Results for FKH2

Z-value: 1.07

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Transcription factors associated with FKH2

Gene Symbol Gene ID Gene Info
S000005012 Forkhead family transcription factor

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot

Activity profile of FKH2 motif

Sorted Z-values of FKH2 motif

Promoter Log-likelihood Transcript Gene Gene Info
YOR315W 11.01 Nuclear protein, putative transcription factor required for growth of superficial pseudohyphae (which do not invade the agar substrate) but not for invasive pseudohyphal growth; may act together with Phd1p; potential Cdc28p substrate
YPR119W 8.54 B-type cyclin involved in cell cycle progression; activates Cdc28p to promote the transition from G2 to M phase; accumulates during G2 and M, then targeted via a destruction box motif for ubiquitin-mediated degradation by the proteasome
YGR108W 7.23 B-type cyclin involved in cell cycle progression; activates Cdc28p to promote the transition from G2 to M phase; accumulates during G2 and M, then targeted via a destruction box motif for ubiquitin-mediated degradation by the proteasome
YOR313C 7.17 Protein whose expression is induced during sporulation; not required for sporulation; heterologous expression in E. coli induces the SOS response that senses DNA damage
YOR314W 5.61 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data
YJR094W-A 4.05 Protein component of the large (60S) ribosomal subunit, identical to Rpl43Ap and has similarity to rat L37a ribosomal protein
YOL127W 3.94 Primary rRNA-binding ribosomal protein component of the large (60S) ribosomal subunit, has similarity to E. coli L23 and rat L23a ribosomal proteins; binds to 26S rRNA via a conserved C-terminal motif
YDR418W 3.91 Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl12Ap; rpl12a rpl12b double mutant exhibits slow growth and slow translation; has similarity to E. coli L11 and rat L12 ribosomal proteins
YIR021W 3.82 Protein required for the splicing of two mitochondrial group I introns (BI3 in COB and AI5beta in COX1); forms a splicing complex, containing four subunits of Mrs1p and two subunits of the BI3-encoded maturase, that binds to the BI3 RNA
YGL021W 3.48 Protein kinase; accumulation and phosphorylation are periodic during the cell cycle; phosphorylated in response to DNA damage; contains characteristic motifs for degradation via the APC pathway; similar to Alk2p and to mammalian haspins
YLR300W 3.31 Major exo-1,3-beta-glucanase of the cell wall, involved in cell wall beta-glucan assembly; exists as three differentially glycosylated isoenzymes
YDR146C 3.31 Transcription factor that activates transcription of genes expressed at the M/G1 phase boundary and in G1 phase; localization to the nucleus occurs during G1 and appears to be regulated by phosphorylation by Cdc28p kinase
YGR040W 3.05 Mitogen-activated protein kinase (MAPK) involved in signal transduction pathways that control filamentous growth and pheromone response; the KSS1 gene is nonfunctional in S288C strains and functional in W303 strains
YFR032C-A 3.00 Protein component of the large (60S) ribosomal subunit, has similarity to rat L29 ribosomal protein; not essential for translation, but required for proper joining of the large and small ribosomal subunits and for normal translation rate
YJR094C 2.92 Master regulator of meiosis that is active only during meiotic events, activates transcription of early meiotic genes through interaction with Ume6p, degraded by the 26S proteasome following phosphorylation by Ime2p
YDL055C 2.75 GDP-mannose pyrophosphorylase (mannose-1-phosphate guanyltransferase), synthesizes GDP-mannose from GTP and mannose-1-phosphate in cell wall biosynthesis; required for normal cell wall structure
YPL141C 2.74 Putative protein kinase; similar to Kin4p; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; YPL141C is not an essential gene
YGL102C 2.72 Dubious open reading frame unlikely to encode a functional protein; overlaps 3' end of essential RPL28 gene encoding a large subunit ribosomal protein
YJL011C 2.68 RNA polymerase III subunit C17; physically interacts with C31, C11, and TFIIIB70; may be involved in the recruitment of pol III by the preinitiation complex
YDR278C 2.66 Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data
YPL250W-A 2.66 Identified by fungal homology and RT-PCR
YMR177W 2.59 Putative metal transporter involved in mitochondrial iron accumulation; closely related to Mmt2p
YJR145C 2.58 Protein component of the small (40S) ribosomal subunit; mutation affects 20S pre-rRNA processing; identical to Rps4Bp and has similarity to rat S4 ribosomal protein
YBL063W 2.54 Kinesin-related motor protein required for mitotic spindle assembly and chromosome segregation; functionally redundant with Cin8p
YOR051C 2.51 Nuclear protein that inhibits replication of Brome mosaic virus in S. cerevisiae, which is a model system for studying replication of positive-strand RNA viruses in their natural hosts
YDL075W 2.50 Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl31Bp and has similarity to rat L31 ribosomal protein; associates with the karyopherin Sxm1p
YOL045W 2.42 One of two (see also PSK1) PAS domain containing S/T protein kinases; regulates sugar flux and translation in response to an unknown metabolite by phosphorylating Ugp1p and Gsy2p (sugar flux) and Caf20p, Tif11p and Sro9p (translation)
YIL009W 2.42 Long chain fatty acyl-CoA synthetase, has a preference for C16 and C18 fatty acids; green fluorescent protein (GFP)-fusion protein localizes to the cell periphery
YDL211C 2.40 Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the vacuole
YLR042C 2.36 Protein of unknown function; localizes to the cytoplasm; YLL042C is not an essential gene
YBR157C 2.28 Protein of unknown function; null mutation does not confer any obvious defects in growth, spore germination, viability, or carbohydrate utilization
YFR032C-B 2.18 Putative protein of unknown function; identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching
YPL051W 2.17 GTPase of the Ras superfamily required to recruit Arl1p to the Golgi; similar to ADP-ribosylation factor
YHR094C 2.06 Low-affinity glucose transporter of the major facilitator superfamily, expression is induced by Hxk2p in the presence of glucose and repressed by Rgt1p when glucose is limiting
YGR195W 2.05 3'-to-5' phosphorolytic exoribonuclease that is a subunit of the exosome; required for 3' processing of the 5.8S rRNA; involved in 3' to 5' mRNA degradation and translation inhibition of non-poly(A) mRNAs
YLR167W 2.05 Fusion protein that is cleaved to yield a ribosomal protein of the small (40S) subunit and ubiquitin; ubiquitin may facilitate assembly of the ribosomal protein into ribosomes; interacts genetically with translation factor eIF2B
YML071C 2.01 Component of the conserved oligomeric Golgi complex (Cog1p through Cog8p), a cytosolic tethering complex that functions in protein trafficking to mediate fusion of transport vesicles to Golgi compartments
YHR172W 2.01 Component of the microtubule-nucleating Tub4p (gamma-tubulin) complex; interacts with Spc110p at the spindle pole body (SPB) inner plaque and with Spc72p at the SPB outer plaque
YDL003W 2.00 Essential protein required for sister chromatid cohesion in mitosis and meiosis; subunit of the cohesin complex; expression is cell cycle regulated and peaks in S phase
YIL131C 1.99 Forkhead family transcription factor with a minor role in the expression of G2/M phase genes; negatively regulates transcriptional elongation; positive role in chromatin silencing at HML and HMR; regulates donor preference during switching
YMR199W 1.97 G1 cyclin involved in regulation of the cell cycle; activates Cdc28p kinase to promote the G1 to S phase transition; late G1 specific expression depends on transcription factor complexes, MBF (Swi6p-Mbp1p) and SBF (Swi6p-Swi4p)
YDR279W 1.96 Ribonuclease H2 subunit, required for RNase H2 activity
YIR019C 1.93 GPI-anchored cell surface glycoprotein (flocculin) required for pseudohyphal formation, invasive growth, flocculation, and biofilms; transcriptionally regulated by the MAPK pathway (via Ste12p and Tec1p) and the cAMP pathway (via Flo8p)
YDR224C 1.92 One of two nearly identical (see HTB2) histone H2B subtypes required for chromatin assembly and chromosome function; Rad6p-Bre1p-Lge1p mediated ubiquitination regulates transcriptional activation, meiotic DSB formation and H3 methylation
YOL123W 1.91 Subunit of cleavage factor I, a five-subunit complex required for the cleavage and polyadenylation of pre-mRNA 3' ends; RRM-containing heteronuclear RNA binding protein and hnRNPA/B family member that binds to poly (A) signal sequences
YMR106C 1.90 Subunit of the telomeric Ku complex (Yku70p-Yku80p), involved in telomere length maintenance, structure and telomere position effect; relocates to sites of double-strand cleavage to promote nonhomologous end joining during DSB repair
YCR097W-A 1.87 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; identified by homology to a hemiascomycetous yeast protein
YBL092W 1.87 Protein component of the large (60S) ribosomal subunit, has similarity to rat L32 ribosomal protein; overexpression disrupts telomeric silencing
YLR333C 1.86 Protein component of the small (40S) ribosomal subunit; nearly identical to Rps25Ap and has similarity to rat S25 ribosomal protein
YKL180W 1.84 Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl17Bp and has similarity to E. coli L22 and rat L17 ribosomal proteins; copurifies with the Dam1 complex (aka DASH complex)
YJL136C 1.83 Protein component of the small (40S) ribosomal subunit; nearly identical to Rps21Ap and has similarity to rat S21 ribosomal protein
YDR147W 1.79 Ethanolamine kinase, primarily responsible for phosphatidylethanolamine synthesis via the CDP-ethanolamine pathway; exhibits some choline kinase activity, thus contributing to phosphatidylcholine synthesis via the CDP-choline pathway
YOR233W 1.78 Serine/threonine protein kinase that inhibits the mitotic exit network (MEN) when the spindle position checkpoint is activated; localized asymmetrically to mother cell cortex, spindle pole body and bud neck
YGR039W 1.75 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the Autonomously Replicating Sequence ARS722
YLR045C 1.75 Microtubule-associated protein (MAP) of the XMAP215/Dis1 family; regulates microtubule dynamics during spindle orientation and metaphase chromosome alignment; interacts with spindle pole body component Spc72p
YBR158W 1.74 Protein required for daughter cell separation, multiple mitotic checkpoints, and chromosome stability; contains 12 degenerate leucine-rich repeat motifs; expression is induced by the Mitotic Exit Network (MEN)
YOR058C 1.73 Mitotic spindle midzone localized microtubule-associated protein (MAP) family member; required for spindle elongation and stabilization; undergoes cell cycle-regulated degradation by anaphase promoting complex; potential Cdc28p substrate
YBL097W 1.73 Essential protein required for chromosome condensation, likely to function as an intrinsic component of the condensation machinery, may influence multiple aspects of chromosome transmission and dynamics
YLR257W 1.72 Putative protein of unknown function
YGL039W 1.72 Oxidoreductase, catalyzes NADPH-dependent reduction of the bicyclic diketone bicyclo[2.2.2]octane-2,6-dione (BCO2,6D) to the chiral ketoalcohol (1R,4S,6S)-6-hydroxybicyclo[2.2.2]octane-2-one (BCO2one6ol)
YMR032W 1.71 Bud neck-localized, SH3 domain-containing protein required for cytokinesis; regulates actomyosin ring dynamics and septin localization; interacts with the formins, Bni1p and Bnr1p, and with Cyk3p, Vrp1p, and Bni5p
YPL116W 1.70 Trichostatin A-insensitive homodimeric histone deacetylase (HDAC) with specificity in vitro for histones H3, H4, H2A, and H2B; similar to Hda1p, Rpd3p, Hos1p, and Hos2p; deletion results in increased histone acetylation at rDNA repeats
YDR113C 1.70 Securin that inhibits anaphase by binding separin Esp1p, also blocks cyclin destruction and mitotic exit, essential for cell cycle arrest in mitosis in the presence of DNA damage or aberrant mitotic spindles; also present in meiotic nuclei
YCR099C 1.68 Putative protein of unknown function
YDL101C 1.67 Cell-cycle checkpoint serine-threonine kinase required for DNA damage-induced transcription of certain target genes, phosphorylation of Rad55p and Sml1p, and transient G2/M arrest after DNA damage; also regulates postreplicative DNA repair
YIL130W 1.65 Proposed transcriptional activator, member of the Gal4p family of zinc cluster proteins
YER074W 1.63 Protein component of the small (40S) ribosomal subunit; identical to Rps24Bp and has similarity to rat S24 ribosomal protein
YAL024C 1.60 Putative GDP/GTP exchange factor required for mitotic exit at low temperatures; acts as a guanine nucleotide exchange factor (GEF) for Tem1p, which is a key regulator of mitotic exit; physically associates with Ras2p-GTP
YBR202W 1.60 Component of the hexameric MCM complex, which is important for priming origins of DNA replication in G1 and becomes an active ATP-dependent helicase that promotes DNA melting and elongation when activated by Cdc7p-Dbf4p in S-phase
YDL228C 1.59 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; almost completely overlaps the verified gene SSB1
YML088W 1.58 F-box receptor protein, subunit of the Skp1-Cdc53-F-box receptor (SCF) E3 ubiquitin ligase complex; binds to phosphorylated Ho endonuclease, allowing its ubiquitylation by SCF and subsequent degradation
YGR188C 1.58 Protein kinase that forms a complex with Mad1p and Bub3p that is crucial in the checkpoint mechanism required to prevent cell cycle progression into anaphase in the presence of spindle damage, associates with centromere DNA via Skp1p
YLR272C 1.58 Non-SMC subunit of the condensin complex (Smc2p-Smc4p-Ycs4p-Brn1p-Ycg1p); required for establishment and maintenance of chromosome condensation, chromosome segregation, chromatin binding of condensin and silencing at the mating type locus
YHL028W 1.57 ER membrane protein involved in the translocation of soluble secretory proteins and insertion of membrane proteins into the ER membrane; may also have a role in the stress response but has only partial functional overlap with WSC1-3
YFR056C 1.55 Dubious open reading frame unlikely to encode a protein based on available experimental and comparative sequence data; partially overlaps the uncharacterized gene YFR055W
YPR077C 1.51 Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data; expression increased by deletion of NAP1
YFR055W 1.51 Putative cystathionine beta-lyase; involved in copper ion homeostasis and sulfur metabolism; null mutant displays increased levels of spontaneous Rad52p foci; expression induced by nitrogen limitation in a GLN3, GAT1-dependent manner
YPL075W 1.51 Transcriptional activator of genes involved in glycolysis; DNA-binding protein that interacts and functions with the transcriptional activator Gcr2p
YPL253C 1.47 Protein that forms a complex with Kar3p at the spindle pole body, possible regulator of Kar3p function in microtubule-mediated processes; required for sister chromatid cohesion; has similarity to Cik1p
YGR179C 1.46 Outer kinetochore protein, required for accurate mitotic chromosome segregation; component of the kinetochore sub-complex COMA (Ctf19p, Okp1p, Mcm21p, Ame1p) that functions as a platform for kinetochore assembly
YER097W 1.44 Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data
YMR119W 1.44 Putative integral membrane E3 ubiquitin ligase; acts with Asi2p and Asi3p to ensure the fidelity of SPS-sensor signalling by maintaining the dormant repressed state of gene expression in the absence of inducing signals
YER180C-A 1.43 Protein interacting with Arl3p, which is a GTPase of the Ras superfamily involved in vesicle-tethering at the Golgi; putative ortholog of human SCOCO
YGR098C 1.39 Separase, a caspase-like cysteine protease that promotes sister chromatid separation by mediating dissociation of the cohesin Scc1p from chromatin; inhibits protein phosphatase 2A-Cdc55p to promote mitotic exit; inhibited by Pds1p
YAL003W 1.38 Translation elongation factor 1 beta; stimulates nucleotide exchange to regenerate EF-1 alpha-GTP for the next elongation cycle; part of the EF-1 complex, which facilitates binding of aminoacyl-tRNA to the ribosomal A site
YOL031C 1.38 Nucleotide exchange factor for the endoplasmic reticulum (ER) lumenal Hsp70 chaperone Kar2p, required for protein translocation into the ER; homolog of Yarrowia lipolytica SLS1; GrpE-like protein
YNL068C 1.36 Forkhead family transcription factor with a major role in the expression of G2/M phase genes; positively regulates transcriptional elongation; negative role in chromatin silencing at HML and HMR; substrate of the Cdc28p/Clb5p kinase
YLR187W 1.36 Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cell periphery, cytoplasm, bud, and bud neck; potential Cdc28p substrate; similar to Caf120p and Skg4p
YOR312C 1.35 Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl20Ap and has similarity to rat L18a ribosomal protein
YGL029W 1.35 Protein involved in nucleolar integrity and processing of the pre-rRNA for the 60S ribosome subunit; transcript is induced in response to cytotoxic stress but not genotoxic stress
YPL242C 1.34 Essential protein required for determination of budding pattern, promotes localization of axial markers Bud4p and Cdc12p and functionally interacts with Sec3p, localizes to the contractile ring during anaphase, member of the IQGAP family
YBL052C 1.33 Histone acetyltransferase catalytic subunit of NuA3 complex that acetylates histone H3, involved in transcriptional silencing; homolog of the mammalian MOZ proto-oncogene; sas3 gcn5 double mutation confers lethality
YGR251W 1.33 Putative protein of unknown function; deletion mutant has defects in pre-rRNA processing; green fluorescent protein (GFP)-fusion protein localizes to both the nucleus and the nucleolus; YGR251W is an essential gene
YLR325C 1.33 Protein component of the large (60S) ribosomal subunit, has similarity to rat L38 ribosomal protein
YJL190C 1.32 Protein component of the small (40S) ribosomal subunit; nearly identical to Rps22Bp and has similarity to E. coli S8 and rat S15a ribosomal proteins
YMR144W 1.32 Putative protein of unknown function; localized to the nucleus; YMR144W is not an essential gene
YLR084C 1.32 N-glycosylated protein involved in the maintenance of bud site selection during bipolar budding; localization requires Rax1p
YER011W 1.30 Cell wall mannoprotein of the Srp1p/Tip1p family of serine-alanine-rich proteins; expression is downregulated at acidic pH and induced by cold shock and anaerobiosis; abundance is increased in cells cultured without shaking
YJR032W 1.29 Peptidyl-prolyl cis-trans isomerase (cyclophilin), catalyzes the cis-trans isomerization of peptide bonds N-terminal to proline residues; binds to Hsp82p and contributes to chaperone activity
YLR367W 1.29 Protein component of the small (40S) ribosomal subunit; nearly identical to Rps22Ap and has similarity to E. coli S8 and rat S15a ribosomal proteins
YPL016W 1.28 Subunit of the SWI/SNF chromatin remodeling complex, which regulates transcription by remodeling chromosomes; required for transcription of many genes, including ADH1, ADH2, GAL1, HO, INO1 and SUC2; can become prion [SWI+]
YLR185W 1.27 Protein component of the large (60S) ribosomal subunit, has similarity to Rpl37Bp and to rat L37 ribosomal protein
YDR259C 1.26 Putative basic leucine zipper (bZIP) transcription factor; overexpression increases sodium and lithium tolerance
YJR092W 1.25 Protein involved in bud-site selection and required for axial budding pattern; localizes with septins to bud neck in mitosis and may constitute an axial landmark for next round of budding; potential Cdc28p substrate
YNR072W 1.25 Hexose transporter, up-regulated in media containing raffinose and galactose at pH 7.7 versus pH 4.7, repressed by high levels of glucose
YOR008C-A 1.24 Putative protein of unknown function, includes a potential transmembrane domain; deletion results in slightly lengthened telomeres
YIR042C 1.24 Putative protein of unknown function; YIR042C is a non-essential gene
YCL014W 1.24 Protein involved in bud-site selection and required for axial budding pattern; localizes with septins to bud neck in mitosis and may constitute an axial landmark for next round of budding
YLR013W 1.23 Protein containing GATA family zinc finger motifs
YIR010W 1.23 Essential component of the MIND kinetochore complex (Mtw1p Including Nnf1p-Nsl1p-Dsn1p) which joins kinetochore subunits contacting DNA to those contacting microtubules; important for chromosome segregation
YJL157C 1.22 Cyclin-dependent kinase inhibitor that mediates cell cycle arrest in response to pheromone; also forms a complex with Cdc24p, Ste4p, and Ste18p that may specify the direction of polarized growth during mating; potential Cdc28p substrate
YBR184W 1.22 Putative protein of unknown function; YBR184W is not an essential gene
YMR198W 1.22 Kinesin-associated protein required for both karyogamy and mitotic spindle organization, interacts stably and specifically with Kar3p and may function to target this kinesin to a specific cellular role; has similarity to Vik1p
YER137C 1.21 Putative protein of unknown function
YFR031C 1.20 Component of the condensin complex, essential SMC chromosomal ATPase family member that forms a complex with Smc4p to form the active ATPase; Smc2p/Smc4p complex binds DNA, possibly in the cleft formed by the coiled-coil of the folded dimer
YJR076C 1.20 Component of the septin ring of the mother-bud neck that is required for cytokinesis; septins recruit proteins to the neck and can act as a barrier to diffusion at the membrane, and they comprise the 10nm filaments seen with EM
YOR326W 1.19 One of two type V myosin motors (along with MYO4) involved in actin-based transport of cargos; required for the polarized delivery of secretory vesicles, the vacuole, late Golgi elements, peroxisomes, and the mitotic spindle
YDR326C 1.16 Protein involved in programmed cell death; mutant shows resistance to cell death induced by amiodarone or intracellular acidification
YLL004W 1.16 Subunit of the origin recognition complex, which directs DNA replication by binding to replication origins and is also involved in transcriptional silencing
YOL124C 1.15 Catalytic subunit of an adoMet-dependent tRNA methyltransferase complex (Trm11p-Trm112p), required for the methylation of the guanosine nucleotide at position 10 (m2G10) in tRNAs; contains a THUMP domain and a methyltransferase domain
YPL227C 1.15 UDP-glucose:dolichyl-phosphate glucosyltransferase, involved in asparagine-linked glycosylation in the endoplasmic reticulum
YBR138C 1.15 Cytoplasmic protein of unknown function, potentially phosphorylated by Cdc28p; YBR138C is not an essential gene
YBL031W 1.15 Cytoskeletal protein of unknown function; overexpression causes growth arrest
YDR025W 1.15 Protein component of the small (40S) ribosomal subunit; identical to Rps11Bp and has similarity to E. coli S17 and rat S11 ribosomal proteins
YIL132C 1.15 Protein required for accurate chromosome segregation during meiosis
YGR140W 1.14 Essential kinetochore protein, component of the CBF3 multisubunit complex that binds to the CDEIII region of the centromere; Cbf2p also binds to the CDEII region possibly forming a different multimeric complex, ubiquitinated in vivo
YNR001W-A 1.14 Dubious open reading frame unlikely to encode a functional protein; identified by homology
YER032W 1.14 Protein involved in 3' mRNA processing, interacts with Ref2p; potential Cdc28p substrate
YGL201C 1.13 Protein involved in DNA replication; component of the Mcm2-7 hexameric complex that binds chromatin as a part of the pre-replicative complex
YPR141C 1.12 Minus-end-directed microtubule motor that functions in mitosis and meiosis, localizes to the spindle pole body and localization is dependent on functional Cik1p, required for nuclear fusion during mating; potential Cdc28p substrate
YHR023W 1.12 Type II myosin heavy chain, required for wild-type cytokinesis and cell separation; localizes to the actomyosin ring; binds to myosin light chains Mlc1p and Mlc2p through its IQ1 and IQ2 motifs respectively
YOR369C 1.12 Protein component of the small (40S) ribosomal subunit; has similarity to rat ribosomal protein S12
YHR180W-A 1.11 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps dubious ORF YHR180C-B and long terminal repeat YHRCsigma3
YBR009C 1.10 One of two identical histone H4 proteins (see also HHF2); core histone required for chromatin assembly and chromosome function; contributes to telomeric silencing; N-terminal domain involved in maintaining genomic integrity
YGL179C 1.10 Protein kinase, related to and functionally redundant with Elm1p and Sak1p for the phosphorylation and activation of Snf1p; functionally orthologous to LKB1, a mammalian kinase associated with Peutz-Jeghers cancer-susceptibility syndrome
YGL103W 1.09 Ribosomal protein of the large (60S) ribosomal subunit, has similarity to E. coli L15 and rat L27a ribosomal proteins; may have peptidyl transferase activity; can mutate to cycloheximide resistance
YHR107C 1.09 Component of the septin ring of the mother-bud neck that is required for cytokinesis; septins recruit proteins to the neck and can act as a barrier to diffusion at the membrane, and they comprise the 10nm filaments seen with EM
YFL022C 1.09 Alpha subunit of cytoplasmic phenylalanyl-tRNA synthetase, forms a tetramer with Frs1p to form active enzyme; evolutionarily distant from mitochondrial phenylalanyl-tRNA synthetase based on protein sequence, but substrate binding is similar
YPL197C 1.06 Dubious open reading frame unlikely to encode a protein, based on experimental and comparative sequence data; partially overlaps the ribosomal gene RPB7B
YLR313C 1.06 Protein involved in shmoo formation and bipolar bud site selection; homologous to Spa2p, localizes to sites of polarized growth in a cell cycle dependent- and Spa2p-dependent manner, interacts with MAPKKs Mkk1p, Mkk2p, and Ste7p
YEL007W 1.06 Putative protein with sequence similarity to S. pombe gti1+ (gluconate transport inducer 1)
YDR157W 1.06 Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data
YLR335W 1.05 Nucleoporin involved in nucleocytoplasmic transport, binds to either the nucleoplasmic or cytoplasmic faces of the nuclear pore complex depending on Ran-GTP levels; also has a role in chromatin organization
YPR157W 1.05 Putative protein of unknown function; induced by treatment with 8-methoxypsoralen and UVA irradiation
YPL226W 1.05 ATP binding cassette family member; Asn/Gln-rich rich region supports [NU+] prion formation, susceptibility to [PSI+] prion induction and aggregation of a fragment of the human Machado-Joseph Disease protein
YBR208C 1.04 Urea amidolyase, contains both urea carboxylase and allophanate hydrolase activities, degrades urea to CO2 and NH3; expression sensitive to nitrogen catabolite repression and induced by allophanate, an intermediate in allantoin degradation
YAL034C-B 1.03 Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data
YMR277W 1.03 Carboxy-terminal domain (CTD) phosphatase, essential for dephosphorylation of the repeated C-terminal domain of the RNA polymerase II large subunit (Rpo21p)
YFR028C 1.03 Protein phosphatase required for mitotic exit; located in the nucleolus until liberated by the FEAR and Mitotic Exit Network in anaphase, enabling it to act on key substrates to effect a decrease in CDK/B-cyclin activity and mitotic exit
YMR102C 1.03 Protein of unknown function; transcription is activated by paralogous transcription factors Yrm1p and Yrr1p along with genes involved in multidrug resistance; mutant shows increased resistance to azoles; YMR102C is not an essential gene
YNL166C 1.03 Protein involved in organization of septins at the mother-bud neck, may interact directly with the Cdc11p septin, localizes to bud neck in a septin-dependent manner
YDL241W 1.02 Putative protein of unknown function; YDL241W is not an essential gene
YJR124C 1.02 Putative protein of unknown function; expression induced under calcium shortage
YBL034C 1.02 Component of the mitotic spindle that binds to interpolar microtubules via its association with beta-tubulin (Tub2p); required for interpolar microtubules to provide an outward force on the spindle poles
YGL177W 1.02 Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data
YGR092W 1.01 Ser/Thr kinase involved in transcription and stress response; functions as part of a network of genes in exit from mitosis; localization is cell cycle regulated; activated by Cdc15p during the exit from mitosis
YBL003C 1.01 One of two nearly identical (see also HTA1) histone H2A subtypes; core histone required for chromatin assembly and chromosome function; DNA damage-dependent phosphorylation by Mec1p facilitates DNA repair; acetylated by Nat4p
YER001W 1.01 Alpha-1,3-mannosyltransferase, integral membrane glycoprotein of the Golgi complex, required for addition of alpha1,3-mannose linkages to N-linked and O-linked oligosaccharides, one of five S. cerevisiae proteins of the MNN1 family
YDR445C 1.01 Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data
YKL096W-A 1.01 Covalently linked cell wall mannoprotein, major constituent of the cell wall; plays a role in stabilizing the cell wall; involved in low pH resistance; precursor is GPI-anchored
YLR455W 1.01 Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the nucleus; deletion confers sensitivity to 4-(N-(S-glutathionylacetyl)amino) phenylarsenoxide (GSAO)
YBR038W 1.00 Chitin synthase II, requires activation from zymogenic form in order to catalyze the transfer of N-acetylglucosamine (GlcNAc) to chitin; required for the synthesis of chitin in the primary septum during cytokinesis
YPL209C 1.00 Aurora kinase involved in regulating kinetochore-microtubule attachments; helps maintain condensed chromosomes during anaphase and early telophase; associates with Sli15p, which promotes Ipl1p association with mitotic spindle
YML005W 1.00 S-adenosylmethionine-dependent methyltransferase of the seven beta-strand family; required for wybutosine formation in phenylalanine-accepting tRNA
YMR015C 0.99 C-22 sterol desaturase, a cytochrome P450 enzyme that catalyzes the formation of the C-22(23) double bond in the sterol side chain in ergosterol biosynthesis; may be a target of azole antifungal drugs
YER073W 0.99 Mitochondrial aldehyde dehydrogenase, involved in regulation or biosynthesis of electron transport chain components and acetate formation; activated by K+; utilizes NADP+ as the preferred coenzyme; constitutively expressed
YHR095W 0.98 Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data
YHL029C 0.98 Cytoplasmic protein required for replication of Brome mosaic virus in S. cerevisiae, which is a model system for studying replication of positive-strand RNA viruses in their natural hosts
YGR229C 0.97 Protein involved in the regulation of cell wall synthesis; proposed to be involved in coordinating cell cycle progression with cell wall integrity
YJR053W 0.97 Component of the GTPase-activating Bfa1p-Bub2p complex involved in multiple cell cycle checkpoint pathways that control exit from mitosis
YBR130C 0.97 Protein that acts as an adaptor between Myo4p and the She2p-mRNA complex; part of the mRNA localization machinery that restricts accumulation of certain proteins to the bud; also required for cortical ER inheritance
YJL183W 0.97 Subunit of a Golgi mannosyltransferase complex that also contains Anp1p, Mnn9p, Mnn10p, and Hoc1p, and mediates elongation of the polysaccharide mannan backbone; has homology to Mnn10p
YAL034W-A 0.96 Essential component of the MIND kinetochore complex (Mtw1p Including Nnf1p-Nsl1p-Dsn1p) which joins kinetochore subunits contacting DNA to those contacting microtubules; critical to kinetochore assembly
YLR301W 0.96 Protein of unknown function that interacts with Sec72p
YKR092C 0.96 Nucleolar, serine-rich protein with a role in preribosome assembly or transport; may function as a chaperone of small nucleolar ribonucleoprotein particles (snoRNPs); immunologically and structurally to rat Nopp140
YAR018C 0.96 Nonessential protein kinase with unknown cellular role
YCL063W 0.96 Protein involved in vacuole inheritance; acts as a vacuole-specific receptor for myosin Myo2p
YMR290W-A 0.96 Dubious open reading frame unlikely to encode a functional protein, based on available experimental and comparative sequence data; overlaps 5' end of essential HAS1 gene which encodes an ATP-dependent RNA helicase
YML053C 0.95 Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and the nucleus; YML053C is not an essential gene
YGL209W 0.94 Protein containing zinc fingers, involved in repression, along with Mig1p, of SUC2 (invertase) expression by high levels of glucose; binds to Mig1p-binding sites in SUC2 promoter
YDL240W 0.94 Putative GTPase-activating protein (GAP) involved in the Pkc1p-mediated signaling pathway that controls cell wall integrity; appears to specifically regulate 1,3-beta-glucan synthesis
YDL047W 0.94 Type 2A-related serine-threonine phosphatase that functions in the G1/S transition of the mitotic cycle; cytoplasmic and nuclear protein that modulates functions mediated by Pkc1p including cell wall and actin cytoskeleton organization
YMR100W 0.93 Protein of unknown function, deletion causes multi-budding phenotype; has similarity to Aspergillus nidulans samB gene
YEL061C 0.93 Kinesin motor protein involved in mitotic spindle assembly and chromosome segregation
YGL089C 0.92 Mating pheromone alpha-factor, made by alpha cells; interacts with mating type a cells to induce cell cycle arrest and other responses leading to mating; also encoded by MF(ALPHA)1, which is more highly expressed than MF(ALPHA)2
YDR447C 0.92 Ribosomal protein 51 (rp51) of the small (40s) subunit; nearly identical to Rps17Ap and has similarity to rat S17 ribosomal protein
YGL070C 0.91 RNA polymerase II subunit B12.6; contacts DNA; mutations affect transcription start site; involved in telomere maintenance
YDR500C 0.90 Protein component of the large (60S) ribosomal subunit, has similarity to Rpl37Ap and to rat L37 ribosomal protein
YDL056W 0.90 Transcription factor involved in regulation of cell cycle progression from G1 to S phase, forms a complex with Swi6p that binds to MluI cell cycle box regulatory element in promoters of DNA synthesis genes
YBR092C 0.90 Constitutively expressed acid phosphatase similar to Pho5p; brought to the cell surface by transport vesicles; hydrolyzes thiamin phosphates in the periplasmic space, increasing cellular thiamin uptake; expression is repressed by thiamin
YPL032C 0.90 Protein of unknown function, mutant phenotype suggests a potential role in vacuolar function; green fluorescent protein (GFP)-fusion protein localizes to the cell periphery, cytoplasm, bud, and bud neck
YNR062C 0.89 Putative membrane protein of unknown function
YKR041W 0.89 Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus
YBR112C 0.89 General transcriptional co-repressor, acts together with Tup1p; also acts as part of a transcriptional co-activator complex that recruits the SWI/SNF and SAGA complexes to promoters
YHR169W 0.89 Putative ATP-dependent RNA helicase of the DEAD-box family involved in biogenesis of the 40S ribosomal subunit
YGL101W 0.88 Putative protein of unknown function; non-essential gene with similarity to YBR242W; interacts with the DNA helicase Hpr5p
YBL009W 0.88 Protein kinase; accumulation and phosphorylation are periodic during the cell cycle; phosphorylated in response to DNA damage; contains characteristic motifs for degradation via the APC pathway; similar to Alk1p and to mammalian haspins
YKR010C 0.88 Nonessential mitochondrial protein of unknown function with sequence similarity to Net1p; identified as a topoisomerase I (Top1p) binding protein; displays synthetic genetic interactions with TOP1 and HPR1
YBR156C 0.88 Subunit of the Ipl1p-Sli15p-Bir1p complex that regulates kinetochore-microtubule attachments, activation of the spindle tension checkpoint, and mitotic spindle disassembly; regulates the activity and localization of the Ipl1p aurora kinase
YGL049C 0.88 Translation initiation factor eIF4G, subunit of the mRNA cap-binding protein complex (eIF4F) that also contains eIF4E (Cdc33p); associates with the poly(A)-binding protein Pab1p, also interacts with eIF4A (Tif1p); homologous to Tif4631p

Network of associatons between targets according to the STRING database.

First level regulatory network of FKH2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.3 16.3 GO:0010696 positive regulation of spindle pole body separation(GO:0010696)
2.0 2.0 GO:0007020 microtubule nucleation(GO:0007020) microtubule polymerization(GO:0046785)
1.5 6.0 GO:0000092 mitotic anaphase B(GO:0000092)
1.0 5.1 GO:0045597 positive regulation of cell fate commitment(GO:0010455) positive regulation of mating type switching(GO:0031496) positive regulation of cell differentiation(GO:0045597)
0.9 4.7 GO:0060277 obsolete negative regulation of transcription involved in G1 phase of mitotic cell cycle(GO:0060277)
0.9 2.7 GO:0009298 GDP-mannose biosynthetic process(GO:0009298) GDP-mannose metabolic process(GO:0019673)
0.7 2.2 GO:0072363 regulation of glycolytic process by regulation of transcription from RNA polymerase II promoter(GO:0072361) regulation of glycolytic process by positive regulation of transcription from RNA polymerase II promoter(GO:0072363)
0.7 5.0 GO:0070058 tRNA gene clustering(GO:0070058)
0.7 2.8 GO:0000461 endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000461)
0.7 1.3 GO:0097271 protein localization to bud neck(GO:0097271)
0.6 1.9 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.6 3.0 GO:0043433 negative regulation of sequence-specific DNA binding transcription factor activity(GO:0043433)
0.6 2.2 GO:0007535 donor selection(GO:0007535)
0.6 2.2 GO:0045719 negative regulation of glycogen biosynthetic process(GO:0045719) negative regulation of glycogen metabolic process(GO:0070874)
0.5 2.1 GO:0034473 U1 snRNA 3'-end processing(GO:0034473)
0.5 1.5 GO:0000098 sulfur amino acid catabolic process(GO:0000098)
0.5 3.9 GO:0000372 Group I intron splicing(GO:0000372) RNA splicing, via transesterification reactions with guanosine as nucleophile(GO:0000376)
0.5 4.4 GO:0031578 mitotic spindle orientation checkpoint(GO:0031578)
0.5 0.9 GO:0051225 spindle assembly(GO:0051225)
0.4 2.2 GO:0045033 peroxisome inheritance(GO:0045033)
0.4 3.4 GO:0034501 protein localization to kinetochore(GO:0034501)
0.4 3.3 GO:0000022 mitotic spindle elongation(GO:0000022) spindle elongation(GO:0051231)
0.4 3.6 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.4 1.6 GO:0046898 response to organic cyclic compound(GO:0014070) response to cycloheximide(GO:0046898)
0.4 7.4 GO:0030472 mitotic spindle organization in nucleus(GO:0030472)
0.4 0.4 GO:0035337 fatty-acyl-CoA metabolic process(GO:0035337)
0.4 5.3 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.4 1.1 GO:0043419 urea catabolic process(GO:0043419)
0.4 1.8 GO:0042710 biofilm formation(GO:0042710)
0.4 1.8 GO:0071406 response to methylmercury(GO:0051597) cellular response to methylmercury(GO:0071406)
0.4 1.4 GO:0070550 rDNA condensation(GO:0070550)
0.4 2.1 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.3 1.4 GO:0007076 mitotic chromosome condensation(GO:0007076)
0.3 1.4 GO:0043007 maintenance of rDNA(GO:0043007)
0.3 1.4 GO:0051457 maintenance of protein location in nucleus(GO:0051457)
0.3 1.0 GO:0019419 sulfate assimilation, phosphoadenylyl sulfate reduction by phosphoadenylyl-sulfate reductase (thioredoxin)(GO:0019379) sulfate reduction(GO:0019419)
0.3 1.0 GO:0051230 mitotic spindle disassembly(GO:0051228) spindle disassembly(GO:0051230)
0.3 1.3 GO:0036213 actomyosin contractile ring contraction(GO:0000916) contractile ring contraction(GO:0036213)
0.3 10.6 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.3 0.3 GO:0010695 regulation of spindle pole body separation(GO:0010695)
0.3 0.6 GO:0009211 pyrimidine deoxyribonucleoside triphosphate metabolic process(GO:0009211)
0.3 1.5 GO:0000433 negative regulation of transcription from RNA polymerase II promoter by glucose(GO:0000433) negative regulation of transcription by glucose(GO:0045014)
0.3 0.9 GO:0006068 ethanol catabolic process(GO:0006068) primary alcohol catabolic process(GO:0034310)
0.3 2.8 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
0.3 0.6 GO:0061412 positive regulation of transcription from RNA polymerase II promoter in response to amino acid starvation(GO:0061412)
0.3 6.0 GO:0006450 regulation of translational fidelity(GO:0006450)
0.3 0.9 GO:2000877 regulation of oligopeptide transport by regulation of transcription from RNA polymerase II promoter(GO:0035950) negative regulation of oligopeptide transport by negative regulation of transcription from RNA polymerase II promoter(GO:0035952) regulation of dipeptide transport by regulation of transcription from RNA polymerase II promoter(GO:0035953) negative regulation of dipeptide transport by negative regulation of transcription from RNA polymerase II promoter(GO:0035955) negative regulation of oligopeptide transport(GO:2000877) negative regulation of dipeptide transport(GO:2000879)
0.3 3.3 GO:0043001 Golgi to plasma membrane protein transport(GO:0043001)
0.3 2.4 GO:0035023 regulation of Rho protein signal transduction(GO:0035023)
0.3 1.8 GO:0001100 negative regulation of exit from mitosis(GO:0001100)
0.3 2.6 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.3 0.9 GO:1904668 positive regulation of mitotic nuclear division(GO:0045840) positive regulation of mitotic metaphase/anaphase transition(GO:0045842) positive regulation of mitotic sister chromatid separation(GO:1901970) positive regulation of metaphase/anaphase transition of cell cycle(GO:1902101) positive regulation of ubiquitin protein ligase activity(GO:1904668)
0.3 1.1 GO:0031507 heterochromatin assembly(GO:0031507)
0.3 1.1 GO:0031565 obsolete cytokinesis checkpoint(GO:0031565)
0.3 1.7 GO:0048478 replication fork protection(GO:0048478)
0.3 0.6 GO:0007189 adenylate cyclase-activating G-protein coupled receptor signaling pathway(GO:0007189)
0.3 1.9 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
0.3 1.1 GO:0031591 wybutosine metabolic process(GO:0031590) wybutosine biosynthetic process(GO:0031591)
0.3 1.6 GO:0031382 mating projection assembly(GO:0031382)
0.3 1.3 GO:0045947 negative regulation of translational initiation(GO:0045947)
0.3 0.3 GO:0034502 protein localization to chromosome(GO:0034502)
0.3 32.6 GO:0002181 cytoplasmic translation(GO:0002181)
0.3 6.6 GO:0006334 nucleosome assembly(GO:0006334)
0.3 1.3 GO:0032012 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.3 3.4 GO:0030473 establishment of localization by movement along microtubule(GO:0010970) nuclear migration along microtubule(GO:0030473) organelle transport along microtubule(GO:0072384)
0.3 0.8 GO:1902750 negative regulation of G2/M transition of mitotic cell cycle(GO:0010972) mitotic G2/M transition checkpoint(GO:0044818) negative regulation of cell cycle G2/M phase transition(GO:1902750)
0.3 2.3 GO:0000921 septin ring assembly(GO:0000921)
0.3 1.0 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.2 0.5 GO:0008054 negative regulation of cyclin-dependent protein serine/threonine kinase by cyclin degradation(GO:0008054) negative regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045736) negative regulation of cyclin-dependent protein kinase activity(GO:1904030)
0.2 0.5 GO:0006407 rRNA export from nucleus(GO:0006407) rRNA transport(GO:0051029)
0.2 0.2 GO:0033500 cellular glucose homeostasis(GO:0001678) carbohydrate mediated signaling(GO:0009756) hexose mediated signaling(GO:0009757) sugar mediated signaling pathway(GO:0010182) glucose mediated signaling pathway(GO:0010255) carbohydrate homeostasis(GO:0033500) glucose homeostasis(GO:0042593) cellular response to monosaccharide stimulus(GO:0071326) cellular response to hexose stimulus(GO:0071331) cellular response to glucose stimulus(GO:0071333)
0.2 0.2 GO:0090329 regulation of DNA-dependent DNA replication(GO:0090329)
0.2 0.7 GO:0017157 regulation of exocytosis(GO:0017157) regulation of secretion(GO:0051046) regulation of secretion by cell(GO:1903530)
0.2 1.2 GO:0036228 protein targeting to nuclear inner membrane(GO:0036228)
0.2 1.4 GO:0045860 positive regulation of protein kinase activity(GO:0045860)
0.2 0.2 GO:0048211 Golgi vesicle docking(GO:0048211)
0.2 0.5 GO:0016049 cell growth(GO:0016049)
0.2 0.9 GO:0032211 negative regulation of telomere maintenance via telomerase(GO:0032211) negative regulation of telomere maintenance via telomere lengthening(GO:1904357)
0.2 0.9 GO:0060963 positive regulation of ribosomal protein gene transcription from RNA polymerase II promoter(GO:0060963)
0.2 0.4 GO:1900544 positive regulation of nucleotide metabolic process(GO:0045981) positive regulation of purine nucleotide metabolic process(GO:1900544)
0.2 2.1 GO:0032392 DNA geometric change(GO:0032392)
0.2 1.0 GO:0000706 meiotic DNA double-strand break processing(GO:0000706) DNA double-strand break processing(GO:0000729)
0.2 0.4 GO:0015909 long-chain fatty acid transport(GO:0015909)
0.2 0.6 GO:0006741 NADP biosynthetic process(GO:0006741)
0.2 0.4 GO:0009847 spore germination(GO:0009847)
0.2 0.4 GO:0007052 mitotic spindle organization(GO:0007052)
0.2 0.2 GO:0061422 positive regulation of transcription from RNA polymerase II promoter in response to alkaline pH(GO:0061422)
0.2 0.5 GO:0009162 deoxyribonucleoside monophosphate biosynthetic process(GO:0009157) deoxyribonucleoside monophosphate metabolic process(GO:0009162) pyrimidine deoxyribonucleoside monophosphate metabolic process(GO:0009176) pyrimidine deoxyribonucleoside monophosphate biosynthetic process(GO:0009177)
0.2 0.5 GO:0000087 mitotic M phase(GO:0000087) M phase(GO:0000279)
0.2 0.7 GO:0070072 proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.2 0.4 GO:0051865 protein autoubiquitination(GO:0051865)
0.2 9.3 GO:0007124 pseudohyphal growth(GO:0007124)
0.2 0.7 GO:0006333 chromatin assembly or disassembly(GO:0006333)
0.2 0.5 GO:0007232 osmosensory signaling pathway via Sho1 osmosensor(GO:0007232)
0.2 0.9 GO:0001676 long-chain fatty acid metabolic process(GO:0001676)
0.2 0.9 GO:0006363 termination of RNA polymerase I transcription(GO:0006363)
0.2 0.7 GO:0000715 nucleotide-excision repair, DNA damage recognition(GO:0000715)
0.2 3.6 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.2 0.3 GO:0008334 histone mRNA metabolic process(GO:0008334) histone mRNA catabolic process(GO:0071044)
0.2 1.3 GO:0007533 mating type switching(GO:0007533)
0.2 0.5 GO:0051647 nuclear migration(GO:0007097) establishment of nucleus localization(GO:0040023) nucleus localization(GO:0051647)
0.2 0.6 GO:0006285 base-excision repair, AP site formation(GO:0006285)
0.2 1.0 GO:0006617 SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition(GO:0006617)
0.2 0.8 GO:0072668 obsolete tubulin complex biogenesis(GO:0072668)
0.2 0.2 GO:0090435 protein localization to nuclear envelope(GO:0090435)
0.1 0.3 GO:0033262 regulation of nuclear cell cycle DNA replication(GO:0033262)
0.1 1.5 GO:1902299 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
0.1 3.0 GO:0006378 mRNA polyadenylation(GO:0006378)
0.1 0.6 GO:0006279 premeiotic DNA replication(GO:0006279)
0.1 1.5 GO:0090529 barrier septum assembly(GO:0000917) cell septum assembly(GO:0090529)
0.1 0.7 GO:0016233 telomere capping(GO:0016233)
0.1 2.2 GO:0030488 tRNA methylation(GO:0030488)
0.1 1.1 GO:0045943 positive regulation of transcription from RNA polymerase I promoter(GO:0045943)
0.1 0.4 GO:0006362 transcription elongation from RNA polymerase I promoter(GO:0006362)
0.1 0.7 GO:0016479 negative regulation of transcription from RNA polymerase I promoter(GO:0016479)
0.1 0.3 GO:0009186 deoxyribonucleoside diphosphate metabolic process(GO:0009186)
0.1 0.7 GO:0035434 copper ion transmembrane transport(GO:0035434)
0.1 0.7 GO:0006491 N-glycan processing(GO:0006491)
0.1 0.5 GO:0015867 ATP transport(GO:0015867)
0.1 1.3 GO:0007096 regulation of exit from mitosis(GO:0007096)
0.1 0.4 GO:0006571 tyrosine biosynthetic process(GO:0006571)
0.1 0.3 GO:0001109 promoter clearance during DNA-templated transcription(GO:0001109) promoter clearance from RNA polymerase II promoter(GO:0001111)
0.1 0.6 GO:0042255 ribosome assembly(GO:0042255)
0.1 0.5 GO:0000296 spermine transport(GO:0000296)
0.1 2.0 GO:0006283 transcription-coupled nucleotide-excision repair(GO:0006283)
0.1 0.5 GO:0009423 chorismate biosynthetic process(GO:0009423) chorismate metabolic process(GO:0046417)
0.1 0.2 GO:0010922 positive regulation of phosphatase activity(GO:0010922)
0.1 0.5 GO:0033683 nucleotide-excision repair, DNA incision(GO:0033683)
0.1 0.9 GO:0000321 re-entry into mitotic cell cycle after pheromone arrest(GO:0000321)
0.1 0.6 GO:0071039 nuclear polyadenylation-dependent CUT catabolic process(GO:0071039)
0.1 0.5 GO:0015809 arginine transport(GO:0015809)
0.1 1.0 GO:0007118 budding cell apical bud growth(GO:0007118)
0.1 0.9 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.1 0.5 GO:0031118 rRNA pseudouridine synthesis(GO:0031118)
0.1 0.6 GO:0034284 response to hexose(GO:0009746) response to glucose(GO:0009749) response to monosaccharide(GO:0034284)
0.1 0.1 GO:0007018 microtubule-based movement(GO:0007018)
0.1 0.3 GO:0015740 C4-dicarboxylate transport(GO:0015740)
0.1 0.5 GO:0001927 exocyst assembly(GO:0001927)
0.1 0.3 GO:0046039 GTP biosynthetic process(GO:0006183) GTP metabolic process(GO:0046039)
0.1 0.4 GO:0019344 cysteine biosynthetic process(GO:0019344)
0.1 0.6 GO:0032042 mitochondrial DNA metabolic process(GO:0032042)
0.1 0.2 GO:1901073 aminoglycan biosynthetic process(GO:0006023) chitin biosynthetic process(GO:0006031) glucosamine-containing compound biosynthetic process(GO:1901073)
0.1 1.9 GO:0042147 retrograde transport, endosome to Golgi(GO:0042147)
0.1 0.4 GO:0030261 chromosome condensation(GO:0030261)
0.1 0.6 GO:0051598 meiotic cell cycle checkpoint(GO:0033313) meiotic recombination checkpoint(GO:0051598)
0.1 0.2 GO:0034402 recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex(GO:0034402)
0.1 0.4 GO:0090522 vesicle tethering involved in exocytosis(GO:0090522)
0.1 0.6 GO:0070124 mitochondrial translational initiation(GO:0070124)
0.1 0.4 GO:0070588 calcium ion transmembrane transport(GO:0070588)
0.1 0.2 GO:0000078 obsolete cytokinesis after mitosis checkpoint(GO:0000078) positive regulation of G2/M transition of mitotic cell cycle(GO:0010971) positive regulation of cell cycle G2/M phase transition(GO:1902751)
0.1 1.4 GO:0031498 nucleosome disassembly(GO:0006337) chromatin disassembly(GO:0031498) protein-DNA complex disassembly(GO:0032986)
0.1 0.6 GO:0009306 protein secretion(GO:0009306)
0.1 2.5 GO:0000480 endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000480)
0.1 0.1 GO:0072417 cellular response to biotic stimulus(GO:0071216) response to cell cycle checkpoint signaling(GO:0072396) response to mitotic cell cycle checkpoint signaling(GO:0072414) response to spindle checkpoint signaling(GO:0072417) response to mitotic spindle checkpoint signaling(GO:0072476) response to mitotic cell cycle spindle assembly checkpoint signaling(GO:0072479) response to spindle assembly checkpoint signaling(GO:0072485) negative regulation of protein import into nucleus during spindle assembly checkpoint(GO:1901925)
0.1 1.4 GO:0042797 tRNA transcription(GO:0009304) tRNA transcription from RNA polymerase III promoter(GO:0042797)
0.1 1.4 GO:0031577 spindle checkpoint(GO:0031577)
0.1 0.5 GO:0034063 stress granule assembly(GO:0034063)
0.1 0.7 GO:0007120 axial cellular bud site selection(GO:0007120)
0.1 0.2 GO:0042538 hyperosmotic salinity response(GO:0042538)
0.1 3.2 GO:0000725 recombinational repair(GO:0000725)
0.1 0.3 GO:0031335 regulation of sulfur amino acid metabolic process(GO:0031335)
0.1 1.2 GO:0000077 DNA damage checkpoint(GO:0000077)
0.1 0.6 GO:0034067 protein localization to Golgi apparatus(GO:0034067)
0.1 0.1 GO:0016093 polyprenol metabolic process(GO:0016093) polyprenol biosynthetic process(GO:0016094) dolichol metabolic process(GO:0019348) dolichol biosynthetic process(GO:0019408)
0.1 2.6 GO:0043547 positive regulation of GTPase activity(GO:0043547)
0.1 0.2 GO:0071454 response to anoxia(GO:0034059) cellular response to anoxia(GO:0071454)
0.1 0.7 GO:0000741 karyogamy(GO:0000741) karyogamy involved in conjugation with cellular fusion(GO:0000742)
0.1 1.0 GO:0000011 vacuole inheritance(GO:0000011)
0.1 0.8 GO:0016925 protein sumoylation(GO:0016925)
0.1 0.5 GO:0070941 eisosome assembly(GO:0070941)
0.1 0.6 GO:0036003 positive regulation of transcription from RNA polymerase II promoter in response to stress(GO:0036003)
0.1 0.3 GO:0000949 aromatic amino acid family catabolic process to alcohol via Ehrlich pathway(GO:0000949)
0.1 1.0 GO:0030474 spindle pole body duplication(GO:0030474)
0.1 0.4 GO:0045116 protein neddylation(GO:0045116)
0.1 0.6 GO:0043457 regulation of cellular respiration(GO:0043457)
0.1 0.4 GO:0007021 tubulin complex assembly(GO:0007021)
0.1 0.2 GO:2000058 regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:2000058)
0.1 3.6 GO:0042274 ribosomal small subunit biogenesis(GO:0042274)
0.1 0.2 GO:1901985 regulation of histone acetylation(GO:0035065) positive regulation of histone acetylation(GO:0035066) regulation of protein acetylation(GO:1901983) positive regulation of protein acetylation(GO:1901985) regulation of peptidyl-lysine acetylation(GO:2000756) positive regulation of peptidyl-lysine acetylation(GO:2000758)
0.1 0.3 GO:0015883 FAD transport(GO:0015883)
0.1 0.8 GO:0006379 mRNA cleavage(GO:0006379)
0.1 0.2 GO:0061393 positive regulation of transcription from RNA polymerase II promoter in response to osmotic stress(GO:0061393)
0.1 0.5 GO:0033962 cytoplasmic mRNA processing body assembly(GO:0033962)
0.1 0.9 GO:0006353 DNA-templated transcription, termination(GO:0006353)
0.1 0.5 GO:0060304 regulation of phosphatidylinositol dephosphorylation(GO:0060304) endoplasmic reticulum membrane organization(GO:0090158)
0.1 0.2 GO:0051668 localization within membrane(GO:0051668)
0.1 1.7 GO:0006896 Golgi to vacuole transport(GO:0006896)
0.1 0.6 GO:1903338 regulation of cell wall organization or biogenesis(GO:1903338)
0.1 0.5 GO:0016559 peroxisome fission(GO:0016559)
0.1 0.2 GO:0008612 peptidyl-lysine modification to peptidyl-hypusine(GO:0008612)
0.1 0.2 GO:0034517 ribophagy(GO:0034517)
0.1 1.0 GO:0031929 TOR signaling(GO:0031929)
0.1 0.2 GO:0006390 transcription from mitochondrial promoter(GO:0006390)
0.1 0.2 GO:0001308 negative regulation of chromatin silencing involved in replicative cell aging(GO:0001308)
0.1 0.1 GO:0010513 positive regulation of phosphatidylinositol biosynthetic process(GO:0010513)
0.1 1.3 GO:0006885 regulation of pH(GO:0006885)
0.1 0.1 GO:0046823 negative regulation of intracellular transport(GO:0032387) negative regulation of protein import into nucleus(GO:0042308) negative regulation of nucleocytoplasmic transport(GO:0046823) negative regulation of protein transport(GO:0051224) negative regulation of intracellular protein transport(GO:0090317) negative regulation of protein localization to nucleus(GO:1900181) negative regulation of cytoplasmic transport(GO:1903650) negative regulation of cellular protein localization(GO:1903828) negative regulation of protein import(GO:1904590) negative regulation of establishment of protein localization(GO:1904950)
0.1 0.6 GO:0070525 tRNA threonylcarbamoyladenosine metabolic process(GO:0070525)
0.1 0.5 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.1 0.3 GO:0002943 tRNA dihydrouridine synthesis(GO:0002943)
0.1 0.1 GO:0006658 phosphatidylserine metabolic process(GO:0006658)
0.1 0.4 GO:0006446 regulation of translational initiation(GO:0006446)
0.1 0.5 GO:0009113 purine nucleobase biosynthetic process(GO:0009113)
0.1 1.4 GO:0030466 chromatin silencing at silent mating-type cassette(GO:0030466)
0.1 0.4 GO:0009395 phospholipid catabolic process(GO:0009395)
0.1 0.8 GO:0010383 cell wall chitin metabolic process(GO:0006037) cell wall polysaccharide metabolic process(GO:0010383)
0.1 0.2 GO:0030835 regulation of actin filament depolymerization(GO:0030834) negative regulation of actin filament depolymerization(GO:0030835) barbed-end actin filament capping(GO:0051016) actin filament capping(GO:0051693)
0.1 0.2 GO:0031120 snRNA pseudouridine synthesis(GO:0031120) snRNA modification(GO:0040031)
0.1 0.2 GO:0048279 vesicle fusion with endoplasmic reticulum(GO:0048279)
0.1 0.2 GO:0042938 dipeptide transport(GO:0042938)
0.1 0.4 GO:0048278 vesicle docking(GO:0048278)
0.1 0.1 GO:0071168 protein localization to chromatin(GO:0071168)
0.1 0.5 GO:0015833 peptide transport(GO:0015833)
0.1 0.1 GO:0071049 nuclear mRNA surveillance of mRNA 3'-end processing(GO:0071031) nuclear retention of pre-mRNA with aberrant 3'-ends at the site of transcription(GO:0071049)
0.1 0.2 GO:0030497 fatty acid elongation(GO:0030497)
0.1 0.1 GO:0000733 DNA strand renaturation(GO:0000733)
0.1 0.1 GO:0070933 histone H3 deacetylation(GO:0070932) histone H4 deacetylation(GO:0070933)
0.1 0.1 GO:0007234 osmosensory signaling via phosphorelay pathway(GO:0007234)
0.1 0.4 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.1 0.3 GO:0071046 polyadenylation-dependent ncRNA catabolic process(GO:0043634) nuclear ncRNA surveillance(GO:0071029) nuclear polyadenylation-dependent ncRNA catabolic process(GO:0071046)
0.1 1.4 GO:0044108 ergosterol biosynthetic process(GO:0006696) phytosteroid biosynthetic process(GO:0016129) cellular alcohol biosynthetic process(GO:0044108) cellular lipid biosynthetic process(GO:0097384)
0.1 0.2 GO:0006359 regulation of transcription from RNA polymerase III promoter(GO:0006359)
0.0 0.2 GO:0046500 S-adenosylmethionine metabolic process(GO:0046500)
0.0 0.3 GO:0010388 protein deneddylation(GO:0000338) cullin deneddylation(GO:0010388)
0.0 0.1 GO:0042868 antisense RNA transcription(GO:0009300) antisense RNA metabolic process(GO:0042868) regulation of antisense RNA transcription(GO:0060194) negative regulation of antisense RNA transcription(GO:0060195)
0.0 0.1 GO:0016320 endoplasmic reticulum membrane fusion(GO:0016320)
0.0 0.4 GO:0006067 ethanol metabolic process(GO:0006067)
0.0 0.1 GO:0051382 centromere complex assembly(GO:0034508) kinetochore assembly(GO:0051382) kinetochore organization(GO:0051383)
0.0 0.9 GO:0006413 translational initiation(GO:0006413)
0.0 3.6 GO:0051169 nucleocytoplasmic transport(GO:0006913) nuclear transport(GO:0051169)
0.0 1.3 GO:0010564 regulation of cell cycle process(GO:0010564)
0.0 0.7 GO:0006730 one-carbon metabolic process(GO:0006730)
0.0 0.2 GO:0071804 cellular potassium ion transport(GO:0071804) potassium ion transmembrane transport(GO:0071805)
0.0 0.3 GO:0000753 cell morphogenesis involved in conjugation with cellular fusion(GO:0000753)
0.0 0.2 GO:0051131 chaperone-mediated protein complex assembly(GO:0051131)
0.0 0.2 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.0 0.1 GO:0018206 N-terminal peptidyl-methionine acetylation(GO:0017196) peptidyl-methionine modification(GO:0018206)
0.0 0.3 GO:0009410 response to xenobiotic stimulus(GO:0009410)
0.0 0.1 GO:0046087 cytidine metabolic process(GO:0046087)
0.0 0.2 GO:0044848 biological phase(GO:0044848)
0.0 0.0 GO:1900088 regulation of carbohydrate metabolic process by transcription from RNA polymerase II promoter(GO:0100024) regulation of inositol biosynthetic process(GO:1900088) positive regulation of inositol biosynthetic process(GO:1900090) regulation of carbohydrate metabolic process by regulation of transcription from RNA polymerase II promoter(GO:1900402)
0.0 0.1 GO:0044038 cell wall macromolecule biosynthetic process(GO:0044038) cellular component macromolecule biosynthetic process(GO:0070589)
0.0 0.5 GO:0042790 transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:0042790)
0.0 0.1 GO:0019358 nicotinate nucleotide biosynthetic process(GO:0019357) nicotinate nucleotide salvage(GO:0019358) pyridine nucleotide salvage(GO:0019365) nicotinate nucleotide metabolic process(GO:0046497)
0.0 0.1 GO:0010969 regulation of pheromone-dependent signal transduction involved in conjugation with cellular fusion(GO:0010969) regulation of signal transduction involved in conjugation with cellular fusion(GO:0060238)
0.0 0.2 GO:0009396 folic acid-containing compound metabolic process(GO:0006760) folic acid-containing compound biosynthetic process(GO:0009396) pteridine-containing compound metabolic process(GO:0042558) pteridine-containing compound biosynthetic process(GO:0042559)
0.0 0.2 GO:0009312 trehalose biosynthetic process(GO:0005992) oligosaccharide biosynthetic process(GO:0009312) disaccharide biosynthetic process(GO:0046351)
0.0 0.1 GO:0046160 heme a biosynthetic process(GO:0006784) heme a metabolic process(GO:0046160)
0.0 0.1 GO:0000957 mitochondrial RNA catabolic process(GO:0000957)
0.0 0.1 GO:0000390 spliceosomal complex disassembly(GO:0000390)
0.0 0.3 GO:0000350 generation of catalytic spliceosome for second transesterification step(GO:0000350)
0.0 0.2 GO:0072595 maintenance of protein localization in organelle(GO:0072595)
0.0 3.5 GO:0000280 nuclear division(GO:0000280)
0.0 0.1 GO:0070988 protein demethylation(GO:0006482) protein dealkylation(GO:0008214) histone demethylation(GO:0016577) demethylation(GO:0070988)
0.0 0.9 GO:0006487 protein N-linked glycosylation(GO:0006487)
0.0 0.1 GO:0046341 CDP-diacylglycerol biosynthetic process(GO:0016024) CDP-diacylglycerol metabolic process(GO:0046341)
0.0 0.1 GO:1901658 nucleoside catabolic process(GO:0009164) glycosyl compound catabolic process(GO:1901658)
0.0 0.1 GO:0009051 pentose-phosphate shunt, oxidative branch(GO:0009051)
0.0 0.1 GO:0032581 ER-dependent peroxisome organization(GO:0032581)
0.0 0.0 GO:0007030 Golgi organization(GO:0007030)
0.0 0.1 GO:0046349 amino sugar biosynthetic process(GO:0046349)
0.0 0.8 GO:0006879 cellular iron ion homeostasis(GO:0006879)
0.0 0.1 GO:0018344 protein geranylgeranylation(GO:0018344)
0.0 0.1 GO:0051083 'de novo' cotranslational protein folding(GO:0051083)
0.0 0.2 GO:0006474 N-terminal protein amino acid acetylation(GO:0006474)
0.0 0.2 GO:0055069 cellular zinc ion homeostasis(GO:0006882) zinc ion homeostasis(GO:0055069)
0.0 0.0 GO:0002376 immune effector process(GO:0002252) immune system process(GO:0002376) defense response(GO:0006952) response to virus(GO:0009615) response to external biotic stimulus(GO:0043207) defense response to virus(GO:0051607) response to other organism(GO:0051707) defense response to other organism(GO:0098542)
0.0 0.1 GO:0006021 inositol biosynthetic process(GO:0006021)
0.0 0.1 GO:0042780 tRNA 3'-end processing(GO:0042780)
0.0 0.3 GO:0048311 mitochondrion inheritance(GO:0000001) mitochondrion distribution(GO:0048311)
0.0 0.0 GO:0070676 intralumenal vesicle formation(GO:0070676)
0.0 0.1 GO:0034249 negative regulation of cellular amide metabolic process(GO:0034249)
0.0 0.1 GO:0034661 ncRNA catabolic process(GO:0034661)
0.0 0.1 GO:0023021 termination of signal transduction(GO:0023021) termination of G-protein coupled receptor signaling pathway(GO:0038032)
0.0 0.1 GO:0009268 response to pH(GO:0009268)
0.0 0.1 GO:0006448 regulation of translational elongation(GO:0006448)
0.0 0.3 GO:0006513 protein monoubiquitination(GO:0006513)
0.0 0.2 GO:0044396 actin cortical patch assembly(GO:0000147) actin cortical patch organization(GO:0044396)
0.0 0.1 GO:0055088 lipid homeostasis(GO:0055088)
0.0 0.4 GO:0042144 vacuole fusion, non-autophagic(GO:0042144)
0.0 0.1 GO:0045292 mRNA cis splicing, via spliceosome(GO:0045292)
0.0 0.3 GO:0016579 protein deubiquitination(GO:0016579)
0.0 0.1 GO:0046416 D-amino acid metabolic process(GO:0046416)
0.0 0.0 GO:0090295 nitrogen catabolite repression of transcription(GO:0090295)
0.0 0.1 GO:0000388 spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)(GO:0000388)
0.0 0.2 GO:0007039 protein catabolic process in the vacuole(GO:0007039)
0.0 0.2 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.0 0.1 GO:0046685 response to arsenic-containing substance(GO:0046685)
0.0 0.2 GO:0006515 misfolded or incompletely synthesized protein catabolic process(GO:0006515)
0.0 0.2 GO:0045727 positive regulation of cellular amide metabolic process(GO:0034250) positive regulation of translation(GO:0045727)
0.0 0.5 GO:0006888 ER to Golgi vesicle-mediated transport(GO:0006888)
0.0 0.2 GO:0018022 peptidyl-lysine methylation(GO:0018022)
0.0 0.2 GO:0034620 endoplasmic reticulum unfolded protein response(GO:0030968) cellular response to unfolded protein(GO:0034620)
0.0 0.1 GO:0046219 tryptophan biosynthetic process(GO:0000162) indole-containing compound biosynthetic process(GO:0042435) indolalkylamine biosynthetic process(GO:0046219)
0.0 0.1 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0 0.1 GO:0006906 vesicle fusion(GO:0006906) organelle membrane fusion(GO:0090174)
0.0 0.1 GO:0006273 lagging strand elongation(GO:0006273)
0.0 0.1 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0 0.1 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.0 0.1 GO:0006303 double-strand break repair via nonhomologous end joining(GO:0006303)
0.0 0.2 GO:0016197 endosomal transport(GO:0016197)
0.0 0.1 GO:0051666 actin cortical patch localization(GO:0051666)
0.0 0.0 GO:0006655 phosphatidylglycerol biosynthetic process(GO:0006655)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 7.4 GO:0005871 kinesin complex(GO:0005871)
0.9 2.8 GO:0008275 gamma-tubulin small complex, spindle pole body(GO:0000928) gamma-tubulin complex(GO:0000930) gamma-tubulin small complex(GO:0008275)
0.8 5.0 GO:0000796 condensin complex(GO:0000796) nuclear condensin complex(GO:0000799)
0.7 0.7 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.7 5.7 GO:0051233 spindle midzone(GO:0051233)
0.7 2.8 GO:0034990 mitotic cohesin complex(GO:0030892) nuclear mitotic cohesin complex(GO:0034990)
0.7 6.1 GO:0000144 cellular bud neck septin ring(GO:0000144)
0.6 2.5 GO:0000444 MIS12/MIND type complex(GO:0000444) nuclear MIS12/MIND complex(GO:0000818)
0.5 0.5 GO:0005822 inner plaque of spindle pole body(GO:0005822)
0.5 3.8 GO:0042597 periplasmic space(GO:0042597)
0.5 2.7 GO:0042555 MCM complex(GO:0042555)
0.5 5.5 GO:0000788 nuclear nucleosome(GO:0000788)
0.5 5.4 GO:0000142 cellular bud neck contractile ring(GO:0000142)
0.4 3.5 GO:0005724 nuclear heterochromatin(GO:0005720) nuclear telomeric heterochromatin(GO:0005724) telomeric heterochromatin(GO:0031933)
0.4 2.6 GO:0005884 actin filament(GO:0005884)
0.4 1.7 GO:0033597 mitotic checkpoint complex(GO:0033597)
0.4 34.2 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.4 1.6 GO:0030907 MBF transcription complex(GO:0030907)
0.4 1.2 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.4 1.5 GO:0000817 COMA complex(GO:0000817)
0.4 21.7 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.3 1.7 GO:0032545 CURI complex(GO:0032545)
0.3 0.3 GO:0005826 actomyosin contractile ring(GO:0005826) contractile ring(GO:0070938)
0.3 0.3 GO:0005869 dynactin complex(GO:0005869)
0.3 1.7 GO:0033100 NuA3 histone acetyltransferase complex(GO:0033100) H3 histone acetyltransferase complex(GO:0070775)
0.3 5.3 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.3 25.6 GO:0005819 spindle(GO:0005819)
0.3 2.4 GO:0017119 Golgi transport complex(GO:0017119)
0.3 2.7 GO:0000137 Golgi cis cisterna(GO:0000137)
0.3 1.2 GO:0000938 GARP complex(GO:0000938)
0.3 1.7 GO:0043527 tRNA methyltransferase complex(GO:0043527)
0.3 1.1 GO:0097196 Shu complex(GO:0097196)
0.3 2.9 GO:0016514 SWI/SNF complex(GO:0016514) BAF-type complex(GO:0090544)
0.3 1.8 GO:0044615 nuclear pore nuclear basket(GO:0044615)
0.3 1.0 GO:0031262 Ndc80 complex(GO:0031262)
0.3 0.5 GO:0000229 cytoplasmic chromosome(GO:0000229) mitochondrial chromosome(GO:0000262)
0.2 1.0 GO:0017053 transcriptional repressor complex(GO:0017053)
0.2 1.2 GO:0005771 multivesicular body(GO:0005771)
0.2 0.7 GO:0051286 cell tip(GO:0051286)
0.2 4.1 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.2 3.1 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)
0.2 0.7 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.2 0.7 GO:0070274 RES complex(GO:0070274)
0.2 1.1 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.2 1.4 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.2 0.7 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.2 0.8 GO:0030123 AP-3 adaptor complex(GO:0030123)
0.2 0.8 GO:0031315 extrinsic component of mitochondrial outer membrane(GO:0031315)
0.2 1.0 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)
0.2 1.0 GO:0005641 nuclear envelope lumen(GO:0005641)
0.2 1.3 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.2 0.9 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.2 0.6 GO:0033551 monopolin complex(GO:0033551)
0.2 0.5 GO:0070390 transcription export complex 2(GO:0070390)
0.2 0.5 GO:0070545 PeBoW complex(GO:0070545)
0.2 0.5 GO:0033186 CAF-1 complex(GO:0033186)
0.2 0.7 GO:0005640 nuclear outer membrane(GO:0005640)
0.2 1.8 GO:0005637 nuclear inner membrane(GO:0005637)
0.2 1.0 GO:0000783 telomere cap complex(GO:0000782) nuclear telomere cap complex(GO:0000783)
0.2 1.1 GO:0034455 t-UTP complex(GO:0034455)
0.2 1.0 GO:0048500 signal recognition particle, endoplasmic reticulum targeting(GO:0005786) signal recognition particle(GO:0048500)
0.2 0.6 GO:0005946 alpha,alpha-trehalose-phosphate synthase complex (UDP-forming)(GO:0005946)
0.2 0.3 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.2 0.8 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.1 1.3 GO:0031261 DNA replication preinitiation complex(GO:0031261)
0.1 1.0 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.1 1.7 GO:0000778 condensed nuclear chromosome kinetochore(GO:0000778)
0.1 0.3 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.1 0.1 GO:0031105 septin complex(GO:0031105)
0.1 0.3 GO:0016363 nuclear matrix(GO:0016363)
0.1 0.4 GO:0070985 TFIIK complex(GO:0070985)
0.1 5.8 GO:0000131 incipient cellular bud site(GO:0000131)
0.1 0.4 GO:0000417 HIR complex(GO:0000417)
0.1 0.5 GO:0033254 vacuolar transporter chaperone complex(GO:0033254)
0.1 0.2 GO:0000145 exocyst(GO:0000145)
0.1 0.4 GO:0097344 Rix1 complex(GO:0097344)
0.1 0.6 GO:0030689 Noc complex(GO:0030689)
0.1 0.3 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.1 0.5 GO:0031429 box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588)
0.1 0.7 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.1 1.5 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.1 4.5 GO:0030686 90S preribosome(GO:0030686)
0.1 0.1 GO:0000112 nucleotide-excision repair factor 3 complex(GO:0000112)
0.1 1.0 GO:0032806 carboxy-terminal domain protein kinase complex(GO:0032806)
0.1 0.4 GO:0016587 Isw1 complex(GO:0016587)
0.1 7.1 GO:0005935 cellular bud neck(GO:0005935)
0.1 0.6 GO:0032040 small-subunit processome(GO:0032040)
0.1 0.7 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.1 0.5 GO:0032221 Rpd3S complex(GO:0032221)
0.1 0.7 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.1 1.3 GO:0016586 RSC complex(GO:0016586)
0.1 0.3 GO:0000113 nucleotide-excision repair factor 4 complex(GO:0000113)
0.1 0.6 GO:0016272 prefoldin complex(GO:0016272)
0.1 1.0 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.1 0.8 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.1 1.2 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.1 0.7 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.1 0.1 GO:0000133 polarisome(GO:0000133)
0.1 0.2 GO:0030896 checkpoint clamp complex(GO:0030896)
0.1 0.4 GO:0030119 AP-type membrane coat adaptor complex(GO:0030119)
0.1 0.5 GO:0030008 TRAPP complex(GO:0030008)
0.1 0.3 GO:0000500 RNA polymerase I upstream activating factor complex(GO:0000500)
0.1 0.6 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.1 3.8 GO:0005667 transcription factor complex(GO:0005667)
0.1 0.8 GO:0000812 Swr1 complex(GO:0000812)
0.1 0.6 GO:0000784 nuclear chromosome, telomeric region(GO:0000784)
0.1 0.2 GO:0070939 Dsl1p complex(GO:0070939)
0.1 0.3 GO:0031499 TRAMP complex(GO:0031499)
0.1 0.3 GO:0032126 eisosome(GO:0032126)
0.1 0.2 GO:0000815 ESCRT III complex(GO:0000815)
0.1 0.1 GO:0033553 rDNA heterochromatin(GO:0033553)
0.1 0.2 GO:0033101 cellular bud membrane(GO:0033101)
0.1 0.4 GO:0000346 transcription export complex(GO:0000346)
0.1 0.9 GO:0030659 vesicle membrane(GO:0012506) cytoplasmic vesicle membrane(GO:0030659)
0.1 0.7 GO:0031231 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.1 1.4 GO:0005844 polysome(GO:0005844)
0.0 0.3 GO:0008180 COP9 signalosome(GO:0008180)
0.0 0.7 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.0 0.3 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 0.1 GO:0034274 Atg12-Atg5-Atg16 complex(GO:0034274)
0.0 0.2 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.0 0.4 GO:0030915 Smc5-Smc6 complex(GO:0030915)
0.0 0.3 GO:0030897 HOPS complex(GO:0030897)
0.0 0.5 GO:0005686 U2 snRNP(GO:0005686)
0.0 0.1 GO:0071819 DUBm complex(GO:0071819)
0.0 0.1 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.0 1.5 GO:0030134 ER to Golgi transport vesicle(GO:0030134)
0.0 0.1 GO:0030677 ribonuclease P complex(GO:0030677)
0.0 0.2 GO:0035339 serine C-palmitoyltransferase complex(GO:0017059) SPOTS complex(GO:0035339)
0.0 0.1 GO:0030874 nucleolar chromatin(GO:0030874)
0.0 0.2 GO:0031985 Golgi cisterna(GO:0031985)
0.0 0.1 GO:0034399 nuclear periphery(GO:0034399)
0.0 0.1 GO:0031010 ISWI-type complex(GO:0031010)
0.0 0.1 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.0 0.4 GO:0042575 DNA polymerase complex(GO:0042575)
0.0 0.3 GO:0031414 N-terminal protein acetyltransferase complex(GO:0031414)
0.0 0.2 GO:0071008 U2-type post-mRNA release spliceosomal complex(GO:0071008)
0.0 0.6 GO:0031201 SNARE complex(GO:0031201)
0.0 0.1 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.0 0.2 GO:0033180 vacuolar proton-transporting V-type ATPase, V1 domain(GO:0000221) proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0 0.1 GO:0032807 DNA ligase IV complex(GO:0032807)
0.0 0.2 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0 0.1 GO:0005854 nascent polypeptide-associated complex(GO:0005854)
0.0 1.8 GO:0005635 nuclear envelope(GO:0005635)
0.0 2.5 GO:0005730 nucleolus(GO:0005730)
0.0 0.1 GO:0031389 Rad17 RFC-like complex(GO:0031389)
0.0 0.0 GO:0055087 Ski complex(GO:0055087)
0.0 0.1 GO:0034044 exomer complex(GO:0034044)
0.0 0.0 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.0 0.1 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.0 0.0 GO:0000776 kinetochore(GO:0000776)
0.0 0.0 GO:0030870 Mre11 complex(GO:0030870)
0.0 0.2 GO:0036464 ribonucleoprotein granule(GO:0035770) cytoplasmic ribonucleoprotein granule(GO:0036464)
0.0 0.0 GO:0030133 transport vesicle(GO:0030133)
0.0 0.0 GO:0016471 vacuolar proton-transporting V-type ATPase complex(GO:0016471) proton-transporting V-type ATPase complex(GO:0033176)
0.0 0.2 GO:0046540 U4/U6 x U5 tri-snRNP complex(GO:0046540) spliceosomal tri-snRNP complex(GO:0097526)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 5.5 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
1.1 3.3 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.9 2.8 GO:0070568 guanylyltransferase activity(GO:0070568)
0.8 5.6 GO:0003777 microtubule motor activity(GO:0003777)
0.7 2.1 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.7 18.0 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.7 2.7 GO:0009378 four-way junction helicase activity(GO:0009378)
0.6 1.9 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.6 2.8 GO:0000146 microfilament motor activity(GO:0000146)
0.6 2.8 GO:0004707 MAP kinase activity(GO:0004707)
0.5 1.6 GO:0003680 AT DNA binding(GO:0003680)
0.4 1.3 GO:0004100 chitin synthase activity(GO:0004100)
0.4 4.3 GO:0001133 RNA polymerase II transcription factor activity, sequence-specific transcription regulatory region DNA binding(GO:0001133)
0.4 1.6 GO:0004338 glucan exo-1,3-beta-glucosidase activity(GO:0004338)
0.4 1.9 GO:0008536 Ran GTPase binding(GO:0008536)
0.4 3.5 GO:0031386 protein tag(GO:0031386)
0.3 1.0 GO:0004809 tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
0.3 3.0 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.3 1.0 GO:0008097 5S rRNA binding(GO:0008097)
0.3 1.3 GO:0005527 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.3 1.2 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.3 1.2 GO:0001094 TFIID-class transcription factor binding(GO:0001094)
0.3 12.1 GO:0019843 rRNA binding(GO:0019843)
0.3 1.6 GO:0005354 galactose transmembrane transporter activity(GO:0005354)
0.3 1.5 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.3 1.3 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.2 0.7 GO:0047066 phospholipid-hydroperoxide glutathione peroxidase activity(GO:0047066)
0.2 4.1 GO:0001056 RNA polymerase III activity(GO:0001056)
0.2 4.9 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.2 1.6 GO:0019237 centromeric DNA binding(GO:0019237)
0.2 8.2 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.2 0.7 GO:0015088 copper uptake transmembrane transporter activity(GO:0015088)
0.2 1.1 GO:0097372 NAD-dependent histone deacetylase activity (H3-K18 specific)(GO:0097372)
0.2 0.6 GO:0000702 oxidized base lesion DNA N-glycosylase activity(GO:0000702)
0.2 0.6 GO:0004805 trehalose-phosphatase activity(GO:0004805)
0.2 36.4 GO:0003735 structural constituent of ribosome(GO:0003735)
0.2 0.8 GO:0000772 mating pheromone activity(GO:0000772) pheromone activity(GO:0005186)
0.2 0.6 GO:0010521 telomerase inhibitor activity(GO:0010521)
0.2 5.5 GO:0046982 protein heterodimerization activity(GO:0046982)
0.2 1.3 GO:0003968 RNA-directed RNA polymerase activity(GO:0003968)
0.2 0.6 GO:0003951 NAD+ kinase activity(GO:0003951) NADH kinase activity(GO:0042736)
0.2 6.9 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)
0.2 2.8 GO:0033613 activating transcription factor binding(GO:0033613)
0.2 0.6 GO:0001046 core promoter sequence-specific DNA binding(GO:0001046)
0.2 2.2 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.2 1.1 GO:0003993 acid phosphatase activity(GO:0003993)
0.2 0.5 GO:0016717 oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water(GO:0016717)
0.2 0.5 GO:0015166 polyol transmembrane transporter activity(GO:0015166)
0.2 1.2 GO:0019211 phosphatase activator activity(GO:0019211)
0.2 0.5 GO:0051219 phosphoprotein binding(GO:0051219)
0.2 0.5 GO:0005519 cytoskeletal regulatory protein binding(GO:0005519)
0.2 0.5 GO:0003774 motor activity(GO:0003774)
0.2 1.0 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.2 0.3 GO:0051010 microtubule plus-end binding(GO:0051010)
0.2 0.5 GO:0097027 ubiquitin-protein transferase activator activity(GO:0097027)
0.2 0.5 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.2 0.6 GO:0005034 osmosensor activity(GO:0005034)
0.2 0.6 GO:0016634 oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor(GO:0016634)
0.2 3.1 GO:0004520 endodeoxyribonuclease activity(GO:0004520)
0.2 1.5 GO:0030295 protein kinase activator activity(GO:0030295)
0.2 0.5 GO:0015440 peptide-transporting ATPase activity(GO:0015440)
0.1 1.3 GO:0000009 alpha-1,6-mannosyltransferase activity(GO:0000009)
0.1 1.5 GO:0030276 clathrin binding(GO:0030276)
0.1 0.4 GO:0019901 protein kinase binding(GO:0019901)
0.1 2.3 GO:0015616 DNA translocase activity(GO:0015616)
0.1 0.4 GO:0072341 modified amino acid binding(GO:0072341)
0.1 0.4 GO:0005262 calcium channel activity(GO:0005262)
0.1 0.9 GO:0031369 translation initiation factor binding(GO:0031369)
0.1 14.4 GO:0004674 protein serine/threonine kinase activity(GO:0004674)
0.1 0.5 GO:0000297 spermine transmembrane transporter activity(GO:0000297)
0.1 0.6 GO:0008525 phosphatidylcholine transporter activity(GO:0008525) phosphatidylinositol transporter activity(GO:0008526)
0.1 0.9 GO:0031490 chromatin DNA binding(GO:0031490)
0.1 0.5 GO:0008312 7S RNA binding(GO:0008312)
0.1 0.5 GO:0004771 sterol esterase activity(GO:0004771)
0.1 1.3 GO:0043495 protein anchor(GO:0043495)
0.1 0.2 GO:0015248 sterol transporter activity(GO:0015248)
0.1 1.3 GO:0016893 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters(GO:0016893)
0.1 1.9 GO:0031491 nucleosome binding(GO:0031491)
0.1 0.6 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.1 0.7 GO:0001054 RNA polymerase I activity(GO:0001054)
0.1 0.4 GO:0004622 lysophospholipase activity(GO:0004622)
0.1 0.4 GO:0004075 biotin carboxylase activity(GO:0004075)
0.1 0.3 GO:0004311 farnesyltranstransferase activity(GO:0004311)
0.1 0.6 GO:0008641 small protein activating enzyme activity(GO:0008641)
0.1 0.3 GO:0015116 secondary active sulfate transmembrane transporter activity(GO:0008271) sulfate transmembrane transporter activity(GO:0015116)
0.1 0.2 GO:0070300 phosphatidic acid binding(GO:0070300)
0.1 0.3 GO:0004439 phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity(GO:0004439)
0.1 0.4 GO:0016423 tRNA (guanine) methyltransferase activity(GO:0016423)
0.1 0.1 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.1 0.7 GO:0031072 heat shock protein binding(GO:0031072)
0.1 1.4 GO:0030515 snoRNA binding(GO:0030515)
0.1 0.2 GO:0070567 cytidylyltransferase activity(GO:0070567)
0.1 0.6 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.1 0.3 GO:0015230 FAD transmembrane transporter activity(GO:0015230)
0.1 1.4 GO:0015631 tubulin binding(GO:0015631)
0.1 0.2 GO:0009922 fatty acid elongase activity(GO:0009922)
0.1 0.8 GO:0008175 tRNA methyltransferase activity(GO:0008175)
0.1 0.7 GO:0003714 transcription corepressor activity(GO:0003714)
0.1 4.5 GO:0003924 GTPase activity(GO:0003924)
0.1 0.4 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.1 0.3 GO:0001168 transcription factor activity, RNA polymerase I upstream control element sequence-specific binding(GO:0001168)
0.1 0.1 GO:0000171 ribonuclease MRP activity(GO:0000171)
0.1 0.6 GO:0004497 monooxygenase activity(GO:0004497)
0.1 0.3 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.1 0.4 GO:0016408 C-acyltransferase activity(GO:0016408)
0.1 0.6 GO:0019239 deaminase activity(GO:0019239)
0.1 0.3 GO:0001139 transcription factor activity, core RNA polymerase II recruiting(GO:0001139)
0.1 0.2 GO:0000150 recombinase activity(GO:0000150)
0.1 0.6 GO:0008599 protein phosphatase type 1 regulator activity(GO:0008599)
0.1 1.8 GO:0004004 ATP-dependent RNA helicase activity(GO:0004004)
0.1 0.3 GO:0004737 pyruvate decarboxylase activity(GO:0004737)
0.1 0.4 GO:0004620 phospholipase activity(GO:0004620)
0.1 2.5 GO:0005096 GTPase activator activity(GO:0005096)
0.1 0.2 GO:0032183 SUMO binding(GO:0032183)
0.1 0.2 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.1 0.2 GO:0051377 mannose-ethanolamine phosphotransferase activity(GO:0051377)
0.1 0.7 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.1 0.2 GO:0004221 obsolete ubiquitin thiolesterase activity(GO:0004221)
0.1 1.7 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.1 0.1 GO:0005487 nucleocytoplasmic transporter activity(GO:0005487)
0.1 0.6 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.1 1.8 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765)
0.1 0.7 GO:0042277 signal sequence binding(GO:0005048) amide binding(GO:0033218) peptide binding(GO:0042277)
0.1 0.1 GO:0001091 RNA polymerase II basal transcription factor binding(GO:0001091)
0.1 0.2 GO:0016671 oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor(GO:0016671)
0.0 1.2 GO:0061733 histone acetyltransferase activity(GO:0004402) peptide-lysine-N-acetyltransferase activity(GO:0061733)
0.0 3.0 GO:0005543 phospholipid binding(GO:0005543)
0.0 0.1 GO:0030695 GTPase regulator activity(GO:0030695)
0.0 0.2 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.0 0.7 GO:0008080 N-acetyltransferase activity(GO:0008080)
0.0 1.0 GO:0003684 damaged DNA binding(GO:0003684)
0.0 1.5 GO:0019899 enzyme binding(GO:0019899)
0.0 0.9 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 0.2 GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen(GO:0016705)
0.0 0.2 GO:0015198 oligopeptide transporter activity(GO:0015198)
0.0 0.8 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.4 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628)
0.0 0.6 GO:0003713 transcription coactivator activity(GO:0003713)
0.0 0.4 GO:0008301 DNA binding, bending(GO:0008301)
0.0 0.2 GO:0008252 nucleotidase activity(GO:0008252)
0.0 0.4 GO:0016278 lysine N-methyltransferase activity(GO:0016278) protein-lysine N-methyltransferase activity(GO:0016279)
0.0 0.3 GO:0070566 adenylyltransferase activity(GO:0070566)
0.0 0.3 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.0 0.8 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.1 GO:0034595 phosphatidylinositol bisphosphate phosphatase activity(GO:0034593) phosphatidylinositol phosphate 5-phosphatase activity(GO:0034595)
0.0 0.1 GO:0016882 cyclo-ligase activity(GO:0016882)
0.0 0.1 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 0.3 GO:0060589 nucleoside-triphosphatase regulator activity(GO:0060589)
0.0 0.1 GO:0008902 hydroxymethylpyrimidine kinase activity(GO:0008902) phosphomethylpyrimidine kinase activity(GO:0008972)
0.0 0.1 GO:0003725 double-stranded RNA binding(GO:0003725)
0.0 2.0 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.0 0.1 GO:0004326 tetrahydrofolylpolyglutamate synthase activity(GO:0004326)
0.0 0.1 GO:0019202 amino acid kinase activity(GO:0019202)
0.0 0.3 GO:0004521 endoribonuclease activity(GO:0004521)
0.0 0.7 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.3 GO:0016776 phosphotransferase activity, phosphate group as acceptor(GO:0016776)
0.0 0.1 GO:0003727 single-stranded RNA binding(GO:0003727)
0.0 0.4 GO:0043021 ribonucleoprotein complex binding(GO:0043021)
0.0 0.2 GO:0016859 peptidyl-prolyl cis-trans isomerase activity(GO:0003755) cis-trans isomerase activity(GO:0016859)
0.0 0.3 GO:0000386 second spliceosomal transesterification activity(GO:0000386)
0.0 1.2 GO:0008565 protein transporter activity(GO:0008565)
0.0 0.1 GO:0016872 intramolecular lyase activity(GO:0016872)
0.0 0.1 GO:0003756 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0 0.3 GO:0008134 transcription factor binding(GO:0008134)
0.0 0.3 GO:0008289 lipid binding(GO:0008289)
0.0 0.8 GO:0008092 cytoskeletal protein binding(GO:0008092)
0.0 0.4 GO:0019783 ubiquitin-like protein-specific protease activity(GO:0019783)
0.0 0.1 GO:0070491 repressing transcription factor binding(GO:0070491)
0.0 0.4 GO:0050661 NADP binding(GO:0050661)
0.0 0.1 GO:0016504 peptidase activator activity(GO:0016504) endopeptidase regulator activity(GO:0061135)
0.0 0.4 GO:0042393 histone binding(GO:0042393)
0.0 0.1 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.0 0.1 GO:0016886 ligase activity, forming phosphoric ester bonds(GO:0016886)
0.0 0.3 GO:0004721 phosphoprotein phosphatase activity(GO:0004721)
0.0 0.1 GO:0003724 RNA helicase activity(GO:0003724)
0.0 0.8 GO:0003729 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.0 0.1 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 0.0 GO:0003899 DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)
0.0 0.1 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983) transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.0 0.1 GO:0033170 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0 0.1 GO:0000149 SNARE binding(GO:0000149)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.8 PID PLK1 PATHWAY PLK1 signaling events
0.4 1.1 PID SHP2 PATHWAY SHP2 signaling
0.3 0.9 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.3 1.2 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.2 0.7 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.2 2.0 NABA MATRISOME Ensemble of genes encoding extracellular matrix and extracellular matrix-associated proteins
0.2 0.4 PID FOXO PATHWAY FoxO family signaling
0.2 1.5 PID ATR PATHWAY ATR signaling pathway
0.1 0.4 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.1 0.5 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.1 0.2 PID P73PATHWAY p73 transcription factor network
0.1 0.2 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.1 0.4 PID TELOMERASE PATHWAY Regulation of Telomerase
0.1 0.2 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 0.1 PID MYC PATHWAY C-MYC pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 12.6 REACTOME 3 UTR MEDIATED TRANSLATIONAL REGULATION Genes involved in 3' -UTR-mediated translational regulation
0.5 1.4 REACTOME SIGNALLING TO ERKS Genes involved in Signalling to ERKs
0.4 2.9 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.4 4.7 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.4 1.2 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.3 0.6 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.2 1.4 REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.2 0.4 REACTOME G1 PHASE Genes involved in G1 Phase
0.2 0.4 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.2 0.3 REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements
0.1 0.5 REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS Genes involved in Glycerophospholipid biosynthesis
0.1 0.2 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.1 0.5 REACTOME G ALPHA I SIGNALLING EVENTS Genes involved in G alpha (i) signalling events
0.1 0.6 REACTOME DNA STRAND ELONGATION Genes involved in DNA strand elongation
0.1 0.3 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.1 1.2 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.1 0.6 REACTOME TRANSLATION Genes involved in Translation
0.1 0.6 REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.1 0.1 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.1 0.2 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.1 0.2 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.1 0.2 REACTOME CIRCADIAN CLOCK Genes involved in Circadian Clock
0.0 0.4 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0 0.1 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.1 REACTOME NUCLEAR SIGNALING BY ERBB4 Genes involved in Nuclear signaling by ERBB4
0.0 0.1 REACTOME RNA POL II TRANSCRIPTION Genes involved in RNA Polymerase II Transcription
0.0 0.1 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.0 0.2 REACTOME METABOLISM OF MRNA Genes involved in Metabolism of mRNA
0.0 0.1 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
0.0 0.1 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression