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Results for HAP2

Z-value: 1.02

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Transcription factors associated with HAP2

Gene Symbol Gene ID Gene Info
HAP2
S000003206 Subunit of the Hap2p/3p/4p/5p CCAAT-binding complex

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HAP2YGL237C-0.481.3e-02Click!

Activity profile of HAP2 motif

Sorted Z-values of HAP2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
YKL096W-A 3.81
CWP2
Covalently linked cell wall mannoprotein, major constituent of the cell wall; plays a role in stabilizing the cell wall; involved in low pH resistance; precursor is GPI-anchored
YNL300W 3.44 Glycosylphosphatidylinositol-dependent cell wall protein, expression is periodic and decreases in respone to ergosterol perturbation or upon entry into stationary phase; depletion increases resistance to lactic acid
YDR044W 3.24
HEM13
Coproporphyrinogen III oxidase, an oxygen requiring enzyme that catalyzes the sixth step in the heme biosynthetic pathway; localizes to the mitochondrial inner membrane; transcription is repressed by oxygen and heme (via Rox1p and Hap1p)
YKR013W 3.22
PRY2
Protein of unknown function, has similarity to Pry1p and Pry3p and to the plant PR-1 class of pathogen related proteins
YFR055W 3.08
IRC7
Putative cystathionine beta-lyase; involved in copper ion homeostasis and sulfur metabolism; null mutant displays increased levels of spontaneous Rad52p foci; expression induced by nitrogen limitation in a GLN3, GAT1-dependent manner
YOR247W 3.02
SRL1
Mannoprotein that exhibits a tight association with the cell wall, required for cell wall stability in the absence of GPI-anchored mannoproteins; has a high serine-threonine content; expression is induced in cell wall mutants
YKR012C 2.84 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified gene PRY2
YDR384C 2.70
ATO3
Plasma membrane protein, regulation pattern suggests a possible role in export of ammonia from the cell; phosphorylated in mitochondria; member of the TC 9.B.33 YaaH family of putative transporters
YGL255W 2.66
ZRT1
High-affinity zinc transporter of the plasma membrane, responsible for the majority of zinc uptake; transcription is induced under low-zinc conditions by the Zap1p transcription factor
YHR181W 2.63
SVP26
Integral membrane protein of the early Golgi apparatus and endoplasmic reticulum, involved in COP II vesicle transport; may also function to promote retention of proteins in the early Golgi compartment
YDR033W 2.55
MRH1
Protein that localizes primarily to the plasma membrane, also found at the nuclear envelope; the authentic, non-tagged protein is detected in mitochondria in a phosphorylated state; has similarity to Hsp30p and Yro2p
YLR110C 2.45
CCW12
Cell wall mannoprotein, mutants are defective in mating and agglutination, expression is downregulated by alpha-factor
YLR349W 2.42 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; overlaps the verified ORF DIC1/YLR348C
YGR159C 2.29
NSR1
Nucleolar protein that binds nuclear localization sequences, required for pre-rRNA processing and ribosome biogenesis
YLR167W 2.23
RPS31
Fusion protein that is cleaved to yield a ribosomal protein of the small (40S) subunit and ubiquitin; ubiquitin may facilitate assembly of the ribosomal protein into ribosomes; interacts genetically with translation factor eIF2B
YBR209W 2.22 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; YBR209W is not an essential gene
YLR348C 2.20
DIC1
Mitochondrial dicarboxylate carrier, integral membrane protein, catalyzes a dicarboxylate-phosphate exchange across the inner mitochondrial membrane, transports cytoplasmic dicarboxylates into the mitochondrial matrix
YFR056C 2.08 Dubious open reading frame unlikely to encode a protein based on available experimental and comparative sequence data; partially overlaps the uncharacterized gene YFR055W
YGL077C 2.02
HNM1
Choline/ethanolamine transporter; involved in the uptake of nitrogen mustard and the uptake of glycine betaine during hypersaline stress; co-regulated with phospholipid biosynthetic genes and negatively regulated by choline and myo-inositol
YML123C 1.92
PHO84
High-affinity inorganic phosphate (Pi) transporter and low-affinity manganese transporter; regulated by Pho4p and Spt7p; mutation confers resistance to arsenate; exit from the ER during maturation requires Pho86p
YHR094C 1.90
HXT1
Low-affinity glucose transporter of the major facilitator superfamily, expression is induced by Hxk2p in the presence of glucose and repressed by Rgt1p when glucose is limiting
YJL158C 1.89
CIS3
Mannose-containing glycoprotein constituent of the cell wall; member of the PIR (proteins with internal repeats) family
YOR011W 1.89
AUS1
Transporter of the ATP-binding cassette family, involved in uptake of sterols and anaerobic growth
YOR315W 1.88
SFG1
Nuclear protein, putative transcription factor required for growth of superficial pseudohyphae (which do not invade the agar substrate) but not for invasive pseudohyphal growth; may act together with Phd1p; potential Cdc28p substrate
YDL055C 1.85
PSA1
GDP-mannose pyrophosphorylase (mannose-1-phosphate guanyltransferase), synthesizes GDP-mannose from GTP and mannose-1-phosphate in cell wall biosynthesis; required for normal cell wall structure
YOL086C 1.80
ADH1
Alcohol dehydrogenase, fermentative isozyme active as homo- or heterotetramers; required for the reduction of acetaldehyde to ethanol, the last step in the glycolytic pathway
YIR021W 1.73
MRS1
Protein required for the splicing of two mitochondrial group I introns (BI3 in COB and AI5beta in COX1); forms a splicing complex, containing four subunits of Mrs1p and two subunits of the BI3-encoded maturase, that binds to the BI3 RNA
YAL038W 1.72
CDC19
Pyruvate kinase, functions as a homotetramer in glycolysis to convert phosphoenolpyruvate to pyruvate, the input for aerobic (TCA cycle) or anaerobic (glucose fermentation) respiration
YDR385W 1.70
EFT2
Elongation factor 2 (EF-2), also encoded by EFT1; catalyzes ribosomal translocation during protein synthesis; contains diphthamide, the unique posttranslationally modified histidine residue specifically ADP-ribosylated by diphtheria toxin
YPL256C 1.62
CLN2
G1 cyclin involved in regulation of the cell cycle; activates Cdc28p kinase to promote the G1 to S phase transition; late G1 specific expression depends on transcription factor complexes, MBF (Swi6p-Mbp1p) and SBF (Swi6p-Swi4p)
YNR016C 1.60
ACC1
Acetyl-CoA carboxylase, biotin containing enzyme that catalyzes the carboxylation of acetyl-CoA to form malonyl-CoA; required for de novo biosynthesis of long-chain fatty acids
YJR094W-A 1.55
RPL43B
Protein component of the large (60S) ribosomal subunit, identical to Rpl43Ap and has similarity to rat L37a ribosomal protein
YPR010C 1.53
RPA135
RNA polymerase I subunit A135
YFL026W 1.53
STE2
Receptor for alpha-factor pheromone; seven transmembrane-domain GPCR that interacts with both pheromone and a heterotrimeric G protein to initiate the signaling response that leads to mating between haploid a and alpha cells
YNL301C 1.53
RPL18B
Protein component of the large (60S) ribosomal subunit, identical to Rpl18Ap and has similarity to rat L18 ribosomal protein
YGR108W 1.49
CLB1
B-type cyclin involved in cell cycle progression; activates Cdc28p to promote the transition from G2 to M phase; accumulates during G2 and M, then targeted via a destruction box motif for ubiquitin-mediated degradation by the proteasome
YPL231W 1.48
FAS2
Alpha subunit of fatty acid synthetase, which catalyzes the synthesis of long-chain saturated fatty acids; contains beta-ketoacyl reductase and beta-ketoacyl synthase activities; phosphorylated
YBR210W 1.46
ERV15
Protein involved in export of proteins from the endoplasmic reticulum, has similarity to Erv14p
YPR170W-B 1.46 Putative protein of unknown function, conserved in fungi; partially overlaps the dubious genes YPR169W-A, YPR170W-A and YRP170C
YBR191W 1.42
RPL21A
Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl21Bp and has similarity to rat L21 ribosomal protein
YBR053C 1.40 Putative protein of unknown function; induced by cell wall perturbation
YGL055W 1.39
OLE1
Delta(9) fatty acid desaturase, required for monounsaturated fatty acid synthesis and for normal distribution of mitochondria
YPR170C 1.39 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the dubious ORFs YPR169W-A and YPR170W-B
YDR534C 1.36
FIT1
Mannoprotein that is incorporated into the cell wall via a glycosylphosphatidylinositol (GPI) anchor, involved in the retention of siderophore-iron in the cell wall
YIL123W 1.32
SIM1
Protein of the SUN family (Sim1p, Uth1p, Nca3p, Sun4p) that may participate in DNA replication, promoter contains SCB regulation box at -300 bp indicating that expression may be cell cycle-regulated
YDR509W 1.31 Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data
YDR037W 1.31
KRS1
Lysyl-tRNA synthetase; also identified as a negative regulator of general control of amino acid biosynthesis
YGL040C 1.31
HEM2
Delta-aminolevulinate dehydratase, a homo-octameric enzyme, catalyzes the conversion of delta-aminolevulinic acid to porphobilinogen, the second step in the heme biosynthetic pathway; localizes to both the cytoplasm and nucleus
YJL190C 1.30
RPS22A
Protein component of the small (40S) ribosomal subunit; nearly identical to Rps22Bp and has similarity to E. coli S8 and rat S15a ribosomal proteins
YOR010C 1.29
TIR2
Putative cell wall mannoprotein of the Srp1p/Tip1p family of serine-alanine-rich proteins; transcription is induced by cold shock and anaerobiosis
YOR176W 1.28
HEM15
Ferrochelatase, a mitochondrial inner membrane protein, catalyzes the insertion of ferrous iron into protoporphyrin IX, the eighth and final step in the heme biosynthetic pathway
YMR320W 1.28 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data
YDR508C 1.27
GNP1
High-affinity glutamine permease, also transports Leu, Ser, Thr, Cys, Met and Asn; expression is fully dependent on Grr1p and modulated by the Ssy1p-Ptr3p-Ssy5p (SPS) sensor of extracellular amino acids
YOR101W 1.26
RAS1
GTPase involved in G-protein signaling in the adenylate cyclase activating pathway, plays a role in cell proliferation; localized to the plasma membrane; homolog of mammalian RAS proto-oncogenes
YKL164C 1.26
PIR1
O-glycosylated protein required for cell wall stability; attached to the cell wall via beta-1,3-glucan; mediates mitochondrial translocation of Apn1p; expression regulated by the cell integrity pathway and by Swi5p during the cell cycle
YCR018C 1.25
SRD1
Protein involved in the processing of pre-rRNA to mature rRNA; contains a C2/C2 zinc finger motif; srd1 mutation suppresses defects caused by the rrp1-1 mutation
YIR020W-A 1.25 Dubious open reading frame unlikely to encode a protein, based on experimental and comparative sequence data
YCL064C 1.23
CHA1
Catabolic L-serine (L-threonine) deaminase, catalyzes the degradation of both L-serine and L-threonine; required to use serine or threonine as the sole nitrogen source, transcriptionally induced by serine and threonine
YOR163W 1.22
DDP1
Polyphosphate phosphatase; hydrolyzes diphosphorylated inositol polyphosphates and diadenosine polyphosphates; has high specificity for diadenosine hexa- and pentaphosphates; member of the MutT family of nucleotide hydrolases
YER124C 1.22
DSE1
Daughter cell-specific protein, may participate in pathways regulating cell wall metabolism; deletion affects cell separation after division and sensitivity to drugs targeted against the cell wall
YAL040C 1.21
CLN3
G1 cyclin involved in cell cycle progression; activates Cdc28p kinase to promote the G1 to S phase transition; plays a role in regulating transcription of the other G1 cyclins, CLN1 and CLN2; regulated by phosphorylation and proteolysis
YNR017W 1.20
TIM23
Essential protein of the mitochondrial inner membrane, component of the mitochondrial import system
YNL178W 1.18
RPS3
Protein component of the small (40S) ribosomal subunit, has apurinic/apyrimidinic (AP) endonuclease activity; essential for viability; has similarity to E. coli S3 and rat S3 ribosomal proteins
YDR112W 1.18
IRC2
Dubious open reading frame, unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps YDR111C; null mutant displays increased levels of spontaneous Rad52p foci
YBR162C 1.17
TOS1
Covalently-bound cell wall protein of unknown function; identified as a cell cycle regulated SBF target gene; deletion mutants are highly resistant to treatment with beta-1,3-glucanase; has sequence similarity to YJL171C
YPL250W-A 1.16 Identified by fungal homology and RT-PCR
YER043C 1.15
SAH1
S-adenosyl-L-homocysteine hydrolase, catabolizes S-adenosyl-L-homocysteine which is formed after donation of the activated methyl group of S-adenosyl-L-methionine (AdoMet) to an acceptor
YIL169C 1.13 Putative protein of unknown function; serine/threonine rich and highly similar to YOL155C, a putative glucan alpha-1,4-glucosidase; transcript is induced in both high and low pH environments; YIL169C is a non-essential gene
YJL026W 1.12
RNR2
Ribonucleotide-diphosphate reductase (RNR), small subunit; the RNR complex catalyzes the rate-limiting step in dNTP synthesis and is regulated by DNA replication and DNA damage checkpoint pathways via localization of the small subunits
YCR075C 1.12
ERS1
Protein with similarity to human cystinosin, which is a H(+)-driven transporter involved in L-cystine export from lysosomes and implicated in the disease cystinosis; contains seven transmembrane domains
YPR063C 1.12 ER-localized protein of unknown function
YLL028W 1.09
TPO1
Polyamine transporter that recognizes spermine, putrescine, and spermidine; catalyzes uptake of polyamines at alkaline pH and excretion at acidic pH; phosphorylation enhances activity and sorting to the plasma membrane
YLR042C 1.09 Protein of unknown function; localizes to the cytoplasm; YLL042C is not an essential gene
YMR106C 1.09
YKU80
Subunit of the telomeric Ku complex (Yku70p-Yku80p), involved in telomere length maintenance, structure and telomere position effect; relocates to sites of double-strand cleavage to promote nonhomologous end joining during DSB repair
YMR038C 1.09
CCS1
Copper chaperone for superoxide dismutase Sod1p, involved in oxidative stress protection; Met-X-Cys-X2-Cys motif within the N-terminal portion is involved in insertion of copper into Sod1p under conditions of copper deprivation
YDR111C 1.08
ALT2
Putative alanine transaminase (glutamic pyruvic transaminase)
YIR020C 1.07 Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data
YCR031C 1.07
RPS14A
Ribosomal protein 59 of the small subunit, required for ribosome assembly and 20S pre-rRNA processing; mutations confer cryptopleurine resistance; nearly identical to Rps14Bp and similar to E. coli S11 and rat S14 ribosomal proteins
YGR040W 1.05
KSS1
Mitogen-activated protein kinase (MAPK) involved in signal transduction pathways that control filamentous growth and pheromone response; the KSS1 gene is nonfunctional in S288C strains and functional in W303 strains
YMR319C 1.05
FET4
Low-affinity Fe(II) transporter of the plasma membrane
YGR259C 1.04 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; overlaps almost completely with the verified ORF TNA1/YGR260W
YJL136C 1.04
RPS21B
Protein component of the small (40S) ribosomal subunit; nearly identical to Rps21Ap and has similarity to rat S21 ribosomal protein
YDR535C 1.04 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; YDR535C is not an essential gene.
YJL198W 1.03
PHO90
Low-affinity phosphate transporter; deletion of pho84, pho87, pho89, pho90, and pho91 causes synthetic lethality; transcription independent of Pi and Pho4p activity; overexpression results in vigorous growth
YDR144C 1.03
MKC7
GPI-anchored aspartyl protease (yapsin) involved in protein processing; shares functions with Yap3p and Kex2p
YHR174W 1.02
ENO2
Enolase II, a phosphopyruvate hydratase that catalyzes the conversion of 2-phosphoglycerate to phosphoenolpyruvate during glycolysis and the reverse reaction during gluconeogenesis; expression is induced in response to glucose
YPR119W 1.02
CLB2
B-type cyclin involved in cell cycle progression; activates Cdc28p to promote the transition from G2 to M phase; accumulates during G2 and M, then targeted via a destruction box motif for ubiquitin-mediated degradation by the proteasome
YNL066W 1.02
SUN4
Cell wall protein related to glucanases, possibly involved in cell wall septation; member of the SUN family
YMR123W 1.02
PKR1
V-ATPase assembly factor, functions with other V-ATPase assembly factors in the ER to efficiently assemble the V-ATPase membrane sector (V0); overproduction confers resistance to Pichia farinosa killer toxin
YPR170W-A 1.01 Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data; identified by expression profiling and mass spectrometry
YER136W 1.00
GDI1
GDP dissociation inhibitor, regulates vesicle traffic in secretory pathways by regulating the dissociation of GDP from the Sec4/Ypt/rab family of GTP binding proteins
YGR251W 0.99 Putative protein of unknown function; deletion mutant has defects in pre-rRNA processing; green fluorescent protein (GFP)-fusion protein localizes to both the nucleus and the nucleolus; YGR251W is an essential gene
YPL163C 0.99
SVS1
Cell wall and vacuolar protein, required for wild-type resistance to vanadate
YLR154C 0.98
RNH203
Ribonuclease H2 subunit, required for RNase H2 activity
YGR148C 0.98
RPL24B
Ribosomal protein L30 of the large (60S) ribosomal subunit, nearly identical to Rpl24Ap and has similarity to rat L24 ribosomal protein; not essential for translation but may be required for normal translation rate
YER019W 0.98
ISC1
Mitochondrial membrane localized inositol phosphosphingolipid phospholipase C, hydrolyzes complex sphingolipids to produce ceramide; activated by phosphatidylserine, cardiolipin, and phosphatidylglycerol; mediates Na+ and Li+ halotolerance
YEL067C 0.96 Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies
YDR309C 0.96
GIC2
Redundant rho-like GTPase Cdc42p effector; homolog of Gic1p; involved in initiation of budding and cellular polarization; interacts with Cdc42p via the Cdc42/Rac-interactive binding (CRIB) domain and with PI(4,5)P2 via a polybasic region
YNR001W-A 0.96 Dubious open reading frame unlikely to encode a functional protein; identified by homology
YDL205C 0.95
HEM3
Phorphobilinogen deaminase, catalyzes the conversion of 4-porphobilinogen to hydroxymethylbilane, the third step in the heme biosynthetic pathway; localizes to both the cytoplasm and nucleus; expression is regulated by Hap2p-Hap3p
YGL030W 0.95
RPL30
Protein component of the large (60S) ribosomal subunit, has similarity to rat L30 ribosomal protein; involved in pre-rRNA processing in the nucleolus; autoregulates splicing of its transcript
YOR175C 0.95
ALE1
Lysophospholipid acyltransferase, partially redundant with Slc1p; part of MBOAT family of membrane-bound O-acyltransferases; key component of Lands cycle; may have role in fatty acid exchange at sn-2 position of mature glycerophospholipids
YGL123W 0.94
RPS2
Protein component of the small (40S) subunit, essential for control of translational accuracy; has similarity to E. coli S5 and rat S2 ribosomal proteins
YLR154W-A 0.94 Dubious open reading frame unlikely to encode a protein; encoded within the the 25S rRNA gene on the opposite strand
YGL039W 0.93 Oxidoreductase, catalyzes NADPH-dependent reduction of the bicyclic diketone bicyclo[2.2.2]octane-2,6-dione (BCO2,6D) to the chiral ketoalcohol (1R,4S,6S)-6-hydroxybicyclo[2.2.2]octane-2-one (BCO2one6ol)
YLR286C 0.91
CTS1
Endochitinase, required for cell separation after mitosis; transcriptional activation during late G and early M cell cycle phases is mediated by transcription factor Ace2p
YER137C 0.90 Putative protein of unknown function
YDL211C 0.90 Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the vacuole
YEL066W 0.89
HPA3
D-Amino acid N-acetyltransferase, catalyzes N-acetylation of D-amino acids through ordered bi-bi mechanism in which acetyl-CoA is first substrate bound and CoA is last product liberated; similar to Hpa2p, acetylates histones weakly in vitro
YGL123C-A 0.89 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; overlaps the verified gene RPS2/YGL123W
YIL029C 0.88 Putative protein of unknown function; deletion confers sensitivity to 4-(N-(S-glutathionylacetyl)amino) phenylarsenoxide (GSAO)
YAR020C 0.88
PAU7
Part of 23-member seripauperin multigene family, active during alcoholic fermentation, regulated by anaerobiosis, inhibited by oxygen, repressed by heme
YBR158W 0.88
AMN1
Protein required for daughter cell separation, multiple mitotic checkpoints, and chromosome stability; contains 12 degenerate leucine-rich repeat motifs; expression is induced by the Mitotic Exit Network (MEN)
YLR130C 0.86
ZRT2
Low-affinity zinc transporter of the plasma membrane; transcription is induced under low-zinc conditions by the Zap1p transcription factor
YDR032C 0.85
PST2
Protein with similarity to members of a family of flavodoxin-like proteins; induced by oxidative stress in a Yap1p dependent manner; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies
YJR009C 0.85
TDH2
Glyceraldehyde-3-phosphate dehydrogenase, isozyme 2, involved in glycolysis and gluconeogenesis; tetramer that catalyzes the reaction of glyceraldehyde-3-phosphate to 1,3 bis-phosphoglycerate; detected in the cytoplasm and cell-wall
YFR031C-A 0.85
RPL2A
Protein component of the large (60S) ribosomal subunit, identical to Rpl2Bp and has similarity to E. coli L2 and rat L8 ribosomal proteins
YOL049W 0.85
GSH2
Glutathione synthetase, catalyzes the ATP-dependent synthesis of glutathione (GSH) from gamma-glutamylcysteine and glycine; induced by oxidative stress and heat shock
YLR190W 0.84
MMR1
Phosphorylated protein of the mitochondrial outer membrane, localizes only to mitochondria of the bud; interacts with Myo2p to mediate mitochondrial distribution to buds; mRNA is targeted to the bud via the transport system involving She2p
YDR344C 0.83 Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data
YER117W 0.83
RPL23B
Protein component of the large (60S) ribosomal subunit, identical to Rpl23Ap and has similarity to E. coli L14 and rat L23 ribosomal proteins
YLR154W-B 0.83 Dubious open reading frame unlikely to encode a protein; encoded within the the 25S rRNA gene on the opposite strand
YCR006C 0.83 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data
YER011W 0.83
TIR1
Cell wall mannoprotein of the Srp1p/Tip1p family of serine-alanine-rich proteins; expression is downregulated at acidic pH and induced by cold shock and anaerobiosis; abundance is increased in cells cultured without shaking
YAL033W 0.82
POP5
Subunit of both RNase MRP, which cleaves pre-rRNA, and nuclear RNase P, which cleaves tRNA precursors to generate mature 5' ends
YLL045C 0.82
RPL8B
Ribosomal protein L4 of the large (60S) ribosomal subunit, nearly identical to Rpl8Ap and has similarity to rat L7a ribosomal protein; mutation results in decreased amounts of free 60S subunits
YNL069C 0.82
RPL16B
N-terminally acetylated protein component of the large (60S) ribosomal subunit, binds to 5.8 S rRNA; has similarity to Rpl16Ap, E. coli L13 and rat L13a ribosomal proteins; transcriptionally regulated by Rap1p
YHR180W 0.81 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data
YER018C 0.81
SPC25
Component of the evolutionarily conserved kinetochore-associated Ndc80 complex (Ndc80p-Nuf2p-Spc24p-Spc25p); involved in chromosome segregation, spindle checkpoint activity and kinetochore clustering
YKL182W 0.80
FAS1
Beta subunit of fatty acid synthetase, which catalyzes the synthesis of long-chain saturated fatty acids; contains acetyltransacylase, dehydratase, enoyl reductase, malonyl transacylase, and palmitoyl transacylase activities
YKL219W 0.80
COS9
Protein of unknown function, member of the DUP380 subfamily of conserved, often subtelomerically-encoded proteins
YDR225W 0.79
HTA1
One of two nearly identical (see also HTA2) histone H2A subtypes; core histone required for chromatin assembly and chromosome function; DNA damage-dependent phosphorylation by Mec1p facilitates DNA repair; acetylated by Nat4p
YKL110C 0.79
KTI12
Protein that plays a role, with Elongator complex, in modification of wobble nucleosides in tRNA; involved in sensitivity to G1 arrest induced by zymocin; interacts with chromatin throughout the genome; also interacts with Cdc19p
YGR050C 0.79 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data
YOL039W 0.79
RPP2A
Ribosomal protein P2 alpha, a component of the ribosomal stalk, which is involved in the interaction between translational elongation factors and the ribosome; regulates the accumulation of P1 (Rpp1Ap and Rpp1Bp) in the cytoplasm
YHR143W 0.78
DSE2
Daughter cell-specific secreted protein with similarity to glucanases, degrades cell wall from the daughter side causing daughter to separate from mother; expression is repressed by cAMP
YOL085C 0.78 Dubious open reading frame unlikely to encode a protein, based on experimental and comparative sequence data; partially overlaps the dubious gene YOL085W-A
YHR005C-A 0.78
MRS11
Essential protein of the mitochondrial intermembrane space, forms a complex with Tim9p (TIM10 complex) that mediates insertion of hydrophobic proteins at the inner membrane, has homology to Mrs5p, which is also involved in this process
YGR052W 0.77
FMP48
Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; induced by treatment with 8-methoxypsoralen and UVA irradiation
YNL046W 0.76 Putative protein of unknown function; expression depends on Swi5p; GFP-fusion protein localizes to the endoplasmic reticulum; deletion confers sensitivity to 4-(N-(S-glutathionylacetyl)amino) phenylarsenoxide (GSAO)
YLR109W 0.76
AHP1
Thiol-specific peroxiredoxin, reduces hydroperoxides to protect against oxidative damage; function in vivo requires covalent conjugation to Urm1p
YBR113W 0.75 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified gene CYC8
YDL241W 0.75 Putative protein of unknown function; YDL241W is not an essential gene
YOR226C 0.75
ISU2
Conserved protein of the mitochondrial matrix, required for synthesis of mitochondrial and cytosolic iron-sulfur proteins, performs a scaffolding function in mitochondria during Fe/S cluster assembly; isu1 isu2 double mutant is inviable
YOR376W-A 0.75 Putative protein of unknown function; identified by fungal homology and RT-PCR
YKR038C 0.74
KAE1
Putative glycoprotease proposed to be in transcription as a component of the EKC protein complex with Bud32p, Cgi121p, Pcc1p, and Gon7p; also identified as a component of the KEOPS protein complex
YIL053W 0.74
RHR2
Constitutively expressed isoform of DL-glycerol-3-phosphatase; involved in glycerol biosynthesis, induced in response to both anaerobic and, along with the Hor2p/Gpp2p isoform, osmotic stress
YJL211C 0.74 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the verified gene YJL210W/PEX2
YER174C 0.74
GRX4
Hydroperoxide and superoxide-radical responsive glutathione-dependent oxidoreductase; monothiol glutaredoxin subfamily member along with Grx3p and Grx5p; protects cells from oxidative damage
YOL085W-A 0.74 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the dubious ORF YOL085C
YBR220C 0.74 Putative protein of unknown function; YBR220C is not an essential gene
YDR098C 0.74
GRX3
Hydroperoxide and superoxide-radical responsive glutathione-dependent oxidoreductase; monothiol glutaredoxin subfamily member along with Grx4p and Grx5p; protects cells from oxidative damage
YHR049W 0.74
FSH1
Serine hydrolase that localizes to both the nucleus and cytoplasm; sequence is similar to Fsh2p and Fsh3p
YOR103C 0.74
OST2
Epsilon subunit of the oligosaccharyltransferase complex of the ER lumen, which catalyzes asparagine-linked glycosylation of newly synthesized proteins
YMR199W 0.73
CLN1
G1 cyclin involved in regulation of the cell cycle; activates Cdc28p kinase to promote the G1 to S phase transition; late G1 specific expression depends on transcription factor complexes, MBF (Swi6p-Mbp1p) and SBF (Swi6p-Swi4p)
YGR187C 0.73
HGH1
Nonessential protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; similar to mammalian BRP16 (Brain protein 16)
YBR249C 0.73
ARO4
3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP) synthase, catalyzes the first step in aromatic amino acid biosynthesis and is feedback-inhibited by tyrosine or high concentrations of phenylalanine or tryptophan
YNR018W 0.73
AIM38
Putative protein of unknown function; non-tagged protein is detected in purified mitochondria; null mutant displays decreased frequency of mitochondrial genome loss (petite formation) and severe growth defect in minimal glycerol media
YLR180W 0.72
SAM1
S-adenosylmethionine synthetase, catalyzes transfer of the adenosyl group of ATP to the sulfur atom of methionine; one of two differentially regulated isozymes (Sam1p and Sam2p)
YLR179C 0.72 Protein of unknown function, transcription is activated by paralogous proteins Yrm1p and Yrr1p along with proteins involved in multidrug resistance; GFP-tagged protein localizes to the cytoplasm and nucleus; YLR179C is not essential
YBR219C 0.71 Putative protein of unknown function; YBR219C is not an essential gene
YEL068C 0.71 Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data
YGL103W 0.70
RPL28
Ribosomal protein of the large (60S) ribosomal subunit, has similarity to E. coli L15 and rat L27a ribosomal proteins; may have peptidyl transferase activity; can mutate to cycloheximide resistance
YML074C 0.70
FPR3
Nucleolar peptidyl-prolyl cis-trans isomerase (PPIase); FK506 binding protein; phosphorylated by casein kinase II (Cka1p-Cka2p-Ckb1p-Ckb2p) and dephosphorylated by Ptp1p
YKL218C 0.70
SRY1
3-hydroxyaspartate dehydratase, deaminates L-threo-3-hydroxyaspartate to form oxaloacetate and ammonia; required for survival in the presence of hydroxyaspartate
YBR067C 0.70
TIP1
Major cell wall mannoprotein with possible lipase activity; transcription is induced by heat- and cold-shock; member of the Srp1p/Tip1p family of serine-alanine-rich proteins
YGR260W 0.70
TNA1
High affinity nicotinic acid plasma membrane permease, responsible for uptake of low levels of nicotinic acid; expression of the gene increases in the absence of extracellular nicotinic acid or para-aminobenzoate (PABA)
YJL167W 0.69
ERG20
Farnesyl pyrophosphate synthetase, has both dimethylallyltranstransferase and geranyltranstransferase activities; catalyzes the formation of C15 farnesyl pyrophosphate units for isoprenoid and sterol biosynthesis
YMR246W 0.68
FAA4
Long chain fatty acyl-CoA synthetase, regulates protein modification during growth in the presence of ethanol, functions to incorporate palmitic acid into phospholipids and neutral lipids
YJL212C 0.67
OPT1
Proton-coupled oligopeptide transporter of the plasma membrane; also transports glutathione and phytochelatin; member of the OPT family
YBR066C 0.67
NRG2
Transcriptional repressor that mediates glucose repression and negatively regulates filamentous growth; has similarity to Nrg1p
YDR518W 0.67
EUG1
Protein disulfide isomerase of the endoplasmic reticulum lumen, function overlaps with that of Pdi1p; may interact with nascent polypeptides in the ER
YGR279C 0.67
SCW4
Cell wall protein with similarity to glucanases; scw4 scw10 double mutants exhibit defects in mating
YDR133C 0.67 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps YDR134C
YFL027C 0.66
GYP8
GTPase-activating protein for yeast Rab family members; Ypt1p is the preferred in vitro substrate but also acts on Sec4p, Ypt31p and Ypt32p; involved in the regulation of ER to Golgi vesicle transport
YGR106C 0.65
VOA1
Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the vacuolar memebrane
YER134C 0.65 Putative protein of unknown function; non-essential gene
YGR214W 0.65
RPS0A
Protein component of the small (40S) ribosomal subunit, nearly identical to Rps0Bp; required for maturation of 18S rRNA along with Rps0Bp; deletion of either RPS0 gene reduces growth rate, deletion of both genes is lethal
YLL044W 0.65 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; transcription of both YLL044W and the overlapping gene RPL8B is reduced in the gcr1 null mutant
YFL037W 0.65
TUB2
Beta-tubulin; associates with alpha-tubulin (Tub1p and Tub3p) to form tubulin dimer, which polymerizes to form microtubules
YPL075W 0.64
GCR1
Transcriptional activator of genes involved in glycolysis; DNA-binding protein that interacts and functions with the transcriptional activator Gcr2p
YPR009W 0.64
SUT2
Putative transcription factor; multicopy suppressor of mutations that cause low activity of the cAMP/protein kinase A pathway; highly similar to Sut1p
YKL081W 0.63
TEF4
Translation elongation factor EF-1 gamma
YER009W 0.63
NTF2
Nuclear envelope protein, interacts with GDP-bound Gsp1p and with proteins of the nuclear pore to transport Gsp1p into the nucleus where it is an essential player in nucleocytoplasmic transport
YER010C 0.63 Protein of unknown function, forms a ring-shaped homotrimer; has similarity to members of the prokaryotic rraA family; possibly involved in a phosphotransfer reaction
YGR086C 0.63
PIL1
Primary component of eisosomes, which are large immobile cell cortex structures associated with endocytosis; null mutants show activation of Pkc1p/Ypk1p stress resistance pathways; detected in phosphorylated state in mitochondria
YER070W 0.63
RNR1
One of two large regulatory subunits of ribonucleotide-diphosphate reductase; the RNR complex catalyzes rate-limiting step in dNTP synthesis, regulated by DNA replication and DNA damage checkpoint pathways via localization of small subunits
YLR150W 0.63
STM1
Protein that binds G4 quadruplex and purine motif triplex nucleic acid; acts with Cdc13p to maintain telomere structure; interacts with ribosomes and subtelomeric Y' DNA; multicopy suppressor of tom1 and pop2 mutations
YML056C 0.62
IMD4
Inosine monophosphate dehydrogenase, catalyzes the first step of GMP biosynthesis, member of a four-gene family in S. cerevisiae, constitutively expressed
YKL187C 0.62 Putative protein of unknown function; the authentic, non-tagged protein is detected in a phosphorylated state in highly purified mitochondria in high-throughput studies
YCL018W 0.62
LEU2
Beta-isopropylmalate dehydrogenase (IMDH), catalyzes the third step in the leucine biosynthesis pathway
YKR092C 0.61
SRP40
Nucleolar, serine-rich protein with a role in preribosome assembly or transport; may function as a chaperone of small nucleolar ribonucleoprotein particles (snoRNPs); immunologically and structurally to rat Nopp140
YGR031W 0.61 Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies
YBR032W 0.61 Dubious open reading frame unlikely to encode a protein, based on experimental and comparative sequence data
YGL076C 0.61
RPL7A
Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl7Bp and has similarity to E. coli L30 and rat L7 ribosomal proteins; contains a conserved C-terminal Nucleic acid Binding Domain (NDB2)
YBR084W 0.61
MIS1
Mitochondrial C1-tetrahydrofolate synthase, involved in interconversion between different oxidation states of tetrahydrofolate (THF); provides activities of formyl-THF synthetase, methenyl-THF cyclohydrolase, and methylene-THF dehydrogenase
YKL212W 0.61
SAC1
Phosphatidylinositol (PI) phosphatase, involved in hydrolysis of PI 3-phosphate, PI 4-phosphate and PI 3,5-bisphosphate to PI; membrane protein localizes to ER and Golgi; involved in protein trafficking, secretion and inositol metabolism
YML027W 0.61
YOX1
Homeodomain-containing transcriptional repressor, binds to Mcm1p and to early cell cycle boxes (ECBs) in the promoters of cell cycle-regulated genes expressed in M/G1 phase; expression is cell cycle-regulated; potential Cdc28p substrate
YDL186W 0.60 Putative protein of unknown function; YDL186W is not an essential gene
YGR055W 0.60
MUP1
High affinity methionine permease, integral membrane protein with 13 putative membrane-spanning regions; also involved in cysteine uptake

Network of associatons between targets according to the STRING database.

First level regulatory network of HAP2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 3.1 GO:0000098 sulfur amino acid catabolic process(GO:0000098)
0.8 5.9 GO:0006782 protoporphyrinogen IX biosynthetic process(GO:0006782) protoporphyrinogen IX metabolic process(GO:0046501)
0.8 2.3 GO:0019673 GDP-mannose biosynthetic process(GO:0009298) GDP-mannose metabolic process(GO:0019673)
0.7 2.6 GO:0098610 agglutination involved in conjugation with cellular fusion(GO:0000752) agglutination involved in conjugation(GO:0000771) heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157) cell-cell adhesion(GO:0098609) adhesion between unicellular organisms(GO:0098610) multi organism cell adhesion(GO:0098740) cell-cell adhesion via plasma-membrane adhesion molecules(GO:0098742)
0.7 2.0 GO:0045901 positive regulation of translational elongation(GO:0045901)
0.6 1.9 GO:0009186 deoxyribonucleoside diphosphate metabolic process(GO:0009186)
0.6 2.2 GO:0035337 fatty-acyl-CoA metabolic process(GO:0035337)
0.5 4.8 GO:0006829 zinc II ion transport(GO:0006829)
0.5 3.1 GO:0072337 modified amino acid transport(GO:0072337)
0.5 2.1 GO:0000461 endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000461)
0.5 1.5 GO:0006567 threonine catabolic process(GO:0006567)
0.5 5.4 GO:0006817 phosphate ion transport(GO:0006817)
0.4 1.3 GO:0006636 unsaturated fatty acid biosynthetic process(GO:0006636) unsaturated fatty acid metabolic process(GO:0033559)
0.4 6.0 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.4 1.3 GO:0007189 adenylate cyclase-activating G-protein coupled receptor signaling pathway(GO:0007189)
0.4 2.0 GO:0006177 GMP biosynthetic process(GO:0006177)
0.4 1.2 GO:0071545 phosphorylated carbohydrate dephosphorylation(GO:0046838) inositol phosphate dephosphorylation(GO:0046855) inositol phosphate catabolic process(GO:0071545)
0.4 1.6 GO:0046500 S-adenosylmethionine metabolic process(GO:0046500)
0.4 1.1 GO:0015848 spermidine transport(GO:0015848)
0.4 2.5 GO:0010696 positive regulation of spindle pole body separation(GO:0010696)
0.3 1.7 GO:0007535 donor selection(GO:0007535)
0.3 1.0 GO:0015680 intracellular copper ion transport(GO:0015680)
0.3 5.3 GO:0006407 rRNA export from nucleus(GO:0006407) rRNA transport(GO:0051029)
0.3 1.0 GO:0030149 sphingolipid catabolic process(GO:0030149) membrane lipid catabolic process(GO:0046466)
0.3 1.3 GO:0070070 proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.3 0.9 GO:0046416 D-amino acid metabolic process(GO:0046416)
0.3 0.6 GO:2000531 regulation of fatty acid biosynthetic process by transcription from RNA polymerase II promoter(GO:0100070) regulation of fatty acid biosynthetic process by regulation of transcription from RNA polymerase II promoter(GO:2000531)
0.3 1.1 GO:0046898 response to organic cyclic compound(GO:0014070) response to cycloheximide(GO:0046898)
0.3 2.0 GO:0009098 leucine biosynthetic process(GO:0009098)
0.3 0.8 GO:0043484 regulation of RNA splicing(GO:0043484) regulation of mRNA splicing, via spliceosome(GO:0048024)
0.3 1.8 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
0.3 5.6 GO:0015918 sterol transport(GO:0015918)
0.3 1.8 GO:0030030 cell projection organization(GO:0030030) cell projection assembly(GO:0030031)
0.2 1.0 GO:0009423 chorismate biosynthetic process(GO:0009423)
0.2 0.2 GO:0035952 regulation of oligopeptide transport by regulation of transcription from RNA polymerase II promoter(GO:0035950) negative regulation of oligopeptide transport by negative regulation of transcription from RNA polymerase II promoter(GO:0035952) regulation of dipeptide transport by regulation of transcription from RNA polymerase II promoter(GO:0035953) negative regulation of dipeptide transport by negative regulation of transcription from RNA polymerase II promoter(GO:0035955) negative regulation of oligopeptide transport(GO:2000877) negative regulation of dipeptide transport(GO:2000879)
0.2 2.6 GO:0007109 obsolete cytokinesis, completion of separation(GO:0007109)
0.2 2.1 GO:0000947 amino acid catabolic process to alcohol via Ehrlich pathway(GO:0000947)
0.2 0.7 GO:0090153 regulation of sphingolipid biosynthetic process(GO:0090153) negative regulation of sphingolipid biosynthetic process(GO:0090155) regulation of membrane lipid metabolic process(GO:1905038)
0.2 0.7 GO:0051083 'de novo' cotranslational protein folding(GO:0051083)
0.2 0.9 GO:0055129 L-proline biosynthetic process(GO:0055129)
0.2 2.3 GO:0045053 protein retention in Golgi apparatus(GO:0045053)
0.2 0.6 GO:0046677 response to antibiotic(GO:0046677)
0.2 1.0 GO:0043433 negative regulation of sequence-specific DNA binding transcription factor activity(GO:0043433)
0.2 0.2 GO:0050685 positive regulation of mRNA processing(GO:0050685)
0.2 1.0 GO:0016114 terpenoid metabolic process(GO:0006721) terpenoid biosynthetic process(GO:0016114) farnesyl diphosphate biosynthetic process(GO:0045337) farnesyl diphosphate metabolic process(GO:0045338)
0.2 0.8 GO:0032878 regulation of establishment or maintenance of cell polarity(GO:0032878)
0.2 0.6 GO:0006624 vacuolar protein processing(GO:0006624)
0.2 0.8 GO:0060277 obsolete negative regulation of transcription involved in G1 phase of mitotic cell cycle(GO:0060277)
0.2 0.6 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.2 0.6 GO:0072363 regulation of glycolytic process by regulation of transcription from RNA polymerase II promoter(GO:0072361) regulation of glycolytic process by positive regulation of transcription from RNA polymerase II promoter(GO:0072363)
0.2 0.2 GO:0042559 folic acid-containing compound biosynthetic process(GO:0009396) pteridine-containing compound biosynthetic process(GO:0042559)
0.2 4.7 GO:0006096 glycolytic process(GO:0006096) ATP generation from ADP(GO:0006757)
0.2 0.9 GO:0046656 folic acid metabolic process(GO:0046655) folic acid biosynthetic process(GO:0046656)
0.2 23.2 GO:0002181 cytoplasmic translation(GO:0002181)
0.2 0.5 GO:0006571 tyrosine biosynthetic process(GO:0006571)
0.2 0.5 GO:0006672 ceramide metabolic process(GO:0006672) ceramide biosynthetic process(GO:0046513)
0.2 1.4 GO:0000321 re-entry into mitotic cell cycle after pheromone arrest(GO:0000321)
0.2 0.2 GO:0019413 acetate biosynthetic process(GO:0019413)
0.2 0.5 GO:0046385 deoxyribonucleoside monophosphate biosynthetic process(GO:0009157) deoxyribonucleoside monophosphate metabolic process(GO:0009162) pyrimidine deoxyribonucleoside monophosphate metabolic process(GO:0009176) pyrimidine deoxyribonucleoside monophosphate biosynthetic process(GO:0009177) pyrimidine deoxyribonucleotide metabolic process(GO:0009219) pyrimidine deoxyribonucleotide biosynthetic process(GO:0009221) 2'-deoxyribonucleotide biosynthetic process(GO:0009265) 2'-deoxyribonucleotide metabolic process(GO:0009394) deoxyribose phosphate biosynthetic process(GO:0046385)
0.2 4.1 GO:0006885 regulation of pH(GO:0006885)
0.2 0.5 GO:0070637 nicotinamide riboside metabolic process(GO:0046495) pyridine nucleoside metabolic process(GO:0070637)
0.2 0.7 GO:0030497 fatty acid elongation(GO:0030497)
0.2 0.7 GO:0035434 copper ion transmembrane transport(GO:0035434)
0.2 0.3 GO:0015909 long-chain fatty acid transport(GO:0015909)
0.2 0.5 GO:0071478 cellular response to radiation(GO:0071478) cellular response to light stimulus(GO:0071482)
0.2 0.6 GO:0009262 deoxyribonucleotide metabolic process(GO:0009262) deoxyribonucleotide biosynthetic process(GO:0009263)
0.2 0.6 GO:0048279 vesicle fusion with endoplasmic reticulum(GO:0048279)
0.2 1.2 GO:0000372 Group I intron splicing(GO:0000372) RNA splicing, via transesterification reactions with guanosine as nucleophile(GO:0000376)
0.2 0.5 GO:0017157 regulation of exocytosis(GO:0017157) regulation of secretion(GO:0051046) regulation of secretion by cell(GO:1903530)
0.1 1.2 GO:0006779 porphyrin-containing compound biosynthetic process(GO:0006779) heme biosynthetic process(GO:0006783) tetrapyrrole biosynthetic process(GO:0033014)
0.1 0.1 GO:0000955 amino acid catabolic process via Ehrlich pathway(GO:0000955)
0.1 0.4 GO:0043171 peptide catabolic process(GO:0043171)
0.1 1.9 GO:0007120 axial cellular bud site selection(GO:0007120)
0.1 0.9 GO:0043555 regulation of translation in response to stress(GO:0043555)
0.1 0.6 GO:0006740 NADPH regeneration(GO:0006740)
0.1 0.3 GO:0000101 sulfur amino acid transport(GO:0000101)
0.1 1.2 GO:0042219 cellular modified amino acid catabolic process(GO:0042219)
0.1 0.4 GO:0070475 rRNA base methylation(GO:0070475)
0.1 0.4 GO:0023021 termination of signal transduction(GO:0023021) termination of G-protein coupled receptor signaling pathway(GO:0038032)
0.1 0.9 GO:0006828 manganese ion transport(GO:0006828)
0.1 2.2 GO:0042790 transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:0042790)
0.1 0.2 GO:0050810 regulation of steroid metabolic process(GO:0019218) regulation of ergosterol biosynthetic process(GO:0032443) regulation of steroid biosynthetic process(GO:0050810)
0.1 2.5 GO:0006633 fatty acid biosynthetic process(GO:0006633)
0.1 1.1 GO:0070525 tRNA threonylcarbamoyladenosine metabolic process(GO:0070525)
0.1 1.4 GO:0033967 box C/D snoRNA metabolic process(GO:0033967) box C/D snoRNA processing(GO:0034963)
0.1 0.6 GO:2000758 positive regulation of histone acetylation(GO:0035066) positive regulation of protein acetylation(GO:1901985) positive regulation of peptidyl-lysine acetylation(GO:2000758)
0.1 0.3 GO:0030048 actin filament-based movement(GO:0030048) actin filament-based transport(GO:0099515)
0.1 0.3 GO:0018216 peptidyl-arginine modification(GO:0018195) peptidyl-arginine methylation(GO:0018216)
0.1 0.5 GO:0006750 glutathione biosynthetic process(GO:0006750) nonribosomal peptide biosynthetic process(GO:0019184)
0.1 0.6 GO:0000920 cell separation after cytokinesis(GO:0000920)
0.1 0.6 GO:0006658 phosphatidylserine metabolic process(GO:0006658)
0.1 2.1 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.1 0.4 GO:0090220 meiotic telomere clustering(GO:0045141) establishment of chromosome localization(GO:0051303) chromosome localization to nuclear envelope involved in homologous chromosome segregation(GO:0090220)
0.1 0.2 GO:0044070 regulation of anion transport(GO:0044070)
0.1 0.4 GO:0035999 tetrahydrofolate interconversion(GO:0035999)
0.1 2.9 GO:0006418 tRNA aminoacylation for protein translation(GO:0006418)
0.1 0.1 GO:0008612 peptidyl-lysine modification to peptidyl-hypusine(GO:0008612)
0.1 0.9 GO:0052803 histidine biosynthetic process(GO:0000105) histidine metabolic process(GO:0006547) imidazole-containing compound metabolic process(GO:0052803)
0.1 0.4 GO:0045048 protein insertion into ER membrane(GO:0045048)
0.1 2.6 GO:0045454 cell redox homeostasis(GO:0045454)
0.1 1.0 GO:0007021 tubulin complex assembly(GO:0007021)
0.1 0.4 GO:0006898 receptor-mediated endocytosis(GO:0006898)
0.1 2.1 GO:0002097 tRNA wobble base modification(GO:0002097) tRNA wobble uridine modification(GO:0002098)
0.1 0.8 GO:0006730 one-carbon metabolic process(GO:0006730)
0.1 0.4 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.1 0.8 GO:0000011 vacuole inheritance(GO:0000011)
0.1 0.6 GO:0009636 response to toxic substance(GO:0009636)
0.1 0.4 GO:0042256 mature ribosome assembly(GO:0042256)
0.1 2.1 GO:0001933 negative regulation of protein phosphorylation(GO:0001933)
0.1 0.3 GO:0008216 spermidine metabolic process(GO:0008216)
0.1 0.1 GO:0090502 RNA phosphodiester bond hydrolysis, endonucleolytic(GO:0090502)
0.1 0.3 GO:0044818 mitotic G2/M transition checkpoint(GO:0044818)
0.1 3.1 GO:0006487 protein N-linked glycosylation(GO:0006487)
0.1 0.7 GO:0006862 nucleotide transport(GO:0006862)
0.1 1.0 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.1 1.5 GO:0042797 tRNA transcription(GO:0009304) tRNA transcription from RNA polymerase III promoter(GO:0042797)
0.1 0.5 GO:0006617 SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition(GO:0006617)
0.1 0.2 GO:0016093 polyprenol metabolic process(GO:0016093) polyprenol biosynthetic process(GO:0016094) dolichol metabolic process(GO:0019348) dolichol biosynthetic process(GO:0019408)
0.1 0.4 GO:0051292 pore complex assembly(GO:0046931) nuclear pore complex assembly(GO:0051292)
0.1 0.2 GO:0036265 RNA (guanine-N7)-methylation(GO:0036265)
0.1 0.2 GO:0034473 U1 snRNA 3'-end processing(GO:0034473)
0.1 0.2 GO:0043097 pyrimidine-containing compound salvage(GO:0008655) pyrimidine ribonucleotide salvage(GO:0010138) pyrimidine nucleotide salvage(GO:0032262) pyrimidine nucleoside salvage(GO:0043097) UMP salvage(GO:0044206)
0.1 0.4 GO:0018344 protein geranylgeranylation(GO:0018344)
0.1 0.2 GO:0002376 immune effector process(GO:0002252) immune system process(GO:0002376) response to virus(GO:0009615) response to external biotic stimulus(GO:0043207) defense response to virus(GO:0051607) response to other organism(GO:0051707) defense response to other organism(GO:0098542)
0.1 0.2 GO:0042992 negative regulation of transcription factor import into nucleus(GO:0042992)
0.1 0.7 GO:0015802 basic amino acid transport(GO:0015802)
0.1 0.2 GO:0045596 negative regulation of cell differentiation(GO:0045596)
0.1 0.3 GO:0007030 Golgi organization(GO:0007030)
0.1 0.4 GO:0015780 nucleotide-sugar transport(GO:0015780)
0.1 0.7 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.1 0.2 GO:0019379 sulfate assimilation, phosphoadenylyl sulfate reduction by phosphoadenylyl-sulfate reductase (thioredoxin)(GO:0019379) sulfate reduction(GO:0019419)
0.1 0.2 GO:0071454 response to anoxia(GO:0034059) cellular response to anoxia(GO:0071454)
0.1 0.2 GO:0019401 glycerol biosynthetic process(GO:0006114) alditol biosynthetic process(GO:0019401)
0.1 0.4 GO:0036228 protein targeting to nuclear inner membrane(GO:0036228)
0.1 0.1 GO:0033239 negative regulation of cellular amine metabolic process(GO:0033239)
0.1 0.1 GO:0090662 energy coupled proton transmembrane transport, against electrochemical gradient(GO:0015988) ATP hydrolysis coupled proton transport(GO:0015991) ATP hydrolysis coupled transmembrane transport(GO:0090662)
0.1 0.2 GO:0048211 Golgi vesicle docking(GO:0048211)
0.1 0.3 GO:0006814 sodium ion transport(GO:0006814)
0.1 0.4 GO:0035268 protein mannosylation(GO:0035268) protein O-linked mannosylation(GO:0035269) mannosylation(GO:0097502)
0.1 0.5 GO:0009312 trehalose biosynthetic process(GO:0005992) oligosaccharide biosynthetic process(GO:0009312) disaccharide biosynthetic process(GO:0046351)
0.1 0.6 GO:0015858 nucleoside transport(GO:0015858)
0.1 0.1 GO:0001015 snoRNA transcription from an RNA polymerase II promoter(GO:0001015)
0.1 0.3 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.1 1.2 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.1 0.3 GO:0070588 calcium ion transmembrane transport(GO:0070588)
0.1 0.2 GO:0051090 regulation of sequence-specific DNA binding transcription factor activity(GO:0051090)
0.1 1.2 GO:0006334 nucleosome assembly(GO:0006334)
0.1 0.7 GO:0015833 peptide transport(GO:0015833)
0.1 0.2 GO:0009090 homoserine biosynthetic process(GO:0009090)
0.1 0.4 GO:0034063 stress granule assembly(GO:0034063)
0.1 0.3 GO:0070481 nuclear-transcribed mRNA catabolic process, non-stop decay(GO:0070481)
0.1 0.7 GO:0006415 translational termination(GO:0006415)
0.1 0.2 GO:0010674 negative regulation of transcription from RNA polymerase II promoter involved in meiotic cell cycle(GO:0010674)
0.1 0.3 GO:1903338 regulation of cell wall organization or biogenesis(GO:1903338)
0.1 0.2 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.1 1.1 GO:0006696 ergosterol biosynthetic process(GO:0006696) phytosteroid biosynthetic process(GO:0016129) cellular alcohol biosynthetic process(GO:0044108) cellular lipid biosynthetic process(GO:0097384)
0.1 0.4 GO:0009164 nucleoside catabolic process(GO:0009164) glycosyl compound catabolic process(GO:1901658)
0.1 1.5 GO:0000472 endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000472)
0.1 0.1 GO:0071466 cellular response to xenobiotic stimulus(GO:0071466)
0.1 1.2 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.1 0.4 GO:0006012 galactose metabolic process(GO:0006012)
0.1 0.3 GO:0009148 pyrimidine nucleoside triphosphate biosynthetic process(GO:0009148)
0.1 0.3 GO:0060304 regulation of phosphatidylinositol dephosphorylation(GO:0060304) endoplasmic reticulum membrane organization(GO:0090158)
0.1 0.1 GO:0071456 cellular response to hypoxia(GO:0071456)
0.1 0.2 GO:0035459 cargo loading into vesicle(GO:0035459) cargo loading into COPII-coated vesicle(GO:0090110)
0.0 0.1 GO:0051469 vesicle fusion with vacuole(GO:0051469)
0.0 0.1 GO:0001676 long-chain fatty acid metabolic process(GO:0001676)
0.0 0.2 GO:0031591 wybutosine metabolic process(GO:0031590) wybutosine biosynthetic process(GO:0031591)
0.0 0.3 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.0 0.7 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413) peptidyl-proline modification(GO:0018208)
0.0 1.0 GO:0048311 mitochondrion inheritance(GO:0000001) mitochondrion distribution(GO:0048311)
0.0 0.0 GO:1902653 secondary alcohol biosynthetic process(GO:1902653)
0.0 0.3 GO:0090114 COPII-coated vesicle budding(GO:0090114)
0.0 1.2 GO:0006414 translational elongation(GO:0006414)
0.0 0.6 GO:0042273 ribosomal large subunit biogenesis(GO:0042273)
0.0 0.8 GO:0030472 mitotic spindle organization in nucleus(GO:0030472)
0.0 0.1 GO:0065005 lipid tube assembly(GO:0060988) protein-lipid complex assembly(GO:0065005) protein-lipid complex subunit organization(GO:0071825)
0.0 0.2 GO:0009099 valine biosynthetic process(GO:0009099)
0.0 0.6 GO:0031125 rRNA 3'-end processing(GO:0031125)
0.0 0.2 GO:0000301 retrograde transport, vesicle recycling within Golgi(GO:0000301)
0.0 0.3 GO:0006749 glutathione metabolic process(GO:0006749)
0.0 5.0 GO:0006364 rRNA processing(GO:0006364)
0.0 0.4 GO:0051320 mitotic S phase(GO:0000084) S phase(GO:0051320)
0.0 0.6 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.0 0.2 GO:0045116 protein neddylation(GO:0045116)
0.0 0.6 GO:0043094 cellular metabolic compound salvage(GO:0043094)
0.0 0.1 GO:0042274 ribosomal small subunit biogenesis(GO:0042274)
0.0 0.2 GO:0006370 7-methylguanosine mRNA capping(GO:0006370)
0.0 0.1 GO:1900436 filamentous growth of a population of unicellular organisms in response to starvation(GO:0036170) regulation of filamentous growth of a population of unicellular organisms in response to starvation(GO:1900434) positive regulation of filamentous growth of a population of unicellular organisms in response to starvation(GO:1900436)
0.0 0.2 GO:0006657 CDP-choline pathway(GO:0006657)
0.0 0.4 GO:0007009 plasma membrane organization(GO:0007009)
0.0 0.5 GO:0030488 tRNA methylation(GO:0030488)
0.0 0.1 GO:0032108 negative regulation of macroautophagy(GO:0016242) negative regulation of response to external stimulus(GO:0032102) negative regulation of response to extracellular stimulus(GO:0032105) negative regulation of response to nutrient levels(GO:0032108)
0.0 0.2 GO:0000162 tryptophan biosynthetic process(GO:0000162) indole-containing compound biosynthetic process(GO:0042435) indolalkylamine biosynthetic process(GO:0046219)
0.0 0.3 GO:0006613 cotranslational protein targeting to membrane(GO:0006613) SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.0 0.4 GO:0006744 ubiquinone metabolic process(GO:0006743) ubiquinone biosynthetic process(GO:0006744) ketone biosynthetic process(GO:0042181) quinone metabolic process(GO:1901661) quinone biosynthetic process(GO:1901663)
0.0 0.1 GO:0006493 protein O-linked glycosylation(GO:0006493)
0.0 0.3 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.0 0.3 GO:0006620 posttranslational protein targeting to membrane(GO:0006620)
0.0 0.5 GO:0000055 ribosomal large subunit export from nucleus(GO:0000055)
0.0 0.3 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0 0.1 GO:0000296 spermine transport(GO:0000296)
0.0 0.3 GO:0015893 drug transport(GO:0015893)
0.0 0.1 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.0 0.1 GO:1904666 negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle(GO:0051436) regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle(GO:0051439) regulation of ubiquitin protein ligase activity(GO:1904666) negative regulation of ubiquitin protein ligase activity(GO:1904667)
0.0 0.1 GO:0060188 regulation of protein desumoylation(GO:0060188)
0.0 0.2 GO:0016574 histone ubiquitination(GO:0016574)
0.0 0.0 GO:0042780 tRNA 3'-end processing(GO:0042780)
0.0 0.1 GO:0046148 pigment biosynthetic process(GO:0046148)
0.0 0.1 GO:0009226 nucleotide-sugar biosynthetic process(GO:0009226)
0.0 0.1 GO:0046174 polyol catabolic process(GO:0046174)
0.0 0.1 GO:0090337 regulation of formin-nucleated actin cable assembly(GO:0090337) positive regulation of formin-nucleated actin cable assembly(GO:0090338)
0.0 0.1 GO:0032239 regulation of mRNA export from nucleus(GO:0010793) regulation of nucleobase-containing compound transport(GO:0032239) regulation of RNA export from nucleus(GO:0046831) regulation of ribonucleoprotein complex localization(GO:2000197)
0.0 0.3 GO:0000917 barrier septum assembly(GO:0000917) cell septum assembly(GO:0090529)
0.0 0.1 GO:0061647 histone H3 acetylation(GO:0043966) histone H3-K9 acetylation(GO:0043970) histone H3-K14 acetylation(GO:0044154) histone H3-K9 modification(GO:0061647)
0.0 0.2 GO:0009395 phospholipid catabolic process(GO:0009395)
0.0 0.3 GO:0010383 cell wall polysaccharide metabolic process(GO:0010383)
0.0 0.1 GO:0034487 amino acid export(GO:0032973) amino acid transmembrane export from vacuole(GO:0032974) vacuolar transmembrane transport(GO:0034486) vacuolar amino acid transmembrane transport(GO:0034487) amino acid transmembrane export(GO:0044746)
0.0 0.1 GO:0070583 spore membrane bending pathway(GO:0070583)
0.0 0.2 GO:0007323 peptide pheromone maturation(GO:0007323)
0.0 1.7 GO:0051169 nucleocytoplasmic transport(GO:0006913) nuclear transport(GO:0051169)
0.0 0.1 GO:0030011 maintenance of cell polarity(GO:0030011)
0.0 0.4 GO:0019740 nitrogen utilization(GO:0019740)
0.0 0.3 GO:0006356 regulation of transcription from RNA polymerase I promoter(GO:0006356)
0.0 0.1 GO:0002943 tRNA dihydrouridine synthesis(GO:0002943)
0.0 0.4 GO:0006506 GPI anchor biosynthetic process(GO:0006506)
0.0 0.2 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.0 0.9 GO:0006888 ER to Golgi vesicle-mediated transport(GO:0006888)
0.0 0.1 GO:0045292 mRNA cis splicing, via spliceosome(GO:0045292)
0.0 0.1 GO:0007232 osmosensory signaling pathway via Sho1 osmosensor(GO:0007232)
0.0 0.1 GO:0015693 magnesium ion transport(GO:0015693)
0.0 0.0 GO:0032233 regulation of actin filament bundle assembly(GO:0032231) positive regulation of actin filament bundle assembly(GO:0032233)
0.0 0.1 GO:0015940 pantothenate metabolic process(GO:0015939) pantothenate biosynthetic process(GO:0015940)
0.0 0.1 GO:0072593 reactive oxygen species metabolic process(GO:0072593)
0.0 0.0 GO:0009416 response to light stimulus(GO:0009416)
0.0 0.1 GO:0006090 pyruvate metabolic process(GO:0006090)
0.0 0.1 GO:0007231 osmosensory signaling pathway(GO:0007231)
0.0 0.1 GO:0051016 regulation of actin filament depolymerization(GO:0030834) negative regulation of actin filament depolymerization(GO:0030835) barbed-end actin filament capping(GO:0051016) actin filament capping(GO:0051693)
0.0 0.1 GO:0044038 cell wall macromolecule biosynthetic process(GO:0044038) cellular component macromolecule biosynthetic process(GO:0070589)
0.0 0.1 GO:0006071 glycerol metabolic process(GO:0006071) alditol metabolic process(GO:0019400)
0.0 0.4 GO:0006896 Golgi to vacuole transport(GO:0006896)
0.0 0.1 GO:0006797 polyphosphate metabolic process(GO:0006797)
0.0 0.0 GO:2001038 cellular response to drug(GO:0035690) regulation of response to drug(GO:2001023) positive regulation of response to drug(GO:2001025) regulation of cellular response to drug(GO:2001038) positive regulation of cellular response to drug(GO:2001040)
0.0 0.1 GO:0006641 neutral lipid metabolic process(GO:0006638) acylglycerol metabolic process(GO:0006639) triglyceride metabolic process(GO:0006641)
0.0 0.0 GO:0016320 endoplasmic reticulum membrane fusion(GO:0016320)
0.0 0.1 GO:0000921 septin ring assembly(GO:0000921)
0.0 0.0 GO:0006816 calcium ion transport(GO:0006816)
0.0 0.0 GO:0006517 protein deglycosylation(GO:0006517)
0.0 0.2 GO:0034243 regulation of transcription elongation from RNA polymerase II promoter(GO:0034243)
0.0 0.1 GO:0032508 DNA duplex unwinding(GO:0032508)
0.0 0.0 GO:0032272 negative regulation of protein polymerization(GO:0032272)
0.0 0.0 GO:2000221 negative regulation of cell growth(GO:0030308) negative regulation of pseudohyphal growth(GO:2000221)
0.0 0.1 GO:0006272 leading strand elongation(GO:0006272)
0.0 0.0 GO:0000103 sulfate assimilation(GO:0000103)
0.0 0.0 GO:0097549 heterochromatin organization involved in chromatin silencing(GO:0070868) chromatin organization involved in negative regulation of transcription(GO:0097549)
0.0 0.0 GO:0071326 cellular glucose homeostasis(GO:0001678) carbohydrate mediated signaling(GO:0009756) hexose mediated signaling(GO:0009757) sugar mediated signaling pathway(GO:0010182) glucose mediated signaling pathway(GO:0010255) carbohydrate homeostasis(GO:0033500) glucose homeostasis(GO:0042593) cellular response to carbohydrate stimulus(GO:0071322) cellular response to monosaccharide stimulus(GO:0071326) cellular response to hexose stimulus(GO:0071331) cellular response to glucose stimulus(GO:0071333)
0.0 0.0 GO:0051329 interphase(GO:0051325) mitotic interphase(GO:0051329)
0.0 0.1 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0 0.2 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.2 GO:0005971 ribonucleoside-diphosphate reductase complex(GO:0005971)
0.5 1.6 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.3 1.0 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.3 8.1 GO:0005887 integral component of plasma membrane(GO:0005887)
0.3 1.5 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.3 16.0 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.3 21.4 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.3 19.5 GO:0005576 extracellular region(GO:0005576)
0.3 0.8 GO:0005827 polar microtubule(GO:0005827) tubulin complex(GO:0045298)
0.2 1.2 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.2 4.1 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.2 1.4 GO:0042597 periplasmic space(GO:0042597)
0.2 3.1 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.2 0.7 GO:0005854 nascent polypeptide-associated complex(GO:0005854)
0.2 1.3 GO:0017059 serine C-palmitoyltransferase complex(GO:0017059) SPOTS complex(GO:0035339)
0.2 1.0 GO:0030689 Noc complex(GO:0030689)
0.2 0.6 GO:0070545 PeBoW complex(GO:0070545)
0.2 6.9 GO:0030134 ER to Golgi transport vesicle(GO:0030134)
0.2 0.5 GO:0017102 methionyl glutamyl tRNA synthetase complex(GO:0017102)
0.2 0.6 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.2 0.9 GO:0000136 alpha-1,6-mannosyltransferase complex(GO:0000136)
0.2 1.8 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.2 0.5 GO:0071261 Ssh1 translocon complex(GO:0071261)
0.1 1.0 GO:0016272 prefoldin complex(GO:0016272)
0.1 1.1 GO:0033101 cellular bud membrane(GO:0033101)
0.1 0.1 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.1 0.7 GO:0030478 actin cap(GO:0030478)
0.1 0.7 GO:0031262 Ndc80 complex(GO:0031262)
0.1 0.9 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.1 0.4 GO:0043529 GET complex(GO:0043529)
0.1 1.0 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.1 0.7 GO:0032126 eisosome(GO:0032126)
0.1 0.3 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.1 0.4 GO:0030869 RENT complex(GO:0030869)
0.1 0.9 GO:0005655 nucleolar ribonuclease P complex(GO:0005655) multimeric ribonuclease P complex(GO:0030681)
0.1 1.4 GO:0000786 nucleosome(GO:0000786)
0.1 0.6 GO:0070772 PAS complex(GO:0070772)
0.1 0.4 GO:0033179 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220) proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.1 0.7 GO:0072686 mitotic spindle(GO:0072686)
0.1 4.0 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.1 0.4 GO:0031502 dolichyl-phosphate-mannose-protein mannosyltransferase complex(GO:0031502)
0.1 2.5 GO:0009277 fungal-type cell wall(GO:0009277)
0.1 0.4 GO:0030123 AP-3 adaptor complex(GO:0030123)
0.1 0.7 GO:0030126 COPI vesicle coat(GO:0030126)
0.1 0.2 GO:0034456 UTP-C complex(GO:0034456)
0.1 0.6 GO:0000346 transcription export complex(GO:0000346)
0.1 0.6 GO:0032432 actin filament bundle(GO:0032432)
0.1 0.3 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.1 0.5 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786) signal recognition particle(GO:0048500)
0.1 0.5 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.1 5.0 GO:0044445 cytosolic part(GO:0044445)
0.1 0.1 GO:0072687 meiotic spindle(GO:0072687)
0.1 0.4 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)
0.1 0.3 GO:0000811 GINS complex(GO:0000811)
0.1 0.5 GO:0042555 MCM complex(GO:0042555)
0.1 0.1 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.1 0.6 GO:0005688 U6 snRNP(GO:0005688)
0.1 0.3 GO:0005797 Golgi medial cisterna(GO:0005797)
0.1 0.6 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.1 0.7 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.1 0.5 GO:0031933 nuclear heterochromatin(GO:0005720) nuclear telomeric heterochromatin(GO:0005724) telomeric heterochromatin(GO:0031933)
0.1 0.3 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.1 0.2 GO:0042729 DASH complex(GO:0042729)
0.1 0.2 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.1 1.1 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.1 0.3 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.1 0.3 GO:0034518 RNA cap binding complex(GO:0034518)
0.1 0.1 GO:0005784 Sec61 translocon complex(GO:0005784)
0.1 0.2 GO:0000229 cytoplasmic chromosome(GO:0000229) mitochondrial chromosome(GO:0000262)
0.1 0.2 GO:0031207 endoplasmic reticulum Sec complex(GO:0031205) Sec62/Sec63 complex(GO:0031207)
0.1 0.2 GO:0033254 vacuolar transporter chaperone complex(GO:0033254)
0.1 0.4 GO:0043527 tRNA methyltransferase complex(GO:0043527)
0.1 1.6 GO:0032040 small-subunit processome(GO:0032040)
0.1 0.2 GO:0055087 Ski complex(GO:0055087)
0.1 0.2 GO:0044284 mitochondrial crista junction(GO:0044284)
0.1 0.4 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.1 0.4 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.1 0.2 GO:0000813 ESCRT I complex(GO:0000813)
0.0 0.2 GO:0000815 ESCRT III complex(GO:0000815)
0.0 0.2 GO:0042788 polysomal ribosome(GO:0042788)
0.0 0.3 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
0.0 0.4 GO:0034399 nuclear periphery(GO:0034399)
0.0 0.5 GO:0044613 nuclear pore central transport channel(GO:0044613)
0.0 6.5 GO:0005730 nucleolus(GO:0005730)
0.0 0.2 GO:0005946 alpha,alpha-trehalose-phosphate synthase complex (UDP-forming)(GO:0005946)
0.0 0.2 GO:0034044 exomer complex(GO:0034044)
0.0 0.3 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0 0.1 GO:0070209 ASTRA complex(GO:0070209)
0.0 0.3 GO:0030008 TRAPP complex(GO:0030008)
0.0 3.9 GO:0005840 ribosome(GO:0005840)
0.0 0.3 GO:0017119 Golgi transport complex(GO:0017119)
0.0 0.1 GO:0097344 Rix1 complex(GO:0097344)
0.0 0.1 GO:0070762 nuclear pore transmembrane ring(GO:0070762)
0.0 0.1 GO:0005884 actin filament(GO:0005884)
0.0 0.1 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.0 0.1 GO:0000938 GARP complex(GO:0000938)
0.0 0.1 GO:0045261 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.0 0.3 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.4 GO:0005844 polysome(GO:0005844)
0.0 0.1 GO:0000328 fungal-type vacuole lumen(GO:0000328) vacuolar lumen(GO:0005775)
0.0 0.2 GO:0016471 vacuolar proton-transporting V-type ATPase complex(GO:0016471) proton-transporting V-type ATPase complex(GO:0033176)
0.0 1.1 GO:0000131 incipient cellular bud site(GO:0000131)
0.0 0.1 GO:0071561 nucleus-vacuole junction(GO:0071561)
0.0 6.2 GO:0005783 endoplasmic reticulum(GO:0005783)
0.0 0.0 GO:0030130 clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.0 0.1 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 2.4 GO:0005759 mitochondrial matrix(GO:0005759)
0.0 0.0 GO:0031105 septin complex(GO:0031105)
0.0 0.1 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 0.1 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.1 GO:0030173 integral component of Golgi membrane(GO:0030173) intrinsic component of Golgi membrane(GO:0031228)
0.0 0.0 GO:0005796 Golgi lumen(GO:0005796)
0.0 0.2 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.0 0.1 GO:0030906 retromer, cargo-selective complex(GO:0030906)
0.0 0.0 GO:0005732 small nucleolar ribonucleoprotein complex(GO:0005732)
0.0 1.0 GO:0005635 nuclear envelope(GO:0005635)
0.0 0.1 GO:0000243 commitment complex(GO:0000243)
0.0 0.1 GO:0005663 DNA replication factor C complex(GO:0005663) Rad17 RFC-like complex(GO:0031389) Elg1 RFC-like complex(GO:0031391)
0.0 0.1 GO:0030894 replisome(GO:0030894) nuclear replisome(GO:0043601)
0.0 0.1 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 3.3 GO:0016634 oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor(GO:0016634)
0.7 4.7 GO:0015665 alcohol transmembrane transporter activity(GO:0015665)
0.7 2.0 GO:0070568 guanylyltransferase activity(GO:0070568)
0.6 6.8 GO:0005199 structural constituent of cell wall(GO:0005199)
0.6 2.2 GO:0005384 manganese ion transmembrane transporter activity(GO:0005384)
0.5 2.2 GO:0061731 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups(GO:0016725) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.5 1.6 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.5 1.5 GO:0008897 holo-[acyl-carrier-protein] synthase activity(GO:0008897)
0.5 2.9 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.5 1.9 GO:0016841 ammonia-lyase activity(GO:0016841)
0.5 2.9 GO:0004022 alcohol dehydrogenase (NAD) activity(GO:0004022)
0.5 1.4 GO:0016717 oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water(GO:0016717)
0.5 1.4 GO:0004930 G-protein coupled receptor activity(GO:0004930)
0.5 3.7 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.4 4.0 GO:0005496 steroid binding(GO:0005496) sterol binding(GO:0032934)
0.4 1.6 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.4 1.1 GO:0015114 phosphate ion transmembrane transporter activity(GO:0015114)
0.3 1.0 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.3 1.0 GO:0043891 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.3 1.0 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.3 1.2 GO:0000297 spermine transmembrane transporter activity(GO:0000297)
0.3 1.3 GO:0000099 sulfur amino acid transmembrane transporter activity(GO:0000099)
0.3 1.9 GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.3 0.8 GO:0004629 phospholipase C activity(GO:0004629)
0.2 1.0 GO:0016531 copper chaperone activity(GO:0016531)
0.2 1.0 GO:0015146 pentose transmembrane transporter activity(GO:0015146)
0.2 1.2 GO:0015173 aromatic amino acid transmembrane transporter activity(GO:0015173)
0.2 1.2 GO:0004707 MAP kinase activity(GO:0004707)
0.2 1.0 GO:1904680 peptide transmembrane transporter activity(GO:1904680)
0.2 6.2 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.2 0.9 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.2 1.2 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.2 3.5 GO:0003746 translation elongation factor activity(GO:0003746)
0.2 1.6 GO:0004551 nucleotide diphosphatase activity(GO:0004551)
0.2 3.1 GO:0001054 RNA polymerase I activity(GO:0001054)
0.2 0.6 GO:0009922 fatty acid elongase activity(GO:0009922)
0.2 0.6 GO:0004488 methylenetetrahydrofolate dehydrogenase (NADP+) activity(GO:0004488)
0.2 1.0 GO:0036002 pre-mRNA binding(GO:0036002)
0.2 0.8 GO:0004467 long-chain fatty acid-CoA ligase activity(GO:0004467)
0.2 1.2 GO:0003906 DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906)
0.2 1.0 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.2 0.6 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.2 1.1 GO:0005375 copper ion transmembrane transporter activity(GO:0005375)
0.2 0.6 GO:0033592 RNA strand annealing activity(GO:0033592) annealing activity(GO:0097617)
0.2 1.8 GO:0031386 protein tag(GO:0031386)
0.2 0.7 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.2 0.8 GO:0016408 C-acyltransferase activity(GO:0016408)
0.2 32.6 GO:0003735 structural constituent of ribosome(GO:0003735)
0.2 0.6 GO:0001055 RNA polymerase II activity(GO:0001055)
0.2 1.3 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.2 0.8 GO:0008536 Ran GTPase binding(GO:0008536)
0.2 0.6 GO:0016832 aldehyde-lyase activity(GO:0016832)
0.2 0.3 GO:0016882 cyclo-ligase activity(GO:0016882)
0.2 0.6 GO:0047429 nucleoside-triphosphate diphosphatase activity(GO:0047429)
0.1 0.6 GO:0016885 ligase activity, forming carbon-carbon bonds(GO:0016885)
0.1 1.1 GO:0004190 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.1 0.5 GO:0004622 lysophospholipase activity(GO:0004622)
0.1 0.4 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.1 0.4 GO:0010521 telomerase inhibitor activity(GO:0010521)
0.1 0.5 GO:0042973 glucan endo-1,3-beta-D-glucosidase activity(GO:0042973)
0.1 0.5 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.1 0.7 GO:0017048 Rho GTPase binding(GO:0017048)
0.1 1.0 GO:0004576 oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.1 0.4 GO:0004338 glucan exo-1,3-beta-glucosidase activity(GO:0004338) beta-glucosidase activity(GO:0008422)
0.1 0.4 GO:0008242 omega peptidase activity(GO:0008242)
0.1 1.1 GO:0016646 oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor(GO:0016646)
0.1 0.5 GO:0009378 four-way junction helicase activity(GO:0009378)
0.1 0.5 GO:0015193 L-proline transmembrane transporter activity(GO:0015193)
0.1 1.6 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.1 1.8 GO:0015926 glucosidase activity(GO:0015926)
0.1 1.2 GO:0005216 ion channel activity(GO:0005216)
0.1 4.3 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765)
0.1 0.4 GO:0000339 RNA cap binding(GO:0000339)
0.1 0.9 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.1 1.1 GO:0000009 alpha-1,6-mannosyltransferase activity(GO:0000009)
0.1 0.3 GO:0016274 arginine N-methyltransferase activity(GO:0016273) protein-arginine N-methyltransferase activity(GO:0016274)
0.1 0.4 GO:0008079 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.1 1.1 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.1 0.6 GO:0008312 7S RNA binding(GO:0008312)
0.1 0.6 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.1 1.8 GO:0016763 transferase activity, transferring pentosyl groups(GO:0016763)
0.1 0.7 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.1 0.2 GO:0004362 glutathione-disulfide reductase activity(GO:0004362)
0.1 0.3 GO:0034596 phosphatidylinositol phosphate 4-phosphatase activity(GO:0034596) phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812)
0.1 1.0 GO:0043495 protein anchor(GO:0043495)
0.1 0.3 GO:0003968 RNA-directed RNA polymerase activity(GO:0003968)
0.1 0.9 GO:0000171 ribonuclease MRP activity(GO:0000171)
0.1 0.3 GO:0070567 cytidylyltransferase activity(GO:0070567)
0.1 0.6 GO:0003756 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.1 0.3 GO:0031370 eukaryotic initiation factor 4G binding(GO:0031370)
0.1 0.5 GO:0080130 L-phenylalanine aminotransferase activity(GO:0070546) L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
0.1 0.4 GO:0008443 phosphofructokinase activity(GO:0008443)
0.1 0.3 GO:0016860 intramolecular oxidoreductase activity(GO:0016860)
0.1 0.3 GO:0016774 phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.1 0.2 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.1 2.0 GO:0015932 nucleobase-containing compound transmembrane transporter activity(GO:0015932)
0.1 0.2 GO:0070300 phosphatidic acid binding(GO:0070300)
0.1 0.2 GO:0016504 peptidase activator activity(GO:0016504)
0.1 0.2 GO:0097027 ubiquitin-protein transferase activator activity(GO:0097027)
0.1 0.8 GO:0030295 protein kinase activator activity(GO:0030295)
0.1 1.6 GO:0042162 telomeric DNA binding(GO:0042162)
0.1 0.6 GO:0016868 intramolecular transferase activity, phosphotransferases(GO:0016868)
0.1 0.7 GO:0001056 RNA polymerase III activity(GO:0001056)
0.1 0.4 GO:0019238 cyclohydrolase activity(GO:0019238)
0.1 0.2 GO:0035591 MAP-kinase scaffold activity(GO:0005078) signaling adaptor activity(GO:0035591)
0.1 2.1 GO:0004812 aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)
0.1 0.4 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.1 0.1 GO:0051185 coenzyme transporter activity(GO:0051185)
0.1 0.5 GO:0004860 protein kinase inhibitor activity(GO:0004860)
0.1 0.2 GO:0050839 cell adhesion molecule binding(GO:0050839)
0.1 0.3 GO:0003923 GPI-anchor transamidase activity(GO:0003923)
0.1 0.3 GO:0008762 UDP-N-acetylmuramate dehydrogenase activity(GO:0008762)
0.1 0.7 GO:0030276 clathrin binding(GO:0030276)
0.1 0.5 GO:0015662 ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism(GO:0015662)
0.1 2.3 GO:0060090 binding, bridging(GO:0060090)
0.1 0.2 GO:0001046 core promoter sequence-specific DNA binding(GO:0001046)
0.1 0.3 GO:0017169 CDP-alcohol phosphatidyltransferase activity(GO:0017169)
0.1 0.4 GO:0016423 tRNA (guanine) methyltransferase activity(GO:0016423)
0.1 3.4 GO:0003924 GTPase activity(GO:0003924)
0.1 0.7 GO:0019843 rRNA binding(GO:0019843)
0.1 1.6 GO:0015631 tubulin binding(GO:0015631)
0.1 0.3 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.1 0.3 GO:0016742 hydroxymethyl-, formyl- and related transferase activity(GO:0016742)
0.1 0.2 GO:0003825 alpha,alpha-trehalose-phosphate synthase (UDP-forming) activity(GO:0003825)
0.1 0.2 GO:0008296 3'-5'-exodeoxyribonuclease activity(GO:0008296)
0.1 0.3 GO:0019201 nucleotide kinase activity(GO:0019201)
0.0 1.5 GO:0046982 protein heterodimerization activity(GO:0046982)
0.0 0.4 GO:0051015 actin filament binding(GO:0051015)
0.0 0.9 GO:0016836 hydro-lyase activity(GO:0016836)
0.0 0.3 GO:0008641 small protein activating enzyme activity(GO:0008641)
0.0 0.2 GO:0051377 mannose-ethanolamine phosphotransferase activity(GO:0051377)
0.0 0.1 GO:0008235 metalloexopeptidase activity(GO:0008235)
0.0 0.1 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.1 GO:0030332 cyclin binding(GO:0030332)
0.0 0.1 GO:0050308 sugar-phosphatase activity(GO:0050308)
0.0 0.3 GO:0003727 single-stranded RNA binding(GO:0003727)
0.0 0.2 GO:0003993 acid phosphatase activity(GO:0003993)
0.0 0.7 GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds(GO:0004553)
0.0 0.1 GO:0003725 double-stranded RNA binding(GO:0003725)
0.0 0.1 GO:0019206 nucleoside kinase activity(GO:0019206)
0.0 0.1 GO:0016854 racemase and epimerase activity(GO:0016854)
0.0 0.5 GO:0005487 nucleocytoplasmic transporter activity(GO:0005487)
0.0 0.2 GO:0042124 glucanosyltransferase activity(GO:0042123) 1,3-beta-glucanosyltransferase activity(GO:0042124)
0.0 0.1 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 0.1 GO:0070336 flap-structured DNA binding(GO:0070336)
0.0 0.4 GO:0050661 NADP binding(GO:0050661)
0.0 0.1 GO:0051219 phosphoprotein binding(GO:0051219)
0.0 0.4 GO:0008320 protein transmembrane transporter activity(GO:0008320) macromolecule transmembrane transporter activity(GO:0022884)
0.0 0.4 GO:0016831 carboxy-lyase activity(GO:0016831)
0.0 0.8 GO:0008135 translation factor activity, RNA binding(GO:0008135)
0.0 0.7 GO:0052689 carboxylic ester hydrolase activity(GO:0052689)
0.0 0.1 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.9 GO:0000287 magnesium ion binding(GO:0000287)
0.0 0.7 GO:0004004 ATP-dependent RNA helicase activity(GO:0004004)
0.0 0.1 GO:0016668 oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor(GO:0016668)
0.0 0.3 GO:0015238 drug transmembrane transporter activity(GO:0015238)
0.0 0.3 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.8 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 0.1 GO:1901681 sulfur compound binding(GO:1901681)
0.0 0.1 GO:0001129 RNA polymerase II transcription factor activity, TBP-class protein binding, involved in preinitiation complex assembly(GO:0001129) RNA polymerase II transcription factor activity, TBP-class protein binding(GO:0001132)
0.0 0.3 GO:0004177 aminopeptidase activity(GO:0004177)
0.0 0.1 GO:0004691 cyclic nucleotide-dependent protein kinase activity(GO:0004690) cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.1 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.0 0.1 GO:0008172 S-methyltransferase activity(GO:0008172)
0.0 0.0 GO:0017070 U6 snRNA binding(GO:0017070)
0.0 0.1 GO:0000033 alpha-1,3-mannosyltransferase activity(GO:0000033)
0.0 0.3 GO:0030515 snoRNA binding(GO:0030515)
0.0 0.1 GO:0004030 aldehyde dehydrogenase (NAD) activity(GO:0004029) aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030)
0.0 0.4 GO:0003779 actin binding(GO:0003779)
0.0 0.6 GO:0016853 isomerase activity(GO:0016853)
0.0 0.3 GO:0001671 ATPase activator activity(GO:0001671)
0.0 0.1 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0 0.6 GO:0008565 protein transporter activity(GO:0008565)
0.0 0.1 GO:0000049 tRNA binding(GO:0000049)
0.0 0.1 GO:0047066 phospholipid-hydroperoxide glutathione peroxidase activity(GO:0047066)
0.0 0.4 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.3 GO:0051087 chaperone binding(GO:0051087)
0.0 0.2 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.0 0.1 GO:0019211 phosphatase activator activity(GO:0019211)
0.0 0.1 GO:0003680 AT DNA binding(GO:0003680)
0.0 0.2 GO:0008175 tRNA methyltransferase activity(GO:0008175)
0.0 0.2 GO:0051536 iron-sulfur cluster binding(GO:0051536) metal cluster binding(GO:0051540)
0.0 0.1 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.1 GO:0000991 transcription factor activity, core RNA polymerase II binding(GO:0000991)
0.0 0.0 GO:0016780 phosphotransferase activity, for other substituted phosphate groups(GO:0016780)
0.0 0.1 GO:0019207 kinase regulator activity(GO:0019207)
0.0 0.0 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.0 0.0 GO:0005034 osmosensor activity(GO:0005034)
0.0 0.2 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 0.0 GO:0005519 cytoskeletal regulatory protein binding(GO:0005519)
0.0 0.0 GO:0019003 GDP binding(GO:0019003)
0.0 0.1 GO:0000026 alpha-1,2-mannosyltransferase activity(GO:0000026)
0.0 0.0 GO:0004601 peroxidase activity(GO:0004601) oxidoreductase activity, acting on peroxide as acceptor(GO:0016684)
0.0 0.1 GO:0033170 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0 0.0 GO:0016530 metallochaperone activity(GO:0016530)
0.0 0.1 GO:0019789 SUMO transferase activity(GO:0019789)
0.0 0.1 GO:0072509 divalent inorganic cation transmembrane transporter activity(GO:0072509)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.2 0.7 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.2 0.8 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.1 0.4 PID SHP2 PATHWAY SHP2 signaling
0.1 0.2 PID AR PATHWAY Coregulation of Androgen receptor activity
0.1 0.2 PID MYC PATHWAY C-MYC pathway
0.1 0.1 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.1 0.1 ST JNK MAPK PATHWAY JNK MAPK Pathway
0.1 0.1 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.1 0.1 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.1 0.2 PID FGF PATHWAY FGF signaling pathway
0.0 0.1 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.0 0.0 PID VEGFR1 PATHWAY VEGFR1 specific signals
0.0 0.0 PID LKB1 PATHWAY LKB1 signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.7 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.4 3.3 REACTOME ACTIVATION OF THE MRNA UPON BINDING OF THE CAP BINDING COMPLEX AND EIFS AND SUBSEQUENT BINDING TO 43S Genes involved in Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S
0.4 1.1 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.3 4.0 REACTOME 3 UTR MEDIATED TRANSLATIONAL REGULATION Genes involved in 3' -UTR-mediated translational regulation
0.2 0.8 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.1 0.4 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.1 0.4 REACTOME SIGNALING BY INSULIN RECEPTOR Genes involved in Signaling by Insulin receptor
0.1 0.1 REACTOME GPCR LIGAND BINDING Genes involved in GPCR ligand binding
0.1 0.8 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.1 0.2 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.1 0.2 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.1 0.4 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.1 0.1 REACTOME DEADENYLATION DEPENDENT MRNA DECAY Genes involved in Deadenylation-dependent mRNA decay
0.0 0.4 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0 0.0 REACTOME PLATELET ACTIVATION SIGNALING AND AGGREGATION Genes involved in Platelet activation, signaling and aggregation
0.0 0.1 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.3 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 0.2 REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.0 0.0 REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS Genes involved in Interactions of Vpr with host cellular proteins
0.0 0.1 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.0 0.0 REACTOME GPCR DOWNSTREAM SIGNALING Genes involved in GPCR downstream signaling
0.0 0.2 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0 0.1 REACTOME POL SWITCHING Genes involved in Polymerase switching
0.0 0.0 REACTOME APC CDC20 MEDIATED DEGRADATION OF NEK2A Genes involved in APC-Cdc20 mediated degradation of Nek2A
0.0 0.3 REACTOME METABOLISM OF LIPIDS AND LIPOPROTEINS Genes involved in Metabolism of lipids and lipoproteins