Results for SNT2
Z-value: 0.73
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Transcription factors associated with SNT2
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
|
SNT2
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S000003099 | DNA binding protein with similarity to the S. pombe Snt2 protein |
Activity-expression correlation:
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| YMR107W Show fit | 9.05 |
Protein required for survival at high temperature during stationary phase; not required for growth on nonfermentable carbon sources |
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| YJR095W Show fit | 5.93 |
Mitochondrial succinate-fumarate transporter, transports succinate into and fumarate out of the mitochondrion; required for ethanol and acetate utilization |
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| YLR327C Show fit | 4.74 |
Protein of unknown function that associates with ribosomes |
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| YIL160C Show fit | 4.25 |
3-ketoacyl-CoA thiolase with broad chain length specificity, cleaves 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA during beta-oxidation of fatty acids |
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| YBL075C Show fit | 3.63 |
ATPase involved in protein folding and the response to stress; plays a role in SRP-dependent cotranslational protein-membrane targeting and translocation; member of the heat shock protein 70 (HSP70) family; localized to the cytoplasm |
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| YJR078W Show fit | 3.44 |
Putative tryptophan 2,3-dioxygenase or indoleamine 2,3-dioxygenase, required for the de novo biosynthesis of NAD from tryptophan via kynurenine; expression regulated by Hst1p and Aft2p |
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| YAL039C Show fit | 3.20 |
Cytochrome c heme lyase (holocytochrome c synthase), attaches heme to apo-cytochrome c (Cyc1p or Cyc7p) in the mitochondrial intermembrane space; human ortholog may have a role in microphthalmia with linear skin defects (MLS) |
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| YOR343C Show fit | 3.05 |
Dubious open reading frame, unlikely to encode a functional protein; based on available experimental and comparative sequence data |
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| YAR050W Show fit | 2.84 |
Lectin-like protein involved in flocculation, cell wall protein that binds to mannose chains on the surface of other cells, confers floc-forming ability that is chymotrypsin sensitive and heat resistant; similar to Flo5p |
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| YHR138C Show fit | 2.60 |
Putative protein of unknown function; has similarity to Pbi2p; double null mutant lacking Pbi2p and Yhr138p exhibits highly fragmented vacuoles |
Network of associatons between targets according to the STRING database.
First level regulatory network of SNT2
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.9 | 5.8 | GO:0015740 | C4-dicarboxylate transport(GO:0015740) |
| 0.4 | 5.1 | GO:0006635 | fatty acid beta-oxidation(GO:0006635) |
| 0.7 | 4.4 | GO:0000128 | flocculation(GO:0000128) flocculation via cell wall protein-carbohydrate interaction(GO:0000501) |
| 0.3 | 3.7 | GO:0019682 | pentose-phosphate shunt(GO:0006098) glyceraldehyde-3-phosphate metabolic process(GO:0019682) |
| 0.4 | 3.6 | GO:0006616 | SRP-dependent cotranslational protein targeting to membrane, translocation(GO:0006616) |
| 0.7 | 3.4 | GO:0034627 | 'de novo' NAD biosynthetic process from tryptophan(GO:0034354) 'de novo' NAD biosynthetic process(GO:0034627) |
| 0.4 | 3.3 | GO:0008614 | pyridoxine metabolic process(GO:0008614) pyridoxine biosynthetic process(GO:0008615) vitamin B6 metabolic process(GO:0042816) vitamin B6 biosynthetic process(GO:0042819) |
| 1.1 | 3.2 | GO:0017006 | protein-heme linkage(GO:0017003) protein-tetrapyrrole linkage(GO:0017006) cytochrome c-heme linkage(GO:0018063) |
| 0.6 | 2.6 | GO:0015804 | neutral amino acid transport(GO:0015804) |
| 0.5 | 2.3 | GO:0015793 | glycerol transport(GO:0015793) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 11.7 | GO:0005743 | mitochondrial inner membrane(GO:0005743) |
| 0.0 | 7.7 | GO:0005739 | mitochondrion(GO:0005739) |
| 0.4 | 4.6 | GO:0031907 | peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907) |
| 0.1 | 3.3 | GO:0031225 | anchored component of membrane(GO:0031225) |
| 0.1 | 2.7 | GO:0042763 | prospore membrane(GO:0005628) intracellular immature spore(GO:0042763) ascospore-type prospore(GO:0042764) |
| 0.1 | 2.2 | GO:0031307 | intrinsic component of mitochondrial outer membrane(GO:0031306) integral component of mitochondrial outer membrane(GO:0031307) |
| 0.1 | 1.8 | GO:0031305 | integral component of mitochondrial inner membrane(GO:0031305) |
| 0.1 | 1.6 | GO:0070469 | respiratory chain(GO:0070469) |
| 0.5 | 1.5 | GO:0031166 | integral component of vacuolar membrane(GO:0031166) |
| 0.3 | 1.4 | GO:0005640 | nuclear outer membrane(GO:0005640) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 6.2 | GO:0016811 | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides(GO:0016811) |
| 1.5 | 5.8 | GO:0015556 | C4-dicarboxylate transmembrane transporter activity(GO:0015556) |
| 1.1 | 4.4 | GO:0005537 | mannose binding(GO:0005537) |
| 0.7 | 4.2 | GO:0016408 | C-acyltransferase activity(GO:0016408) |
| 0.0 | 3.5 | GO:0004674 | protein serine/threonine kinase activity(GO:0004674) |
| 0.4 | 3.1 | GO:0016701 | oxidoreductase activity, acting on single donors with incorporation of molecular oxygen(GO:0016701) oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702) |
| 0.0 | 3.0 | GO:0051082 | unfolded protein binding(GO:0051082) |
| 0.6 | 2.9 | GO:0015295 | solute:proton symporter activity(GO:0015295) |
| 0.1 | 2.8 | GO:0004871 | signal transducer activity(GO:0004871) |
| 0.7 | 2.7 | GO:0015193 | L-proline transmembrane transporter activity(GO:0015193) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 25.8 | PID TELOMERASE PATHWAY | Regulation of Telomerase |
| 0.4 | 1.1 | PID FOXO PATHWAY | FoxO family signaling |
| 0.2 | 0.8 | PID P73PATHWAY | p73 transcription factor network |
| 0.1 | 0.4 | PID MYC ACTIV PATHWAY | Validated targets of C-MYC transcriptional activation |
| 0.1 | 0.3 | PID A6B1 A6B4 INTEGRIN PATHWAY | a6b1 and a6b4 Integrin signaling |
| 0.1 | 0.1 | PID NECTIN PATHWAY | Nectin adhesion pathway |
| 0.1 | 0.1 | PID TCR PATHWAY | TCR signaling in naïve CD4+ T cells |
| 0.0 | 0.1 | PID AR PATHWAY | Coregulation of Androgen receptor activity |
| 0.0 | 0.0 | PID P53 DOWNSTREAM PATHWAY | Direct p53 effectors |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 21.8 | REACTOME CHONDROITIN SULFATE BIOSYNTHESIS | Genes involved in Chondroitin sulfate biosynthesis |
| 1.4 | 4.2 | REACTOME MEIOTIC SYNAPSIS | Genes involved in Meiotic Synapsis |
| 0.1 | 1.3 | REACTOME MEIOSIS | Genes involved in Meiosis |
| 0.1 | 1.0 | REACTOME GLUCONEOGENESIS | Genes involved in Gluconeogenesis |
| 0.1 | 0.3 | REACTOME SHC1 EVENTS IN ERBB4 SIGNALING | Genes involved in SHC1 events in ERBB4 signaling |
| 0.1 | 0.2 | REACTOME AUTODEGRADATION OF CDH1 BY CDH1 APC C | Genes involved in Autodegradation of Cdh1 by Cdh1:APC/C |
| 0.0 | 0.2 | REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION | Genes involved in Antigen processing: Ubiquitination & Proteasome degradation |
| 0.0 | 0.2 | REACTOME DNA REPAIR | Genes involved in DNA Repair |
| 0.0 | 0.2 | REACTOME TRANSCRIPTION | Genes involved in Transcription |
| 0.0 | 0.1 | REACTOME NETRIN1 SIGNALING | Genes involved in Netrin-1 signaling |