Results for RSC30
Z-value: 0.67
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Transcription factors associated with RSC30
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
|
RSC30
|
S000001098 | Component of the RSC chromatin remodeling complex |
Activity-expression correlation:
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| YOR348C Show fit | 6.74 |
Proline permease, required for high-affinity transport of proline; also transports the toxic proline analog azetidine-2-carboxylate (AzC); PUT4 transcription is repressed in ammonia-grown cells |
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| YIL057C Show fit | 3.52 |
Putative protein of unknown function; expression induced under carbon limitation and repressed under high glucose |
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| YGR067C Show fit | 3.22 |
Putative protein of unknown function; contains a zinc finger motif similar to that of Adr1p |
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| YJR115W Show fit | 2.69 |
Putative protein of unknown function |
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| YOR345C Show fit | 2.69 |
Dubious ORF unlikely to encode a protein, based on available experimental and comparative sequence data; overlaps the verified gene REV1; null mutant displays increased resistance to antifungal agents gliotoxin, cycloheximide and H2O2 |
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| YKL109W Show fit | 2.68 |
Subunit of the heme-activated, glucose-repressed Hap2p/3p/4p/5p CCAAT-binding complex, a transcriptional activator and global regulator of respiratory gene expression; provides the principal activation function of the complex |
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| YML089C Show fit | 2.63 |
Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data; expression induced by calcium shortage |
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| YGL062W Show fit | 2.58 |
Pyruvate carboxylase isoform, cytoplasmic enzyme that converts pyruvate to oxaloacetate; highly similar to isoform Pyc2p but differentially regulated; mutations in the human homolog are associated with lactic acidosis |
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| YPL026C Show fit | 2.55 |
Putative serine/threonine protein kinase; involved in the adaptation to low concentrations of glucose independent of the SNF3 regulated pathway |
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| YOR346W Show fit | 2.53 |
Deoxycytidyl transferase, forms a complex with the subunits of DNA polymerase zeta, Rev3p and Rev7p; involved in repair of abasic sites in damaged DNA |
Network of associatons between targets according to the STRING database.
First level regulatory network of RSC30
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.7 | 6.8 | GO:0015804 | neutral amino acid transport(GO:0015804) |
| 1.4 | 4.1 | GO:0015888 | thiamine transport(GO:0015888) |
| 0.4 | 3.9 | GO:0006097 | glyoxylate cycle(GO:0006097) |
| 0.3 | 3.3 | GO:0015758 | glucose transport(GO:0015758) |
| 0.5 | 3.0 | GO:0000128 | flocculation(GO:0000128) flocculation via cell wall protein-carbohydrate interaction(GO:0000501) |
| 0.4 | 2.6 | GO:0043457 | regulation of cellular respiration(GO:0043457) |
| 0.3 | 2.5 | GO:0070987 | error-free translesion synthesis(GO:0070987) |
| 0.2 | 2.5 | GO:0006122 | mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122) |
| 0.6 | 2.4 | GO:0043388 | positive regulation of DNA binding(GO:0043388) regulation of DNA binding(GO:0051101) |
| 0.1 | 2.3 | GO:0070591 | ascospore wall assembly(GO:0030476) spore wall assembly(GO:0042244) spore wall biogenesis(GO:0070590) ascospore wall biogenesis(GO:0070591) fungal-type cell wall assembly(GO:0071940) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 7.1 | GO:0005743 | mitochondrial inner membrane(GO:0005743) |
| 0.0 | 3.1 | GO:0098852 | fungal-type vacuole membrane(GO:0000329) lytic vacuole membrane(GO:0098852) |
| 0.4 | 2.8 | GO:0034657 | GID complex(GO:0034657) |
| 0.7 | 2.7 | GO:0016602 | CCAAT-binding factor complex(GO:0016602) |
| 0.3 | 2.4 | GO:0045263 | mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276) proton-transporting ATP synthase complex, coupling factor F(o)(GO:0045263) |
| 0.8 | 2.3 | GO:0031422 | RecQ helicase-Topo III complex(GO:0031422) |
| 0.0 | 2.3 | GO:0005759 | mitochondrial matrix(GO:0005759) |
| 0.1 | 2.1 | GO:0070469 | respiratory chain(GO:0070469) |
| 0.2 | 1.9 | GO:0005750 | mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275) |
| 0.1 | 1.9 | GO:0042763 | prospore membrane(GO:0005628) intracellular immature spore(GO:0042763) ascospore-type prospore(GO:0042764) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.5 | 6.1 | GO:0015193 | L-proline transmembrane transporter activity(GO:0015193) |
| 0.5 | 5.0 | GO:0015205 | nucleobase transmembrane transporter activity(GO:0015205) |
| 0.0 | 3.9 | GO:0000981 | RNA polymerase II transcription factor activity, sequence-specific DNA binding(GO:0000981) |
| 0.1 | 3.6 | GO:0003684 | damaged DNA binding(GO:0003684) |
| 0.8 | 3.1 | GO:0005537 | mannose binding(GO:0005537) |
| 0.2 | 3.0 | GO:0001102 | RNA polymerase II activating transcription factor binding(GO:0001102) |
| 0.2 | 2.7 | GO:0046933 | proton-transporting ATP synthase activity, rotational mechanism(GO:0046933) |
| 0.4 | 2.3 | GO:0000400 | four-way junction DNA binding(GO:0000400) |
| 0.3 | 2.1 | GO:0016833 | oxo-acid-lyase activity(GO:0016833) |
| 0.6 | 1.9 | GO:0016289 | CoA hydrolase activity(GO:0016289) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 29.3 | PID TELOMERASE PATHWAY | Regulation of Telomerase |
| 0.3 | 2.3 | PID FANCONI PATHWAY | Fanconi anemia pathway |
| 0.5 | 1.6 | PID IL4 2PATHWAY | IL4-mediated signaling events |
| 0.3 | 0.8 | PID ERBB2 ERBB3 PATHWAY | ErbB2/ErbB3 signaling events |
| 0.2 | 0.8 | PID ERA GENOMIC PATHWAY | Validated nuclear estrogen receptor alpha network |
| 0.2 | 0.6 | PID HNF3B PATHWAY | FOXA2 and FOXA3 transcription factor networks |
| 0.5 | 0.5 | PID TCR PATHWAY | TCR signaling in naïve CD4+ T cells |
| 0.2 | 0.4 | PID ANGIOPOIETIN RECEPTOR PATHWAY | Angiopoietin receptor Tie2-mediated signaling |
| 0.0 | 0.0 | SA G1 AND S PHASES | Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition. |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 29.2 | REACTOME CHONDROITIN SULFATE BIOSYNTHESIS | Genes involved in Chondroitin sulfate biosynthesis |
| 0.2 | 2.7 | REACTOME DNA REPAIR | Genes involved in DNA Repair |
| 0.2 | 1.7 | REACTOME GLUCONEOGENESIS | Genes involved in Gluconeogenesis |
| 0.3 | 0.9 | REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS | Genes involved in Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. |
| 0.2 | 0.9 | REACTOME BIOLOGICAL OXIDATIONS | Genes involved in Biological oxidations |
| 0.4 | 0.8 | REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S | Genes involved in Activation of Chaperone Genes by XBP1(S) |
| 0.3 | 0.8 | REACTOME PI3K EVENTS IN ERBB2 SIGNALING | Genes involved in PI3K events in ERBB2 signaling |
| 0.1 | 0.6 | REACTOME MEIOTIC RECOMBINATION | Genes involved in Meiotic Recombination |
| 0.1 | 0.5 | REACTOME AUTODEGRADATION OF CDH1 BY CDH1 APC C | Genes involved in Autodegradation of Cdh1 by Cdh1:APC/C |
| 0.0 | 0.4 | REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES | Genes involved in Metabolism of amino acids and derivatives |