Results for HAL9
Z-value: 0.73
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Transcription factors associated with HAL9
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
|
HAL9
|
S000005449 | Putative transcription factor containing a zinc finger |
Activity-expression correlation:
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| YJR094W-A Show fit | 5.82 |
Protein component of the large (60S) ribosomal subunit, identical to Rpl43Ap and has similarity to rat L37a ribosomal protein |
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| YHR216W Show fit | 4.74 |
Inosine monophosphate dehydrogenase, catalyzes the first step of GMP biosynthesis, expression is induced by mycophenolic acid resulting in resistance to the drug, expression is repressed by nutrient limitation |
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| YLR154W-A Show fit | 4.58 |
Dubious open reading frame unlikely to encode a protein; encoded within the the 25S rRNA gene on the opposite strand |
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| YLR154W-B Show fit | 4.46 |
Dubious open reading frame unlikely to encode a protein; encoded within the the 25S rRNA gene on the opposite strand |
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| YLR154C Show fit | 4.39 |
Ribonuclease H2 subunit, required for RNase H2 activity |
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| YIR021W Show fit | 4.11 |
Protein required for the splicing of two mitochondrial group I introns (BI3 in COB and AI5beta in COX1); forms a splicing complex, containing four subunits of Mrs1p and two subunits of the BI3-encoded maturase, that binds to the BI3 RNA |
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| YPL250W-A Show fit | 3.98 |
Identified by fungal homology and RT-PCR |
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| YKR092C Show fit | 3.92 |
Nucleolar, serine-rich protein with a role in preribosome assembly or transport; may function as a chaperone of small nucleolar ribonucleoprotein particles (snoRNPs); immunologically and structurally to rat Nopp140 |
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| YLL045C Show fit | 3.61 |
Ribosomal protein L4 of the large (60S) ribosomal subunit, nearly identical to Rpl8Ap and has similarity to rat L7a ribosomal protein; mutation results in decreased amounts of free 60S subunits |
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| YGL209W Show fit | 3.61 |
Protein containing zinc fingers, involved in repression, along with Mig1p, of SUC2 (invertase) expression by high levels of glucose; binds to Mig1p-binding sites in SUC2 promoter |
Network of associatons between targets according to the STRING database.
First level regulatory network of HAL9
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 49.4 | GO:0002181 | cytoplasmic translation(GO:0002181) |
| 0.6 | 6.8 | GO:0006817 | phosphate ion transport(GO:0006817) |
| 1.2 | 4.8 | GO:1900434 | filamentous growth of a population of unicellular organisms in response to starvation(GO:0036170) regulation of filamentous growth of a population of unicellular organisms in response to starvation(GO:1900434) positive regulation of filamentous growth of a population of unicellular organisms in response to starvation(GO:1900436) |
| 1.6 | 4.7 | GO:0006183 | GTP biosynthetic process(GO:0006183) GTP metabolic process(GO:0046039) |
| 0.7 | 4.7 | GO:0043137 | DNA replication, removal of RNA primer(GO:0043137) |
| 1.1 | 4.3 | GO:0000461 | endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000461) |
| 0.5 | 4.1 | GO:0000372 | Group I intron splicing(GO:0000372) RNA splicing, via transesterification reactions with guanosine as nucleophile(GO:0000376) |
| 0.0 | 3.6 | GO:0006913 | nucleocytoplasmic transport(GO:0006913) nuclear transport(GO:0051169) |
| 0.1 | 2.9 | GO:0006418 | tRNA aminoacylation for protein translation(GO:0006418) |
| 0.9 | 2.8 | GO:0007189 | adenylate cyclase-activating G-protein coupled receptor signaling pathway(GO:0007189) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.5 | 38.8 | GO:0022625 | cytosolic large ribosomal subunit(GO:0022625) |
| 0.3 | 18.2 | GO:0022627 | cytosolic small ribosomal subunit(GO:0022627) |
| 0.0 | 8.5 | GO:0005730 | nucleolus(GO:0005730) |
| 1.5 | 4.4 | GO:0032299 | ribonuclease H2 complex(GO:0032299) |
| 0.1 | 3.5 | GO:0005887 | integral component of plasma membrane(GO:0005887) |
| 0.0 | 2.7 | GO:0005840 | ribosome(GO:0005840) |
| 0.2 | 2.4 | GO:0005940 | septin ring(GO:0005940) |
| 0.1 | 2.4 | GO:0070210 | Rpd3L-Expanded complex(GO:0070210) |
| 0.2 | 2.2 | GO:0005736 | DNA-directed RNA polymerase I complex(GO:0005736) |
| 0.2 | 1.7 | GO:0016272 | prefoldin complex(GO:0016272) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 53.4 | GO:0003735 | structural constituent of ribosome(GO:0003735) |
| 0.1 | 6.3 | GO:0003924 | GTPase activity(GO:0003924) |
| 1.6 | 4.7 | GO:0003938 | IMP dehydrogenase activity(GO:0003938) |
| 1.1 | 4.4 | GO:0004523 | RNA-DNA hybrid ribonuclease activity(GO:0004523) |
| 0.3 | 4.3 | GO:0001078 | transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078) |
| 0.5 | 4.2 | GO:0005310 | dicarboxylic acid transmembrane transporter activity(GO:0005310) |
| 0.2 | 3.8 | GO:0004520 | endodeoxyribonuclease activity(GO:0004520) |
| 1.0 | 3.0 | GO:0015114 | phosphate ion transmembrane transporter activity(GO:0015114) |
| 0.1 | 2.9 | GO:0016875 | aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876) |
| 0.9 | 2.8 | GO:0015166 | polyol transmembrane transporter activity(GO:0015166) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.9 | 2.6 | PID SHP2 PATHWAY | SHP2 signaling |
| 0.1 | 1.3 | NABA MATRISOME ASSOCIATED | Ensemble of genes encoding ECM-associated proteins including ECM-affilaited proteins, ECM regulators and secreted factors |
| 0.1 | 0.4 | PID INTEGRIN A4B1 PATHWAY | Alpha4 beta1 integrin signaling events |
| 0.1 | 0.4 | PID UPA UPAR PATHWAY | Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling |
| 0.1 | 0.2 | NABA CORE MATRISOME | Ensemble of genes encoding core extracellular matrix including ECM glycoproteins, collagens and proteoglycans |
| 0.0 | 0.1 | PID MYC PATHWAY | C-MYC pathway |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 4.9 | REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION | Genes involved in Influenza Viral RNA Transcription and Replication |
| 0.4 | 3.5 | REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX | Genes involved in Formation of the ternary complex, and subsequently, the 43S complex |
| 0.9 | 2.6 | REACTOME DOWNSTREAM SIGNALING OF ACTIVATED FGFR | Genes involved in Downstream signaling of activated FGFR |
| 0.6 | 1.7 | REACTOME SULFUR AMINO ACID METABOLISM | Genes involved in Sulfur amino acid metabolism |
| 0.2 | 1.7 | REACTOME UNWINDING OF DNA | Genes involved in Unwinding of DNA |
| 0.2 | 1.3 | REACTOME METABOLISM OF MRNA | Genes involved in Metabolism of mRNA |
| 0.3 | 0.7 | REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS | Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements |
| 0.2 | 0.7 | REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS | Genes involved in Glycerophospholipid biosynthesis |
| 0.1 | 0.4 | REACTOME PEPTIDE LIGAND BINDING RECEPTORS | Genes involved in Peptide ligand-binding receptors |
| 0.1 | 0.3 | REACTOME SHC1 EVENTS IN ERBB4 SIGNALING | Genes involved in SHC1 events in ERBB4 signaling |