Results for RDS2
Z-value: 0.69
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Transcription factors associated with RDS2
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
|
RDS2
|
S000006054 | Transcription factor involved in regulating gluconeogenesis |
Activity-expression correlation:
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| YDR536W Show fit | 2.43 |
Glycerol proton symporter of the plasma membrane, subject to glucose-induced inactivation, strongly but transiently induced when cells are subjected to osmotic shock |
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| YIR039C Show fit | 2.28 |
Putative GPI-anchored aspartic protease |
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| YNL160W Show fit | 2.27 |
Cell wall-related secretory glycoprotein; induced by nutrient deprivation-associated growth arrest and upon entry into stationary phase; may be involved in adaptation prior to stationary phase entry; has similarity to Sps100p |
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| YDR343C Show fit | 2.20 |
High-affinity glucose transporter of the major facilitator superfamily, nearly identical to Hxt7p, expressed at high basal levels relative to other HXTs, repression of expression by high glucose requires SNF3 |
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| YER065C Show fit | 2.14 |
Isocitrate lyase, catalyzes the formation of succinate and glyoxylate from isocitrate, a key reaction of the glyoxylate cycle; expression of ICL1 is induced by growth on ethanol and repressed by growth on glucose |
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| YEL065W Show fit | 2.12 |
Ferrioxamine B transporter, member of the ARN family of transporters that specifically recognize siderophore-iron chelates; transcription is induced during iron deprivation and diauxic shift; potentially phosphorylated by Cdc28p |
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| YDR342C Show fit | 2.11 |
High-affinity glucose transporter of the major facilitator superfamily, nearly identical to Hxt6p, expressed at high basal levels relative to other HXTs, expression repressed by high glucose levels |
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| YER150W Show fit | 2.06 |
GPI-anchored cell wall protein involved in weak acid resistance; basal expression requires Msn2p/Msn4p; expression is induced under conditions of stress and during the diauxic shift; similar to Sed1p |
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| YEL008W Show fit | 2.03 |
Hypothetical protein predicted to be involved in metabolism |
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| YCR021C Show fit | 2.00 |
Hydrophobic plasma membrane localized, stress-responsive protein that negatively regulates the H(+)-ATPase Pma1p; induced by heat shock, ethanol treatment, weak organic acid, glucose limitation, and entry into stationary phase |
Network of associatons between targets according to the STRING database.
First level regulatory network of RDS2
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 5.1 | GO:0045229 | external encapsulating structure organization(GO:0045229) cell wall organization(GO:0071555) |
| 0.2 | 4.0 | GO:0015749 | hexose transport(GO:0008645) monosaccharide transport(GO:0015749) |
| 0.4 | 3.2 | GO:0015891 | siderophore transport(GO:0015891) |
| 0.2 | 3.0 | GO:0015985 | energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986) |
| 0.3 | 2.8 | GO:0006097 | glyoxylate cycle(GO:0006097) |
| 0.1 | 2.7 | GO:0006094 | gluconeogenesis(GO:0006094) |
| 0.1 | 2.5 | GO:0070726 | cell wall assembly(GO:0070726) |
| 0.5 | 2.3 | GO:0015793 | glycerol transport(GO:0015793) |
| 0.7 | 2.0 | GO:0032780 | negative regulation of ATPase activity(GO:0032780) |
| 0.2 | 2.0 | GO:0019878 | lysine biosynthetic process via aminoadipic acid(GO:0019878) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 8.8 | GO:0031225 | anchored component of membrane(GO:0031225) |
| 0.0 | 7.8 | GO:0005886 | plasma membrane(GO:0005886) |
| 0.0 | 6.1 | GO:0005740 | mitochondrial envelope(GO:0005740) |
| 0.1 | 3.8 | GO:0005576 | extracellular region(GO:0005576) |
| 0.1 | 3.1 | GO:0005758 | mitochondrial intermembrane space(GO:0005758) |
| 0.0 | 3.0 | GO:0010008 | endosome membrane(GO:0010008) |
| 0.0 | 2.6 | GO:0044429 | mitochondrial part(GO:0044429) |
| 0.2 | 2.3 | GO:0045121 | membrane raft(GO:0045121) membrane microdomain(GO:0098857) |
| 0.1 | 2.3 | GO:0031903 | peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903) |
| 0.6 | 1.7 | GO:0046930 | pore complex(GO:0046930) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 3.1 | GO:0051082 | unfolded protein binding(GO:0051082) |
| 0.6 | 3.0 | GO:0015295 | solute:proton symporter activity(GO:0015295) |
| 0.2 | 3.0 | GO:0005353 | fructose transmembrane transporter activity(GO:0005353) mannose transmembrane transporter activity(GO:0015578) |
| 0.7 | 2.9 | GO:0015603 | siderophore transmembrane transporter activity(GO:0015343) iron chelate transmembrane transporter activity(GO:0015603) siderophore transporter activity(GO:0042927) |
| 0.3 | 2.7 | GO:0070001 | aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001) |
| 0.4 | 2.6 | GO:0016833 | oxo-acid-lyase activity(GO:0016833) |
| 0.2 | 2.5 | GO:0046933 | proton-transporting ATP synthase activity, rotational mechanism(GO:0046933) |
| 0.2 | 2.2 | GO:0010181 | FMN binding(GO:0010181) |
| 0.5 | 2.1 | GO:0004396 | hexokinase activity(GO:0004396) |
| 0.2 | 2.1 | GO:0005199 | structural constituent of cell wall(GO:0005199) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.7 | 2.1 | PID IL4 2PATHWAY | IL4-mediated signaling events |
| 0.5 | 1.5 | PID HNF3B PATHWAY | FOXA2 and FOXA3 transcription factor networks |
| 0.2 | 1.2 | PID MYC ACTIV PATHWAY | Validated targets of C-MYC transcriptional activation |
| 0.1 | 0.4 | PID PLK1 PATHWAY | PLK1 signaling events |
| 0.1 | 0.2 | NABA ECM REGULATORS | Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix |
| 0.0 | 0.2 | PID FANCONI PATHWAY | Fanconi anemia pathway |
| 0.0 | 0.1 | PID CMYB PATHWAY | C-MYB transcription factor network |
| 0.0 | 0.1 | PID P73PATHWAY | p73 transcription factor network |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.4 | 3.2 | REACTOME GLUCONEOGENESIS | Genes involved in Gluconeogenesis |
| 0.2 | 0.7 | REACTOME METABOLISM OF POLYAMINES | Genes involved in Metabolism of polyamines |
| 0.1 | 0.6 | REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS | Genes involved in Apoptotic cleavage of cellular proteins |
| 0.0 | 0.6 | REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN | Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein |
| 0.2 | 0.5 | REACTOME MEIOTIC SYNAPSIS | Genes involved in Meiotic Synapsis |
| 0.1 | 0.5 | REACTOME MEIOSIS | Genes involved in Meiosis |
| 0.1 | 0.3 | REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS | Genes involved in Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. |
| 0.1 | 0.2 | REACTOME ETHANOL OXIDATION | Genes involved in Ethanol oxidation |
| 0.1 | 0.2 | REACTOME RIG I MDA5 MEDIATED INDUCTION OF IFN ALPHA BETA PATHWAYS | Genes involved in RIG-I/MDA5 mediated induction of IFN-alpha/beta pathways |
| 0.0 | 0.2 | REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES | Genes involved in Metabolism of amino acids and derivatives |