uptake of glycine betaine during hypersaline stress; co-regulated with phospholipid biosynthetic genes and negatively regulated by choline and myo-inositol
YPR157W 17.35 Putative protein of unknown function; induced by treatment with 8-methoxypsoralen and UVA irradiation
YDR045C 17.28
RPC11
RNA polymerase III subunit C11; mediates pol III RNA cleavage activity and is important for termination of transcription; homologous to TFIIS
YIL148W 17.26
RPL40A
Fusion protein, identical to Rpl40Bp, that is cleaved to yield ubiquitin and a ribosomal protein of the large (60S) ribosomal subunit with similarity to rat L40; ubiquitin may facilitate assembly of the ribosomal protein into ribosomes
YLR339C 17.24 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the essential gene RPP0
YDR101C 17.17
ARX1
Shuttling pre-60S factor; involved in the biogenesis of ribosomal large subunit biogenesis; interacts directly with Alb1; responsible for Tif6 recycling defects in absence of Rei1; associated with the ribosomal export complex
YLR409C 17.16
UTP21
Possible U3 snoRNP protein involved in maturation of pre-18S rRNA, based on computational analysis of large-scale protein-protein interaction data
YDR133C 17.16 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps YDR134C
YBR121C 17.14
GRS1
Cytoplasmic and mitochondrial glycyl-tRNA synthase that ligates glycine to the cognate anticodon bearing tRNA; transcription termination factor that may interact with the 3'-end of pre-mRNA to promote 3'-end formation
YER091C 17.13
MET6
Cobalamin-independent methionine synthase, involved in amino acid biosynthesis; requires a minimum of two glutamates on the methyltetrahydrofolate substrate, similar to bacterial metE homologs
YGR103W 17.12
NOP7
Nucleolar protein involved in rRNA processing and 60S ribosomal subunit biogenesis; constituent of several different pre-ribosomal particles; required for exit from G0 and the initiation of cell proliferation
YNL209W 17.07
SSB2
Cytoplasmic ATPase that is a ribosome-associated molecular chaperone, functions with J-protein partner Zuo1p; may be involved in the folding of newly-synthesized polypeptide chains; member of the HSP70 family; homolog of SSB1
YDR023W 16.99
SES1
Cytosolic seryl-tRNA synthetase, class II aminoacyl-tRNA synthetase that aminoacylates tRNA(Ser), displays tRNA-dependent amino acid recognition which enhances discrimination of the serine substrate, interacts with peroxin Pex21p
YDL134C 16.90
PPH21
Catalytic subunit of protein phosphatase 2A, functionally redundant with Pph22p; methylated at C terminus; forms alternate complexes with several regulatory subunits; involved in signal transduction and regulation of mitosis
YBR079C 16.85
RPG1
Subunit of the core complex of translation initiation factor 3(eIF3), essential for translation; part of a subcomplex (Prt1p-Rpg1p-Nip1p) that stimulates binding of mRNA and tRNA(i)Met to ribosomes
YOR340C 16.84
RPA43
RNA polymerase I subunit A43
YEL056W 16.83
HAT2
Subunit of the Hat1p-Hat2p histone acetyltransferase complex; required for high affinity binding of the complex to free histone H4, thereby enhancing Hat1p activity; similar to human RbAp46 and 48; has a role in telomeric silencing
YHR071C-A 16.80 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified ORF ERG7/YHR072W
YLL044W 16.77 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; transcription of both YLL044W and the overlapping gene RPL8B is reduced in the gcr1 null mutant
YNL112W 16.71
DBP2
Essential ATP-dependent RNA helicase of the DEAD-box protein family, involved in nonsense-mediated mRNA decay and rRNA processing
YER045C 16.64
ACA1
Basic leucine zipper (bZIP) transcription factor of the ATF/CREB family, may regulate transcription of genes involved in utilization of non-optimal carbon sources

Network of associatons between targets according to the STRING database.

First level regulatory network of STB3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
39.4 118.3 GO:0000098 sulfur amino acid catabolic process(GO:0000098)
28.1 140.7 GO:0006177 GMP biosynthetic process(GO:0006177)
18.6 55.9 GO:0009094 L-phenylalanine biosynthetic process(GO:0009094) erythrose 4-phosphate/phosphoenolpyruvate family amino acid biosynthetic process(GO:1902223)
17.6 87.8 GO:0000028 ribosomal small subunit assembly(GO:0000028)
16.4 49.3 GO:0046416 D-amino acid metabolic process(GO:0046416)
16.3 293.1 GO:0006407 rRNA export from nucleus(GO:0006407) rRNA transport(GO:0051029)
15.6 62.5 GO:0030497 fatty acid elongation(GO:0030497)
15.5 77.6 GO:0001676 long-chain fatty acid metabolic process(GO:0001676)
15.2 45.5 GO:0007189 adenylate cyclase-activating G-protein coupled receptor signaling pathway(GO:0007189)
14.2 42.7 GO:0008216 spermidine metabolic process(GO:0008216)
14.0 27.9 GO:0000461 endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000461)
13.2 39.5 GO:0070637 nicotinamide riboside metabolic process(GO:0046495) pyridine nucleoside metabolic process(GO:0070637)
13.1 52.3 GO:0046417 chorismate biosynthetic process(GO:0009423) chorismate metabolic process(GO:0046417)
12.8 51.3 GO:0031118 rRNA pseudouridine synthesis(GO:0031118)
12.7 38.2 GO:0002188 translation reinitiation(GO:0002188)
12.6 50.5 GO:0046500 S-adenosylmethionine metabolic process(GO:0046500)
12.0 36.1 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
12.0 84.1 GO:0010696 positive regulation of spindle pole body separation(GO:0010696)
11.6 34.8 GO:0031120 snRNA pseudouridine synthesis(GO:0031120) snRNA modification(GO:0040031)
11.6 381.6 GO:0000027 ribosomal large subunit assembly(GO:0000027)
11.1 33.2 GO:0018216 peptidyl-arginine modification(GO:0018195) peptidyl-arginine methylation(GO:0018216)
10.9 54.5 GO:0051083 'de novo' cotranslational protein folding(GO:0051083)
10.5 31.4 GO:0046083 adenine metabolic process(GO:0046083)
10.0 179.8 GO:0042797 tRNA transcription(GO:0009304) tRNA transcription from RNA polymerase III promoter(GO:0042797)
9.8 1211.6 GO:0002181 cytoplasmic translation(GO:0002181)
9.7 68.0 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
9.6 57.3 GO:0009088 threonine biosynthetic process(GO:0009088)
9.5 57.2 GO:0009099 valine biosynthetic process(GO:0009099)
9.4 37.7 GO:0006528 asparagine metabolic process(GO:0006528)
9.3 37.3 GO:0090502 RNA phosphodiester bond hydrolysis, endonucleolytic(GO:0090502)
8.6 223.8 GO:0000480 endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000480)
8.6 25.7 GO:0045901 positive regulation of translational elongation(GO:0045901)
8.4 302.7 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
8.0 31.8 GO:0042256 mature ribosome assembly(GO:0042256)
7.9 31.6 GO:0031057 negative regulation of histone modification(GO:0031057)
7.7 23.1 GO:1900544 positive regulation of nucleotide metabolic process(GO:0045981) positive regulation of purine nucleotide metabolic process(GO:1900544)
7.6 45.8 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
7.6 137.3 GO:0042790 transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:0042790)
7.5 7.5 GO:0046037 GMP metabolic process(GO:0046037)
7.3 29.2 GO:0034473 U1 snRNA 3'-end processing(GO:0034473)
7.1 21.3 GO:0009176 deoxyribonucleoside monophosphate biosynthetic process(GO:0009157) deoxyribonucleoside monophosphate metabolic process(GO:0009162) pyrimidine deoxyribonucleoside monophosphate metabolic process(GO:0009176) pyrimidine deoxyribonucleoside monophosphate biosynthetic process(GO:0009177)
7.1 14.2 GO:0071049 nuclear retention of pre-mRNA with aberrant 3'-ends at the site of transcription(GO:0071049)
7.0 84.0 GO:0006415 translational termination(GO:0006415)
6.9 41.5 GO:0006617 SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition(GO:0006617)
6.9 6.9 GO:0000491 small nucleolar ribonucleoprotein complex assembly(GO:0000491)
6.7 26.6 GO:0000296 spermine transport(GO:0000296)
6.5 19.6 GO:0015740 C4-dicarboxylate transport(GO:0015740)
6.1 110.1 GO:0030488 tRNA methylation(GO:0030488)
6.0 190.8 GO:0000054 ribosomal subunit export from nucleus(GO:0000054) ribosome localization(GO:0033750) establishment of ribosome localization(GO:0033753)
5.8 5.8 GO:0009394 pyrimidine deoxyribonucleotide metabolic process(GO:0009219) pyrimidine deoxyribonucleotide biosynthetic process(GO:0009221) 2'-deoxyribonucleotide biosynthetic process(GO:0009265) 2'-deoxyribonucleotide metabolic process(GO:0009394) deoxyribose phosphate biosynthetic process(GO:0046385)
5.6 28.0 GO:0042435 tryptophan biosynthetic process(GO:0000162) indole-containing compound biosynthetic process(GO:0042435) indolalkylamine biosynthetic process(GO:0046219)
5.5 16.6 GO:0009148 CTP biosynthetic process(GO:0006241) pyrimidine nucleoside triphosphate biosynthetic process(GO:0009148) pyrimidine ribonucleoside triphosphate metabolic process(GO:0009208) pyrimidine ribonucleoside triphosphate biosynthetic process(GO:0009209) CTP metabolic process(GO:0046036)
5.5 169.5 GO:0042273 ribosomal large subunit biogenesis(GO:0042273)
5.5 32.7 GO:0042274 ribosomal small subunit biogenesis(GO:0042274)
5.4 10.9 GO:0019348 polyprenol metabolic process(GO:0016093) polyprenol biosynthetic process(GO:0016094) dolichol metabolic process(GO:0019348) dolichol biosynthetic process(GO:0019408)
5.4 21.6 GO:0032262 pyrimidine ribonucleotide salvage(GO:0010138) pyrimidine nucleotide salvage(GO:0032262) pyrimidine nucleoside salvage(GO:0043097) UMP salvage(GO:0044206)
5.4 37.6 GO:0006782 protoporphyrinogen IX biosynthetic process(GO:0006782) protoporphyrinogen IX metabolic process(GO:0046501)
5.2 10.5 GO:0009186 deoxyribonucleoside diphosphate metabolic process(GO:0009186)
5.2 15.6 GO:0019401 glycerol biosynthetic process(GO:0006114) alditol biosynthetic process(GO:0019401)
5.2 15.6 GO:0035950 regulation of oligopeptide transport by regulation of transcription from RNA polymerase II promoter(GO:0035950) negative regulation of oligopeptide transport by negative regulation of transcription from RNA polymerase II promoter(GO:0035952) regulation of dipeptide transport by regulation of transcription from RNA polymerase II promoter(GO:0035953) negative regulation of dipeptide transport by negative regulation of transcription from RNA polymerase II promoter(GO:0035955) negative regulation of oligopeptide transport(GO:2000877) negative regulation of dipeptide transport(GO:2000879)
5.1 25.7 GO:0045338 terpenoid metabolic process(GO:0006721) terpenoid biosynthetic process(GO:0016114) farnesyl diphosphate biosynthetic process(GO:0045337) farnesyl diphosphate metabolic process(GO:0045338)
5.1 25.6 GO:0051351 positive regulation of ligase activity(GO:0051351)
5.1 20.4 GO:0031167 rRNA methylation(GO:0031167)
5.1 15.3 GO:0019673 GDP-mannose biosynthetic process(GO:0009298) GDP-mannose metabolic process(GO:0019673)
5.0 25.2 GO:0007535 donor selection(GO:0007535)
5.0 10.0 GO:0044209 AMP salvage(GO:0044209)
5.0 24.8 GO:1903530 regulation of exocytosis(GO:0017157) regulation of secretion(GO:0051046) regulation of secretion by cell(GO:1903530)
4.9 24.7 GO:0006032 aminoglycan catabolic process(GO:0006026) chitin catabolic process(GO:0006032) amino sugar catabolic process(GO:0046348) glucosamine-containing compound catabolic process(GO:1901072)
4.9 24.7 GO:0046655 folic acid metabolic process(GO:0046655) folic acid biosynthetic process(GO:0046656)
4.9 84.0 GO:0032508 DNA duplex unwinding(GO:0032508)
4.8 14.3 GO:0071482 cellular response to radiation(GO:0071478) cellular response to light stimulus(GO:0071482)
4.8 19.0 GO:0045048 protein insertion into ER membrane(GO:0045048)
4.7 32.6 GO:0000376 Group I intron splicing(GO:0000372) RNA splicing, via transesterification reactions with guanosine as nucleophile(GO:0000376)
4.6 69.7 GO:0006446 regulation of translational initiation(GO:0006446)
4.6 27.7 GO:0051260 protein homooligomerization(GO:0051260)
4.6 45.6 GO:0071047 nuclear polyadenylation-dependent mRNA catabolic process(GO:0071042) polyadenylation-dependent mRNA catabolic process(GO:0071047)
4.5 18.1 GO:0051597 response to methylmercury(GO:0051597) cellular response to methylmercury(GO:0071406)
4.5 13.5 GO:0031114 negative regulation of microtubule depolymerization(GO:0007026) regulation of microtubule depolymerization(GO:0031114)
4.5 31.2 GO:0006448 regulation of translational elongation(GO:0006448)
4.4 115.5 GO:0006413 translational initiation(GO:0006413)
4.4 26.2 GO:0006491 N-glycan processing(GO:0006491)
4.3 17.4 GO:0045896 regulation of transcription during mitosis(GO:0045896)
4.3 17.1 GO:0070070 proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
4.2 25.1 GO:0042823 pyridoxal phosphate metabolic process(GO:0042822) pyridoxal phosphate biosynthetic process(GO:0042823) aldehyde biosynthetic process(GO:0046184)
4.1 12.4 GO:0032006 regulation of TOR signaling(GO:0032006)
4.1 8.2 GO:0045128 negative regulation of reciprocal meiotic recombination(GO:0045128)
4.0 12.1 GO:0006068 ethanol catabolic process(GO:0006068) primary alcohol catabolic process(GO:0034310)
4.0 27.7 GO:0001522 pseudouridine synthesis(GO:0001522)
3.9 11.8 GO:0000154 rRNA modification(GO:0000154)
3.9 7.9 GO:0031684 heterotrimeric G-protein complex cycle(GO:0031684)
3.9 15.7 GO:0018279 peptidyl-asparagine modification(GO:0018196) protein N-linked glycosylation via asparagine(GO:0018279)
3.9 3.9 GO:0031590 wybutosine metabolic process(GO:0031590) wybutosine biosynthetic process(GO:0031591)
3.9 19.6 GO:0043555 regulation of translation in response to stress(GO:0043555)
3.9 3.9 GO:0006166 purine ribonucleoside salvage(GO:0006166)
3.9 7.8 GO:0016078 tRNA catabolic process(GO:0016078) nuclear polyadenylation-dependent tRNA catabolic process(GO:0071038)
3.9 19.3 GO:0034063 stress granule assembly(GO:0034063)
3.8 15.2 GO:0002943 tRNA dihydrouridine synthesis(GO:0002943)
3.7 102.4 GO:0006418 tRNA aminoacylation for protein translation(GO:0006418)
3.7 226.5 GO:0006364 rRNA processing(GO:0006364)
3.6 14.4 GO:0046341 CDP-diacylglycerol biosynthetic process(GO:0016024) CDP-diacylglycerol metabolic process(GO:0046341)
3.5 10.6 GO:0023021 termination of signal transduction(GO:0023021) termination of G-protein coupled receptor signaling pathway(GO:0038032)
3.5 3.5 GO:0006021 inositol biosynthetic process(GO:0006021)
3.5 14.0 GO:0051457 maintenance of protein location in nucleus(GO:0051457)
3.4 13.8 GO:0017182 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
3.4 13.5 GO:0050667 transsulfuration(GO:0019346) homocysteine metabolic process(GO:0050667)
3.4 13.5 GO:0090220 meiotic telomere clustering(GO:0045141) establishment of chromosome localization(GO:0051303) chromosome localization to nuclear envelope involved in homologous chromosome segregation(GO:0090220)
3.4 13.5 GO:0009113 purine nucleobase biosynthetic process(GO:0009113)
3.3 33.3 GO:0051231 mitotic spindle elongation(GO:0000022) spindle elongation(GO:0051231)
3.3 43.0 GO:0006999 nuclear pore organization(GO:0006999)
3.2 12.8 GO:0002143 tRNA wobble position uridine thiolation(GO:0002143)
3.1 43.6 GO:0001100 negative regulation of exit from mitosis(GO:0001100)
3.1 6.1 GO:0000416 positive regulation of histone H3-K36 methylation(GO:0000416) histone H3-K36 trimethylation(GO:0097198) regulation of histone H3-K36 trimethylation(GO:2001253) positive regulation of histone H3-K36 trimethylation(GO:2001255)
3.1 21.4 GO:0046513 ceramide metabolic process(GO:0006672) ceramide biosynthetic process(GO:0046513)
3.0 12.1 GO:0006110 regulation of glycolytic process(GO:0006110)
3.0 12.1 GO:0097549 heterochromatin organization involved in chromatin silencing(GO:0070868) chromatin organization involved in negative regulation of transcription(GO:0097549)
3.0 8.9 GO:0006654 phosphatidic acid biosynthetic process(GO:0006654) phosphatidic acid metabolic process(GO:0046473)
3.0 23.8 GO:0006814 sodium ion transport(GO:0006814)
3.0 23.7 GO:0006857 oligopeptide transport(GO:0006857)
2.9 29.5 GO:0007021 tubulin complex assembly(GO:0007021)
2.9 5.8 GO:0070525 tRNA threonylcarbamoyladenosine metabolic process(GO:0070525)
2.9 2.9 GO:0010695 regulation of spindle pole body separation(GO:0010695)
2.8 14.2 GO:0006564 L-serine biosynthetic process(GO:0006564)
2.8 11.3 GO:0060188 regulation of protein desumoylation(GO:0060188)
2.8 14.1 GO:0006551 leucine metabolic process(GO:0006551) leucine biosynthetic process(GO:0009098)
2.8 14.0 GO:0090158 regulation of phosphatidylinositol dephosphorylation(GO:0060304) endoplasmic reticulum membrane organization(GO:0090158)
2.7 13.6 GO:0015780 nucleotide-sugar transport(GO:0015780)
2.7 2.7 GO:0031398 positive regulation of protein ubiquitination(GO:0031398) positive regulation of protein modification by small protein conjugation or removal(GO:1903322)
2.7 5.4 GO:0000957 mitochondrial RNA catabolic process(GO:0000957)
2.7 8.0 GO:0032447 protein urmylation(GO:0032447)
2.7 29.3 GO:0015988 energy coupled proton transmembrane transport, against electrochemical gradient(GO:0015988) ATP hydrolysis coupled proton transport(GO:0015991) ATP hydrolysis coupled transmembrane transport(GO:0090662)
2.7 15.9 GO:0048478 replication fork protection(GO:0048478)
2.6 10.4 GO:0071326 cellular glucose homeostasis(GO:0001678) carbohydrate mediated signaling(GO:0009756) hexose mediated signaling(GO:0009757) sugar mediated signaling pathway(GO:0010182) glucose mediated signaling pathway(GO:0010255) carbohydrate homeostasis(GO:0033500) glucose homeostasis(GO:0042593) cellular response to monosaccharide stimulus(GO:0071326) cellular response to hexose stimulus(GO:0071331) cellular response to glucose stimulus(GO:0071333)
2.6 7.8 GO:0010922 positive regulation of phosphatase activity(GO:0010922) positive regulation of dephosphorylation(GO:0035306) positive regulation of protein dephosphorylation(GO:0035307)
2.6 13.0 GO:0046391 5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
2.5 5.0 GO:0030656 regulation of vitamin metabolic process(GO:0030656) positive regulation of vitamin metabolic process(GO:0046136) positive regulation of sulfur metabolic process(GO:0051176) regulation of thiamine biosynthetic process(GO:0070623) positive regulation of thiamine biosynthetic process(GO:0090180)
2.5 4.9 GO:0042992 negative regulation of transcription factor import into nucleus(GO:0042992)
2.5 17.3 GO:0055071 cellular manganese ion homeostasis(GO:0030026) manganese ion homeostasis(GO:0055071)
2.4 106.8 GO:0008033 tRNA processing(GO:0008033)
2.4 7.2 GO:0009451 RNA modification(GO:0009451)
2.4 21.2 GO:0006801 superoxide metabolic process(GO:0006801)
2.4 23.6 GO:0006272 leading strand elongation(GO:0006272)
2.3 21.1 GO:0042219 cellular modified amino acid catabolic process(GO:0042219)
2.3 9.3 GO:0001109 promoter clearance during DNA-templated transcription(GO:0001109) promoter clearance from RNA polymerase II promoter(GO:0001111)
2.3 20.8 GO:0031204 posttranslational protein targeting to membrane, translocation(GO:0031204)
2.3 6.9 GO:0033239 negative regulation of cellular amine metabolic process(GO:0033239)
2.3 9.2 GO:1901658 nucleoside catabolic process(GO:0009164) glycosyl compound catabolic process(GO:1901658)
2.3 9.0 GO:2000756 regulation of histone acetylation(GO:0035065) regulation of protein acetylation(GO:1901983) regulation of peptidyl-lysine acetylation(GO:2000756)
2.2 20.2 GO:0006474 N-terminal protein amino acid acetylation(GO:0006474)
2.2 20.2 GO:0000105 histidine biosynthetic process(GO:0000105) histidine metabolic process(GO:0006547) imidazole-containing compound metabolic process(GO:0052803)
2.2 4.5 GO:0009309 amine biosynthetic process(GO:0009309) cellular biogenic amine biosynthetic process(GO:0042401)
2.2 6.7 GO:1901879 regulation of protein depolymerization(GO:1901879) negative regulation of protein depolymerization(GO:1901880)
2.2 11.1 GO:0034315 regulation of Arp2/3 complex-mediated actin nucleation(GO:0034315) regulation of actin nucleation(GO:0051125)
2.2 13.2 GO:0000080 mitotic G1 phase(GO:0000080) G1 phase(GO:0051318)
2.2 8.7 GO:0044837 assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin structure organization(GO:0031032) actomyosin contractile ring organization(GO:0044837)
2.2 8.7 GO:0051131 chaperone-mediated protein complex assembly(GO:0051131)
2.1 8.5 GO:0031565 obsolete cytokinesis checkpoint(GO:0031565)
2.1 12.3 GO:0072337 modified amino acid transport(GO:0072337)
2.0 6.1 GO:1900436 filamentous growth of a population of unicellular organisms in response to starvation(GO:0036170) regulation of filamentous growth of a population of unicellular organisms in response to starvation(GO:1900434) positive regulation of filamentous growth of a population of unicellular organisms in response to starvation(GO:1900436)
2.0 8.1 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
2.0 16.2 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
2.0 2.0 GO:0031365 N-terminal protein amino acid modification(GO:0031365)
2.0 8.0 GO:0048209 regulation of COPII vesicle coating(GO:0003400) regulation of vesicle targeting, to, from or within Golgi(GO:0048209) regulation of ER to Golgi vesicle-mediated transport by GTP hydrolysis(GO:0090113)
2.0 12.0 GO:0006359 regulation of transcription from RNA polymerase III promoter(GO:0006359)
2.0 21.7 GO:0030011 maintenance of cell polarity(GO:0030011)
2.0 50.8 GO:0006487 protein N-linked glycosylation(GO:0006487)
1.9 21.3 GO:0007120 axial cellular bud site selection(GO:0007120)
1.9 7.7 GO:0055129 L-proline biosynthetic process(GO:0055129)
1.9 45.8 GO:0006696 ergosterol biosynthetic process(GO:0006696) phytosteroid biosynthetic process(GO:0016129) cellular alcohol biosynthetic process(GO:0044108) cellular lipid biosynthetic process(GO:0097384)
1.9 13.3 GO:0042991 transcription factor import into nucleus(GO:0042991)
1.9 9.5 GO:0016479 negative regulation of transcription from RNA polymerase I promoter(GO:0016479)
1.9 5.6 GO:0000042 protein targeting to Golgi(GO:0000042) establishment of protein localization to Golgi(GO:0072600)
1.9 93.7 GO:0016311 dephosphorylation(GO:0016311)
1.9 3.7 GO:0031384 regulation of initiation of mating projection growth(GO:0031384)
1.8 11.0 GO:0045292 mRNA cis splicing, via spliceosome(GO:0045292)
1.8 9.2 GO:0006694 steroid biosynthetic process(GO:0006694) sterol biosynthetic process(GO:0016126)
1.8 20.0 GO:0034221 cell wall chitin biosynthetic process(GO:0006038) fungal-type cell wall chitin biosynthetic process(GO:0034221) fungal-type cell wall polysaccharide biosynthetic process(GO:0051278) fungal-type cell wall polysaccharide metabolic process(GO:0071966)
1.8 19.9 GO:0072659 protein localization to plasma membrane(GO:0072659) establishment of protein localization to plasma membrane(GO:0090002) protein localization to cell periphery(GO:1990778)
1.8 14.3 GO:0007109 obsolete cytokinesis, completion of separation(GO:0007109)
1.8 12.5 GO:0009312 trehalose biosynthetic process(GO:0005992) oligosaccharide biosynthetic process(GO:0009312) disaccharide biosynthetic process(GO:0046351)
1.8 10.5 GO:0001402 signal transduction involved in filamentous growth(GO:0001402)
1.8 5.3 GO:1900101 regulation of endoplasmic reticulum unfolded protein response(GO:1900101)
1.7 3.5 GO:0051224 negative regulation of intracellular transport(GO:0032387) negative regulation of protein import into nucleus(GO:0042308) negative regulation of nucleocytoplasmic transport(GO:0046823) negative regulation of protein transport(GO:0051224) cellular response to biotic stimulus(GO:0071216) response to cell cycle checkpoint signaling(GO:0072396) response to mitotic cell cycle checkpoint signaling(GO:0072414) response to spindle checkpoint signaling(GO:0072417) response to mitotic spindle checkpoint signaling(GO:0072476) response to mitotic cell cycle spindle assembly checkpoint signaling(GO:0072479) response to spindle assembly checkpoint signaling(GO:0072485) negative regulation of intracellular protein transport(GO:0090317) negative regulation of protein localization to nucleus(GO:1900181) negative regulation of protein import into nucleus during spindle assembly checkpoint(GO:1901925) negative regulation of cytoplasmic transport(GO:1903650) negative regulation of cellular protein localization(GO:1903828) negative regulation of protein import(GO:1904590) negative regulation of establishment of protein localization(GO:1904950)
1.7 6.8 GO:0015883 FAD transport(GO:0015883)
1.7 13.5 GO:0055070 cellular copper ion homeostasis(GO:0006878) copper ion homeostasis(GO:0055070)
1.7 3.4 GO:0030847 termination of RNA polymerase II transcription, exosome-dependent(GO:0030847)
1.7 42.0 GO:0046939 nucleotide phosphorylation(GO:0046939)
1.7 3.3 GO:0071072 negative regulation of phospholipid biosynthetic process(GO:0071072) negative regulation of phospholipid metabolic process(GO:1903726)
1.7 6.7 GO:0046497 nicotinate nucleotide biosynthetic process(GO:0019357) nicotinate nucleotide salvage(GO:0019358) pyridine nucleotide salvage(GO:0019365) nicotinate nucleotide metabolic process(GO:0046497)
1.7 6.6 GO:0060277 obsolete negative regulation of transcription involved in G1 phase of mitotic cell cycle(GO:0060277)
1.6 3.3 GO:0031135 negative regulation of conjugation(GO:0031135) negative regulation of conjugation with cellular fusion(GO:0031138) negative regulation of multi-organism process(GO:0043901)
1.6 11.3 GO:1903338 regulation of cell wall organization or biogenesis(GO:1903338)
1.6 12.8 GO:0009395 phospholipid catabolic process(GO:0009395)
1.6 22.1 GO:0045047 protein targeting to ER(GO:0045047)
1.6 6.3 GO:0006344 maintenance of chromatin silencing(GO:0006344) maintenance of chromatin silencing at telomere(GO:0035392)
1.6 6.3 GO:0051601 exocyst localization(GO:0051601)
1.6 4.7 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
1.5 6.2 GO:0006056 cell wall mannoprotein biosynthetic process(GO:0000032) mannoprotein metabolic process(GO:0006056) mannoprotein biosynthetic process(GO:0006057) cell wall glycoprotein biosynthetic process(GO:0031506)
1.5 4.6 GO:0000916 actomyosin contractile ring contraction(GO:0000916) contractile ring contraction(GO:0036213)
1.5 16.5 GO:0034067 protein localization to Golgi apparatus(GO:0034067)
1.5 5.9 GO:0048313 Golgi inheritance(GO:0048313)
1.4 10.0 GO:0034729 histone H3-K79 methylation(GO:0034729)
1.4 4.3 GO:0033559 unsaturated fatty acid biosynthetic process(GO:0006636) unsaturated fatty acid metabolic process(GO:0033559)
1.4 4.3 GO:0045833 negative regulation of lipid metabolic process(GO:0045833)
1.4 1.4 GO:0061647 histone H3 acetylation(GO:0043966) histone H3-K9 acetylation(GO:0043970) histone H3-K14 acetylation(GO:0044154) histone H3-K9 modification(GO:0061647)
1.4 4.1 GO:1902808 positive regulation of G1/S transition of mitotic cell cycle(GO:1900087) positive regulation of cell cycle G1/S phase transition(GO:1902808)
1.4 8.2 GO:0016559 peroxisome fission(GO:0016559)
1.4 14.9 GO:0016973 poly(A)+ mRNA export from nucleus(GO:0016973)
1.4 2.7 GO:0051325 interphase(GO:0051325) mitotic interphase(GO:0051329)
1.4 2.7 GO:0034724 DNA replication-independent nucleosome organization(GO:0034724)
1.4 2.7 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
1.3 1.3 GO:0001174 DNA-templated transcriptional start site selection(GO:0001173) transcriptional start site selection at RNA polymerase II promoter(GO:0001174)
1.3 4.0 GO:0000388 spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)(GO:0000388)
1.3 1.3 GO:0009409 response to cold(GO:0009409) cellular response to cold(GO:0070417)
1.3 10.5 GO:0009636 response to toxic substance(GO:0009636)
1.3 13.0 GO:0016925 protein sumoylation(GO:0016925)
1.3 9.0 GO:0006797 polyphosphate metabolic process(GO:0006797)
1.3 11.4 GO:0045851 vacuolar acidification(GO:0007035) pH reduction(GO:0045851) intracellular pH reduction(GO:0051452)
1.3 2.5 GO:0071901 negative regulation of protein serine/threonine kinase activity(GO:0071901)
1.3 7.6 GO:0006771 riboflavin metabolic process(GO:0006771) riboflavin biosynthetic process(GO:0009231)
1.3 2.5 GO:0007030 Golgi organization(GO:0007030)
1.2 8.7 GO:0010526 negative regulation of transposition, RNA-mediated(GO:0010526) negative regulation of transposition(GO:0010529)
1.2 6.2 GO:0042439 ethanolamine-containing compound metabolic process(GO:0042439)
1.2 70.4 GO:0051302 regulation of cell division(GO:0051302)
1.2 9.7 GO:0042254 ribosome biogenesis(GO:0042254)
1.2 5.9 GO:0006469 negative regulation of protein kinase activity(GO:0006469)
1.2 2.3 GO:0033262 regulation of nuclear cell cycle DNA replication(GO:0033262)
1.2 11.5 GO:0031110 regulation of microtubule polymerization or depolymerization(GO:0031110)
1.2 6.9 GO:0006276 plasmid maintenance(GO:0006276)
1.1 8.0 GO:0044091 ascospore-type prospore membrane assembly(GO:0032120) membrane biogenesis(GO:0044091) membrane assembly(GO:0071709)
1.1 3.3 GO:0006688 glycosphingolipid biosynthetic process(GO:0006688)
1.1 4.4 GO:0036010 protein localization to endosome(GO:0036010)
1.1 31.2 GO:0006575 cellular modified amino acid metabolic process(GO:0006575)
1.1 2.1 GO:0008299 isoprenoid metabolic process(GO:0006720) isoprenoid biosynthetic process(GO:0008299)
1.1 3.2 GO:0006624 vacuolar protein processing(GO:0006624)
1.0 3.1 GO:0015809 arginine transport(GO:0015809)
1.0 1.0 GO:0034402 recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex(GO:0034402)
1.0 10.1 GO:0007076 mitotic chromosome condensation(GO:0007076)
1.0 2.0 GO:0046033 AMP biosynthetic process(GO:0006167) AMP metabolic process(GO:0046033)
1.0 15.0 GO:0006334 nucleosome assembly(GO:0006334)
1.0 7.8 GO:0009303 rRNA transcription(GO:0009303)
1.0 2.0 GO:0034389 lipid particle organization(GO:0034389)
1.0 1.0 GO:0070651 nonfunctional rRNA decay(GO:0070651)
1.0 4.8 GO:0006885 regulation of pH(GO:0006885)
1.0 4.8 GO:0044070 regulation of anion transport(GO:0044070)
0.9 3.7 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.9 9.2 GO:0008298 intracellular mRNA localization(GO:0008298)
0.9 10.1 GO:0006284 base-excision repair(GO:0006284)
0.9 4.5 GO:0051668 localization within membrane(GO:0051668)
0.9 6.3 GO:0007323 peptide pheromone maturation(GO:0007323)
0.9 3.6 GO:0006835 dicarboxylic acid transport(GO:0006835)
0.9 1.7 GO:0046777 protein autophosphorylation(GO:0046777)
0.9 1.7 GO:0007009 plasma membrane organization(GO:0007009)
0.9 6.0 GO:0009435 NAD biosynthetic process(GO:0009435)
0.9 3.4 GO:0006383 transcription from RNA polymerase III promoter(GO:0006383)
0.8 3.4 GO:0034755 iron ion transmembrane transport(GO:0034755)
0.8 1.7 GO:0006356 regulation of transcription from RNA polymerase I promoter(GO:0006356)
0.8 17.3 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.8 3.3 GO:0098742 agglutination involved in conjugation with cellular fusion(GO:0000752) agglutination involved in conjugation(GO:0000771) heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157) cell-cell adhesion(GO:0098609) adhesion between unicellular organisms(GO:0098610) multi organism cell adhesion(GO:0098740) cell-cell adhesion via plasma-membrane adhesion molecules(GO:0098742)
0.8 1.6 GO:0006037 cell wall chitin metabolic process(GO:0006037) cell wall polysaccharide metabolic process(GO:0010383)
0.8 2.4 GO:0006898 receptor-mediated endocytosis(GO:0006898)
0.8 2.4 GO:0009607 response to biotic stimulus(GO:0009607)
0.8 2.4 GO:0019419 sulfate assimilation, phosphoadenylyl sulfate reduction by phosphoadenylyl-sulfate reductase (thioredoxin)(GO:0019379) sulfate reduction(GO:0019419)
0.8 0.8 GO:0043065 positive regulation of cell death(GO:0010942) positive regulation of apoptotic process(GO:0043065) positive regulation of programmed cell death(GO:0043068)
0.8 3.1 GO:0009262 deoxyribonucleotide metabolic process(GO:0009262) deoxyribonucleotide biosynthetic process(GO:0009263)
0.8 2.3 GO:0070481 nuclear-transcribed mRNA catabolic process, non-stop decay(GO:0070481)
0.8 2.3 GO:0015886 heme transport(GO:0015886)
0.7 1.5 GO:0006545 glycine biosynthetic process(GO:0006545)
0.7 2.2 GO:0006264 mitochondrial DNA replication(GO:0006264)
0.7 9.4 GO:0006414 translational elongation(GO:0006414)
0.7 1.4 GO:0015909 long-chain fatty acid transport(GO:0015909)
0.7 2.1 GO:0009371 positive regulation of transcription from RNA polymerase II promoter by pheromones(GO:0007329) positive regulation of transcription by pheromones(GO:0009371)
0.7 9.6 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.7 2.7 GO:0045732 positive regulation of protein catabolic process(GO:0045732)
0.7 5.2 GO:0006283 transcription-coupled nucleotide-excision repair(GO:0006283)
0.6 5.2 GO:0051666 actin cortical patch localization(GO:0051666)
0.6 4.5 GO:0006882 cellular zinc ion homeostasis(GO:0006882) zinc ion homeostasis(GO:0055069)
0.6 2.6 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.6 2.5 GO:0031086 nuclear-transcribed mRNA catabolic process, deadenylation-independent decay(GO:0031086) deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.6 3.1 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.6 1.2 GO:0031532 actin cytoskeleton reorganization(GO:0031532) lipid tube assembly(GO:0060988) protein-lipid complex assembly(GO:0065005) protein-lipid complex subunit organization(GO:0071825)
0.6 29.6 GO:0006888 ER to Golgi vesicle-mediated transport(GO:0006888)
0.6 1.8 GO:0032042 mitochondrial DNA metabolic process(GO:0032042)
0.6 1.7 GO:0007234 osmosensory signaling via phosphorelay pathway(GO:0007234)
0.6 14.5 GO:0032259 methylation(GO:0032259)
0.6 0.6 GO:0016075 rRNA catabolic process(GO:0016075) ncRNA catabolic process(GO:0034661)
0.5 2.7 GO:1901136 carbohydrate derivative catabolic process(GO:1901136)
0.5 2.7 GO:0006611 protein export from nucleus(GO:0006611)
0.5 0.5 GO:0006399 tRNA metabolic process(GO:0006399)
0.5 6.2 GO:0030148 sphingolipid biosynthetic process(GO:0030148)
0.5 7.0 GO:0001300 chronological cell aging(GO:0001300)
0.5 6.6 GO:0031163 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.5 4.6 GO:0007121 bipolar cellular bud site selection(GO:0007121)
0.5 6.9 GO:0071900 regulation of protein serine/threonine kinase activity(GO:0071900)
0.4 4.5 GO:0006862 nucleotide transport(GO:0006862)
0.4 1.8 GO:0009306 protein secretion(GO:0009306)
0.4 2.2 GO:0006273 lagging strand elongation(GO:0006273)
0.4 9.2 GO:0006333 chromatin assembly or disassembly(GO:0006333)
0.4 9.5 GO:0042147 retrograde transport, endosome to Golgi(GO:0042147)
0.4 2.8 GO:0006267 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
0.4 2.3 GO:0070096 mitochondrial outer membrane translocase complex assembly(GO:0070096)
0.3 5.2 GO:0006633 fatty acid biosynthetic process(GO:0006633)
0.3 2.4 GO:0070816 phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.3 3.1 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.3 3.4 GO:0044744 protein targeting to nucleus(GO:0044744)
0.3 1.9 GO:0043457 regulation of cellular respiration(GO:0043457)
0.3 3.4 GO:0006098 pentose-phosphate shunt(GO:0006098) glyceraldehyde-3-phosphate metabolic process(GO:0019682) glucose 6-phosphate metabolic process(GO:0051156)
0.3 1.5 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.3 0.6 GO:0016320 endoplasmic reticulum membrane fusion(GO:0016320)
0.3 0.6 GO:0008105 asymmetric protein localization(GO:0008105)
0.3 0.6 GO:0009847 spore germination(GO:0009847)
0.3 0.5 GO:0006086 acetyl-CoA biosynthetic process from pyruvate(GO:0006086)
0.3 2.0 GO:0030472 mitotic spindle organization in nucleus(GO:0030472)
0.3 1.5 GO:0048017 inositol lipid-mediated signaling(GO:0048017)
0.2 14.8 GO:0006457 protein folding(GO:0006457)
0.2 1.7 GO:0046685 response to arsenic-containing substance(GO:0046685)
0.2 1.2 GO:0035434 copper ion transmembrane transport(GO:0035434)
0.2 0.9 GO:0000011 vacuole inheritance(GO:0000011)
0.2 0.6 GO:0072530 cytosine transport(GO:0015856) purine-containing compound transmembrane transport(GO:0072530)
0.2 1.3 GO:0006493 protein O-linked glycosylation(GO:0006493)
0.2 1.3 GO:0006744 ubiquinone metabolic process(GO:0006743) ubiquinone biosynthetic process(GO:0006744) ketone biosynthetic process(GO:0042181) quinone metabolic process(GO:1901661) quinone biosynthetic process(GO:1901663)
0.2 0.4 GO:0018342 protein prenylation(GO:0018342) prenylation(GO:0097354)
0.2 1.3 GO:0042138 meiotic DNA double-strand break formation(GO:0042138)
0.2 0.9 GO:0035493 SNARE complex assembly(GO:0035493) regulation of SNARE complex assembly(GO:0035542)
0.2 1.8 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.2 0.7 GO:0043007 maintenance of rDNA(GO:0043007)
0.2 1.5 GO:0006826 iron ion transport(GO:0006826)
0.2 0.2 GO:0006531 aspartate metabolic process(GO:0006531)
0.1 0.6 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.1 1.6 GO:0007097 nuclear migration(GO:0007097) establishment of nucleus localization(GO:0040023) nucleus localization(GO:0051647)
0.1 0.7 GO:0032273 positive regulation of protein polymerization(GO:0032273)
0.1 1.1 GO:0006526 arginine biosynthetic process(GO:0006526)
0.1 0.3 GO:0006089 lactate metabolic process(GO:0006089)
0.1 1.9 GO:0051169 nuclear transport(GO:0051169)
0.1 1.5 GO:0007015 actin filament organization(GO:0007015)
0.1 0.3 GO:0030261 chromosome condensation(GO:0030261)
0.1 0.1 GO:0006784 heme a biosynthetic process(GO:0006784) heme a metabolic process(GO:0046160)
0.1 0.1 GO:0042727 flavin-containing compound metabolic process(GO:0042726) flavin-containing compound biosynthetic process(GO:0042727)
0.1 0.3 GO:0046040 IMP biosynthetic process(GO:0006188) IMP metabolic process(GO:0046040)
0.1 0.1 GO:0030846 termination of RNA polymerase II transcription, poly(A)-coupled(GO:0030846)
0.0 0.3 GO:0006734 NADH metabolic process(GO:0006734)
0.0 0.1 GO:0051037 regulation of transcription from RNA polymerase II promoter involved in meiotic cell cycle(GO:0010672) negative regulation of transcription from RNA polymerase II promoter involved in meiotic cell cycle(GO:0010674) regulation of transcription involved in meiotic cell cycle(GO:0051037)
0.0 0.3 GO:0045324 late endosome to vacuole transport(GO:0045324)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
23.0 68.9 GO:0070545 PeBoW complex(GO:0070545)
18.4 55.3 GO:0032299 ribonuclease H2 complex(GO:0032299)
18.4 73.6 GO:0031428 box C/D snoRNP complex(GO:0031428)
15.8 110.7 GO:0005697 telomerase holoenzyme complex(GO:0005697)
13.7 191.4 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
13.5 1131.2 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
12.0 71.8 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
11.9 35.7 GO:0017102 methionyl glutamyl tRNA synthetase complex(GO:0017102)
11.3 56.7 GO:0030689 Noc complex(GO:0030689)
10.7 74.6 GO:0034455 t-UTP complex(GO:0034455)
10.6 106.1 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
10.2 30.7 GO:0097344 Rix1 complex(GO:0097344)
10.2 71.5 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
10.0 39.8 GO:0030287 cell wall-bounded periplasmic space(GO:0030287)
9.9 49.6 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)
9.5 581.5 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
9.5 161.7 GO:0032040 small-subunit processome(GO:0032040)
9.5 38.0 GO:0042788 polysomal ribosome(GO:0042788)
9.4 28.1 GO:0005854 nascent polypeptide-associated complex(GO:0005854)
9.1 9.1 GO:0034518 RNA cap binding complex(GO:0034518)
8.3 16.7 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
7.7 23.2 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
6.9 20.8 GO:0005845 mRNA cap binding complex(GO:0005845)
6.9 41.5 GO:0048500 signal recognition particle, endoplasmic reticulum targeting(GO:0005786) signal recognition particle(GO:0048500)
6.8 190.6 GO:0030686 90S preribosome(GO:0030686)
6.8 115.6 GO:0022626 cytosolic ribosome(GO:0022626)
6.4 264.1 GO:0030684 preribosome(GO:0030684)
6.4 38.2 GO:0043527 tRNA methyltransferase complex(GO:0043527)
6.3 19.0 GO:0043529 GET complex(GO:0043529)
5.8 34.8 GO:0035339 serine C-palmitoyltransferase complex(GO:0017059) SPOTS complex(GO:0035339)
5.7 17.0 GO:0071261 Ssh1 translocon complex(GO:0071261)
5.6 144.5 GO:0005844 polysome(GO:0005844)
5.4 37.5 GO:0000221 vacuolar proton-transporting V-type ATPase, V1 domain(GO:0000221) proton-transporting V-type ATPase, V1 domain(GO:0033180)
5.3 26.4 GO:0000408 EKC/KEOPS complex(GO:0000408)
5.1 25.6 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
4.6 64.4 GO:0010494 cytoplasmic stress granule(GO:0010494)
4.5 36.2 GO:0051233 spindle midzone(GO:0051233)
4.4 22.1 GO:0044462 cell wall part(GO:0044426) external encapsulating structure part(GO:0044462)
4.3 543.1 GO:0005730 nucleolus(GO:0005730)
4.3 21.6 GO:0005663 DNA replication factor C complex(GO:0005663)
3.9 19.7 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
3.9 15.6 GO:0097255 R2TP complex(GO:0097255)
3.8 11.5 GO:0016363 nuclear matrix(GO:0016363)
3.7 63.1 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
3.7 22.2 GO:0000136 alpha-1,6-mannosyltransferase complex(GO:0000136)
3.6 10.9 GO:0032301 MutSalpha complex(GO:0032301)
3.5 7.0 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
3.5 24.3 GO:0005884 actin filament(GO:0005884)
3.4 13.6 GO:0005971 ribonucleoside-diphosphate reductase complex(GO:0005971)
3.3 13.2 GO:0017053 transcriptional repressor complex(GO:0017053)
3.3 13.2 GO:0033597 mitotic checkpoint complex(GO:0033597)
3.1 9.3 GO:0005674 transcription factor TFIIF complex(GO:0005674)
3.1 9.2 GO:0070762 nuclear pore transmembrane ring(GO:0070762)
3.0 27.2 GO:0005832 chaperonin-containing T-complex(GO:0005832)
3.0 9.0 GO:0043625 delta DNA polymerase complex(GO:0043625)
3.0 11.9 GO:0031207 endoplasmic reticulum Sec complex(GO:0031205) Sec62/Sec63 complex(GO:0031207)
2.8 8.3 GO:0005796 Golgi lumen(GO:0005796)
2.7 11.0 GO:0005791 rough endoplasmic reticulum(GO:0005791) rough endoplasmic reticulum membrane(GO:0030867)
2.7 8.0 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
2.5 12.7 GO:0034044 exomer complex(GO:0034044)
2.5 2.5 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
2.5 15.2 GO:0033588 Elongator holoenzyme complex(GO:0033588)
2.5 10.2 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
2.5 53.1 GO:0005840 ribosome(GO:0005840)
2.5 10.0 GO:0044611 nuclear pore inner ring(GO:0044611)
2.5 59.1 GO:0031298 replication fork protection complex(GO:0031298)
2.3 15.8 GO:0000792 heterochromatin(GO:0000792)
2.2 13.3 GO:0032126 eisosome(GO:0032126)
2.2 17.3 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
2.2 6.5 GO:0031417 NatC complex(GO:0031417)
2.1 12.8 GO:0031080 nuclear pore outer ring(GO:0031080)
2.1 8.3 GO:0005946 alpha,alpha-trehalose-phosphate synthase complex (UDP-forming)(GO:0005946)
2.1 10.3 GO:0016272 prefoldin complex(GO:0016272)
2.0 16.4 GO:0030126 COPI vesicle coat(GO:0030126)
2.0 9.9 GO:0005880 nuclear microtubule(GO:0005880)
2.0 5.9 GO:0005787 signal peptidase complex(GO:0005787)
1.9 7.8 GO:0000445 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445) nucleoplasmic THO complex(GO:0000446)
1.9 11.5 GO:0072686 mitotic spindle(GO:0072686)
1.9 7.6 GO:0030892 mitotic cohesin complex(GO:0030892) nuclear mitotic cohesin complex(GO:0034990)
1.9 5.7 GO:0000346 transcription export complex(GO:0000346)
1.9 7.5 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
1.9 67.5 GO:0030134 ER to Golgi transport vesicle(GO:0030134)
1.8 7.2 GO:0005641 nuclear envelope lumen(GO:0005641)
1.8 65.8 GO:0005811 lipid particle(GO:0005811)
1.7 41.1 GO:0005887 integral component of plasma membrane(GO:0005887)
1.7 22.2 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
1.7 25.0 GO:0005940 septin ring(GO:0005940)
1.7 5.0 GO:0000930 gamma-tubulin small complex, spindle pole body(GO:0000928) gamma-tubulin complex(GO:0000930) gamma-tubulin small complex(GO:0008275)
1.7 11.6 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
1.7 8.3 GO:0016459 myosin complex(GO:0016459)
1.7 1.7 GO:0071561 nucleus-vacuole junction(GO:0071561)
1.6 9.9 GO:0044615 nuclear pore nuclear basket(GO:0044615)
1.5 4.6 GO:0000137 Golgi cis cisterna(GO:0000137)
1.5 7.6 GO:0030478 actin cap(GO:0030478)
1.4 5.7 GO:0031502 dolichyl-phosphate-mannose-protein mannosyltransferase complex(GO:0031502)
1.4 12.2 GO:0030137 COPI-coated vesicle(GO:0030137)
1.3 6.6 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
1.3 1.3 GO:0030428 cell septum(GO:0030428)
1.3 21.5 GO:0016586 RSC complex(GO:0016586)
1.2 7.2 GO:0035327 transcriptionally active chromatin(GO:0035327)
1.2 5.9 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
1.2 4.7 GO:0042597 periplasmic space(GO:0042597)
1.2 3.5 GO:0030894 DNA replication factor A complex(GO:0005662) replisome(GO:0030894) nuclear replisome(GO:0043601)
1.1 20.7 GO:0005685 U1 snRNP(GO:0005685)
1.1 4.6 GO:0001401 mitochondrial sorting and assembly machinery complex(GO:0001401)
1.1 7.9 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
1.1 6.7 GO:0070772 PAS complex(GO:0070772)
1.1 4.5 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
1.1 5.4 GO:0044614 nuclear pore cytoplasmic filaments(GO:0044614)
1.1 1.1 GO:0005688 U6 snRNP(GO:0005688)
1.1 4.3 GO:0033176 vacuolar proton-transporting V-type ATPase complex(GO:0016471) proton-transporting V-type ATPase complex(GO:0033176)
1.0 4.0 GO:0030907 MBF transcription complex(GO:0030907)
1.0 2.9 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.9 14.1 GO:0046695 SLIK (SAGA-like) complex(GO:0046695)
0.9 1.9 GO:0000131 incipient cellular bud site(GO:0000131)
0.9 13.6 GO:0030133 transport vesicle(GO:0030133)
0.9 8.1 GO:0005826 actomyosin contractile ring(GO:0005826) contractile ring(GO:0070938)
0.9 181.3 GO:0005829 cytosol(GO:0005829)
0.9 27.0 GO:0005643 nuclear pore(GO:0005643)
0.8 3.3 GO:0005797 Golgi medial cisterna(GO:0005797)
0.8 2.5 GO:0000814 ESCRT II complex(GO:0000814)
0.8 1.6 GO:0031414 N-terminal protein acetyltransferase complex(GO:0031414)
0.8 2.4 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.8 3.2 GO:0030123 AP-3 adaptor complex(GO:0030123)
0.8 7.9 GO:0030118 clathrin coat(GO:0030118)
0.7 9.7 GO:0098857 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.7 31.7 GO:0031227 intrinsic component of endoplasmic reticulum membrane(GO:0031227)
0.7 1.4 GO:0030008 TRAPP complex(GO:0030008)
0.7 3.5 GO:0005871 kinesin complex(GO:0005871)
0.7 2.7 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.6 86.4 GO:0005933 cellular bud(GO:0005933)
0.6 2.5 GO:0033254 vacuolar transporter chaperone complex(GO:0033254)
0.6 2.4 GO:0055087 Ski complex(GO:0055087)
0.5 128.1 GO:0005783 endoplasmic reticulum(GO:0005783)
0.5 1.4 GO:0030896 checkpoint clamp complex(GO:0030896)
0.5 1.9 GO:0030906 retromer, cargo-selective complex(GO:0030906)
0.5 1.4 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.5 1.4 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.5 25.4 GO:0000139 Golgi membrane(GO:0000139)
0.4 1.3 GO:0070985 TFIIK complex(GO:0070985)
0.4 2.9 GO:0000439 core TFIIH complex(GO:0000439) holo TFIIH complex(GO:0005675)
0.4 16.6 GO:0005794 Golgi apparatus(GO:0005794)
0.4 71.5 GO:0005759 mitochondrial matrix(GO:0005759)
0.4 3.2 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.4 0.7 GO:0030014 CCR4-NOT complex(GO:0030014)
0.3 2.7 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.3 0.3 GO:0030904 retromer complex(GO:0030904)
0.3 0.3 GO:0005801 cis-Golgi network(GO:0005801)
0.3 0.3 GO:0000145 exocyst(GO:0000145)
0.3 0.8 GO:0033186 CAF-1 complex(GO:0033186)
0.2 0.5 GO:0000798 nuclear cohesin complex(GO:0000798) cohesin complex(GO:0008278)
0.2 2.1 GO:0005838 proteasome regulatory particle(GO:0005838) proteasome accessory complex(GO:0022624)
0.2 0.6 GO:0000417 HIR complex(GO:0000417)
0.2 0.6 GO:0070823 HDA1 complex(GO:0070823)
0.2 1.7 GO:0036452 ESCRT complex(GO:0036452)
0.2 5.5 GO:0005874 microtubule(GO:0005874)
0.2 0.5 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.1 0.1 GO:0070209 ASTRA complex(GO:0070209)
0.1 0.6 GO:0070775 NuA3 histone acetyltransferase complex(GO:0033100) H3 histone acetyltransferase complex(GO:0070775)
0.1 1.3 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.1 0.4 GO:0033263 CORVET complex(GO:0033263)
0.1 0.7 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.1 0.7 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.1 0.1 GO:0031391 Elg1 RFC-like complex(GO:0031391)
0.1 0.2 GO:0042575 DNA polymerase complex(GO:0042575)
0.1 0.2 GO:0000796 condensin complex(GO:0000796) nuclear condensin complex(GO:0000799)
0.0 0.1 GO:0036387 nuclear pre-replicative complex(GO:0005656) pre-replicative complex(GO:0036387)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
35.0 105.1 GO:0003938 IMP dehydrogenase activity(GO:0003938)
20.8 62.5 GO:0009922 fatty acid elongase activity(GO:0009922)
19.7 118.1 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
17.2 51.6 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
14.1 56.5 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
13.7 191.4 GO:0001054 RNA polymerase I activity(GO:0001054)
12.0 36.1 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
11.1 33.2 GO:0016273 arginine N-methyltransferase activity(GO:0016273) protein-arginine N-methyltransferase activity(GO:0016274)
11.0 33.0 GO:0019202 amino acid kinase activity(GO:0019202)
10.6 106.1 GO:0001056 RNA polymerase III activity(GO:0001056)
9.8 9.8 GO:0032296 ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296)
9.8 195.6 GO:0030515 snoRNA binding(GO:0030515)
9.2 36.6 GO:0008172 S-methyltransferase activity(GO:0008172)
9.0 45.1 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
8.7 52.4 GO:0003993 acid phosphatase activity(GO:0003993)
8.5 50.8 GO:0003725 double-stranded RNA binding(GO:0003725)
8.5 84.5 GO:0009982 pseudouridine synthase activity(GO:0009982)
7.8 46.9 GO:0016408 C-acyltransferase activity(GO:0016408)
7.7 1604.5 GO:0003735 structural constituent of ribosome(GO:0003735)
7.5 30.0 GO:0016634 oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor(GO:0016634)
7.5 22.4 GO:0004930 G-protein coupled receptor activity(GO:0004930)
7.5 14.9 GO:0004467 long-chain fatty acid-CoA ligase activity(GO:0004467) fatty acid ligase activity(GO:0015645)
6.9 34.7 GO:0080130 L-phenylalanine aminotransferase activity(GO:0070546) L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
6.7 26.6 GO:0000297 spermine transmembrane transporter activity(GO:0000297)
6.6 26.4 GO:0019206 nucleoside kinase activity(GO:0019206)
6.5 19.5 GO:0016838 carbon-oxygen lyase activity, acting on phosphates(GO:0016838)
6.4 96.3 GO:0019843 rRNA binding(GO:0019843)
6.4 19.2 GO:0016882 cyclo-ligase activity(GO:0016882)
6.3 202.6 GO:0003743 translation initiation factor activity(GO:0003743)
6.3 18.9 GO:0004488 methylenetetrahydrofolate dehydrogenase (NADP+) activity(GO:0004488)
6.1 24.4 GO:0005527 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
6.0 24.0 GO:0003747 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
6.0 18.0 GO:0016300 tRNA (uracil) methyltransferase activity(GO:0016300)
5.8 46.0 GO:0016423 tRNA (guanine) methyltransferase activity(GO:0016423)
5.8 23.0 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
5.4 16.2 GO:0051010 microtubule plus-end binding(GO:0051010)
5.3 21.4 GO:0015146 pentose transmembrane transporter activity(GO:0015146)
5.3 10.6 GO:0043023 ribosomal large subunit binding(GO:0043023)
5.3 57.9 GO:0003727 single-stranded RNA binding(GO:0003727)
5.2 186.9 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765)
5.1 15.3 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
5.0 15.0 GO:0008242 omega peptidase activity(GO:0008242)
4.9 54.4 GO:0000049 tRNA binding(GO:0000049)
4.9 19.6 GO:0015556 C4-dicarboxylate transmembrane transporter activity(GO:0015556)
4.8 14.5 GO:0000339 RNA cap binding(GO:0000339)
4.8 157.9 GO:0003724 RNA helicase activity(GO:0003724)
4.8 9.5 GO:0031370 eukaryotic initiation factor 4G binding(GO:0031370)
4.7 18.8 GO:0005384 manganese ion transmembrane transporter activity(GO:0005384)
4.6 55.1 GO:0016866 intramolecular transferase activity(GO:0016866)
4.5 13.6 GO:0005262 calcium channel activity(GO:0005262)
4.5 18.1 GO:0016886 ligase activity, forming phosphoric ester bonds(GO:0016886)
4.4 26.7 GO:0070300 phosphatidic acid binding(GO:0070300)
4.4 137.8 GO:0016876 aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)
4.4 13.2 GO:0004691 cyclic nucleotide-dependent protein kinase activity(GO:0004690) cAMP-dependent protein kinase activity(GO:0004691)
4.4 74.8 GO:0016763 transferase activity, transferring pentosyl groups(GO:0016763)
4.4 26.3 GO:0016840 carbon-nitrogen lyase activity(GO:0016840)
4.4 17.4 GO:0043141 5'-3' DNA helicase activity(GO:0043139) ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
4.3 13.0 GO:0001169 transcription factor activity, RNA polymerase I CORE element sequence-specific binding(GO:0001169) transcription factor activity, RNA polymerase I CORE element binding transcription factor recruiting(GO:0001187)
4.3 12.8 GO:0043812 phosphatidylinositol phosphate 4-phosphatase activity(GO:0034596) phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812)
4.3 29.9 GO:0005216 ion channel activity(GO:0005216)
4.3 12.8 GO:0016433 rRNA (adenine) methyltransferase activity(GO:0016433)
4.2 21.1 GO:0008312 7S RNA binding(GO:0008312)
4.1 24.8 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
4.1 105.4 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
4.0 16.1 GO:0004622 lysophospholipase activity(GO:0004622)
3.8 23.0 GO:0015198 oligopeptide transporter activity(GO:0015198)
3.8 15.2 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
3.7 3.7 GO:0052744 phosphatidylinositol-3-phosphatase activity(GO:0004438) phosphatidylinositol monophosphate phosphatase activity(GO:0052744)
3.6 43.4 GO:0005516 calmodulin binding(GO:0005516)
3.6 21.6 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
3.6 32.2 GO:0000009 alpha-1,6-mannosyltransferase activity(GO:0000009)
3.6 10.7 GO:0043891 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
3.6 3.6 GO:0019003 GDP binding(GO:0019003)
3.5 10.5 GO:0097027 ubiquitin-protein transferase activator activity(GO:0097027)
3.5 24.4 GO:0019201 nucleotide kinase activity(GO:0019201)
3.4 13.6 GO:0016725 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups(GO:0016725) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
3.4 10.1 GO:0070568 guanylyltransferase activity(GO:0070568)
3.4 20.3 GO:0008175 tRNA methyltransferase activity(GO:0008175)
3.3 33.3 GO:0030295 protein kinase activator activity(GO:0030295)
3.3 46.1 GO:0008483 transaminase activity(GO:0008483) transferase activity, transferring nitrogenous groups(GO:0016769)
3.2 35.7 GO:0008135 translation factor activity, RNA binding(GO:0008135)
3.1 3.1 GO:0016774 phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
3.1 9.4 GO:0070567 cytidylyltransferase activity(GO:0070567)
3.1 21.7 GO:0015665 alcohol transmembrane transporter activity(GO:0015665)
3.1 18.4 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
3.1 12.2 GO:0008139 nuclear localization sequence binding(GO:0008139)
3.0 175.9 GO:0003924 GTPase activity(GO:0003924)
2.9 14.5 GO:0008526 phosphatidylcholine transporter activity(GO:0008525) phosphatidylinositol transporter activity(GO:0008526)
2.9 52.1 GO:0019001 GTP binding(GO:0005525) guanyl nucleotide binding(GO:0019001) guanyl ribonucleotide binding(GO:0032561)
2.9 11.5 GO:0004033 aldo-keto reductase (NADP) activity(GO:0004033) alcohol dehydrogenase (NADP+) activity(GO:0008106)
2.8 24.9 GO:0019239 deaminase activity(GO:0019239)
2.7 8.2 GO:0000403 Y-form DNA binding(GO:0000403) guanine/thymine mispair binding(GO:0032137)
2.7 38.2 GO:0070566 adenylyltransferase activity(GO:0070566)
2.7 8.2 GO:0009378 four-way junction helicase activity(GO:0009378)
2.7 13.6 GO:0005338 nucleotide-sugar transmembrane transporter activity(GO:0005338)
2.7 38.1 GO:0001671 ATPase activator activity(GO:0001671)
2.7 8.1 GO:0016880 acid-ammonia (or amide) ligase activity(GO:0016880)
2.6 15.7 GO:0016778 diphosphotransferase activity(GO:0016778)
2.6 10.3 GO:0008762 UDP-N-acetylmuramate dehydrogenase activity(GO:0008762)
2.5 12.7 GO:0008443 phosphofructokinase activity(GO:0008443)
2.5 4.9 GO:0001181 transcription factor activity, core RNA polymerase I binding(GO:0001181)
2.5 14.8 GO:0004022 alcohol dehydrogenase (NAD) activity(GO:0004022)
2.4 4.8 GO:0019205 nucleobase-containing compound kinase activity(GO:0019205)
2.3 18.6 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
2.3 2.3 GO:0003825 alpha,alpha-trehalose-phosphate synthase (UDP-forming) activity(GO:0003825)
2.3 446.0 GO:0003723 RNA binding(GO:0003723)
2.2 9.0 GO:0008310 single-stranded DNA exodeoxyribonuclease activity(GO:0008297) single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
2.2 20.2 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
2.2 60.5 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
2.2 10.8 GO:0017048 Rho GTPase binding(GO:0017048)
2.2 17.3 GO:0004576 oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
2.1 10.7 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
2.1 61.6 GO:0015631 tubulin binding(GO:0015631)
2.1 10.5 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
2.1 6.3 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
2.1 10.4 GO:0060590 ATPase regulator activity(GO:0060590)
2.1 47.4 GO:0017056 structural constituent of nuclear pore(GO:0017056)
2.0 6.0 GO:0004805 trehalose-phosphatase activity(GO:0004805)
2.0 10.0 GO:0008198 ferrous iron binding(GO:0008198)
2.0 9.9 GO:0042124 glucanosyltransferase activity(GO:0042123) 1,3-beta-glucanosyltransferase activity(GO:0042124)
2.0 31.6 GO:0003714 transcription corepressor activity(GO:0003714)
2.0 9.8 GO:0017169 CDP-alcohol phosphatidyltransferase activity(GO:0017169)
1.9 11.6 GO:0001139 transcription factor activity, core RNA polymerase II recruiting(GO:0001139)
1.9 7.4 GO:0004026 alcohol O-acetyltransferase activity(GO:0004026) alcohol O-acyltransferase activity(GO:0034318)
1.8 14.4 GO:0000171 ribonuclease MRP activity(GO:0000171)
1.8 25.1 GO:0015605 organophosphate ester transmembrane transporter activity(GO:0015605)
1.8 12.5 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
1.8 9.0 GO:0000033 alpha-1,3-mannosyltransferase activity(GO:0000033)
1.8 26.7 GO:0008170 N-methyltransferase activity(GO:0008170)
1.8 12.3 GO:0031386 protein tag(GO:0031386)
1.7 7.0 GO:0001167 RNA polymerase I transcription factor activity, sequence-specific DNA binding(GO:0001167)
1.7 8.6 GO:0004707 MAP kinase activity(GO:0004707)
1.7 10.2 GO:0005487 nucleocytoplasmic transporter activity(GO:0005487)
1.6 3.3 GO:0043142 single-stranded DNA-dependent ATPase activity(GO:0043142)
1.6 53.7 GO:0008080 N-acetyltransferase activity(GO:0008080)
1.6 9.7 GO:0016744 transferase activity, transferring aldehyde or ketonic groups(GO:0016744)
1.6 8.0 GO:0015173 aromatic amino acid transmembrane transporter activity(GO:0015173)
1.6 15.9 GO:0043022 ribosome binding(GO:0043022)
1.6 35.0 GO:0015926 glucosidase activity(GO:0015926)
1.6 7.9 GO:0019104 DNA N-glycosylase activity(GO:0019104)
1.6 3.1 GO:0051219 phosphoprotein binding(GO:0051219)
1.5 4.6 GO:0005519 cytoskeletal regulatory protein binding(GO:0005519)
1.5 18.0 GO:0016884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884)
1.5 15.0 GO:0001133 RNA polymerase II transcription factor activity, sequence-specific transcription regulatory region DNA binding(GO:0001133)
1.5 5.9 GO:0015038 glutathione-disulfide reductase activity(GO:0004362) peptide disulfide oxidoreductase activity(GO:0015037) glutathione disulfide oxidoreductase activity(GO:0015038)
1.4 38.9 GO:0051536 iron-sulfur cluster binding(GO:0051536) metal cluster binding(GO:0051540)
1.4 5.8 GO:0001055 RNA polymerase II activity(GO:0001055)
1.4 10.1 GO:0019237 centromeric DNA binding(GO:0019237)
1.4 8.6 GO:0000026 alpha-1,2-mannosyltransferase activity(GO:0000026)
1.4 12.4 GO:0030276 clathrin binding(GO:0030276)
1.4 4.1 GO:0016717 oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water(GO:0016717)
1.3 66.9 GO:0008565 protein transporter activity(GO:0008565)
1.3 8.0 GO:0004029 aldehyde dehydrogenase (NAD) activity(GO:0004029) aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030)
1.3 32.8 GO:0046982 protein heterodimerization activity(GO:0046982)
1.2 11.8 GO:0043495 protein anchor(GO:0043495)
1.2 4.7 GO:0008252 nucleotidase activity(GO:0008252)
1.2 3.5 GO:0019901 protein kinase binding(GO:0019901)
1.2 3.5 GO:0016872 intramolecular lyase activity(GO:0016872)
1.2 4.7 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
1.2 4.7 GO:0004075 biotin carboxylase activity(GO:0004075)
1.1 3.3 GO:0043021 ribonucleoprotein complex binding(GO:0043021)
1.1 4.3 GO:0017137 Rab GTPase binding(GO:0017137)
1.1 6.4 GO:0016776 phosphotransferase activity, phosphate group as acceptor(GO:0016776)
1.0 4.2 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
1.0 3.1 GO:0004100 chitin synthase activity(GO:0004100)
1.0 2.1 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
1.0 22.4 GO:0046983 protein dimerization activity(GO:0046983)
1.0 22.3 GO:0000030 mannosyltransferase activity(GO:0000030)
1.0 16.1 GO:0015616 DNA translocase activity(GO:0015616)
1.0 3.0 GO:0000146 microfilament motor activity(GO:0000146)
1.0 8.9 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.9 2.8 GO:0016832 aldehyde-lyase activity(GO:0016832)
0.9 9.3 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.9 5.4 GO:0019211 phosphatase activator activity(GO:0019211)
0.9 2.7 GO:0008536 Ran GTPase binding(GO:0008536)
0.9 3.5 GO:0017022 myosin binding(GO:0017022)
0.8 2.5 GO:0060589 nucleoside-triphosphatase regulator activity(GO:0060589)
0.8 2.4 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.8 32.4 GO:0005096 GTPase activator activity(GO:0005096)
0.8 3.8 GO:0047429 nucleoside-triphosphate diphosphatase activity(GO:0047429)
0.8 6.8 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.7 2.9 GO:0000991 transcription factor activity, core RNA polymerase II binding(GO:0000991)
0.7 1.4 GO:0030145 manganese ion binding(GO:0030145)
0.7 45.7 GO:0003682 chromatin binding(GO:0003682)
0.7 2.7 GO:0016892 tRNA-intron endonuclease activity(GO:0000213) endoribonuclease activity, producing 3'-phosphomonoesters(GO:0016892)
0.6 1.3 GO:0003906 DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906)
0.6 6.4 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.6 1.8 GO:0000400 four-way junction DNA binding(GO:0000400)
0.6 4.1 GO:0051087 chaperone binding(GO:0051087)
0.6 4.0 GO:0004713 protein tyrosine kinase activity(GO:0004713)
0.6 31.7 GO:0051082 unfolded protein binding(GO:0051082)
0.6 17.3 GO:0043130 ubiquitin binding(GO:0043130)
0.5 1.6 GO:0004629 phospholipase C activity(GO:0004629)
0.5 2.7 GO:0018456 aryl-alcohol dehydrogenase (NAD+) activity(GO:0018456)
0.5 4.7 GO:0004177 aminopeptidase activity(GO:0004177)
0.5 3.6 GO:0004702 receptor signaling protein serine/threonine kinase activity(GO:0004702)
0.5 1.5 GO:0003680 AT DNA binding(GO:0003680)
0.5 1.4 GO:0008144 drug binding(GO:0008144)
0.5 1.4 GO:0050839 cell adhesion molecule binding(GO:0050839)
0.4 3.0 GO:0016742 hydroxymethyl-, formyl- and related transferase activity(GO:0016742)
0.4 3.4 GO:0000182 rDNA binding(GO:0000182)
0.4 1.5 GO:0005034 osmosensor activity(GO:0005034)
0.4 1.1 GO:0016670 oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor(GO:0016670) thiol oxidase activity(GO:0016972)
0.4 10.9 GO:0030674 protein binding, bridging(GO:0030674)
0.4 0.7 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.3 1.0 GO:0004551 nucleotide diphosphatase activity(GO:0004551)
0.3 5.9 GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds(GO:0004553)
0.3 1.3 GO:0051377 mannose-ethanolamine phosphotransferase activity(GO:0051377)
0.3 1.3 GO:0016864 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.3 1.6 GO:0030291 protein serine/threonine kinase inhibitor activity(GO:0030291)
0.3 11.4 GO:0016791 phosphatase activity(GO:0016791)
0.3 1.5 GO:0003923 GPI-anchor transamidase activity(GO:0003923)
0.3 1.8 GO:0000990 transcription factor activity, core RNA polymerase binding(GO:0000990)
0.3 1.7 GO:0005375 copper ion transmembrane transporter activity(GO:0005375)
0.3 1.6 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.2 1.2 GO:0019789 SUMO transferase activity(GO:0019789)
0.2 2.8 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.2 1.2 GO:0008641 small protein activating enzyme activity(GO:0008641)
0.2 5.3 GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds(GO:0016810)
0.2 1.6 GO:0005509 calcium ion binding(GO:0005509)
0.2 1.1 GO:0019904 protein domain specific binding(GO:0019904)
0.2 0.7 GO:0004784 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.2 0.6 GO:0016889 endodeoxyribonuclease activity, producing 3'-phosphomonoesters(GO:0016889)
0.2 1.1 GO:0016859 peptidyl-prolyl cis-trans isomerase activity(GO:0003755) cis-trans isomerase activity(GO:0016859)
0.1 0.8 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.1 1.7 GO:0003774 motor activity(GO:0003774)
0.1 1.3 GO:0005048 signal sequence binding(GO:0005048)
0.1 3.0 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)
0.1 0.3 GO:0032135 heteroduplex DNA loop binding(GO:0000404) DNA insertion or deletion binding(GO:0032135)
0.1 0.7 GO:0043566 structure-specific DNA binding(GO:0043566)
0.1 0.3 GO:0004112 cyclic-nucleotide phosphodiesterase activity(GO:0004112)
0.1 0.7 GO:0005199 structural constituent of cell wall(GO:0005199)
0.0 0.1 GO:0008235 metalloexopeptidase activity(GO:0008235)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
9.8 29.4 PID LKB1 PATHWAY LKB1 signaling events
4.1 12.3 PID CDC42 PATHWAY CDC42 signaling events
3.2 6.4 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
2.8 2.8 PID FOXM1 PATHWAY FOXM1 transcription factor network
2.6 5.3 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
2.6 13.0 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
2.4 7.1 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
2.2 2.2 PID FGF PATHWAY FGF signaling pathway
2.2 21.5 PID ATR PATHWAY ATR signaling pathway
1.9 5.7 PID MYC PATHWAY C-MYC pathway
1.8 9.1 PID PLK1 PATHWAY PLK1 signaling events
1.8 7.2 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
1.7 5.1 PID E2F PATHWAY E2F transcription factor network
1.3 5.3 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.8 5.9 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.7 2.0 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.6 3.0 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.5 1.1 ST FAS SIGNALING PATHWAY Fas Signaling Pathway
0.2 0.9 NABA MATRISOME Ensemble of genes encoding extracellular matrix and extracellular matrix-associated proteins
0.2 0.5 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.1 0.1 PID ERBB4 PATHWAY ErbB4 signaling events
0.0 0.2 PID TELOMERASE PATHWAY Regulation of Telomerase

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
15.6 374.5 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
10.0 59.9 REACTOME LAGGING STRAND SYNTHESIS Genes involved in Lagging Strand Synthesis
9.3 9.3 REACTOME CYTOKINE SIGNALING IN IMMUNE SYSTEM Genes involved in Cytokine Signaling in Immune system
8.6 25.8 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
8.6 25.7 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
7.0 14.1 REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements
6.7 46.8 REACTOME AXON GUIDANCE Genes involved in Axon guidance
6.0 12.0 REACTOME SCF BETA TRCP MEDIATED DEGRADATION OF EMI1 Genes involved in SCF-beta-TrCP mediated degradation of Emi1
5.1 30.6 REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE Genes involved in SRP-dependent cotranslational protein targeting to membrane
5.0 20.0 REACTOME CIRCADIAN CLOCK Genes involved in Circadian Clock
4.8 4.8 REACTOME EXTENSION OF TELOMERES Genes involved in Extension of Telomeres
4.5 18.0 REACTOME INTERFERON SIGNALING Genes involved in Interferon Signaling
4.4 13.3 REACTOME SIGNALLING TO ERKS Genes involved in Signalling to ERKs
4.1 28.8 REACTOME PROTEIN FOLDING Genes involved in Protein folding
3.7 14.9 REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS Genes involved in Glycerophospholipid biosynthesis
2.7 8.2 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
2.6 17.9 REACTOME DNA STRAND ELONGATION Genes involved in DNA strand elongation
2.2 15.5 REACTOME GPCR DOWNSTREAM SIGNALING Genes involved in GPCR downstream signaling
2.0 2.0 REACTOME PLATELET ACTIVATION SIGNALING AND AGGREGATION Genes involved in Platelet activation, signaling and aggregation
2.0 6.0 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
2.0 2.0 REACTOME HOST INTERACTIONS OF HIV FACTORS Genes involved in Host Interactions of HIV factors
1.4 12.2 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
1.3 5.0 REACTOME GLYCOLYSIS Genes involved in Glycolysis
1.2 8.4 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
1.0 2.0 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
1.0 2.0 REACTOME HIV INFECTION Genes involved in HIV Infection
1.0 1.0 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.6 2.5 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.5 2.3 REACTOME TRANSCRIPTION Genes involved in Transcription
0.4 4.0 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.3 1.5 REACTOME GENERIC TRANSCRIPTION PATHWAY Genes involved in Generic Transcription Pathway
0.2 0.5 REACTOME DEVELOPMENTAL BIOLOGY Genes involved in Developmental Biology
0.1 1.7 REACTOME METABOLISM OF LIPIDS AND LIPOPROTEINS Genes involved in Metabolism of lipids and lipoproteins
0.1 0.6 REACTOME G2 M CHECKPOINTS Genes involved in G2/M Checkpoints
0.0 0.3 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination