Results for REB1
Z-value: 0.92
Motif logo
Transcription factors associated with REB1
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
|
REB1
|
S000000253 | RNA polymerase I enhancer binding protein |
Activity-expression correlation:
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| YLR154W-A Show fit | 5.41 |
Dubious open reading frame unlikely to encode a protein; encoded within the the 25S rRNA gene on the opposite strand |
||
| YLR154W-B Show fit | 4.83 |
Dubious open reading frame unlikely to encode a protein; encoded within the the 25S rRNA gene on the opposite strand |
||
| YLR154W-C Show fit | 4.04 |
Mitochondrial protein of unknown function, overexpression suppresses an rpo41 mutation affecting mitochondrial RNA polymerase; encoded within the 25S rRNA gene on the opposite strand |
||
| YNR013C Show fit | 3.55 |
Low-affinity phosphate transporter of the vacuolar membrane; deletion of pho84, pho87, pho89, pho90, and pho91 causes synthetic lethality; transcription independent of Pi and Pho4p activity; overexpression results in vigorous growth |
||
| YGR242W Show fit | 3.08 |
Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified ORF YAP1802/YGR241C |
||
| YFL015W-A Show fit | 2.95 |
Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data |
||
| YGR241C Show fit | 2.58 |
Protein involved in clathrin cage assembly; binds Pan1p and clathrin; homologous to Yap1801p, member of the AP180 protein family |
||
| YLR154C Show fit | 2.56 |
Ribonuclease H2 subunit, required for RNase H2 activity |
||
| YCR031C Show fit | 2.55 |
Ribosomal protein 59 of the small subunit, required for ribosome assembly and 20S pre-rRNA processing; mutations confer cryptopleurine resistance; nearly identical to Rps14Bp and similar to E. coli S11 and rat S14 ribosomal proteins |
||
| YFL015C Show fit | 2.48 |
Dubious open reading frame unlikely to encode a protein; partially overlaps dubious ORF YFL015W-A; YFL015C is not an essential gene |
Network of associatons between targets according to the STRING database.
First level regulatory network of REB1
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 16.6 | GO:0006364 | rRNA processing(GO:0006364) |
| 0.1 | 13.6 | GO:0002181 | cytoplasmic translation(GO:0002181) |
| 0.2 | 7.8 | GO:0000027 | ribosomal large subunit assembly(GO:0000027) |
| 0.6 | 5.4 | GO:0006814 | sodium ion transport(GO:0006814) |
| 0.2 | 5.3 | GO:0000184 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184) |
| 0.2 | 4.6 | GO:0002097 | tRNA wobble base modification(GO:0002097) tRNA wobble uridine modification(GO:0002098) |
| 0.1 | 4.6 | GO:0098876 | Golgi to plasma membrane transport(GO:0006893) vesicle-mediated transport to the plasma membrane(GO:0098876) |
| 0.2 | 4.3 | GO:0051029 | rRNA export from nucleus(GO:0006407) rRNA transport(GO:0051029) |
| 0.2 | 3.7 | GO:0006369 | termination of RNA polymerase II transcription(GO:0006369) |
| 0.2 | 3.3 | GO:0000028 | ribosomal small subunit assembly(GO:0000028) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 15.4 | GO:0022626 | cytosolic ribosome(GO:0022626) |
| 0.2 | 11.0 | GO:0022627 | cytosolic small ribosomal subunit(GO:0022627) |
| 0.1 | 10.5 | GO:0005730 | nucleolus(GO:0005730) |
| 0.2 | 7.4 | GO:0030687 | preribosome, large subunit precursor(GO:0030687) |
| 0.0 | 6.0 | GO:0005935 | cellular bud neck(GO:0005935) |
| 0.1 | 4.9 | GO:0030686 | 90S preribosome(GO:0030686) |
| 0.3 | 4.2 | GO:0030118 | clathrin coat(GO:0030118) |
| 0.4 | 3.4 | GO:0005736 | DNA-directed RNA polymerase I complex(GO:0005736) |
| 0.2 | 3.2 | GO:0016586 | RSC complex(GO:0016586) |
| 0.3 | 3.0 | GO:0005665 | DNA-directed RNA polymerase II, core complex(GO:0005665) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 15.7 | GO:0003735 | structural constituent of ribosome(GO:0003735) |
| 0.1 | 8.7 | GO:0003924 | GTPase activity(GO:0003924) |
| 0.2 | 6.4 | GO:0004004 | ATP-dependent RNA helicase activity(GO:0004004) |
| 0.1 | 6.0 | GO:0044822 | mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822) |
| 0.2 | 5.9 | GO:0003743 | translation initiation factor activity(GO:0003743) |
| 0.5 | 5.6 | GO:0030276 | clathrin binding(GO:0030276) |
| 0.0 | 5.6 | GO:0003723 | RNA binding(GO:0003723) |
| 0.1 | 4.7 | GO:0019843 | rRNA binding(GO:0019843) |
| 0.2 | 4.3 | GO:0030515 | snoRNA binding(GO:0030515) |
| 0.2 | 3.9 | GO:0016538 | cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 1.4 | PID E2F PATHWAY | E2F transcription factor network |
| 0.4 | 1.2 | PID SHP2 PATHWAY | SHP2 signaling |
| 0.3 | 0.9 | SA G1 AND S PHASES | Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition. |
| 0.2 | 0.9 | PID P73PATHWAY | p73 transcription factor network |
| 0.2 | 0.5 | PID P38 ALPHA BETA DOWNSTREAM PATHWAY | Signaling mediated by p38-alpha and p38-beta |
| 0.1 | 0.5 | NABA SECRETED FACTORS | Genes encoding secreted soluble factors |
| 0.1 | 0.4 | PID LKB1 PATHWAY | LKB1 signaling events |
| 0.1 | 0.4 | PID MYC PATHWAY | C-MYC pathway |
| 0.2 | 0.2 | ST JNK MAPK PATHWAY | JNK MAPK Pathway |
| 0.0 | 0.0 | SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES | Genes related to the insulin receptor pathway |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 2.2 | REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX | Genes involved in Formation of the ternary complex, and subsequently, the 43S complex |
| 0.6 | 1.7 | REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS | Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements |
| 0.2 | 1.6 | REACTOME DEADENYLATION DEPENDENT MRNA DECAY | Genes involved in Deadenylation-dependent mRNA decay |
| 0.5 | 1.5 | REACTOME SIGNALLING TO ERKS | Genes involved in Signalling to ERKs |
| 0.1 | 1.4 | REACTOME TRANSCRIPTION | Genes involved in Transcription |
| 0.4 | 1.3 | REACTOME SIGNALING BY RHO GTPASES | Genes involved in Signaling by Rho GTPases |
| 0.4 | 1.2 | REACTOME MHC CLASS II ANTIGEN PRESENTATION | Genes involved in MHC class II antigen presentation |
| 0.1 | 1.2 | REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION | Genes involved in Influenza Viral RNA Transcription and Replication |
| 0.3 | 0.9 | REACTOME CITRIC ACID CYCLE TCA CYCLE | Genes involved in Citric acid cycle (TCA cycle) |
| 0.1 | 0.9 | REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC | Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC |