Results for RGM1
Z-value: 0.91
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Transcription factors associated with RGM1
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
|
RGM1
|
S000004794 | Putative zinc finger DNA binding transcription factor |
Activity-expression correlation:
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| YMR107W Show fit | 17.41 |
Protein required for survival at high temperature during stationary phase; not required for growth on nonfermentable carbon sources |
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| YMR175W Show fit | 13.70 |
Protein of unknown function whose expression is induced by osmotic stress |
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| YOL052C-A Show fit | 10.79 |
Multistress response protein, expression is activated by a variety of xenobiotic agents and environmental or physiological stresses |
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| YKL217W Show fit | 9.80 |
Lactate transporter, required for uptake of lactate and pyruvate; phosphorylated; expression is derepressed by transcriptional activator Cat8p during respiratory growth, and repressed in the presence of glucose, fructose, and mannose |
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| YNR034W-A Show fit | 9.53 |
Putative protein of unknown function; expression is regulated by Msn2p/Msn4p |
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| YHR096C Show fit | 8.88 |
Hexose transporter with moderate affinity for glucose, induced in the presence of non-fermentable carbon sources, induced by a decrease in growth rate, contains an extended N-terminal domain relative to other HXTs |
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| YOR393W Show fit | 8.31 |
Protein of unknown function, has similarity to enolases |
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| YEL039C Show fit | 7.87 |
Cytochrome c isoform 2, expressed under hypoxic conditions; electron carrier of the mitochondrial intermembrane space that transfers electrons from ubiquinone-cytochrome c oxidoreductase to cytochrome c oxidase during cellular respiration |
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| YKL026C Show fit | 7.64 |
Phospholipid hydroperoxide glutathione peroxidase induced by glucose starvation that protects cells from phospholipid hydroperoxides and nonphospholipid peroxides during oxidative stress |
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| YPL230W Show fit | 7.53 |
Putative transcription factor containing a C2H2 zinc finger; mutation affects transcriptional regulation of genes involved in protein folding, ATP binding, and cell wall biosynthesis |
Network of associatons between targets according to the STRING database.
First level regulatory network of RGM1
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.9 | 18.8 | GO:0006122 | mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122) |
| 4.4 | 17.5 | GO:0006848 | pyruvate transport(GO:0006848) |
| 1.3 | 16.8 | GO:0051156 | glucose 6-phosphate metabolic process(GO:0051156) |
| 1.7 | 15.6 | GO:0006097 | glyoxylate cycle(GO:0006097) |
| 1.0 | 15.3 | GO:0005978 | glycogen biosynthetic process(GO:0005978) |
| 1.0 | 15.3 | GO:0006754 | ATP biosynthetic process(GO:0006754) |
| 3.1 | 12.3 | GO:0071462 | response to water(GO:0009415) cellular response to water stimulus(GO:0071462) |
| 2.2 | 10.8 | GO:0005980 | glycogen catabolic process(GO:0005980) |
| 3.5 | 10.5 | GO:0052547 | negative regulation of peptidase activity(GO:0010466) regulation of peptidase activity(GO:0052547) |
| 0.6 | 9.9 | GO:0006094 | gluconeogenesis(GO:0006094) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 57.6 | GO:0005739 | mitochondrion(GO:0005739) |
| 0.2 | 36.2 | GO:0000324 | storage vacuole(GO:0000322) lytic vacuole(GO:0000323) fungal-type vacuole(GO:0000324) |
| 0.2 | 30.6 | GO:0005743 | mitochondrial inner membrane(GO:0005743) |
| 0.3 | 14.9 | GO:0005758 | mitochondrial intermembrane space(GO:0005758) |
| 1.1 | 14.1 | GO:0070469 | respiratory chain(GO:0070469) |
| 0.8 | 14.1 | GO:0031307 | intrinsic component of mitochondrial outer membrane(GO:0031306) integral component of mitochondrial outer membrane(GO:0031307) |
| 0.2 | 11.2 | GO:0031225 | anchored component of membrane(GO:0031225) |
| 1.2 | 10.5 | GO:0005750 | mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275) |
| 3.0 | 8.9 | GO:0000015 | phosphopyruvate hydratase complex(GO:0000015) |
| 0.9 | 7.8 | GO:0000328 | fungal-type vacuole lumen(GO:0000328) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 20.6 | GO:0051082 | unfolded protein binding(GO:0051082) |
| 0.9 | 14.8 | GO:0020037 | heme binding(GO:0020037) tetrapyrrole binding(GO:0046906) |
| 2.9 | 14.7 | GO:0015295 | solute:proton symporter activity(GO:0015295) |
| 0.8 | 10.7 | GO:0005353 | fructose transmembrane transporter activity(GO:0005353) mannose transmembrane transporter activity(GO:0015578) |
| 3.5 | 10.5 | GO:0030414 | endopeptidase inhibitor activity(GO:0004866) peptidase inhibitor activity(GO:0030414) |
| 1.3 | 10.2 | GO:0016681 | ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681) |
| 0.3 | 10.2 | GO:0004553 | hydrolase activity, hydrolyzing O-glycosyl compounds(GO:0004553) |
| 0.8 | 9.1 | GO:0046933 | proton-transporting ATP synthase activity, rotational mechanism(GO:0046933) |
| 3.0 | 8.9 | GO:0004634 | phosphopyruvate hydratase activity(GO:0004634) |
| 2.7 | 8.1 | GO:0004092 | carnitine O-acetyltransferase activity(GO:0004092) carnitine O-acyltransferase activity(GO:0016406) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 58.4 | PID P53 DOWNSTREAM PATHWAY | Direct p53 effectors |
| 2.4 | 7.3 | PID IL4 2PATHWAY | IL4-mediated signaling events |
| 1.0 | 5.0 | PID ERA GENOMIC PATHWAY | Validated nuclear estrogen receptor alpha network |
| 1.4 | 4.1 | PID HNF3B PATHWAY | FOXA2 and FOXA3 transcription factor networks |
| 0.4 | 2.2 | PID MYC ACTIV PATHWAY | Validated targets of C-MYC transcriptional activation |
| 0.4 | 1.7 | PID DELTA NP63 PATHWAY | Validated transcriptional targets of deltaNp63 isoforms |
| 0.6 | 1.3 | PID EPHA2 FWD PATHWAY | EPHA2 forward signaling |
| 0.4 | 1.2 | PID FOXO PATHWAY | FoxO family signaling |
| 0.1 | 0.5 | PID PLK1 PATHWAY | PLK1 signaling events |
| 0.1 | 0.3 | PID P73PATHWAY | p73 transcription factor network |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 50.8 | REACTOME CHONDROITIN SULFATE BIOSYNTHESIS | Genes involved in Chondroitin sulfate biosynthesis |
| 1.4 | 15.9 | REACTOME GLUCOSE METABOLISM | Genes involved in Glucose metabolism |
| 2.2 | 6.7 | REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S | Genes involved in Activation of Chaperone Genes by XBP1(S) |
| 0.7 | 2.0 | REACTOME MEIOTIC SYNAPSIS | Genes involved in Meiotic Synapsis |
| 0.3 | 1.4 | REACTOME DOUBLE STRAND BREAK REPAIR | Genes involved in Double-Strand Break Repair |
| 0.2 | 1.4 | REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES | Genes involved in Metabolism of amino acids and derivatives |
| 0.3 | 1.0 | REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS | Genes involved in Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. |
| 0.4 | 0.7 | REACTOME SHC1 EVENTS IN ERBB4 SIGNALING | Genes involved in SHC1 events in ERBB4 signaling |
| 0.2 | 0.6 | REACTOME ETHANOL OXIDATION | Genes involved in Ethanol oxidation |
| 0.1 | 0.1 | REACTOME PLATELET ACTIVATION SIGNALING AND AGGREGATION | Genes involved in Platelet activation, signaling and aggregation |