Results for GZF3
Z-value: 0.66
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Transcription factors associated with GZF3
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
|
GZF3
|
S000003646 | GATA zinc finger protein |
Activity-expression correlation:
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| YDL210W Show fit | 6.90 |
Permease that serves as a gamma-aminobutyrate (GABA) transport protein involved in the utilization of GABA as a nitrogen source; catalyzes the transport of putrescine and delta-aminolevulinic acid (ALA); localized to the vacuolar membrane |
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| YER065C Show fit | 6.47 |
Isocitrate lyase, catalyzes the formation of succinate and glyoxylate from isocitrate, a key reaction of the glyoxylate cycle; expression of ICL1 is induced by growth on ethanol and repressed by growth on glucose |
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| YKR034W Show fit | 4.88 |
Negative regulator of genes in multiple nitrogen degradation pathways; expression is regulated by nitrogen levels and by Gln3p; member of the GATA-binding family, forms homodimers and heterodimers with Deh1p |
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| YAR050W Show fit | 4.60 |
Lectin-like protein involved in flocculation, cell wall protein that binds to mannose chains on the surface of other cells, confers floc-forming ability that is chymotrypsin sensitive and heat resistant; similar to Flo5p |
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| YIR027C Show fit | 3.84 |
Allantoinase, converts allantoin to allantoate in the first step of allantoin degradation; expression sensitive to nitrogen catabolite repression |
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| YAR047C Show fit | 3.70 |
Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data |
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| YLR296W Show fit | 3.52 |
Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data |
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| YDR343C Show fit | 3.38 |
High-affinity glucose transporter of the major facilitator superfamily, nearly identical to Hxt7p, expressed at high basal levels relative to other HXTs, repression of expression by high glucose requires SNF3 |
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| YLR142W Show fit | 3.30 |
Proline oxidase, nuclear-encoded mitochondrial protein involved in utilization of proline as sole nitrogen source; PUT1 transcription is induced by Put3p in the presence of proline and the absence of a preferred nitrogen source |
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| YNL195C Show fit | 3.25 |
Putative protein of unknown function; shares a promoter with YNL194C; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies |
Network of associatons between targets according to the STRING database.
First level regulatory network of GZF3
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.9 | 7.2 | GO:0006097 | glyoxylate cycle(GO:0006097) |
| 1.8 | 7.1 | GO:0015847 | putrescine transport(GO:0015847) |
| 0.3 | 6.6 | GO:0008645 | hexose transport(GO:0008645) monosaccharide transport(GO:0015749) |
| 1.1 | 6.4 | GO:0000128 | flocculation(GO:0000128) flocculation via cell wall protein-carbohydrate interaction(GO:0000501) |
| 0.9 | 6.2 | GO:0000256 | allantoin metabolic process(GO:0000255) allantoin catabolic process(GO:0000256) |
| 1.7 | 5.1 | GO:0090295 | nitrogen catabolite repression of transcription(GO:0090295) |
| 0.3 | 4.6 | GO:0042724 | thiamine biosynthetic process(GO:0009228) thiamine-containing compound biosynthetic process(GO:0042724) |
| 1.0 | 4.1 | GO:0015804 | neutral amino acid transport(GO:0015804) |
| 0.2 | 3.9 | GO:0005978 | glycogen biosynthetic process(GO:0005978) |
| 0.3 | 3.5 | GO:0019740 | nitrogen utilization(GO:0019740) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 7.3 | GO:0098852 | fungal-type vacuole membrane(GO:0000329) lytic vacuole membrane(GO:0098852) |
| 0.0 | 5.7 | GO:0005886 | plasma membrane(GO:0005886) |
| 0.1 | 4.5 | GO:0005576 | extracellular region(GO:0005576) |
| 0.4 | 3.7 | GO:0000276 | mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276) proton-transporting ATP synthase complex, coupling factor F(o)(GO:0045263) |
| 0.1 | 3.7 | GO:0070469 | respiratory chain(GO:0070469) |
| 0.1 | 3.7 | GO:0042579 | peroxisome(GO:0005777) microbody(GO:0042579) |
| 0.0 | 2.7 | GO:0005743 | mitochondrial inner membrane(GO:0005743) |
| 0.5 | 1.9 | GO:0030287 | cell wall-bounded periplasmic space(GO:0030287) |
| 0.3 | 1.6 | GO:0005771 | multivesicular body(GO:0005771) |
| 0.2 | 1.5 | GO:0000164 | protein phosphatase type 1 complex(GO:0000164) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 10.1 | GO:0000981 | RNA polymerase II transcription factor activity, sequence-specific DNA binding(GO:0000981) |
| 2.5 | 7.6 | GO:0015489 | putrescine transmembrane transporter activity(GO:0015489) |
| 1.7 | 6.7 | GO:0005537 | mannose binding(GO:0005537) |
| 0.4 | 5.7 | GO:0015578 | fructose transmembrane transporter activity(GO:0005353) mannose transmembrane transporter activity(GO:0015578) |
| 0.8 | 5.5 | GO:0016833 | oxo-acid-lyase activity(GO:0016833) |
| 0.4 | 4.1 | GO:0046933 | proton-transporting ATP synthase activity, rotational mechanism(GO:0046933) |
| 0.7 | 4.0 | GO:0016888 | endodeoxyribonuclease activity, producing 5'-phosphomonoesters(GO:0016888) |
| 1.0 | 3.9 | GO:0015193 | L-proline transmembrane transporter activity(GO:0015193) |
| 0.4 | 3.4 | GO:0015294 | solute:cation symporter activity(GO:0015294) |
| 0.3 | 3.4 | GO:0008028 | monocarboxylic acid transmembrane transporter activity(GO:0008028) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 46.4 | PID NFAT 3PATHWAY | Role of Calcineurin-dependent NFAT signaling in lymphocytes |
| 0.4 | 1.2 | PID IL4 2PATHWAY | IL4-mediated signaling events |
| 0.3 | 0.9 | PID HNF3B PATHWAY | FOXA2 and FOXA3 transcription factor networks |
| 0.3 | 0.8 | SA G1 AND S PHASES | Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition. |
| 0.3 | 0.5 | PID EPHA2 FWD PATHWAY | EPHA2 forward signaling |
| 0.1 | 0.5 | PID DELTA NP63 PATHWAY | Validated transcriptional targets of deltaNp63 isoforms |
| 0.1 | 0.5 | PID ERA GENOMIC PATHWAY | Validated nuclear estrogen receptor alpha network |
| 0.1 | 0.3 | PID NOTCH PATHWAY | Notch signaling pathway |
| 0.0 | 0.3 | PID FANCONI PATHWAY | Fanconi anemia pathway |
| 0.1 | 0.2 | PID P38 ALPHA BETA DOWNSTREAM PATHWAY | Signaling mediated by p38-alpha and p38-beta |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 46.3 | REACTOME CHONDROITIN SULFATE BIOSYNTHESIS | Genes involved in Chondroitin sulfate biosynthesis |
| 0.1 | 1.7 | REACTOME DNA REPAIR | Genes involved in DNA Repair |
| 0.2 | 1.6 | REACTOME GLUCONEOGENESIS | Genes involved in Gluconeogenesis |
| 0.2 | 0.5 | REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S | Genes involved in Activation of Chaperone Genes by XBP1(S) |
| 0.2 | 0.4 | REACTOME SHC1 EVENTS IN ERBB4 SIGNALING | Genes involved in SHC1 events in ERBB4 signaling |
| 0.1 | 0.2 | REACTOME NFKB AND MAP KINASES ACTIVATION MEDIATED BY TLR4 SIGNALING REPERTOIRE | Genes involved in NFkB and MAP kinases activation mediated by TLR4 signaling repertoire |
| 0.1 | 0.1 | REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION | Genes involved in NOTCH1 Intracellular Domain Regulates Transcription |
| 0.0 | 0.1 | REACTOME PYRUVATE METABOLISM AND CITRIC ACID TCA CYCLE | Genes involved in Pyruvate metabolism and Citric Acid (TCA) cycle |
| 0.0 | 0.1 | REACTOME INNATE IMMUNE SYSTEM | Genes involved in Innate Immune System |
| 0.0 | 0.1 | REACTOME ETHANOL OXIDATION | Genes involved in Ethanol oxidation |