Results for RSC3
Z-value: 1.64
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Transcription factors associated with RSC3
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
|
RSC3
|
S000002711 | Component of the RSC chromatin remodeling complex |
Activity-expression correlation:
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| YGR108W Show fit | 14.05 |
B-type cyclin involved in cell cycle progression; activates Cdc28p to promote the transition from G2 to M phase; accumulates during G2 and M, then targeted via a destruction box motif for ubiquitin-mediated degradation by the proteasome |
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| YCR018C Show fit | 12.99 |
Protein involved in the processing of pre-rRNA to mature rRNA; contains a C2/C2 zinc finger motif; srd1 mutation suppresses defects caused by the rrp1-1 mutation |
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| YOL086C Show fit | 11.93 |
Alcohol dehydrogenase, fermentative isozyme active as homo- or heterotetramers; required for the reduction of acetaldehyde to ethanol, the last step in the glycolytic pathway |
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| YJL190C Show fit | 10.64 |
Protein component of the small (40S) ribosomal subunit; nearly identical to Rps22Bp and has similarity to E. coli S8 and rat S15a ribosomal proteins |
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| YJR094W-A Show fit | 10.14 |
Protein component of the large (60S) ribosomal subunit, identical to Rpl43Ap and has similarity to rat L37a ribosomal protein |
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| YPL250W-A Show fit | 9.41 |
Identified by fungal homology and RT-PCR |
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| YDL023C Show fit | 9.37 |
Dubious open reading frame, unlikely to encode a protein; not conserved in other Saccharomyces species; overlaps the verified gene GPD1; deletion confers sensitivity to GSAO; deletion in cyr1 mutant results in loss of stress resistance |
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| YKL096W-A Show fit | 9.17 |
Covalently linked cell wall mannoprotein, major constituent of the cell wall; plays a role in stabilizing the cell wall; involved in low pH resistance; precursor is GPI-anchored |
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| YDR133C Show fit | 8.56 |
Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps YDR134C |
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| YGL148W Show fit | 8.38 |
Bifunctional chorismate synthase and flavin reductase, catalyzes the conversion of 5-enolpyruvylshikimate 3-phosphate (EPSP) to form chorismate, which is a precursor to aromatic amino acids |
Network of associatons between targets according to the STRING database.
First level regulatory network of RSC3
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.7 | 89.0 | GO:0002181 | cytoplasmic translation(GO:0002181) |
| 0.2 | 29.1 | GO:0006364 | rRNA processing(GO:0006364) |
| 1.3 | 24.0 | GO:0006407 | rRNA export from nucleus(GO:0006407) rRNA transport(GO:0051029) |
| 2.0 | 19.9 | GO:0006116 | NADH oxidation(GO:0006116) |
| 0.5 | 15.2 | GO:0046939 | nucleotide phosphorylation(GO:0046939) |
| 3.1 | 12.4 | GO:0035337 | fatty-acyl-CoA metabolic process(GO:0035337) |
| 1.7 | 11.8 | GO:0010696 | positive regulation of spindle pole body separation(GO:0010696) |
| 0.5 | 11.3 | GO:0002098 | tRNA wobble base modification(GO:0002097) tRNA wobble uridine modification(GO:0002098) |
| 0.7 | 10.5 | GO:0006450 | regulation of translational fidelity(GO:0006450) |
| 0.7 | 10.3 | GO:0000028 | ribosomal small subunit assembly(GO:0000028) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.8 | 68.7 | GO:0022625 | cytosolic large ribosomal subunit(GO:0022625) |
| 1.1 | 65.2 | GO:0022627 | cytosolic small ribosomal subunit(GO:0022627) |
| 0.2 | 16.9 | GO:0005576 | extracellular region(GO:0005576) |
| 1.4 | 16.3 | GO:0000788 | nuclear nucleosome(GO:0000788) |
| 0.1 | 12.9 | GO:0005933 | cellular bud(GO:0005933) |
| 0.6 | 10.0 | GO:0000307 | cyclin-dependent protein kinase holoenzyme complex(GO:0000307) |
| 0.3 | 9.5 | GO:0005811 | lipid particle(GO:0005811) |
| 0.0 | 8.7 | GO:0005789 | endoplasmic reticulum membrane(GO:0005789) |
| 2.5 | 7.6 | GO:0009331 | glycerol-3-phosphate dehydrogenase complex(GO:0009331) |
| 2.3 | 6.8 | GO:0032299 | ribonuclease H2 complex(GO:0032299) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.6 | 129.3 | GO:0003735 | structural constituent of ribosome(GO:0003735) |
| 0.6 | 18.6 | GO:0046982 | protein heterodimerization activity(GO:0046982) |
| 0.6 | 14.8 | GO:0016538 | cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538) |
| 2.0 | 12.0 | GO:0004022 | alcohol dehydrogenase (NAD) activity(GO:0004022) |
| 0.9 | 11.1 | GO:0005199 | structural constituent of cell wall(GO:0005199) |
| 0.3 | 10.1 | GO:0004722 | protein serine/threonine phosphatase activity(GO:0004722) |
| 3.3 | 9.9 | GO:0051219 | phosphoprotein binding(GO:0051219) |
| 2.4 | 9.4 | GO:0004467 | long-chain fatty acid-CoA ligase activity(GO:0004467) |
| 0.9 | 9.1 | GO:0001133 | RNA polymerase II transcription factor activity, sequence-specific transcription regulatory region DNA binding(GO:0001133) |
| 0.9 | 9.1 | GO:0031386 | protein tag(GO:0031386) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.5 | 2.7 | PID CXCR4 PATHWAY | CXCR4-mediated signaling events |
| 0.4 | 2.1 | PID PLK1 PATHWAY | PLK1 signaling events |
| 0.2 | 1.6 | PID ATR PATHWAY | ATR signaling pathway |
| 0.2 | 0.7 | PID HIF1 TFPATHWAY | HIF-1-alpha transcription factor network |
| 0.3 | 0.6 | ST FAS SIGNALING PATHWAY | Fas Signaling Pathway |
| 0.1 | 0.3 | PID E2F PATHWAY | E2F transcription factor network |
| 0.1 | 0.3 | PID ERA GENOMIC PATHWAY | Validated nuclear estrogen receptor alpha network |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.8 | 14.1 | REACTOME ACTIVATION OF THE MRNA UPON BINDING OF THE CAP BINDING COMPLEX AND EIFS AND SUBSEQUENT BINDING TO 43S | Genes involved in Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S |
| 2.0 | 7.9 | REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS | Genes involved in Glycerophospholipid biosynthesis |
| 0.8 | 6.0 | REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE | Genes involved in mRNA Decay by 5' to 3' Exoribonuclease |
| 0.8 | 5.5 | REACTOME UNWINDING OF DNA | Genes involved in Unwinding of DNA |
| 1.1 | 4.5 | REACTOME GLYCOLYSIS | Genes involved in Glycolysis |
| 0.2 | 2.8 | REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX | Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex |
| 0.3 | 2.6 | REACTOME PPARA ACTIVATES GENE EXPRESSION | Genes involved in PPARA Activates Gene Expression |
| 0.2 | 2.2 | REACTOME MITOTIC PROMETAPHASE | Genes involved in Mitotic Prometaphase |
| 0.2 | 1.3 | REACTOME PROTEIN FOLDING | Genes involved in Protein folding |
| 0.2 | 1.0 | REACTOME GLOBAL GENOMIC NER GG NER | Genes involved in Global Genomic NER (GG-NER) |