Results for GAL4
Z-value: 1.44
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Transcription factors associated with GAL4
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
|
GAL4
|
S000006169 | DNA-binding transcription factor required for activating GAL genes |
Activity-expression correlation:
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| YJL045W Show fit | 15.21 |
Minor succinate dehydrogenase isozyme; homologous to Sdh1p, the major isozyme reponsible for the oxidation of succinate and transfer of electrons to ubiquinone; induced during the diauxic shift in a Cat8p-dependent manner |
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| YJR048W Show fit | 7.07 |
Cytochrome c, isoform 1; electron carrier of the mitochondrial intermembrane space that transfers electrons from ubiquinone-cytochrome c oxidoreductase to cytochrome c oxidase during cellular respiration |
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| YOL052C-A Show fit | 6.92 |
Multistress response protein, expression is activated by a variety of xenobiotic agents and environmental or physiological stresses |
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| YBR019C Show fit | 6.74 |
UDP-glucose-4-epimerase, catalyzes the interconversion of UDP-galactose and UDP-D-glucose in galactose metabolism; also catalyzes the conversion of alpha-D-glucose or alpha-D-galactose to their beta-anomers |
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| YOR348C Show fit | 6.46 |
Proline permease, required for high-affinity transport of proline; also transports the toxic proline analog azetidine-2-carboxylate (AzC); PUT4 transcription is repressed in ammonia-grown cells |
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| YNL117W Show fit | 6.30 |
Malate synthase, enzyme of the glyoxylate cycle, involved in utilization of non-fermentable carbon sources; expression is subject to carbon catabolite repression; localizes in peroxisomes during growth in oleic acid medium |
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| YGR067C Show fit | 6.11 |
Putative protein of unknown function; contains a zinc finger motif similar to that of Adr1p |
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| YLR312C Show fit | 6.11 |
Protein of unknown function; null mutant quiescent and non-quiescent cells exhibit reduced reproductive capacity |
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| YMR105C Show fit | 5.81 |
Phosphoglucomutase, catalyzes the conversion from glucose-1-phosphate to glucose-6-phosphate, which is a key step in hexose metabolism; functions as the acceptor for a Glc-phosphotransferase |
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| YGR183C Show fit | 5.60 |
Subunit 9 of the ubiquinol cytochrome-c reductase complex, which is a component of the mitochondrial inner membrane electron transport chain; required for electron transfer at the ubiquinol oxidase site of the complex |
Network of associatons between targets according to the STRING database.
First level regulatory network of GAL4
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 2.2 | 22.3 | GO:0006122 | mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122) |
| 5.2 | 15.6 | GO:0033499 | galactose catabolic process via UDP-galactose(GO:0033499) |
| 0.7 | 14.1 | GO:0015749 | hexose transport(GO:0008645) monosaccharide transport(GO:0015749) |
| 1.0 | 9.1 | GO:0006097 | glyoxylate cycle(GO:0006097) |
| 0.2 | 8.5 | GO:0009060 | aerobic respiration(GO:0009060) |
| 1.6 | 6.5 | GO:0015804 | neutral amino acid transport(GO:0015804) |
| 0.4 | 6.0 | GO:0072593 | reactive oxygen species metabolic process(GO:0072593) |
| 1.9 | 5.8 | GO:0019388 | galactose catabolic process(GO:0019388) |
| 2.3 | 4.6 | GO:0042843 | D-xylose catabolic process(GO:0042843) |
| 0.2 | 4.3 | GO:0006094 | gluconeogenesis(GO:0006094) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.1 | 19.2 | GO:0070469 | respiratory chain(GO:0070469) |
| 0.0 | 13.6 | GO:0005886 | plasma membrane(GO:0005886) |
| 1.4 | 12.6 | GO:0005750 | mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275) |
| 0.9 | 10.9 | GO:0005782 | peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907) |
| 0.0 | 6.2 | GO:0031966 | mitochondrial membrane(GO:0031966) |
| 0.0 | 5.3 | GO:0000324 | storage vacuole(GO:0000322) lytic vacuole(GO:0000323) fungal-type vacuole(GO:0000324) |
| 0.2 | 4.2 | GO:0042645 | nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645) |
| 0.8 | 3.8 | GO:0032221 | Rpd3S complex(GO:0032221) |
| 0.2 | 3.3 | GO:0070847 | core mediator complex(GO:0070847) |
| 0.1 | 2.5 | GO:0005758 | mitochondrial intermembrane space(GO:0005758) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.0 | 16.6 | GO:0046906 | heme binding(GO:0020037) tetrapyrrole binding(GO:0046906) |
| 1.3 | 10.3 | GO:0016679 | ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681) |
| 0.4 | 7.8 | GO:0016831 | carboxy-lyase activity(GO:0016831) |
| 0.6 | 7.1 | GO:0046912 | transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912) |
| 1.6 | 6.4 | GO:0015146 | pentose transmembrane transporter activity(GO:0015146) |
| 1.5 | 5.8 | GO:0004614 | phosphoglucomutase activity(GO:0004614) |
| 1.0 | 5.0 | GO:0015295 | solute:proton symporter activity(GO:0015295) |
| 0.3 | 4.9 | GO:0001010 | transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010) |
| 1.1 | 4.6 | GO:0004032 | alditol:NADP+ 1-oxidoreductase activity(GO:0004032) |
| 0.5 | 4.6 | GO:0005353 | fructose transmembrane transporter activity(GO:0005353) mannose transmembrane transporter activity(GO:0015578) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 66.6 | PID RAS PATHWAY | Regulation of Ras family activation |
| 1.1 | 3.4 | PID HNF3B PATHWAY | FOXA2 and FOXA3 transcription factor networks |
| 0.5 | 1.5 | PID IL4 2PATHWAY | IL4-mediated signaling events |
| 0.4 | 1.2 | PID FOXO PATHWAY | FoxO family signaling |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 66.6 | REACTOME CHONDROITIN SULFATE BIOSYNTHESIS | Genes involved in Chondroitin sulfate biosynthesis |
| 1.1 | 12.5 | REACTOME GLUCOSE METABOLISM | Genes involved in Glucose metabolism |
| 2.4 | 7.1 | REACTOME RESPIRATORY ELECTRON TRANSPORT | Genes involved in Respiratory electron transport |
| 0.3 | 2.4 | REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES | Genes involved in Metabolism of amino acids and derivatives |
| 0.1 | 1.5 | REACTOME DNA REPAIR | Genes involved in DNA Repair |
| 0.0 | 0.2 | REACTOME MEIOTIC RECOMBINATION | Genes involved in Meiotic Recombination |
| 0.1 | 0.1 | REACTOME CITRIC ACID CYCLE TCA CYCLE | Genes involved in Citric acid cycle (TCA cycle) |