Results for RDS1
Z-value: 0.73
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Transcription factors associated with RDS1
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
|
RDS1
|
S000000703 | Putative zinc cluster transcription factor |
Activity-expression correlation:
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| YCL025C Show fit | 3.54 |
Low-affinity amino acid permease with broad substrate range, involved in uptake of asparagine, glutamine, and other amino acids; expression is regulated by the SPS plasma membrane amino acid sensor system (Ssy1p-Ptr3p-Ssy5p) |
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| YKL217W Show fit | 2.90 |
Lactate transporter, required for uptake of lactate and pyruvate; phosphorylated; expression is derepressed by transcriptional activator Cat8p during respiratory growth, and repressed in the presence of glucose, fructose, and mannose |
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| YML089C Show fit | 2.36 |
Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data; expression induced by calcium shortage |
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| YJL089W Show fit | 2.35 |
C6 zinc cluster transcriptional activator that binds to the carbon source-responsive element (CSRE) of gluconeogenic genes; involved in the positive regulation of gluconeogenesis; regulated by Snf1p protein kinase; localized to the nucleus |
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| YBR230C Show fit | 2.16 |
Integral mitochondrial outer membrane protein; abundance is decreased in cells grown in glucose relative to other carbon sources; appears to contain 3 alpha-helical transmembrane segments; ORF encodes a 97-basepair intron |
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| YDL210W Show fit | 2.12 |
Permease that serves as a gamma-aminobutyrate (GABA) transport protein involved in the utilization of GABA as a nitrogen source; catalyzes the transport of putrescine and delta-aminolevulinic acid (ALA); localized to the vacuolar membrane |
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| YDR536W Show fit | 2.11 |
Glycerol proton symporter of the plasma membrane, subject to glucose-induced inactivation, strongly but transiently induced when cells are subjected to osmotic shock |
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| YJL133C-A Show fit | 1.99 |
Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies |
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| YOL131W Show fit | 1.89 |
Putative protein of unknown function |
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| YGR236C Show fit | 1.75 |
Protein required for survival at high temperature during stationary phase; not required for growth on nonfermentable carbon sources; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies |
Network of associatons between targets according to the STRING database.
First level regulatory network of RDS1
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 3.4 | GO:0098656 | anion transmembrane transport(GO:0098656) |
| 0.8 | 3.3 | GO:0006848 | pyruvate transport(GO:0006848) |
| 1.0 | 3.0 | GO:0061414 | regulation of gluconeogenesis by regulation of transcription from RNA polymerase II promoter(GO:0035947) positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948) regulation of transcription from RNA polymerase II promoter by a nonfermentable carbon source(GO:0061413) positive regulation of transcription from RNA polymerase II promoter by a nonfermentable carbon source(GO:0061414) |
| 0.4 | 2.7 | GO:0006083 | acetate metabolic process(GO:0006083) |
| 0.1 | 2.7 | GO:0019740 | nitrogen utilization(GO:0019740) |
| 0.8 | 2.5 | GO:0009437 | amino-acid betaine metabolic process(GO:0006577) carnitine metabolic process(GO:0009437) |
| 0.5 | 2.0 | GO:0015847 | putrescine transport(GO:0015847) |
| 0.1 | 1.8 | GO:0008608 | attachment of spindle microtubules to kinetochore(GO:0008608) |
| 0.2 | 1.7 | GO:0015985 | energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986) |
| 0.3 | 1.6 | GO:0015793 | glycerol transport(GO:0015793) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 10.4 | GO:0005739 | mitochondrion(GO:0005739) |
| 0.0 | 4.8 | GO:0000329 | fungal-type vacuole membrane(GO:0000329) lytic vacuole membrane(GO:0098852) |
| 0.1 | 3.3 | GO:0042579 | peroxisome(GO:0005777) microbody(GO:0042579) |
| 0.1 | 3.2 | GO:0005758 | mitochondrial intermembrane space(GO:0005758) |
| 0.0 | 2.9 | GO:0005743 | mitochondrial inner membrane(GO:0005743) |
| 0.1 | 2.4 | GO:0031306 | intrinsic component of mitochondrial outer membrane(GO:0031306) integral component of mitochondrial outer membrane(GO:0031307) |
| 0.3 | 1.6 | GO:0045263 | mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276) proton-transporting ATP synthase complex, coupling factor F(o)(GO:0045263) |
| 0.1 | 1.5 | GO:0070469 | respiratory chain(GO:0070469) |
| 0.5 | 1.4 | GO:0045265 | mitochondrial proton-transporting ATP synthase, stator stalk(GO:0000274) proton-transporting ATP synthase, stator stalk(GO:0045265) |
| 0.2 | 1.4 | GO:0045239 | tricarboxylic acid cycle enzyme complex(GO:0045239) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.4 | 7.0 | GO:0015295 | solute:proton symporter activity(GO:0015295) |
| 0.1 | 5.2 | GO:0001228 | transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077) transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228) |
| 0.3 | 3.0 | GO:0046933 | proton-transporting ATP synthase activity, rotational mechanism(GO:0046933) |
| 0.8 | 2.5 | GO:0004092 | carnitine O-acetyltransferase activity(GO:0004092) carnitine O-acyltransferase activity(GO:0016406) |
| 0.1 | 2.5 | GO:0046906 | heme binding(GO:0020037) tetrapyrrole binding(GO:0046906) |
| 0.1 | 2.1 | GO:0008519 | ammonium transmembrane transporter activity(GO:0008519) |
| 0.5 | 2.0 | GO:0015193 | L-proline transmembrane transporter activity(GO:0015193) |
| 0.5 | 1.6 | GO:0016208 | AMP binding(GO:0016208) |
| 0.2 | 1.6 | GO:0015205 | nucleobase transmembrane transporter activity(GO:0015205) |
| 0.2 | 1.5 | GO:0001078 | transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 25.0 | ST GRANULE CELL SURVIVAL PATHWAY | Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway. |
| 0.2 | 0.5 | NABA ECM REGULATORS | Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix |
| 0.1 | 0.2 | PID FOXO PATHWAY | FoxO family signaling |
| 0.1 | 0.2 | PID TCR PATHWAY | TCR signaling in naïve CD4+ T cells |
| 0.0 | 0.2 | PID P73PATHWAY | p73 transcription factor network |
| 0.1 | 0.1 | PID ERBB2 ERBB3 PATHWAY | ErbB2/ErbB3 signaling events |
| 0.0 | 0.1 | PID FANCONI PATHWAY | Fanconi anemia pathway |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 25.0 | REACTOME CHONDROITIN SULFATE BIOSYNTHESIS | Genes involved in Chondroitin sulfate biosynthesis |
| 0.2 | 0.6 | REACTOME MEIOTIC SYNAPSIS | Genes involved in Meiotic Synapsis |
| 0.2 | 0.6 | REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS | Genes involved in Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. |
| 0.1 | 0.6 | REACTOME PYRUVATE METABOLISM AND CITRIC ACID TCA CYCLE | Genes involved in Pyruvate metabolism and Citric Acid (TCA) cycle |
| 0.1 | 0.4 | REACTOME DOUBLE STRAND BREAK REPAIR | Genes involved in Double-Strand Break Repair |
| 0.1 | 0.4 | REACTOME DNA REPAIR | Genes involved in DNA Repair |
| 0.0 | 0.3 | REACTOME GLUCONEOGENESIS | Genes involved in Gluconeogenesis |
| 0.0 | 0.1 | REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING | Genes involved in Downregulation of ERBB2:ERBB3 signaling |
| 0.0 | 0.1 | REACTOME METABOLISM OF POLYAMINES | Genes involved in Metabolism of polyamines |