Results for NHP6A
Z-value: 0.41
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Transcription factors associated with NHP6A
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
|
NHP6A
|
S000006256 | High-mobility group (HMG) protein, binds to and remodels nucleosomes |
Activity-expression correlation:
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| YGL177W Show fit | 1.06 |
Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data |
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| YKR034W Show fit | 0.91 |
Negative regulator of genes in multiple nitrogen degradation pathways; expression is regulated by nitrogen levels and by Gln3p; member of the GATA-binding family, forms homodimers and heterodimers with Deh1p |
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| YPR169W-A Show fit | 0.84 |
Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps two other dubious ORFs: YPR170C and YPR170W-B |
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| YDR043C Show fit | 0.73 |
Transcriptional repressor that recruits the Cyc8p-Tup1p complex to promoters; mediates glucose repression and negatively regulates a variety of processes including filamentous growth and alkaline pH response |
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| YGR161C Show fit | 0.70 |
Putative component of the protein phosphatase type 2A complex |
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| YLR307C-A Show fit | 0.69 |
Putative protein of unknown function |
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| YJR094C Show fit | 0.63 |
Master regulator of meiosis that is active only during meiotic events, activates transcription of early meiotic genes through interaction with Ume6p, degraded by the 26S proteasome following phosphorylation by Ime2p |
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| YGR039W Show fit | 0.58 |
Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the Autonomously Replicating Sequence ARS722 |
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| YJL149W Show fit | 0.58 |
Putative SCF ubiquitin ligase F-box protein; interacts physically with both Cdc53p and Skp1 and genetically with CDC34; similar to putative F-box protein YDR131C; null mutant suppresses dst1delta sensitivity for 6-azauracil |
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| YJL107C Show fit | 0.54 |
Putative protein of unknown function; expression is induced by activation of the HOG1 mitogen-activated signaling pathway and this induction is Hog1p/Pbs2p dependent; YJL107C and adjacent ORF, YJL108C are merged in related fungi |
Network of associatons between targets according to the STRING database.
First level regulatory network of NHP6A
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 1.2 | GO:0000753 | cell morphogenesis involved in conjugation with cellular fusion(GO:0000753) |
| 0.3 | 1.0 | GO:0090295 | nitrogen catabolite repression of transcription(GO:0090295) |
| 0.2 | 1.0 | GO:0000128 | flocculation(GO:0000128) flocculation via cell wall protein-carbohydrate interaction(GO:0000501) |
| 0.3 | 0.9 | GO:1900460 | negative regulation of invasive growth in response to glucose limitation by negative regulation of transcription from RNA polymerase II promoter(GO:1900460) |
| 0.0 | 0.9 | GO:0051304 | chromosome separation(GO:0051304) |
| 0.1 | 0.8 | GO:0009102 | biotin metabolic process(GO:0006768) biotin biosynthetic process(GO:0009102) |
| 0.2 | 0.7 | GO:0009415 | response to water(GO:0009415) cellular response to water stimulus(GO:0071462) |
| 0.1 | 0.7 | GO:0031146 | SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146) |
| 0.0 | 0.7 | GO:0040020 | regulation of meiotic nuclear division(GO:0040020) |
| 0.0 | 0.7 | GO:0070590 | ascospore wall assembly(GO:0030476) spore wall assembly(GO:0042244) spore wall biogenesis(GO:0070590) ascospore wall biogenesis(GO:0070591) fungal-type cell wall assembly(GO:0071940) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.8 | GO:0000922 | spindle pole(GO:0000922) |
| 0.1 | 0.7 | GO:0005619 | ascospore wall(GO:0005619) |
| 0.1 | 0.7 | GO:0019005 | SCF ubiquitin ligase complex(GO:0019005) |
| 0.0 | 0.6 | GO:0005849 | mRNA cleavage factor complex(GO:0005849) |
| 0.1 | 0.5 | GO:0030915 | Smc5-Smc6 complex(GO:0030915) |
| 0.1 | 0.5 | GO:0000164 | protein phosphatase type 1 complex(GO:0000164) |
| 0.0 | 0.5 | GO:0005779 | integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231) |
| 0.0 | 0.5 | GO:0000932 | cytoplasmic mRNA processing body(GO:0000932) |
| 0.1 | 0.4 | GO:0009331 | glycerol-3-phosphate dehydrogenase complex(GO:0009331) |
| 0.1 | 0.4 | GO:0005960 | glycine cleavage complex(GO:0005960) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 2.1 | GO:0004674 | protein serine/threonine kinase activity(GO:0004674) |
| 0.0 | 2.0 | GO:0001077 | transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077) transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228) |
| 0.0 | 1.1 | GO:0005543 | phospholipid binding(GO:0005543) |
| 0.2 | 0.9 | GO:0000772 | mating pheromone activity(GO:0000772) pheromone activity(GO:0005186) |
| 0.1 | 0.9 | GO:0001103 | RNA polymerase II repressing transcription factor binding(GO:0001103) |
| 0.0 | 0.9 | GO:0000988 | transcription factor activity, protein binding(GO:0000988) |
| 0.0 | 0.8 | GO:0030674 | protein binding, bridging(GO:0030674) |
| 0.0 | 0.8 | GO:0000981 | RNA polymerase II transcription factor activity, sequence-specific DNA binding(GO:0000981) |
| 0.2 | 0.7 | GO:0015603 | siderophore transmembrane transporter activity(GO:0015343) iron chelate transmembrane transporter activity(GO:0015603) siderophore transporter activity(GO:0042927) |
| 0.2 | 0.7 | GO:0005537 | mannose binding(GO:0005537) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 0.9 | PID ERBB4 PATHWAY | ErbB4 signaling events |
| 0.1 | 0.4 | PID E2F PATHWAY | E2F transcription factor network |
| 0.1 | 0.3 | PID INTEGRIN A4B1 PATHWAY | Alpha4 beta1 integrin signaling events |
| 0.0 | 0.2 | PID ERA GENOMIC PATHWAY | Validated nuclear estrogen receptor alpha network |
| 0.0 | 0.2 | PID FANCONI PATHWAY | Fanconi anemia pathway |
| 0.0 | 0.1 | PID FOXO PATHWAY | FoxO family signaling |
| 0.0 | 0.1 | PID ATR PATHWAY | ATR signaling pathway |
| 0.0 | 0.1 | PID PLK1 PATHWAY | PLK1 signaling events |
| 0.0 | 0.0 | NABA ECM REGULATORS | Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 0.8 | REACTOME SHC1 EVENTS IN ERBB4 SIGNALING | Genes involved in SHC1 events in ERBB4 signaling |
| 0.1 | 0.4 | REACTOME CITRIC ACID CYCLE TCA CYCLE | Genes involved in Citric acid cycle (TCA cycle) |
| 0.1 | 0.4 | REACTOME G1 S SPECIFIC TRANSCRIPTION | Genes involved in G1/S-Specific Transcription |
| 0.1 | 0.3 | REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS | Genes involved in Glycerophospholipid biosynthesis |
| 0.1 | 0.2 | REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S | Genes involved in Activation of Chaperone Genes by XBP1(S) |
| 0.0 | 0.2 | REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE | Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase |
| 0.0 | 0.1 | REACTOME MRNA 3 END PROCESSING | Genes involved in mRNA 3'-end processing |
| 0.0 | 0.1 | REACTOME INTEGRIN CELL SURFACE INTERACTIONS | Genes involved in Integrin cell surface interactions |
| 0.0 | 0.1 | REACTOME NUCLEAR SIGNALING BY ERBB4 | Genes involved in Nuclear signaling by ERBB4 |
| 0.0 | 0.1 | REACTOME MEIOTIC RECOMBINATION | Genes involved in Meiotic Recombination |