Results for SMP1
Z-value: 0.58
Motif logo
Transcription factors associated with SMP1
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
|
SMP1
|
S000000386 | Putative transcription factor of the MADS-box family |
Activity-expression correlation:
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| YDR098C Show fit | 4.27 |
Hydroperoxide and superoxide-radical responsive glutathione-dependent oxidoreductase; monothiol glutaredoxin subfamily member along with Grx4p and Grx5p; protects cells from oxidative damage |
||
| YLR154C Show fit | 2.69 |
Ribonuclease H2 subunit, required for RNase H2 activity |
||
| YJR094W-A Show fit | 2.65 |
Protein component of the large (60S) ribosomal subunit, identical to Rpl43Ap and has similarity to rat L37a ribosomal protein |
||
| YLR388W Show fit | 2.51 |
Protein component of the small (40S) ribosomal subunit; nearly identical to Rps29Bp and has similarity to rat S29 and E. coli S14 ribosomal proteins |
||
| YLR154W-B Show fit | 2.22 |
Dubious open reading frame unlikely to encode a protein; encoded within the the 25S rRNA gene on the opposite strand |
||
| YHR181W Show fit | 2.21 |
Integral membrane protein of the early Golgi apparatus and endoplasmic reticulum, involved in COP II vesicle transport; may also function to promote retention of proteins in the early Golgi compartment |
||
| YEL040W Show fit | 2.18 |
Cell wall protein that functions in the transfer of chitin to beta(1-6)glucan; putative chitin transglycosidase; glycosylphosphatidylinositol (GPI)-anchored protein localized to the bud neck; has a role in cell wall maintenance |
||
| YLR154W-A Show fit | 2.16 |
Dubious open reading frame unlikely to encode a protein; encoded within the the 25S rRNA gene on the opposite strand |
||
| YPR157W Show fit | 2.10 |
Putative protein of unknown function; induced by treatment with 8-methoxypsoralen and UVA irradiation |
||
| YMR116C Show fit | 2.10 |
G-protein beta subunit and guanine nucleotide dissociation inhibitor for Gpa2p; ortholog of RACK1 that inhibits translation; core component of the small (40S) ribosomal subunit; represses Gcn4p in the absence of amino acid starvation |
Network of associatons between targets according to the STRING database.
First level regulatory network of SMP1
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 33.0 | GO:0002181 | cytoplasmic translation(GO:0002181) |
| 0.3 | 5.5 | GO:0051029 | rRNA export from nucleus(GO:0006407) rRNA transport(GO:0051029) |
| 0.0 | 4.2 | GO:0042254 | ribosome biogenesis(GO:0042254) |
| 0.1 | 3.8 | GO:0006879 | cellular iron ion homeostasis(GO:0006879) |
| 0.2 | 3.3 | GO:0006037 | cell wall chitin metabolic process(GO:0006037) |
| 0.4 | 2.9 | GO:0043137 | DNA replication, removal of RNA primer(GO:0043137) |
| 0.7 | 2.8 | GO:0014070 | response to organic cyclic compound(GO:0014070) response to cycloheximide(GO:0046898) |
| 0.2 | 2.5 | GO:0045053 | protein retention in Golgi apparatus(GO:0045053) |
| 0.2 | 2.5 | GO:0042790 | transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:0042790) |
| 0.0 | 2.5 | GO:0042273 | ribosomal large subunit biogenesis(GO:0042273) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 26.1 | GO:0022625 | cytosolic large ribosomal subunit(GO:0022625) |
| 0.3 | 17.6 | GO:0022627 | cytosolic small ribosomal subunit(GO:0022627) |
| 0.0 | 7.6 | GO:0005730 | nucleolus(GO:0005730) |
| 0.0 | 4.1 | GO:0005933 | cellular bud(GO:0005933) |
| 0.1 | 3.4 | GO:0030687 | preribosome, large subunit precursor(GO:0030687) |
| 0.2 | 3.2 | GO:0005736 | DNA-directed RNA polymerase I complex(GO:0005736) |
| 0.9 | 2.8 | GO:0032299 | ribonuclease H2 complex(GO:0032299) |
| 0.1 | 2.8 | GO:0031228 | integral component of Golgi membrane(GO:0030173) intrinsic component of Golgi membrane(GO:0031228) |
| 0.2 | 2.2 | GO:0000144 | cellular bud neck septin ring(GO:0000144) |
| 0.1 | 1.4 | GO:0034399 | nuclear periphery(GO:0034399) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 38.4 | GO:0003735 | structural constituent of ribosome(GO:0003735) |
| 0.0 | 3.8 | GO:0003723 | RNA binding(GO:0003723) |
| 0.2 | 3.3 | GO:0015035 | protein disulfide oxidoreductase activity(GO:0015035) |
| 0.2 | 3.2 | GO:0001054 | RNA polymerase I activity(GO:0001054) |
| 0.7 | 2.8 | GO:0004523 | RNA-DNA hybrid ribonuclease activity(GO:0004523) |
| 0.5 | 2.4 | GO:0005092 | GDP-dissociation inhibitor activity(GO:0005092) |
| 0.1 | 2.3 | GO:0030674 | protein binding, bridging(GO:0030674) |
| 0.4 | 2.2 | GO:0004022 | alcohol dehydrogenase (NAD) activity(GO:0004022) |
| 0.2 | 2.2 | GO:0031386 | protein tag(GO:0031386) |
| 0.2 | 1.8 | GO:0043178 | alcohol binding(GO:0043178) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 1.0 | NABA ECM GLYCOPROTEINS | Genes encoding structural ECM glycoproteins |
| 0.3 | 0.8 | PID SHP2 PATHWAY | SHP2 signaling |
| 0.2 | 0.8 | PID UPA UPAR PATHWAY | Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling |
| 0.2 | 0.7 | PID E2F PATHWAY | E2F transcription factor network |
| 0.1 | 0.4 | PID P73PATHWAY | p73 transcription factor network |
| 0.1 | 0.2 | PID HIF1 TFPATHWAY | HIF-1-alpha transcription factor network |
| 0.0 | 0.2 | PID ATR PATHWAY | ATR signaling pathway |
| 0.1 | 0.1 | PID FOXM1 PATHWAY | FOXM1 transcription factor network |
| 0.1 | 0.1 | PID FGF PATHWAY | FGF signaling pathway |
| 0.0 | 0.1 | PID AVB3 INTEGRIN PATHWAY | Integrins in angiogenesis |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 3.9 | REACTOME 3 UTR MEDIATED TRANSLATIONAL REGULATION | Genes involved in 3' -UTR-mediated translational regulation |
| 0.3 | 2.3 | REACTOME ACTIVATION OF THE MRNA UPON BINDING OF THE CAP BINDING COMPLEX AND EIFS AND SUBSEQUENT BINDING TO 43S | Genes involved in Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S |
| 0.3 | 1.0 | REACTOME SIGNALLING TO ERKS | Genes involved in Signalling to ERKs |
| 0.2 | 0.8 | REACTOME CLASS A1 RHODOPSIN LIKE RECEPTORS | Genes involved in Class A/1 (Rhodopsin-like receptors) |
| 0.1 | 0.7 | REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC | Genes involved in Formation of tubulin folding intermediates by CCT/TriC |
| 0.2 | 0.6 | REACTOME G1 S SPECIFIC TRANSCRIPTION | Genes involved in G1/S-Specific Transcription |
| 0.2 | 0.6 | REACTOME GLYCOLYSIS | Genes involved in Glycolysis |
| 0.1 | 0.6 | REACTOME LAGGING STRAND SYNTHESIS | Genes involved in Lagging Strand Synthesis |
| 0.0 | 0.4 | REACTOME MITOTIC PROMETAPHASE | Genes involved in Mitotic Prometaphase |
| 0.0 | 0.3 | REACTOME METABOLISM OF MRNA | Genes involved in Metabolism of mRNA |