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Results for REB1

Z-value: 0.92

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Transcription factors associated with REB1

Gene Symbol Gene ID Gene Info
REB1
S000000253 RNA polymerase I enhancer binding protein

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
REB1YBR049C0.601.1e-03Click!

Activity profile of REB1 motif

Sorted Z-values of REB1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
YLR154W-A 5.41 Dubious open reading frame unlikely to encode a protein; encoded within the the 25S rRNA gene on the opposite strand
YLR154W-B 4.83 Dubious open reading frame unlikely to encode a protein; encoded within the the 25S rRNA gene on the opposite strand
YLR154W-C 4.04
TAR1
Mitochondrial protein of unknown function, overexpression suppresses an rpo41 mutation affecting mitochondrial RNA polymerase; encoded within the 25S rRNA gene on the opposite strand
YNR013C 3.55
PHO91
Low-affinity phosphate transporter of the vacuolar membrane; deletion of pho84, pho87, pho89, pho90, and pho91 causes synthetic lethality; transcription independent of Pi and Pho4p activity; overexpression results in vigorous growth
YGR242W 3.08 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified ORF YAP1802/YGR241C
YFL015W-A 2.95 Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data
YGR241C 2.58
YAP1802
Protein involved in clathrin cage assembly; binds Pan1p and clathrin; homologous to Yap1801p, member of the AP180 protein family
YLR154C 2.56
RNH203
Ribonuclease H2 subunit, required for RNase H2 activity
YCR031C 2.55
RPS14A
Ribosomal protein 59 of the small subunit, required for ribosome assembly and 20S pre-rRNA processing; mutations confer cryptopleurine resistance; nearly identical to Rps14Bp and similar to E. coli S11 and rat S14 ribosomal proteins
YFL015C 2.48 Dubious open reading frame unlikely to encode a protein; partially overlaps dubious ORF YFL015W-A; YFL015C is not an essential gene
YER131W 2.31
RPS26B
Protein component of the small (40S) ribosomal subunit; nearly identical to Rps26Ap and has similarity to rat S26 ribosomal protein
YLR162W-A 2.26 Putative protein of unknown function identified by fungal homology comparisons and RT-PCR
YGR265W 2.25 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified ORF MES1/YGR264C, which encodes methionyl-tRNA synthetase
YOL005C 2.13
RPB11
RNA polymerase II subunit B12.5; part of central core; similar to Rpc19p and bacterial alpha subunit
YOL086C 2.04
ADH1
Alcohol dehydrogenase, fermentative isozyme active as homo- or heterotetramers; required for the reduction of acetaldehyde to ethanol, the last step in the glycolytic pathway
YML053C 2.03 Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and the nucleus; YML053C is not an essential gene
YGR264C 2.02
MES1
Methionyl-tRNA synthetase, forms a complex with glutamyl-tRNA synthetase (Gus1p) and Arc1p, which increases the catalytic efficiency of both tRNA synthetases; also has a role in nuclear export of tRNAs
YMR290W-A 2.01 Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data; overlaps 5' end of essential HAS1 gene which encodes an ATP-dependent RNA helicase
YJL107C 1.98 Putative protein of unknown function; expression is induced by activation of the HOG1 mitogen-activated signaling pathway and this induction is Hog1p/Pbs2p dependent; YJL107C and adjacent ORF, YJL108C are merged in related fungi
YDL047W 1.96
SIT4
Type 2A-related serine-threonine phosphatase that functions in the G1/S transition of the mitotic cycle; cytoplasmic and nuclear protein that modulates functions mediated by Pkc1p including cell wall and actin cytoskeleton organization
YMR183C 1.95
SSO2
Plasma membrane t-SNARE involved in fusion of secretory vesicles at the plasma membrane; syntaxin homolog that is functionally redundant with Sso1p
YLL008W 1.95
DRS1
Nucleolar DEAD-box protein required for ribosome assembly and function, including synthesis of 60S ribosomal subunits; constituent of 66S pre-ribosomal particles
YHR023W 1.92
MYO1
Type II myosin heavy chain, required for wild-type cytokinesis and cell separation; localizes to the actomyosin ring; binds to myosin light chains Mlc1p and Mlc2p through its IQ1 and IQ2 motifs respectively
YDR098C 1.85
GRX3
Hydroperoxide and superoxide-radical responsive glutathione-dependent oxidoreductase; monothiol glutaredoxin subfamily member along with Grx4p and Grx5p; protects cells from oxidative damage
YIL118W 1.84
RHO3
Non-essential small GTPase of the Rho/Rac subfamily of Ras-like proteins involved in the establishment of cell polarity; GTPase activity positively regulated by the GTPase activating protein (GAP) Rgd1p
YKL218C 1.82
SRY1
3-hydroxyaspartate dehydratase, deaminates L-threo-3-hydroxyaspartate to form oxaloacetate and ammonia; required for survival in the presence of hydroxyaspartate
YOL139C 1.82
CDC33
Cytoplasmic mRNA cap binding protein; the eIF4E-cap complex is responsible for mediating cap-dependent mRNA translation via interactions with the translation initiation factor eIF4G (Tif4631p or Tif4632p)
YPL250W-A 1.79 Identified by fungal homology and RT-PCR
YPR029C 1.76
APL4
Gamma-adaptin, large subunit of the clathrin-associated protein (AP-1) complex; binds clathrin; involved in vesicle mediated transport
YMR290C 1.74
HAS1
ATP-dependent RNA helicase; localizes to both the nuclear periphery and nucleolus; highly enriched in nuclear pore complex fractions; constituent of 66S pre-ribosomal particles
YDR146C 1.73
SWI5
Transcription factor that activates transcription of genes expressed at the M/G1 phase boundary and in G1 phase; localization to the nucleus occurs during G1 and appears to be regulated by phosphorylation by Cdc28p kinase
YLR150W 1.68
STM1
Protein that binds G4 quadruplex and purine motif triplex nucleic acid; acts with Cdc13p to maintain telomere structure; interacts with ribosomes and subtelomeric Y' DNA; multicopy suppressor of tom1 and pop2 mutations
YOL123W 1.64
HRP1
Subunit of cleavage factor I, a five-subunit complex required for the cleavage and polyadenylation of pre-mRNA 3' ends; RRM-containing heteronuclear RNA binding protein and hnRNPA/B family member that binds to poly (A) signal sequences
YOR226C 1.61
ISU2
Conserved protein of the mitochondrial matrix, required for synthesis of mitochondrial and cytosolic iron-sulfur proteins, performs a scaffolding function in mitochondria during Fe/S cluster assembly; isu1 isu2 double mutant is inviable
YPR119W 1.58
CLB2
B-type cyclin involved in cell cycle progression; activates Cdc28p to promote the transition from G2 to M phase; accumulates during G2 and M, then targeted via a destruction box motif for ubiquitin-mediated degradation by the proteasome
YPL037C 1.53
EGD1
Subunit beta1 of the nascent polypeptide-associated complex (NAC) involved in protein targeting, associated with cytoplasmic ribosomes; enhances DNA binding of the Gal4p activator; homolog of human BTF3b
YPR102C 1.51
RPL11A
Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl11Bp; involved in ribosomal assembly; depletion causes degradation of proteins and RNA of the 60S subunit; has similarity to E. coli L5 and rat L11
YFL016C 1.50
MDJ1
Co-chaperone that stimulates the ATPase activity of the HSP70 protein Ssc1p; involved in protein folding/refolding in the mitochodrial matrix; required for proteolysis of misfolded proteins; member of the HSP40 (DnaJ) family of chaperones
YML043C 1.49
RRN11
Protein required for rDNA transcription by RNA polymerase I, component of the core factor (CF) of rDNA transcription factor, which also contains Rrn6p and Rrn7p
YOR101W 1.47
RAS1
GTPase involved in G-protein signaling in the adenylate cyclase activating pathway, plays a role in cell proliferation; localized to the plasma membrane; homolog of mammalian RAS proto-oncogenes
YOL124C 1.47
TRM11
Catalytic subunit of an adoMet-dependent tRNA methyltransferase complex (Trm11p-Trm112p), required for the methylation of the guanosine nucleotide at position 10 (m2G10) in tRNAs; contains a THUMP domain and a methyltransferase domain
YJL106W 1.46
IME2
Serine/threonine protein kinase involved in activation of meiosis, associates with Ime1p and mediates its stability, activates Ndt80p; IME2 expression is positively regulated by Ime1p
YFL022C 1.45
FRS2
Alpha subunit of cytoplasmic phenylalanyl-tRNA synthetase, forms a tetramer with Frs1p to form active enzyme; evolutionarily distant from mitochondrial phenylalanyl-tRNA synthetase based on protein sequence, but substrate binding is similar
YGL097W 1.37
SRM1
Nucleotide exchange factor for Gsp1p, localizes to the nucleus, required for nucleocytoplasmic trafficking of macromolecules; suppressor of the pheromone response pathway; potentially phosphorylated by Cdc28p
YER146W 1.35
LSM5
Lsm (Like Sm) protein; part of heteroheptameric complexes (Lsm2p-7p and either Lsm1p or 8p): cytoplasmic Lsm1p complex involved in mRNA decay; nuclear Lsm8p complex part of U6 snRNP and possibly involved in processing tRNA, snoRNA, and rRNA
YNL118C 1.33
DCP2
Catalytic subunit of the Dcp1p-Dcp2p decapping enzyme complex, which removes the 5' cap structure from mRNAs prior to their degradation; member of the Nudix hydrolase family
YPR043W 1.30
RPL43A
Protein component of the large (60S) ribosomal subunit, identical to Rpl43Bp and has similarity to rat L37a ribosomal protein; null mutation confers a dominant lethal phenotype
YLR355C 1.29
ILV5
Acetohydroxyacid reductoisomerase, mitochondrial protein involved in branched-chain amino acid biosynthesis, also required for maintenance of wild-type mitochondrial DNA and found in mitochondrial nucleoids
YMR123W 1.27
PKR1
V-ATPase assembly factor, functions with other V-ATPase assembly factors in the ER to efficiently assemble the V-ATPase membrane sector (V0); overproduction confers resistance to Pichia farinosa killer toxin
YDR060W 1.26
MAK21
Constituent of 66S pre-ribosomal particles, required for large (60S) ribosomal subunit biogenesis; involved in nuclear export of pre-ribosomes; required for maintenance of dsRNA virus; homolog of human CAATT-binding protein
YOR157C 1.26
PUP1
Endopeptidase with trypsin-like activity that cleaves after basic residues; beta 2 subunit of 20S proteasome, synthesized as a proprotein before being proteolytically processed for assembly into 20S particle; human homolog is subunit Z
YBL085W 1.26
BOI1
Protein implicated in polar growth, functionally redundant with Boi2p; interacts with bud-emergence protein Bem1p; contains an SH3 (src homology 3) domain and a PH (pleckstrin homology) domain
YMR184W 1.24
ADD37
Protein of unknown function involved in ER-associated protein degradation; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and is induced in response to the DNA-damaging agent MMS; YMR184W is not an essential gene
YHL015W 1.20
RPS20
Protein component of the small (40S) ribosomal subunit; overproduction suppresses mutations affecting RNA polymerase III-dependent transcription; has similarity to E. coli S10 and rat S20 ribosomal proteins
YKR075C 1.18 Protein of unknown function; similar to YOR062Cp and Reg1p; expression regulated by glucose and Rgt1p; GFP-fusion protein is induced in response to the DNA-damaging agent MMS
YDR041W 1.15
RSM10
Mitochondrial ribosomal protein of the small subunit, has similarity to E. coli S10 ribosomal protein; essential for viability, unlike most other mitoribosomal proteins
YKL063C 1.14 Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the Golgi
YNL113W 1.13
RPC19
RNA polymerase subunit, common to RNA polymerases I and III
YPL075W 1.11
GCR1
Transcriptional activator of genes involved in glycolysis; DNA-binding protein that interacts and functions with the transcriptional activator Gcr2p
YOR318C 1.09 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; transcript is predicted to be spliced but there is no evidence that it is spliced in vivo
YOR047C 1.09
STD1
Protein involved in control of glucose-regulated gene expression; interacts with protein kinase Snf1p, glucose sensors Snf3p and Rgt2p, and TATA-binding protein Spt15p; acts as a regulator of the transcription factor Rgt1p
YIL053W 1.08
RHR2
Constitutively expressed isoform of DL-glycerol-3-phosphatase; involved in glycerol biosynthesis, induced in response to both anaerobic and, along with the Hor2p/Gpp2p isoform, osmotic stress
YFR051C 1.05
RET2
Delta subunit of the coatomer complex (COPI), which coats Golgi-derived transport vesicles; involved in retrograde transport between Golgi and ER
YKR094C 1.05
RPL40B
Fusion protein, identical to Rpl40Ap, that is cleaved to yield ubiquitin and a ribosomal protein of the large (60S) ribosomal subunit with similarity to rat L40; ubiquitin may facilitate assembly of the ribosomal protein into ribosomes
YDL048C 1.04
STP4
Protein containing a Kruppel-type zinc-finger domain; has similarity to Stp1p, Stp2p, and Stp3p
YDR040C 1.04
ENA1
P-type ATPase sodium pump, involved in Na+ and Li+ efflux to allow salt tolerance
YGR108W 1.03
CLB1
B-type cyclin involved in cell cycle progression; activates Cdc28p to promote the transition from G2 to M phase; accumulates during G2 and M, then targeted via a destruction box motif for ubiquitin-mediated degradation by the proteasome
YMR001C-A 1.02 Putative protein of unknown function
YGR145W 1.02
ENP2
Essential nucleolar protein of unknown function; contains WD repeats, interacts with Mpp10p and Bfr2p, and has homology to Spb1p
YEL053W-A 1.01 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified gene YEL054C
YKL110C 1.01
KTI12
Protein that plays a role, with Elongator complex, in modification of wobble nucleosides in tRNA; involved in sensitivity to G1 arrest induced by zymocin; interacts with chromatin throughout the genome; also interacts with Cdc19p
YLR333C 1.00
RPS25B
Protein component of the small (40S) ribosomal subunit; nearly identical to Rps25Ap and has similarity to rat S25 ribosomal protein
YBR049C 0.99
REB1
RNA polymerase I enhancer binding protein; DNA binding protein which binds to genes transcribed by both RNA polymerase I and RNA polymerase II; required for termination of RNA polymerase I transcription
YOR369C 0.98
RPS12
Protein component of the small (40S) ribosomal subunit; has similarity to rat ribosomal protein S12
YGR195W 0.97
SKI6
3'-to-5' phosphorolytic exoribonuclease that is a subunit of the exosome; required for 3' processing of the 5.8S rRNA; involved in 3' to 5' mRNA degradation and translation inhibition of non-poly(A) mRNAs
YBL077W 0.95 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified gene ILS1/YBL076C
YKL122C 0.94
SRP21
Subunit of the signal recognition particle (SRP), which functions in protein targeting to the endoplasmic reticulum membrane; not found in mammalian SRP; forms a pre-SRP structure in the nucleolus that is translocated to the cytoplasm
YJL200C 0.93
ACO2
Putative mitochondrial aconitase isozyme; similarity to Aco1p, an aconitase required for the TCA cycle; expression induced during growth on glucose, by amino acid starvation via Gcn4p, and repressed on ethanol
YOR299W 0.92
BUD7
Member of the ChAPs family of proteins (Chs5p-Arf1p-binding proteins: Bch1p, Bch2p, Bud7p, Chs6p), that forms the exomer complex with Chs5p to mediate export of specific cargo proteins, including Chs3p, from the Golgi to the plasma membrane
YDL085C-A 0.92 Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus
YNL065W 0.92
AQR1
Plasma membrane multidrug transporter of the major facilitator superfamily, confers resistance to short-chain monocarboxylic acids and quinidine; involved in the excretion of excess amino acids
YGR245C 0.92
SDA1
Highly conserved nuclear protein required for actin cytoskeleton organization and passage through Start, plays a critical role in G1 events, binds Nap1p, also involved in 60S ribosome biogenesis
YML121W 0.91
GTR1
Cytoplasmic GTP binding protein and negative regulator of the Ran/Tc4 GTPase cycle; component of GSE complex, which is required for sorting of Gap1p; involved in phosphate transport and telomeric silencing; similar to human RagA and RagB
YGL070C 0.91
RPB9
RNA polymerase II subunit B12.6; contacts DNA; mutations affect transcription start site; involved in telomere maintenance
YIL056W 0.88
VHR1
Transcriptional activator, required for the vitamin H-responsive element (VHRE) mediated induction of VHT1 (Vitamin H transporter) and BIO5 (biotin biosynthesis intermediate transporter) in response to low biotin concentrations
YLL021W 0.88
SPA2
Component of the polarisome, which functions in actin cytoskeletal organization during polarized growth; acts as a scaffold for Mkk1p and Mpk1p cell wall integrity signaling components; potential Cdc28p substrate
YLR196W 0.87
PWP1
Protein with WD-40 repeats involved in rRNA processing; associates with trans-acting ribosome biogenesis factors; similar to beta-transducin superfamily
YLR249W 0.87
YEF3
Translational elongation factor 3, stimulates the binding of aminoacyl-tRNA (AA-tRNA) to ribosomes by releasing EF-1 alpha from the ribosomal complex; contains two ABC cassettes; binds and hydrolyses ATP
YBR002C 0.87
RER2
Cis-prenyltransferase involved in dolichol synthesis; participates in endoplasmic reticulum (ER) protein sorting
YOL012C 0.87
HTZ1
Histone variant H2AZ, exchanged for histone H2A in nucleosomes by the SWR1 complex; involved in transcriptional regulation through prevention of the spread of silent heterochromatin
YMR016C 0.86
SOK2
Nuclear protein that plays a regulatory role in the cyclic AMP (cAMP)-dependent protein kinase (PKA) signal transduction pathway; negatively regulates pseudohyphal differentiation; homologous to several transcription factors
YER130C 0.86 Hypothetical protein
YNL111C 0.86
CYB5
Cytochrome b5, involved in the sterol and lipid biosynthesis pathways; acts as an electron donor to support sterol C5-6 desaturation
YIL148W 0.85
RPL40A
Fusion protein, identical to Rpl40Bp, that is cleaved to yield ubiquitin and a ribosomal protein of the large (60S) ribosomal subunit with similarity to rat L40; ubiquitin may facilitate assembly of the ribosomal protein into ribosomes
YPL055C 0.85
LGE1
Protein of unknown function; null mutant forms abnormally large cells, and homozygous diploid null mutant displays delayed premeiotic DNA synthesis and reduced efficiency of meiotic nuclear division
YFL014W 0.85
HSP12
Plasma membrane localized protein that protects membranes from desiccation; induced by heat shock, oxidative stress, osmostress, stationary phase entry, glucose depletion, oleate and alcohol; regulated by the HOG and Ras-Pka pathways
YOR025W 0.85
HST3
Member of the Sir2 family of NAD(+)-dependent protein deacetylases; involved along with Hst4p in telomeric silencing, cell cycle progression, radiation resistance, genomic stability and short-chain fatty acid metabolism
YER019C-A 0.85
SBH2
Ssh1p-Sss1p-Sbh2p complex component, involved in protein translocation into the endoplasmic reticulum; homologous to Sbh1p
YLR401C 0.84
DUS3
Dihydrouridine synthase, member of a widespread family of conserved proteins including Smm1p, Dus1p, and Dus4p; contains a consensus oleate response element (ORE) in its promoter region
YLR358C 0.84 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified ORF RSC2/YLR357W
YER156C 0.84 Putative protein of unknown function; identified as interacting with Hsp82p in a high-throughput two-hybrid screen; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus
YDL173W 0.84 Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; YDL173W is not an essential gene
YJL198W 0.83
PHO90
Low-affinity phosphate transporter; deletion of pho84, pho87, pho89, pho90, and pho91 causes synthetic lethality; transcription independent of Pi and Pho4p activity; overexpression results in vigorous growth
YOR046C 0.83
DBP5
Cytoplasmic ATP-dependent RNA helicase of the DEAD-box family involved in mRNA export from the nucleus; involved in translation termination
YLR254C 0.83
NDL1
Homolog of nuclear distribution factor NudE, NUDEL; interacts with Pac1p and regulates dynein targeting to microtubule plus ends
YJR076C 0.83
CDC11
Component of the septin ring of the mother-bud neck that is required for cytokinesis; septins recruit proteins to the neck and can act as a barrier to diffusion at the membrane, and they comprise the 10nm filaments seen with EM
YDR156W 0.83
RPA14
RNA polymerase I subunit A14
YDR144C 0.83
MKC7
GPI-anchored aspartyl protease (yapsin) involved in protein processing; shares functions with Yap3p and Kex2p
YDL031W 0.82
DBP10
Putative ATP-dependent RNA helicase of the DEAD-box protein family, constituent of 66S pre-ribosomal particles; essential protein involved in ribosome biogenesis
YBR017C 0.82
KAP104
Transportin, cytosolic karyopherin beta 2 involved in delivery of heterogeneous nuclear ribonucleoproteins to the nucleoplasm, binds rg-nuclear localization signals on Nab2p and Hrp1p, plays a role in cell-cycle progression
YHR127W 0.82 Protein of unknown function; localizes to the nucleus
YPL160W 0.82
CDC60
Cytosolic leucyl tRNA synthetase, ligates leucine to the appropriate tRNA
YIR012W 0.82
SQT1
Essential protein involved in a late step of 60S ribosomal subunit assembly or modification; contains multiple WD repeats; interacts with Qsr1p in a two-hybrid assay
YML119W 0.80 Putative protein of unknown funtion; YML119W is not an essential gene; potential Cdc28p substrate
YDR147W 0.80
EKI1
Ethanolamine kinase, primarily responsible for phosphatidylethanolamine synthesis via the CDP-ethanolamine pathway; exhibits some choline kinase activity, thus contributing to phosphatidylcholine synthesis via the CDP-choline pathway
YPL238C 0.80 Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data; partially overlaps 5' end of the verified essential gene SUI3/YPL237W
YJL194W 0.80
CDC6
Essential ATP-binding protein required for DNA replication, component of the pre-replicative complex (pre-RC) which requires ORC to associate with chromatin and is in turn required for Mcm2-7p DNA association; homologous to S. pombe Cdc18p
YDL148C 0.80
NOP14
Nucleolar protein, forms a complex with Noc4p that mediates maturation and nuclear export of 40S ribosomal subunits; also present in the small subunit processome complex, which is required for processing of pre-18S rRNA
YFR055W 0.79
IRC7
Putative cystathionine beta-lyase; involved in copper ion homeostasis and sulfur metabolism; null mutant displays increased levels of spontaneous Rad52p foci; expression induced by nitrogen limitation in a GLN3, GAT1-dependent manner
YOR271C 0.79
FSF1
Putative protein, predicted to be an alpha-isopropylmalate carrier; belongs to the sideroblastic-associated protein family; non-tagged protein is detected in purified mitochondria; likely to play a role in iron homeostasis
YGR280C 0.78
PXR1
Essential protein involved in rRNA and snoRNA maturation; competes with TLC1 RNA for binding to Est2p, suggesting a role in negative regulation of telomerase; human homolog inhibits telomerase; contains a G-patch RNA interacting domain
YLL012W 0.77
YEH1
Steryl ester hydrolase, one of three gene products (Yeh1p, Yeh2p, Tgl1p) responsible for steryl ester hydrolase activity and involved in sterol homeostasis; localized to lipid particle membranes
YAL025C 0.77
MAK16
Essential nuclear protein, constituent of 66S pre-ribosomal particles; required for maturation of 25S and 5.8S rRNAs; required for maintenance of M1 satellite double-stranded RNA of the L-A virus
YPL212C 0.77
PUS1
tRNA:pseudouridine synthase, introduces pseudouridines at positions 26-28, 34-36, 65, and 67 of tRNA; nuclear protein that appears to be involved in tRNA export; also acts on U2 snRNA
YKL118W 0.77 Dubious open reading frame, unlikely to encode a protein; partially overlaps the verified gene VPH2
YMR214W 0.76
SCJ1
One of several homologs of bacterial chaperone DnaJ, located in the ER lumen where it cooperates with Kar2p to mediate maturation of proteins
YPR163C 0.76
TIF3
Translation initiation factor eIF-4B, has RNA annealing activity; contains an RNA recognition motif and binds to single-stranded RNA
YOR073W-A 0.76 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially/completely overlaps the verified ORF CDC21/YOR074C; identified by RT-PCR
YOL085C 0.75 Dubious open reading frame unlikely to encode a protein, based on experimental and comparative sequence data; partially overlaps the dubious gene YOL085W-A
YNL301C 0.74
RPL18B
Protein component of the large (60S) ribosomal subunit, identical to Rpl18Ap and has similarity to rat L18 ribosomal protein
YER159C 0.74
BUR6
Subunit of a heterodimeric NC2 transcription regulator complex with Ncb2p; complex binds to TBP and can repress transcription by preventing preinitiation complex assembly or stimulate activated transcription; homologous to human NC2alpha
YMR121C 0.74
RPL15B
Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl15Ap and has similarity to rat L15 ribosomal protein; binds to 5.8 S rRNA
YKL182W 0.73
FAS1
Beta subunit of fatty acid synthetase, which catalyzes the synthesis of long-chain saturated fatty acids; contains acetyltransacylase, dehydratase, enoyl reductase, malonyl transacylase, and palmitoyl transacylase activities
YIL009W 0.73
FAA3
Long chain fatty acyl-CoA synthetase, has a preference for C16 and C18 fatty acids; green fluorescent protein (GFP)-fusion protein localizes to the cell periphery
YOR361C 0.72
PRT1
Subunit of the core complex of translation initiation factor 3(eIF3), essential for translation; part of a subcomplex (Prt1p-Rpg1p-Nip1p) that stimulates binding of mRNA and tRNA(i)Met to ribosomes
YDL213C 0.72
NOP6
Putative RNA-binding protein implicated in ribosome biogenesis; contains an RNA recognition motif (RRM) and has similarity to hydrophilins; NOP6 may be a fungal-specific gene as no homologs have been yet identified in higher eukaryotes
YGR078C 0.72
PAC10
Part of the heteromeric co-chaperone GimC/prefoldin complex, which promotes efficient protein folding
YLR406C 0.71
RPL31B
Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl31Ap and has similarity to rat L31 ribosomal protein; associates with the karyopherin Sxm1p
YKL072W 0.71
STB6
Protein that binds Sin3p in a two-hybrid assay
YHR148W 0.70
IMP3
Component of the SSU processome, which is required for pre-18S rRNA processing, essential protein that interacts with Mpp10p and mediates interactions of Imp4p and Mpp10p with U3 snoRNA
YDR299W 0.70
BFR2
Essential protein possibly involved in secretion; multicopy suppressor of sensitivity to Brefeldin A
YER064C 0.70 Non-essential nuclear protein; null mutation has global effects on transcription
YGL179C 0.69
TOS3
Protein kinase, related to and functionally redundant with Elm1p and Sak1p for the phosphorylation and activation of Snf1p; functionally orthologous to LKB1, a mammalian kinase associated with Peutz-Jeghers cancer-susceptibility syndrome
YJL115W 0.69
ASF1
Nucleosome assembly factor, involved in chromatin assembly and disassembly, anti-silencing protein that causes derepression of silent loci when overexpressed; plays a role in regulating Ty1 transposition
YOR287C 0.69 Putative protein of unknown function; may play a role in the ribosome and rRNA biosynthesis based on expression profiles and mutant phenotype
YDL192W 0.69
ARF1
ADP-ribosylation factor, GTPase of the Ras superfamily involved in regulation of coated vesicle formation in intracellular trafficking within the Golgi; functionally interchangeable with Arf2p
YBL032W 0.69
HEK2
RNA binding protein with similarity to hnRNP-K that localizes to the cytoplasm and to subtelomeric DNA; required for the proper localization of ASH1 mRNA; involved in the regulation of telomere position effect and telomere length
YDL208W 0.68
NHP2
Nuclear protein related to mammalian high mobility group (HMG) proteins, essential for function of H/ACA-type snoRNPs, which are involved in 18S rRNA processing
YER151C 0.68
UBP3
Ubiquitin-specific protease that interacts with Bre5p to co-regulate anterograde and retrograde transport between endoplasmic reticulum and Golgi compartments; inhibitor of gene silencing; cleaves ubiquitin fusions but not polyubiquitin
YKL119C 0.68
VPH2
Integral membrane protein required for vacuolar H+-ATPase (V-ATPase) function, although not an actual component of the V-ATPase complex; functions in the assembly of the V-ATPase; localized to the endoplasmic reticulum (ER)
YOR074C 0.68
CDC21
Thymidylate synthase, required for de novo biosynthesis of pyrimidine deoxyribonucleotides; expression is induced at G1/S
YBR034C 0.68
HMT1
Nuclear SAM-dependent mono- and asymmetric arginine dimethylating methyltransferase that modifies hnRNPs, including Npl3p and Hrp1p, thus facilitating nuclear export of these proteins; required for viability of npl3 mutants
YOR276W 0.68
CAF20
Phosphoprotein of the mRNA cap-binding complex involved in translational control, repressor of cap-dependent translation initiation, competes with eIF4G for binding to eIF4E
YNL079C 0.67
TPM1
Major isoform of tropomyosin; binds to and stabilizes actin cables and filaments, which direct polarized cell growth and the distribution of several organelles; acetylated by the NatB complex and acetylated form binds actin most efficiently
YHR203C 0.67
RPS4B
Protein component of the small (40S) ribosomal subunit; identical to Rps4Ap and has similarity to rat S4 ribosomal protein
YMR015C 0.67
ERG5
C-22 sterol desaturase, a cytochrome P450 enzyme that catalyzes the formation of the C-22(23) double bond in the sterol side chain in ergosterol biosynthesis; may be a target of azole antifungal drugs
YHR146W 0.67
CRP1
Protein that binds to cruciform DNA structures
YDL226C 0.67
GCS1
ADP-ribosylation factor GTPase activating protein (ARF GAP), involved in ER-Golgi transport; shares functional similarity with Glo3p
YDR086C 0.67
SSS1
Subunit of the Sec61p translocation complex (Sec61p-Sss1p-Sbh1p) that forms a channel for passage of secretory proteins through the endoplasmic reticulum membrane, and of the Ssh1p complex (Ssh1p-Sbh2p-Sss1p); interacts with Ost4p and Wbp1p
YBR257W 0.66
POP4
Subunit of both RNase MRP, which cleaves pre-rRNA, and nuclear RNase P, which cleaves tRNA precursors to generate mature 5' ends; binds to the RPR1 RNA subunit in Rnase P
YJL076W 0.66
NET1
Core subunit of the RENT complex, which is a complex involved in nucleolar silencing and telophase exit; stimulates transcription by RNA polymerase I and regulates nucleolar structure
YOR063W 0.66
RPL3
Protein component of the large (60S) ribosomal subunit, has similarity to E. coli L3 and rat L3 ribosomal proteins; involved in the replication and maintenance of killer double stranded RNA virus
YIL117C 0.65
PRM5
Pheromone-regulated protein, predicted to have 1 transmembrane segment; induced during cell integrity signaling
YMR091C 0.65
NPL6
Component of the RSC chromatin remodeling complex; interacts with Rsc3p, Rsc30p, Ldb7p, and Htl1p to form a module important for a broad range of RSC functions; involved in nuclear protein import and maintenance of proper telomere length
YGR079W 0.65 Putative protein of unknown function; YGR079W is not an essential gene
YBR171W 0.65
SEC66
Non-essential subunit of Sec63 complex (Sec63p, Sec62p, Sec66p and Sec72p); with Sec61 complex, Kar2p/BiP and Lhs1p forms a channel competent for SRP-dependent and post-translational SRP-independent protein targeting and import into the ER
YPR142C 0.65 Hypothetical protein; open reading frame overlaps 5' end of essential RRP15 gene required for ribosomal RNA processing
YCR051W 0.65 Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus; contains ankyrin (Ank) repeats; YCR051W is not an essential gene
YOR198C 0.65
BFR1
Component of mRNP complexes associated with polyribosomes; implicated in secretion and nuclear segregation; multicopy suppressor of BFA (Brefeldin A) sensitivity
YFR056C 0.65 Dubious open reading frame unlikely to encode a protein based on available experimental and comparative sequence data; partially overlaps the uncharacterized gene YFR055W
YPR157W 0.65 Putative protein of unknown function; induced by treatment with 8-methoxypsoralen and UVA irradiation
YGR285C 0.65
ZUO1
Cytosolic ribosome-associated chaperone that acts, together with Ssz1p and the Ssb proteins, as a chaperone for nascent polypeptide chains; contains a DnaJ domain and functions as a J-protein partner for Ssb1p and Ssb2p
YDR412W 0.64
RRP17
Component of the pre-60S pre-ribosomal particle; required for cell viability
YJR092W 0.64
BUD4
Protein involved in bud-site selection and required for axial budding pattern; localizes with septins to bud neck in mitosis and may constitute an axial landmark for next round of budding; potential Cdc28p substrate
YDR101C 0.64
ARX1
Shuttling pre-60S factor; involved in the biogenesis of ribosomal large subunit biogenesis; interacts directly with Alb1; responsible for Tif6 recycling defects in absence of Rei1; associated with the ribosomal export complex
YGL120C 0.64
PRP43
RNA helicase in the DEAH-box family, functions in both RNA polymerase I and polymerase II transcript metabolism, involved in release of the lariat-intron from the spliceosome
YKR035W-A 0.64
DID2
Class E protein of the vacuolar protein-sorting (Vps) pathway; binds Vps4p and directs it to dissociate ESCRT-III complexes; forms a functional and physical complex with Ist1p; human ortholog may be altered in breast tumors
YJR003C 0.64 Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies
YOL038W 0.63
PRE6
Alpha 4 subunit of the 20S proteasome; may replace alpha 3 subunit (Pre9p) under stress conditions to create a more active proteasomal isoform; GFP-fusion protein relocates from cytosol to the mitochondrial surface upon oxidative stress
YGL177W 0.63 Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data
YML001W 0.63
YPT7
GTPase; GTP-binding protein of the rab family; required for homotypic fusion event in vacuole inheritance, for endosome-endosome fusion, similar to mammalian Rab7
YNL216W 0.63
RAP1
DNA-binding protein involved in either activation or repression of transcription, depending on binding site context; also binds telomere sequences and plays a role in telomeric position effect (silencing) and telomere structure
YLR206W 0.63
ENT2
Epsin-like protein required for endocytosis and actin patch assembly and functionally redundant with Ent1p; contains clathrin-binding motif at C-terminus
YDR207C 0.63
UME6
Key transcriptional regulator of early meiotic genes, binds URS1 upstream regulatory sequence, couples metabolic responses to nutritional cues with initiation and progression of meiosis, forms complex with Ime1p, and also with Sin3p-Rpd3p
YGR060W 0.63
ERG25
C-4 methyl sterol oxidase, catalyzes the first of three steps required to remove two C-4 methyl groups from an intermediate in ergosterol biosynthesis; mutants accumulate the sterol intermediate 4,4-dimethylzymosterol
YGR052W 0.63
FMP48
Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; induced by treatment with 8-methoxypsoralen and UVA irradiation
YOR319W 0.62
HSH49
U2-snRNP associated splicing factor with similarity to the mammalian splicing factor SAP49; proposed to function as a U2-snRNP assembly factor along with Hsh155p and binding partner Cus1p; contains two RNA recognition motifs (RRM)
YFR037C 0.62
RSC8
Component of the RSC chromatin remodeling complex; essential for viability and mitotic growth; homolog of SWI/SNF subunit Swi3p, but unlike Swi3p, does not activate transcription of reporters
YMR106C 0.62
YKU80
Subunit of the telomeric Ku complex (Yku70p-Yku80p), involved in telomere length maintenance, structure and telomere position effect; relocates to sites of double-strand cleavage to promote nonhomologous end joining during DSB repair
YGL148W 0.62
ARO2
Bifunctional chorismate synthase and flavin reductase, catalyzes the conversion of 5-enolpyruvylshikimate 3-phosphate (EPSP) to form chorismate, which is a precursor to aromatic amino acids
YBR143C 0.62
SUP45
Polypeptide release factor involved in translation termination; mutant form acts as a recessive omnipotent suppressor
YDR450W 0.62
RPS18A
Protein component of the small (40S) ribosomal subunit; nearly identical to Rps18Bp and has similarity to E. coli S13 and rat S18 ribosomal proteins
YGR051C 0.62 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; YGR051C is not an essential gene
YPL237W 0.61
SUI3
Beta subunit of the translation initiation factor eIF2, involved in the identification of the start codon; proposed to be involved in mRNA binding
YOL031C 0.61
SIL1
Nucleotide exchange factor for the endoplasmic reticulum (ER) lumenal Hsp70 chaperone Kar2p, required for protein translocation into the ER; homolog of Yarrowia lipolytica SLS1; GrpE-like protein
YPR051W 0.61
MAK3
Catalytic subunit of N-terminal acetyltransferase of the NatC type; required for replication of dsRNA virus
YBR130C 0.60
SHE3
Protein that acts as an adaptor between Myo4p and the She2p-mRNA complex; part of the mRNA localization machinery that restricts accumulation of certain proteins to the bud; also required for cortical ER inheritance
YJL105W 0.60
SET4
Protein of unknown function, contains a SET domain
YML082W 0.60 Putative protein predicted to have carbon-sulfur lyase activity; green fluorescent protein (GFP)-fusion protein localizes to the nucleus and the cytoplasm; YNML082W is not an essential gene
YLR033W 0.60
RSC58
Component of the RSC chromatin remodeling complex; RSC functions in transcriptional regulation and elongation, chromosome stability, and establishing sister chromatid cohesion; involved in telomere maintenance58KDa subunit

Network of associatons between targets according to the STRING database.

First level regulatory network of REB1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.0 GO:0072361 regulation of glycolytic process by regulation of transcription from RNA polymerase II promoter(GO:0072361) regulation of glycolytic process by positive regulation of transcription from RNA polymerase II promoter(GO:0072363)
0.6 5.4 GO:0006814 sodium ion transport(GO:0006814)
0.6 1.7 GO:0007189 adenylate cyclase-activating G-protein coupled receptor signaling pathway(GO:0007189)
0.6 2.8 GO:0000912 assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin structure organization(GO:0031032) actomyosin contractile ring organization(GO:0044837)
0.5 2.0 GO:0070072 proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.5 1.5 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.5 1.4 GO:0060548 negative regulation of apoptotic process(GO:0043066) negative regulation of programmed cell death(GO:0043069) negative regulation of cell death(GO:0060548)
0.5 1.9 GO:0048313 Golgi inheritance(GO:0048313)
0.5 2.3 GO:0006363 termination of RNA polymerase I transcription(GO:0006363)
0.5 3.2 GO:0043457 regulation of cellular respiration(GO:0043457)
0.5 2.7 GO:0045896 regulation of transcription during mitosis(GO:0045896)
0.4 3.1 GO:0010696 positive regulation of spindle pole body separation(GO:0010696)
0.4 0.4 GO:0001178 regulation of transcriptional start site selection at RNA polymerase II promoter(GO:0001178)
0.4 1.3 GO:0006114 glycerol biosynthetic process(GO:0006114) alditol biosynthetic process(GO:0019401)
0.4 2.1 GO:0070649 parallel actin filament bundle assembly(GO:0030046) formin-nucleated actin cable assembly(GO:0070649)
0.4 1.7 GO:0006361 transcription initiation from RNA polymerase I promoter(GO:0006361)
0.4 2.9 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
0.4 2.0 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.4 1.2 GO:0009177 deoxyribonucleoside monophosphate biosynthetic process(GO:0009157) deoxyribonucleoside monophosphate metabolic process(GO:0009162) pyrimidine deoxyribonucleoside monophosphate metabolic process(GO:0009176) pyrimidine deoxyribonucleoside monophosphate biosynthetic process(GO:0009177)
0.4 1.1 GO:0070637 nicotinamide riboside metabolic process(GO:0046495) pyridine nucleoside metabolic process(GO:0070637)
0.4 1.1 GO:0031384 regulation of initiation of mating projection growth(GO:0031384)
0.3 1.0 GO:0002188 translation reinitiation(GO:0002188)
0.3 0.3 GO:0035337 fatty-acyl-CoA metabolic process(GO:0035337)
0.3 1.0 GO:0032006 regulation of TOR signaling(GO:0032006)
0.3 1.0 GO:0030037 actin filament reorganization involved in cell cycle(GO:0030037) actin filament reorganization(GO:0090527)
0.3 1.6 GO:0045947 negative regulation of translational initiation(GO:0045947)
0.3 1.2 GO:0031118 rRNA pseudouridine synthesis(GO:0031118)
0.3 1.5 GO:0051083 'de novo' cotranslational protein folding(GO:0051083)
0.3 1.5 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.3 1.2 GO:0071216 cellular response to biotic stimulus(GO:0071216) response to cell cycle checkpoint signaling(GO:0072396) response to mitotic cell cycle checkpoint signaling(GO:0072414) response to spindle checkpoint signaling(GO:0072417) response to mitotic spindle checkpoint signaling(GO:0072476) response to mitotic cell cycle spindle assembly checkpoint signaling(GO:0072479) response to spindle assembly checkpoint signaling(GO:0072485) negative regulation of protein import into nucleus during spindle assembly checkpoint(GO:1901925)
0.3 0.9 GO:0016093 polyprenol metabolic process(GO:0016093) polyprenol biosynthetic process(GO:0016094) dolichol metabolic process(GO:0019348) dolichol biosynthetic process(GO:0019408)
0.3 0.6 GO:0061422 positive regulation of transcription from RNA polymerase II promoter in response to alkaline pH(GO:0061422)
0.3 0.5 GO:0071044 histone mRNA metabolic process(GO:0008334) histone mRNA catabolic process(GO:0071044)
0.3 1.1 GO:0046898 response to organic cyclic compound(GO:0014070) response to cycloheximide(GO:0046898)
0.3 0.8 GO:0031120 snRNA pseudouridine synthesis(GO:0031120) snRNA modification(GO:0040031)
0.2 0.7 GO:0042780 tRNA 3'-end processing(GO:0042780)
0.2 1.0 GO:0034473 U1 snRNA 3'-end processing(GO:0034473)
0.2 0.2 GO:2000879 regulation of oligopeptide transport by regulation of transcription from RNA polymerase II promoter(GO:0035950) negative regulation of oligopeptide transport by negative regulation of transcription from RNA polymerase II promoter(GO:0035952) regulation of dipeptide transport by regulation of transcription from RNA polymerase II promoter(GO:0035953) negative regulation of dipeptide transport by negative regulation of transcription from RNA polymerase II promoter(GO:0035955) negative regulation of oligopeptide transport(GO:2000877) negative regulation of dipeptide transport(GO:2000879)
0.2 4.3 GO:0051029 rRNA export from nucleus(GO:0006407) rRNA transport(GO:0051029)
0.2 0.7 GO:0042126 nitrate metabolic process(GO:0042126) nitrate assimilation(GO:0042128)
0.2 7.8 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.2 0.5 GO:0006657 CDP-choline pathway(GO:0006657)
0.2 3.3 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.2 0.4 GO:0030837 negative regulation of actin filament polymerization(GO:0030837)
0.2 0.7 GO:0001676 long-chain fatty acid metabolic process(GO:0001676)
0.2 0.2 GO:0032186 cellular bud neck septin ring organization(GO:0032186)
0.2 3.0 GO:0006415 translational termination(GO:0006415)
0.2 1.3 GO:0009099 valine biosynthetic process(GO:0009099)
0.2 0.8 GO:0002943 tRNA dihydrouridine synthesis(GO:0002943)
0.2 0.4 GO:0031507 heterochromatin assembly(GO:0031507)
0.2 0.4 GO:0009202 deoxyribonucleoside triphosphate biosynthetic process(GO:0009202)
0.2 0.2 GO:0070827 chromatin maintenance(GO:0070827)
0.2 5.3 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.2 1.2 GO:0043242 negative regulation of protein complex disassembly(GO:0043242)
0.2 1.0 GO:0032845 negative regulation of telomere maintenance(GO:0032205) negative regulation of homeostatic process(GO:0032845)
0.2 0.6 GO:0043171 peptide catabolic process(GO:0043171)
0.2 0.6 GO:0001015 snoRNA transcription from an RNA polymerase II promoter(GO:0001015)
0.2 0.8 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.2 4.6 GO:0002097 tRNA wobble base modification(GO:0002097) tRNA wobble uridine modification(GO:0002098)
0.2 2.4 GO:0017148 negative regulation of translation(GO:0017148)
0.2 0.7 GO:0006658 phosphatidylserine metabolic process(GO:0006658)
0.2 2.9 GO:0006450 regulation of translational fidelity(GO:0006450)
0.2 1.1 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.2 0.7 GO:0009240 isopentenyl diphosphate biosynthetic process(GO:0009240) isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287) isopentenyl diphosphate metabolic process(GO:0046490)
0.2 0.9 GO:0000390 spliceosomal complex disassembly(GO:0000390)
0.2 3.7 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
0.2 0.9 GO:0070481 nuclear-transcribed mRNA catabolic process, non-stop decay(GO:0070481)
0.2 0.9 GO:0006279 premeiotic DNA replication(GO:0006279)
0.2 0.3 GO:0030042 actin filament depolymerization(GO:0030042)
0.2 3.0 GO:0031498 nucleosome disassembly(GO:0006337) chromatin disassembly(GO:0031498) protein-DNA complex disassembly(GO:0032986)
0.2 0.6 GO:0097271 protein localization to bud neck(GO:0097271)
0.2 2.1 GO:0042790 transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:0042790)
0.2 1.1 GO:0000743 nuclear migration involved in conjugation with cellular fusion(GO:0000743)
0.2 0.3 GO:0042992 negative regulation of transcription factor import into nucleus(GO:0042992)
0.2 0.8 GO:0043619 regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0043619)
0.2 0.6 GO:0007535 donor selection(GO:0007535)
0.2 0.6 GO:0009423 chorismate biosynthetic process(GO:0009423)
0.2 0.5 GO:0019419 sulfate assimilation, phosphoadenylyl sulfate reduction by phosphoadenylyl-sulfate reductase (thioredoxin)(GO:0019379) sulfate reduction(GO:0019419)
0.2 0.6 GO:0010511 regulation of phosphatidylinositol biosynthetic process(GO:0010511)
0.2 0.6 GO:0006616 SRP-dependent cotranslational protein targeting to membrane, translocation(GO:0006616)
0.2 0.9 GO:0007089 traversing start control point of mitotic cell cycle(GO:0007089)
0.1 0.7 GO:0046459 short-chain fatty acid metabolic process(GO:0046459)
0.1 4.6 GO:0098876 Golgi to plasma membrane transport(GO:0006893) vesicle-mediated transport to the plasma membrane(GO:0098876)
0.1 1.0 GO:0042991 transcription factor import into nucleus(GO:0042991)
0.1 1.6 GO:0045860 positive regulation of protein kinase activity(GO:0045860)
0.1 1.3 GO:0031204 posttranslational protein targeting to membrane, translocation(GO:0031204)
0.1 1.4 GO:0007021 tubulin complex assembly(GO:0007021)
0.1 0.6 GO:0015909 long-chain fatty acid transport(GO:0015909)
0.1 1.3 GO:0006474 N-terminal protein amino acid acetylation(GO:0006474)
0.1 0.4 GO:0034517 ribophagy(GO:0034517)
0.1 0.4 GO:0042148 strand invasion(GO:0042148)
0.1 0.4 GO:0032204 regulation of telomere maintenance(GO:0032204) regulation of telomere maintenance via telomerase(GO:0032210) regulation of telomere maintenance via telomere lengthening(GO:1904356) regulation of DNA biosynthetic process(GO:2000278)
0.1 0.5 GO:0015883 FAD transport(GO:0015883)
0.1 0.4 GO:0000492 box C/D snoRNP assembly(GO:0000492)
0.1 0.8 GO:0043489 RNA stabilization(GO:0043489) mRNA stabilization(GO:0048255)
0.1 0.4 GO:2000001 regulation of cell cycle checkpoint(GO:1901976) negative regulation of cell cycle checkpoint(GO:1901977) regulation of DNA damage checkpoint(GO:2000001) negative regulation of DNA damage checkpoint(GO:2000002) negative regulation of response to DNA damage stimulus(GO:2001021)
0.1 0.3 GO:0008105 asymmetric protein localization(GO:0008105)
0.1 0.4 GO:0070475 rRNA base methylation(GO:0070475)
0.1 0.8 GO:0051017 actin filament bundle assembly(GO:0051017) actin filament bundle organization(GO:0061572)
0.1 0.1 GO:0016584 nucleosome positioning(GO:0016584)
0.1 0.3 GO:0043270 positive regulation of ion transport(GO:0043270)
0.1 0.7 GO:0048309 endoplasmic reticulum inheritance(GO:0048309)
0.1 13.6 GO:0002181 cytoplasmic translation(GO:0002181)
0.1 2.0 GO:0030488 tRNA methylation(GO:0030488)
0.1 0.2 GO:0009186 deoxyribonucleoside diphosphate metabolic process(GO:0009186)
0.1 1.2 GO:0000947 amino acid catabolic process to alcohol via Ehrlich pathway(GO:0000947)
0.1 0.4 GO:0051436 negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle(GO:0051436) regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle(GO:0051439) negative regulation of ubiquitin protein ligase activity(GO:1904667)
0.1 3.0 GO:0006418 tRNA aminoacylation for protein translation(GO:0006418)
0.1 0.1 GO:0000973 posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973)
0.1 0.6 GO:0090435 protein targeting to nuclear inner membrane(GO:0036228) protein localization to nuclear envelope(GO:0090435)
0.1 1.2 GO:0007109 obsolete cytokinesis, completion of separation(GO:0007109)
0.1 1.1 GO:0006283 transcription-coupled nucleotide-excision repair(GO:0006283)
0.1 0.8 GO:0007000 nucleolus organization(GO:0007000)
0.1 16.6 GO:0006364 rRNA processing(GO:0006364)
0.1 0.7 GO:0031134 sister chromatid biorientation(GO:0031134)
0.1 1.5 GO:0040023 nuclear migration(GO:0007097) establishment of nucleus localization(GO:0040023) nucleus localization(GO:0051647)
0.1 1.6 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.1 1.0 GO:0006613 cotranslational protein targeting to membrane(GO:0006613) SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.1 0.8 GO:0006855 drug transmembrane transport(GO:0006855)
0.1 2.1 GO:0000055 ribosomal large subunit export from nucleus(GO:0000055)
0.1 0.9 GO:0032042 mitochondrial DNA metabolic process(GO:0032042)
0.1 0.3 GO:0006567 threonine catabolic process(GO:0006567)
0.1 0.5 GO:0009071 serine family amino acid catabolic process(GO:0009071)
0.1 1.1 GO:0031110 regulation of microtubule polymerization or depolymerization(GO:0031110)
0.1 0.3 GO:0044818 mitotic G2/M transition checkpoint(GO:0044818)
0.1 2.3 GO:0006360 transcription from RNA polymerase I promoter(GO:0006360)
0.1 1.1 GO:0090662 energy coupled proton transmembrane transport, against electrochemical gradient(GO:0015988) ATP hydrolysis coupled proton transport(GO:0015991) ATP hydrolysis coupled transmembrane transport(GO:0090662)
0.1 0.4 GO:0006458 'de novo' protein folding(GO:0006458)
0.1 0.3 GO:0034661 rRNA catabolic process(GO:0016075) ncRNA catabolic process(GO:0034661)
0.1 0.1 GO:0034063 stress granule assembly(GO:0034063)
0.1 0.2 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.1 0.4 GO:0017183 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.1 0.1 GO:0018202 peptidyl-histidine modification(GO:0018202)
0.1 0.4 GO:0000296 spermine transport(GO:0000296)
0.1 0.8 GO:0042219 cellular modified amino acid catabolic process(GO:0042219)
0.1 0.3 GO:0009106 lipoate metabolic process(GO:0009106) lipoate biosynthetic process(GO:0009107) protein lipoylation(GO:0009249)
0.1 0.5 GO:0031081 nuclear pore distribution(GO:0031081) nuclear pore localization(GO:0051664)
0.1 0.3 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.1 0.4 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.1 0.5 GO:0034724 DNA replication-independent nucleosome organization(GO:0034724)
0.1 0.4 GO:0017062 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551)
0.1 0.2 GO:0061412 positive regulation of transcription from RNA polymerase II promoter in response to amino acid starvation(GO:0061412)
0.1 0.8 GO:0032508 DNA duplex unwinding(GO:0032508)
0.1 1.4 GO:0007020 microtubule nucleation(GO:0007020) microtubule polymerization(GO:0046785)
0.1 0.7 GO:0006379 mRNA cleavage(GO:0006379)
0.1 0.6 GO:0045014 negative regulation of transcription from RNA polymerase II promoter by glucose(GO:0000433) negative regulation of transcription by glucose(GO:0045014)
0.1 1.2 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.1 0.2 GO:0051131 chaperone-mediated protein complex assembly(GO:0051131)
0.1 0.2 GO:0016578 histone deubiquitination(GO:0016578)
0.1 0.2 GO:0006110 regulation of glycolytic process(GO:0006110)
0.1 0.2 GO:0019673 GDP-mannose biosynthetic process(GO:0009298) GDP-mannose metabolic process(GO:0019673)
0.1 0.3 GO:0060277 obsolete negative regulation of transcription involved in G1 phase of mitotic cell cycle(GO:0060277)
0.1 0.1 GO:0010971 positive regulation of G2/M transition of mitotic cell cycle(GO:0010971) positive regulation of cell cycle G2/M phase transition(GO:1902751)
0.1 0.4 GO:0042274 ribosomal small subunit biogenesis(GO:0042274)
0.1 0.2 GO:0030497 fatty acid elongation(GO:0030497)
0.1 0.3 GO:0019218 regulation of steroid metabolic process(GO:0019218) regulation of ergosterol biosynthetic process(GO:0032443) regulation of steroid biosynthetic process(GO:0050810)
0.1 0.1 GO:1903726 negative regulation of phospholipid biosynthetic process(GO:0071072) negative regulation of phospholipid metabolic process(GO:1903726)
0.1 0.5 GO:0051452 vacuolar acidification(GO:0007035) pH reduction(GO:0045851) intracellular pH reduction(GO:0051452)
0.1 0.7 GO:0016973 poly(A)+ mRNA export from nucleus(GO:0016973)
0.1 0.6 GO:0007155 cell adhesion(GO:0007155) biological adhesion(GO:0022610)
0.1 2.5 GO:0006892 post-Golgi vesicle-mediated transport(GO:0006892)
0.1 0.2 GO:0031990 mRNA export from nucleus in response to heat stress(GO:0031990)
0.1 0.2 GO:0006529 asparagine biosynthetic process(GO:0006529)
0.1 0.3 GO:0000715 nucleotide-excision repair, DNA damage recognition(GO:0000715)
0.1 0.4 GO:1903338 regulation of cell wall organization or biogenesis(GO:1903338)
0.1 0.2 GO:0018065 protein-cofactor linkage(GO:0018065)
0.1 0.2 GO:0044070 regulation of anion transport(GO:0044070)
0.1 0.1 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.1 0.8 GO:0044396 actin cortical patch assembly(GO:0000147) actin cortical patch organization(GO:0044396)
0.1 0.9 GO:0006267 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
0.1 0.2 GO:0032012 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.1 0.2 GO:0045292 mRNA cis splicing, via spliceosome(GO:0045292)
0.1 0.7 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.1 1.5 GO:0016126 steroid biosynthetic process(GO:0006694) sterol biosynthetic process(GO:0016126)
0.1 1.1 GO:0007096 regulation of exit from mitosis(GO:0007096)
0.1 0.2 GO:0015809 arginine transport(GO:0015809)
0.1 0.2 GO:0006032 aminoglycan catabolic process(GO:0006026) chitin catabolic process(GO:0006032) amino sugar catabolic process(GO:0046348) glucosamine-containing compound catabolic process(GO:1901072)
0.1 0.4 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.1 0.2 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.1 0.3 GO:0010833 RNA-dependent DNA biosynthetic process(GO:0006278) telomere maintenance via telomerase(GO:0007004) telomere maintenance via telomere lengthening(GO:0010833)
0.0 0.3 GO:0046777 protein autophosphorylation(GO:0046777)
0.0 0.2 GO:0043328 protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328)
0.0 0.1 GO:0031382 mating projection assembly(GO:0031382)
0.0 1.6 GO:0006413 translational initiation(GO:0006413)
0.0 0.4 GO:0070816 phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.0 0.1 GO:0009262 deoxyribonucleotide metabolic process(GO:0009262) deoxyribonucleotide biosynthetic process(GO:0009263)
0.0 0.3 GO:0070096 mitochondrial outer membrane translocase complex assembly(GO:0070096)
0.0 0.3 GO:0030026 cellular manganese ion homeostasis(GO:0030026) manganese ion homeostasis(GO:0055071)
0.0 0.1 GO:0048211 Golgi vesicle budding(GO:0048194) Golgi vesicle docking(GO:0048211)
0.0 0.3 GO:0031570 DNA integrity checkpoint(GO:0031570)
0.0 0.1 GO:0000076 DNA replication checkpoint(GO:0000076)
0.0 0.3 GO:0042273 ribosomal large subunit biogenesis(GO:0042273)
0.0 0.0 GO:0031590 wybutosine metabolic process(GO:0031590) wybutosine biosynthetic process(GO:0031591)
0.0 0.0 GO:1902749 regulation of G2/M transition of mitotic cell cycle(GO:0010389) regulation of cell cycle G2/M phase transition(GO:1902749)
0.0 0.1 GO:0030308 negative regulation of cell growth(GO:0030308) negative regulation of pseudohyphal growth(GO:2000221)
0.0 1.1 GO:0032200 telomere maintenance(GO:0000723) telomere organization(GO:0032200) anatomical structure homeostasis(GO:0060249)
0.0 1.7 GO:0007346 regulation of mitotic cell cycle(GO:0007346)
0.0 0.3 GO:0000349 generation of catalytic spliceosome for first transesterification step(GO:0000349)
0.0 1.3 GO:0051123 RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123)
0.0 0.4 GO:0006284 base-excision repair(GO:0006284)
0.0 0.0 GO:0033567 defense response(GO:0006952) DNA replication, Okazaki fragment processing(GO:0033567)
0.0 0.1 GO:0046039 GTP biosynthetic process(GO:0006183) GTP metabolic process(GO:0046039)
0.0 0.2 GO:0070676 intralumenal vesicle formation(GO:0070676)
0.0 0.4 GO:0016125 steroid metabolic process(GO:0008202) sterol metabolic process(GO:0016125)
0.0 0.1 GO:0070932 histone H3 deacetylation(GO:0070932) histone H4 deacetylation(GO:0070933)
0.0 0.4 GO:0006334 nucleosome assembly(GO:0006334)
0.0 0.1 GO:0000022 mitotic spindle elongation(GO:0000022) spindle elongation(GO:0051231)
0.0 0.1 GO:0071825 lipid tube assembly(GO:0060988) protein-lipid complex assembly(GO:0065005) protein-lipid complex subunit organization(GO:0071825)
0.0 0.1 GO:0006048 UDP-N-acetylglucosamine metabolic process(GO:0006047) UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.0 0.4 GO:0006633 fatty acid biosynthetic process(GO:0006633)
0.0 0.1 GO:0016073 snRNA metabolic process(GO:0016073)
0.0 0.4 GO:0009267 cellular response to starvation(GO:0009267)
0.0 0.1 GO:0000730 meiotic DNA recombinase assembly(GO:0000707) DNA recombinase assembly(GO:0000730)
0.0 0.2 GO:0034314 Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.0 0.1 GO:0015780 nucleotide-sugar transport(GO:0015780)
0.0 0.2 GO:0048278 vesicle docking(GO:0048278)
0.0 0.3 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.0 0.2 GO:0006038 cell wall chitin biosynthetic process(GO:0006038) fungal-type cell wall chitin biosynthetic process(GO:0034221) fungal-type cell wall polysaccharide biosynthetic process(GO:0051278) cell wall polysaccharide biosynthetic process(GO:0070592) fungal-type cell wall polysaccharide metabolic process(GO:0071966)
0.0 0.2 GO:0045047 protein targeting to ER(GO:0045047)
0.0 0.2 GO:0010526 negative regulation of transposition, RNA-mediated(GO:0010526) negative regulation of transposition(GO:0010529)
0.0 0.1 GO:0035376 sterol import(GO:0035376)
0.0 0.6 GO:1902408 cellular bud site selection(GO:0000282) cytokinesis, site selection(GO:0007105) mitotic cytokinesis, site selection(GO:1902408)
0.0 0.1 GO:0043007 maintenance of rDNA(GO:0043007)
0.0 0.2 GO:0019722 calcium-mediated signaling(GO:0019722)
0.0 0.5 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.0 0.1 GO:1900101 regulation of endoplasmic reticulum unfolded protein response(GO:1900101)
0.0 0.2 GO:0007076 mitotic chromosome condensation(GO:0007076)
0.0 0.4 GO:0023058 adaptation of signaling pathway by response to pheromone involved in conjugation with cellular fusion(GO:0000754) adaptation of signaling pathway(GO:0023058)
0.0 0.1 GO:0090294 nitrogen catabolite activation of transcription from RNA polymerase II promoter(GO:0001080) nitrogen catabolite activation of transcription(GO:0090294)
0.0 0.2 GO:0015918 sterol transport(GO:0015918)
0.0 0.1 GO:0006673 inositolphosphoceramide metabolic process(GO:0006673)
0.0 0.1 GO:0051666 actin cortical patch localization(GO:0051666)
0.0 0.0 GO:0051292 pore complex assembly(GO:0046931) nuclear pore complex assembly(GO:0051292)
0.0 0.1 GO:0006998 nuclear envelope organization(GO:0006998)
0.0 0.1 GO:0016560 protein import into peroxisome matrix, docking(GO:0016560) protein to membrane docking(GO:0022615)
0.0 0.0 GO:0000196 MAPK cascade involved in cell wall organization or biogenesis(GO:0000196)
0.0 0.3 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 0.1 GO:0006562 proline catabolic process(GO:0006562) proline catabolic process to glutamate(GO:0010133) regulation of cellular amine catabolic process(GO:0033241)
0.0 0.1 GO:0009098 leucine biosynthetic process(GO:0009098)
0.0 0.1 GO:0015846 polyamine transport(GO:0015846)
0.0 0.1 GO:0046470 phosphatidylcholine metabolic process(GO:0046470)
0.0 0.4 GO:0051783 regulation of nuclear division(GO:0051783)
0.0 0.4 GO:0008033 tRNA processing(GO:0008033)
0.0 0.1 GO:0009102 biotin metabolic process(GO:0006768) biotin biosynthetic process(GO:0009102)
0.0 0.5 GO:0055072 iron ion homeostasis(GO:0055072)
0.0 0.0 GO:0046473 phosphatidic acid biosynthetic process(GO:0006654) phosphatidic acid metabolic process(GO:0046473)
0.0 0.0 GO:0043419 urea catabolic process(GO:0043419)
0.0 0.2 GO:0006541 glutamine metabolic process(GO:0006541)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.6 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.7 2.1 GO:0017102 methionyl glutamyl tRNA synthetase complex(GO:0017102)
0.5 1.5 GO:0005854 nascent polypeptide-associated complex(GO:0005854)
0.5 1.5 GO:0071261 Ssh1 translocon complex(GO:0071261)
0.5 2.4 GO:0030689 Noc complex(GO:0030689)
0.5 1.4 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.4 1.2 GO:0034457 Mpp10 complex(GO:0034457)
0.4 2.0 GO:0043614 multi-eIF complex(GO:0043614)
0.4 2.6 GO:0016459 myosin complex(GO:0016459)
0.4 3.4 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.4 1.8 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.4 1.1 GO:0005845 mRNA cap binding complex(GO:0005845)
0.4 1.4 GO:0070860 RNA polymerase I core factor complex(GO:0070860)
0.3 1.0 GO:0031417 NatC complex(GO:0031417)
0.3 1.0 GO:0005827 polar microtubule(GO:0005827) tubulin complex(GO:0045298)
0.3 1.0 GO:0070545 PeBoW complex(GO:0070545)
0.3 1.0 GO:0030874 nucleolar chromatin(GO:0030874)
0.3 1.8 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.3 4.2 GO:0030118 clathrin coat(GO:0030118)
0.3 0.9 GO:0051286 cell tip(GO:0051286)
0.3 0.3 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.3 1.1 GO:0017053 transcriptional repressor complex(GO:0017053)
0.3 0.8 GO:0072687 meiotic spindle(GO:0072687)
0.3 1.1 GO:0005822 inner plaque of spindle pole body(GO:0005822)
0.3 0.3 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.3 3.0 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.2 1.7 GO:0044614 nuclear pore cytoplasmic filaments(GO:0044614)
0.2 1.4 GO:0043527 tRNA methyltransferase complex(GO:0043527)
0.2 1.6 GO:0033180 vacuolar proton-transporting V-type ATPase, V1 domain(GO:0000221) proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.2 0.4 GO:0000229 cytoplasmic chromosome(GO:0000229) mitochondrial chromosome(GO:0000262)
0.2 1.1 GO:0005641 nuclear envelope lumen(GO:0005641)
0.2 2.7 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.2 0.4 GO:0032545 CURI complex(GO:0032545)
0.2 1.3 GO:0016272 prefoldin complex(GO:0016272)
0.2 11.0 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.2 0.9 GO:0034044 exomer complex(GO:0034044)
0.2 0.5 GO:0070209 ASTRA complex(GO:0070209)
0.2 0.9 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)
0.2 3.2 GO:0016586 RSC complex(GO:0016586)
0.2 0.7 GO:0031429 box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588)
0.2 0.9 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.2 7.4 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.2 0.7 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.2 1.0 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.2 15.4 GO:0022626 cytosolic ribosome(GO:0022626)
0.2 0.7 GO:0031205 endoplasmic reticulum Sec complex(GO:0031205) Sec62/Sec63 complex(GO:0031207)
0.2 0.6 GO:0030906 retromer, cargo-selective complex(GO:0030906)
0.2 0.9 GO:0048500 signal recognition particle, endoplasmic reticulum targeting(GO:0005786) signal recognition particle(GO:0048500)
0.2 0.6 GO:0005724 nuclear heterochromatin(GO:0005720) nuclear telomeric heterochromatin(GO:0005724) telomeric heterochromatin(GO:0031933)
0.2 0.9 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.2 0.5 GO:0016363 nuclear matrix(GO:0016363)
0.2 0.3 GO:0034518 RNA cap binding complex(GO:0034518)
0.2 1.1 GO:0072686 mitotic spindle(GO:0072686)
0.1 1.9 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)
0.1 0.4 GO:0070985 TFIIK complex(GO:0070985)
0.1 2.1 GO:0046695 SLIK (SAGA-like) complex(GO:0046695)
0.1 1.0 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.1 1.1 GO:0005688 U6 snRNP(GO:0005688)
0.1 0.4 GO:0033186 CAF-1 complex(GO:0033186)
0.1 0.4 GO:0005955 calcineurin complex(GO:0005955)
0.1 0.5 GO:0033100 NuA3 histone acetyltransferase complex(GO:0033100) H3 histone acetyltransferase complex(GO:0070775)
0.1 0.6 GO:0031262 Ndc80 complex(GO:0031262)
0.1 2.1 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.1 0.5 GO:0031105 septin complex(GO:0031105)
0.1 0.7 GO:0030126 COPI vesicle coat(GO:0030126)
0.1 4.9 GO:0030686 90S preribosome(GO:0030686)
0.1 0.5 GO:0030869 RENT complex(GO:0030869)
0.1 0.5 GO:0032221 Rpd3S complex(GO:0032221)
0.1 0.4 GO:0033254 vacuolar transporter chaperone complex(GO:0033254)
0.1 0.4 GO:0000792 heterochromatin(GO:0000792)
0.1 0.8 GO:0000782 telomere cap complex(GO:0000782) nuclear telomere cap complex(GO:0000783)
0.1 0.3 GO:0044611 nuclear pore inner ring(GO:0044611)
0.1 10.5 GO:0005730 nucleolus(GO:0005730)
0.1 0.6 GO:0044615 nuclear pore nuclear basket(GO:0044615)
0.1 0.5 GO:0000136 alpha-1,6-mannosyltransferase complex(GO:0000136)
0.1 1.2 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.1 1.2 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.1 0.6 GO:0019774 proteasome core complex, beta-subunit complex(GO:0019774)
0.1 0.3 GO:0032301 MutSalpha complex(GO:0032301)
0.1 0.9 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.1 0.3 GO:0005971 ribonucleoside-diphosphate reductase complex(GO:0005971)
0.1 0.6 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.1 0.9 GO:0042575 DNA polymerase complex(GO:0042575)
0.1 1.6 GO:0005844 polysome(GO:0005844)
0.1 0.6 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.1 0.5 GO:0005871 kinesin complex(GO:0005871)
0.1 0.4 GO:0032126 eisosome(GO:0032126)
0.1 0.6 GO:0090544 SWI/SNF complex(GO:0016514) BAF-type complex(GO:0090544)
0.1 0.1 GO:0032156 septin cytoskeleton(GO:0032156)
0.1 1.2 GO:0031314 extrinsic component of mitochondrial inner membrane(GO:0031314)
0.1 0.3 GO:0001401 mitochondrial sorting and assembly machinery complex(GO:0001401)
0.1 0.1 GO:0071819 DUBm complex(GO:0071819)
0.1 0.5 GO:0071007 U2-type catalytic step 2 spliceosome(GO:0071007) catalytic step 2 spliceosome(GO:0071013)
0.1 0.1 GO:0034271 phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271)
0.1 0.6 GO:0034399 nuclear periphery(GO:0034399)
0.1 0.4 GO:0031080 nuclear pore outer ring(GO:0031080)
0.1 0.2 GO:0005797 Golgi medial cisterna(GO:0005797)
0.1 0.3 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.1 0.8 GO:0000786 nucleosome(GO:0000786)
0.1 0.7 GO:0005686 U2 snRNP(GO:0005686)
0.1 0.9 GO:0036387 nuclear pre-replicative complex(GO:0005656) pre-replicative complex(GO:0036387)
0.1 0.2 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.1 0.2 GO:0016471 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220) vacuolar proton-transporting V-type ATPase complex(GO:0016471) proton-transporting V-type ATPase complex(GO:0033176) proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.1 0.2 GO:0044462 cell wall part(GO:0044426) external encapsulating structure part(GO:0044462)
0.1 0.9 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.1 0.2 GO:0000137 Golgi cis cisterna(GO:0000137)
0.0 0.2 GO:0030907 MBF transcription complex(GO:0030907)
0.0 6.0 GO:0005935 cellular bud neck(GO:0005935)
0.0 0.3 GO:0070772 PAS complex(GO:0070772)
0.0 0.2 GO:0000815 ESCRT III complex(GO:0000815)
0.0 0.1 GO:0031518 CBF3 complex(GO:0031518)
0.0 1.4 GO:0005643 nuclear pore(GO:0005643)
0.0 0.1 GO:0031985 Golgi cisterna(GO:0031985)
0.0 0.2 GO:0035361 Cul8-RING ubiquitin ligase complex(GO:0035361)
0.0 0.2 GO:0005849 mRNA cleavage factor complex(GO:0005849)
0.0 0.3 GO:0071006 U2-type catalytic step 1 spliceosome(GO:0071006) catalytic step 1 spliceosome(GO:0071012)
0.0 0.4 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
0.0 0.1 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.0 0.1 GO:0005791 rough endoplasmic reticulum(GO:0005791) rough endoplasmic reticulum membrane(GO:0030867)
0.0 0.1 GO:0042721 mitochondrial inner membrane protein insertion complex(GO:0042721)
0.0 0.4 GO:0031298 replication fork protection complex(GO:0031298)
0.0 0.1 GO:0035649 Nrd1 complex(GO:0035649)
0.0 0.1 GO:0005795 Golgi stack(GO:0005795)
0.0 0.1 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 0.3 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.0 0.2 GO:0031011 Ino80 complex(GO:0031011)
0.0 0.1 GO:0017059 serine C-palmitoyltransferase complex(GO:0017059) SPOTS complex(GO:0035339)
0.0 0.5 GO:0000781 chromosome, telomeric region(GO:0000781)
0.0 1.2 GO:0005635 nuclear envelope(GO:0005635)
0.0 0.3 GO:0005657 replication fork(GO:0005657)
0.0 0.1 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.0 0.1 GO:0031502 dolichyl-phosphate-mannose-protein mannosyltransferase complex(GO:0031502)
0.0 0.5 GO:0015935 small ribosomal subunit(GO:0015935)
0.0 0.2 GO:0033698 Rpd3L complex(GO:0033698)
0.0 0.5 GO:0005933 cellular bud(GO:0005933)
0.0 0.6 GO:0061645 actin cortical patch(GO:0030479) endocytic patch(GO:0061645)
0.0 0.1 GO:0034448 EGO complex(GO:0034448)
0.0 0.1 GO:0000818 MIS12/MIND type complex(GO:0000444) nuclear MIS12/MIND complex(GO:0000818)
0.0 0.3 GO:0098791 Golgi subcompartment(GO:0098791)
0.0 0.0 GO:0000124 SAGA complex(GO:0000124) SAGA-type complex(GO:0070461)
0.0 0.7 GO:0005856 cytoskeleton(GO:0005856)
0.0 0.6 GO:0000785 chromatin(GO:0000785)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 3.8 GO:0015114 phosphate ion transmembrane transporter activity(GO:0015114)
0.6 2.6 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.5 2.6 GO:0000146 microfilament motor activity(GO:0000146)
0.5 2.0 GO:0016841 ammonia-lyase activity(GO:0016841)
0.5 1.5 GO:0004809 tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
0.5 1.5 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.5 1.4 GO:0001169 transcription factor activity, RNA polymerase I CORE element sequence-specific binding(GO:0001169) transcription factor activity, RNA polymerase I CORE element binding transcription factor recruiting(GO:0001187)
0.5 5.6 GO:0030276 clathrin binding(GO:0030276)
0.4 3.4 GO:0001054 RNA polymerase I activity(GO:0001054)
0.4 1.8 GO:0002161 aminoacyl-tRNA editing activity(GO:0002161)
0.3 2.0 GO:0070300 phosphatidic acid binding(GO:0070300)
0.3 0.9 GO:0005519 cytoskeletal regulatory protein binding(GO:0005519)
0.3 2.3 GO:0031072 heat shock protein binding(GO:0031072)
0.3 0.8 GO:0051010 microtubule plus-end binding(GO:0051010)
0.3 2.6 GO:0031490 chromatin DNA binding(GO:0031490)
0.3 0.8 GO:0010521 telomerase inhibitor activity(GO:0010521)
0.3 1.3 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.3 0.8 GO:0097617 RNA strand annealing activity(GO:0033592) annealing activity(GO:0097617)
0.3 3.0 GO:0003968 RNA-directed RNA polymerase activity(GO:0003968)
0.2 0.7 GO:0051219 phosphoprotein binding(GO:0051219)
0.2 0.7 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.2 1.2 GO:0050072 m7G(5')pppN diphosphatase activity(GO:0050072)
0.2 0.7 GO:0000339 RNA cap binding(GO:0000339)
0.2 0.7 GO:0019003 GDP binding(GO:0019003)
0.2 0.9 GO:0003747 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.2 1.1 GO:0070403 NAD+ binding(GO:0070403)
0.2 1.1 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.2 6.4 GO:0004004 ATP-dependent RNA helicase activity(GO:0004004)
0.2 1.3 GO:0004022 alcohol dehydrogenase (NAD) activity(GO:0004022)
0.2 4.3 GO:0030515 snoRNA binding(GO:0030515)
0.2 0.8 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.2 0.6 GO:0016838 carbon-oxygen lyase activity, acting on phosphates(GO:0016838)
0.2 0.8 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.2 2.6 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.2 1.2 GO:0016408 C-acyltransferase activity(GO:0016408)
0.2 2.0 GO:0001133 RNA polymerase II transcription factor activity, sequence-specific transcription regulatory region DNA binding(GO:0001133)
0.2 1.0 GO:0008186 RNA-dependent ATPase activity(GO:0008186)
0.2 0.8 GO:0004771 sterol esterase activity(GO:0004771)
0.2 0.8 GO:0016886 ligase activity, forming phosphoric ester bonds(GO:0016886)
0.2 5.9 GO:0003743 translation initiation factor activity(GO:0003743)
0.2 0.6 GO:0016433 rRNA (adenine) methyltransferase activity(GO:0016433)
0.2 1.2 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.2 0.7 GO:0004622 lysophospholipase activity(GO:0004622)
0.2 0.8 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.2 0.5 GO:0003680 AT DNA binding(GO:0003680)
0.2 0.9 GO:0008312 7S RNA binding(GO:0008312)
0.2 2.8 GO:0042162 telomeric DNA binding(GO:0042162)
0.2 3.9 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.1 0.4 GO:0001179 RNA polymerase I transcription factor binding(GO:0001179) transcription factor activity, core RNA polymerase I binding(GO:0001181)
0.1 2.3 GO:0015616 DNA translocase activity(GO:0015616)
0.1 1.3 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.1 0.4 GO:0001094 TFIID-class transcription factor binding(GO:0001094)
0.1 0.5 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.1 8.7 GO:0003924 GTPase activity(GO:0003924)
0.1 0.5 GO:0043141 5'-3' DNA helicase activity(GO:0043139) ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.1 0.5 GO:0015230 FAD transmembrane transporter activity(GO:0015230)
0.1 1.3 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.1 0.4 GO:0070567 cytidylyltransferase activity(GO:0070567)
0.1 0.8 GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.1 1.0 GO:0015081 sodium ion transmembrane transporter activity(GO:0015081)
0.1 0.6 GO:0008536 Ran GTPase binding(GO:0008536)
0.1 1.3 GO:0004497 monooxygenase activity(GO:0004497)
0.1 0.4 GO:0016274 arginine N-methyltransferase activity(GO:0016273) protein-arginine N-methyltransferase activity(GO:0016274)
0.1 0.4 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity(GO:0004723)
0.1 0.4 GO:0000150 recombinase activity(GO:0000150)
0.1 0.5 GO:0000772 mating pheromone activity(GO:0000772) receptor binding(GO:0005102) pheromone activity(GO:0005186)
0.1 1.2 GO:0030295 protein kinase activator activity(GO:0030295)
0.1 4.7 GO:0019843 rRNA binding(GO:0019843)
0.1 0.6 GO:0016423 tRNA (guanine) methyltransferase activity(GO:0016423)
0.1 3.0 GO:0016875 aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)
0.1 1.7 GO:0003714 transcription corepressor activity(GO:0003714)
0.1 1.6 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.1 6.0 GO:0044822 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.1 0.3 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.1 0.4 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.1 1.2 GO:0051015 actin filament binding(GO:0051015)
0.1 1.6 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.1 0.3 GO:0032296 ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296)
0.1 1.2 GO:0016891 endoribonuclease activity, producing 5'-phosphomonoesters(GO:0016891)
0.1 1.2 GO:0070491 repressing transcription factor binding(GO:0070491)
0.1 0.4 GO:0000297 spermine transmembrane transporter activity(GO:0000297)
0.1 0.3 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.1 2.5 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.1 0.5 GO:0003724 RNA helicase activity(GO:0003724)
0.1 0.3 GO:0016670 oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor(GO:0016670) thiol oxidase activity(GO:0016972)
0.1 0.4 GO:0051183 vitamin transporter activity(GO:0051183)
0.1 15.7 GO:0003735 structural constituent of ribosome(GO:0003735)
0.1 0.6 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.1 0.3 GO:0061731 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups(GO:0016725) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.1 0.2 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.1 0.5 GO:0008409 5'-3' exonuclease activity(GO:0008409)
0.1 0.3 GO:0008198 ferrous iron binding(GO:0008198)
0.1 1.6 GO:0019001 GTP binding(GO:0005525) guanyl nucleotide binding(GO:0019001) guanyl ribonucleotide binding(GO:0032561)
0.1 0.9 GO:0008599 protein phosphatase type 1 regulator activity(GO:0008599)
0.1 0.4 GO:0017048 Rho GTPase binding(GO:0017048)
0.1 1.0 GO:0004659 prenyltransferase activity(GO:0004659)
0.1 0.3 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.1 0.3 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.1 0.2 GO:0009922 fatty acid elongase activity(GO:0009922)
0.1 0.5 GO:0003777 microtubule motor activity(GO:0003777)
0.1 1.3 GO:0008408 3'-5' exonuclease activity(GO:0008408)
0.1 0.6 GO:0000991 transcription factor activity, core RNA polymerase II binding(GO:0000991)
0.1 0.9 GO:0015238 drug transmembrane transporter activity(GO:0015238)
0.1 0.5 GO:0000009 alpha-1,6-mannosyltransferase activity(GO:0000009)
0.1 0.1 GO:0005487 nucleocytoplasmic transporter activity(GO:0005487)
0.1 1.8 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)
0.1 0.2 GO:0036002 pre-mRNA binding(GO:0036002)
0.1 0.5 GO:0019239 deaminase activity(GO:0019239)
0.1 0.5 GO:0004713 protein tyrosine kinase activity(GO:0004713)
0.1 0.1 GO:0015248 sterol transporter activity(GO:0015248)
0.1 0.6 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.1 1.5 GO:0015631 tubulin binding(GO:0015631)
0.1 0.7 GO:0043021 ribonucleoprotein complex binding(GO:0043021)
0.1 1.3 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.1 3.5 GO:0003682 chromatin binding(GO:0003682)
0.1 0.5 GO:0019213 deacetylase activity(GO:0019213)
0.0 0.2 GO:0032934 steroid binding(GO:0005496) sterol binding(GO:0032934)
0.0 0.9 GO:0005319 lipid transporter activity(GO:0005319)
0.0 0.2 GO:0008252 nucleotidase activity(GO:0008252)
0.0 0.1 GO:0030943 mitochondrion targeting sequence binding(GO:0030943)
0.0 0.6 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.0 0.4 GO:0016646 oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor(GO:0016646)
0.0 0.0 GO:0043178 alcohol binding(GO:0043178)
0.0 0.4 GO:0000182 rDNA binding(GO:0000182)
0.0 0.6 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 0.3 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 5.6 GO:0003723 RNA binding(GO:0003723)
0.0 0.9 GO:0003779 actin binding(GO:0003779)
0.0 0.9 GO:0042393 histone binding(GO:0042393)
0.0 0.4 GO:0019205 nucleobase-containing compound kinase activity(GO:0019205)
0.0 0.1 GO:0043142 single-stranded DNA-dependent ATPase activity(GO:0043142)
0.0 0.1 GO:0000156 phosphorelay response regulator activity(GO:0000156)
0.0 0.7 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765)
0.0 0.2 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.0 0.5 GO:0101005 thiol-dependent ubiquitin-specific protease activity(GO:0004843) thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.0 1.2 GO:0016791 phosphatase activity(GO:0016791)
0.0 0.1 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.1 GO:0019901 protein kinase binding(GO:0019901)
0.0 0.3 GO:0003684 damaged DNA binding(GO:0003684)
0.0 0.1 GO:0015203 polyamine transmembrane transporter activity(GO:0015203)
0.0 0.0 GO:0016840 carbon-nitrogen lyase activity(GO:0016840)
0.0 0.5 GO:0008094 DNA-dependent ATPase activity(GO:0008094)
0.0 0.1 GO:0005338 nucleotide-sugar transmembrane transporter activity(GO:0005338)
0.0 0.1 GO:0019237 centromeric DNA binding(GO:0019237)
0.0 0.1 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 2.1 GO:0004674 protein serine/threonine kinase activity(GO:0004674)
0.0 0.1 GO:0070569 uridylyltransferase activity(GO:0070569)
0.0 0.3 GO:0050661 NADP binding(GO:0050661)
0.0 0.2 GO:0042803 protein homodimerization activity(GO:0042803)
0.0 0.1 GO:0008172 S-methyltransferase activity(GO:0008172)
0.0 0.8 GO:0008565 protein transporter activity(GO:0008565)
0.0 0.2 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887) DNA polymerase activity(GO:0034061)
0.0 0.1 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 0.1 GO:0000384 first spliceosomal transesterification activity(GO:0000384)
0.0 0.1 GO:0005310 dicarboxylic acid transmembrane transporter activity(GO:0005310)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.2 PID SHP2 PATHWAY SHP2 signaling
0.3 1.4 PID E2F PATHWAY E2F transcription factor network
0.3 0.9 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.2 0.2 ST JNK MAPK PATHWAY JNK MAPK Pathway
0.2 0.9 PID P73PATHWAY p73 transcription factor network
0.2 0.5 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.1 0.4 PID LKB1 PATHWAY LKB1 signaling events
0.1 0.4 PID MYC PATHWAY C-MYC pathway
0.1 0.5 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 0.0 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.7 REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements
0.5 1.5 REACTOME SIGNALLING TO ERKS Genes involved in Signalling to ERKs
0.4 1.3 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.4 1.2 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.4 0.7 REACTOME G1 PHASE Genes involved in G1 Phase
0.3 2.2 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.3 0.9 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.3 0.8 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.2 1.6 REACTOME DEADENYLATION DEPENDENT MRNA DECAY Genes involved in Deadenylation-dependent mRNA decay
0.1 0.9 REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.1 0.4 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.1 0.4 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.1 1.4 REACTOME TRANSCRIPTION Genes involved in Transcription
0.1 0.7 REACTOME EXTENSION OF TELOMERES Genes involved in Extension of Telomeres
0.1 1.2 REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION Genes involved in Influenza Viral RNA Transcription and Replication
0.1 0.2 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.1 0.2 REACTOME METABOLISM OF RNA Genes involved in Metabolism of RNA
0.1 0.5 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 0.7 REACTOME MITOTIC G1 G1 S PHASES Genes involved in Mitotic G1-G1/S phases
0.0 0.1 REACTOME SHC1 EVENTS IN ERBB4 SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.0 0.0 REACTOME SIGNALING BY ERBB4 Genes involved in Signaling by ERBB4
0.0 0.0 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.2 REACTOME ASPARAGINE N LINKED GLYCOSYLATION Genes involved in Asparagine N-linked glycosylation