Gene Symbol | Gene ID | Gene Info |
---|---|---|
PDR1
|
S000002981 | Transcription factor that regulates the pleiotropic drug response |
Promoter | Log-likelihood | Transcript | Gene | Gene Info |
---|---|---|---|---|
YMR102C | 8.16 |
Protein of unknown function; transcription is activated by paralogous transcription factors Yrm1p and Yrr1p along with genes involved in multidrug resistance; mutant shows increased resistance to azoles; YMR102C is not an essential gene |
||
YJR094W-A | 7.76 |
RPL43B
|
Protein component of the large (60S) ribosomal subunit, identical to Rpl43Ap and has similarity to rat L37a ribosomal protein |
|
YOR153W | 7.74 |
PDR5
|
Plasma membrane ATP-binding cassette (ABC) transporter, short-lived multidrug transporter actively regulated by Pdr1p; also involved in steroid transport, cation resistance, and cellular detoxification during exponential growth |
|
YFR055W | 6.74 |
IRC7
|
Putative cystathionine beta-lyase; involved in copper ion homeostasis and sulfur metabolism; null mutant displays increased levels of spontaneous Rad52p foci; expression induced by nitrogen limitation in a GLN3, GAT1-dependent manner |
|
YER131W | 6.23 |
RPS26B
|
Protein component of the small (40S) ribosomal subunit; nearly identical to Rps26Ap and has similarity to rat S26 ribosomal protein |
|
YFR056C | 5.84 |
Dubious open reading frame unlikely to encode a protein based on available experimental and comparative sequence data; partially overlaps the uncharacterized gene YFR055W |
||
YDR345C | 5.52 |
HXT3
|
Low affinity glucose transporter of the major facilitator superfamily, expression is induced in low or high glucose conditions |
|
YGL209W | 5.01 |
MIG2
|
Protein containing zinc fingers, involved in repression, along with Mig1p, of SUC2 (invertase) expression by high levels of glucose; binds to Mig1p-binding sites in SUC2 promoter |
|
YPL250W-A | 5.00 |
Identified by fungal homology and RT-PCR |
||
YDR044W | 4.98 |
HEM13
|
Coproporphyrinogen III oxidase, an oxygen requiring enzyme that catalyzes the sixth step in the heme biosynthetic pathway; localizes to the mitochondrial inner membrane; transcription is repressed by oxygen and heme (via Rox1p and Hap1p) |
|
YGL157W | 4.96 |
Oxidoreductase, catalyzes NADPH-dependent reduction of the bicyclic diketone bicyclo[2.2.2]octane-2,6-dione (BCO2,6D) to the chiral ketoalcohol (1R,4S,6S)-6-hydroxybicyclo[2.2.2]octane-2-one (BCO2one6ol) |
||
YLR413W | 4.74 |
Putative protein of unknown function; YLR413W is not an essential gene |
||
YDR279W | 4.03 |
RNH202
|
Ribonuclease H2 subunit, required for RNase H2 activity |
|
YIL056W | 3.96 |
VHR1
|
Transcriptional activator, required for the vitamin H-responsive element (VHRE) mediated induction of VHT1 (Vitamin H transporter) and BIO5 (biotin biosynthesis intermediate transporter) in response to low biotin concentrations |
|
YGR108W | 3.10 |
CLB1
|
B-type cyclin involved in cell cycle progression; activates Cdc28p to promote the transition from G2 to M phase; accumulates during G2 and M, then targeted via a destruction box motif for ubiquitin-mediated degradation by the proteasome |
|
YNL231C | 3.08 |
PDR16
|
Phosphatidylinositol transfer protein (PITP) controlled by the multiple drug resistance regulator Pdr1p, localizes to lipid particles and microsomes, controls levels of various lipids, may regulate lipid synthesis, homologous to Pdr17p |
|
YNL178W | 3.02 |
RPS3
|
Protein component of the small (40S) ribosomal subunit, has apurinic/apyrimidinic (AP) endonuclease activity; essential for viability; has similarity to E. coli S3 and rat S3 ribosomal proteins |
|
YOR050C | 2.98 |
Hypothetical protein |
||
YJL158C | 2.95 |
CIS3
|
Mannose-containing glycoprotein constituent of the cell wall; member of the PIR (proteins with internal repeats) family |
|
YCL063W | 2.90 |
VAC17
|
Protein involved in vacuole inheritance; acts as a vacuole-specific receptor for myosin Myo2p |
|
YGR280C | 2.77 |
PXR1
|
Essential protein involved in rRNA and snoRNA maturation; competes with TLC1 RNA for binding to Est2p, suggesting a role in negative regulation of telomerase; human homolog inhibits telomerase; contains a G-patch RNA interacting domain |
|
YDR502C | 2.76 |
SAM2
|
S-adenosylmethionine synthetase, catalyzes transfer of the adenosyl group of ATP to the sulfur atom of methionine; one of two differentially regulated isozymes (Sam1p and Sam2p) |
|
YKR075C | 2.71 |
Protein of unknown function; similar to YOR062Cp and Reg1p; expression regulated by glucose and Rgt1p; GFP-fusion protein is induced in response to the DNA-damaging agent MMS |
||
YDR002W | 2.70 |
YRB1
|
Ran GTPase binding protein; involved in nuclear protein import and RNA export, ubiquitin-mediated protein degradation during the cell cycle; shuttles between the nucleus and cytoplasm; is essential; homolog of human RanBP1 |
|
YKR092C | 2.70 |
SRP40
|
Nucleolar, serine-rich protein with a role in preribosome assembly or transport; may function as a chaperone of small nucleolar ribonucleoprotein particles (snoRNPs); immunologically and structurally to rat Nopp140 |
|
YJL153C | 2.67 |
INO1
|
Inositol 1-phosphate synthase, involved in synthesis of inositol phosphates and inositol-containing phospholipids; transcription is coregulated with other phospholipid biosynthetic genes by Ino2p and Ino4p, which bind the UASINO DNA element |
|
YPL062W | 2.64 |
Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; YPL062W is not an essential gene; homozygous diploid mutant shows a decrease in glycogen accumulation |
||
YOR315W | 2.56 |
SFG1
|
Nuclear protein, putative transcription factor required for growth of superficial pseudohyphae (which do not invade the agar substrate) but not for invasive pseudohyphal growth; may act together with Phd1p; potential Cdc28p substrate |
|
YDR025W | 2.54 |
RPS11A
|
Protein component of the small (40S) ribosomal subunit; identical to Rps11Bp and has similarity to E. coli S17 and rat S11 ribosomal proteins |
|
YLR075W | 2.54 |
RPL10
|
Protein component of the large (60S) ribosomal subunit, responsible for joining the 40S and 60S subunits; regulates translation initiation; has similarity to rat L10 ribosomal protein and to members of the QM gene family |
|
YKL096W-A | 2.53 |
CWP2
|
Covalently linked cell wall mannoprotein, major constituent of the cell wall; plays a role in stabilizing the cell wall; involved in low pH resistance; precursor is GPI-anchored |
|
YGR249W | 2.51 |
MGA1
|
Protein similar to heat shock transcription factor; multicopy suppressor of pseudohyphal growth defects of ammonium permease mutants |
|
YOR369C | 2.44 |
RPS12
|
Protein component of the small (40S) ribosomal subunit; has similarity to rat ribosomal protein S12 |
|
YOR163W | 2.39 |
DDP1
|
Polyphosphate phosphatase; hydrolyzes diphosphorylated inositol polyphosphates and diadenosine polyphosphates; has high specificity for diadenosine hexa- and pentaphosphates; member of the MutT family of nucleotide hydrolases |
|
YPR148C | 2.36 |
Protein of unknown function that may interact with ribosomes, based on co-purification experiments; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern |
||
YER177W | 2.35 |
BMH1
|
14-3-3 protein, major isoform; controls proteome at post-transcriptional level, binds proteins and DNA, involved in regulation of many processes including exocytosis, vesicle transport, Ras/MAPK signaling, and rapamycin-sensitive signaling |
|
YHR136C | 2.27 |
SPL2
|
Protein with similarity to cyclin-dependent kinase inhibitors, overproduction suppresses a plc1 null mutation; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern |
|
YPR119W | 2.25 |
CLB2
|
B-type cyclin involved in cell cycle progression; activates Cdc28p to promote the transition from G2 to M phase; accumulates during G2 and M, then targeted via a destruction box motif for ubiquitin-mediated degradation by the proteasome |
|
YPR157W | 2.24 |
Putative protein of unknown function; induced by treatment with 8-methoxypsoralen and UVA irradiation |
||
YML026C | 2.21 |
RPS18B
|
Protein component of the small (40S) ribosomal subunit; nearly identical to Rps18Ap and has similarity to E. coli S13 and rat S18 ribosomal proteins |
|
YCL064C | 2.17 |
CHA1
|
Catabolic L-serine (L-threonine) deaminase, catalyzes the degradation of both L-serine and L-threonine; required to use serine or threonine as the sole nitrogen source, transcriptionally induced by serine and threonine |
|
YOR327C | 2.17 |
SNC2
|
Vesicle membrane receptor protein (v-SNARE) involved in the fusion between Golgi-derived secretory vesicles with the plasma membrane; member of the synaptobrevin/VAMP family of R-type v-SNARE proteins |
|
YER130C | 2.12 |
Hypothetical protein |
||
YGR052W | 2.04 |
FMP48
|
Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; induced by treatment with 8-methoxypsoralen and UVA irradiation |
|
YGR214W | 2.02 |
RPS0A
|
Protein component of the small (40S) ribosomal subunit, nearly identical to Rps0Bp; required for maturation of 18S rRNA along with Rps0Bp; deletion of either RPS0 gene reduces growth rate, deletion of both genes is lethal |
|
YHR128W | 1.99 |
FUR1
|
Uracil phosphoribosyltransferase, synthesizes UMP from uracil; involved in the pyrimidine salvage pathway |
|
YJR070C | 1.98 |
LIA1
|
Deoxyhypusine hydroxylase, a HEAT-repeat containing metalloenzyme that catalyses hypusine formation; binds to and is required for the modification of Hyp2p (eIF5A); complements S. pombe mmd1 mutants defective in mitochondrial positioning |
|
YIL118W | 1.95 |
RHO3
|
Non-essential small GTPase of the Rho/Rac subfamily of Ras-like proteins involved in the establishment of cell polarity; GTPase activity positively regulated by the GTPase activating protein (GAP) Rgd1p |
|
YJR071W | 1.89 |
Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data |
||
YBR143C | 1.81 |
SUP45
|
Polypeptide release factor involved in translation termination; mutant form acts as a recessive omnipotent suppressor |
|
YMR015C | 1.81 |
ERG5
|
C-22 sterol desaturase, a cytochrome P450 enzyme that catalyzes the formation of the C-22(23) double bond in the sterol side chain in ergosterol biosynthesis; may be a target of azole antifungal drugs |
|
YPL249C-A | 1.80 |
RPL36B
|
Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl36Ap and has similarity to rat L36 ribosomal protein; binds to 5.8 S rRNA |
|
YLR333C | 1.78 |
RPS25B
|
Protein component of the small (40S) ribosomal subunit; nearly identical to Rps25Ap and has similarity to rat S25 ribosomal protein |
|
YBR048W | 1.77 |
RPS11B
|
Protein component of the small (40S) ribosomal subunit; identical to Rps11Ap and has similarity to E. coli S17 and rat S11 ribosomal proteins |
|
YJR123W | 1.74 |
RPS5
|
Protein component of the small (40S) ribosomal subunit, the least basic of the non-acidic ribosomal proteins; phosphorylated in vivo; essential for viability; has similarity to E. coli S7 and rat S5 ribosomal proteins |
|
YOL124C | 1.73 |
TRM11
|
Catalytic subunit of an adoMet-dependent tRNA methyltransferase complex (Trm11p-Trm112p), required for the methylation of the guanosine nucleotide at position 10 (m2G10) in tRNAs; contains a THUMP domain and a methyltransferase domain |
|
YDL047W | 1.72 |
SIT4
|
Type 2A-related serine-threonine phosphatase that functions in the G1/S transition of the mitotic cycle; cytoplasmic and nuclear protein that modulates functions mediated by Pkc1p including cell wall and actin cytoskeleton organization |
|
YDL023C | 1.72 |
Dubious open reading frame, unlikely to encode a protein; not conserved in other Saccharomyces species; overlaps the verified gene GPD1; deletion confers sensitivity to GSAO; deletion in cyr1 mutant results in loss of stress resistance |
||
YGR050C | 1.71 |
Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data |
||
YHL028W | 1.68 |
WSC4
|
ER membrane protein involved in the translocation of soluble secretory proteins and insertion of membrane proteins into the ER membrane; may also have a role in the stress response but has only partial functional overlap with WSC1-3 |
|
YLR448W | 1.66 |
RPL6B
|
Protein component of the large (60S) ribosomal subunit, has similarity to Rpl6Ap and to rat L6 ribosomal protein; binds to 5.8S rRNA |
|
YDR072C | 1.66 |
IPT1
|
Inositolphosphotransferase 1, involved in synthesis of mannose-(inositol-P)2-ceramide (M(IP)2C), which is the most abundant sphingolipid in cells, mutation confers resistance to the antifungals syringomycin E and DmAMP1 in some growth media |
|
YBR257W | 1.64 |
POP4
|
Subunit of both RNase MRP, which cleaves pre-rRNA, and nuclear RNase P, which cleaves tRNA precursors to generate mature 5' ends; binds to the RPR1 RNA subunit in Rnase P |
|
YER137C | 1.63 |
Putative protein of unknown function |
||
YLL028W | 1.63 |
TPO1
|
Polyamine transporter that recognizes spermine, putrescine, and spermidine; catalyzes uptake of polyamines at alkaline pH and excretion at acidic pH; phosphorylation enhances activity and sorting to the plasma membrane |
|
YLR349W | 1.62 |
Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; overlaps the verified ORF DIC1/YLR348C |
||
YIR021W | 1.61 |
MRS1
|
Protein required for the splicing of two mitochondrial group I introns (BI3 in COB and AI5beta in COX1); forms a splicing complex, containing four subunits of Mrs1p and two subunits of the BI3-encoded maturase, that binds to the BI3 RNA |
|
YGL179C | 1.56 |
TOS3
|
Protein kinase, related to and functionally redundant with Elm1p and Sak1p for the phosphorylation and activation of Snf1p; functionally orthologous to LKB1, a mammalian kinase associated with Peutz-Jeghers cancer-susceptibility syndrome |
|
YLR348C | 1.55 |
DIC1
|
Mitochondrial dicarboxylate carrier, integral membrane protein, catalyzes a dicarboxylate-phosphate exchange across the inner mitochondrial membrane, transports cytoplasmic dicarboxylates into the mitochondrial matrix |
|
YBL085W | 1.52 |
BOI1
|
Protein implicated in polar growth, functionally redundant with Boi2p; interacts with bud-emergence protein Bem1p; contains an SH3 (src homology 3) domain and a PH (pleckstrin homology) domain |
|
YBL063W | 1.52 |
KIP1
|
Kinesin-related motor protein required for mitotic spindle assembly and chromosome segregation; functionally redundant with Cin8p |
|
YDR033W | 1.51 |
MRH1
|
Protein that localizes primarily to the plasma membrane, also found at the nuclear envelope; the authentic, non-tagged protein is detected in mitochondria in a phosphorylated state; has similarity to Hsp30p and Yro2p |
|
YDL022W | 1.48 |
GPD1
|
NAD-dependent glycerol-3-phosphate dehydrogenase, key enzyme of glycerol synthesis, essential for growth under osmotic stress; expression regulated by high-osmolarity glycerol response pathway; homolog of Gpd2p |
|
YCR004C | 1.48 |
YCP4
|
Protein of unknown function, has sequence and structural similarity to flavodoxins; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies |
|
YHR021C | 1.47 |
RPS27B
|
Protein component of the small (40S) ribosomal subunit; nearly identical to Rps27Ap and has similarity to rat S27 ribosomal protein |
|
YMR290W-A | 1.43 |
Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data; overlaps 5' end of essential HAS1 gene which encodes an ATP-dependent RNA helicase |
||
YLR154C | 1.43 |
RNH203
|
Ribonuclease H2 subunit, required for RNase H2 activity |
|
YLR301W | 1.42 |
Protein of unknown function that interacts with Sec72p |
||
YPL239W | 1.42 |
YAR1
|
Cytoplasmic ankyrin-repeat containing protein of unknown function, proposed to link the processes of 40S ribosomal subunit biogenesis and adaptation to osmotic and oxidative stress; expression repressed by heat shock |
|
YGR051C | 1.40 |
Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; YGR051C is not an essential gene |
||
YLR314C | 1.40 |
CDC3
|
Component of the septin ring of the mother-bud neck that is required for cytokinesis; septins recruit proteins to the neck and can act as a barrier to diffusion at the membrane, and they comprise the 10nm filaments seen with EM |
|
YIL133C | 1.40 |
RPL16A
|
N-terminally acetylated protein component of the large (60S) ribosomal subunit, binds to 5.8 S rRNA; has similarity to Rpl16Bp, E. coli L13 and rat L13a ribosomal proteins; transcriptionally regulated by Rap1p |
|
YMR290C | 1.39 |
HAS1
|
ATP-dependent RNA helicase; localizes to both the nuclear periphery and nucleolus; highly enriched in nuclear pore complex fractions; constituent of 66S pre-ribosomal particles |
|
YDR381W | 1.37 |
YRA1
|
Nuclear protein that binds to RNA and to Mex67p, required for export of poly(A)+ mRNA from the nucleus; member of the REF (RNA and export factor binding proteins) family; another family member, Yra2p, can substitute for Yra1p function |
|
YMR246W | 1.37 |
FAA4
|
Long chain fatty acyl-CoA synthetase, regulates protein modification during growth in the presence of ethanol, functions to incorporate palmitic acid into phospholipids and neutral lipids |
|
YMR266W | 1.36 |
RSN1
|
Membrane protein of unknown function; overexpression suppresses NaCl sensitivity of sro7 mutant |
|
YDR278C | 1.33 |
Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data |
||
YDL211C | 1.33 |
Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the vacuole |
||
YOL123W | 1.32 |
HRP1
|
Subunit of cleavage factor I, a five-subunit complex required for the cleavage and polyadenylation of pre-mRNA 3' ends; RRM-containing heteronuclear RNA binding protein and hnRNPA/B family member that binds to poly (A) signal sequences |
|
YHR137W | 1.31 |
ARO9
|
Aromatic aminotransferase II, catalyzes the first step of tryptophan, phenylalanine, and tyrosine catabolism |
|
YBR256C | 1.30 |
RIB5
|
Riboflavin synthase; catalyzes the last step of the riboflavin biosynthesis pathway |
|
YIL011W | 1.30 |
TIR3
|
Cell wall mannoprotein of the Srp1p/Tip1p family of serine-alanine-rich proteins; expressed under anaerobic conditions and required for anaerobic growth |
|
YDL143W | 1.30 |
CCT4
|
Subunit of the cytosolic chaperonin Cct ring complex, related to Tcp1p, required for the assembly of actin and tubulins in vivo |
|
YHR010W | 1.30 |
RPL27A
|
Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl27Bp and has similarity to rat L27 ribosomal protein |
|
YGR264C | 1.30 |
MES1
|
Methionyl-tRNA synthetase, forms a complex with glutamyl-tRNA synthetase (Gus1p) and Arc1p, which increases the catalytic efficiency of both tRNA synthetases; also has a role in nuclear export of tRNAs |
|
YGR251W | 1.29 |
Putative protein of unknown function; deletion mutant has defects in pre-rRNA processing; green fluorescent protein (GFP)-fusion protein localizes to both the nucleus and the nucleolus; YGR251W is an essential gene |
||
YMR083W | 1.29 |
ADH3
|
Mitochondrial alcohol dehydrogenase isozyme III; involved in the shuttling of mitochondrial NADH to the cytosol under anaerobic conditions and ethanol production |
|
YKL218C | 1.28 |
SRY1
|
3-hydroxyaspartate dehydratase, deaminates L-threo-3-hydroxyaspartate to form oxaloacetate and ammonia; required for survival in the presence of hydroxyaspartate |
|
YAL003W | 1.28 |
EFB1
|
Translation elongation factor 1 beta; stimulates nucleotide exchange to regenerate EF-1 alpha-GTP for the next elongation cycle; part of the EF-1 complex, which facilitates binding of aminoacyl-tRNA to the ribosomal A site |
|
YJR094C | 1.27 |
IME1
|
Master regulator of meiosis that is active only during meiotic events, activates transcription of early meiotic genes through interaction with Ume6p, degraded by the 26S proteasome following phosphorylation by Ime2p |
|
YOR108W | 1.27 |
LEU9
|
Alpha-isopropylmalate synthase II (2-isopropylmalate synthase), catalyzes the first step in the leucine biosynthesis pathway; the minor isozyme, responsible for the residual alpha-IPMS activity detected in a leu4 null mutant |
|
YJL148W | 1.27 |
RPA34
|
RNA polymerase I subunit A34.5 |
|
YJL200C | 1.27 |
ACO2
|
Putative mitochondrial aconitase isozyme; similarity to Aco1p, an aconitase required for the TCA cycle; expression induced during growth on glucose, by amino acid starvation via Gcn4p, and repressed on ethanol |
|
YMR009W | 1.26 |
ADI1
|
Acireductone dioxygenease involved in the methionine salvage pathway; ortholog of human MTCBP-1; transcribed with YMR010W and regulated post-transcriptionally by RNase III (Rnt1p) cleavage; ADI1 mRNA is induced in heat shock conditions |
|
YPL137C | 1.26 |
GIP3
|
Glc7-interacting protein whose overexpression relocalizes Glc7p from the nucleus and prevents chromosome segregation; may interact with ribosomes, based on co-purification experiments |
|
YPL177C | 1.25 |
CUP9
|
Homeodomain-containing transcriptional repressor of PTR2, which encodes a major peptide transporter; imported peptides activate ubiquitin-dependent proteolysis, resulting in degradation of Cup9p and de-repression of PTR2 transcription |
|
YGR265W | 1.25 |
Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified ORF MES1/YGR264C, which encodes methionyl-tRNA synthetase |
||
YMR208W | 1.24 |
ERG12
|
Mevalonate kinase, acts in the biosynthesis of isoprenoids and sterols, including ergosterol, from mevalonate |
|
YML075C | 1.24 |
HMG1
|
One of two isozymes of HMG-CoA reductase that catalyzes the conversion of HMG-CoA to mevalonate, which is a rate-limiting step in sterol biosynthesis; localizes to the nuclear envelope; overproduction induces the formation of karmellae |
|
YLR154W-A | 1.24 |
Dubious open reading frame unlikely to encode a protein; encoded within the the 25S rRNA gene on the opposite strand |
||
YLR441C | 1.23 |
RPS1A
|
Ribosomal protein 10 (rp10) of the small (40S) subunit; nearly identical to Rps1Bp and has similarity to rat S3a ribosomal protein |
|
YLR154W-B | 1.22 |
Dubious open reading frame unlikely to encode a protein; encoded within the the 25S rRNA gene on the opposite strand |
||
YHR013C | 1.22 |
ARD1
|
Subunit of the N-terminal acetyltransferase NatA (Nat1p, Ard1p, Nat5p); N-terminally acetylates many proteins, which influences multiple processes such as the cell cycle, heat-shock resistance, mating, sporulation, and telomeric silencing |
|
YLR099W-A | 1.22 |
Putative protein of unknown function |
||
YDR073W | 1.21 |
SNF11
|
Subunit of the SWI/SNF chromatin remodeling complex involved in transcriptional regulation; interacts with a highly conserved 40-residue sequence of Snf2p |
|
YGR034W | 1.20 |
RPL26B
|
Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl26Ap and has similarity to E. coli L24 and rat L26 ribosomal proteins; binds to 5.8S rRNA |
|
YNR013C | 1.20 |
PHO91
|
Low-affinity phosphate transporter of the vacuolar membrane; deletion of pho84, pho87, pho89, pho90, and pho91 causes synthetic lethality; transcription independent of Pi and Pho4p activity; overexpression results in vigorous growth |
|
YKL110C | 1.19 |
KTI12
|
Protein that plays a role, with Elongator complex, in modification of wobble nucleosides in tRNA; involved in sensitivity to G1 arrest induced by zymocin; interacts with chromatin throughout the genome; also interacts with Cdc19p |
|
YJR043C | 1.17 |
POL32
|
Third subunit of DNA polymerase delta, involved in chromosomal DNA replication; required for error-prone DNA synthesis in the presence of DNA damage and processivity; interacts with Hys2p, PCNA (Pol30p), and Pol1p |
|
YPR074C | 1.16 |
TKL1
|
Transketolase, similar to Tkl2p; catalyzes conversion of xylulose-5-phosphate and ribose-5-phosphate to sedoheptulose-7-phosphate and glyceraldehyde-3-phosphate in the pentose phosphate pathway; needed for synthesis of aromatic amino acids |
|
YDR041W | 1.15 |
RSM10
|
Mitochondrial ribosomal protein of the small subunit, has similarity to E. coli S10 ribosomal protein; essential for viability, unlike most other mitoribosomal proteins |
|
YJL011C | 1.15 |
RPC17
|
RNA polymerase III subunit C17; physically interacts with C31, C11, and TFIIIB70; may be involved in the recruitment of pol III by the preinitiation complex |
|
YPR014C | 1.14 |
Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; YPR014C is not an essential gene |
||
YIL148W | 1.12 |
RPL40A
|
Fusion protein, identical to Rpl40Bp, that is cleaved to yield ubiquitin and a ribosomal protein of the large (60S) ribosomal subunit with similarity to rat L40; ubiquitin may facilitate assembly of the ribosomal protein into ribosomes |
|
YMR006C | 1.12 |
PLB2
|
Phospholipase B (lysophospholipase) involved in phospholipid metabolism; displays transacylase activity in vitro; overproduction confers resistance to lysophosphatidylcholine |
|
YOR025W | 1.11 |
HST3
|
Member of the Sir2 family of NAD(+)-dependent protein deacetylases; involved along with Hst4p in telomeric silencing, cell cycle progression, radiation resistance, genomic stability and short-chain fatty acid metabolism |
|
YNL289W | 1.11 |
PCL1
|
Pho85 cyclin of the Pcl1,2-like subfamily, involved in entry into the mitotic cell cycle and regulation of morphogenesis, localizes to sites of polarized cell growth |
|
YKL165C | 1.10 |
MCD4
|
Protein involved in glycosylphosphatidylinositol (GPI) anchor synthesis; multimembrane-spanning protein that localizes to the endoplasmic reticulum; highly conserved among eukaryotes |
|
YHR068W | 1.10 |
DYS1
|
Deoxyhypusine synthase, catalyzes formation of deoxyhypusine, the first step in hypusine biosynthesis; triggers posttranslational hypusination of translation elongation factor eIF-5A and regulates its intracellular levels; tetrameric |
|
YDR091C | 1.09 |
RLI1
|
Essential iron-sulfur protein required for ribosome biogenesis and translation initiation; facilitates binding of a multifactor complex (MFC) of translation initiation factors to the small ribosomal subunit; predicted ABC family ATPase |
|
YKL052C | 1.09 |
ASK1
|
Essential subunit of the Dam1 complex (aka DASH complex), couples kinetochores to the force produced by MT depolymerization thereby aiding in chromosome segregation; phosphorylated during the cell cycle by cyclin-dependent kinases |
|
YFL015C | 1.07 |
Dubious open reading frame unlikely to encode a protein; partially overlaps dubious ORF YFL015W-A; YFL015C is not an essential gene |
||
YFR054C | 1.06 |
Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data |
||
YOL012C | 1.06 |
HTZ1
|
Histone variant H2AZ, exchanged for histone H2A in nucleosomes by the SWR1 complex; involved in transcriptional regulation through prevention of the spread of silent heterochromatin |
|
YNL301C | 1.06 |
RPL18B
|
Protein component of the large (60S) ribosomal subunit, identical to Rpl18Ap and has similarity to rat L18 ribosomal protein |
|
YGR253C | 1.05 |
PUP2
|
Alpha 5 subunit of the 20S proteasome involved in ubiquitin-dependent catabolism; human homolog is subunit zeta |
|
YOL101C | 1.04 |
IZH4
|
Membrane protein involved in zinc metabolism, member of the four-protein IZH family, expression induced by fatty acids and altered zinc levels; deletion reduces sensitivity to excess zinc; possible role in sterol metabolism |
|
YLR367W | 1.04 |
RPS22B
|
Protein component of the small (40S) ribosomal subunit; nearly identical to Rps22Ap and has similarity to E. coli S8 and rat S15a ribosomal proteins |
|
YDR534C | 1.03 |
FIT1
|
Mannoprotein that is incorporated into the cell wall via a glycosylphosphatidylinositol (GPI) anchor, involved in the retention of siderophore-iron in the cell wall |
|
YKL180W | 1.03 |
RPL17A
|
Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl17Bp and has similarity to E. coli L22 and rat L17 ribosomal proteins; copurifies with the Dam1 complex (aka DASH complex) |
|
YLR300W | 1.02 |
EXG1
|
Major exo-1,3-beta-glucanase of the cell wall, involved in cell wall beta-glucan assembly; exists as three differentially glycosylated isoenzymes |
|
YBL006C | 1.02 |
LDB7
|
Component of the RSC chromatin remodeling complex; interacts with Rsc3p, Rsc30p, Npl6p, and Htl1p to form a module important for a broad range of RSC functions |
|
YFL015W-A | 1.01 |
Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data |
||
YBR159W | 1.01 |
IFA38
|
Microsomal beta-keto-reductase; contains oleate response element (ORE) sequence in the promoter region; mutants exhibit reduced VLCFA synthesis, accumulate high levels of dihydrosphingosine, phytosphingosine and medium-chain ceramides |
|
YAL053W | 1.01 |
FLC2
|
Putative FAD transporter; required for uptake of FAD into endoplasmic reticulum; involved in cell wall maintenance |
|
YLR355C | 1.00 |
ILV5
|
Acetohydroxyacid reductoisomerase, mitochondrial protein involved in branched-chain amino acid biosynthesis, also required for maintenance of wild-type mitochondrial DNA and found in mitochondrial nucleoids |
|
YLR312W-A | 0.99 |
MRPL15
|
Mitochondrial ribosomal protein of the large subunit |
|
YHR216W | 0.99 |
IMD2
|
Inosine monophosphate dehydrogenase, catalyzes the first step of GMP biosynthesis, expression is induced by mycophenolic acid resulting in resistance to the drug, expression is repressed by nutrient limitation |
|
YBR210W | 0.99 |
ERV15
|
Protein involved in export of proteins from the endoplasmic reticulum, has similarity to Erv14p |
|
YDR098C | 0.99 |
GRX3
|
Hydroperoxide and superoxide-radical responsive glutathione-dependent oxidoreductase; monothiol glutaredoxin subfamily member along with Grx4p and Grx5p; protects cells from oxidative damage |
|
YPL112C | 0.97 |
PEX25
|
Peripheral peroxisomal membrane peroxin required for the regulation of peroxisome size and maintenance, recruits GTPase Rho1p to peroxisomes, induced by oleate, interacts with homologous protein Pex27p |
|
YGR121W-A | 0.97 |
Putative protein of unknown function |
||
YKR074W | 0.97 |
AIM29
|
Putative protein of unknown function; epitope-tagged protein localizes to the cytoplasm; null mutant displays increased frequency of mitochondrial genome loss (petite formation) |
|
YDL022C-A | 0.96 |
Dubious open reading frame unlikely to encode a protein; partially overlaps the verified gene DIA3; identified by fungal homology and RT-PCR |
||
YGR128C | 0.96 |
UTP8
|
Nucleolar protein required for export of tRNAs from the nucleus; also copurifies with the small subunit (SSU) processome containing the U3 snoRNA that is involved in processing of pre-18S rRNA |
|
YHR149C | 0.96 |
SKG6
|
Integral membrane protein that localizes primarily to growing sites such as the bud tip or the cell periphery; potential Cdc28p substrate; Skg6p interacts with Zds1p and Zds2p |
|
YGR242W | 0.96 |
Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified ORF YAP1802/YGR241C |
||
YKR093W | 0.95 |
PTR2
|
Integral membrane peptide transporter, mediates transport of di- and tri-peptides; conserved protein that contains 12 transmembrane domains; PTR2 expression is regulated by the N-end rule pathway via repression by Cup9p |
|
YDR040C | 0.95 |
ENA1
|
P-type ATPase sodium pump, involved in Na+ and Li+ efflux to allow salt tolerance |
|
YDR133C | 0.94 |
Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps YDR134C |
||
YJL162C | 0.93 |
JJJ2
|
Protein of unknown function, contains a J-domain, which is a region with homology to the E. coli DnaJ protein |
|
YDR509W | 0.92 |
Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data |
||
YMR108W | 0.92 |
ILV2
|
Acetolactate synthase, catalyses the first common step in isoleucine and valine biosynthesis and is the target of several classes of inhibitors, localizes to the mitochondria; expression of the gene is under general amino acid control |
|
YDR074W | 0.92 |
TPS2
|
Phosphatase subunit of the trehalose-6-phosphate synthase/phosphatase complex, which synthesizes the storage carbohydrate trehalose; expression is induced by stress conditions and repressed by the Ras-cAMP pathway |
|
YDR508C | 0.92 |
GNP1
|
High-affinity glutamine permease, also transports Leu, Ser, Thr, Cys, Met and Asn; expression is fully dependent on Grr1p and modulated by the Ssy1p-Ptr3p-Ssy5p (SPS) sensor of extracellular amino acids |
|
YMR033W | 0.91 |
ARP9
|
Component of both the SWI/SNF and RSC chromatin remodeling complexes; actin-related protein involved in transcriptional regulation |
|
YJL115W | 0.91 |
ASF1
|
Nucleosome assembly factor, involved in chromatin assembly and disassembly, anti-silencing protein that causes derepression of silent loci when overexpressed; plays a role in regulating Ty1 transposition |
|
YML043C | 0.91 |
RRN11
|
Protein required for rDNA transcription by RNA polymerase I, component of the core factor (CF) of rDNA transcription factor, which also contains Rrn6p and Rrn7p |
|
YOL011W | 0.90 |
PLB3
|
Phospholipase B (lysophospholipase) involved in phospholipid metabolism; hydrolyzes phosphatidylinositol and phosphatidylserine and displays transacylase activity in vitro |
|
YER036C | 0.89 |
ARB1
|
ATPase of the ATP-binding cassette (ABC) family involved in 40S and 60S ribosome biogenesis, has similarity to Gcn20p; shuttles from nucleus to cytoplasm, physically interacts with Tif6p, Lsg1p |
|
YKL068W-A | 0.89 |
Putative protein of unknown function; identified by homology to Ashbya gossypii |
||
YKL051W | 0.88 |
SFK1
|
Plasma membrane protein that may act together with or upstream of Stt4p to generate normal levels of the essential phospholipid PI4P, at least partially mediates proper localization of Stt4p to the plasma membrane |
|
YNL175C | 0.87 |
NOP13
|
Protein of unknown function, localizes to the nucleolus and nucleoplasm; contains an RNA recognition motif (RRM) and has similarity to Nop12p, which is required for processing of pre-18S rRNA |
|
YHR081W | 0.87 |
LRP1
|
Substrate-specific nuclear cofactor for exosome activity in the processing of stable RNAs; required for telomere length maintenance; homolog of mammalian nuclear matrix protein C1D involved in regulation of DNA repair and recombination |
|
YKL120W | 0.86 |
OAC1
|
Mitochondrial inner membrane transporter, transports oxaloacetate, sulfate, and thiosulfate; member of the mitochondrial carrier family |
|
YDL048C | 0.86 |
STP4
|
Protein containing a Kruppel-type zinc-finger domain; has similarity to Stp1p, Stp2p, and Stp3p |
|
YGR241C | 0.86 |
YAP1802
|
Protein involved in clathrin cage assembly; binds Pan1p and clathrin; homologous to Yap1801p, member of the AP180 protein family |
|
YGR180C | 0.86 |
RNR4
|
Ribonucleotide-diphosphate reductase (RNR), small subunit; the RNR complex catalyzes the rate-limiting step in dNTP synthesis and is regulated by DNA replication and DNA damage checkpoint pathways via localization of the small subunits |
|
YBL092W | 0.85 |
RPL32
|
Protein component of the large (60S) ribosomal subunit, has similarity to rat L32 ribosomal protein; overexpression disrupts telomeric silencing |
|
YLR048W | 0.84 |
RPS0B
|
Protein component of the small (40S) ribosomal subunit, nearly identical to Rps0Ap; required for maturation of 18S rRNA along with Rps0Ap; deletion of either RPS0 gene reduces growth rate, deletion of both genes is lethal |
|
YOR008C-A | 0.84 |
Putative protein of unknown function, includes a potential transmembrane domain; deletion results in slightly lengthened telomeres |
||
YIL164C | 0.84 |
NIT1
|
Nitrilase, member of the nitrilase branch of the nitrilase superfamily; in closely related species and other S. cerevisiae strain backgrounds YIL164C and adjacent ORF, YIL165C, likely constitute a single ORF encoding a nitrilase gene |
|
YHR071C-A | 0.83 |
Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified ORF ERG7/YHR072W |
||
YCL024W | 0.83 |
KCC4
|
Protein kinase of the bud neck involved in the septin checkpoint, associates with septin proteins, negatively regulates Swe1p by phosphorylation, shows structural homology to bud neck kinases Gin4p and Hsl1p |
|
YKL181W | 0.83 |
PRS1
|
5-phospho-ribosyl-1(alpha)-pyrophosphate synthetase, synthesizes PRPP, which is required for nucleotide, histidine, and tryptophan biosynthesis; one of five related enzymes, which are active as heteromultimeric complexes |
|
YIL076W | 0.83 |
SEC28
|
Epsilon-COP subunit of the coatomer; regulates retrograde Golgi-to-ER protein traffic; stabilizes Cop1p, the alpha-COP and the coatomer complex; non-essential for cell growth |
|
YOR313C | 0.83 |
SPS4
|
Protein whose expression is induced during sporulation; not required for sporulation; heterologous expression in E. coli induces the SOS response that senses DNA damage |
|
YJL198W | 0.83 |
PHO90
|
Low-affinity phosphate transporter; deletion of pho84, pho87, pho89, pho90, and pho91 causes synthetic lethality; transcription independent of Pi and Pho4p activity; overexpression results in vigorous growth |
|
YER120W | 0.82 |
SCS2
|
Integral ER membrane protein that regulates phospholipid metabolism via an interaction with the FFAT motif of Opi1p, also involved in telomeric silencing, disruption causes inositol auxotrophy above 34 degrees C, VAP homolog |
|
YER074W | 0.80 |
RPS24A
|
Protein component of the small (40S) ribosomal subunit; identical to Rps24Bp and has similarity to rat S24 ribosomal protein |
|
YOR385W | 0.79 |
Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; YOR385W is not an essential gene |
||
YMR001C | 0.79 |
CDC5
|
Polo-like kinase with similarity to Xenopus Plx1 and S. pombe Plo1p; found at bud neck, nucleus and SPBs; has multiple functions in mitosis and cytokinesis through phosphorylation of substrates; may be a Cdc28p substrate |
|
YER012W | 0.79 |
PRE1
|
Beta 4 subunit of the 20S proteasome; localizes to the nucleus throughout the cell cycle |
|
YDR500C | 0.79 |
RPL37B
|
Protein component of the large (60S) ribosomal subunit, has similarity to Rpl37Ap and to rat L37 ribosomal protein |
|
YGL009C | 0.78 |
LEU1
|
Isopropylmalate isomerase, catalyzes the second step in the leucine biosynthesis pathway |
|
YBR106W | 0.78 |
PHO88
|
Probable membrane protein, involved in phosphate transport; pho88 pho86 double null mutant exhibits enhanced synthesis of repressible acid phosphatase at high inorganic phosphate concentrations |
|
YDR274C | 0.78 |
Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data |
||
YOR051C | 0.78 |
Nuclear protein that inhibits replication of Brome mosaic virus in S. cerevisiae, which is a model system for studying replication of positive-strand RNA viruses in their natural hosts |
||
YGR017W | 0.78 |
Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to both the nucleus and the cytoplasm |
||
YIL021W | 0.77 |
RPB3
|
RNA polymerase II third largest subunit B44, part of central core; similar to prokaryotic alpha subunit |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
2.2 | 8.8 | GO:0014070 | response to organic cyclic compound(GO:0014070) response to cycloheximide(GO:0046898) |
2.1 | 6.3 | GO:0000098 | sulfur amino acid catabolic process(GO:0000098) |
1.4 | 5.8 | GO:1900434 | filamentous growth of a population of unicellular organisms in response to starvation(GO:0036170) regulation of filamentous growth of a population of unicellular organisms in response to starvation(GO:1900434) positive regulation of filamentous growth of a population of unicellular organisms in response to starvation(GO:1900436) |
1.0 | 18.1 | GO:0051029 | rRNA export from nucleus(GO:0006407) rRNA transport(GO:0051029) |
0.9 | 6.6 | GO:0043137 | DNA replication, removal of RNA primer(GO:0043137) |
0.9 | 6.0 | GO:0010696 | positive regulation of spindle pole body separation(GO:0010696) |
0.8 | 3.2 | GO:0008612 | peptidyl-lysine modification to peptidyl-hypusine(GO:0008612) |
0.8 | 3.2 | GO:0000296 | spermine transport(GO:0000296) |
0.8 | 2.3 | GO:0051439 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle(GO:0051436) regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle(GO:0051439) negative regulation of ubiquitin protein ligase activity(GO:1904667) |
0.8 | 3.0 | GO:0046500 | S-adenosylmethionine metabolic process(GO:0046500) |
0.7 | 2.9 | GO:1904357 | negative regulation of telomere maintenance via telomerase(GO:0032211) negative regulation of telomere maintenance via telomere lengthening(GO:1904357) |
0.7 | 2.1 | GO:0006798 | polyphosphate catabolic process(GO:0006798) |
0.7 | 5.0 | GO:0006782 | protoporphyrinogen IX biosynthetic process(GO:0006782) protoporphyrinogen IX metabolic process(GO:0046501) |
0.7 | 2.1 | GO:0006567 | threonine catabolic process(GO:0006567) |
0.6 | 2.5 | GO:0046490 | isopentenyl diphosphate biosynthetic process(GO:0009240) isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287) isopentenyl diphosphate metabolic process(GO:0046490) |
0.6 | 0.6 | GO:0045901 | positive regulation of translational elongation(GO:0045901) |
0.5 | 2.1 | GO:0010138 | pyrimidine ribonucleotide salvage(GO:0010138) pyrimidine nucleotide salvage(GO:0032262) pyrimidine nucleoside salvage(GO:0043097) UMP salvage(GO:0044206) |
0.5 | 1.5 | GO:0030541 | plasmid partitioning(GO:0030541) |
0.5 | 1.5 | GO:2000877 | regulation of oligopeptide transport by regulation of transcription from RNA polymerase II promoter(GO:0035950) negative regulation of oligopeptide transport by negative regulation of transcription from RNA polymerase II promoter(GO:0035952) regulation of dipeptide transport by regulation of transcription from RNA polymerase II promoter(GO:0035953) negative regulation of dipeptide transport by negative regulation of transcription from RNA polymerase II promoter(GO:0035955) negative regulation of oligopeptide transport(GO:2000877) negative regulation of dipeptide transport(GO:2000879) |
0.5 | 2.0 | GO:0090338 | regulation of formin-nucleated actin cable assembly(GO:0090337) positive regulation of formin-nucleated actin cable assembly(GO:0090338) |
0.5 | 1.9 | GO:0035337 | fatty-acyl-CoA metabolic process(GO:0035337) |
0.5 | 1.4 | GO:0009186 | deoxyribonucleoside diphosphate metabolic process(GO:0009186) |
0.5 | 6.5 | GO:0000028 | ribosomal small subunit assembly(GO:0000028) |
0.4 | 2.1 | GO:0009098 | leucine biosynthetic process(GO:0009098) |
0.4 | 5.4 | GO:0006415 | translational termination(GO:0006415) |
0.4 | 4.3 | GO:0006817 | phosphate ion transport(GO:0006817) |
0.4 | 3.5 | GO:0042219 | cellular modified amino acid catabolic process(GO:0042219) |
0.4 | 1.5 | GO:0006072 | glycerol-3-phosphate metabolic process(GO:0006072) |
0.4 | 2.1 | GO:0006021 | inositol biosynthetic process(GO:0006021) |
0.3 | 1.0 | GO:0019673 | GDP-mannose biosynthetic process(GO:0009298) GDP-mannose metabolic process(GO:0019673) |
0.3 | 1.0 | GO:0042992 | negative regulation of transcription factor import into nucleus(GO:0042992) |
0.3 | 0.6 | GO:0033262 | regulation of nuclear cell cycle DNA replication(GO:0033262) |
0.3 | 0.8 | GO:0008272 | sulfate transport(GO:0008272) |
0.3 | 1.4 | GO:0032878 | regulation of establishment or maintenance of cell polarity(GO:0032878) |
0.3 | 0.3 | GO:0031120 | snRNA pseudouridine synthesis(GO:0031120) snRNA modification(GO:0040031) |
0.3 | 1.1 | GO:0015867 | ATP transport(GO:0015867) |
0.3 | 1.6 | GO:0009099 | valine biosynthetic process(GO:0009099) |
0.3 | 1.3 | GO:0043102 | L-methionine biosynthetic process from methylthioadenosine(GO:0019509) amino acid salvage(GO:0043102) L-methionine salvage(GO:0071267) |
0.3 | 33.9 | GO:0002181 | cytoplasmic translation(GO:0002181) |
0.3 | 1.1 | GO:0015883 | FAD transport(GO:0015883) |
0.3 | 2.6 | GO:0000056 | ribosomal small subunit export from nucleus(GO:0000056) |
0.3 | 1.3 | GO:0006177 | GMP biosynthetic process(GO:0006177) |
0.3 | 1.0 | GO:0030497 | fatty acid elongation(GO:0030497) |
0.3 | 0.8 | GO:0006654 | phosphatidic acid biosynthetic process(GO:0006654) phosphatidic acid metabolic process(GO:0046473) |
0.2 | 1.0 | GO:0042938 | dipeptide transport(GO:0042938) |
0.2 | 3.2 | GO:0000921 | septin ring assembly(GO:0000921) |
0.2 | 0.7 | GO:0019401 | glycerol biosynthetic process(GO:0006114) alditol biosynthetic process(GO:0019401) |
0.2 | 0.5 | GO:0019408 | polyprenol metabolic process(GO:0016093) polyprenol biosynthetic process(GO:0016094) dolichol metabolic process(GO:0019348) dolichol biosynthetic process(GO:0019408) |
0.2 | 2.5 | GO:0007109 | obsolete cytokinesis, completion of separation(GO:0007109) |
0.2 | 0.9 | GO:0006361 | transcription initiation from RNA polymerase I promoter(GO:0006361) |
0.2 | 0.7 | GO:0061422 | positive regulation of transcription from RNA polymerase II promoter in response to alkaline pH(GO:0061422) |
0.2 | 0.5 | GO:0001676 | long-chain fatty acid metabolic process(GO:0001676) |
0.2 | 1.1 | GO:0034723 | DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723) |
0.2 | 3.0 | GO:0010499 | proteasomal ubiquitin-independent protein catabolic process(GO:0010499) |
0.2 | 0.4 | GO:0061418 | regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061418) |
0.2 | 1.0 | GO:0046417 | chorismate metabolic process(GO:0046417) |
0.2 | 1.0 | GO:0046219 | tryptophan biosynthetic process(GO:0000162) indole-containing compound biosynthetic process(GO:0042435) indolalkylamine biosynthetic process(GO:0046219) |
0.2 | 2.0 | GO:0006547 | histidine biosynthetic process(GO:0000105) histidine metabolic process(GO:0006547) imidazole-containing compound metabolic process(GO:0052803) |
0.2 | 0.8 | GO:0048017 | inositol lipid-mediated signaling(GO:0048017) |
0.2 | 1.8 | GO:0006474 | N-terminal protein amino acid acetylation(GO:0006474) |
0.2 | 0.6 | GO:0006432 | phenylalanyl-tRNA aminoacylation(GO:0006432) |
0.2 | 3.5 | GO:0006334 | nucleosome assembly(GO:0006334) |
0.2 | 6.6 | GO:0016126 | steroid biosynthetic process(GO:0006694) sterol biosynthetic process(GO:0016126) |
0.2 | 0.6 | GO:0007189 | adenylate cyclase-activating G-protein coupled receptor signaling pathway(GO:0007189) |
0.2 | 1.3 | GO:0009231 | riboflavin metabolic process(GO:0006771) riboflavin biosynthetic process(GO:0009231) |
0.2 | 0.6 | GO:0031555 | transcriptional attenuation(GO:0031555) transcription antitermination(GO:0031564) |
0.2 | 1.6 | GO:0034965 | intronic snoRNA processing(GO:0031070) intronic box C/D snoRNA processing(GO:0034965) |
0.2 | 2.7 | GO:0031498 | nucleosome disassembly(GO:0006337) chromatin disassembly(GO:0031498) protein-DNA complex disassembly(GO:0032986) |
0.2 | 0.5 | GO:0044818 | mitotic G2/M transition checkpoint(GO:0044818) |
0.2 | 0.5 | GO:0001109 | promoter clearance during DNA-templated transcription(GO:0001109) promoter clearance from RNA polymerase II promoter(GO:0001111) |
0.2 | 2.3 | GO:0007120 | axial cellular bud site selection(GO:0007120) |
0.2 | 0.9 | GO:0046459 | short-chain fatty acid metabolic process(GO:0046459) |
0.2 | 0.5 | GO:0043069 | negative regulation of apoptotic process(GO:0043066) negative regulation of programmed cell death(GO:0043069) negative regulation of cell death(GO:0060548) |
0.2 | 1.5 | GO:0071039 | U5 snRNA 3'-end processing(GO:0034476) nuclear polyadenylation-dependent CUT catabolic process(GO:0071039) |
0.2 | 0.8 | GO:0046391 | 5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391) |
0.2 | 1.0 | GO:0045292 | mRNA cis splicing, via spliceosome(GO:0045292) |
0.2 | 2.3 | GO:0042790 | transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:0042790) |
0.2 | 2.9 | GO:0000011 | vacuole inheritance(GO:0000011) |
0.2 | 0.2 | GO:0071482 | cellular response to radiation(GO:0071478) cellular response to light stimulus(GO:0071482) |
0.2 | 1.1 | GO:0043666 | regulation of phosphoprotein phosphatase activity(GO:0043666) |
0.2 | 0.6 | GO:0071406 | response to methylmercury(GO:0051597) cellular response to methylmercury(GO:0071406) |
0.2 | 0.3 | GO:0051865 | protein autoubiquitination(GO:0051865) |
0.2 | 0.3 | GO:0070072 | proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072) |
0.2 | 0.3 | GO:0031684 | heterotrimeric G-protein complex cycle(GO:0031684) |
0.2 | 0.5 | GO:0033241 | regulation of cellular amine catabolic process(GO:0033241) |
0.1 | 0.7 | GO:0060277 | obsolete negative regulation of transcription involved in G1 phase of mitotic cell cycle(GO:0060277) |
0.1 | 0.7 | GO:0006814 | sodium ion transport(GO:0006814) |
0.1 | 0.3 | GO:0070827 | chromatin maintenance(GO:0070827) |
0.1 | 3.3 | GO:0006885 | regulation of pH(GO:0006885) |
0.1 | 0.6 | GO:0006797 | polyphosphate metabolic process(GO:0006797) |
0.1 | 0.9 | GO:0006617 | SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition(GO:0006617) |
0.1 | 3.4 | GO:0030148 | sphingolipid biosynthetic process(GO:0030148) |
0.1 | 0.4 | GO:0006529 | asparagine biosynthetic process(GO:0006529) |
0.1 | 1.1 | GO:0000376 | Group I intron splicing(GO:0000372) RNA splicing, via transesterification reactions with guanosine as nucleophile(GO:0000376) |
0.1 | 0.7 | GO:0007030 | Golgi organization(GO:0007030) |
0.1 | 2.4 | GO:0030488 | tRNA methylation(GO:0030488) |
0.1 | 1.5 | GO:0045943 | positive regulation of transcription from RNA polymerase I promoter(GO:0045943) |
0.1 | 1.1 | GO:0006384 | transcription initiation from RNA polymerase III promoter(GO:0006384) |
0.1 | 0.4 | GO:0038032 | termination of signal transduction(GO:0023021) termination of G-protein coupled receptor signaling pathway(GO:0038032) |
0.1 | 0.6 | GO:0007009 | plasma membrane organization(GO:0007009) |
0.1 | 1.7 | GO:0031110 | regulation of microtubule polymerization or depolymerization(GO:0031110) |
0.1 | 0.2 | GO:0033865 | coenzyme A metabolic process(GO:0015936) nucleoside bisphosphate metabolic process(GO:0033865) ribonucleoside bisphosphate metabolic process(GO:0033875) purine nucleoside bisphosphate metabolic process(GO:0034032) |
0.1 | 1.0 | GO:0009395 | phospholipid catabolic process(GO:0009395) |
0.1 | 3.8 | GO:0098876 | Golgi to plasma membrane transport(GO:0006893) vesicle-mediated transport to the plasma membrane(GO:0098876) |
0.1 | 0.8 | GO:0006901 | vesicle coating(GO:0006901) |
0.1 | 0.6 | GO:0043619 | regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0043619) |
0.1 | 0.5 | GO:0006344 | maintenance of chromatin silencing(GO:0006344) maintenance of chromatin silencing at telomere(GO:0035392) protein targeting to nuclear inner membrane(GO:0036228) |
0.1 | 0.4 | GO:0006857 | oligopeptide transport(GO:0006857) |
0.1 | 1.5 | GO:0006369 | termination of RNA polymerase II transcription(GO:0006369) |
0.1 | 2.4 | GO:0009267 | cellular response to starvation(GO:0009267) |
0.1 | 0.3 | GO:0046677 | response to antibiotic(GO:0046677) |
0.1 | 3.8 | GO:1902593 | protein import into nucleus(GO:0006606) protein targeting to nucleus(GO:0044744) nuclear import(GO:0051170) single-organism nuclear import(GO:1902593) |
0.1 | 0.3 | GO:0043171 | peptide catabolic process(GO:0043171) |
0.1 | 0.8 | GO:0006616 | SRP-dependent cotranslational protein targeting to membrane, translocation(GO:0006616) |
0.1 | 0.9 | GO:0006882 | cellular zinc ion homeostasis(GO:0006882) zinc ion homeostasis(GO:0055069) |
0.1 | 0.8 | GO:0016559 | peroxisome fission(GO:0016559) |
0.1 | 2.0 | GO:0006469 | negative regulation of protein kinase activity(GO:0006469) |
0.1 | 2.1 | GO:0000027 | ribosomal large subunit assembly(GO:0000027) |
0.1 | 1.0 | GO:0007021 | tubulin complex assembly(GO:0007021) |
0.1 | 0.4 | GO:0034316 | negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316) negative regulation of actin nucleation(GO:0051126) |
0.1 | 0.8 | GO:0070525 | tRNA threonylcarbamoyladenosine metabolic process(GO:0070525) |
0.1 | 1.4 | GO:0006379 | mRNA cleavage(GO:0006379) |
0.1 | 0.2 | GO:0045048 | protein insertion into ER membrane(GO:0045048) |
0.1 | 1.1 | GO:0006098 | pentose-phosphate shunt(GO:0006098) glyceraldehyde-3-phosphate metabolic process(GO:0019682) |
0.1 | 0.2 | GO:0033559 | unsaturated fatty acid biosynthetic process(GO:0006636) unsaturated fatty acid metabolic process(GO:0033559) |
0.1 | 1.4 | GO:0006283 | transcription-coupled nucleotide-excision repair(GO:0006283) |
0.1 | 0.1 | GO:0000304 | response to singlet oxygen(GO:0000304) |
0.1 | 0.7 | GO:0006450 | regulation of translational fidelity(GO:0006450) |
0.1 | 0.3 | GO:0018196 | peptidyl-asparagine modification(GO:0018196) protein N-linked glycosylation via asparagine(GO:0018279) |
0.1 | 2.2 | GO:0042147 | retrograde transport, endosome to Golgi(GO:0042147) |
0.1 | 0.2 | GO:1901977 | regulation of cell cycle checkpoint(GO:1901976) negative regulation of cell cycle checkpoint(GO:1901977) regulation of DNA damage checkpoint(GO:2000001) negative regulation of DNA damage checkpoint(GO:2000002) negative regulation of response to DNA damage stimulus(GO:2001021) |
0.1 | 0.6 | GO:0006037 | cell wall chitin metabolic process(GO:0006037) |
0.1 | 0.5 | GO:0001402 | signal transduction involved in filamentous growth(GO:0001402) |
0.1 | 0.3 | GO:0006657 | CDP-choline pathway(GO:0006657) |
0.1 | 1.5 | GO:0071428 | ribosomal subunit export from nucleus(GO:0000054) ribosome localization(GO:0033750) establishment of ribosome localization(GO:0033753) rRNA-containing ribonucleoprotein complex export from nucleus(GO:0071428) |
0.1 | 0.5 | GO:0030011 | maintenance of cell polarity(GO:0030011) |
0.1 | 0.4 | GO:0042823 | pyridoxal phosphate metabolic process(GO:0042822) pyridoxal phosphate biosynthetic process(GO:0042823) aldehyde biosynthetic process(GO:0046184) |
0.1 | 1.2 | GO:0045047 | protein targeting to ER(GO:0045047) |
0.1 | 0.1 | GO:0043902 | positive regulation of multi-organism process(GO:0043902) |
0.1 | 1.8 | GO:0006418 | tRNA aminoacylation for protein translation(GO:0006418) |
0.1 | 0.3 | GO:0035376 | sterol import(GO:0035376) |
0.1 | 0.1 | GO:0006363 | termination of RNA polymerase I transcription(GO:0006363) |
0.1 | 0.3 | GO:0031087 | deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087) |
0.1 | 0.2 | GO:0051318 | mitotic G1 phase(GO:0000080) G1 phase(GO:0051318) |
0.1 | 0.2 | GO:0015691 | cadmium ion transport(GO:0015691) |
0.1 | 0.5 | GO:0016233 | telomere capping(GO:0016233) |
0.1 | 0.1 | GO:0032368 | regulation of lipid transport(GO:0032368) |
0.1 | 0.2 | GO:0007535 | donor selection(GO:0007535) |
0.1 | 0.3 | GO:1901879 | regulation of actin filament depolymerization(GO:0030834) negative regulation of actin filament depolymerization(GO:0030835) barbed-end actin filament capping(GO:0051016) actin filament capping(GO:0051693) regulation of protein depolymerization(GO:1901879) negative regulation of protein depolymerization(GO:1901880) |
0.1 | 0.2 | GO:0035999 | tetrahydrofolate interconversion(GO:0035999) |
0.1 | 1.4 | GO:0000480 | endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000480) |
0.1 | 0.8 | GO:0031929 | TOR signaling(GO:0031929) |
0.1 | 1.1 | GO:0032508 | DNA duplex unwinding(GO:0032508) |
0.1 | 0.1 | GO:0009202 | deoxyribonucleoside triphosphate biosynthetic process(GO:0009202) |
0.1 | 0.2 | GO:0006264 | mitochondrial DNA replication(GO:0006264) |
0.1 | 0.5 | GO:0006189 | 'de novo' IMP biosynthetic process(GO:0006189) |
0.1 | 0.5 | GO:0016973 | poly(A)+ mRNA export from nucleus(GO:0016973) |
0.1 | 0.9 | GO:0006414 | translational elongation(GO:0006414) |
0.1 | 0.1 | GO:0015809 | arginine transport(GO:0015809) |
0.1 | 1.8 | GO:0042273 | ribosomal large subunit biogenesis(GO:0042273) |
0.1 | 0.2 | GO:0016578 | histone deubiquitination(GO:0016578) |
0.1 | 0.2 | GO:0019357 | nicotinate nucleotide biosynthetic process(GO:0019357) nicotinate nucleotide salvage(GO:0019358) pyridine nucleotide salvage(GO:0019365) nicotinate nucleotide metabolic process(GO:0046497) |
0.1 | 0.2 | GO:0006378 | mRNA polyadenylation(GO:0006378) |
0.1 | 0.5 | GO:0008298 | intracellular mRNA localization(GO:0008298) |
0.0 | 0.8 | GO:0006446 | regulation of translational initiation(GO:0006446) |
0.0 | 1.5 | GO:0006487 | protein N-linked glycosylation(GO:0006487) |
0.0 | 0.4 | GO:0006730 | one-carbon metabolic process(GO:0006730) |
0.0 | 0.2 | GO:0000730 | meiotic DNA recombinase assembly(GO:0000707) DNA recombinase assembly(GO:0000730) |
0.0 | 0.1 | GO:0061572 | actin filament bundle assembly(GO:0051017) actin filament bundle organization(GO:0061572) |
0.0 | 0.0 | GO:0031590 | wybutosine metabolic process(GO:0031590) wybutosine biosynthetic process(GO:0031591) |
0.0 | 3.1 | GO:0006364 | rRNA processing(GO:0006364) |
0.0 | 0.1 | GO:0016074 | snoRNA metabolic process(GO:0016074) |
0.0 | 0.1 | GO:0002943 | tRNA dihydrouridine synthesis(GO:0002943) |
0.0 | 1.1 | GO:0051169 | nucleocytoplasmic transport(GO:0006913) nuclear transport(GO:0051169) |
0.0 | 0.1 | GO:0043489 | RNA stabilization(GO:0043489) mRNA stabilization(GO:0048255) |
0.0 | 0.1 | GO:0006003 | fructose 2,6-bisphosphate metabolic process(GO:0006003) |
0.0 | 0.2 | GO:0034314 | Arp2/3 complex-mediated actin nucleation(GO:0034314) |
0.0 | 0.2 | GO:0046020 | negative regulation of transcription by pheromones(GO:0045996) negative regulation of transcription from RNA polymerase II promoter by pheromones(GO:0046020) |
0.0 | 0.4 | GO:0070816 | phosphorylation of RNA polymerase II C-terminal domain(GO:0070816) |
0.0 | 0.2 | GO:0048280 | vesicle fusion with Golgi apparatus(GO:0048280) |
0.0 | 0.1 | GO:0042594 | response to starvation(GO:0042594) |
0.0 | 0.1 | GO:0042274 | ribosomal small subunit biogenesis(GO:0042274) |
0.0 | 0.1 | GO:0031930 | mitochondria-nucleus signaling pathway(GO:0031930) |
0.0 | 0.4 | GO:0000413 | protein peptidyl-prolyl isomerization(GO:0000413) peptidyl-proline modification(GO:0018208) |
0.0 | 0.1 | GO:0007119 | budding cell isotropic bud growth(GO:0007119) |
0.0 | 0.3 | GO:0044396 | actin cortical patch assembly(GO:0000147) actin cortical patch organization(GO:0044396) |
0.0 | 0.4 | GO:0006144 | purine nucleobase metabolic process(GO:0006144) |
0.0 | 0.3 | GO:0016925 | protein sumoylation(GO:0016925) |
0.0 | 0.1 | GO:0071454 | response to anoxia(GO:0034059) cellular response to anoxia(GO:0071454) |
0.0 | 0.7 | GO:0006506 | GPI anchor biosynthetic process(GO:0006506) |
0.0 | 0.2 | GO:0006526 | arginine biosynthetic process(GO:0006526) |
0.0 | 0.3 | GO:0030474 | spindle pole body duplication(GO:0030474) |
0.0 | 0.1 | GO:0006596 | polyamine biosynthetic process(GO:0006596) |
0.0 | 0.1 | GO:0010674 | negative regulation of transcription from RNA polymerase II promoter involved in meiotic cell cycle(GO:0010674) |
0.0 | 0.2 | GO:0006878 | cellular copper ion homeostasis(GO:0006878) copper ion homeostasis(GO:0055070) |
0.0 | 0.6 | GO:0006413 | translational initiation(GO:0006413) |
0.0 | 0.3 | GO:0030473 | establishment of localization by movement along microtubule(GO:0010970) nuclear migration along microtubule(GO:0030473) organelle transport along microtubule(GO:0072384) |
0.0 | 0.1 | GO:0008299 | isoprenoid metabolic process(GO:0006720) isoprenoid biosynthetic process(GO:0008299) |
0.0 | 1.0 | GO:0030036 | actin cytoskeleton organization(GO:0030036) |
0.0 | 0.1 | GO:0090630 | activation of GTPase activity(GO:0090630) |
0.0 | 0.1 | GO:0048279 | vesicle fusion with endoplasmic reticulum(GO:0048279) |
0.0 | 0.3 | GO:0006890 | retrograde vesicle-mediated transport, Golgi to ER(GO:0006890) |
0.0 | 0.1 | GO:0015680 | intracellular copper ion transport(GO:0015680) |
0.0 | 0.0 | GO:0070507 | regulation of microtubule-based process(GO:0032886) regulation of microtubule cytoskeleton organization(GO:0070507) |
0.0 | 0.3 | GO:0009304 | tRNA transcription(GO:0009304) tRNA transcription from RNA polymerase III promoter(GO:0042797) |
0.0 | 0.1 | GO:0006388 | tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388) |
0.0 | 0.1 | GO:0070682 | proteasome regulatory particle assembly(GO:0070682) |
0.0 | 0.0 | GO:0006517 | protein deglycosylation(GO:0006517) |
0.0 | 0.1 | GO:0035335 | peptidyl-tyrosine dephosphorylation(GO:0035335) |
0.0 | 0.0 | GO:0070676 | intralumenal vesicle formation(GO:0070676) |
0.0 | 0.4 | GO:0016049 | cell growth(GO:0016049) |
0.0 | 0.1 | GO:0000076 | DNA replication checkpoint(GO:0000076) |
0.0 | 0.1 | GO:0006493 | protein O-linked glycosylation(GO:0006493) |
0.0 | 0.0 | GO:0016926 | protein desumoylation(GO:0016926) |
0.0 | 0.1 | GO:0034501 | protein localization to kinetochore(GO:0034501) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.8 | 5.5 | GO:0032299 | ribonuclease H2 complex(GO:0032299) |
0.5 | 33.0 | GO:0022627 | cytosolic small ribosomal subunit(GO:0022627) |
0.5 | 1.5 | GO:0009331 | glycerol-3-phosphate dehydrogenase complex(GO:0009331) |
0.5 | 1.4 | GO:0031415 | NatA complex(GO:0031415) |
0.4 | 1.3 | GO:0070545 | PeBoW complex(GO:0070545) |
0.4 | 1.3 | GO:0017102 | methionyl glutamyl tRNA synthetase complex(GO:0017102) |
0.4 | 1.2 | GO:0043625 | delta DNA polymerase complex(GO:0043625) |
0.4 | 1.5 | GO:0032160 | septin filament array(GO:0032160) |
0.4 | 29.6 | GO:0022625 | cytosolic large ribosomal subunit(GO:0022625) |
0.3 | 1.3 | GO:0070860 | RNA polymerase I core factor complex(GO:0070860) |
0.3 | 1.7 | GO:0043527 | tRNA methyltransferase complex(GO:0043527) |
0.3 | 3.6 | GO:0000786 | nucleosome(GO:0000786) |
0.3 | 0.8 | GO:0030428 | cell septum(GO:0030428) |
0.3 | 1.5 | GO:0005871 | kinesin complex(GO:0005871) |
0.2 | 4.1 | GO:0000307 | cyclin-dependent protein kinase holoenzyme complex(GO:0000307) |
0.2 | 1.7 | GO:0000346 | transcription export complex(GO:0000346) |
0.2 | 2.8 | GO:0016514 | SWI/SNF complex(GO:0016514) BAF-type complex(GO:0090544) |
0.2 | 1.6 | GO:0019773 | proteasome core complex, alpha-subunit complex(GO:0019773) |
0.2 | 0.9 | GO:0005946 | alpha,alpha-trehalose-phosphate synthase complex (UDP-forming)(GO:0005946) |
0.2 | 1.8 | GO:0033101 | cellular bud membrane(GO:0033101) |
0.2 | 0.9 | GO:0005971 | ribonucleoside-diphosphate reductase complex(GO:0005971) |
0.2 | 0.6 | GO:0070985 | TFIIK complex(GO:0070985) |
0.2 | 1.4 | GO:0034455 | t-UTP complex(GO:0034455) |
0.2 | 1.3 | GO:0019774 | proteasome core complex, beta-subunit complex(GO:0019774) |
0.2 | 1.0 | GO:0005853 | eukaryotic translation elongation factor 1 complex(GO:0005853) |
0.2 | 0.6 | GO:0042719 | mitochondrial intermembrane space protein transporter complex(GO:0042719) |
0.2 | 1.3 | GO:0072686 | mitotic spindle(GO:0072686) |
0.2 | 1.6 | GO:0005655 | nucleolar ribonuclease P complex(GO:0005655) multimeric ribonuclease P complex(GO:0030681) |
0.2 | 1.9 | GO:0005832 | chaperonin-containing T-complex(GO:0005832) |
0.2 | 0.9 | GO:0005641 | nuclear envelope lumen(GO:0005641) |
0.2 | 0.8 | GO:0030689 | Noc complex(GO:0030689) |
0.2 | 0.8 | GO:0000408 | EKC/KEOPS complex(GO:0000408) |
0.2 | 1.8 | GO:0005940 | septin ring(GO:0005940) |
0.2 | 2.1 | GO:0005736 | DNA-directed RNA polymerase I complex(GO:0005736) |
0.1 | 0.6 | GO:0033254 | vacuolar transporter chaperone complex(GO:0033254) |
0.1 | 0.9 | GO:0048500 | signal recognition particle, endoplasmic reticulum targeting(GO:0005786) signal recognition particle(GO:0048500) |
0.1 | 0.7 | GO:0034518 | RNA cap binding complex(GO:0034518) |
0.1 | 0.4 | GO:0071261 | Ssh1 translocon complex(GO:0071261) |
0.1 | 4.9 | GO:0030687 | preribosome, large subunit precursor(GO:0030687) |
0.1 | 0.9 | GO:0005665 | DNA-directed RNA polymerase II, core complex(GO:0005665) |
0.1 | 0.6 | GO:0008622 | epsilon DNA polymerase complex(GO:0008622) |
0.1 | 0.8 | GO:0016272 | prefoldin complex(GO:0016272) |
0.1 | 0.4 | GO:0044697 | HICS complex(GO:0044697) |
0.1 | 1.7 | GO:0022626 | cytosolic ribosome(GO:0022626) |
0.1 | 1.6 | GO:0016586 | RSC complex(GO:0016586) |
0.1 | 0.6 | GO:0005851 | eukaryotic translation initiation factor 2B complex(GO:0005851) |
0.1 | 1.2 | GO:0005666 | DNA-directed RNA polymerase III complex(GO:0005666) |
0.1 | 1.6 | GO:0000176 | nuclear exosome (RNase complex)(GO:0000176) |
0.1 | 0.8 | GO:0000221 | vacuolar proton-transporting V-type ATPase, V1 domain(GO:0000221) proton-transporting V-type ATPase, V1 domain(GO:0033180) |
0.1 | 0.7 | GO:0017059 | serine C-palmitoyltransferase complex(GO:0017059) SPOTS complex(GO:0035339) |
0.1 | 0.9 | GO:0030126 | COPI vesicle coat(GO:0030126) |
0.1 | 4.2 | GO:0005811 | lipid particle(GO:0005811) |
0.1 | 2.1 | GO:0005849 | mRNA cleavage factor complex(GO:0005849) |
0.1 | 0.8 | GO:0044615 | nuclear pore nuclear basket(GO:0044615) |
0.1 | 1.2 | GO:0034399 | nuclear periphery(GO:0034399) |
0.1 | 0.3 | GO:0005827 | polar microtubule(GO:0005827) tubulin complex(GO:0045298) |
0.1 | 0.4 | GO:0030907 | MBF transcription complex(GO:0030907) |
0.1 | 18.0 | GO:0005933 | cellular bud(GO:0005933) |
0.1 | 0.4 | GO:0017053 | transcriptional repressor complex(GO:0017053) |
0.1 | 0.7 | GO:0051233 | spindle midzone(GO:0051233) |
0.1 | 0.3 | GO:0070939 | Dsl1p complex(GO:0070939) |
0.1 | 0.4 | GO:0000938 | GARP complex(GO:0000938) |
0.1 | 2.2 | GO:0005802 | trans-Golgi network(GO:0005802) |
0.1 | 0.4 | GO:0000131 | incipient cellular bud site(GO:0000131) |
0.1 | 0.3 | GO:0044611 | nuclear pore inner ring(GO:0044611) |
0.1 | 0.6 | GO:0005697 | telomerase holoenzyme complex(GO:0005697) |
0.1 | 0.5 | GO:0005852 | eukaryotic translation initiation factor 3 complex(GO:0005852) |
0.1 | 0.2 | GO:0042575 | DNA polymerase complex(GO:0042575) |
0.1 | 0.3 | GO:0005834 | heterotrimeric G-protein complex(GO:0005834) |
0.1 | 0.5 | GO:0000783 | telomere cap complex(GO:0000782) nuclear telomere cap complex(GO:0000783) |
0.1 | 0.4 | GO:0031414 | N-terminal protein acetyltransferase complex(GO:0031414) |
0.1 | 0.2 | GO:0042729 | DASH complex(GO:0042729) |
0.1 | 0.4 | GO:0000136 | alpha-1,6-mannosyltransferase complex(GO:0000136) |
0.1 | 0.3 | GO:0030906 | retromer, cargo-selective complex(GO:0030906) |
0.1 | 0.3 | GO:0005823 | central plaque of spindle pole body(GO:0005823) |
0.1 | 0.3 | GO:0034990 | mitotic cohesin complex(GO:0030892) nuclear mitotic cohesin complex(GO:0034990) |
0.1 | 0.4 | GO:0030121 | AP-1 adaptor complex(GO:0030121) |
0.1 | 1.2 | GO:0005685 | U1 snRNP(GO:0005685) |
0.1 | 0.2 | GO:0033186 | CAF-1 complex(GO:0033186) |
0.1 | 0.2 | GO:0043529 | GET complex(GO:0043529) |
0.1 | 0.6 | GO:0000792 | heterochromatin(GO:0000792) |
0.1 | 8.8 | GO:0005730 | nucleolus(GO:0005730) |
0.1 | 0.2 | GO:0016587 | Isw1 complex(GO:0016587) |
0.1 | 0.6 | GO:0008540 | proteasome regulatory particle, base subcomplex(GO:0008540) |
0.1 | 0.1 | GO:0070762 | nuclear pore transmembrane ring(GO:0070762) |
0.0 | 0.2 | GO:0034044 | exomer complex(GO:0034044) |
0.0 | 0.6 | GO:0030014 | CCR4-NOT complex(GO:0030014) |
0.0 | 0.2 | GO:0033179 | vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220) proton-transporting V-type ATPase, V0 domain(GO:0033179) |
0.0 | 0.3 | GO:0042555 | MCM complex(GO:0042555) |
0.0 | 1.6 | GO:0030134 | ER to Golgi transport vesicle(GO:0030134) |
0.0 | 0.1 | GO:0005850 | eukaryotic translation initiation factor 2 complex(GO:0005850) |
0.0 | 0.3 | GO:0008250 | oligosaccharyltransferase complex(GO:0008250) |
0.0 | 0.2 | GO:0071819 | DUBm complex(GO:0071819) |
0.0 | 0.4 | GO:0005637 | nuclear inner membrane(GO:0005637) |
0.0 | 0.5 | GO:0098857 | membrane raft(GO:0045121) membrane microdomain(GO:0098857) |
0.0 | 0.0 | GO:0000133 | polarisome(GO:0000133) |
0.0 | 0.5 | GO:0046695 | SLIK (SAGA-like) complex(GO:0046695) |
0.0 | 0.1 | GO:0005825 | half bridge of spindle pole body(GO:0005825) |
0.0 | 0.2 | GO:0016281 | eukaryotic translation initiation factor 4F complex(GO:0016281) |
0.0 | 0.2 | GO:0044614 | nuclear pore cytoplasmic filaments(GO:0044614) |
0.0 | 0.1 | GO:0035649 | Nrd1 complex(GO:0035649) |
0.0 | 3.5 | GO:0005840 | ribosome(GO:0005840) |
0.0 | 0.1 | GO:0097042 | extrinsic component of fungal-type vacuolar membrane(GO:0097042) |
0.0 | 0.5 | GO:0031902 | late endosome membrane(GO:0031902) |
0.0 | 0.2 | GO:0045277 | mitochondrial respiratory chain complex IV(GO:0005751) respiratory chain complex IV(GO:0045277) |
0.0 | 0.1 | GO:0005797 | Golgi medial cisterna(GO:0005797) |
0.0 | 0.3 | GO:0005881 | cytoplasmic microtubule(GO:0005881) |
0.0 | 1.0 | GO:0030479 | actin cortical patch(GO:0030479) endocytic patch(GO:0061645) |
0.0 | 0.1 | GO:0005968 | Rab-protein geranylgeranyltransferase complex(GO:0005968) |
0.0 | 0.3 | GO:0019005 | SCF ubiquitin ligase complex(GO:0019005) |
0.0 | 0.1 | GO:0000815 | ESCRT III complex(GO:0000815) |
0.0 | 0.3 | GO:0005788 | endoplasmic reticulum lumen(GO:0005788) |
0.0 | 0.9 | GO:0031225 | anchored component of membrane(GO:0031225) |
0.0 | 0.3 | GO:0005779 | integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231) |
0.0 | 0.1 | GO:0000137 | Golgi cis cisterna(GO:0000137) |
0.0 | 0.1 | GO:0005682 | U5 snRNP(GO:0005682) |
0.0 | 0.3 | GO:0005844 | polysome(GO:0005844) |
0.0 | 0.1 | GO:0005742 | mitochondrial outer membrane translocase complex(GO:0005742) |
0.0 | 0.1 | GO:0000506 | glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506) |
0.0 | 0.1 | GO:0000818 | MIS12/MIND type complex(GO:0000444) nuclear MIS12/MIND complex(GO:0000818) |
0.0 | 0.1 | GO:0017119 | Golgi transport complex(GO:0017119) |
0.0 | 0.5 | GO:0030176 | integral component of endoplasmic reticulum membrane(GO:0030176) |
0.0 | 0.1 | GO:0046540 | U4/U6 x U5 tri-snRNP complex(GO:0046540) spliceosomal tri-snRNP complex(GO:0097526) |
0.0 | 0.1 | GO:0044613 | nuclear pore central transport channel(GO:0044613) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.9 | 5.7 | GO:0042910 | xenobiotic-transporting ATPase activity(GO:0008559) xenobiotic transporter activity(GO:0042910) |
1.4 | 5.5 | GO:0004523 | RNA-DNA hybrid ribonuclease activity(GO:0004523) |
1.3 | 5.0 | GO:0016634 | oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor(GO:0016634) |
0.9 | 2.7 | GO:0010521 | telomerase inhibitor activity(GO:0010521) |
0.9 | 5.3 | GO:0016846 | carbon-sulfur lyase activity(GO:0016846) |
0.8 | 2.5 | GO:0016872 | intramolecular lyase activity(GO:0016872) |
0.8 | 3.4 | GO:0016841 | ammonia-lyase activity(GO:0016841) |
0.8 | 3.2 | GO:0000297 | spermine transmembrane transporter activity(GO:0000297) |
0.8 | 2.3 | GO:0051219 | phosphoprotein binding(GO:0051219) |
0.7 | 2.0 | GO:0015114 | phosphate ion transmembrane transporter activity(GO:0015114) |
0.7 | 2.0 | GO:0016717 | oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water(GO:0016717) |
0.6 | 3.2 | GO:0008536 | Ran GTPase binding(GO:0008536) |
0.6 | 3.1 | GO:0008525 | phosphatidylcholine transporter activity(GO:0008525) phosphatidylinositol transporter activity(GO:0008526) |
0.6 | 1.7 | GO:0004809 | tRNA (guanine-N2-)-methyltransferase activity(GO:0004809) |
0.5 | 2.7 | GO:0050072 | m7G(5')pppN diphosphatase activity(GO:0050072) |
0.5 | 2.1 | GO:0004467 | long-chain fatty acid-CoA ligase activity(GO:0004467) |
0.5 | 3.1 | GO:0003906 | DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906) |
0.5 | 5.1 | GO:0001133 | RNA polymerase II transcription factor activity, sequence-specific transcription regulatory region DNA binding(GO:0001133) |
0.5 | 2.0 | GO:0004622 | lysophospholipase activity(GO:0004622) |
0.5 | 1.8 | GO:0008079 | translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079) |
0.4 | 1.3 | GO:0003938 | IMP dehydrogenase activity(GO:0003938) |
0.4 | 1.7 | GO:0004338 | glucan exo-1,3-beta-glucosidase activity(GO:0004338) |
0.3 | 2.1 | GO:0016744 | transferase activity, transferring aldehyde or ketonic groups(GO:0016744) |
0.3 | 3.0 | GO:0004497 | monooxygenase activity(GO:0004497) |
0.3 | 1.0 | GO:0004525 | ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296) |
0.3 | 0.6 | GO:0008097 | 5S rRNA binding(GO:0008097) |
0.3 | 2.9 | GO:0005545 | 1-phosphatidylinositol binding(GO:0005545) |
0.3 | 1.3 | GO:0008157 | protein phosphatase 1 binding(GO:0008157) |
0.3 | 1.3 | GO:0001186 | core promoter sequence-specific DNA binding(GO:0001046) transcription factor activity, RNA polymerase I transcription factor recruiting(GO:0001186) |
0.3 | 3.8 | GO:0005199 | structural constituent of cell wall(GO:0005199) |
0.3 | 0.9 | GO:0004805 | trehalose-phosphatase activity(GO:0004805) |
0.3 | 1.2 | GO:0008310 | 3'-5'-exodeoxyribonuclease activity(GO:0008296) single-stranded DNA exodeoxyribonuclease activity(GO:0008297) single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310) |
0.3 | 60.2 | GO:0003735 | structural constituent of ribosome(GO:0003735) |
0.3 | 0.9 | GO:0003841 | 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841) |
0.3 | 6.2 | GO:0019901 | protein kinase binding(GO:0019901) |
0.3 | 3.1 | GO:0043495 | protein anchor(GO:0043495) |
0.3 | 0.8 | GO:0008271 | secondary active sulfate transmembrane transporter activity(GO:0008271) sulfate transmembrane transporter activity(GO:0015116) |
0.3 | 0.8 | GO:0072341 | modified amino acid binding(GO:0072341) |
0.3 | 1.1 | GO:0051377 | mannose-ethanolamine phosphotransferase activity(GO:0051377) |
0.3 | 1.4 | GO:0070546 | L-phenylalanine aminotransferase activity(GO:0070546) L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130) |
0.3 | 1.1 | GO:0015230 | FAD transmembrane transporter activity(GO:0015230) |
0.3 | 0.8 | GO:0043023 | ribosomal large subunit binding(GO:0043023) |
0.3 | 3.5 | GO:0001078 | transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078) |
0.2 | 0.7 | GO:0015166 | polyol transmembrane transporter activity(GO:0015166) |
0.2 | 0.7 | GO:0070568 | guanylyltransferase activity(GO:0070568) |
0.2 | 0.9 | GO:0001055 | RNA polymerase II activity(GO:0001055) |
0.2 | 1.4 | GO:0015198 | oligopeptide transporter activity(GO:0015198) |
0.2 | 0.7 | GO:0000339 | RNA cap binding(GO:0000339) |
0.2 | 0.7 | GO:0004488 | methylenetetrahydrofolate dehydrogenase (NADP+) activity(GO:0004488) |
0.2 | 1.1 | GO:0042124 | glucanosyltransferase activity(GO:0042123) 1,3-beta-glucanosyltransferase activity(GO:0042124) |
0.2 | 0.9 | GO:0016728 | ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups(GO:0016725) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731) |
0.2 | 3.0 | GO:0070003 | threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003) |
0.2 | 7.7 | GO:0016765 | transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765) |
0.2 | 1.8 | GO:0004596 | peptide alpha-N-acetyltransferase activity(GO:0004596) |
0.2 | 0.6 | GO:0004826 | phenylalanine-tRNA ligase activity(GO:0004826) |
0.2 | 0.5 | GO:0051010 | microtubule plus-end binding(GO:0051010) |
0.2 | 0.9 | GO:0008312 | 7S RNA binding(GO:0008312) |
0.2 | 0.7 | GO:0016886 | ligase activity, forming phosphoric ester bonds(GO:0016886) |
0.2 | 0.8 | GO:0070403 | NAD+ binding(GO:0070403) |
0.2 | 0.8 | GO:0004749 | ribose phosphate diphosphokinase activity(GO:0004749) |
0.2 | 0.7 | GO:0050291 | sphingosine N-acyltransferase activity(GO:0050291) |
0.2 | 2.8 | GO:0016763 | transferase activity, transferring pentosyl groups(GO:0016763) |
0.2 | 1.6 | GO:0000171 | ribonuclease MRP activity(GO:0000171) |
0.2 | 0.8 | GO:0016538 | cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538) |
0.2 | 1.7 | GO:0004860 | protein kinase inhibitor activity(GO:0004860) |
0.2 | 0.9 | GO:0016408 | C-acyltransferase activity(GO:0016408) |
0.2 | 2.1 | GO:0001054 | RNA polymerase I activity(GO:0001054) |
0.2 | 1.5 | GO:0003777 | microtubule motor activity(GO:0003777) |
0.2 | 0.6 | GO:0005527 | macrolide binding(GO:0005527) FK506 binding(GO:0005528) |
0.1 | 1.0 | GO:0019201 | nucleotide kinase activity(GO:0019201) |
0.1 | 0.9 | GO:0003725 | double-stranded RNA binding(GO:0003725) |
0.1 | 0.5 | GO:0034450 | ubiquitin-ubiquitin ligase activity(GO:0034450) |
0.1 | 1.1 | GO:0016702 | oxidoreductase activity, acting on single donors with incorporation of molecular oxygen(GO:0016701) oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702) |
0.1 | 0.1 | GO:0019003 | GDP binding(GO:0019003) |
0.1 | 3.6 | GO:0046982 | protein heterodimerization activity(GO:0046982) |
0.1 | 0.4 | GO:0004128 | cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128) |
0.1 | 2.0 | GO:0015616 | DNA translocase activity(GO:0015616) |
0.1 | 1.2 | GO:0001056 | RNA polymerase III activity(GO:0001056) |
0.1 | 1.7 | GO:0003746 | translation elongation factor activity(GO:0003746) |
0.1 | 0.3 | GO:0015248 | sterol transporter activity(GO:0015248) |
0.1 | 1.1 | GO:0005216 | ion channel activity(GO:0005216) |
0.1 | 1.7 | GO:0042162 | telomeric DNA binding(GO:0042162) |
0.1 | 0.5 | GO:0005092 | GDP-dissociation inhibitor activity(GO:0005092) |
0.1 | 0.9 | GO:0031490 | chromatin DNA binding(GO:0031490) |
0.1 | 0.9 | GO:0019904 | protein domain specific binding(GO:0019904) |
0.1 | 0.4 | GO:0000774 | adenyl-nucleotide exchange factor activity(GO:0000774) |
0.1 | 0.5 | GO:0001139 | transcription factor activity, core RNA polymerase II recruiting(GO:0001139) |
0.1 | 0.3 | GO:0003680 | AT DNA binding(GO:0003680) |
0.1 | 0.7 | GO:0030295 | protein kinase activator activity(GO:0030295) |
0.1 | 0.3 | GO:0005034 | osmosensor activity(GO:0005034) |
0.1 | 0.4 | GO:0004679 | AMP-activated protein kinase activity(GO:0004679) |
0.1 | 0.4 | GO:0008443 | phosphofructokinase activity(GO:0008443) |
0.1 | 2.4 | GO:0004722 | protein serine/threonine phosphatase activity(GO:0004722) |
0.1 | 1.5 | GO:0030515 | snoRNA binding(GO:0030515) |
0.1 | 1.0 | GO:0051015 | actin filament binding(GO:0051015) |
0.1 | 0.7 | GO:0015079 | potassium ion transmembrane transporter activity(GO:0015079) |
0.1 | 1.7 | GO:0005484 | SNAP receptor activity(GO:0005484) |
0.1 | 1.0 | GO:0050661 | NADP binding(GO:0050661) |
0.1 | 1.0 | GO:0001671 | ATPase activator activity(GO:0001671) |
0.1 | 0.7 | GO:0030276 | clathrin binding(GO:0030276) |
0.1 | 0.6 | GO:0016861 | intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861) |
0.1 | 0.3 | GO:0000033 | alpha-1,3-mannosyltransferase activity(GO:0000033) |
0.1 | 0.1 | GO:0003840 | gamma-glutamyltransferase activity(GO:0003840) |
0.1 | 0.3 | GO:0009378 | four-way junction helicase activity(GO:0009378) |
0.1 | 1.2 | GO:0004520 | endodeoxyribonuclease activity(GO:0004520) |
0.1 | 2.0 | GO:0008135 | translation factor activity, RNA binding(GO:0008135) |
0.1 | 1.2 | GO:0051287 | NAD binding(GO:0051287) |
0.1 | 0.8 | GO:0008408 | 3'-5' exonuclease activity(GO:0008408) |
0.1 | 3.3 | GO:0003924 | GTPase activity(GO:0003924) |
0.1 | 0.8 | GO:0015035 | protein disulfide oxidoreductase activity(GO:0015035) disulfide oxidoreductase activity(GO:0015036) |
0.1 | 0.2 | GO:0043141 | 5'-3' DNA helicase activity(GO:0043139) ATP-dependent 5'-3' DNA helicase activity(GO:0043141) |
0.1 | 0.5 | GO:0000009 | alpha-1,6-mannosyltransferase activity(GO:0000009) |
0.1 | 1.4 | GO:0004004 | ATP-dependent RNA helicase activity(GO:0004004) |
0.1 | 0.3 | GO:0017048 | Rho GTPase binding(GO:0017048) |
0.1 | 0.2 | GO:0008139 | nuclear localization sequence binding(GO:0008139) |
0.1 | 0.3 | GO:0019237 | centromeric DNA binding(GO:0019237) |
0.1 | 0.1 | GO:0019238 | cyclohydrolase activity(GO:0019238) |
0.1 | 0.3 | GO:0017169 | CDP-alcohol phosphatidyltransferase activity(GO:0017169) |
0.0 | 0.3 | GO:0031386 | protein tag(GO:0031386) |
0.0 | 0.4 | GO:0005516 | calmodulin binding(GO:0005516) |
0.0 | 0.2 | GO:0008106 | aldo-keto reductase (NADP) activity(GO:0004033) alcohol dehydrogenase (NADP+) activity(GO:0008106) |
0.0 | 0.6 | GO:0070566 | adenylyltransferase activity(GO:0070566) |
0.0 | 0.2 | GO:0032934 | steroid binding(GO:0005496) sterol binding(GO:0032934) |
0.0 | 2.2 | GO:0008565 | protein transporter activity(GO:0008565) |
0.0 | 0.3 | GO:0004579 | oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579) |
0.0 | 0.1 | GO:0099516 | ion antiporter activity(GO:0099516) |
0.0 | 0.4 | GO:0042803 | protein homodimerization activity(GO:0042803) |
0.0 | 1.2 | GO:0016875 | aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876) |
0.0 | 0.5 | GO:0019213 | deacetylase activity(GO:0019213) |
0.0 | 0.1 | GO:0017150 | tRNA dihydrouridine synthase activity(GO:0017150) |
0.0 | 0.1 | GO:0036002 | pre-mRNA binding(GO:0036002) |
0.0 | 0.1 | GO:0008252 | nucleotidase activity(GO:0008252) |
0.0 | 0.8 | GO:0017056 | structural constituent of nuclear pore(GO:0017056) |
0.0 | 0.9 | GO:0003779 | actin binding(GO:0003779) |
0.0 | 1.0 | GO:0005200 | structural constituent of cytoskeleton(GO:0005200) |
0.0 | 0.5 | GO:0005525 | GTP binding(GO:0005525) guanyl nucleotide binding(GO:0019001) guanyl ribonucleotide binding(GO:0032561) |
0.0 | 0.1 | GO:0004112 | cyclic-nucleotide phosphodiesterase activity(GO:0004112) |
0.0 | 0.3 | GO:0032947 | protein complex scaffold(GO:0032947) |
0.0 | 0.3 | GO:0070491 | repressing transcription factor binding(GO:0070491) |
0.0 | 0.1 | GO:0008242 | omega peptidase activity(GO:0008242) |
0.0 | 0.1 | GO:0005302 | L-tyrosine transmembrane transporter activity(GO:0005302) L-glutamine transmembrane transporter activity(GO:0015186) L-isoleucine transmembrane transporter activity(GO:0015188) branched-chain amino acid transmembrane transporter activity(GO:0015658) |
0.0 | 0.8 | GO:0016810 | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds(GO:0016810) |
0.0 | 0.2 | GO:0016676 | cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676) |
0.0 | 0.0 | GO:0008902 | hydroxymethylpyrimidine kinase activity(GO:0008902) phosphomethylpyrimidine kinase activity(GO:0008972) |
0.0 | 0.2 | GO:0009982 | pseudouridine synthase activity(GO:0009982) |
0.0 | 0.1 | GO:0016832 | aldehyde-lyase activity(GO:0016832) |
0.0 | 0.2 | GO:0004312 | fatty acid synthase activity(GO:0004312) |
0.0 | 0.2 | GO:0008175 | tRNA methyltransferase activity(GO:0008175) |
0.0 | 0.0 | GO:0008144 | drug binding(GO:0008144) |
0.0 | 0.6 | GO:0030674 | protein binding, bridging(GO:0030674) |
0.0 | 0.2 | GO:0008375 | acetylglucosaminyltransferase activity(GO:0008375) |
0.0 | 0.1 | GO:0004707 | MAP kinase activity(GO:0004707) |
0.0 | 0.1 | GO:0003705 | transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705) |
0.0 | 0.1 | GO:0005086 | ARF guanyl-nucleotide exchange factor activity(GO:0005086) |
0.0 | 1.9 | GO:0004674 | protein serine/threonine kinase activity(GO:0004674) |
0.0 | 0.0 | GO:0005519 | cytoskeletal regulatory protein binding(GO:0005519) |
0.0 | 0.4 | GO:0032266 | phosphatidylinositol-3-phosphate binding(GO:0032266) |
0.0 | 0.1 | GO:0004864 | protein phosphatase inhibitor activity(GO:0004864) phosphatase inhibitor activity(GO:0019212) |
0.0 | 0.5 | GO:0000030 | mannosyltransferase activity(GO:0000030) |
0.0 | 3.3 | GO:0003723 | RNA binding(GO:0003723) |
0.0 | 0.1 | GO:0008601 | protein phosphatase type 2A regulator activity(GO:0008601) |
0.0 | 0.7 | GO:0008289 | lipid binding(GO:0008289) |
0.0 | 0.0 | GO:0005384 | manganese ion transmembrane transporter activity(GO:0005384) |
0.0 | 0.1 | GO:0016833 | oxo-acid-lyase activity(GO:0016833) |
0.0 | 0.2 | GO:0031491 | nucleosome binding(GO:0031491) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.3 | 1.3 | PID UPA UPAR PATHWAY | Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling |
0.2 | 0.6 | PID SHP2 PATHWAY | SHP2 signaling |
0.2 | 0.5 | PID P38 ALPHA BETA DOWNSTREAM PATHWAY | Signaling mediated by p38-alpha and p38-beta |
0.0 | 0.0 | PID TRKR PATHWAY | Neurotrophic factor-mediated Trk receptor signaling |
0.0 | 0.1 | PID HIF1 TFPATHWAY | HIF-1-alpha transcription factor network |
0.0 | 0.1 | SA G1 AND S PHASES | Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition. |
0.0 | 0.1 | PID E2F PATHWAY | E2F transcription factor network |
0.0 | 0.1 | SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES | Genes related to the insulin receptor pathway |
0.0 | 0.2 | PID ATR PATHWAY | ATR signaling pathway |
0.0 | 0.1 | NABA ECM GLYCOPROTEINS | Genes encoding structural ECM glycoproteins |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.0 | 7.9 | REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX | Genes involved in Formation of the ternary complex, and subsequently, the 43S complex |
0.4 | 1.3 | REACTOME SULFUR AMINO ACID METABOLISM | Genes involved in Sulfur amino acid metabolism |
0.4 | 6.4 | REACTOME PEPTIDE CHAIN ELONGATION | Genes involved in Peptide chain elongation |
0.4 | 1.2 | REACTOME CITRIC ACID CYCLE TCA CYCLE | Genes involved in Citric acid cycle (TCA cycle) |
0.4 | 1.5 | REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS | Genes involved in Glycerophospholipid biosynthesis |
0.3 | 2.2 | REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC | Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC |
0.2 | 0.6 | REACTOME SIGNALLING TO ERKS | Genes involved in Signalling to ERKs |
0.2 | 0.4 | REACTOME SIGNALING BY ROBO RECEPTOR | Genes involved in Signaling by Robo receptor |
0.2 | 1.0 | REACTOME SIGNALING BY GPCR | Genes involved in Signaling by GPCR |
0.2 | 0.5 | REACTOME SIGNALING BY RHO GTPASES | Genes involved in Signaling by Rho GTPases |
0.2 | 0.3 | REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS | Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements |
0.1 | 0.7 | REACTOME TRANSLATION | Genes involved in Translation |
0.1 | 0.3 | REACTOME INFLUENZA LIFE CYCLE | Genes involved in Influenza Life Cycle |
0.0 | 0.1 | REACTOME CLEAVAGE OF GROWING TRANSCRIPT IN THE TERMINATION REGION | Genes involved in Cleavage of Growing Transcript in the Termination Region |
0.0 | 0.3 | REACTOME UNWINDING OF DNA | Genes involved in Unwinding of DNA |
0.0 | 0.1 | REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE | Genes involved in Synthesis of PIPs at the Golgi membrane |
0.0 | 0.0 | REACTOME CYTOKINE SIGNALING IN IMMUNE SYSTEM | Genes involved in Cytokine Signaling in Immune system |
0.0 | 0.2 | REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION | Genes involved in Antigen processing: Ubiquitination & Proteasome degradation |