Results for PUT3
Z-value: 0.69
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Transcription factors associated with PUT3
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
|
PUT3
|
S000001498 | Transcriptional activator of proline utilization genes, constitutivel |
Activity-expression correlation:
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| YAR035W Show fit | 3.93 |
Outer mitochondrial carnitine acetyltransferase, minor ethanol-inducible enzyme involved in transport of activated acyl groups from the cytoplasm into the mitochondrial matrix; phosphorylated |
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| YMR017W Show fit | 3.79 |
Meiosis-specific subunit of the t-SNARE complex, required for prospore membrane formation during sporulation; similar to but not functionally redundant with Sec9p; SNAP-25 homolog |
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| YPL026C Show fit | 3.28 |
Putative serine/threonine protein kinase; involved in the adaptation to low concentrations of glucose independent of the SNF3 regulated pathway |
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| YIL057C Show fit | 2.94 |
Putative protein of unknown function; expression induced under carbon limitation and repressed under high glucose |
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| YAR053W Show fit | 2.92 |
Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data |
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| YLR377C Show fit | 2.85 |
Fructose-1,6-bisphosphatase, key regulatory enzyme in the gluconeogenesis pathway, required for glucose metabolism |
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| YJR048W Show fit | 2.56 |
Cytochrome c, isoform 1; electron carrier of the mitochondrial intermembrane space that transfers electrons from ubiquinone-cytochrome c oxidoreductase to cytochrome c oxidase during cellular respiration |
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| YJR095W Show fit | 2.39 |
Mitochondrial succinate-fumarate transporter, transports succinate into and fumarate out of the mitochondrion; required for ethanol and acetate utilization |
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| YPL024W Show fit | 2.34 |
Involved in response to DNA damage; null mutants have increased rates of recombination and delayed S phase; interacts physically and genetically with Sgs1p (RecQ family member) and Top3p (topoisomerase III) |
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| YJL045W Show fit | 1.95 |
Minor succinate dehydrogenase isozyme; homologous to Sdh1p, the major isozyme reponsible for the oxidation of succinate and transfer of electrons to ubiquinone; induced during the diauxic shift in a Cat8p-dependent manner |
Network of associatons between targets according to the STRING database.
First level regulatory network of PUT3
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.7 | 8.0 | GO:0015758 | glucose transport(GO:0015758) |
| 0.5 | 4.8 | GO:0006097 | glyoxylate cycle(GO:0006097) |
| 1.5 | 4.6 | GO:0009437 | amino-acid betaine metabolic process(GO:0006577) carnitine metabolic process(GO:0009437) |
| 0.1 | 4.0 | GO:0009060 | aerobic respiration(GO:0009060) |
| 0.3 | 3.8 | GO:0031321 | ascospore-type prospore assembly(GO:0031321) |
| 0.2 | 2.8 | GO:0072593 | reactive oxygen species metabolic process(GO:0072593) |
| 0.3 | 2.7 | GO:0006123 | mitochondrial electron transport, cytochrome c to oxygen(GO:0006123) |
| 0.8 | 2.3 | GO:0034310 | ethanol catabolic process(GO:0006068) primary alcohol catabolic process(GO:0034310) |
| 0.6 | 2.3 | GO:0043388 | positive regulation of DNA binding(GO:0043388) regulation of DNA binding(GO:0051101) |
| 0.7 | 2.2 | GO:0015740 | C4-dicarboxylate transport(GO:0015740) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 8.0 | GO:0005743 | mitochondrial inner membrane(GO:0005743) |
| 0.2 | 4.6 | GO:0042763 | prospore membrane(GO:0005628) intracellular immature spore(GO:0042763) ascospore-type prospore(GO:0042764) |
| 0.0 | 4.1 | GO:0000794 | condensed nuclear chromosome(GO:0000794) |
| 0.2 | 4.0 | GO:0070469 | respiratory chain(GO:0070469) |
| 0.4 | 2.8 | GO:0042597 | periplasmic space(GO:0042597) |
| 0.8 | 2.4 | GO:0031422 | RecQ helicase-Topo III complex(GO:0031422) |
| 0.0 | 2.4 | GO:0005576 | extracellular region(GO:0005576) |
| 0.5 | 2.0 | GO:0016602 | CCAAT-binding factor complex(GO:0016602) |
| 0.2 | 2.0 | GO:0000276 | mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276) proton-transporting ATP synthase complex, coupling factor F(o)(GO:0045263) |
| 0.1 | 1.8 | GO:0031307 | intrinsic component of mitochondrial outer membrane(GO:0031306) integral component of mitochondrial outer membrane(GO:0031307) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.5 | 4.6 | GO:0004092 | carnitine O-acetyltransferase activity(GO:0004092) carnitine O-acyltransferase activity(GO:0016406) |
| 0.2 | 4.0 | GO:0005484 | SNAP receptor activity(GO:0005484) |
| 0.1 | 3.1 | GO:0001077 | transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077) transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228) |
| 0.0 | 3.0 | GO:0004674 | protein serine/threonine kinase activity(GO:0004674) |
| 0.0 | 2.8 | GO:0000981 | RNA polymerase II transcription factor activity, sequence-specific DNA binding(GO:0000981) |
| 0.5 | 2.7 | GO:0050308 | sugar-phosphatase activity(GO:0050308) |
| 0.1 | 2.7 | GO:0001102 | RNA polymerase II activating transcription factor binding(GO:0001102) |
| 0.2 | 2.5 | GO:0005199 | structural constituent of cell wall(GO:0005199) |
| 0.6 | 2.4 | GO:0015193 | L-proline transmembrane transporter activity(GO:0015193) |
| 0.4 | 2.4 | GO:0000400 | four-way junction DNA binding(GO:0000400) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 15.6 | PID NFAT TFPATHWAY | Calcineurin-regulated NFAT-dependent transcription in lymphocytes |
| 0.3 | 2.3 | PID FANCONI PATHWAY | Fanconi anemia pathway |
| 0.3 | 0.9 | PID IL4 2PATHWAY | IL4-mediated signaling events |
| 0.3 | 0.9 | SA G1 AND S PHASES | Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition. |
| 0.1 | 0.3 | PID ATR PATHWAY | ATR signaling pathway |
| 0.1 | 0.3 | PID MYC ACTIV PATHWAY | Validated targets of C-MYC transcriptional activation |
| 0.0 | 0.2 | PID P73PATHWAY | p73 transcription factor network |
| 0.0 | 0.2 | PID ERA GENOMIC PATHWAY | Validated nuclear estrogen receptor alpha network |
| 0.1 | 0.1 | PID CMYB PATHWAY | C-MYB transcription factor network |
| 0.0 | 0.1 | NABA ECM REGULATORS | Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 15.6 | REACTOME CHONDROITIN SULFATE BIOSYNTHESIS | Genes involved in Chondroitin sulfate biosynthesis |
| 0.3 | 2.8 | REACTOME GLUCONEOGENESIS | Genes involved in Gluconeogenesis |
| 0.9 | 2.6 | REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS | Genes involved in Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. |
| 0.4 | 1.3 | REACTOME MEIOTIC SYNAPSIS | Genes involved in Meiotic Synapsis |
| 0.1 | 1.2 | REACTOME MEIOTIC RECOMBINATION | Genes involved in Meiotic Recombination |
| 0.1 | 0.3 | REACTOME G1 S SPECIFIC TRANSCRIPTION | Genes involved in G1/S-Specific Transcription |
| 0.1 | 0.3 | REACTOME MRNA 3 END PROCESSING | Genes involved in mRNA 3'-end processing |
| 0.1 | 0.3 | REACTOME METABOLISM OF POLYAMINES | Genes involved in Metabolism of polyamines |
| 0.0 | 0.3 | REACTOME CHROMOSOME MAINTENANCE | Genes involved in Chromosome Maintenance |
| 0.1 | 0.2 | REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S | Genes involved in Activation of Chaperone Genes by XBP1(S) |