Results for RLM1
Z-value: 1.13
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Transcription factors associated with RLM1
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
|
RLM1
|
S000006010 | MADS-box transcription factor |
Activity-expression correlation:
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| YHR212C Show fit | 6.14 |
Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data |
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| YMR013C Show fit | 6.08 |
Dolichol kinase, catalyzes the terminal step in dolichyl monophosphate (Dol-P) biosynthesis; required for viability and for normal rates of lipid intermediate synthesis and protein N-glycosylation |
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| YHR212W-A Show fit | 5.96 |
Putative protein of unknown function; identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching |
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| YAR053W Show fit | 5.74 |
Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data |
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| YKR097W Show fit | 5.72 |
Phosphoenolpyruvate carboxykinase, key enzyme in gluconeogenesis, catalyzes early reaction in carbohydrate biosynthesis, glucose represses transcription and accelerates mRNA degradation, regulated by Mcm1p and Cat8p, located in the cytosol |
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| YAL062W Show fit | 5.48 |
NADP(+)-dependent glutamate dehydrogenase, synthesizes glutamate from ammonia and alpha-ketoglutarate; rate of alpha-ketoglutarate utilization differs from Gdh1p; expression regulated by nitrogen and carbon sources |
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| YIL125W Show fit | 5.01 |
Component of the mitochondrial alpha-ketoglutarate dehydrogenase complex, which catalyzes a key step in the tricarboxylic acid (TCA) cycle, the oxidative decarboxylation of alpha-ketoglutarate to form succinyl-CoA |
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| YPL171C Show fit | 4.87 |
Widely conserved NADPH oxidoreductase containing flavin mononucleotide (FMN), homologous to Oye2p with slight differences in ligand binding and catalytic properties; may be involved in sterol metabolism |
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| YAR060C Show fit | 4.64 |
Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data |
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| YOR120W Show fit | 4.48 |
Putative NADP(+) coupled glycerol dehydrogenase, proposed to be involved in an alternative pathway for glycerol catabolism; member of the aldo-keto reductase (AKR) family |
Network of associatons between targets according to the STRING database.
First level regulatory network of RLM1
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.7 | 10.4 | GO:0000501 | flocculation(GO:0000128) flocculation via cell wall protein-carbohydrate interaction(GO:0000501) |
| 0.5 | 8.1 | GO:0006772 | thiamine metabolic process(GO:0006772) |
| 0.4 | 7.6 | GO:0015749 | hexose transport(GO:0008645) monosaccharide transport(GO:0015749) |
| 0.3 | 7.5 | GO:0006094 | gluconeogenesis(GO:0006094) |
| 1.5 | 5.9 | GO:0006103 | 2-oxoglutarate metabolic process(GO:0006103) |
| 1.9 | 5.7 | GO:0015755 | fructose transport(GO:0015755) |
| 0.2 | 5.5 | GO:0006915 | apoptotic process(GO:0006915) cell death(GO:0008219) programmed cell death(GO:0012501) |
| 1.6 | 4.9 | GO:0019676 | ammonia assimilation cycle(GO:0019676) |
| 1.5 | 4.6 | GO:0042843 | D-xylose catabolic process(GO:0042843) |
| 0.5 | 4.5 | GO:0045721 | negative regulation of gluconeogenesis(GO:0045721) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 18.7 | GO:0031224 | intrinsic component of membrane(GO:0031224) |
| 0.0 | 5.7 | GO:0005743 | mitochondrial inner membrane(GO:0005743) |
| 1.8 | 5.4 | GO:0009353 | mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947) mitochondrial oxoglutarate dehydrogenase complex(GO:0009353) dihydrolipoyl dehydrogenase complex(GO:0045240) oxoglutarate dehydrogenase complex(GO:0045252) |
| 0.2 | 5.4 | GO:0005770 | late endosome(GO:0005770) |
| 0.1 | 4.1 | GO:0031225 | anchored component of membrane(GO:0031225) |
| 0.0 | 3.3 | GO:0098852 | fungal-type vacuole membrane(GO:0000329) lytic vacuole membrane(GO:0098852) |
| 0.3 | 3.1 | GO:0045277 | mitochondrial respiratory chain complex IV(GO:0005751) respiratory chain complex IV(GO:0045277) |
| 0.1 | 3.0 | GO:0000315 | organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762) |
| 0.8 | 2.5 | GO:0030061 | mitochondrial crista(GO:0030061) |
| 0.6 | 2.4 | GO:0000148 | 1,3-beta-D-glucan synthase complex(GO:0000148) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 2.6 | 10.4 | GO:0005537 | mannose binding(GO:0005537) |
| 0.3 | 7.9 | GO:0016881 | acid-amino acid ligase activity(GO:0016881) |
| 1.5 | 7.7 | GO:0015295 | solute:proton symporter activity(GO:0015295) |
| 0.4 | 7.0 | GO:0016831 | carboxy-lyase activity(GO:0016831) |
| 0.8 | 6.9 | GO:0000293 | ferric-chelate reductase activity(GO:0000293) oxidoreductase activity, oxidizing metal ions, NAD or NADP as acceptor(GO:0016723) |
| 1.3 | 5.4 | GO:0016639 | oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor(GO:0016639) |
| 1.3 | 5.2 | GO:0016624 | oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor(GO:0016624) |
| 1.2 | 4.7 | GO:0016661 | oxidoreductase activity, acting on other nitrogenous compounds as donors(GO:0016661) |
| 1.2 | 4.6 | GO:0004032 | alditol:NADP+ 1-oxidoreductase activity(GO:0004032) |
| 0.4 | 4.4 | GO:0015578 | fructose transmembrane transporter activity(GO:0005353) mannose transmembrane transporter activity(GO:0015578) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 124.3 | ST PAC1 RECEPTOR PATHWAY | PAC1 Receptor Pathway |
| 1.8 | 5.5 | PID HNF3B PATHWAY | FOXA2 and FOXA3 transcription factor networks |
| 0.5 | 2.1 | PID DELTA NP63 PATHWAY | Validated transcriptional targets of deltaNp63 isoforms |
| 0.4 | 1.2 | PID IL4 2PATHWAY | IL4-mediated signaling events |
| 0.2 | 0.6 | PID AR PATHWAY | Coregulation of Androgen receptor activity |
| 0.1 | 0.4 | PID ATM PATHWAY | ATM pathway |
| 0.1 | 0.3 | NABA ECM REGULATORS | Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix |
| 0.1 | 0.2 | PID INTEGRIN A4B1 PATHWAY | Alpha4 beta1 integrin signaling events |
| 0.0 | 0.2 | PID TELOMERASE PATHWAY | Regulation of Telomerase |
| 0.1 | 0.1 | PID TCPTP PATHWAY | Signaling events mediated by TCPTP |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 124.3 | REACTOME CHONDROITIN SULFATE BIOSYNTHESIS | Genes involved in Chondroitin sulfate biosynthesis |
| 0.8 | 7.1 | REACTOME GLUCONEOGENESIS | Genes involved in Gluconeogenesis |
| 0.7 | 2.0 | REACTOME SHC1 EVENTS IN ERBB4 SIGNALING | Genes involved in SHC1 events in ERBB4 signaling |
| 0.3 | 0.8 | REACTOME DNA REPAIR | Genes involved in DNA Repair |
| 0.2 | 0.7 | REACTOME RESPIRATORY ELECTRON TRANSPORT | Genes involved in Respiratory electron transport |
| 0.2 | 0.6 | REACTOME BIOLOGICAL OXIDATIONS | Genes involved in Biological oxidations |
| 0.1 | 0.6 | REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION | Genes involved in E2F-enabled inhibition of pre-replication complex formation |
| 0.2 | 0.5 | REACTOME MEIOTIC SYNAPSIS | Genes involved in Meiotic Synapsis |
| 0.1 | 0.4 | REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS | Genes involved in Homologous recombination repair of replication-independent double-strand breaks |
| 0.1 | 0.2 | REACTOME GLUCOSE METABOLISM | Genes involved in Glucose metabolism |